CN1049594C - Rubber plaster for hyperosteogeny - Google Patents

Rubber plaster for hyperosteogeny Download PDF

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Publication number
CN1049594C
CN1049594C CN94117460A CN94117460A CN1049594C CN 1049594 C CN1049594 C CN 1049594C CN 94117460 A CN94117460 A CN 94117460A CN 94117460 A CN94117460 A CN 94117460A CN 1049594 C CN1049594 C CN 1049594C
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China
Prior art keywords
hyperosteogeny
rhizoma
adhesive plaster
coated
percolation
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Expired - Fee Related
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CN94117460A
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Chinese (zh)
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CN1107732A (en
Inventor
吕秀兰
熊维政
丁福友
张军斌
刘智慧
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HENAN LINGRUI PHARMACEUTICAL CO Ltd
XINMI CITY OSTEOPROLIFERATION INST
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HENAN LINGRUI PHARMACEUTICAL CO Ltd
XINMI CITY OSTEOPROLIFERATION INST
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Priority to CN94117460A priority Critical patent/CN1049594C/en
Publication of CN1107732A publication Critical patent/CN1107732A/en
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Publication of CN1049594C publication Critical patent/CN1049594C/en
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Abstract

The present invention relates to an adhesive plaster for treating hyperosteogeny in clinic for patients, which is prepared in a such manner that mixed percolating liquid prepared from angelica, pricklyash peel, hemlock parsley, safflower, rhubarb, pepper fruit, cassia bark, dried ginger, clove, Rhizoma Kaempferiae, long pepper, camphor, borneol and menthol and ethanol is added to a base material composed of rubber and rosin to prepare paste; the paste is smeared on a piece of base cloth, and a plastic protection layer is covered on the surface of the paste. The adhesive plaster has the advantages of convenient use, portability, high curative effect, simple preparation technique, low cost, easy production, popularization and application, and obvious social and economic benefits.

Description

Adhesive plaster for curing hyperosteogeny
The present invention relates to a kind of invalid adhesive plaster for curing hyperosteogeny of hyperosteogeny (because of rubber cream takes effect pasting, so claim GUZHIZENGSHENG YITIELING again) for the treatment of clinically.
Hyperosteogeny is the common a kind of retrograde change of human body, is a kind of defensive reaction that human body produces for the variation that adapts to stress.But, when outgrowth sclerotin pressuring nerve, blood vessel etc. are organized, bone matrix hyperplasia not busy condition of illness will appear facing accordingly, i.e.; Sclerotin has calcific deposit around the joint, and the bone at edge, joint has exostosis, and it is unfavorable to bring for patient body health, and the sense of pain is particularly arranged, even has brought inconvenience for normal activity, life.The many employings of present treatment to hyperosteogeny are taken medicine and are equipped with auxiliary external used medicine, but effect is still not ideal, and the taking and use all cumbersome of medicine, as the medicinal preparation for oral administration of using clinically, use trouble, slow, the complex manufacturing of taking effect, cost height, it is applied and is restricted, and this and patient are disadvantageous.
It is exactly actual needs at the hyperosteogeny patient that purpose of the present invention has, and provides a kind of adhesive plaster for curing hyperosteogeny in conjunction with the way of Chinese medical theory and inner disease outer treat.
The object of the present invention is achieved like this, belong to the traditional Chinese medical science " arthromyodynia " category according to hyperosteogeny, be similar to " rheumatism involving the bone ", because its pathogenesis key is " numbness and obstructed ", so in treatment, answer " symptomatic treatment in acute condition ", with " leading to " is usefulness, with blood circulation promoting and blood stasis dispelling, and the cold expelling collateral dredging, remove the wind damp eliminating, deep pain relieving is a principle of treatment, and general rule to be to take stopgap measures, the clinical condition of illness of very fast alleviation.For this reason, Chinese medicine and pharmacy in conjunction with China's preciousness, adopt Radix Angelicae Sinensis, Rhizoma Chuanxiong, Fructus Piperis, Flos Caryophylli, Cortex Cinnamomi, Radix Et Rhizoma Rhei, Borneolum Syntheticum, Mentholum, Camphora etc. to contain the medical material of plurality of active ingredients such as volatility and glycoside, through carrying out percolation, collect and make thick paste, and add the substrate of making by rubber, Colophonium etc. (on sale on the substrate market) with ethanol, make again and be coated with cream, carry out coating, cutting, lid lining, be cut into small pieces, promptly get adhesive plaster for curing hyperosteogeny.
The present invention portably uses conveniently, instant effect, and evident in efficacy, so claim GUZHIZENGSHENG YITIELING again, production technology is simple, material is abundant, cost is low, be easy to apply, the society and economy remarkable benefit.
Describe formation situation of the present invention in detail below in conjunction with embodiment.
Radix Angelicae Sinensis: hot, bitter, temperature, promote blood circulation and benefaction antalgic; Rhizoma Chuanxiong: blood-activating and qi-promoting, wind-expelling pain-stopping.The Compendium of Material Medica cloud: " Rhizoma Chuanxiong, its property is kind looses, and walks Liver Channel again, the blood medicine in the gas is also ".Rhizoma Chuanxiong, Radix Angelicae Sinensis all belong to the blood medicine, and the merit of loosing of Rhizoma Chuanxiong is more so in Radix Angelicae Sinensis, thus can dispersing wind and cold, control headache, removing blood stasis with potent drugs blood, promoting blood circulation is separated stagnation of QI, the pain that relieves the pain, the evacuation of pus detumescence is pursued blood and is stimulated the menstrual flow.Two medicines are usefulness at the main pathogenesis of hyperosteogeny pain to lead to, and general rule is a monarch drug not bitterly altogether; Flos Carthami: Xin Wen goes into the conscience warp.Merit tool promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing; Rhizoma Kaempferiae: warming middle-JIAO to relieve pain, " product converge with essence will " be sayed its wind-expelling pain-stopping; Pericarpium Zanthoxyli, Fructus Piperis: dispelling cold by warming the meridian, promoting the circulation of QI to relieve pain.Four medicines all are usefulness with the pain relieving, each tool different characteristics again, and the power of principal drug assistance is ministerial drug altogether; Flos Caryophylli, Cortex Cinnamomi: the heresy of outer dispersing wind and cold, the fire of interior the kidney invigorating life; Fructus Piperis Longi: warming middle-JIAO to send down the adverse QI; Rhizoma Zingiberis: the warming the interior cold expelling join the product of invigorating blood circulation with the hot medicine of this group, but the dispelling cold by warming the meridian collateral dredging with the wind-cold damp pathogen of dispelling passages through which vital energy circulates muscles and bones, and in can deeply reaching, is an adjuvant drug altogether; Radix Et Rhizoma Rhei: bitter cold, eliminating blood stasis and inducing menstruation both can press down product consumptions impairment of YIN Tianjin of the hot warm-dryness syndrome of group, but eliminating blood stasis and inducing menstruation again; Borneolum Syntheticum, Camphora, Mentholum are all the product that Xin Xiang walks to scurry, but priming reaching disease institute, and the merit of tool reducing swelling and alleviating pain." ginseng west record in doctor's inner feelings " speech: " the Herba Menthae acrid in the mouth, gas delicate fragrance is scurried, and property is flat.Saturating muscles and bones in its power energy reaches the flesh table outward, and the logical internal organs of a surname pass through and scurry meridians ... the limbs contracture is had a pain, and the disease that all wind-fire are hot and suffocating all can be controlled it." above-mentioned several flavors, be messenger drug altogether.The etiology and pathogenesis of the complete square bone matrix hyperplasia that links closely is a usefulness with " leading to ", plays blood circulation promoting and blood stasis dispelling altogether, cold expelling collateral dredging, expelling wind and removing dampness, the merit of deep pain relieving.
Adhesive plaster for curing hyperosteogeny (claiming GUZHIZENGSHENG YITIELING again) produce by be coated with cream be coated on the base fabric and on be coated with cream the lining lid constitute with protective layer; it is coated with cream is by 100 parts of (parts by weight) Radix Angelicae Sinensis; 52 parts of Rhizoma Chuanxiongs; 72 parts in Pericarpium Zanthoxyli; 52 parts on Flos Carthami; 52 parts of Radix Et Rhizoma Rhei; 52 parts in Fructus Piperis; 52 parts of Cortex Cinnamomis; 52 parts of Rhizoma Zingiberiss; 30 parts of Flos Caryophyllis; 52 parts of Rhizoma Kaempferiae; 52 parts of Fructus Piperis Longi; 124 parts of Camphoras; 30 parts of Borneolum Syntheticums; Mentholum is a medicine material for 30 parts; at first will be except that Camphora; Borneolum Syntheticum; other ten Herba indigoferae Pseudotinctoriae beyond the Mentholum are made powder; with percolation after 90% alcohol dipping; in the percolate of receiving; adding is with the Camphora of each explosive component metering; Borneolum Syntheticum; Mentholum is made and is mixed the liquid of just filtering; mix with the percolation concentrated extract that 65% ethanol continues percolation with medicinal residues again; the mixing percolation that constitutes twice extracts spissated mixing extractum; add again 3.0~3.2 times by rubber; the substrate that Colophonium is formed stirs evenly and becomes to be coated with cream; being coated with cream is evenly coated on the base fabric; medicine is coated with cream face lining lid protection plastic layer; through stripping and slicing; section promptly constitutes required adhesive plaster for curing hyperosteogeny (claiming GUZHIZENGSHENG YITIELING again).The component of above-mentioned medicine raw material can weight ratio be written as again:
Radix Angelicae Sinensis: Rhizoma Chuanxiong: Pericarpium Zanthoxyli: Flos Carthami: Radix Et Rhizoma Rhei: Fructus Piperis: Cortex Cinnamomi: Rhizoma Zingiberis: Flos Caryophylli: Rhizoma Kaempferiae: Fructus Piperis Longi: Camphora: Borneolum Syntheticum: Mentholum=100: 52: 72: 52: 52: 52: 52: 52: 30: 52: 52: 124: 30: 30.
To constitute 7 * 10cm 21000 adhesive plaster for curing hyperosteogeny be example, component of the present invention is described in detail specifically in detail and the formation situation is as follows:
By Radix Angelicae Sinensis 100g; Rhizoma Chuanxiong 52g; Pericarpium Zanthoxyli 72g; Flos Carthami 52; Radix Et Rhizoma Rhei 52g; Fructus Piperis 52g; Cortex Cinnamomi 52g; Rhizoma Zingiberis 52g; Flos Caryophylli 30g; Rhizoma Kaempferiae 52g; Fructus Piperis Longi 52g; Camphora 124g; Borneolum Syntheticum 30g; Mentholum 30g; after handling totally; at first with Radix Angelicae Sinensis; Rhizoma Chuanxiong; Pericarpium Zanthoxyli; Flos Carthami; Radix Et Rhizoma Rhei; Fructus Piperis; Cortex Cinnamomi; Rhizoma Zingiberis; Flos Caryophylli; Rhizoma Kaempferiae; Fructus Piperis Longi ten medical material is simply handled respectively and is made the coarse powder shape; according to the percolation under fluid extract and the extractum item (seeing 17 pages of appendix of Chinese Pharmacopoeia nineteen ninety version); after each medicated powder mixing; put into the percolation container; carry out percolation after 24 hours with 90% alcohol dipping; keep percolation to exceed powder 10cm with ethanol; speed percolation with per 100 gram medicine per minute 3-6ml; collect the liquid 400ml that just filters; camphorate; Borneolum Syntheticum; Mentholum; stirring and dissolving becomes the mixed liquor of just filtering; airtight preservation; medicinal residues reuse 65% ethanol behind the percolation continues percolation for the first time; the collection liquid 2500ml that filters that continues; the continue liquid of filtering of 2500ml is concentrated into the 200g thick paste; with the primary Camphora that added; Borneolum Syntheticum; the first liquid of filtering of Mentholum is mixed into mixing extractum; after weighing; add 3.0~3.2 times of weight by rubber; the substrate that Colophonium etc. constitute; the composition by weight ratio that promptly mixes extractum and substrate is 1 to 3.0~3.2; just mix extractum 3.0~3.2 parts substrate mix homogeneously together with 1 part; make and be coated with cream; be coated on the base fabric; cover the protection plastic layer on the powder, by 7 * 10cm 3Requirement be cut into 1000, can become the adhesive plaster for curing hyperosteogeny (claiming GUZHIZENGSHENG YITIELING again) of usefulness that local skin pastes.
By above-mentioned situation as can be seen, the present invention is with traditional technology, and new component is produced the new drug with significant curative effect, and its function is blood circulation promoting and blood stasis dispelling, cold expelling collateral dredging, removes the wind damp eliminating, and deep pain relieving can cure mainly:
1, the various pain that caused by hyperosteogeny, limbs are heavy to be stranded, numb, movable unfavorable, stiffness of the neck, dizziness and tinnitus.
2, calcanean spur;
3, acute and chronic rheumatism, rheumatoid arthritis, scapulohumeral periarthritis, sciatica, lumbar muscle strain, prolapse of intervertebral disc, nameless gall;
4, because of wind, cold, various symptoms that arthralgia chiefly caused by damp pathogen causes.
The present invention conforms to quality requirements fully, and through three batch samples are detected, its result is as follows:
Lot number 940217 940220 940224 GB
Relative density 1.11 1.12 1.13
Volatility ligroin extraction content (g/100ml) 19.6 18.1 18.7 >15.0
Fixedness ligroin extraction content (g/100ml) 1.35 1.42 1.49 >1.2
Paste containing amount (g/100ml) 1.7928 1.8015 1.7842 >1.6
The present invention is faint yellow lamellar rubber cream, and fragrant odour has no side effect, and the people is on probation surplus ten thousand, and effective percentage sees the following form more than 87.6%:
Sick class Pain Ache Heavy being stranded Numb Movable unfavorable
Henan Province institute of traditional Chinese medicine of Henan Prov. People's Hospital 98.1 92.3 95.7 90.5 95.0 87.6 88.4 89.3 94.7 91.2
Through relatively, obviously be better than Musk Analgesic Plaster with Musk Analgesic Plaster treatment bone matrix hyperplasia.With the Qinghai Musk Analgesic Plaster is that example is compared as follows:
Adhesive plaster for curing hyperosteogeny The Qinghai Emplastrum Moschus
Case Produce effects Effectively Invalid Case Produce effects Effectively Invalid
Pain 53 22 30 1 29 3 18 8
Ache 48 20 26 2 27 2 15 10
Heavy being stranded 41 18 30 2 21 2 9 10
Numb 26 10 13 3 14 0 2 12
Movable unfavorable 58 22 33 3 19 1 5 13
In clinic trial, to individual patients can cause skin rubefaction, skin hypersensitivity reaction such as have an itch, but can die away after the drug withdrawal, other have no side effect to whole body.Of the present invention succeed in developing and apply welcome by extensive patients, and produce remarkable social benefit and economic worth.

Claims (1)

1. adhesive plaster for curing hyperosteogeny for the treatment of hyperosteogeny, it is characterized in that by Radix Angelicae Sinensis 100g, Rhizoma Chuanxiong 52g, Pericarpium Zanthoxyli 72g, Flos Carthami 52g, Radix Et Rhizoma Rhei 52g, Fructus Piperis 52g, Cortex Cinnamomi 52g, Rhizoma Zingiberis 52g, Flos Caryophylli 30g, Rhizoma Kaempferiae 52g, the mixed powder grain that Fructus Piperis Longi 52g constitutes by 90% alcohol dipping after percolation become the liquid 400ml that just filters, 124g camphorates, Borneolum Syntheticum 30g, Mentholum 30g stirs evenly and forms the mixed liquor of just filtering, for the first time filter through continuing with the 65% ethanol percolation gained 2500ml concentrated thick paste 200g of liquid of the medicinal residues behind the percolation is mixed into the mixed liquor of just filtering and mixes extractum, mixing extractum is coated with cream with 3.0~3.2 times substrate composition, it is coated with cream and is coated in uniformly on the base fabric, constitutes 7 * 10cm 21000 adhesive plaster for curing hyperosteogeny.
CN94117460A 1994-10-19 1994-10-19 Rubber plaster for hyperosteogeny Expired - Fee Related CN1049594C (en)

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Application Number Priority Date Filing Date Title
CN94117460A CN1049594C (en) 1994-10-19 1994-10-19 Rubber plaster for hyperosteogeny

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Application Number Priority Date Filing Date Title
CN94117460A CN1049594C (en) 1994-10-19 1994-10-19 Rubber plaster for hyperosteogeny

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CN1049594C true CN1049594C (en) 2000-02-23

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107050208A (en) * 2017-04-12 2017-08-18 王明贵 A kind of medicinal liquor for treating osteoproliferation, protrusion of lumber intervertebral disc, cervical vertebra hyperplasia, rheumatism and rheumatoid disease

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1045032A (en) * 1989-02-27 1990-09-05 马淑玉 The compound method of GUCITING plaster

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1045032A (en) * 1989-02-27 1990-09-05 马淑玉 The compound method of GUCITING plaster

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
四川中医1985,3(2) 1985.2.28 董治能,验方治疗骨质增生 *
辽宁中医杂志1985,9(8) 1985.8.31 于霖,应用超声波和活血化瘀中药治疗骨质增生20例 *
辽宁中医杂志1985,9(8) 1985.8.31 于霖,应用超声波和活血化瘀中药治疗骨质增生20例;四川中医1985,3(2) 1985.2.28 董治能,验方治疗骨质增生 *

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