CN104948549A - POCT chip product fast flexible bonding sealing machine - Google Patents
POCT chip product fast flexible bonding sealing machine Download PDFInfo
- Publication number
- CN104948549A CN104948549A CN201510346973.5A CN201510346973A CN104948549A CN 104948549 A CN104948549 A CN 104948549A CN 201510346973 A CN201510346973 A CN 201510346973A CN 104948549 A CN104948549 A CN 104948549A
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- Prior art keywords
- flexible
- rigidity
- plate
- top board
- guide rod
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 238000007789 sealing Methods 0.000 title claims abstract description 40
- 238000012123 point-of-care testing Methods 0.000 title claims abstract description 15
- 238000007667 floating Methods 0.000 claims abstract description 10
- 238000004826 seaming Methods 0.000 claims description 24
- 238000001514 detection method Methods 0.000 claims description 15
- 239000003292 glue Substances 0.000 claims description 11
- 238000004528 spin coating Methods 0.000 claims description 6
- 239000012528 membrane Substances 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 3
- 239000011505 plaster Substances 0.000 claims 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 1
- 229910002027 silica gel Inorganic materials 0.000 claims 1
- 239000000741 silica gel Substances 0.000 claims 1
- 229960001866 silicon dioxide Drugs 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 26
- 238000005303 weighing Methods 0.000 abstract 1
- 238000004026 adhesive bonding Methods 0.000 description 10
- 230000000694 effects Effects 0.000 description 6
- 239000000758 substrate Substances 0.000 description 5
- 238000003754 machining Methods 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 230000035882 stress Effects 0.000 description 2
- 239000003522 acrylic cement Substances 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000008646 thermal stress Effects 0.000 description 1
- 238000002834 transmittance Methods 0.000 description 1
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16B—DEVICES FOR FASTENING OR SECURING CONSTRUCTIONAL ELEMENTS OR MACHINE PARTS TOGETHER, e.g. NAILS, BOLTS, CIRCLIPS, CLAMPS, CLIPS OR WEDGES; JOINTS OR JOINTING
- F16B11/00—Connecting constructional elements or machine parts by sticking or pressing them together, e.g. cold pressure welding
- F16B11/006—Connecting constructional elements or machine parts by sticking or pressing them together, e.g. cold pressure welding by gluing
Abstract
A POCT chip product fast flexible bonding sealing machine comprises a pressure cylinder (1), a pneumatic system, guide rods, a floating connector, a guide rod connecting plate, a flexible upper pressing plate, a rigid lower pressing plate, sliding sleeves, an upper plate, a rigid upper pressing plate, stand columns, a flexible lower pressing plate, a sensor connecting plate, a sensor and detecting system and a lower plate. The pneumatic system drives the pressure cylinder, a flexible upper pressing head moves downwards in the work process, and is in contact with a chip to provide pressure, sealing is completed, flexile design is adopted in the upper pressing head and a lower pressing head, and the problem that due to the fact that the chip is not flat or the pressing heads are not flat, sealing is difficult can be effectively solved in the sealing process. Self-adaption adjusting design is adopted in the upper pressing head, the straightness and perpendicularity of the upper pressing head are guaranteed, the lower pressing head is fixed with a weighing sensor, the centering performance of the lower pressing head and the upper pressing head is good, and the structure is simple. The quality and speed of bonding sealing can be effectively improved through the design of the whole machine, and a foundation is laid for bonding sealing automation.
Description
Technical field
The present invention relates to the instant detection chip product of POCT, for the flexible splicing sealing equipment of the instant detection chip of POCT.
Background technique
POCT refers to any detection by carrying out beyond hospital professional person or the layman in the detection heart, referred to as real-time test.Compared with detecting with traditional centralized laboratories, instant detect (point of care testing, POCT) has and obtains experimental result fast, simple operation, and sample consumption is few, uses the features such as whole blood sample.But by the POCT output based on chip lab, one of key issue to be solved is exactly the involution of chip.Namely involution is the sealing of substrate and cover plate, completes the making of chip, is a key technology of micro-system encapsulation.Can involution be of poor quality, easily causes chip leakage, cannot seal, and also affects chip outward appearance in addition, use so the quality of involution quality directly affects chip, and it is vital process step in chip fabrication processes.
Sealing method conventional at present has ultrasonic involution, directly heat sealing and gluing involution, and ultrasonic involution surface needs to manufacture microstructure and carries out melting involution, and add manufacture difficulty, and the process parameter of required control is many, technique is unstable; Direct heat sealing generally adopts the mode of overall heating, and adjoint can produce thermal stress, length consuming time.
The gluing involution that connects is the method being realized involution by the middle resisting medium between substrate and cover plate, compared with traditional sealing method, gluingly connects sealing method lot of advantages.
1. process parameter requires simple, only need control sealing pressure and dwell time.
2. using scope is wide, is applicable to the involution of most of polymer chip.
3. cost is low, and do not need heating, need to keep bioactive chip for biological detection one class, the gluing involution that connects can complete involution fast at normal temperatures.
There is many advantages in the gluing involution that connects, but also has its shortcomings and limitations.Relative to other sealing methods, still there are some problems in the current gluing involution that connects in involution outward appearance, involution quality, automaticity etc.First, chip easily produces defect, and involution is incomplete, and chip local easily produces bubble, and affect chip sealing, along with the rising of sealing pressure, micro structure array is easily out of shape even conquassation.Secondly, automaticity is low, for adopting the gluing POCT instant detection chip product connecing involution mostly by manual involution at present, and length consuming time, involution weak effect.
Therefore, design the gluing automation equipment connecing involution of the instant detection chip of a POCT of being applicable to be very important.
Summary of the invention
The present invention is intended to solve the problem, provide a kind of for the gluing bonding sealing machine of flexible glue connecing involution of the instant detection chip of POCT, this machine is made up of cylinder and pneumatic system, guide rod, floating junction, guide rod connecting plate, flexible top board, rigidity press table, sliding sleeve, upper plate, rigidity top board, column, flexible press table, sensor connecting plate, sensor and detection system, lower plate.It is characterized in that:
Driver element selects the pressurized cylinder with the extrusion pressure that increases, and the pressurized cylinder scope of exerting oneself is 0-1000kg, and the piston rod scope of stretching out is 0-200mm, by four socket head screws, pressurized cylinder is fixed on upper plate; This kind of cylinder has very large advantage for involution large size, heavy thickness and rough chip;
Hole is got through at upper plate center, and diameter is greater than pressurized cylinder piston bar 2mm; Upper plate each side has a through hole, through hole machining tolerance H7, and each through hole is built with two flanged (FLGD) sliding sleeves, and sliding sleeve symmetry is fixed in through hole, sliding sleeve and through hole interference fit;
The flexible top board be fixed together up and down, rigidity top board, guide rod connecting plate form the flexible seaming chuck of sealing machine; Cross section is that the rigidity top board of rectangle is connected with guide rod connecting plate socket head screw, and the rigidity top board tapped hole degree of depth is less than rigidity top board thickness.Flexible top board cross section is rectangle, and size is identical with rigidity top board, uses glue spin coating, is fitted on rigidity top board fixing; Seaming chuck is connected with pressurized cylinder piston bar by floating junction, and when pressure head produces bias or inclination due to unbalance stress, floating junction can realize automatic adjustment, prevents location.Flexible seaming chuck can play in the process pressed down increase substrate and cover plate area of contact, reduce the bubble produced in sealing process, the effect improving involution effect;
Guide rod end face circle centre position has attacked tapped hole, is fixed on guide rod connecting plate with inverted socket head screw, each side one, and be relatively arranged symmetrically with flexible seaming chuck, guide rod machining tolerance is h9, and process straightness accuracy, cylindricity has required precision; Guide rod and guide rod connecting plate stationary plane have planarity requirements; Guide rod adopts Spielpassung with the sliding sleeve being fixed on frame upper plate, and during pressurized cylinder work, guide rod guides seaming chuck moving linearly in sliding sleeve;
The flexible press table be fixed together up and down, rigidity press table, sensor connecting plate and sensor form the flexible push-down head of sealing machine; Sensor is fixed on the central position of lower plate, connects with inverted socket head screw; Sensor connecting plate upper part cross section is rectangle, and lower part cross section is circular, and counter sink has been attacked at center, is fixed by socket head screw with sensor.In order to ensure smoothness and the flatness of push-down head plane, the smooth rigidity push-down head of working surface is placed in above sensor connecting plate, size is identical with sensor connecting plate, and adopt socket head screw to be inverted and tighten, rigidity press table thickness is greater than the tapped hole degree of depth of processing; Flexible press table size is consistent with rigidity press table, by glue spin coating, is fitted on rigidity press table fixing; Play the area of contact of increase substrate and cover plate in the process that flexible push-down head can press down at seaming chuck, reduce the bubble produced in sealing process, the effect improving involution effect;
Four column type frames are made up of upper plate, column, lower plate, four measure-alike columns are fixed by socket head screw and upper and lower plate, column is processed with straightness accuracy and cylindricity requirement, upper plate and lower plate cross section are rectangle, size is identical, and lower plate and sensor stationary plane have planeness and roughness requirements; The counter sink of lower plate and the center hole of upper plate have coaxality requirement;
The length and width of flexible glue bonding sealing machine seaming chuck and push-down head cross section rectangle are measure-alike, and rigidity top board and rigidity press table parallelism have requirement;
This kind of instant detection chip of POCT is gluing connects sealing machine, and seaming chuck, push-down head all adopt rubber flexible material;
This kind of POCT instant detection chip adhesive sealing machine, involution chip two-sided glued membrane used adopts the two-sided glued membrane of OCA optics, and this kind of glued membrane is a kind of Double-face adhesive rubber alloy band without body material, and made by optics acryl glue, its transmittance can reach 98%.
Beneficial effect of the present invention is that, except involution is effective, involution rate is high, and sealing machine work is rapid, automatically can stop, effectively raising automaticity after fixed cycle operator; Pressure in sealing process can implement display, plays a significant role the process parameter optimizing involution; And the pressure head uniform force optimized, is not easy bias.
Accompanying drawing explanation
Fig. 1 is the mechanical structure schematic diagram of entirety of the present invention.
Fig. 2 A is the structural representation of flexible seaming chuck.
Fig. 2 B is the structural representation of flexible push-down head.
Fig. 3 is the structural representation of guide rod.
Fig. 4 is the structural representation of frame.
Fig. 5 is the structural representation of sliding sleeve.
Fig. 6 is the special floating junction structural representation of pressurized cylinder.
Fig. 7 is the structural representation of sensor connecting plate.
1 pressurized cylinder and pneumatic system in figure; 2 guide rods; 3 floating junctions; 4 guide rod connecting plates; 5 flexible top boards; 6 rigidity press tables; 7 sliding sleeves; 8 upper plates; 9 rigidity top boards; 10 columns; 11 flexible press tables; 12 sensor connecting plates; 13 sensors and detection system; 14 lower plates.
Embodiment
Below in conjunction with accompanying drawing, concrete real-time mode of the present invention is described:
Pressurized cylinder 1 is fixed on upper plate 8, and pressurized cylinder 1 is driven by pneumatic system, makes flexible seaming chuck stretch out retraction;
Hole is got through at upper plate 8 center, and diameter is greater than pressurized cylinder 1 piston rod 2mm; Upper plate 8 each side processes a through hole, through hole machining tolerance H7, and each through hole is built with two flanged (FLGD) sliding sleeves 7, and sliding sleeve 7 symmetry is fixed in through hole, sliding sleeve and through hole interference fit;
The flexible top board 5 be fixed together up and down, rigidity top board 9, guide rod connecting plate 4 form the flexible seaming chuck of sealing machine, as shown in Figure 2 A; Cross section is that the rigidity top board 9 of rectangle is connected with socket head screw with guide rod connecting plate 4, and the rigidity top board 9 tapped hole degree of depth is less than rigidity top board 9 thickness.Flexible top board 5 cross section is rectangle, and size is identical with rigidity top board 9, uses glue spin coating, is fitted on rigidity top board 9 fixing; Flexible seaming chuck is connected with pressurized cylinder 1 piston rod by floating junction 3, and when pressure head produces bias or inclination due to unbalance stress, floating junction can realize automatic adjustment; In the process of involution chip, seaming chuck completes chip involution by providing pressure;
Guide rod 2 end face circle centre position has attacked tapped hole, is fixed on guide rod connecting plate 4 with inverted socket head screw, and each side one, guide rod machining tolerance is h9, and process straightness accuracy, cylindricity has required precision; Guide rod 2 and guide rod connecting plate 4 stationary plane have planarity requirements; Guide rod 2 adopts Spielpassung with the sliding sleeve 7 being fixed on frame upper plate 8, and when pressurized cylinder 1 works, guide rod 2 guides flexible seaming chuck moving linearly in sliding sleeve 7;
Sealing machine can realize accurate centering by the flexible seaming chuck of guide rod 2 fixed guide with the flexible push-down head being fixed on lower plate 14.The length and width of flexible seaming chuck and flexible push-down head cross section rectangle are measure-alike, and rigidity top board 9 and rigidity press table 6 parallelism have requirement;
The flexible press table 11 be fixed together up and down, rigidity press table 6, sensor connecting plate 12 and sensor 13 form the flexible push-down head of sealing machine, as shown in Figure 2 B; Sensor 13 is fixed on the central position of lower plate 14, connects with inverted socket head screw; Sensor connecting plate 12 upper part cross section is rectangle, and lower part cross section is circular, and counter sink has been attacked at center, is fixed by socket head screw with sensor 13.The smooth rigidity push-down head 6 of working surface is placed in above sensor connecting plate 12, and size is identical with sensor connecting plate 12, and adopt socket head screw to be inverted and tighten, rigidity press table 6 thickness is greater than the tapped hole degree of depth of processing; Flexible press table 11 size is consistent with rigidity press table 6, by glue spin coating, is fitted on rigidity press table 6 fixing; The flexible portion of push-down head can play the effect increasing substrate and cover sheet into contact area in the process of seaming chuck supercharging;
Four column type frames are made up of upper plate 8, column 10, lower plate 14, four measure-alike columns 10 are fixed by socket head screw and upper plate 8, lower plate 14, column 10 is processed with straightness accuracy and cylindricity requirement, upper plate 8 and lower plate 14 cross section are rectangle, size is identical, and lower plate 14 and sensor 13 stationary plane have planeness and roughness requirements; The counter sink of lower plate 14 and the center hole of upper plate 8 have coaxality requirement;
Concrete operating process is as follows:
After air pump starts air feed, arrange sealing time, adjustment gas pressure, after accomplishing the setting up press start button, now pressure head stretches out fast, starts to provide set pressure after flexible seaming chuck touches chip, starts to carry out pressurize after reaching pressure.
If reach the dwell time, involution is complete, and flexible seaming chuck lifts automatically, gets back to initial position, takes off chip, repeats said process.
Claims (5)
1. the quick flexible splicing sealing machine of POCT instant detection chip product, comprises pressurized cylinder and pneumatic system (1), guide rod (2), floating junction (3), guide rod connecting plate (4), flexible top board (5), rigidity press table (6), sliding sleeve (7), upper plate (8), rigidity top board (9), column (10), flexible press table (11), sensor connecting plate (12), sensor and detection system (13) and lower plate (14); It is characterized in that:
Driver element selects pressurized cylinder (1), and pressurized cylinder (1) exerts oneself scope at 0-1000kg, and the piston rod scope of stretching out is 0-200mm, by four socket head screws, pressurized cylinder (1) is fixed on upper plate (8);
Hole is got through at upper plate (8) center, and diameter is greater than pressurized cylinder (1) piston rod 2mm; Upper plate (8) each side has a through hole, and each through hole is built with two flanged (FLGD) sliding sleeves (7), and sliding sleeve (7) symmetry is fixed in through hole, sliding sleeve and through hole interference fit;
The flexible top board (5) be fixed together up and down, rigidity top board (9), guide rod connecting plate (4) form the flexible seaming chuck of sealing machine; Cross section is that the rigidity top board (9) of rectangle is fixed on guide rod connecting plate (4) center, and connects with socket head screw, and rigidity top board (9) the tapped hole degree of depth is less than rigidity top board (9) thickness; Flexible top board (5) cross section is rectangle, and size is identical with rigidity top board (9), uses glue spin coating, is fitted in rigidity top board (9) upper fixing; Flexible seaming chuck is connected with pressurized cylinder (1) piston rod by floating junction (3);
Guide rod (2) end face circle centre position has attacked tapped hole, is fixed on guide rod connecting plate (4), each side one, is arranged symmetrically with relative to flexible seaming chuck with inverted socket head screw; Guide rod (2) and guide rod connecting plate (4) stationary plane have planarity requirements; Guide rod (2) adopts Spielpassung with the sliding sleeve (7) being fixed on frame upper plate (8), and during pressurized cylinder (1) work, guide rod (2) guides flexible seaming chuck moving linearly in sliding sleeve (7);
The flexible press table (11) be fixed together up and down, rigidity press table (6), sensor connecting plate (12) and sensor (13) form the flexible push-down head (B) of sealing machine; Sensor (13) is fixed on the central position of lower plate (14), connects with inverted socket head screw; Sensor connecting plate (12) upper part cross section is rectangle, and lower part cross section is circular (8), and counter sink has been attacked at center, is fixed by socket head screw with sensor (13); The smooth rigidity press table (6) of working surface is placed in sensor connecting plate (12) top, size is identical with sensor connecting plate (12), adopt socket head screw to be inverted to tighten, rigidity press table (6) thickness is greater than the tapped hole degree of depth of processing; Flexible press table (11) size is consistent with rigidity press table (6), by glue spin coating, is fitted in rigidity press table (6) upper fixing;
Four column type frames are made up of upper plate (8), column (10), lower plate (14), four measure-alike columns (10) are fixed by socket head screw and upper and lower plate (8,14), column (10) is processed with straightness accuracy and cylindricity requirement, upper plate (8) and lower plate (14) cross section are rectangle, size is identical, and lower plate (14) and sensor (13) stationary plane have planeness and roughness requirements; The counter sink of lower plate (14) and the center hole of upper plate (8) have coaxality requirement.
2. the bonding sealing machine of flexible glue according to claim 1, is characterized in that flexible top board (5), flexible press table (11) adopt the flexible material such as rubber, silicagel pad.
3. the bonding sealing machine of flexible glue according to claim 1 and 2, it is characterized in that the length and width of flexible seaming chuck and flexible push-down head cross section rectangle are measure-alike, rigidity top board (9) and rigidity press table (6) parallelism have requirement.
4. the bonding sealing machine of flexible glue according to claim 1 and 2, is characterized in that two-sided glued membrane that chip involution adopts can select thickness range to be the OCA optics two sided plaster of 25-100 μm according to the width of chip raceway groove, the degree of depth.
5. the bonding sealing machine of flexible glue according to claim 3, is characterized in that two-sided glued membrane that chip involution adopts can select thickness range to be the OCA optics two sided plaster of 25-100 μm according to the width of chip raceway groove, the degree of depth.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510346973.5A CN104948549B (en) | 2015-06-19 | 2015-06-19 | A kind of POCT instant detection chip product quick flexible splicing sealing machine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510346973.5A CN104948549B (en) | 2015-06-19 | 2015-06-19 | A kind of POCT instant detection chip product quick flexible splicing sealing machine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104948549A true CN104948549A (en) | 2015-09-30 |
| CN104948549B CN104948549B (en) | 2016-10-26 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510346973.5A Expired - Fee Related CN104948549B (en) | 2015-06-19 | 2015-06-19 | A kind of POCT instant detection chip product quick flexible splicing sealing machine |
Country Status (1)
| Country | Link |
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| CN (1) | CN104948549B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110469567A (en) * | 2018-05-12 | 2019-11-19 | 宁波方太厨具有限公司 | Water heater glass face shield assembly adhesive tool |
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| CN104377277A (en) * | 2013-08-12 | 2015-02-25 | 人科机械有限公司 | Apparatus and method for fabricating semiconductor chip package with film attached on |
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2015
- 2015-06-19 CN CN201510346973.5A patent/CN104948549B/en not_active Expired - Fee Related
Patent Citations (7)
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|---|---|---|---|---|
| CN103423265A (en) * | 2012-05-24 | 2013-12-04 | 珠海格力电器股份有限公司 | Remote control decorative plate assembly method and device |
| JP2014048018A (en) * | 2012-09-03 | 2014-03-17 | Hoshizaki Electric Co Ltd | Ice making machine |
| EP2784440A1 (en) * | 2013-03-25 | 2014-10-01 | Mitutoyo Corporation | Contour measuring apparatus |
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| CN104948549B (en) | 2016-10-26 |
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