CN104940985A - Medical suture and production method thereof - Google Patents
Medical suture and production method thereof Download PDFInfo
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- CN104940985A CN104940985A CN201510289513.3A CN201510289513A CN104940985A CN 104940985 A CN104940985 A CN 104940985A CN 201510289513 A CN201510289513 A CN 201510289513A CN 104940985 A CN104940985 A CN 104940985A
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Abstract
The invention belongs to the field of medical materials, and concretely relates to a medical suture and a production method thereof. The medical suture comprises, by mass, 80-90 parts of polyglycollide, 5-15 parts of pure natural collagen and 3-8 parts of a coloring agent. The production method of the medical suture comprises the following steps: uniformly mixing polyglycollide with the pure natural collagen, carrying out thread drawing, spraying the coloring agent, carrying out sterilization and disinfection treatment by using medical alcohol, and carrying out vacuum drying packaging. The medical suture has good biocompatibility and degradability, so the medical suture can be absorbed after being stitched to realize no suture removal; the medical suture has large tensile strength and good elasticity; and the production method is simple and easy, and is suitable for industrial production.
Description
Technical field
The invention belongs to field of medical materials, be specifically related to a kind of suture and preparation method thereof.
Background technology
Suture is a kind of thread like material sewed up for body operation, according to material classification, roughly has several large class such as silk thread, catgut, chemosynthesis line, pure-natural collagen stitching thread; Classify according to absorbability, be non-absorbing stitching thread and absorbable suture two kinds.
Requiring suture: can keep enough intensity in wound healing process, also should extend to adapt to wound edema, and is retracted into original length with wound retraction; After wound healing, it again can degraded and absorbed voluntarily, no longer leaves foreign body; Do not produce inflammation; Nonirritant and carcinogenecity; Knot securely can be formed; Easy to make, cheap, can produce etc. in a large number.
Lack that tensile strength is large at present, good springiness and the absorbed suture of degradable.
Summary of the invention
The object of the invention is to provide a kind of suture and preparation method thereof to solve the deficiencies in the prior art, this suture has good biocompatibility, degradability, can be absorbed after sewing up, without the need to take out stitches and tensile strength is large, good springiness.
The technical solution used in the present invention is as follows:
A kind of suture, comprises the following raw material according to mass fraction meter: PGA 80-90 part, pure-natural collagen 5-15 part, coloring agent 3-8 part.
Above-described a kind of suture, comprises the following raw material according to mass fraction meter: PGA 86 parts, pure-natural collagen 12 parts, coloring agent 5 parts.
The preparation method of above-described a kind of suture, comprises the steps:
(1) open plastic high-speed mixer, get PGA and pure-natural collagen, carry out mixed at high speed 30min, the rotating speed of plastic high-speed mixer is 50-60r/min;
(2) mixed raw material is carried out melting and take out line, the diameter of line is 0.02-0.1mm;
(3) showering coloring agent is carried out to the line extracted out, dry;
(4) line coating coloring agent is immersed 30-60min in medical alcohol, carry out sterilizing, last vacuum drying packaging, obtains suture.
In described step (1), the rotating speed of plastic high-speed mixer is 55r/min.
The diameter of described step (2) center line is 0.05mm.
Beneficial effect of the present invention is:
The first, suture of the present invention has good biocompatibility, degradability, can be absorbed, without the need to taking out stitches after sewing up;
The second, suture tensile strength of the present invention is large, good springiness;
3rd, preparation method of the present invention is simple, is suitable for commercial production.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail, the raw material used in the present invention unless otherwise noted, all by commercial acquisition.
Embodiment 1
A kind of suture, comprises the following raw material according to mass fraction meter: PGA 80 parts, pure-natural collagen 5 parts, coloring agent 3 parts.
The preparation method of the suture of the present embodiment, comprises the steps:
(1) open plastic high-speed mixer, get PGA and pure-natural collagen, carry out mixed at high speed 30min, the rotating speed of plastic high-speed mixer is 50/min;
(2) mixed raw material is carried out melting and take out line, the diameter of line is 0.02mm;
(3) showering coloring agent is carried out to the line extracted out, dry;
(4) line coating coloring agent is immersed 30min in medical alcohol, carry out sterilizing, last vacuum drying packaging, obtains described suture.
Embodiment 2
A kind of suture, comprises the following raw material according to mass fraction meter: PGA 82 parts, pure-natural collagen 8 parts, coloring agent 5 parts.
The preparation method of the suture of the present embodiment, comprises the steps:
(1) open plastic high-speed mixer, get PGA and pure-natural collagen, carry out mixed at high speed 30min, the rotating speed of plastic high-speed mixer is 50/min;
(2) mixed raw material is carried out melting and take out line, the diameter of line is 0.04mm;
(3) showering coloring agent is carried out to the line extracted out, dry;
(4) line coating coloring agent is immersed 40min in medical alcohol, carry out sterilizing, last vacuum drying packaging, obtains described suture.
Embodiment 3
A kind of suture, comprises the following raw material according to mass fraction meter: PGA 84 parts, pure-natural collagen 10 parts, coloring agent 6 parts.
The preparation method of the suture of the present embodiment, comprises the steps:
(1) open plastic high-speed mixer, get PGA and pure-natural collagen, carry out mixed at high speed 30min, the rotating speed of plastic high-speed mixer is 55/min;
(2) mixed raw material is carried out melting and take out line, the diameter of line is 0.05mm;
(3) showering coloring agent is carried out to the line extracted out, dry;
(4) line coating coloring agent is immersed 40min in medical alcohol, carry out sterilizing, last vacuum drying packaging, obtains described suture.
Embodiment 4
A kind of suture, comprises the following raw material according to mass fraction meter: PGA 86 parts, pure-natural collagen 12 parts, coloring agent 5 parts.
The preparation method of the suture of the present embodiment, comprises the steps:
(1) open plastic high-speed mixer, get PGA and pure-natural collagen, carry out mixed at high speed 30min, the rotating speed of plastic high-speed mixer is 55/min;
(2) mixed raw material is carried out melting and take out line, the diameter of line is 0.05mm;
(3) showering coloring agent is carried out to the line extracted out, dry;
(4) line coating coloring agent is immersed 50min in medical alcohol, carry out sterilizing, last vacuum drying packaging, obtains described suture.
Embodiment 5
A kind of suture, comprises the following raw material according to mass fraction meter: PGA 90 parts, pure-natural collagen 15 parts, coloring agent 8 parts.
The preparation method of the suture of the present embodiment, comprises the steps:
(1) open plastic high-speed mixer, get PGA and pure-natural collagen, carry out mixed at high speed 30min, the rotating speed of plastic high-speed mixer is 60/min;
(2) mixed raw material is carried out melting and take out line, the diameter of line is 0.1mm;
(3) showering coloring agent is carried out to the line extracted out, dry;
(4) line coating coloring agent is immersed 60min in medical alcohol, carry out sterilizing, last vacuum drying packaging, obtains described suture.
Performance test
Carry out performance test to the embodiment of the present invention 1 ~ 5 products obtained therefrom, result is as following table:
Table 1 properties of product test data
As seen from the above table, the suture in each embodiment all can reach requirement, wherein embodiment 4 products obtained therefrom best results.
Claims (5)
1. a suture, is characterized in that, comprises the following raw material according to mass fraction meter: PGA 80-90 part, pure-natural collagen 5-15 part, coloring agent 3-8 part.
2. a kind of suture according to claim 1, is characterized in that, comprises the following raw material according to mass fraction meter: PGA 86 parts, pure-natural collagen 12 parts, coloring agent 5 parts.
3. the preparation method of a kind of suture according to claim 1, is characterized in that, comprise the steps:
(1) open plastic high-speed mixer, get PGA and pure-natural collagen, carry out mixed at high speed 30min, the rotating speed of plastic high-speed mixer is 50-60r/min;
(2) mixed raw material is carried out melting and take out line, the diameter of line is 0.02-0.1mm;
(3) showering coloring agent is carried out to the line extracted out, dry;
(4) line coating coloring agent is immersed 30-60min in medical alcohol, carry out sterilizing, last vacuum drying packaging, obtains suture.
4. the preparation method of a kind of suture according to claim 3, is characterized in that, in step (1), the rotating speed of plastic high-speed mixer is 55r/min.
5. the preparation method of a kind of suture according to claim 3, is characterized in that, the diameter of step (2) center line is 0.05mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510289513.3A CN104940985A (en) | 2015-05-29 | 2015-05-29 | Medical suture and production method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510289513.3A CN104940985A (en) | 2015-05-29 | 2015-05-29 | Medical suture and production method thereof |
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| CN104940985A true CN104940985A (en) | 2015-09-30 |
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| CN201510289513.3A Pending CN104940985A (en) | 2015-05-29 | 2015-05-29 | Medical suture and production method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105963763A (en) * | 2016-04-20 | 2016-09-28 | 苏州蔻美新材料有限公司 | Medical suture and preparation method thereof |
| CN106725675A (en) * | 2016-12-20 | 2017-05-31 | 马强 | A kind of memorial alloy suture and preparation method for being loaded with growth factor |
| CN107970487A (en) * | 2017-12-26 | 2018-05-01 | 徐州仁和医疗科技有限公司 | A kind of novel medical operation suture |
| WO2020062976A1 (en) * | 2018-09-30 | 2020-04-02 | 温州医科大学 | Degradable surgical suture with biological activity and preparation method therefor |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101033563A (en) * | 2007-03-30 | 2007-09-12 | 东南大学 | High-strength composite nano fiber long yarn and manufacturing method thereof |
| CN101380484A (en) * | 2008-06-30 | 2009-03-11 | 李捷 | Medical operation suture thread |
| CN101406710A (en) * | 2008-11-25 | 2009-04-15 | 同济大学 | Suture thread containing bioactive components and preparation method thereof |
| CN101721739A (en) * | 2008-10-10 | 2010-06-09 | 陈东 | Polymer composite fiber surgical suture line capable of sustaining and controlling release of therapeutic medicaments and preparation method thereof |
| CN104474586A (en) * | 2014-11-25 | 2015-04-01 | 苏州市贝克生物科技有限公司 | Polyglycolic acid medical absorbable suture and preparation method thereof |
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2015
- 2015-05-29 CN CN201510289513.3A patent/CN104940985A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101033563A (en) * | 2007-03-30 | 2007-09-12 | 东南大学 | High-strength composite nano fiber long yarn and manufacturing method thereof |
| CN101380484A (en) * | 2008-06-30 | 2009-03-11 | 李捷 | Medical operation suture thread |
| CN101721739A (en) * | 2008-10-10 | 2010-06-09 | 陈东 | Polymer composite fiber surgical suture line capable of sustaining and controlling release of therapeutic medicaments and preparation method thereof |
| CN101406710A (en) * | 2008-11-25 | 2009-04-15 | 同济大学 | Suture thread containing bioactive components and preparation method thereof |
| CN104474586A (en) * | 2014-11-25 | 2015-04-01 | 苏州市贝克生物科技有限公司 | Polyglycolic acid medical absorbable suture and preparation method thereof |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105963763A (en) * | 2016-04-20 | 2016-09-28 | 苏州蔻美新材料有限公司 | Medical suture and preparation method thereof |
| CN106725675A (en) * | 2016-12-20 | 2017-05-31 | 马强 | A kind of memorial alloy suture and preparation method for being loaded with growth factor |
| CN107970487A (en) * | 2017-12-26 | 2018-05-01 | 徐州仁和医疗科技有限公司 | A kind of novel medical operation suture |
| CN107970487B (en) * | 2017-12-26 | 2021-01-26 | 杭州整形医院有限公司 | Novel medical operation suture line |
| WO2020062976A1 (en) * | 2018-09-30 | 2020-04-02 | 温州医科大学 | Degradable surgical suture with biological activity and preparation method therefor |
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Application publication date: 20150930 |
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