CN104940289A

CN104940289A - Itching-relieving traditional Chinese medicine gel

Info

Publication number: CN104940289A
Application number: CN201510365840.2A
Authority: CN
Inventors: 周建志
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-06-29
Filing date: 2015-06-29
Publication date: 2015-09-30

Abstract

The invention discloses an itching-relieving traditional Chinese medicine gel. The gel is characterized by comprising the following traditional Chinese medicine effective ingredients in percentage by weight: 1-3% of a scutellaria baicalensis extract, 4-6% of a honeysuckle extract, 0.5-2% of a liquorice extract, 1-2% of a divaricate saposhnikovia root extract, 2-3% of lithospermum oil, 2-3% of a radix sophorae flavescentis extract and 0.1-1% of sodium copper chlorophyllin. The itching-relieving gel has the effects of diminishing inflammation and rapidly relieving itching; moreover, by virtue of the good biological adhesiveness of the gel, the itching-relieving and inflammation-diminishing effects of the traditional Chinese medicine extracts can be subjected to slow release and controlled release to help erythema and eczema on the surface of skin to be rapidly relieved in a short time.

Description

A kind of antipruritic Traditional Chinese medicine gel

Technical field

The present invention relates to a kind of gel preparation, particularly a kind of antipruritic Traditional Chinese medicine gel.

Background technology

The latex glop of homogeneous, the suspendible that gel refers to that medicine and the adjuvant that can form gel make or emulsion-type or semi-solid preparation, the general percutaneous of Chinese medicine gel or mucosa delivery, be usually used in the aspects such as anti-inflammatory and antalgic, antiviral, pain relieving at present.Gel, owing to having good bioadhesive, is used in the position such as skin, mucosa, persistent, and have easy to use, experience comfortable, easily wash, the not advantage such as pollution clothes.

Now on the market for antipruritic product based on ointment, and still fewer to the research of this emerging pharmaceutical dosage form of gel.

Summary of the invention

Of the present inventionly provide a kind of antipruritic Traditional Chinese medicine gel, can Quick itch stopping, and easy to use, experience comfortable.

For achieving the above object, technical scheme of the present invention is:

A kind of antipruritic Traditional Chinese medicine gel, is characterized in that: the Effective Component of Chinese Medicine of described gel comprise percentage by weight be 1 ~ 3% Radix Scutellariae extracting solution, 4 ~ 6% Flos Lonicerae extractive solution, 0.5 ~ 2% Radix Glycyrrhizae extract, 1 ~ 2% Radix Saposhnikoviae extracting solution, 2 ~ 3% Oleum Radix Arnebiae (Oleum Radix Lithospermi), 2 ~ 3% Radix Sophorae Flavescentis extractive liquids and 0.1 ~ 1% sodium copper chlorophllin.

The Effective Component of Chinese Medicine of described gel comprise percentage by weight be 2% Radix Scutellariae extracting solution, 5% Flos Lonicerae extractive solution, 1% Radix Glycyrrhizae extract, 1% Radix Saposhnikoviae extracting solution, 2% Oleum Radix Arnebiae (Oleum Radix Lithospermi), 2% Radix Sophorae Flavescentis extractive liquid and 0.8% sodium copper chlorophllin.

Described gel also comprises carbomer 0.3 ~ 0.9%, glycerol 15 ~ 20%, 90% ethanol 5 ~ 8%, propylene glycol 1 ~ 2%, and surplus is purified water.

Described gel adds pH value regulator and PH is adjusted to 6.5 ~ 7.

External use anti pruritic ointment of the present invention, selects Radix Scutellariae, Flos Lonicerae, Radix Glycyrrhizae, Radix Saposhnikoviae, Radix Arnebiae (Radix Lithospermi), Radix Sophorae Flavescentis and sodium copper chlorophllin 6 kinds of natural plant extracts, wherein:

Radix Scutellariae: have heat clearing and damp drying, eliminating fire and detoxication, hemostasis, the effect such as antiabortive.Cure mainly the diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle;

Flos Lonicerae: the good medicine being from ancient times described as heat-clearing and toxic substances removing; Dispelling wind-heat, removing summer-heat blood poison, for various febrile disease, as fever of the body, dermexanthesis, sends out the disease such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, equal Be very effective, is the antipruritic good medicine of miliaria of dispelling;

Radix Glycyrrhizae: lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription.Process use, control weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain generates heat, and consumptive lung disease is coughed, cardiopalmus, infantile convulsion; Raw use, controls laryngopharynx swelling and pain, peptic ulcer, ulcer sores, separates poison of drug and alimentary toxicosis;

Radix Saposhnikoviae: for diseases caused by exogenous pathogenic factor exterior syndrome, rubella pruritus, rheumatic arthralgia, tetanus just, insufficiency of the spleen leading to overabundance of dampness;

Radix Arnebiae (Radix Lithospermi): removing heat from blood, invigorates blood circulation, heat clearing away, removing toxic substances;

Radix Sophorae Flavescentis: for hematodiarrhoea, has blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy;

Sodium copper chlorophllin: the effect with antitoxin, antiulcer, anti-hemolysis, the liver protecting and ALT lowering, inflammation-resisting itch-stopping.

The mutual synergism of above-mentioned natural plant extracts, and be equipped with gentle gel-type vehicle, there is effect of antiinflammatory, Quick itch stopping, and the bioadhesive utilizing gel good, antipruritic, anti-inflammatory effects slow release, the controlled release of Chinese medicine extract can be enable, help the erythema of skin surface, eczema disappear fast at short notice and take off, in addition, change gel also have easy to use, experience comfortable, easily wash, the not advantage such as pollution clothes.

Detailed description of the invention

Embodiment 1

Formula: 10g Radix Scutellariae extracting solution, 45g Flos Lonicerae extractive solution, 20g Radix Glycyrrhizae extract, 10g Radix Saposhnikoviae extracting solution, 30g Oleum Radix Arnebiae (Oleum Radix Lithospermi), 20g Radix Sophorae Flavescentis extractive liquid, 5g sodium copper chlorophllin, 4g carbomer, 150g glycerol, 80g ethanol, 10g propylene glycol, 616g purified water.

Manufacture method: carbomer gradation is added in purified water, limit edged stirs, and places 24h and makes it fully swelling, obtain A after stirring; Oleum Radix Arnebiae (Oleum Radix Lithospermi), sodium copper chlorophllin are added in 90% ethanol, fully mixes, then add glycerol and propylene glycol, obtain B; Radix Scutellariae extracting solution, Flos Lonicerae extractive solution, Radix Glycyrrhizae extract, Radix Saposhnikoviae extracting solution, Radix Sophorae Flavescentis extractive liquid are mixed to get C; By A, B, C tri-mixing, finally add triethanolamine and regulate pH to 6.5 ~ 7, obtain finished gel.

Embodiment 2

Formula: 20g Radix Scutellariae extracting solution, 50g Flos Lonicerae extractive solution, 10g Radix Glycyrrhizae extract, 10g Radix Saposhnikoviae extracting solution, 20g Oleum Radix Arnebiae (Oleum Radix Lithospermi), 20g Radix Sophorae Flavescentis extractive liquid, 8g sodium copper chlorophllin, 4.5g carbomer, 180g glycerol, 50g ethanol, 15g propylene glycol, 612.5g purified water.

Manufacture method: carbomer gradation is added in purified water, limit edged stirs, and places 24h and makes it fully swelling, obtain A after stirring; Oleum Radix Arnebiae (Oleum Radix Lithospermi), sodium copper chlorophllin are added in 90% ethanol, fully mixes, then add glycerol and propylene glycol, obtain B; Radix Scutellariae extracting solution, Flos Lonicerae extractive solution, Radix Glycyrrhizae extract, Radix Saposhnikoviae extracting solution, Radix Sophorae Flavescentis extractive liquid are mixed to get C; By A, B, C tri-mixing, finally add sodium hydroxide and regulate pH to 6.5 ~ 7, obtain finished gel.

Embodiment 3

Formula: 30g Radix Scutellariae extracting solution, 56g Flos Lonicerae extractive solution, 5g Radix Glycyrrhizae extract, 18g Radix Saposhnikoviae extracting solution, 20g Oleum Radix Arnebiae (Oleum Radix Lithospermi), 30g Radix Sophorae Flavescentis extractive liquid, 10g sodium copper chlorophllin, 3.5g carbomer, 200g glycerol, 70g ethanol, 10g propylene glycol, 547.5g purified water.

The extracting method of the Radix Scutellariae extracting solution in above-described embodiment, Flos Lonicerae extractive solution, Radix Glycyrrhizae extract, Radix Saposhnikoviae extracting solution and Radix Sophorae Flavescentis extractive liquid, all after adopting corresponding Chinese medicine to pulverize, drop in the ethanol of 70% of 8 ~ 10 times of weight, soak 4 ~ 5h, ultrasonic extraction 30 ~ 60min, filter, collect filtrate and get final product.

Claims

1. an antipruritic Traditional Chinese medicine gel, is characterized in that: the Effective Component of Chinese Medicine of described gel comprise percentage by weight be 1 ~ 3% Radix Scutellariae extracting solution, 4 ~ 6% Flos Lonicerae extractive solution, 0.5 ~ 2% Radix Glycyrrhizae extract, 1 ~ 2% Radix Saposhnikoviae extracting solution, 2 ~ 3% Oleum Radix Arnebiae (Oleum Radix Lithospermi), 2 ~ 3% Radix Sophorae Flavescentis extractive liquids and 0.1 ~ 1% sodium copper chlorophllin.

2. the antipruritic Traditional Chinese medicine gel of one according to claim 1, is characterized in that:

3. the antipruritic Traditional Chinese medicine gel of one according to claim 1 and 2, is characterized in that:

4. the antipruritic Traditional Chinese medicine gel of one according to claim 3, is characterized in that:

Described gel adds pH value regulator and PH is adjusted to 6.5 ~ 7.