CN104921865A - Self-heating type medical blood pressure lowering hot compress paste and manufacturing method thereof - Google Patents
Self-heating type medical blood pressure lowering hot compress paste and manufacturing method thereof Download PDFInfo
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Abstract
The invention relates to the technical field of medical compress paste, in particular to self-heating type medical blood pressure lowering hot compress paste and a manufacturing method thereof. The self-heating type medical blood pressure lowering hot compress paste comprises a non-woven cloth bag, a heating layer arranged on the non-woven cloth bag and pressure-sensitive tape for fixing the non-woven cloth bag. The heating layer comprises, by weight, 45%-55% of reduced iron powder, 10%-18% of activated carbon, 0.1%-5% of super absorbent polymer, 1%-7% of sodium chloride, 25%-38% of extracts of traditional Chinese medicine, wherein the traditional Chinese medicine in the extracts is composed of cornels, harlequin glorybower leaves, sophora flavescens, jasmines, rhizoma anemarrhenae, fructus forsythia, rabdosia rubescens and rhizoma sparganii. According to the self-heating type medical blood pressure lowering hot compress paste and the manufacturing method, through a mode of combining thermal therapy and the medicine curative effect, the main and collateral channels and blood of the whole body are made to be smooth, the cardiovascular function is conditioned, the blood pressure can be lowered, and headache, dizziness, fullness in head, insomnia and the like caused by high blood pressure are eliminated; the hot compress paste is safe and convenient to use, free of oral administration or injection, free of any toxic and side effect, high in medicine operation speed, good in curative effect and capable of stimulating acupuncture points, dredging collaterals, conditioning the cardiovascular function and lowering the blood pressure effectively.
Description
Technical field
The present invention relates to medical application technical field, be specifically related to a kind of self-heating type blood pressure lowering medical hot compress paste and preparation method thereof.
Background technology
Hypertension is a kind of commonly encountered diseases, and it threatens the life of patient at any time.Current treatment hypertension is all generally treat with oral medicine, injection drug, according to quantity, and will want long-term taking during endo-medicine on time; And injection drug in use patient generally to injection drug can be used in hospital to treat, these all bring inconvenience to patient, and in addition, long hypertension drug easily has side effects after long-term use.
Hot application, also known as heating paste, since the nineties be introduced into from Japan domestic after, through the development in more than 20 years, hot application obtains sizable popularization and application at home, and the reaction principle of hot application accelerates oxidation reaction speed for utilizing galvanic element, is heat energy by converts chemical energy.Hot application is generally by raw material layer, and gelatin layer and non-woven bag form.Raw material layer is placed in non-woven bag, and non-woven bag adopts micro-porous permeable film production.It must have an air-locked outer bag.In use, remove outer bag, allow inner bag and non-woven bag be exposed in air, the oxygen in air enters the inside by ventilated membrane.The time of heat release and temperature are controlled by the oxygen transmission rate of ventilated membrane.If oxygen flow is too fast, heat has just bled off quickly, but also likely scalded skin.If oxygen flow is too slow, just there is no any temperature, so the heating temp of control hot application and fever time are crucial.The curative principle of hot application is as follows: partes corporis humani divides the microcirculqtory system that there is local, for each part of body transports nutrition, discharges rubbish in body.Theory of Chinese medical science is emphasized " general rule not bitterly, pain then obstructed ", and namely meaning attacks when the human body gas cut that often catches cold, and when retardance occurs the microcirculqtory system of local, makes corresponding body both can not get nutrition, cannot discharge refuse again, will produce pain, and then cause pathological changes.And the lasting heat release of hot application can promote that microcirculation in human body enters benign recurrent state, recover normal physiological function, thus eliminate pain, disease therapy.
Hot application is a kind of easy to use, product of having no side effect, there is no at present and occurs hot application and the Chinese medicine of blood pressure lowering can carry out the technology that combines.
Summary of the invention
The object of the invention is to for the deficiencies in the prior art, provide a kind of easy to use, have no side effect, generate heat lasting evenly, self-heating type blood pressure lowering medical hot compress paste that therapeutic effect is good.
To achieve these goals, the present invention adopts following technical scheme: a kind of self-heating type blood pressure lowering medical hot compress paste, comprise Non-woven cloth bag, be arranged at the heating layer of Non-woven cloth bag and the pressure sensitive adhesive tape for fixing Non-woven cloth bag, described heating layer is made up of the raw material of following percentage by weight:
Reduced iron powder 45-55%
Active carbon 10-18%
Hydroscopic high-molecular resin 0.1-5%
Sodium chloride 1-7%
Chinese medicine extraction liquid 25-38%,
Wherein, the Chinese medicine in Chinese medicine extraction liquid is made up of the Fructus Evodiae, Folium et Ramulus Clerodendri Trichotomi, Radix Sophorae Flavescentis, Fructus Gardeniae, the Rhizoma Anemarrhenae, Fructus Forsythiae, Rabdosia rubescens and Rhizoma Sparganii.
Further, described heating layer is made up of the raw material of following percentage by weight:
Reduced iron powder 45-55%
Active carbon 10-18%
Hydroscopic high-molecular resin 0.1-5%
Sodium chloride 1-7%
Chinese medicine extraction liquid 25-38%,
Wherein, Chinese medicine extraction liquid is made up of the Chinese medicine extraction liquid of following percentage by weight:
Fructus Evodiae extracting solution 10-20%
Folium et Ramulus Clerodendri Trichotomi extracting solution 10-20%
Radix Sophorae Flavescentis extractive liquid 10-20%
Gardenia extract 10-20%
Rhizoma Anemarrhenae extracting solution 5-15%
Fructus Forsythiae extracting solution 5-15%
Rabdosia rubescens extracting solution 5-15%
Rhizoma Sparganii extracting solution 5-15%.
Preferably, described heating layer is made up of the raw material of following percentage by weight:
Reduced iron powder 50-55%
Active carbon 14-18%
Hydroscopic high-molecular resin 1-5%
Sodium chloride 3-7%
Chinese medicine extraction liquid 32-38%,
Wherein, Chinese medicine extraction liquid is made up of the Chinese medicine extraction liquid of following percentage by weight:
Fructus Evodiae extracting solution 15-20%
Folium et Ramulus Clerodendri Trichotomi extracting solution 15-20%
Radix Sophorae Flavescentis extractive liquid 15-20%
Gardenia extract 15-20%
Rhizoma Anemarrhenae extracting solution 10-15%
Fructus Forsythiae extracting solution 10-15%
Rabdosia rubescens extracting solution 10-15%
Rhizoma Sparganii extracting solution 10-15%.
Another is preferred, and described heating layer is made up of the raw material of following percentage by weight:
Reduced iron powder 50-55%
Active carbon 10-14%
Hydroscopic high-molecular resin 0.1-1%
Sodium chloride 1-3%
Chinese medicine extraction liquid 32-38%,
Wherein, Chinese medicine extraction liquid is made up of the Chinese medicine extraction liquid of following percentage by weight:
Fructus Evodiae extracting solution 10-15%
Folium et Ramulus Clerodendri Trichotomi extracting solution 10-15%
Radix Sophorae Flavescentis extractive liquid 10-15%
Gardenia extract 10-15%
Rhizoma Anemarrhenae extracting solution 5-10%
Fructus Forsythiae extracting solution 5-10%
Rabdosia rubescens extracting solution 5-10%
Rhizoma Sparganii extracting solution 5-10%.
More preferred, described heating layer is made up of the raw material of following percentage by weight:
Reduced iron powder 50%
Active carbon 14%
Hydroscopic high-molecular resin 1%
Sodium chloride 3%
Chinese medicine extraction liquid 32%,
Wherein, Chinese medicine extraction liquid is made up of the Chinese medicine extraction liquid of following percentage by weight:
Fructus Evodiae extracting solution 15%
Folium et Ramulus Clerodendri Trichotomi extracting solution 15%
Radix Sophorae Flavescentis extractive liquid 15%
Gardenia extract 15%
Rhizoma Anemarrhenae extracting solution 10%
Fructus Forsythiae extracting solution 10%
Rabdosia rubescens extracting solution 10%
Rhizoma Sparganii extracting solution 10%.
Described reduced iron powder is weight ratio is the nanoscale reduced iron powder of 1:5-1:10 and the mixture of micron order reduced iron powder, and the particle diameter of described nanoscale reduced iron powder is 50-200 nanometer, and the particle diameter of described micron order reduced iron powder is 10-100 micron.The present invention utilizes little quality and the high surface energy of nanoscale reduced iron powder, makes nanoscale reduced iron powder be attached to micron order reduced iron powder surface, formed core the composite construction of shell; The nanoscale reduced iron powder not being attached to micron order reduced iron powder will be filled into the various gaps of heating layer, show the various feature performance benefits of nano material.The mode that the present invention adopts the mixture of nanoscale reduced iron powder and micron order reduced iron powder to combine, not only reduces cost, more can make to generate heat in whole hyperthermia process more even.
Described active carbon is weight ratio is the nano level active charcoal of 1:4-1:8 and the mixture of micron order active carbon, and the particle diameter of described nano level active charcoal is 100-300 nanometer, and the particle diameter of described micron order active carbon is 50-150 micron.
The present invention utilizes little quality and the high surface energy of nano level active charcoal, makes nano level active charcoal be attached to micron order activated carbon surface, formed core the composite construction of shell; The nano level active charcoal not being attached to micron order active carbon will be filled into the various gaps of heating layer, show the various feature performance benefits of nano material.The mode that the present invention adopts the mixture of nano level active charcoal and micron order active carbon to combine, not only reduces cost, more can make to generate heat in whole hyperthermia process more even.
Fructus Evodiae extracting solution mixes immersion by 80 order Fructus Evodiae powder and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Folium et Ramulus Clerodendri Trichotomi extracting solution mixes immersion by 80 order Harlequin Glorybower Leaf And Twigs and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Radix Sophorae Flavescentis extractive liquid mixes immersion by 80 order Lightyellow Sophora Roots and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Gardenia extract mixes immersion by 80 order Cape Jasmine Fruits and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Fructus Forsythiae extracting solution mixes immersion by 80 order Weeping Forsythia Capsules and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; By 80 orders, Rabdosia rubescens extracting solution knows that Rabdosia rubescens end and 100 DEG C of hot water mix immersion through 1:5 ratio and obtain with 80 eye mesh screens filtrations after 12 hours; Rhizoma Sparganii extracting solution mixes immersion by 80 order Rhizoma Sparganii powder and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Rhizoma Anemarrhenae extracting solution mixes immersion by 80 order Common Anemarrhena Rhizomes and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours.
A preparation method for self-heating type blood pressure lowering medical hot compress paste, it comprises following preparation process:
Steps A, weighing: the reduced iron powder, active carbon, hydroscopic high-molecular resin, sodium chloride, the Chinese medicine extraction liquid that weigh formula ratio;
Step B, preparation: load weighted for steps A hydroscopic high-molecular resin is joined and fully swellingly in Chinese medicine extraction liquid obtains the swelling body of Chinese medicine hydroscopic high-molecular resin; Being joined by active carbon in the swelling body of Chinese medicine hydroscopic high-molecular resin stirs obtains the first mixture, for subsequent use; Reduced iron powder, sodium chloride are stirred and obtains the second mixture, for subsequent use;
Step C, preparation: the second mixture obtained by step B joins in the first mixture, stirs, obtains heating layer;
Step D, assembling, load Non-woven cloth bag by heating layer, fixing pressure sensitive adhesive tape, the Non-woven cloth bag fixing pressure sensitive adhesive tape loaded sealing bag and preserves, obtain self-heating type blood pressure lowering medical hot compress paste.
Hydroscopic high-molecular resin has hydrophilic group, can absorb moisture in a large number and the swelling synthetic resin that can maintain moisture and not outflow, and can adopt starch grafted acrylate class, graft acrylamide, high substituted degree cross-linked carboxymethyl cellulose, cross-linked carboxymethyl cellulose graft acrylamide, cross-linking type hydroxyethyl-cellulose graft acrylamide polymer.The present invention's preferred cross-linking type hydroxyethyl-cellulose graft acrylamide polymer, the present invention uses hydroscopic high-molecular resin that the present invention both can have been made to become paste, is conducive to again the slow releasing of heat and herbal medicine efficacy, extends fever time and drug effect.
The Fructus Evodiae, sour-puckery flavor, slightly warm in nature, has the function such as invigorating the liver and kidney, arresting seminal emission gas, solid collapse, stomach invigorating tonifying YANG, and the traditional Chinese medical science is commonly used to treat soreness of waist and knee joint, dizzy, tinnitus, seminal emission, frequent micturition, deficiency of the liver cold and heat, incessant sweating due to debility, the heart shake the diseases such as scattered pulse, neurasthenia, menoxenia.The Fructus Evodiae contains the stronger cornin of physiologically active, Herba Setariae Plicatae whip glycoside, Saponin, glycoside of tanning, and has diuresis, blood pressure lowering, protective effect on cancer risk.
Folium et Ramulus Clerodendri Trichotomi, acrid in the mouth, hardship, cold in nature.Liver Channel.There is wind-damp dispelling, effect of blood pressure lowering.Dispelling the wind and dampness pathogens arthralgia pain, hemiplegia, hypertension, migraine, malaria, dysentery, hemorrhoid, carbuncle skin ulcer scabies.
Radix Sophorae Flavescentis, bitter in the mouth, cold in nature.GUIXIN, liver, stomach, large intestine, urinary bladder channel.Heat clearing and damp drying, parasite killing, diuresis.For hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy, external treatment trichomonal vaginitis.
Fructus Gardeniae, heat clearing away, pathogenic fire purging, removing heat from blood.Control calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quench one's thirst, conjunctival congestion, pharyngalgia, spit blood, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprains and swells and ache, and has the effects such as hepatoprotective, function of gallbladder promoting, blood pressure lowering, calmness, hemostasis, detumescence.
The Rhizoma Anemarrhenae, property bitter cold, has nourishing YIN to lower pathogenic fire, moisturizes laxation, the effect of sharp defecation.Gunpowder under genus heat clearing away, cures mainly: epidemic febrile disease, high hot excessive thirst, cough and asthma, cough caused by dryness, constipation, osteopyrexia and fever, restlessness of asrhenia type and insomnia, stranguria with turbid discharge of quenching one's thirst.
Fructus Forsythiae is bitter, cool.Enter the heart, liver, gallbladder meridian.Function cures mainly: heat clearing away, removing toxic substances, eliminating stagnation, detumescence.Control warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.
Rabdosia rubescens, bitter, sweet, be slightly cold, heat clearing away, removing toxic substances, promoting blood circulation and stopping pain, for laryngopharynx swelling and pain, tonsillitis, snake bite and insect sting, rheumatic ostalgia etc.Rabdosia rubescens also have antipyretic, fall dryly to wet one's whistle, blood fat reducing, the effect such as blood pressure lowering.
Rhizoma Sparganii is pungent, bitter, flat.Return liver, spleen channel, removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving.For lump in the abdomen mass in the abdomen, dysmenorrhea, blood stasis amenorrhea, obstruction of qi in the chest and cardialgia, food stagnation distending pain.
Chinese medicine in Chinese medicine extraction liquid of the present invention cooperatively interacts, and plays synergism, has good therapeutic effect to blood pressure lowering.
Join the first mixture from the second mixture that step B is obtained and preserve whole process control within 10min to entering sealing bag.
The present invention selects reduced iron powder and the active carbon of specified particle diameter, cooperatively interacts, and ensures uniformity and the persistency of electrothermal calefactive rate.
Active carbon of the present invention, reduced iron powder, the oxygen in water and sodium chloride and air forms an original battery discharge, and then owing to not having both positive and negative polarity, electronics cannot divide positron-electron to derive, and directly forms short circuit, thus produces heat.
Compared with prior art, beneficial effect is in the present invention: the mode that the present invention is combined by thermotherapy, treatment by Chinese herbs, for having laid a good foundation to hypertensive treatment.Thermotherapy is by having an effect generation thermal energy with the oxygen in air, effectively makes the rapid expansion of local blood capillary, gets through blood vessels blocking, blood circulation promoting, and oxygen content in blood is increased, and body metabolism rate is accelerated, promoting the flow of QI in the collateral by warming the meridian, blood circulation promoting and blood stasis dispelling; Product Spontaneous release thermal energy, promotes the active permeation of medicine, and medicine directly deeply to focus, carries out persistence onset to sufferer place, product the is given full play to effect of thermotherapy and medication.Under the effect of thermotherapy and medication, local blood capillary is expanded rapidly, makes local blood circulation accelerate the increase of oxygen content in blood; organism metabolism rate is also accelerated thereupon; medicine is deep infiltration along with the increasing of thermal energy, and affected part is organized and becomes lax and comfortable gradually, fatigue alleviates; Refuse in human body is accelerated to get rid of, and makes the meridians blood vessels of whole body thereupon unimpeded, regulates cardiovascular function, can reduce blood pressure, and eliminates the symptom such as headache, giddy, feeling of fullness in the head, insomnia that hypertension causes.To sum up, the present invention is safe and convenient to use, need not take orally or inject, without any side effects, instant effect, good effect, can swash cave dredging collateral, regulates cardiovascular function, effectively reduces blood pressure.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated.
embodiment 1.
A kind of self-heating type blood pressure lowering medical hot compress paste, comprise Non-woven cloth bag, be arranged at the heating layer of Non-woven cloth bag and the pressure sensitive adhesive tape for fixing Non-woven cloth bag, described heating layer is made up of the raw material of following percentage by weight:
Reduced iron powder 45%
Active carbon 10%
Hydroscopic high-molecular resin 5%
Sodium chloride 2%
Chinese medicine extraction liquid 38%,
Wherein, Chinese medicine extraction liquid is made up of the Chinese medicine extraction liquid of following percentage by weight:
Fructus Evodiae extracting solution 20%
Folium et Ramulus Clerodendri Trichotomi extracting solution 20%
Radix Sophorae Flavescentis extractive liquid 20%
Gardenia extract 10%
Rhizoma Anemarrhenae extracting solution 5%
Fructus Forsythiae extracting solution 5%
Rabdosia rubescens extracting solution 5%
Rhizoma Sparganii extracting solution 15%.
Described reduced iron powder is weight ratio is the nanoscale reduced iron powder of 1:5 and the mixture of micron order reduced iron powder, and the particle diameter of described nanoscale reduced iron powder is 50 nanometers, and the particle diameter of described micron order reduced iron powder is 10 microns.
Described active carbon is weight ratio is the nano level active charcoal of 1:4 and the mixture of micron order active carbon, and the particle diameter of described nano level active charcoal is 100 nanometers, and the particle diameter of described micron order active carbon is 50 microns.
Fructus Evodiae extracting solution mixes immersion by 80 order Fructus Evodiae powder and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Folium et Ramulus Clerodendri Trichotomi extracting solution mixes immersion by 80 order Harlequin Glorybower Leaf And Twigs and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Radix Sophorae Flavescentis extractive liquid mixes immersion by 80 order Lightyellow Sophora Roots and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Gardenia extract mixes immersion by 80 order Cape Jasmine Fruits and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Fructus Forsythiae extracting solution mixes immersion by 80 order Weeping Forsythia Capsules and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; By 80 orders, Rabdosia rubescens extracting solution knows that Rabdosia rubescens end and 100 DEG C of hot water mix immersion through 1:5 ratio and obtain with 80 eye mesh screens filtrations after 12 hours; Rhizoma Sparganii extracting solution mixes immersion by 80 order Rhizoma Sparganii powder and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Rhizoma Anemarrhenae extracting solution mixes immersion by 80 order Common Anemarrhena Rhizomes and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours.
A preparation method for self-heating type blood pressure lowering medical hot compress paste, it comprises following preparation process:
Steps A, weighing: the reduced iron powder, active carbon, hydroscopic high-molecular resin, sodium chloride, the Chinese medicine extraction liquid that weigh formula ratio;
Step B, preparation: load weighted for steps A hydroscopic high-molecular resin is joined and fully swellingly in Chinese medicine extraction liquid obtains the swelling body of Chinese medicine hydroscopic high-molecular resin; Being joined by active carbon in the swelling body of Chinese medicine hydroscopic high-molecular resin stirs obtains the first mixture, for subsequent use; Reduced iron powder, sodium chloride are stirred and obtains the second mixture, for subsequent use;
Step C, preparation: the second mixture obtained by step B joins in the first mixture, stirs, obtains heating layer;
Step D, assembling, load Non-woven cloth bag by heating layer, fixing pressure sensitive adhesive tape, the Non-woven cloth bag fixing pressure sensitive adhesive tape loaded sealing bag and preserves, obtain self-heating type blood pressure lowering medical hot compress paste.
embodiment 2.
A kind of self-heating type blood pressure lowering medical hot compress paste, comprise Non-woven cloth bag, be arranged at the heating layer of Non-woven cloth bag and the pressure sensitive adhesive tape for fixing Non-woven cloth bag, described heating layer is made up of the raw material of following percentage by weight:
Reduced iron powder 50%
Active carbon 12%
Hydroscopic high-molecular resin 3%
Sodium chloride 5%
Chinese medicine extraction liquid 30%,
Wherein, Chinese medicine extraction liquid is made up of the Chinese medicine extraction liquid of following percentage by weight:
Fructus Evodiae extracting solution 12%
Folium et Ramulus Clerodendri Trichotomi extracting solution 18%
Radix Sophorae Flavescentis extractive liquid 14%
Gardenia extract 16%
Rhizoma Anemarrhenae extracting solution 8%
Fructus Forsythiae extracting solution 12%
Rabdosia rubescens extracting solution 11%
Rhizoma Sparganii extracting solution 9%.
Described reduced iron powder is weight ratio is the nanoscale reduced iron powder of 1:9 and the mixture of micron order reduced iron powder, and the particle diameter of described nanoscale reduced iron powder is 150 nanometers, and the particle diameter of described micron order reduced iron powder is 70 microns.
Described active carbon is weight ratio is the nano level active charcoal of 1:5 and the mixture of micron order active carbon, and the particle diameter of described nano level active charcoal is 220 nanometers, and the particle diameter of described micron order active carbon is 100 microns.
Fructus Evodiae extracting solution mixes immersion by 80 order Fructus Evodiae powder and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Folium et Ramulus Clerodendri Trichotomi extracting solution mixes immersion by 80 order Harlequin Glorybower Leaf And Twigs and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Radix Sophorae Flavescentis extractive liquid mixes immersion by 80 order Lightyellow Sophora Roots and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Gardenia extract mixes immersion by 80 order Cape Jasmine Fruits and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Fructus Forsythiae extracting solution mixes immersion by 80 order Weeping Forsythia Capsules and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; By 80 orders, Rabdosia rubescens extracting solution knows that Rabdosia rubescens end and 100 DEG C of hot water mix immersion through 1:5 ratio and obtain with 80 eye mesh screens filtrations after 12 hours; Rhizoma Sparganii extracting solution mixes immersion by 80 order Rhizoma Sparganii powder and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Rhizoma Anemarrhenae extracting solution mixes immersion by 80 order Common Anemarrhena Rhizomes and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours.
A preparation method for self-heating type blood pressure lowering medical hot compress paste, it comprises following preparation process:
Steps A, weighing: the reduced iron powder, active carbon, hydroscopic high-molecular resin, sodium chloride, the Chinese medicine extraction liquid that weigh formula ratio;
Step B, preparation: load weighted for steps A hydroscopic high-molecular resin is joined and fully swellingly in Chinese medicine extraction liquid obtains the swelling body of Chinese medicine hydroscopic high-molecular resin; Being joined by active carbon in the swelling body of Chinese medicine hydroscopic high-molecular resin stirs obtains the first mixture, for subsequent use; Reduced iron powder, sodium chloride are stirred and obtains the second mixture, for subsequent use;
Step C, preparation: the second mixture obtained by step B joins in the first mixture, stirs, obtains heating layer;
Step D, assembling, load Non-woven cloth bag by heating layer, fixing pressure sensitive adhesive tape, the Non-woven cloth bag fixing pressure sensitive adhesive tape loaded sealing bag and preserves, obtain self-heating type blood pressure lowering medical hot compress paste.
embodiment 3.
A kind of self-heating type blood pressure lowering medical hot compress paste, comprise Non-woven cloth bag, be arranged at the heating layer of Non-woven cloth bag and the pressure sensitive adhesive tape for fixing Non-woven cloth bag, described heating layer is made up of the raw material of following percentage by weight:
Reduced iron powder 50%
Active carbon 14%
Hydroscopic high-molecular resin 1%
Sodium chloride 3%
Chinese medicine extraction liquid 32%,
Wherein, Chinese medicine extraction liquid is made up of the Chinese medicine extraction liquid of following percentage by weight:
Fructus Evodiae extracting solution 15%
Folium et Ramulus Clerodendri Trichotomi extracting solution 15%
Radix Sophorae Flavescentis extractive liquid 15%
Gardenia extract 15%
Rhizoma Anemarrhenae extracting solution 10%
Fructus Forsythiae extracting solution 10%
Rabdosia rubescens extracting solution 10%
Rhizoma Sparganii extracting solution 10%.
Described reduced iron powder is weight ratio is the nanoscale reduced iron powder of 1:8 and the mixture of micron order reduced iron powder, and the particle diameter of described nanoscale reduced iron powder is 100 nanometers, and the particle diameter of described micron order reduced iron powder is 80 microns.
Described active carbon is weight ratio is the nano level active charcoal of 1:6 and the mixture of micron order active carbon, and the particle diameter of described nano level active charcoal is 150 nanometers, and the particle diameter of described micron order active carbon is 120 microns.
Fructus Evodiae extracting solution mixes immersion by 80 order Fructus Evodiae powder and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Folium et Ramulus Clerodendri Trichotomi extracting solution mixes immersion by 80 order Harlequin Glorybower Leaf And Twigs and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Radix Sophorae Flavescentis extractive liquid mixes immersion by 80 order Lightyellow Sophora Roots and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Gardenia extract mixes immersion by 80 order Cape Jasmine Fruits and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Fructus Forsythiae extracting solution mixes immersion by 80 order Weeping Forsythia Capsules and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; By 80 orders, Rabdosia rubescens extracting solution knows that Rabdosia rubescens end and 100 DEG C of hot water mix immersion through 1:5 ratio and obtain with 80 eye mesh screens filtrations after 12 hours; Rhizoma Sparganii extracting solution mixes immersion by 80 order Rhizoma Sparganii powder and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Rhizoma Anemarrhenae extracting solution mixes immersion by 80 order Common Anemarrhena Rhizomes and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours.
A preparation method for self-heating type blood pressure lowering medical hot compress paste, it comprises following preparation process:
Steps A, weighing: the reduced iron powder, active carbon, hydroscopic high-molecular resin, sodium chloride, the Chinese medicine extraction liquid that weigh formula ratio;
Step B, preparation: load weighted for steps A hydroscopic high-molecular resin is joined and fully swellingly in Chinese medicine extraction liquid obtains the swelling body of Chinese medicine hydroscopic high-molecular resin; Being joined by active carbon in the swelling body of Chinese medicine hydroscopic high-molecular resin stirs obtains the first mixture, for subsequent use; Reduced iron powder, sodium chloride are stirred and obtains the second mixture, for subsequent use;
Step C, preparation: the second mixture obtained by step B joins in the first mixture, stirs, obtains heating layer;
Step D, assembling, load Non-woven cloth bag by heating layer, fixing pressure sensitive adhesive tape, the Non-woven cloth bag fixing pressure sensitive adhesive tape loaded sealing bag and preserves, obtain self-heating type blood pressure lowering medical hot compress paste.
embodiment 4.
A kind of self-heating type blood pressure lowering medical hot compress paste, comprise Non-woven cloth bag, be arranged at the heating layer of Non-woven cloth bag and the pressure sensitive adhesive tape for fixing Non-woven cloth bag, described heating layer is made up of the raw material of following percentage by weight:
Reduced iron powder 55%
Active carbon 15%
Hydroscopic high-molecular resin 1%
Sodium chloride 4%
Chinese medicine extraction liquid 25%,
Wherein, Chinese medicine extraction liquid is made up of the Chinese medicine extraction liquid of following percentage by weight:
Fructus Evodiae extracting solution 10%
Folium et Ramulus Clerodendri Trichotomi extracting solution 10%
Radix Sophorae Flavescentis extractive liquid 10%
Gardenia extract 20%
Rhizoma Anemarrhenae extracting solution 15%
Fructus Forsythiae extracting solution 15%
Rabdosia rubescens extracting solution 15%
Rhizoma Sparganii extracting solution 5%.
Described reduced iron powder is weight ratio is the nanoscale reduced iron powder of 1:10 and the mixture of micron order reduced iron powder, and the particle diameter of described nanoscale reduced iron powder is 200 nanometers, and the particle diameter of described micron order reduced iron powder is 100 microns.
Described active carbon is weight ratio is the nano level active charcoal of 1:8 and the mixture of micron order active carbon, and the particle diameter of described nano level active charcoal is 300 nanometers, and the particle diameter of described micron order active carbon is 150 microns.
Fructus Evodiae extracting solution mixes immersion by 80 order Fructus Evodiae powder and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Folium et Ramulus Clerodendri Trichotomi extracting solution mixes immersion by 80 order Harlequin Glorybower Leaf And Twigs and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Radix Sophorae Flavescentis extractive liquid mixes immersion by 80 order Lightyellow Sophora Roots and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Gardenia extract mixes immersion by 80 order Cape Jasmine Fruits and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Fructus Forsythiae extracting solution mixes immersion by 80 order Weeping Forsythia Capsules and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; By 80 orders, Rabdosia rubescens extracting solution knows that Rabdosia rubescens end and 100 DEG C of hot water mix immersion through 1:5 ratio and obtain with 80 eye mesh screens filtrations after 12 hours; Rhizoma Sparganii extracting solution mixes immersion by 80 order Rhizoma Sparganii powder and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Rhizoma Anemarrhenae extracting solution mixes immersion by 80 order Common Anemarrhena Rhizomes and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours.
A preparation method for self-heating type blood pressure lowering medical hot compress paste, it comprises following preparation process:
Steps A, weighing: the reduced iron powder, active carbon, hydroscopic high-molecular resin, sodium chloride, the Chinese medicine extraction liquid that weigh formula ratio;
Step B, preparation: load weighted for steps A hydroscopic high-molecular resin is joined and fully swellingly in Chinese medicine extraction liquid obtains the swelling body of Chinese medicine hydroscopic high-molecular resin; Being joined by active carbon in the swelling body of Chinese medicine hydroscopic high-molecular resin stirs obtains the first mixture, for subsequent use; Reduced iron powder, sodium chloride are stirred and obtains the second mixture, for subsequent use;
Step C, preparation: the second mixture obtained by step B joins in the first mixture, stirs, obtains heating layer;
Step D, assembling, load Non-woven cloth bag by heating layer, fixing pressure sensitive adhesive tape, the Non-woven cloth bag fixing pressure sensitive adhesive tape loaded sealing bag and preserves, obtain self-heating type blood pressure lowering medical hot compress paste.
Pertinent clinical data is as follows: in 160 routine cases, oldest 60 years old, minimum 30 years old, is divided into four groups at random, often organizes 40 examples.Four groups of cases through statistical analysis no significant difference, have comparability in age etc.All cases, all with reference to Western medicine diagnose standard, are made a definite diagnosis according to the Diagnosing Hypertension of WHO revision in 1999 and " new Chinese medicine guideline of clinical investigations " criterion of therapeutical effect of grade scale and syndrome of upper hyperactivity of liver yang CM syndrome differentiation criterion and Ministry of Public Health issue in 1993.
Diagnostic criteria:
Ideal bp: systolic pressure < 120mmHg, diastolic pressure < 80mmHg;
Normal arterial pressure: systolic pressure < 130mmHg, diastolic pressure < 85mmHg;
Normal high limit: systolic pressure 130 ~ 139mmHg, diastolic pressure 85 ~ 89mmHg;
1 grade of hypertension: systolic pressure 140 ~ 159mmHg, diastolic pressure 90 ~ 99mmHg (subgroup: borderline hypertension, systolic pressure 140 ~ 149mmHg, diastolic pressure 90 ~ 94mmHg);
2 grades of hypertension: systolic pressure 160 ~ 179mmHg, diastolic pressure 100 ~ 109mmHg.
Therapeutic Method: four groups of each 40 examples, accept respectively embodiment 1, embodiment 2, embodiment 3, embodiment 4 hot application carry out clinical treatment, external (stance) is affixed on umbilical part 36 hours and changes once, and manifold card is taken a day off for six days.It within 30 days, is a course for the treatment of.
Criterion of therapeutical effect: effective: diastolic pressure decline > 10mmHg is also down to normal or decline more than > 20mmHg, and dizzy, headache syndromes disappears substantially, and other symptoms obviously alleviate; Effective: though diastolic pressure decline does not reach 10mmHg be down to the normal or 10 ~ 19mmHg that declines, dizzy, headache syndromes substantially disappears, but has dizziness, headache time excited, and pressure ascensional range is no more than 150/95mmHg; Invalid: not reach above-mentioned curative effect person.
After four groups of case treatments, comparitive study statistical result is as follows:
。
Clinical verification shows simultaneously, and this product uses environmental protection preparation, self-heating in atmosphere, and heating power is lasting, and heating temp is 46-58 degree Celsius, and fever time is 8-36 hour, and curative effect is longer.
Mrs Li, 58 years old, takes depressor throughout the year, existing 15 years, hypertension high pressure 160-90 or 152-100 before medication, and after using hot application 15 of the present invention to paste, blood pressure remains on 120-80.
Mr. Liu, 35 years old, hypertension, high pressure 180, low pressure 100, use hot application 10 of the present invention to paste, blood pressure was down to 130-80, stops eating depressor, does not take depressor so far.
Finally should be noted that; above embodiment is only in order to illustrate technical scheme of the present invention; but not limiting the scope of the invention; although done to explain to the present invention with reference to preferred embodiment; those of ordinary skill in the art is to be understood that; can modify to technical scheme of the present invention or equivalent replacement, and not depart from essence and the scope of technical solution of the present invention.
Claims (9)
1. a self-heating type blood pressure lowering medical hot compress paste, comprises Non-woven cloth bag, is arranged at the heating layer of Non-woven cloth bag and the pressure sensitive adhesive tape for fixing Non-woven cloth bag, it is characterized in that:
Described heating layer is made up of the raw material of following percentage by weight:
Reduced iron powder 45-55%
Active carbon 10-18%
Hydroscopic high-molecular resin 0.1-5%
Sodium chloride 1-7%
Chinese medicine extraction liquid 25-38%,
Wherein, the Chinese medicine in Chinese medicine extraction liquid is made up of the Fructus Evodiae, Folium et Ramulus Clerodendri Trichotomi, Radix Sophorae Flavescentis, Fructus Gardeniae, the Rhizoma Anemarrhenae, Fructus Forsythiae, Rabdosia rubescens and Rhizoma Sparganii.
2. a kind of self-heating type blood pressure lowering medical hot compress paste according to claim 1, is characterized in that: described heating layer is made up of the raw material of following percentage by weight:
Reduced iron powder 45-55%
Active carbon 10-18%
Hydroscopic high-molecular resin 0.1-5%
Sodium chloride 1-7%
Chinese medicine extraction liquid 25-38%,
Wherein, Chinese medicine extraction liquid is made up of the Chinese medicine extraction liquid of following percentage by weight:
Fructus Evodiae extracting solution 10-20%
Folium et Ramulus Clerodendri Trichotomi extracting solution 10-20%
Radix Sophorae Flavescentis extractive liquid 10-20%
Gardenia extract 10-20%
Rhizoma Anemarrhenae extracting solution 5-15%
Fructus Forsythiae extracting solution 5-15%
Rabdosia rubescens extracting solution 5-15%
Rhizoma Sparganii extracting solution 5-15%.
3. a kind of self-heating type blood pressure lowering medical hot compress paste according to claim 1, is characterized in that: described heating layer is made up of the raw material of following percentage by weight:
Reduced iron powder 50-55%
Active carbon 14-18%
Hydroscopic high-molecular resin 1-5%
Sodium chloride 3-7%
Chinese medicine extraction liquid 32-38%,
Wherein, Chinese medicine extraction liquid is made up of the Chinese medicine extraction liquid of following percentage by weight:
Fructus Evodiae extracting solution 15-20%
Folium et Ramulus Clerodendri Trichotomi extracting solution 15-20%
Radix Sophorae Flavescentis extractive liquid 15-20%
Gardenia extract 15-20%
Rhizoma Anemarrhenae extracting solution 10-15%
Fructus Forsythiae extracting solution 10-15%
Rabdosia rubescens extracting solution 10-15%
Rhizoma Sparganii extracting solution 10-15%.
4. a kind of self-heating type blood pressure lowering medical hot compress paste according to claim 1, is characterized in that: described heating layer is made up of the raw material of following percentage by weight:
Reduced iron powder 50-55%
Active carbon 10-14%
Hydroscopic high-molecular resin 0.1-1%
Sodium chloride 1-3%
Chinese medicine extraction liquid 32-38%,
Wherein, Chinese medicine extraction liquid is made up of the Chinese medicine extraction liquid of following percentage by weight:
Fructus Evodiae extracting solution 10-15%
Folium et Ramulus Clerodendri Trichotomi extracting solution 10-15%
Radix Sophorae Flavescentis extractive liquid 10-15%
Gardenia extract 10-15%
Rhizoma Anemarrhenae extracting solution 5-10%
Fructus Forsythiae extracting solution 5-10%
Rabdosia rubescens extracting solution 5-10%
Rhizoma Sparganii extracting solution 5-10%.
5. a kind of self-heating type blood pressure lowering medical hot compress paste according to claim 1, is characterized in that: described heating layer is made up of the raw material of following percentage by weight:
Reduced iron powder 50%
Active carbon 14%
Hydroscopic high-molecular resin 1%
Sodium chloride 3%
Chinese medicine extraction liquid 32%,
Wherein, Chinese medicine extraction liquid is made up of the Chinese medicine extraction liquid of following percentage by weight:
Fructus Evodiae extracting solution 15%
Folium et Ramulus Clerodendri Trichotomi extracting solution 15%
Radix Sophorae Flavescentis extractive liquid 15%
Gardenia extract 15%
Rhizoma Anemarrhenae extracting solution 10%
Fructus Forsythiae extracting solution 10%
Rabdosia rubescens extracting solution 10%
Rhizoma Sparganii extracting solution 10%.
6. a kind of self-heating type blood pressure lowering medical hot compress paste according to claim 1, it is characterized in that: described reduced iron powder is weight ratio is the nanoscale reduced iron powder of 1:5-1:10 and the mixture of micron order reduced iron powder, the particle diameter of described nanoscale reduced iron powder is 50-200 nanometer, and the particle diameter of described micron order reduced iron powder is 10-100 micron.
7. a kind of self-heating type blood pressure lowering medical hot compress paste according to claim 1, it is characterized in that: described active carbon is weight ratio is the nano level active charcoal of 1:4-1:8 and the mixture of micron order active carbon, the particle diameter of described nano level active charcoal is 100-300 nanometer, and the particle diameter of described micron order active carbon is 50-150 micron.
8. a kind of self-heating type blood pressure lowering medical hot compress paste according to claim 2, is characterized in that: Fructus Evodiae extracting solution mixes immersion by Fructus Evodiae powder and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Folium et Ramulus Clerodendri Trichotomi extracting solution mixes immersion by Harlequin Glorybower Leaf And Twig and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Radix Sophorae Flavescentis extractive liquid mixes immersion by Lightyellow Sophora Root and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Gardenia extract mixes immersion by Cape Jasmine Fruit and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Fructus Forsythiae extracting solution mixes immersion by Weeping Forsythia Capsule and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Rabdosia rubescens extracting solution is by knowing that Rabdosia rubescens end and 100 DEG C of hot water mix immersion through 1:5 ratio and obtain with 80 eye mesh screens filtrations after 12 hours; Rhizoma Sparganii extracting solution mixes immersion by Rhizoma Sparganii powder and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours; Rhizoma Anemarrhenae extracting solution mixes immersion by Common Anemarrhena Rhizome and 100 DEG C of hot water through 1:5 ratio and obtains with 80 eye mesh screens filtrations after 12 hours.
9. the preparation method of a kind of self-heating type blood pressure lowering medical hot compress paste described in any one of claim 1-8, is characterized in that: it comprises following preparation process:
Steps A, weighing: the reduced iron powder, active carbon, hydroscopic high-molecular resin, sodium chloride, the Chinese medicine extraction liquid that weigh formula ratio;
Step B, preparation: load weighted for steps A hydroscopic high-molecular resin is joined and fully swellingly in Chinese medicine extraction liquid obtains the swelling body of Chinese medicine hydroscopic high-molecular resin; Being joined by active carbon in the swelling body of Chinese medicine hydroscopic high-molecular resin stirs obtains the first mixture, for subsequent use; Reduced iron powder, sodium chloride are stirred and obtains the second mixture, for subsequent use;
Step C, preparation: the second mixture obtained by step B joins in the first mixture, stirs, obtains heating layer;
Step D, assembling, load Non-woven cloth bag by heating layer, fixing pressure sensitive adhesive tape, the Non-woven cloth bag fixing pressure sensitive adhesive tape loaded sealing bag and preserves, obtain self-heating type blood pressure lowering medical hot compress paste.
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| CN1034137A (en) * | 1988-11-17 | 1989-07-26 | 姜锡洲 | A kind of preparation method of warm application compress |
| CN1733117A (en) * | 2005-07-29 | 2006-02-15 | 江祖怡 | Process for preparing plaster to treat hypertension |
| CN102499808A (en) * | 2011-09-28 | 2012-06-20 | 崔立帮 | Fragrant warming plaster and preparation method thereof |
| CN102977861A (en) * | 2012-11-12 | 2013-03-20 | 无锡尚瑞德医疗器械有限公司 | Self-heating hot compress material composition, self-heating hot bag, and preparation method thereof |
| CN103300962A (en) * | 2013-05-31 | 2013-09-18 | 天津富勤科技有限公司 | Elastic hot compress medical patch |
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2015
- 2015-06-19 CN CN201510343260.3A patent/CN104921865A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1034137A (en) * | 1988-11-17 | 1989-07-26 | 姜锡洲 | A kind of preparation method of warm application compress |
| CN1733117A (en) * | 2005-07-29 | 2006-02-15 | 江祖怡 | Process for preparing plaster to treat hypertension |
| CN102499808A (en) * | 2011-09-28 | 2012-06-20 | 崔立帮 | Fragrant warming plaster and preparation method thereof |
| CN102977861A (en) * | 2012-11-12 | 2013-03-20 | 无锡尚瑞德医疗器械有限公司 | Self-heating hot compress material composition, self-heating hot bag, and preparation method thereof |
| CN103300962A (en) * | 2013-05-31 | 2013-09-18 | 天津富勤科技有限公司 | Elastic hot compress medical patch |
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