CN104917471A - Acquisition and amplification circuit for physiological signals - Google Patents

Acquisition and amplification circuit for physiological signals Download PDF

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Publication number
CN104917471A
CN104917471A CN201510376590.2A CN201510376590A CN104917471A CN 104917471 A CN104917471 A CN 104917471A CN 201510376590 A CN201510376590 A CN 201510376590A CN 104917471 A CN104917471 A CN 104917471A
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operational amplifier
resistance
output
circuit
input
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CN104917471B (en
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李飞腾
陈志坚
徐银
王潇潇
刘东启
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Zhejiang University ZJU
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Zhejiang University ZJU
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Abstract

Provided is an acquisition and amplification circuit for physiological signals. The acquisition and amplification circuit comprises a differential input and primary amplification circuit, a filter circuit and a secondary amplification and voltage lifting circuit. The differential input and primary amplification circuit is connected to inputted physiological signals and used for sampling and primary amplification of physiological signals. The filter circuit is connected to an output end of the differential input and primary amplification circuit. An output signal of the differential input and primary amplification circuit is subjected to band-pass filtering and 50 Hz power frequency notch. The secondary amplification and voltage lifting circuit is connected to an output end of the filter circuit. Signals subjected to filtering operation are amplified again and the minimum value of amplified signals is lifted up above the zero volt. The differential input and primary amplification circuit comprises a differential input sub circuit, a resistance-capacitance filtration sub circuit, a first-stage amplification sub circuit and a reference potential feedback sub circuit. The invention provides the acquisition and amplification circuit for physiological signals which effectively protects the body with higher accuracy and fine accuracy.

Description

A kind of physiological signal collection amplifying circuit
Technical field
The present invention relates to medical measurement Instrument technology field, particularly relate to the physiological signal collection such as myoelectricity, electrocardio amplifying circuit.
Background technology
Existing physiological signal collection amplifying circuit comprises: Acquisition Circuit, for physiological signal collection is entered circuit; Filter circuit, carries out filtering process for physiological signal Acquisition Circuit collected by physiological signal characteristic; Amplifying circuit, for being amplified by the physiological signal after filtering, is convenient to display.The technological deficiency existed is: (1) input impedance is low, and the isolation effect of skin and circuit is bad; (2) common-mode rejection ratio is not high; Filter circuit exponent number is lower, or adopts passive filtering, and filter effect is poor; The problems referred to above cause current Acquisition Circuit inadequate to the protection of health, and sampling precision is not high, and cannot be used for medical science and detect, experimental data is to accurately judging that the reference significance of health is little.
Summary of the invention
In order to overcome existing physiological signal collection amplify mode to bodily protection not, precision is lower, accuracy is poor deficiency, the invention provides a kind of effectively to bodily protection, precision is higher, accuracy is good physiological signal collection amplifying circuit.
The technical solution adopted for the present invention to solve the technical problems is:
A kind of physiological signal collection amplifying circuit, comprising:
Differential Input and elementary amplifying circuit, be connected to the physiological signal of input, samples and amplify for the first time physiological signal;
Filter circuit, is connected to the output of Differential Input and elementary amplifying circuit, carries out bandpass filtering and 50Hz notch filter to the output signal of Differential Input and elementary amplifying circuit;
Secondary amplifies and voltage lifting circuit, is connected to the output of filter circuit, again amplifies and the minimum value signal after amplifying is raised to more than zero volt to the signal after filtering;
Wherein, described Differential Input and elementary amplifying circuit comprise
Difference high resistant input electronic circuit, comprises positive input, benchmark, negative input three inputs, is connected to the diverse location of human body surface, and adopt two-way BiFET operational amplifier to carry out the process of difference high resistant to the physiological signal of positive input, negative input respectively;
Capacitance-resistance filter electronic circuit, is connected to the output of difference high resistant input electronic circuit, carries out the identical capacitance-resistance filter of filtering characteristic respectively to the output of two-way BiFET operational amplifier;
One-level amplifies electronic circuit, be connected to the output of capacitance-resistance filter electronic circuit, adopt instrument amplifier to export the two-way of capacitance-resistance filter electronic circuit and carry out differential amplification and the filter circuit of output supply rear class that will export as Differential Input and elementary amplifying circuit, one-level is amplified electronic circuit and is produced reference potential and export simultaneously;
Reference potential feedback sub-circuit, be connected to the reference potential output that one-level amplifies electronic circuit, and adopt operational amplifier carry out active power filtering and amplify process, produce reference potential and export, and by reference potential output feedack to benchmark input end, feedover to capacitance-resistance filter electronic circuit simultaneously.
Further, described filter circuit comprises:
Bandpass filtering electronic circuit, is connected to the output of Differential Input and elementary amplifying circuit, carries out bandpass filtering to input signal;
Notch filter electronic circuit, is connected to the output of bandpass filtering electronic circuit, carries out 50Hz notch filter to the signal of input.
Further again, described difference high resistant input electronic circuit comprises BiFET operational amplifier U1 and U2, resistance R6, R7, R8, electric capacity CC1, CC2, CS1, CS2, the positive input terminal of difference high resistant input electronic circuit is connected with BiFET operational amplifier U1 positive input, BiFET operational amplifier U1 negative input road is connected with BiFET operational amplifier U1 output by resistance R6, another road is connected with one end of resistance R7, difference high resistant input electronic circuit negative input end is connected with BiFET operational amplifier U2 positive input, BiFET operational amplifier U2 negative input road is connected with BiFET operational amplifier U2 output by resistance R8, another road is connected with the other end of resistance R7, the output pin of BiFET operational amplifier U1 is connected with the input CR+ of capacitance-resistance filter electronic circuit, the output pin of BiFET operational amplifier U2 is connected with the input CR-of capacitance-resistance filter electronic circuit.
Described capacitance-resistance filter electronic circuit comprises electric capacity C2, C3, resistance R9, R10, capacitance-resistance filter electronic circuit input CR+ is connected with resistance R9 one end through electric capacity C2 mono-tunnel, the input OP1+ that another road and one-level amplify electronic circuit is connected, capacitance-resistance filter electronic circuit input CR-is connected with resistance R10 one end through electric capacity C3 mono-tunnel, the input OP1-that another road and one-level amplify electronic circuit is connected, the resistance R9 other end is connected with the R10 other end, and this tie point is connected with the output of reference potential feedback sub-circuit again.
Described one-level is amplified electronic circuit and is comprised instrument amplifier U4, resistance R1, R2, R3, electric capacity CC3, CS3, wherein resistance R3 two gain control making pin accessing instrument amplifier U4 in parallel with resistance R1 after connecting with resistance R2, the output OP1_OUT of instrument amplifier amplifies the output of electronic circuit as one-level and is connected with the input of filter circuit, and the intermediate point of resistance R2 with R3 is connected with the input of reference potential feedback sub-circuit.
Reference potential feedback sub-circuit comprises operational amplifier U3, resistance R4, R5, electric capacity C1, CC4, CS4, wherein input one tunnel of reference potential feedback sub-circuit is connected with operational amplifier U3 negative input end, second tunnel is connected with resistance R5 one end, the other end of resistance R5 is connected to the output of operational amplifier U3, 3rd tunnel is connected to the output of operational amplifier U3 through resistance R4 and electric capacity C1, the positive input terminal ground connection of operational amplifier, output one tunnel of operational amplifier U3 is connected to the reference edge of Differential Input and elementary amplifying circuit, another road is connected to the intermediate point of R9 and R10 in capacitance-resistance filter electronic circuit.
Described bandpass filtering electronic circuit comprises operational amplifier U5A and U5B, resistance R11, R12, R13, R14, R15, electric capacity C4, C5, C6, C7, C8, CC5, CS5, wherein the output of Differential Input and elementary amplifying circuit leads up to resistance R11 ground connection by electric capacity C4, second tunnel is connected with the negative input end of operational amplifier U5A by C5, 3rd tunnel is connected with the output of operational amplifier U5A by electric capacity C6, resistance R12 mono-termination operational amplifier U5A negative input end, the other end is connected with the output of operational amplifier U5A, the output of described operational amplifier U5A leads up to C7 ground connection by R13, second tunnel is connected with the negative input end of operational amplifier U5B by resistance R14, 3rd tunnel is connected with the output of operational amplifier U5B by resistance R15, electric capacity C8 mono-termination operational amplifier U5B negative input end, the other end is connected with the output of operational amplifier U5B, the output of U5B and the output BP_OUT of bandpass filtering electronic circuit, positive supply pin one tunnel of operational amplifier U5 meets 9V positive supply VCC, separately lead up to electric capacity CC5 ground connection, negative supply pin one tunnel of operational amplifier U5 meets-9V negative supply VSS, separately lead up to electric capacity CS5 ground connection.
Described notch filter electronic circuit comprises two operational amplifier U5C and U5D, resistance R23, R24, R25, RW2, RW3, RW4, RW1, R19, electric capacity C9, C10, C11, C12, described notch filter electronic circuit input one tunnel series resistance R23 according to the order of sequence, RW2, RW3, then R24 is connected to operational amplifier U5D positive input terminal, another road series capacitance C9 according to the order of sequence, then C10 is connected to operational amplifier U5D positive input terminal, and electric capacity C9 is connected RW4 according to the order of sequence with C10 intermediate point, R25, then C11 is connected to the intermediate point of resistance RW2 and RW3, C12 and C11 is in parallel, the negative input end of operational amplifier U5D is connected with the output of operational amplifier U5D, operational amplifier U5D output contact resistance RW1 mono-tunnel concatenation operation amplifier U5C positive input terminal, separately lead up to resistance R19 ground connection, the negative input end of operational amplifier U5C is connected with the output of operational amplifier U5C, the tie point that the output of operational amplifier U5C is connected to resistance R25 and electric capacity C11 is formed and feeds back, and the output of operational amplifier U5D and the output Trap_OUT of notch filter electronic circuit amplify with secondary and be connected with voltage lifting circuit input end.
Described secondary amplifies and voltage lifting circuit comprises two operational amplifier U6A and U6B, reference power supply U10, resistance R20, R21, RW5, R27, R28, electric capacity C13, CC6, CS6, CC7, described secondary amplification is connected with operational amplifier U6A negative input end by resistance R20 mono-tunnel with voltage lifting circuit input end, another road R21 and RW5 that connects according to the order of sequence is connected to the output of operational amplifier U6A, the positive input terminal ground connection of operational amplifier U6A, the output of operational amplifier U6A is connected with operational amplifier U6B positive input by resistance R27, reference power supply U10 output is leaded up to resistance R28 and is connected to operational amplifier U6B positive input terminal, separately lead up to electric capacity C13 ground connection, the negative input end of operational amplifier U6B is connected with the output of operational amplifier U6B, positive supply pin one tunnel of operational amplifier U6A and U6B meets 9V positive supply VCC, separately lead up to electric capacity CC6 ground connection, negative supply pin one tunnel of operational amplifier U6A and U6B meets-9V negative supply VSS, separately lead up to electric capacity CS6 ground connection, power pins one tunnel of reference power supply U10 meets 9V positive supply VCC, separately lead up to electric capacity CC7 ground connection, the enable pin of reference power supply U10 meets positive supply VCC, the output of operational amplifier U6B and described secondary amplify the output with voltage lifting circuit, also be the output PS_OUT of described physiological signal collection amplifying circuit.
Technical conceive of the present invention is: adopt BiFET operational amplifier to improve input impedance, adopts the method for Differential Input and reference voltage twice feedback to improve common-mode rejection ratio, and the method adopting fourth-order band-pass filtering to add notch filter improves filter effect.Compare the problem that current portability physiological signal collection circuit precision is on the low side, the present invention is in maintenance low cost, and small size, while the advantages such as high portability, improves signals collecting precision, can carry out medical assistance detection.
Beneficial effect of the present invention is mainly manifested in: by bio-signal acquisition portable devices while guarantee precision, make basic bio-signal acquisition depend on hospital, and testing cost reduced.
Accompanying drawing explanation
Fig. 1 is schematic diagram block diagram of the present invention;
Fig. 2 is Differential Input and elementary amplifying circuit schematic diagram block diagram;
Fig. 3 is filter circuit schematic diagram block diagram;
Fig. 4 is that secondary amplifies and voltage lifting circuit theory diagrams;
Fig. 5 is Differential Input and elementary amplifying circuit difference high resistant input electronic circuit schematic diagram;
Fig. 6 is Differential Input and elementary amplifying circuit capacitance-resistance filter electronic circuit schematic diagram;
Fig. 7 is that Differential Input and elementary amplifying circuit one-level amplify electronic circuit schematic diagram;
Fig. 8 is Differential Input and elementary amplifying circuit reference potential feedback sub-circuit schematic diagram;
Fig. 9 is filter circuit bandpass filtering electronic circuit schematic diagram;
Figure 10 is filter circuit notch filter electronic circuit schematic diagram.
Embodiment
Below in conjunction with accompanying drawing, the invention will be further described.
With reference to Fig. 1 ~ Figure 10, a kind of physiological signal collection amplifying circuit, comprising:
Differential Input and elementary amplifying circuit, be connected to the physiological signal of input, samples and amplify for the first time physiological signal;
Filter circuit, is connected to the output of Differential Input and elementary amplifying circuit, carries out bandpass filtering and 50Hz notch filter to the output signal of Differential Input and elementary amplifying circuit;
Secondary amplifies and voltage lifting circuit, is connected to the output of filter circuit, again amplifies and the minimum value signal after amplifying is raised to more than zero volt to the signal after filtering.
Further, described Differential Input and elementary amplifying circuit comprise four electronic circuits:
Difference high resistant input electronic circuit, containing positive input, benchmark, negative input three inputs, is connected to the diverse location of human body surface, and adopts two-way BiFET operational amplifier to carry out the process of difference high resistant to the physiological signal of positive input, negative input respectively;
Capacitance-resistance filter electronic circuit, is connected to the output of difference high resistant input electronic circuit, carries out the identical capacitance-resistance filter of filtering characteristic respectively to the output of two-way BiFET operational amplifier;
One-level amplifies electronic circuit, be connected to the output of capacitance-resistance filter electronic circuit, adopt instrument amplifier to export the two-way of capacitance-resistance filter electronic circuit and carry out differential amplification and the filter circuit of output supply rear class that will export as Differential Input and elementary amplifying circuit, one-level is amplified electronic circuit and is produced reference potential and export simultaneously;
Reference potential feedback sub-circuit, be connected to the reference potential output that one-level amplifies electronic circuit, and adopt operational amplifier carry out active power filtering and amplify process, produce reference potential and export, and by reference potential output feedack to benchmark input end, feedover to capacitance-resistance filter electronic circuit simultaneously;
Further again, described filter circuit comprises two electronic circuits:
Bandpass filtering electronic circuit, is connected to the output of Differential Input and elementary amplifying circuit, carries out bandpass filtering to input signal;
Notch filter electronic circuit, is connected to the output of bandpass filtering electronic circuit, carries out 50Hz notch filter to the signal of input;
As shown in Figure 4, described secondary amplifies and voltage lifting circuit comprises operational amplifier U6A and U6B, reference power supply U10, resistance R20, R21, RW5, R27, R28, electric capacity C13, CC6, CS6, CC7, described secondary amplification is connected by resistance R20 mono-tunnel concatenation operation amplifier U6A negative input end with voltage lifting circuit input end, another road R21 and RW5 that connects according to the order of sequence is connected to the output of operational amplifier U6A, the positive input terminal ground connection of operational amplifier U6A, the output of operational amplifier U6A is connected with operational amplifier U6B positive input by resistance R27, reference power supply U10 output is leaded up to resistance U28 and is connected to operational amplifier U6B positive input terminal, separately lead up to electric capacity C13 ground connection, the negative input end of operational amplifier U6B is connected with the output of operational amplifier U6B, positive supply pin one tunnel of operational amplifier U6 meets 9V positive supply VCC, separately lead up to electric capacity CC6 ground connection, negative supply pin one tunnel of operational amplifier U6 meets-9V negative supply VSS, separately lead up to electric capacity CS6 ground connection, power pins one tunnel of reference power supply U10 meets 9V positive supply VCC, separately lead up to electric capacity CC7 ground connection, the enable pin of reference power supply U10 meets positive supply VCC, the output of operational amplifier U6B and described secondary amplify the output with voltage lifting circuit, also be the output of described physiological signal collection amplifying circuit.
As shown in Figure 5, described difference high resistant input electronic circuit comprises BiFET operational amplifier U1 and U2, resistance R6, R7, R8, electric capacity CC1, CC2, CS1, CS2, difference high resistant input electronic circuit positive input terminal is connected with BiFET operational amplifier U1 positive input, BiFET operational amplifier U1 negative input road is connected with BiFET operational amplifier U1 output by resistance R6, another road is connected with one end of resistance R7, difference high resistant input electronic circuit negative input end is connected with BiFET operational amplifier U2 positive input, BiFET operational amplifier U2 negative input road is connected with BiFET operational amplifier U2 output by resistance R8, another road is connected with the other end of resistance R7, the output pin of BiFET operational amplifier U1 is connected with the input CR+ of rc filter circuit, the output pin of BiFET operational amplifier U2 is connected with the input CR-of rc filter circuit, positive supply pin one tunnel of BiFET operational amplifier U1 meets 9V positive supply VCC, separately lead up to electric capacity CC1 ground connection, negative supply pin one tunnel of BiFET operational amplifier U1 meets-9V negative supply VSS, separately lead up to electric capacity CS1 ground connection, positive supply pin one tunnel of BiFET operational amplifier U2 meets 9V positive supply VCC, separately lead up to electric capacity CC2 ground connection, negative supply pin one tunnel of BiFET operational amplifier U2 meets-9V negative supply VSS, separately lead up to electric capacity CS2 ground connection.
As shown in Figure 6, described capacitance-resistance filter electronic circuit comprises electric capacity C3, C4, resistance R9, R10, capacitance-resistance filter electronic circuit input CR+ is connected with resistance R9 one end through electric capacity C2 mono-tunnel, another road is connected with the input OP1+ of one-level amplifying circuit, rc filter circuit input CR-is connected with resistance R10 one end through electric capacity C3 mono-tunnel, another road is connected with the input OP1-of one-level amplifying circuit, the resistance R9 other end is connected with the R10 other end, this tie point is connected with described Differential Input and the elementary output of amplifying circuit reference potential feedback sub-circuit and the output of operational amplifier U3 again, and be connected to the reference edge of physiological signal collection amplifying circuit.
As shown in Figure 7, described one-level is amplified electronic circuit and is comprised instrument amplifier U4, resistance R1, R2, R3, electric capacity CC3, CS3, wherein resistance R3 two gain control making pin accessing instrument amplifier U4 in parallel with resistance R1 after connecting with resistance R2, the output of instrument amplifier U4 is connected with the input of bandwidth-limited circuit, the intermediate point of resistance R2 with R3 is connected with the input of described Differential Input and elementary amplifying circuit reference potential feedback sub-circuit, positive supply pin one tunnel of instrument amplifier U4 meets 9V positive supply VCC, separately lead up to electric capacity CC3 ground connection, negative supply pin one tunnel of instrument amplifier U4 meets-9V negative supply VSS, separately lead up to electric capacity CS3 ground connection.
As shown in Figure 8, described reference potential feedback sub-circuit comprises operational amplifier U3, resistance R4, R5, electric capacity C1, CC4, CS4, wherein input one tunnel of reference potential feedback sub-circuit is connected with operational amplifier U3 negative input end, second tunnel is connected with resistance R5, the other end of resistance R5 is connected to the output of operational amplifier, 3rd tunnel is connected to the output of operational amplifier U3 through resistance R4 and electric capacity R1, the positive input terminal ground connection of operational amplifier, the output of operational amplifier U3 is connected to the intermediate point of R9 and R10 in described Differential Input and elementary amplifying circuit capacitance-resistance filter electronic circuit, positive supply pin one tunnel of operational amplifier U3 meets 9V positive supply VCC, separately lead up to electric capacity CC4 ground connection, negative supply pin one tunnel of operational amplifier U3 meets-9V negative supply VSS, separately lead up to electric capacity CS4 ground connection.
As shown in Figure 9, described pass filter electronic circuit comprises operational amplifier U5A and U5B, resistance R11, R12, R13, R14, R15, electric capacity C4, C5, C6, C7, C8, CC5, CS5, wherein the input of filter circuit bandpass filtering electronic circuit leads up to resistance R11 ground connection by electric capacity C4, second tunnel is connected with the negative input end of operational amplifier U5A by C5, 3rd tunnel is connected with the output of operational amplifier U5A by electric capacity C6, resistance R12 mono-termination operational amplifier U5A negative input end, the other end is connected with the output of operational amplifier U5A, the output of described operational amplifier U5A leads up to C7 ground connection by R13, second tunnel is connected with the negative input end of operational amplifier U5B by resistance R14, 3rd tunnel is connected with the output of operational amplifier U5B by resistance R15, electric capacity R8 mono-termination operational amplifier U5B negative input end, the other end is connected with the output of operational amplifier U5B, the output of U5B and the output of described filter circuit bandpass filtering electronic circuit, positive supply pin one tunnel of operational amplifier U5 meets 9V positive supply VCC, separately lead up to electric capacity CC5 ground connection, negative supply pin one tunnel of operational amplifier U5 meets-9V negative supply VSS, separately lead up to electric capacity CS5 ground connection.
As shown in Figure 10, described notch filter electronic circuit comprises operational amplifier U5C and U5D, resistance R23, R24, R25, RW2, RW3, RW4, RW1, R19, electric capacity C9, C10, C11, C12, described filter circuit notch filter electronic circuit input one tunnel series resistance R23 according to the order of sequence, RW2, RW3, then R24 is connected to operational amplifier U5D positive input terminal, another road series capacitance C9 according to the order of sequence, then C10 is connected to operational amplifier U5D positive input terminal, and electric capacity C9 is connected RW4 according to the order of sequence with C10 intermediate point, R25, then C11 is connected to the intermediate point of resistance RW2 and RW3, C12 and C11 is in parallel, the negative input end of operational amplifier U5D is connected with the output of operational amplifier U5D, operational amplifier output terminal contact resistance RW1 mono-tunnel concatenation operation amplifier U5C positive input terminal, separately lead up to resistance R19 ground connection, the negative input end of operational amplifier U5C is connected with the output of operational amplifier U5C, the tie point that the output of operational amplifier U5C is connected to resistance R25 and electric capacity R11 is formed and feeds back, and the output of output namely with described filter circuit notch filter electronic circuit of operational amplifier U5D amplifies with secondary and be connected with voltage lifting circuit input end.
In the present embodiment, described positive input, benchmark, negative input can be linked in sequence being aligned be connected to needed by human body measure muscle on gather electromyographic signal, also positive input terminal can be placed on dirty nearer position centrifugal relative to negative input end, reference edge is approximately placed in positive and negative input centre position, gathers electrocardiosignal.

Claims (9)

1. a physiological signal collection amplifying circuit, is characterized in that: comprising:
Differential Input and elementary amplifying circuit, be connected to the physiological signal of input, samples and amplify for the first time physiological signal;
Filter circuit, is connected to the output of Differential Input and elementary amplifying circuit, carries out bandpass filtering and 50Hz notch filter to the output signal of Differential Input and elementary amplifying circuit;
Secondary amplifies and voltage lifting circuit, is connected to the output of filter circuit, again amplifies and the minimum value signal after amplifying is raised to more than zero volt to the signal after filtering;
Wherein, described Differential Input and elementary amplifying circuit comprise:
Difference high resistant input electronic circuit, comprises positive input, benchmark, negative input three inputs, is connected to the diverse location of human body surface, and adopt two-way BiFET operational amplifier to carry out the process of difference high resistant to the physiological signal of positive input, negative input respectively;
Capacitance-resistance filter electronic circuit, is connected to the output of difference high resistant input electronic circuit, carries out the identical capacitance-resistance filter of filtering characteristic respectively to the output of two-way BiFET operational amplifier;
One-level amplifies electronic circuit, be connected to the output of capacitance-resistance filter electronic circuit, adopt instrument amplifier to export the two-way of capacitance-resistance filter electronic circuit and carry out differential amplification and the filter circuit of output supply rear class that will export as Differential Input and elementary amplifying circuit, one-level is amplified electronic circuit and is produced reference potential and export simultaneously;
Reference potential feedback sub-circuit, be connected to the reference potential output that one-level amplifies electronic circuit, and adopt operational amplifier carry out active power filtering and amplify process, produce reference potential and export, and by reference potential output feedack to benchmark input end, feedover to capacitance-resistance filter electronic circuit simultaneously.
2. physiological signal collection amplifying circuit as claimed in claim 1, is characterized in that: described filter circuit comprises:
Bandpass filtering electronic circuit, is connected to the output of Differential Input and elementary amplifying circuit, carries out bandpass filtering to input signal;
Notch filter electronic circuit, is connected to the output of bandpass filtering electronic circuit, carries out 50Hz notch filter to input signal.
3. physiological signal collection amplifying circuit as claimed in claim 1 or 2, it is characterized in that: described difference high resistant input electronic circuit comprises BiFET operational amplifier U1 and U2, resistance R6, R7, R8, electric capacity CC1, CC2, CS1, CS2, the positive input terminal of difference high resistant input electronic circuit is connected with BiFET operational amplifier U1 positive input, BiFET operational amplifier U1 negative input end road is connected with BiFET operational amplifier U1 output by resistance R6, another road is connected with one end of resistance R7, difference high resistant input electronic circuit negative input end is connected with BiFET operational amplifier U2 positive input, BiFET operational amplifier U2 negative input road is connected with BiFET operational amplifier U2 output by resistance R8, another road is connected with the other end of resistance R7, the output pin of BiFET operational amplifier U1 is connected with the input CR+ of capacitance-resistance filter electronic circuit, the output pin of BiFET operational amplifier U2 is connected with the input CR-of capacitance-resistance filter electronic circuit.
4. physiological signal collection amplifying circuit as claimed in claim 1 or 2, it is characterized in that: described capacitance-resistance filter electronic circuit comprises electric capacity C2, C3, resistance R9, R10, capacitance-resistance filter electronic circuit input CR+ is connected with resistance R9 one end through electric capacity C2 mono-tunnel, the input OP1+ that another road and one-level amplify electronic circuit is connected, capacitance-resistance filter electronic circuit input CR-is connected with resistance R10 one end through electric capacity C3 mono-tunnel, the input OP1-that another road and one-level amplify electronic circuit is connected, the resistance R9 other end is connected with the R10 other end, this tie point is connected with the output of reference potential feedback sub-circuit again.
5. physiological signal collection amplifying circuit as claimed in claim 1 or 2, it is characterized in that: described one-level is amplified electronic circuit and comprised instrument amplifier U4, resistance R1, R2, R3, electric capacity CC3, CS3, wherein resistance R3 two gain control making pin accessing instrument amplifier U4 in parallel with resistance R1 after connecting with resistance R2, the output OP1_OUT of instrument amplifier amplifies the output of electronic circuit as one-level and is connected with the input of filter circuit, and the intermediate point of resistance R2 with R3 is connected with the input of reference potential feedback sub-circuit.
6. physiological signal collection amplifying circuit as claimed in claim 1 or 2, it is characterized in that: reference potential feedback sub-circuit comprises operational amplifier U3, resistance R4, R5, electric capacity C1, CC4, CS4, wherein input one tunnel of reference potential feedback sub-circuit is connected with operational amplifier U3 negative input end, second tunnel is connected with resistance R5 one end, the other end of resistance R5 is connected to the output of operational amplifier U3, 3rd tunnel is connected to the output of operational amplifier U3 through resistance R4 and electric capacity C1, the positive input terminal ground connection of operational amplifier, output one tunnel of operational amplifier U3 is connected to the reference edge of Differential Input and elementary amplifying circuit, another road is connected to the intermediate point of R9 and R10 in capacitance-resistance filter electronic circuit.
7. physiological signal collection amplifying circuit as claimed in claim 2, it is characterized in that: described bandpass filtering electronic circuit comprises operational amplifier U5A and U5B, resistance R11, R12, R13, R14, R15, electric capacity C4, C5, C6, C7, C8, CC5, CS5, wherein the output of Differential Input and elementary amplifying circuit leads up to resistance R11 ground connection by electric capacity C4, second tunnel is connected with the negative input end of operational amplifier U5A by C5, 3rd tunnel is connected with the output of operational amplifier U5A by electric capacity C6, resistance R12 mono-termination operational amplifier U5A negative input end, the other end is connected with the output of operational amplifier U5A, the output of described operational amplifier U5A leads up to C7 ground connection by R13, second tunnel is connected with the negative input end of operational amplifier U5B by resistance R14, 3rd tunnel is connected with the output of operational amplifier U5B by resistance R15, electric capacity C8 mono-termination operational amplifier U5B negative input end, the other end is connected with the output of operational amplifier U5B, the output of U5B and the output BP_OUT of bandpass filtering electronic circuit.
8. physiological signal collection amplifying circuit as claimed in claim 2, is characterized in that: described notch filter electronic circuit comprises two operational amplifier U5C and U5D, resistance R23, R24, R25, RW2, RW3, RW4, RW1, R19, electric capacity C9, C10, C11, C12, described notch filter electronic circuit input one tunnel series resistance R23 according to the order of sequence, RW2, RW3, then R24 is connected to operational amplifier U5D positive input terminal, another road series capacitance C9 according to the order of sequence, then C10 is connected to operational amplifier U5D positive input terminal, and electric capacity C9 is connected RW4 according to the order of sequence with C10 intermediate point, R25, then C11 is connected to the intermediate point of resistance RW2 and RW3, C12 and C11 is in parallel, the negative input end of operational amplifier U5D is connected with the output of operational amplifier U5D, operational amplifier U5D output contact resistance RW1 mono-tunnel concatenation operation amplifier U5C positive input terminal, separately lead up to resistance R19 ground connection, the negative input end of operational amplifier U5C is connected with the output of operational amplifier U5C, the tie point that the output of operational amplifier U5C is connected to resistance R25 and electric capacity C11 is formed and feeds back, and the output of operational amplifier U5D and the output Trap_OUT of notch filter electronic circuit amplify with secondary and be connected with voltage lifting circuit input end.
9. physiological signal collection amplifying circuit as claimed in claim 1 or 2, it is characterized in that: described secondary amplifies and voltage lifting circuit comprises two operational amplifier U6A and U6B, reference power supply U10, resistance R20, R21, RW5, R27, R28, electric capacity C13, CC6, CS6, CC7, described secondary amplification is connected with operational amplifier U6A negative input end by resistance R20 mono-tunnel with voltage lifting circuit input end, another road R21 and RW5 that connects according to the order of sequence is connected to the output of operational amplifier U6A, the positive input terminal ground connection of operational amplifier U6A, the output of operational amplifier U6A is connected with operational amplifier U6B positive input by resistance R27, reference power supply U10 output is leaded up to resistance R28 and is connected to operational amplifier U6B positive input terminal, separately lead up to electric capacity C13 ground connection, the negative input end of operational amplifier U6B is connected with the output of operational amplifier U6B, the output of operational amplifier U6B and described secondary amplify the output with voltage lifting circuit, also be the output PS_OUT of described physiological signal collection amplifying circuit.
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