CN104906647B - Displacement liquid flow matches device and flow matches method in continuous blood purification - Google Patents

Displacement liquid flow matches device and flow matches method in continuous blood purification Download PDF

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Publication number
CN104906647B
CN104906647B CN201510405293.6A CN201510405293A CN104906647B CN 104906647 B CN104906647 B CN 104906647B CN 201510405293 A CN201510405293 A CN 201510405293A CN 104906647 B CN104906647 B CN 104906647B
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China
Prior art keywords
liquid
displacement liquid
dripping
flow matches
gear
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Expired - Fee Related
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CN201510405293.6A
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Chinese (zh)
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CN104906647A (en
Inventor
韩旭东
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3rd People's Hospital Of Nantong City
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3rd People's Hospital Of Nantong City
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654Dialysates therefor
    • A61M1/1656Apparatus for preparing dialysates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/0021Special media to be introduced, removed or treated removed from and reintroduced into the body, e.g. after treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/04Liquids
    • A61M2202/0413Blood

Abstract

The invention discloses displacement liquid flow matches device in a kind of continuous blood purification and flow matches method, the displacement liquid flow matches device includes liquid mixer and at least 2 groups dripping and leaking devices, each dripping and leaking device includes woven hose, dropper, turbine, axle and gear, wherein, the upper end of woven hose is provided with contact pin, and lower end connects with the upper end of dropper;Turbine and gear are respectively arranged on the upper and lower end of axle, turbine outer cylinder and dropper inwall inscribe;The gear external toothing of two adjacent dripping and leaking devices.The displacement liquid flow matches device that the present invention is provided can realize that real-time replacing base liquid is extracted and mixed in proportion, purpose just is prepared so as to reach, the batch production that can be standardized is prepared, reduce cost, and be avoided that the pollution of clinical configuration process, metering it is inaccurate, even wrong the problems such as, it is ensured that the inherent quality of displacement liquid, and be easy to long-term storage and transport, be conducive to quickly carrying out blood purification treatment, shorten the rescue time of critical patient.

Description

Displacement liquid flow matches device and flow matches method in continuous blood purification
Technical field
The present invention relates to a kind of Medical Devices, and in particular to displacement liquid flow matches device in a kind of continuous blood purification And flow matches method.
Background technology
Continuous blood purification refers to continuity and removes water and solute, is a kind of mode of environment in regulation, is contemporary severe The impressive progress of medical science, has evolved into the Important Platform and means of organ support.Removing moisture and solute unnecessary in vivo While, it is necessary to reasonable supplement beneficial solute and water.In blood purification, the water removed for supplement and the solute lost can According to plasma fraction, the liquid of the water and solute that are used to replace removing of configuration is referred to as displacement liquid, is needed when configuring displacement liquid Note the pH value and various electrolyte concentrations of displacement liquid.
In blood purification, closest displacement liquid is clinical optimal selection with plasma fraction.Carbonate displacement liquid is The displacement liquid configured by base of carbonic acid, it is most like with human plasma composition, but due to carbonic acid base can with the calcium in displacement liquid, Magnesium ion forms water insoluble precipitation, not only changes displacement liquid composition, and small precipitation can be deposited to microcirculation, making patients The state of an illness.In addition, carbonate decomposable asymmetric choice net generate carbon dioxide, cause displacement liquid unstable, it is impossible to industrialized production, clinically for gram Take drawbacks described above, more using now with the current or be respectively connected to using Y type interfaces, it is now with the current at least need more than half an hour when Between, clinical preparation is dramatically increased to the time really implemented, and is unfavorable for operation for the critical patient that time is life Implement as early as possible.
The displacement liquid of energy industrialized production is generally lactate displacement liquid or Chinese holly edge hydrochlorate displacement liquid, although both displacement liquids Performance is stable, can preserve for a long time, but both are both needed to the metabolism in liver and are converted to carbonate, have aggravated burden of liver.
The content of the invention
The present invention seeks to solve the above problems there is provided a kind of determination for overcoming carbonate displacement liquid unstable, simultaneously Displacement liquid industrialized production is may be such that, the operating efficiency of blood purification is improved, simplifies blood purification implementing procedure, reduces and matches somebody with somebody liquid mistake Displacement liquid flow matches device and flow matches method in the continuous blood purification of pollution that may be present in journey.
To reach above-mentioned purpose, the technical solution adopted by the present invention is:Flow quantity is replaced in a kind of continuous blood purification Coalignment, including liquid mixer and at least 2 groups dripping and leaking devices, each dripping and leaking device include woven hose, dropper, whirlpool Wheel, axle and gear, wherein,
The upper end of the woven hose is provided with contact pin, and lower end connects with the upper end of dropper;
The turbine and gear are respectively arranged on the upper and lower end of axle, and the turbine is in dropper, in its outer cylinder and dropper Wall inscribe;
The gear external toothing of two adjacent dripping and leaking devices;
The lower end of each dripping and leaking device is communicated with liquid mixer.
Wherein, in the upper end insertion displacement liquid of the contact pin, the proportioning and two water clocks of the displacement liquid of two dripping and leaking devices are flowed through The gear ratio of device is equal.
Further, the contact pin is provided with several side openings.
Wherein, the woven hose is provided with thumbwheel switch.
Wherein, the lower woven hose for conveying displacement liquid to patient, the lower transfusion are connected with the liquid mixer Shrink-ring is provided with the inside of the oral area of pipe, outboard cover is provided with head protector.
The present invention also provides a kind of flow using displacement liquid flow matches device in above-mentioned continuous blood purification Method of completing the square, includes preparation, the assembling of displacement liquid flow matches device, the preparation of displacement liquid of displacement liquid flow matches device, its In,
1st, the preparation of displacement liquid flow matches device comprises the following steps:
(1-1)By 100 parts by weight high polymer materials, 0.1~3 parts by weight of inorganic antiseptic, 0.5~3 parts by weight slow releasing medicinal Thing, 30~50 parts by weight of plasticizer, 3~10 parts by weight lubricating modification agent, 2~6 parts by weight stabilizers and the punching of 10~30 parts by weight Hit modifying agent to mix in proportion, composite is made;
(1-2)Composite is placed in plastic extruder, is extruded at a temperature of 150~180 DEG C and uses pelleter pelletizing, Obtain medical antibacterial plastic grain;
(1-3)By step(1-2)Gained medical antibacterial plastic grain is placed in extruder, is extruded by extruding cooling method Several carry the dropper of woven hose;
(1-4)By step(1-2)Gained medical antibacterial plastic grain is placed in injection machine, at a temperature of 180~260 DEG C Several turbines of injection molding and axle;
(1-5)By step(1-2)Gained medical antibacterial plastic grain is placed in injection machine, at a temperature of 210~260 DEG C The gear of injection molding several sizes, the number of teeth not etc.;
(1-6)By step(1-2)Gained medical antibacterial plastic grain is placed in extruder, is extruded by extruding cooling method Liquid mixer, and the mounting hole being connected with dropper is opened up in the upper end of liquid mixer, lower end offers displacement liquid outlet;
2nd, the assembling of displacement liquid flow matches device comprises the following steps:
(2-1)Turbine and gear are installed on to the upper and lower side of axle respectively;
(2-2)Turbine is inserted in dropper, it is ensured that turbine outer cylinder and dropper inwall inscribe;
(2-3)Contact pin is installed in woven hose upper end, thumbwheel switch is installed at least one woven hose;
(2-4)Repeat step(2-1)~(2-3), prepare multigroup dripping and leaking device;
(2-5)According to the species of stoste needed for configuration displacement liquid, the dripping and leaking device of respective amount is passed through into mounting hole and liquid Body blender is fixedly connected, and ensures the gear external toothing of connected dripping and leaking device after connection;
(2-6)The woven hose under the displacement liquid exit connection of liquid mixer lower end, for conveying displacement liquid to patient;
3rd, the preparation of displacement liquid comprises the following steps:
(3-1)At least prepare two kinds of each portions of replacing base liquid;
(3-2)The contact pin correspondence of dripping and leaking device is inserted in replacing base liquid, the wherein few gear mesh of the number of teeth answers aequum Larger replacing base liquid;
(3-3)The drop speed of displacement liquid according to required by sufferer situation opens the thumbwheel switch of two dripping and leaking devices, wherein one When kind replacing base liquid flows through turbine, cause turbine rotation, drive and the gear of turbine linkage is rotated at the same speed, this kind of replacing base Liquid mixer is advanced under liquid;Another gear engaged with the gear is transmitted according to gearratio, and it is another that drive links therewith One turbine rotation so that another replacing base liquid is descending, multigroup dripping and leaking device is similarly run, and the flow of a variety of replacing base liquids is obtained Obtain and accurately match, and mixed in liquid mixer, form displacement liquid.
Wherein, the replacing base liquid is respectively blood purification replacing base liquid, the alkalies configured with reference to plasma fraction Body.
It is preferred that, the blood purification replacing base liquid includes sodium, potassium, calcium, magnesium, chlorine, sugar, and the akaline liquid is 5% Soviet Union Fetch water.
Because above-mentioned technical proposal is used, the present invention has following advantages compared with prior art:
1st, the displacement liquid flow matches device that the present invention is provided can realize real-time blood purification replacing base liquid and clinic The most commonly used akaline liquid(5% soda water)Extracted and mixed in proportion, purpose just is prepared so as to reach, can be with The batch production that is standardized is prepared, and reduces cost, and be avoided that the pollution of clinical configuration process, metering it is inaccurate, very The problems such as to mistake, it is ensured that the inherent quality of displacement liquid, and it is easy to long-term storage and transport, be conducive to quickly carrying out blood Purification treatment, shortens the rescue time of critical patient.
2nd, the displacement liquid prepared using the displacement liquid flow matches device and flow matches method of the present invention is not required in liver Middle metabolic conversion is carbonate, and the problem of aggravate burden of liver;Also be not in carbonic acid base and the calcium in displacement liquid, magnesium shape Into precipitation, situations such as carbonate decomposition forms carbon dioxide, displacement liquid is stable, can industrialized production.
Brief description of the drawings
Fig. 1 is the structure diagram of the embodiment of the present invention one.
Description of reference numerals:
1st, liquid mixer;
2nd, woven hose;
3rd, dropper;
4th, turbine;
5th, axle;
6th, gear;
7th, contact pin;70th, side opening.
Embodiment
Below in conjunction with the accompanying drawings and embodiment the invention will be further described:
Embodiment one:Shown in Fig. 1, displacement liquid flow matches device in a kind of continuous blood purification, including liquid mixing Device 1 and at least 2 groups dripping and leaking devices, each dripping and leaking device include woven hose 2, dropper 3, turbine 4, axle 5 and gear 6, wherein,
The upper end of the woven hose 2 is provided with contact pin 7, and lower end connects with the upper end of dropper 3;
The turbine 4 and gear 6 are respectively arranged on the upper and lower end of axle 5, the turbine 4 in dropper 3, its outer cylinder with Dropper inwall inscribe;
The external toothing of gear 6 of two adjacent dripping and leaking devices;
The lower end of each dripping and leaking device is communicated with liquid mixer 1.
In the upper end insertion displacement liquid of the contact pin 7, the proportioning and two dripping and leaking devices of the displacement liquid of two dripping and leaking devices are flowed through Gear ratio it is equal.
The contact pin 7 is provided with several side openings 70.
The woven hose 2 is provided with thumbwheel switch.
The lower woven hose for conveying displacement liquid to patient is connected with the liquid mixer 1, the lower woven hose Shrink-ring is provided with the inside of oral area, outboard cover is provided with head protector.
The embodiment of the present invention one also provides displacement liquid flow matches device in a kind of above-mentioned continuous blood purification of utilization Flow matches method, including the preparation of displacement liquid flow matches device, the assembling of displacement liquid flow matches device, displacement liquid Prepare, wherein,
1st, the preparation of displacement liquid flow matches device comprises the following steps:
(1-1)By 100 parts by weight high polymer materials, 0.1~3 parts by weight of inorganic antiseptic, 0.5~3 parts by weight slow releasing medicinal Thing, 30~50 parts by weight of plasticizer, 3~10 parts by weight lubricating modification agent, 2~6 parts by weight stabilizers and the punching of 10~30 parts by weight Hit modifying agent to mix in proportion, composite is made;
(1-2)Composite is placed in plastic extruder, is extruded at a temperature of 150~180 DEG C and uses pelleter pelletizing, Obtain medical antibacterial plastic grain;
(1-3)By step(1-2)Gained medical antibacterial plastic grain is placed in extruder, is extruded by extruding cooling method Several carry the dropper of woven hose;
(1-4)By step(1-2)Gained medical antibacterial plastic grain is placed in injection machine, at a temperature of 180~260 DEG C Several turbines of injection molding and axle;
(1-5)By step(1-2)Gained medical antibacterial plastic grain is placed in injection machine, at a temperature of 210~260 DEG C The gear of injection molding several sizes, the number of teeth not etc.;
(1-6)By step(1-2)Gained medical antibacterial plastic grain is placed in extruder, is extruded by extruding cooling method Liquid mixer, and the mounting hole being connected with dropper is opened up in the upper end of liquid mixer, lower end offers displacement liquid outlet, liquid The wherein side wall of body blender can be opened, for gear to be put into.
2nd, the assembling of displacement liquid flow matches device comprises the following steps:
(2-1)Turbine and gear are installed on to the upper and lower side of axle respectively;
Note:The gear of the different numbers of teeth according to the difference of replacing base liquid hold-up in displacement liquid, can be changed, blood is not limited to Purification, the liquid proportion available for any occasion;
(2-2)Turbine is inserted in dropper, it is ensured that turbine outer cylinder and dropper inwall inscribe and position in the axial direction;
(2-3)Contact pin is installed in woven hose upper end, thumbwheel switch is installed at least one woven hose;
(2-4)Repeat step(2-1)~(2-3), prepare multigroup dripping and leaking device;
(2-5)According to the species of stoste needed for configuration displacement liquid, the dripping and leaking device of respective amount is passed through into mounting hole and liquid Body blender is fixedly connected, and ensures the gear external toothing of connected dripping and leaking device after connection;
(2-6)The woven hose under the displacement liquid exit connection of liquid mixer lower end, for conveying displacement liquid to patient.
3rd, the preparation of displacement liquid comprises the following steps:
(3-1)At least prepare two kinds of each portions of replacing base liquid;
(3-2)The contact pin correspondence of dripping and leaking device is inserted in replacing base liquid, the wherein few gear mesh of the number of teeth answers aequum Larger replacing base liquid;
(3-3)The drop speed of displacement liquid according to required by sufferer situation opens the thumbwheel switch of two dripping and leaking devices, wherein one When kind replacing base liquid flows through turbine, cause turbine rotation, drive and the gear of turbine linkage is rotated at the same speed, this kind of replacing base Liquid mixer is advanced under liquid;Another gear engaged with the gear is transmitted according to gearratio, and it is another that drive links therewith One turbine rotation so that another replacing base liquid is descending, multigroup dripping and leaking device is similarly run, and the flow of a variety of replacing base liquids is obtained Obtain and accurately match, and mixed in liquid mixer, form displacement liquid.
In the present embodiment, displacement liquid flow matches device is provided with 2 groups of dripping and leaking devices, for the mixing of replacing base liquid in 2, 2 kinds of replacing base liquids are respectively blood purification replacing base liquid, 5% soda water configured with reference to plasma fraction(Na2CO3).
Wherein, the blood purification replacing base liquid includes sodium, potassium, calcium, magnesium, chlorine, sugar, and the akaline liquid is.
The displacement liquid flow matches device that the present invention is provided can realize real-time blood purification replacing base liquid and clinic most For conventional akaline liquid(5% soda water)Extracted and mixed in proportion, purpose just, Ke Yijin are prepared so as to reach The batch production of professional etiquette generalized is prepared, and reduces cost, and be avoided that the pollution of clinical configuration process, metering it is inaccurate, even The problems such as mistake, it is ensured that the inherent quality of displacement liquid, and be easy to long-term storage and transport, be conducive to quickly carrying out blood net Change treatment, shorten the rescue time of critical patient.
The displacement liquid prepared using the displacement liquid flow matches device and flow matches method of the present invention is not required in liver Metabolic conversion is carbonate, and the problem of aggravate burden of liver;Also be not in that carbonic acid base is formed with the calcium in displacement liquid, magnesium Situations such as precipitation, carbonate decomposition formation carbon dioxide, displacement liquid is stable, can industrialized production.
Described above is the preferred embodiment of the present invention, it is noted that for those skilled in the art For, on the premise of principle of the present invention is not departed from, some improvement or replacement can also be made, these improve or replaced It should be regarded as protection scope of the present invention.

Claims (6)

1. displacement liquid flow matches device in a kind of continuous blood purification, it is characterised in that including liquid mixer and at least 2 Group dripping and leaking device, each dripping and leaking device includes woven hose, dropper, turbine, axle and gear, wherein,
The upper end of the woven hose is provided with contact pin, and lower end connects with the upper end of dropper;
The turbine and gear are respectively arranged on the upper and lower end of axle, and the turbine is in dropper, in its outer cylinder and dropper inwall Cut;
The gear external toothing of two adjacent dripping and leaking devices;
The lower end of each dripping and leaking device is communicated with liquid mixer;
The woven hose is provided with thumbwheel switch;
In the upper end insertion displacement liquid of the contact pin, the proportioning and the gear of two dripping and leaking devices of the displacement liquid of two dripping and leaking devices are flowed through Gearratio is equal.
2. displacement liquid flow matches device in continuous blood purification according to claim 1, it is characterised in that described to insert Pin is provided with several side openings.
3. displacement liquid flow matches device in continuous blood purification according to claim 1, it is characterised in that the liquid It is connected with body blender on the inside of the lower woven hose for conveying displacement liquid to patient, the oral area of the lower woven hose provided with deflation Ring, outboard cover is provided with head protector.
4. one kind is using such as displacement liquid flow matches device in continuous blood purification according to any one of claims 1 to 3 Flow matches method, it is characterised in that the preparation including displacement liquid flow matches device, the group of displacement liquid flow matches device Dress, the preparation of displacement liquid, wherein,
1st, the preparation of displacement liquid flow matches device comprises the following steps:
(1-1)By 100 parts by weight high polymer materials, 0.1~3 parts by weight of inorganic antiseptic, 0.5~3 parts by weight slow releasing pharmaceutical, 30~50 parts by weight of plasticizer, 3~10 parts by weight lubricating modification agent, 2~6 parts by weight stabilizers and the impact of 10~30 parts by weight change Property agent is mixed in proportion, and composite is made;
(1-2)Composite is placed in plastic extruder, is extruded at a temperature of 150~180 DEG C and uses pelleter pelletizing, obtained Medical antibacterial plastic grain;
(1-3)By step(1-2)Gained medical antibacterial plastic grain is placed in extruder, some by extruding cooling method extrusion The individual dropper with woven hose;
(1-4)By step(1-2)Gained medical antibacterial plastic grain is placed in injection machine, at a temperature of 180~260 DEG C Several turbines of injection molding and axle;
(1-5)By step(1-2)Gained medical antibacterial plastic grain is placed in injection machine, at a temperature of 210~260 DEG C The gear of injection molding several sizes, the number of teeth not etc.;
(1-6)By step(1-2)Gained medical antibacterial plastic grain is placed in extruder, and liquid is extruded by extruding cooling method Blender, and the mounting hole being connected with dropper is opened up in the upper end of liquid mixer, lower end offers displacement liquid outlet;
2nd, the assembling of displacement liquid flow matches device comprises the following steps:
(2-1)Turbine and gear are installed on to the upper and lower side of axle respectively;
(2-2)Turbine is inserted in dropper, it is ensured that turbine outer cylinder and dropper inwall inscribe;
(2-3)Contact pin is installed in woven hose upper end, thumbwheel switch is installed at least one woven hose;
(2-4)Repeat step(2-1)~(2-3), prepare multigroup dripping and leaking device;
(2-5)According to the species of stoste needed for configuration displacement liquid, the dripping and leaking device of respective amount is mixed by mounting hole with liquid Clutch is fixedly connected, and ensures the gear external toothing of connected dripping and leaking device after connection;
(2-6)The woven hose under the displacement liquid exit connection of liquid mixer lower end, for conveying displacement liquid to patient;
3rd, the preparation of displacement liquid comprises the following steps:
(3-1)At least prepare two kinds of each portions of replacing base liquid;
(3-2)The contact pin correspondence of dripping and leaking device is inserted in replacing base liquid, the wherein few gear mesh of the number of teeth answers aequum larger Replacing base liquid;
(3-3)The drop speed of displacement liquid according to required by sufferer situation opens the thumbwheel switch of two dripping and leaking devices, and one of which is put When changing basal liquid and flowing through turbine, cause turbine rotation, drive the gear with turbine linkage to rotate at the same speed, under this kind of replacing base liquid It is advanced into liquid mixer;Another gear engaged with the gear is transmitted according to gearratio, drives another whirlpool linked therewith Wheel is rotated so that another replacing base liquid is descending, and multigroup dripping and leaking device is similarly run, and the flow of a variety of replacing base liquids obtains essence Really proportioning, and being mixed in liquid mixer, forms displacement liquid.
5. flow matches method according to claim 4, it is characterised in that the replacing base liquid is respectively with reference to blood plasma Blood purification replacing base liquid, the akaline liquid of composition configuration.
6. flow matches method according to claim 5, it is characterised in that the blood purification replacing base liquid is included Sodium, potassium, calcium, magnesium, chlorine, sugar, the akaline liquid are 5% soda water.
CN201510405293.6A 2015-07-13 2015-07-13 Displacement liquid flow matches device and flow matches method in continuous blood purification Expired - Fee Related CN104906647B (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995007066A1 (en) * 1993-09-07 1995-03-16 Debiotech S.A. Syringe device for mixing two compounds
CN1193919A (en) * 1995-08-25 1998-09-23 生物技术公司 Continuously operating infusion device and method
CN102284102A (en) * 2011-07-25 2011-12-21 广东工业大学 Disposable closed deflating blood transfusion device
CN103402619A (en) * 2010-12-24 2013-11-20 厄弗翁简易股份公司 Device for mixing at least two constituents
CN204840432U (en) * 2015-07-13 2015-12-09 南通市第三人民医院 Replacement liquid stream volume matching unit during continuity blood purifies

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995007066A1 (en) * 1993-09-07 1995-03-16 Debiotech S.A. Syringe device for mixing two compounds
CN1193919A (en) * 1995-08-25 1998-09-23 生物技术公司 Continuously operating infusion device and method
CN103402619A (en) * 2010-12-24 2013-11-20 厄弗翁简易股份公司 Device for mixing at least two constituents
CN102284102A (en) * 2011-07-25 2011-12-21 广东工业大学 Disposable closed deflating blood transfusion device
CN204840432U (en) * 2015-07-13 2015-12-09 南通市第三人民医院 Replacement liquid stream volume matching unit during continuity blood purifies

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