CN104906496A

CN104906496A - Traditional Chinese medicine composition for treating anthracemia delayed encephalopathy

Info

Publication number: CN104906496A
Application number: CN201510337932.XA
Authority: CN
Inventors: 赵振升
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-06-17
Filing date: 2015-06-17
Publication date: 2015-09-16

Abstract

The invention discloses a traditional Chinese medicine composition for treating an anthracemia delayed encephalopathy. The traditional Chinese medicine composition comprises the following components by weight: 10-20g of old radish root, 10-20g of wild ginger leaf, 5-10g of peppermint, 5-10g of danshen root, 5-10g of fragrant solomonseal rhizome, 8-12g of Szechuan lovage rhizome, 8-12g of tuber fleeceflower root, 8-12g of weeping forsythia capsule, 8-12g of villous amomum fruit, 8-15g of peach seed, 10-20g of indigowoad root, 8-12g of Chinese taxillus twig, 10-20g of rhubarb, 10-20g of coptis root and 5-10g of licorice root. The components are used together to achieve the effects of tonifying liver and kidney, promoting intelligence and restoring consciousness, activating blood circulation to remove blood stases and clearing away heat and toxic materials, so that the traditional Chinese medicine composition can enhance the body immune system, quickly improve symptoms of cerebral ischemia, hypoxia and the like, and accelerate the regeneration of brain cells and the recovery of brain functions, thereby achieving the aim of improving and curing the anthracemia delayed encephalopathy.

Description

A kind of Chinese medicine composition for the treatment of delayed encephalopathy after acute carbon monoxide poisoning

Technical field

The invention belongs to the field of Chinese medicines, specifically a kind of Chinese medicine composition for the treatment of delayed encephalopathy after acute carbon monoxide poisoning.

Background technology

Delayed encephalopathy after acute carbon monoxide poisoning refers to that a part of patients with acute carbon monoxide poisoning is after acute poisoning glucose recovery, the a series of spirit, the neurological disorder that occur after " latent phase " after a while, it is the most serious complication of ACMP, serious poisoner's 10% ~ 30% can occur, even occur without any during cerebral lesion after patients acuity exposes carbon monoxide, the time occurred is several days to several months (3 ~ 240 days) after acute exposure, and this stage is also called the bright phase.The survivor of 10% has obvious neuropsychic symptom (dementia, amnestic syndrome, parkinson disease, dancing are levied, aphasia, apraxia, cortical blindness, epilepsy, hallucination, psychological problem), more patients have spared nerve mental defect, comprise abnormality of personality and cognitive disorder.The incidence rate of mild cognitive impairment can, up to 67%, also have the poisoner of 18% something lost to have psychoneural disease even if experience hyperbaric oxygentherapy after 12 months.

Delayed encephalopathy after acute carbon monoxide poisoning does not have specific medicine at present, and prognosis is poor, and disability rate is high.Therefore take effective care method to improve the treatment enthusiasm of patient and family members, promote that patient returns to one's perfect health very important.The traditional Chinese medical science thinks that this disease belongs to " dementia ", " forgetful " category, think that qi depression to blood stasis, key network impatency are its pathology, therefore, in recent years we treat according to differential diagnosis in tcm, the principle for the treatment of both the principal and secondary aspects of a disease, utilize multiple Chinese herbal medicine to mix fried this disease of traditional Chinese medicine composition for treating and achieve good curative effect.

Summary of the invention

The invention solves the defect existed in treatment delayed encephalopathy after acute carbon monoxide poisoning at present, provide the Chinese medicine composition that a kind of determined curative effect, cure rate are high, not easily recur.

The technical solution adopted in the present invention is: a kind of Chinese medicine composition for the treatment of delayed encephalopathy after acute carbon monoxide poisoning, is characterized in that, described Chinese medicine composition is made up of the Chinese medicine of following weight portion:

Withered trailing plants 10-20 gram, ground, 10-20 gram, Fructus Hedychii Spicati leaf, Herba Menthae 5-10 gram, Radix Salviae Miltiorrhizae 5-10 gram, Rhizoma Polygonati Odorati 5-10 gram, Rhizoma Chuanxiong 8-12 gram, Radix Polygoni Multiflori 8-12 gram, Fructus Forsythiae 8-12 gram, Fructus Amomi 8-12 gram, Semen Persicae 8-15 gram, Radix Isatidis 10-20 gram, Herba Taxilli 8-12 gram, Radix Et Rhizoma Rhei 10-20 gram, Rhizoma Coptidis 10-20 gram, Radix Glycyrrhizae 5-10 gram.

As a kind of prioritization scheme:

Described Chinese medicine composition is made up of the Chinese medicine of following weight portion:

Ground withered trailing plants 10 grams, 10 grams, Fructus Hedychii Spicati leaf, Herba Menthae 5 grams, Radix Salviae Miltiorrhizae 5 grams, Rhizoma Polygonati Odorati 5 grams, Rhizoma Chuanxiong 8 grams, the Radix Polygoni Multiflori 8 grams, Fructus Forsythiae 8 grams, Fructus Amomi 8 grams, 8 grams, Semen Persicae, Radix Isatidis 10 grams, Herba Taxilli 8 grams, Radix Et Rhizoma Rhei 10 grams, Rhizoma Coptidis 10 grams, 5 grams, Radix Glycyrrhizae.

As a kind of prioritization scheme:

Ground withered trailing plants 12 grams, 12 grams, Fructus Hedychii Spicati leaf, Herba Menthae 6 grams, Radix Salviae Miltiorrhizae 6 grams, Rhizoma Polygonati Odorati 6 grams, Rhizoma Chuanxiong 9 grams, the Radix Polygoni Multiflori 9 grams, Fructus Forsythiae 9 grams, Fructus Amomi 9 grams, 10 grams, Semen Persicae, Radix Isatidis 12 grams, Herba Taxilli 9 grams, Radix Et Rhizoma Rhei 12 grams, Rhizoma Coptidis 12 grams, 6 grams, Radix Glycyrrhizae.

As a kind of prioritization scheme:

Ground withered trailing plants 14 grams, 14 grams, Fructus Hedychii Spicati leaf, Herba Menthae 7 grams, Radix Salviae Miltiorrhizae 7 grams, Rhizoma Polygonati Odorati 7 grams, Rhizoma Chuanxiong 10 grams, the Radix Polygoni Multiflori 10 grams, Fructus Forsythiae 10 grams, Fructus Amomi 10 grams, 10 grams, Semen Persicae, Radix Isatidis 14 grams, Herba Taxilli 10 grams, Radix Et Rhizoma Rhei 14 grams, Rhizoma Coptidis 14 grams, 7 grams, Radix Glycyrrhizae.

As a kind of prioritization scheme:

Ground withered trailing plants 16 grams, 16 grams, Fructus Hedychii Spicati leaf, Herba Menthae 8 grams, Radix Salviae Miltiorrhizae 8 grams, Rhizoma Polygonati Odorati 8 grams, Rhizoma Chuanxiong 10 grams, the Radix Polygoni Multiflori 10 grams, Fructus Forsythiae 9 grams, Fructus Amomi 9 grams, 12 grams, Semen Persicae, Radix Isatidis 16 grams, Herba Taxilli 10 grams, Radix Et Rhizoma Rhei 16 grams, Rhizoma Coptidis 16 grams, 8 grams, Radix Glycyrrhizae.

As a kind of prioritization scheme:

Ground withered trailing plants 18 grams, 18 grams, Fructus Hedychii Spicati leaf, Herba Menthae 9 grams, Radix Salviae Miltiorrhizae 9 grams, Rhizoma Polygonati Odorati 9 grams, Rhizoma Chuanxiong 11 grams, the Radix Polygoni Multiflori 11 grams, Fructus Forsythiae 11 grams, Fructus Amomi 11 grams, 13 grams, Semen Persicae, Radix Isatidis 18 grams, Herba Taxilli 11 grams, Radix Et Rhizoma Rhei 18 grams, Rhizoma Coptidis 18 grams, 9 grams, Radix Glycyrrhizae.

As a kind of prioritization scheme:

Ground withered trailing plants 20 grams, 20 grams, Fructus Hedychii Spicati leaf, Herba Menthae 10 grams, Radix Salviae Miltiorrhizae 10 grams, Rhizoma Polygonati Odorati 10 grams, Rhizoma Chuanxiong 12 grams, the Radix Polygoni Multiflori 12 grams, Fructus Forsythiae 12 grams, Fructus Amomi 12 grams, 15 grams, Semen Persicae, Radix Isatidis 20 grams, Herba Taxilli 12 grams, Radix Et Rhizoma Rhei 20 grams, Rhizoma Coptidis 20 grams, 10 grams, Radix Glycyrrhizae.

The instructions of taking of Chinese medicine composition of the present invention is: after being mixed by the raw material Chinese medicine of above-mentioned weight proportion, traditionally the method for fried Chinese medicine gets its medicine juice, every day 1 dose, point sooner or later 2 times oral.20 doses was 1 course for the treatment of.

The raw material Chinese medicine of above-mentioned Chinese medicine composition:

The withered trailing plants in ground, has another name called Semen Raphani, acrid in the mouth, sweet, and property is put down; Return spleen, stomach, lung meridian.There is the de-swelling that helps digestion, effect of lowering the adverse-rising QI to resolve phlegm.Modern pharmacological research, proves that Semen Raphani is containing antibiotic substance raphanin, all has certain inhibitory action to streptococcus pneumoniae, staphylococcus, escherichia coli, streptococcus etc.

Fructus Hedychii Spicati leaf, warm in nature, acrid in the mouth.Have warming middle-JIAO to regulate the flow of vital energy, wind-expelling pain-stopping, detumescence, effect of promoting blood circulation to remove blood stasis, modern pharmacological research, Fructus Hedychii Spicati leaf includes australene, β, pinene, β-phellandrene, for the aphonia caused by diseases caused by exogenous pathogenic factor ailment said due to cold or exposure; Cold or the cough caused by lung cold, asthma; Women's amenorrhea due to stagnation of blood, or menstruation is delayed; Traumatic injury, or waist abdomen cold type of pain; Scrofula, aphtha of the mouth and tongue etc.

Herba Menthae, acrid in the mouth, cool in nature; Return lung, Liver Channel.Merit has dispelling wind and heat pathogens, the clear sharp head, sore-throat relieving rash, effect of dispersing the stagnated live-QI to relieve the stagnation of QI.Modern pharmacological research, Herba Menthae antivirus action, aqua methnae decoct has inhibitory action to viral ECHO11 strain, and Mentholum has very strong bactericidal action.

Radix Salviae Miltiorrhizae, bitter in the mouth, cold nature; GUIXIN, pericardium, Liver Channel.There is promoting blood circulation to remove blood stasis, detumescence hemostasis, anti-inflammatory analgetic, menstruction regulating and pain relieving, coronary artery dilator, improve myocardial ischemia situation, reduce blood pressure, calm the nerves with all worries set aside, blood sugar lowering and the effect such as antibacterial, medical experiment proves, Radix Salviae Miltiorrhizae also has anti-platelet aggregation, reduces the function of blood viscosity and the inside and outside blood coagulation system of adjustment, is the natural Chinese medicine that a kind of safety treats again cardiovascular disease reliably.

Rhizoma Polygonati Odorati, sweet in the mouth, property is put down.Return lung; Stomach warp.Have effect of nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, modern pharmacological research, these product have promotion laboratory animal antibody tormation, improve phagocytic percentage and the phagocytic index of macrophage, promote interferon synthesis, suppress growth of bacillus tubercle, blood sugar lowering, blood fat reducing, alleviates atherosclerotic plaque and is formed, make peripheral blood vessel and coronary dilation, extend hypoxia endurance time, heart tonifying, antioxidation, the anti-ageing effect of waiting for a long time.

Rhizoma Chuanxiong, acrid in the mouth, warm in nature; Return liver, gallbladder, pericardium channel.There is blood-activating and qi-promoting, effect of wind-expelling pain-stopping.For pacifying nerve, positive wind syndrome of head headache, lump in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.

The Radix Polygoni Multiflori, sweet in the mouth, property is put down; GUIXIN, Liver Channel.There is nourishing blood to tranquillize the mind, effect of dispelling wind and removing obstruction in the collateral.Modern pharmacological research, the Radix Polygoni Multiflori has obvious hemopoietic and strengthens the function of immunocompetence, can significantly increase protein content in brain regulating liver-QI, promote the Regeneration and Repair of neurocyte.

Fructus Forsythiae, bitter in the mouth, cold nature; Return lung, heart channel.Include the material such as forsythol, sterol compound, Saponin (without hemolytic) and Flavonoids, horse tongue resinol glycoside, there is effect of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, benefiting QI for strengthening the superficies.

Fructus Amomi, acrid in the mouth, warm in nature; Return spleen, stomach, kidney channel.There is removing dampness appetizing, warming spleen and stopping diarrha, antiabortive effect of regulating the flow of vital energy.

Semen Persicae, sweet in the mouth, hardship, property is put down; Return lung, liver, large intestine channel.Have blood circulation promoting and blood stasis dispelling, moisturize effect of laxation, Semen Persicae main attack blood stasis and be liver medicine, holding concurrently and dredge the stasis of blood of the skin natural fibre line of meat, is the special medicine that blood stasis blood closes.Bitter to let out stagnant blood, sweet with tissue regeneration promoting blood.

Radix Isatidis bitter in the mouth, cold in nature; GUIXIN, stomach warp.Cure mainly maculae caused by violent heat pathogen; High heat headache; Major part pestilence; Crimson tongue is purple dark, scarlet fever; Erysipelas; Mumps; Sore throat; Skin ulcer is swollen, carbuncle; Chickenpox; Measles; Hepatitis; Influenza, epidemic encephalitis, encephalitis b, pneumonia, coma tells nosebleed, pharyngeal swelling, acute catarrhal conjunctivitis, skin ulcer rash; Can prevent and treat epidemic encephalitis type B, acute, chronic hepatitis, mumps, osteomyelitis, root decoct has bacteriostasis to Grain-positive and negative bacteria, and the acetone extract of root and the acetone extract of leaf also have bacteriostasis.

Herba Taxilli, bitter in the mouth, sweet, property is put down; Return liver, kidney channel.Have liver and kidney tonifying, strengthening the tendons and bones, QI invigorating is antiabortive, effect of remove rheumatism.Modern pharmacological research, Herba Visci total glycosides can suppress hematoblastic gathering, prevents its active substance from discharging, improves microcirculation, thus avoid vasoconstriction and thrombosis.

Radix Et Rhizoma Rhei bitter in the mouth, cold in nature; Return spleen, stomach, large intestine, liver, pericardium channel.There is anti-infectious function, the chrysophanic acid in Radix Et Rhizoma Rhei, emodin, aloe-emodin, affect the enzyme system of folic acid; Anti-bacteria nucleic acid and protein synthesis; Anti-bacteria biological oxidation enzyme system; Inducement interferon, Anti-bacterium, antiviral and sensitive microbial, particularly have obvious inhibitory action to staphylococcus, Hemolytic streptococcus, micrococcus gonococcus, diphtheria corynebacterium, Bacillus typhi, dysentery bacterium, influenza virus, Orphan virus, hepatitis B virus, poliovirus, ameba, trichomonas vaginitis, schistosomicide and leptospira.

Rhizoma Coptidis bitter in the mouth, cold in nature; GUIXIN, stomach, liver, large intestine channel.There is heat clearing and damp drying, the effect of removing toxic substances of purging heat.Rhizoma Coptidis containing multiple alkaloid, mainly berberine, also known as berberine, has the pharmacologically actives such as antibacterial, antitumor and arrhythmia, has effect of heat clearing and damp drying, eliminating fire and detoxication.

Radix Glycyrrhizae, sweet in the mouth, property is put down; GUIXIN, spleen, lung, stomach warp.There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, effect of coordinating the actions of various ingredients in a prescription.There is removing toxic substances, eliminate the phlegm, pain relieving, spasmolytic is so that the pharmacological action such as anticancer.

Delayed encephalopathy after acute carbon monoxide poisoning belongs to the category such as Chinese medicine " dementia ", " forgetful ", and qi depression to blood stasis, key network impatency are its pathogenesis; Simultaneously because carbon monoxide poisoning is that foul poison injures QI and blood, the clear key of impatency, cause qi and blood stagnation.The brain being the house of mentality, must cause brains deficient for a long time.Therefore treatment is when with the principle following deficiency syndrome should be treated by tonifying method, sthenia syndrome requiring purgation, with blood circulation promoting and blood stasis dispelling, tonifying kidneys and nourishing brain for rule for the treatment of, treating both the principal and secondary aspects of a disease, with dissipating blood stasis blood, logical brain key, invigorating the liver and kidney.

Fang Zhong, the Radix Polygoni Multiflori, Herba Taxilli can nourish blood the liver benefiting, tonifying kidneys and nourishing brain, muscle reinforcing and bone strengthening, thus reach hemopoietic function in reinforcement, improve the object of human immune system's immunity; The withered trailing plants in ground, Fructus Amomi, Rhizoma Polygonati Odorati energy nourishing YIN and moistening the lung, stomach function regulating spleen invigorating, lowering the adverse-rising QI to resolve phlegm, reach the effect of conditioning human body internal organs and antiinflammatory sterilization; Fructus Hedychii Spicati leaf, Radix Salviae Miltiorrhizae, Semen Persicae, Rhizoma Chuanxiong energy blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, unfold brain key, increase the blood flow of heart and brain, improve microcirculation, improve the symptom such as brain tissue ischemia, anoxia; Herba Menthae, Fructus Forsythiae, Radix Isatidis, Rhizoma Coptidis, Radix Et Rhizoma Rhei energy heat clearing and damp drying, removing toxic substances of purging heat, reaches the object of toxic dampness and heat in removing body, antiinflammatory sterilization.Radix Glycyrrhizae can invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, again can coordinating the actions of various ingredients in a prescription, holds concurrently as making medicine.All medicines share, and play the effect of kidney-supplementing liver-boosting, Fructus Alpiniae Oxyphyllae refreshment, blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing altogether, can strengthen body immune mechanism, improve rapidly the symptom such as brain tissue ischemia, anoxia, accelerate the regeneration of brain cell and the recovery of brain function.

For investigating clinical efficacy and the safety of medicine of the present invention further, we have selected 60 routine patients and carry out clinical treatment.Wherein man 32 example, female 28 example, more than 60 years old 12 example, 40 ~ 59 years old 18 example, 20 ~ 39 years old 20 example, less than 10 years old 10 example.All patients is poisoning all has stupor, poisoning stupor shortest time 1 hour afterwards, the longest 48 hours.All patients are divided into treatment group and each 30 examples of matched group at random.The aspects such as two groups of patient ages, sex, severity extent, site of pathological change and orders of severity compare not statistically significant.

Clinical manifestation:

(1) disturbance of intelligence.Based on dementia, performance memory in various degree, computing power, faculty of understanding, orientation force go down or obstacle, and language and body activity reduce, silent, can be routine in stuporous state 22 time serious.

(2) extrapyramidal system dysfunction.Most patients performance Zhen Chan Ma Paralysis, has a dull expression on one's face, does not laugh at, mask face, flurried, not obvious 16 examples of static tremor.

(3) mental symptom.Comprise behavior strange, cry and laugh by turns, without any apparent reason easily enrage, bipolar and various hallucination 19 example.

(4) decortical syndrome.Cerebral white matter damages extensively with serious thus, and the impulsion having caused cerebral cortex neurons can not spread out of, and is in inhibitory state widely, and brain stem neural impulse up biography place is impaired, and people is in decortical state 2 example.

(5) focal neurologic impairment be that hemisphere white matter Inner has focal damage focus, or hemisphere cortex has focal damage focus.Comprise 1 examples such as sensory deprivation, cortex be blind.

Criterion of therapeutical effect:

Cure: clinical symptoms, sign disappear, recover sick front working and learning, without delayed encephalopathy after acute carbon monoxide poisoning and various sequela;

Effective: cardinal symptom, sign disappear, life is taken care of oneself substantially, does not resume work and learns, can occur delayed encephalopathy after acute carbon monoxide poisoning or sequela;

Effective: cardinal symptom alleviates, sign takes a turn for the better, and life still can not be taken care of oneself, and does not resume work and learns, occurring delayed encephalopathy after acute carbon monoxide poisoning sequela;

Invalid: disturbance of consciousness, symptom and sign are substantially the same or be not improved, and fail to respond to any medical treatment

Therapeutic Method:

Treatment group takes Chinese medicine composition of the present invention, get withered trailing plants 16 grams, 16 grams, Fructus Hedychii Spicati leaf, Herba Menthae 8 grams, Radix Salviae Miltiorrhizae 8 grams, Rhizoma Polygonati Odorati 8 grams, Rhizoma Chuanxiong 10 grams, the Radix Polygoni Multiflori 10 grams, Fructus Forsythiae 9 grams, Fructus Amomi 9 grams, 12 grams, Semen Persicae, Radix Isatidis 16 grams, Herba Taxilli 10 grams, Radix Et Rhizoma Rhei 16 grams, Rhizoma Coptidis 16 grams, 8 grams, Radix Glycyrrhizae, be decocted in water for oral dose, every day 2 times sooner or later.Matched group adopts naloxone (Fourth Ring, Beijing pharmaceutical factory produces, the accurate word H20055760 of traditional Chinese medicines), and 4 ~ 12mg dissolves in 5% glucose or normal saline 250 ~ 500mL, every day 3 times or continuous intravenous dripping.Two groups was all 1 course for the treatment of with 20 days, treated 2 courses for the treatment of all continuously.

Therapeutic outcome:

1, clinical efficacy result:

After treatment, treatment group cures 13 examples, effective 10 examples, effective 6 examples, invalid 1 example, and cure rate is 43.3%, effective percentage 96.7%; Matched group cures 6 examples, effective 9 examples, effective 10 examples, invalid 5 examples, cure rate 20.0, effective percentage 83.3%; Treatment group cure rate and effective percentage are apparently higher than matched group, and through statistical analysis, group difference compares significance (P < 0.05), has comparability.Detailed results is in table 1.

Table 1: the curative effect comparision result after two groups of case treatments

Group	Number of cases	Cure n (%)	Effective n (%)	Effective n (%)	Invalid n (%)	Total effective rate (%)
							Treatment group	30	13(43.3)	10(33.3)	6(20.0)	1(3.3)	96.7
Matched group	30	6(20.0)	9(30.0)	10(33.3)	5(16.7)	83.3

Clinical observation result confirms, Chinese medicine composition of the present invention can significantly improve patient's cure rate in treatment delayed encephalopathy after acute carbon monoxide poisoning, there is the advantages such as instant effect, short treating period, cure rate and effective percentage are high compared with traditional therapy, clinic promotion and application.

Detailed description of the invention

Embodiment 1: a kind of Chinese medicine composition for the treatment of delayed encephalopathy after acute carbon monoxide poisoning, choose withered trailing plants 10 grams, 10 grams, Fructus Hedychii Spicati leaf, Herba Menthae 5 grams, Radix Salviae Miltiorrhizae 5 grams, Rhizoma Polygonati Odorati 5 grams, Rhizoma Chuanxiong 8 grams, the Radix Polygoni Multiflori 8 grams, Fructus Forsythiae 8 grams, Fructus Amomi 8 grams, 8 grams, Semen Persicae, Radix Isatidis 10 grams, Herba Taxilli 8 grams, Radix Et Rhizoma Rhei 10 grams, Rhizoma Coptidis 10 grams, 5 grams, Radix Glycyrrhizae.

Embodiment 2: a kind of Chinese medicine composition for the treatment of delayed encephalopathy after acute carbon monoxide poisoning, choose withered trailing plants 12 grams, 12 grams, Fructus Hedychii Spicati leaf, Herba Menthae 6 grams, Radix Salviae Miltiorrhizae 6 grams, Rhizoma Polygonati Odorati 6 grams, Rhizoma Chuanxiong 9 grams, the Radix Polygoni Multiflori 9 grams, Fructus Forsythiae 9 grams, Fructus Amomi 9 grams, 10 grams, Semen Persicae, Radix Isatidis 12 grams, Herba Taxilli 9 grams, Radix Et Rhizoma Rhei 12 grams, Rhizoma Coptidis 12 grams, 6 grams, Radix Glycyrrhizae.

Embodiment 3: a kind of Chinese medicine composition for the treatment of delayed encephalopathy after acute carbon monoxide poisoning, choose withered trailing plants 14 grams, 14 grams, Fructus Hedychii Spicati leaf, Herba Menthae 7 grams, Radix Salviae Miltiorrhizae 7 grams, Rhizoma Polygonati Odorati 7 grams, Rhizoma Chuanxiong 10 grams, the Radix Polygoni Multiflori 10 grams, Fructus Forsythiae 10 grams, Fructus Amomi 10 grams, 10 grams, Semen Persicae, Radix Isatidis 14 grams, Herba Taxilli 10 grams, Radix Et Rhizoma Rhei 14 grams, Rhizoma Coptidis 14 grams, 7 grams, Radix Glycyrrhizae.

Embodiment 4: a kind of Chinese medicine composition for the treatment of delayed encephalopathy after acute carbon monoxide poisoning, choose withered trailing plants 16 grams, 16 grams, Fructus Hedychii Spicati leaf, Herba Menthae 8 grams, Radix Salviae Miltiorrhizae 8 grams, Rhizoma Polygonati Odorati 8 grams, Rhizoma Chuanxiong 10 grams, the Radix Polygoni Multiflori 10 grams, Fructus Forsythiae 9 grams, Fructus Amomi 9 grams, 12 grams, Semen Persicae, Radix Isatidis 16 grams, Herba Taxilli 10 grams, Radix Et Rhizoma Rhei 16 grams, Rhizoma Coptidis 16 grams, 8 grams, Radix Glycyrrhizae.

Embodiment 5: a kind of Chinese medicine composition for the treatment of delayed encephalopathy after acute carbon monoxide poisoning, choose withered trailing plants 18 grams, 18 grams, Fructus Hedychii Spicati leaf, Herba Menthae 9 grams, Radix Salviae Miltiorrhizae 9 grams, Rhizoma Polygonati Odorati 9 grams, Rhizoma Chuanxiong 11 grams, the Radix Polygoni Multiflori 11 grams, Fructus Forsythiae 11 grams, Fructus Amomi 11 grams, 13 grams, Semen Persicae, Radix Isatidis 18 grams, Herba Taxilli 11 grams, Radix Et Rhizoma Rhei 18 grams, Rhizoma Coptidis 18 grams, 9 grams, Radix Glycyrrhizae.

Embodiment 6: a kind of Chinese medicine composition for the treatment of delayed encephalopathy after acute carbon monoxide poisoning, choose withered trailing plants 20 grams, 20 grams, Fructus Hedychii Spicati leaf, Herba Menthae 10 grams, Radix Salviae Miltiorrhizae 10 grams, Rhizoma Polygonati Odorati 10 grams, Rhizoma Chuanxiong 12 grams, the Radix Polygoni Multiflori 12 grams, Fructus Forsythiae 12 grams, Fructus Amomi 12 grams, 15 grams, Semen Persicae, Radix Isatidis 20 grams, Herba Taxilli 12 grams, Radix Et Rhizoma Rhei 20 grams, Rhizoma Coptidis 20 grams, 10 grams, Radix Glycyrrhizae.

Below by concrete case, Chinese medicine composition curative effect of the present invention is verified further:

Case 1

Patient, female, 51 years old.Patient causes stupor 9 hours due to careless carbon monoxide poisoning, and revive in local hospital treatment, electroencephalogram shows: the abnormal EEG/BEAM of moderate, does not do and checks further and treatment, gives that piracetam is oral advises it to go home to have a rest.After going home, patient is without other Novel presentations except spirit is slightly poor, can normally work and have a rest.After leaving hospital 15 days, patient successively occurs that talking nonsense, behavior are strange, trembling of limbs, limitation of activity, be unable to leave the bed, aphasia, gatism.Under friend recommendation, go to a doctor in here, observe patients symptomatic, be diagnosed as delayed encephalopathy after acute carbon monoxide poisoning, get withered trailing plants 16 grams, 16 grams, Fructus Hedychii Spicati leaf, Herba Menthae 8 grams, Radix Salviae Miltiorrhizae 8 grams, Rhizoma Polygonati Odorati 8 grams, Rhizoma Chuanxiong 10 grams, the Radix Polygoni Multiflori 10 grams, Fructus Forsythiae 9 grams, Fructus Amomi 9 grams, 12 grams, Semen Persicae, Radix Isatidis 16 grams, Herba Taxilli 10 grams, Radix Et Rhizoma Rhei 16 grams, Rhizoma Coptidis 16 grams, 8 grams, Radix Glycyrrhizae, take after decocting, every day 2 times, after 1 course for the treatment of, patient can be reversal, can defecation voluntarily, basic energy talk, can short distance hold up thing to walk, limb tremor disappears, and tension force is not high.After 1 course for the treatment of of continual cure, patient recovers normal substantially, clinical cure.Follow up a case by regular visits to and have no recurrence half a year.

Case 2

Patient, man, 49 years old.This patient uses charcoal fire night in airtight coal stove room, causes carbon monoxide poisoning, gives oxygen uptake, refreshment, brain of living, prevents and treats the treatments such as cerebral edema through local hospital, after revive, consciousness turns clear.After leaving hospital one month, start to occur that memory, faculty of understanding, cognitive power, computing power Progressive symmetric erythrokeratodermia decline, apathetic expression, is developed to defecation from accidental urinary incontinence and does not know, hands interruption does not independently grasp.Engender the symptom such as bradykinesia, astasia, both hands static tremor, athetosis, festination, so go to a doctor in here under friend recommendation.Observe patients symptomatic, be diagnosed as delayed encephalopathy after acute carbon monoxide poisoning, get withered trailing plants 20 grams, 20 grams, Fructus Hedychii Spicati leaf, Herba Menthae 10 grams, Radix Salviae Miltiorrhizae 10 grams, Rhizoma Polygonati Odorati 10 grams, Rhizoma Chuanxiong 12 grams, the Radix Polygoni Multiflori 12 grams, Fructus Forsythiae 12 grams, Fructus Amomi 12 grams, 15 grams, Semen Persicae, Radix Isatidis 20 grams, Herba Taxilli 12 grams, Radix Et Rhizoma Rhei 20 grams, Rhizoma Coptidis 20 grams, 10 grams, Radix Glycyrrhizae, take after decocting, every day 2 times, after 1 course for the treatment of, patient's memory, faculty of understanding, cognitive power, computing power obviously improve, trick energy self control, after continuing to take 1 course for the treatment of, patient recovers orthobiosis substantially, clinical cure.Follow up a case by regular visits to and have no recurrence half a year.

Case 3

Patient, female, 37 years old.Indoor airtight heating in patient's winter before 1 first quarter moon causes carbon monoxide poisoning, rescues consciousness recovery after 5 hours, engender improper symptom after first quarter moon of leaving hospital by local hospital, such as weep in each other's arms, anorexia, dull, seal language, sluggishness etc., cognitive power starts to decline, suspected of poisoning sequela.So recommend to take Drug therapy of the present invention through people, observe patients symptomatic, be diagnosed as delayed encephalopathy after acute carbon monoxide poisoning, get withered trailing plants 10 grams, 10 grams, Fructus Hedychii Spicati leaf, Herba Menthae 5 grams, Radix Salviae Miltiorrhizae 5 grams, Rhizoma Polygonati Odorati 5 grams, Rhizoma Chuanxiong 8 grams, the Radix Polygoni Multiflori 8 grams, Fructus Forsythiae 8 grams, Fructus Amomi 8 grams, 8 grams, Semen Persicae, Radix Isatidis 10 grams, Herba Taxilli 8 grams, Radix Et Rhizoma Rhei 10 grams, Rhizoma Coptidis 10 grams, 5 grams, Radix Glycyrrhizae, take after decocting, every day 2 times, after 1 course for the treatment of, Patients ' Cognitive power is obviously improved, trick energy self control, emotion tends towards stability gradually, after continuing to take 1 course for the treatment of, patient recovers orthobiosis substantially, clinical cure.Follow up a case by regular visits to and have no recurrence half a year.

Claims

1. treat a Chinese medicine composition for delayed encephalopathy after acute carbon monoxide poisoning, it is characterized in that, described Chinese medicine composition is made up of the Chinese medicine of following weight portion:

2. Chinese medicine composition according to claim 1, is characterized in that, described Chinese medicine composition is made up of the Chinese medicine of following weight portion:

3. Chinese medicine composition according to claim 1, is characterized in that, described Chinese medicine composition is made up of the Chinese medicine of following weight portion:

4. Chinese medicine composition according to claim 1, is characterized in that, described Chinese medicine composition is made up of the Chinese medicine of following weight portion:

5. Chinese medicine composition according to claim 1, is characterized in that, described Chinese medicine composition is made up of the Chinese medicine of following weight portion:

6. Chinese medicine composition according to claim 1, is characterized in that, described Chinese medicine composition is made up of the Chinese medicine of following weight portion:

7. Chinese medicine composition according to claim 1, is characterized in that, described Chinese medicine composition is made up of the Chinese medicine of following weight portion: