CN104906423A - Traditional Chinese medicine composition for treating chronic nephritis - Google Patents

Traditional Chinese medicine composition for treating chronic nephritis Download PDF

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CN104906423A
CN104906423A CN201510348361.XA CN201510348361A CN104906423A CN 104906423 A CN104906423 A CN 104906423A CN 201510348361 A CN201510348361 A CN 201510348361A CN 104906423 A CN104906423 A CN 104906423A
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parts
radix
herba
chinese medicine
medicine composition
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包晓娜
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Abstract

The invention discloses a traditional Chinese medicine composition for treating chronic nephritis. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicinal materials in parts by weight: 5-25 parts of uncaria, 10-30 parts of apocynum venetum, 10-40 parts of acanthopanax, 10-40 parts of oyster, 10-40 parts of radix rehmanniae recen, 10-30 parts of radix scrophulariae, 5-25 parts of moutan bark, 5-20 parts of radix paeoniae alba, 10-30 parts of rust-brown crotalaria, 10-30 parts of salviae miltiorrhizae, 5-20 parts of flowers carthami, 10-30 parts of garden burnet, 2-8 parts of pseudo-ginseng, 5-25 parts of hairyvein agrimony, 10-30 parts of rhizoma nelumbinis, 5-25 parts of madder, 10-30 parts of herba cepbalanoplosis segeti, 10-30 parts of lalang grass rhizome, 10-30 parts of dandelion, 5-25 parts of patrinia, 5-20 parts of honeysuckle stem and 5-15 parts of liquorice. The traditional Chinese medicine composition disclosed by the invention has the efficacies of nourishing the kidneys, nourishing the liver, benefiting qi, tonifying the spleen, clearing away heat and toxic materials, and inducing diuresis to alleviate edema, and is significant in curative effect on chronic nephritis, and reliable in action.

Description

A kind of Chinese medicine composition for the treatment of chronic nephritis
Technical field
The present invention relates to a kind of pharmaceutical product not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of chronic nephritis.
Background technology
Chronic nephritis full name chronic glomerulonephritis is one of comparatively common chronic diseases of urinary system, be the ANOMALOUS VARIATIONS of urinating is master, disease sees edema, oliguria, the hematuria that degree is different, or see polyuria, but being night very, a kind of disease of the cardinal symptoms such as waist is miserable, dizzy, weak.At present, anti-inflammation to the main method for the treatment of of chronic nephritis clinically, simple western medical treatment method is hormone, dialysis, kidney transplantation, but the rejection etc. of the dependency that inevitably easily occurs hormone and side effect, Complication of dialysis and renal transplantation is had at therapeutic process, and due to medical expense costliness, a lot of patient, due to family's difficulty, unablely bears medical expense.
Chronic nephritis belongs to the traditional Chinese medical science " edema " and " asthenia " category.The traditional Chinese medical science is thought, chronic nephritis many because of nephropathy with the passing of time, healthy energy is gradually empty, edema delay do not move back; Or luring to edema recurrent exerbation because of reasons such as overstrain, flu, diet, spleen kidney regulates aqueous functional fluid not normal, and causes cold-damp impairment of YANG, and spleen kidney is impaired.
According to theory of Chinese medical science, for the pathogeny of chronic nephritis, with nourishing kidney spleen invigorating, inducing diuresis to remove edema for the rule for the treatment of, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
Have that drug dependence is strong, side effect deficiency greatly, costly to overcome existing clinical treatment chronic nephritis, the invention provides a kind of prepare easy, cost is low, evident in efficacy, the Chinese medicine composition for the treatment of chronic nephritis that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of chronic nephritis, it is characterized in that: its raw material of Chinese medicine and weight are: Ramulus Uncariae Cum Uncis 5-25 part, Herba Apocyni veneti 10-30 part, Radix Et Caulis Acanthopanacis Senticosi 10-40 part, Concha Ostreae 10-40 part, Radix Rehmanniae 10-40 part, Radix Scrophulariae 10-30 part, Cortex Moutan 5-25 part, Radix Paeoniae Alba 5-20 part, Herba Crotalariae Ferrugineae 10-30 part, Radix Salviae Miltiorrhizae 10-30 part, Flos Carthami 5-20 part, Radix Sanguisorbae 10-30 part, Radix Notoginseng 2-8 part, Herba Agrimoniae 5-25 part, Nodus Nelumbinis Rhizomatis 10-30 part, Radix Rubiae 5-25 part, Herba Cirsii 10-30 part, Rhizoma Imperatae 10-30 part, Herba Taraxaci 10-30 part, Herba Patriniae 5-25 part, Caulis Lonicerae 5-20 part, Radix Glycyrrhizae 5-15 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of chronic nephritis, is characterized in that: its raw material of Chinese medicine and weight are: Ramulus Uncariae Cum Uncis 15 parts, Herba Apocyni veneti 20 parts, Radix Et Caulis Acanthopanacis Senticosi 30 parts, Concha Ostreae 30 parts, Radix Rehmanniae 30 parts, Radix Scrophulariae 20 parts, Cortex Moutan 15 parts, the Radix Paeoniae Alba 12 parts, Herba Crotalariae Ferrugineae 20 parts, Radix Salviae Miltiorrhizae 20 parts, 10 parts, Flos Carthami, Radix Sanguisorbae 20 parts, Radix Notoginseng 5 parts, Herba Agrimoniae 15 parts, Nodus Nelumbinis Rhizomatis 20 parts, 15 parts, Radix Rubiae, Herba Cirsii 20 parts, Rhizoma Imperatae 20 parts, Herba Taraxaci 20 parts, Herba Patriniae 15 parts, Caulis Lonicerae 12 parts, 10 parts, Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription.In Chinese medicine composition of the present invention: Ramulus Uncariae Cum Uncis has effect of heat clearing away suppressing the hyperactive liver, relieving spasm by subduing liver-wind; Herba Apocyni veneti has effect of heat clearing away suppressing the hyperactive liver, inducing diuresis to remove edema; Radix Et Caulis Acanthopanacis Senticosi has effect of replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization; Concha Ostreae has the astringent or styptic treatment for spontaneous sweating effect of suppressing the hyperactive liver and subsiding YANG, tranquillizing the mind by relieving convulsion, hard masses softening and resolving, convergence; Radix Rehmanniae has effect of clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, pain relieving regulating menstruation; Radix Scrophulariae has effect of removing heat from blood YIN nourishing, eliminating fire and detoxication; Cortex Moutan has effect of clearing away heat and cooling blood, promoting blood circulation to remove blood stasis; The Radix Paeoniae Alba has effect of nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing receipts antiperspirant; Herba Crotalariae Ferrugineae has nourishing the kidney and liver ,relieving cough and asthma ,effect of eliminating damp, detoxifying; Radix Salviae Miltiorrhizae has effect of promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind; Flos Carthami has effect of promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain; Radix Sanguisorbae has effect of cooling blood for hemostasis, heat-clearing and toxic substances removing, detumescence sore; Radix Notoginseng has effect of activating blood and removing stasis, hemostasis, reducing swelling and alleviating pain; Herba Agrimoniae has effect of astringing to arrest bleeding, stomach invigorating preventing the attack (or recurrence) of malaria, detoxification sore treatment; Nodus Nelumbinis Rhizomatis has effect of hemostasis dissipating blood stasis; Effect that Radix Rubiae has cooling blood for hemostasis, blood stasis dispelling is stimulated the menstrual flow; Herba Cirsii has effect of cooling blood for hemostasis, removing blood stasis to reduce swelling; Rhizoma Imperatae has effect of cooling blood for hemostasis, clearing away heat and promoting diuresis; Herba Taraxaci has heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, effect of inducing diuresis for treating stranguria syndrome; Herba Patriniae has effect of heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, stasis-dispelling and pain-killing; Caulis Lonicerae has effect of heat-clearing and toxic substances removing, dispelling wind dredging collateral; Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.The selected medicament composing prescription of the present invention, its drug component, through dialectical compatibility, helps using mutually assistant, plays effect of nourishing the kidney and liver, replenishing QI to invigorate the spleen, heat-clearing and toxic substances removing, inducing diuresis to remove edema altogether, reach treating both the principal and secondary aspects of a disease to the treatment of chronic nephritis.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopts the use that is decocted in water for oral dose.Through clinical practice checking, it is reliably evident in efficacy, mild in medicine property and, do not occur toxic and side effects, effective percentage reaches 93%, cure rate 60%.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
Treat a Chinese medicine composition for chronic nephritis, its raw material of Chinese medicine and weight proportion are: Ramulus Uncariae Cum Uncis 15g, Herba Apocyni veneti 20g, Radix Et Caulis Acanthopanacis Senticosi 30g, Concha Ostreae 30g, Radix Rehmanniae 30g, Radix Scrophulariae 20g, Cortex Moutan 15g, Radix Paeoniae Alba 12g, Herba Crotalariae Ferrugineae 20g, Radix Salviae Miltiorrhizae 20g, Flos Carthami 10g, Radix Sanguisorbae 20g, Radix Notoginseng 5g, Herba Agrimoniae 15g, Nodus Nelumbinis Rhizomatis 20g, Radix Rubiae 15g, Herba Cirsii 20g, Rhizoma Imperatae 20g, Herba Taraxaci 20g, Herba Patriniae 15g, Caulis Lonicerae 12g, Radix Glycyrrhizae 10g.
Embodiment 2
Treat a Chinese medicine composition for chronic nephritis, its raw material of Chinese medicine and weight proportion are: Ramulus Uncariae Cum Uncis 10g, Herba Apocyni veneti 25g, Radix Et Caulis Acanthopanacis Senticosi 15g, Concha Ostreae 40g, Radix Rehmanniae 10g, Radix Scrophulariae 30g, Cortex Moutan 5g, Radix Paeoniae Alba 15g, Herba Crotalariae Ferrugineae 10g, Radix Salviae Miltiorrhizae 25g, Flos Carthami 12g, Radix Sanguisorbae 30g, Radix Notoginseng 4g, Herba Agrimoniae 25g, Nodus Nelumbinis Rhizomatis 10g, Radix Rubiae 20g, Herba Cirsii 15g, Rhizoma Imperatae 25g, Herba Taraxaci 10g, Herba Patriniae 20g, Caulis Lonicerae 5g, Radix Glycyrrhizae 12g.
Embodiment 3
Treat a Chinese medicine composition for chronic nephritis, its raw material of Chinese medicine and weight proportion are: Ramulus Uncariae Cum Uncis 20g, Herba Apocyni veneti 10g, Radix Et Caulis Acanthopanacis Senticosi 25g, Concha Ostreae 15g, Radix Rehmanniae 40g, Radix Scrophulariae 10g, Cortex Moutan 25g, Radix Paeoniae Alba 10g, Herba Crotalariae Ferrugineae 25g, Radix Salviae Miltiorrhizae 15g, Flos Carthami 20g, Radix Sanguisorbae 10g, Radix Notoginseng 8g, Herba Agrimoniae 5g, Nodus Nelumbinis Rhizomatis 30g, Radix Rubiae 10g, Herba Cirsii 25g, Rhizoma Imperatae 15g, Herba Taraxaci 30g, Herba Patriniae 10g, Caulis Lonicerae 20g, Radix Glycyrrhizae 5g.
Embodiment 4
Treat a Chinese medicine composition for chronic nephritis, its raw material of Chinese medicine and weight proportion are: Ramulus Uncariae Cum Uncis 5g, Herba Apocyni veneti 30g, Radix Et Caulis Acanthopanacis Senticosi 10g, Concha Ostreae 25g, Radix Rehmanniae 15g, Radix Scrophulariae 25g, Cortex Moutan 10g, Radix Paeoniae Alba 20g, Herba Crotalariae Ferrugineae 15g, Radix Salviae Miltiorrhizae 30g, Flos Carthami 5g, Radix Sanguisorbae 15g, Radix Notoginseng 6g, Herba Agrimoniae 10g, Nodus Nelumbinis Rhizomatis 25g, Radix Rubiae 5g, Herba Cirsii 30g, Rhizoma Imperatae 10g, Herba Taraxaci 25g, Herba Patriniae 5g, Caulis Lonicerae 15g, Radix Glycyrrhizae 8g.
Embodiment 5
Treat a Chinese medicine composition for chronic nephritis, its raw material of Chinese medicine and weight proportion are: Ramulus Uncariae Cum Uncis 25g, Herba Apocyni veneti 15g, Radix Et Caulis Acanthopanacis Senticosi 40g, Concha Ostreae 10g, Radix Rehmanniae 25g, Radix Scrophulariae 15g, Cortex Moutan 25g, Radix Paeoniae Alba 5g, Herba Crotalariae Ferrugineae 30g, Radix Salviae Miltiorrhizae 10g, Flos Carthami 15g, Radix Sanguisorbae 25g, Radix Notoginseng 2g, Herba Agrimoniae 20g, Nodus Nelumbinis Rhizomatis 15g, Radix Rubiae 25g, Herba Cirsii 10g, Rhizoma Imperatae 30g, Herba Taraxaci 15g, Herba Patriniae 25g, Caulis Lonicerae 10g, Radix Glycyrrhizae 15g.
Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and covers powder, soaks 15 ~ 20 minutes, then adds water and do not have powder about 6 centimetres, carries out first time to decoct, and adopts intense fire to decoct, with slow fire boiling 20 ~ 30 minutes after boiling at a simmer; Second time decocts, and adds water and does not have powder about 4 centimetres, decocts 15 ~ 20 minutes after water boils.Decoct extracting juice twice, merge.
The present invention, with a kind of Chinese medicine composition for the treatment of chronic nephritis given by embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: this Chinese medicine composition is applied to clinical observation case 100 example, man 64 example, female 36 example, 30 ~ 75 years old age.
Two, diagnostic criteria: the diagnostic criteria with reference to the national academic conference revision of Nanjing the 2nd, nephropathy association of China in 1985:
(1), onset is slow, protracted inflammation, time light time heavy, renal function is faded, and the later stage can occur anemia, electrolyte disturbance, the situations such as blood urea nitrogen, serum creatinine rising;
(2) performances such as albuminuria in various degree, hematuria, edema and hypertension, are had;
(3), acute attack can be brought out because of reasons such as respiratory tract infection in the state of an illness, occur the performance of similar acute nephritis, also have some cases can have the automatic catabasis.
Three, usage and dosage: during clinical practice, potion on the one, decocting twice extracting juice is about 400ml, point morning, late twice empty stomach decoction being taken warmly.It within ten days, is a course for the treatment of.
Four, criterion of therapeutical effect:
(1), cure: clinical symptom disappearance, laboratory checking index is normal;
(2), effective: clinical symptoms is clearly better, and laboratory checking index is clearly better;
(3), effectively: clinical symptoms takes a turn for the better, laboratory checking index takes a turn for the better;
(4), invalid: clinical symptoms, lab index are all without improvement.
Five, therapeutic effect: in this clinical observation case, takes medicine 2-15 the course for the treatment of, and recovery from illness 60 example, follows up a case by regular visits to and have no recurrence; Effective 19 examples, effective 13 examples, invalid 8 examples.There is not toxic and side effects in treatments period.
Six, model case:
Case 1: Cui, female, 37 years old.Suffer from chronic nephritis 1 year, disease is seen: lusterless complexion is dark and gloomy, and weak breath is weak, defecates partially rare, poor appetite abdominal distention, tastelessness and no thirst, soreness of waist and knee joint, and hands and feet being not warm, nocturia, pale tongue secretly has indentation, deep and hesitant pulse.Take 5 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, weak breath is weak, and the symptom such as to defecate partially rare disappears substantially, occasionally has soreness of waist and knee joint; Continue to take 3 courses for the treatment of, all symptoms disappear completely, cure.
Case 2: Tan, man, 53 years old.Patient is edema of pair of lower extremities since 2 months, and companion's soreness of waist, weak, hospital diagnosis is: chronic nephritis.Through local hospital treatment, edema disappears, and after leaving hospital, whenever after diseases caused by exogenous pathogenic factor or fatigue, namely edema is sent out, and symptom recurrence is recently serious.Take medicament 4 course for the treatment of prepared by Chinese medicine composition of the present invention, the soreness of waist, weak transference cure, edema of lower limbs obviously alleviates; Continue to take 5 courses for the treatment of, anasarca symptom disappears.Urine examination is normal, follows up a case by regular visits to and has no recurrence half a year.

Claims (2)

1. treat the Chinese medicine composition of chronic nephritis for one kind, it is characterized in that: its raw material of Chinese medicine and weight are: Ramulus Uncariae Cum Uncis 5-25 part, Herba Apocyni veneti 10-30 part, Radix Et Caulis Acanthopanacis Senticosi 10-40 part, Concha Ostreae 10-40 part, Radix Rehmanniae 10-40 part, Radix Scrophulariae 10-30 part, Cortex Moutan 5-25 part, Radix Paeoniae Alba 5-20 part, Herba Crotalariae Ferrugineae 10-30 part, Radix Salviae Miltiorrhizae 10-30 part, Flos Carthami 5-20 part, Radix Sanguisorbae 10-30 part, Radix Notoginseng 2-8 part, Herba Agrimoniae 5-25 part, Nodus Nelumbinis Rhizomatis 10-30 part, Radix Rubiae 5-25 part, Herba Cirsii 10-30 part, Rhizoma Imperatae 10-30 part, Herba Taraxaci 10-30 part, Herba Patriniae 5-25 part, Caulis Lonicerae 5-20 part, Radix Glycyrrhizae 5-15 part.
2. a kind of Chinese medicine composition for the treatment of chronic nephritis according to claim 1, is characterized in that: its raw material of Chinese medicine and weight are: Ramulus Uncariae Cum Uncis 15 parts, Herba Apocyni veneti 20 parts, Radix Et Caulis Acanthopanacis Senticosi 30 parts, Concha Ostreae 30 parts, Radix Rehmanniae 30 parts, Radix Scrophulariae 20 parts, Cortex Moutan 15 parts, the Radix Paeoniae Alba 12 parts, Herba Crotalariae Ferrugineae 20 parts, Radix Salviae Miltiorrhizae 20 parts, 10 parts, Flos Carthami, Radix Sanguisorbae 20 parts, Radix Notoginseng 5 parts, Herba Agrimoniae 15 parts, Nodus Nelumbinis Rhizomatis 20 parts, 15 parts, Radix Rubiae, Herba Cirsii 20 parts, Rhizoma Imperatae 20 parts, Herba Taraxaci 20 parts, Herba Patriniae 15 parts, Caulis Lonicerae 12 parts, 10 parts, Radix Glycyrrhizae.
CN201510348361.XA 2015-06-23 2015-06-23 Traditional Chinese medicine composition for treating chronic nephritis Pending CN104906423A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1419927A (en) * 2001-11-18 2003-05-28 孙燕明 Sieral schemes and Chinese medicine preparation for traditional Chinese medicine diagnosis and treatment of nephritis and nephropathy syndrome
KR20090128119A (en) * 2008-06-10 2009-12-15 (주)유라팜 Juncus effusus extract-containing composition for treating or preventing inflammatory disease or immunological disease

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1419927A (en) * 2001-11-18 2003-05-28 孙燕明 Sieral schemes and Chinese medicine preparation for traditional Chinese medicine diagnosis and treatment of nephritis and nephropathy syndrome
KR20090128119A (en) * 2008-06-10 2009-12-15 (주)유라팜 Juncus effusus extract-containing composition for treating or preventing inflammatory disease or immunological disease

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
马莲湘: "过敏性紫癜伴肾炎", 《浙江中医学院学报》 *

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Application publication date: 20150916