CN104906226A - Traditional Chinese medicine composition for treating insomnia - Google Patents
Traditional Chinese medicine composition for treating insomnia Download PDFInfo
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- CN104906226A CN104906226A CN201510322051.0A CN201510322051A CN104906226A CN 104906226 A CN104906226 A CN 104906226A CN 201510322051 A CN201510322051 A CN 201510322051A CN 104906226 A CN104906226 A CN 104906226A
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Abstract
The invention relates to a traditional Chinese medicine composition and in particular relates to a traditional Chinese medicine composition for treating insomnia. The traditional Chinese medicine composition for treating insomnia is prepared from the following traditional Chinese medicines by weight: 10-15g of radix bupleuri, 15-20g of poria cocos, 5-10g of angelica sinensis, 10-15g of bighead atractylodes rhizome, 20-30g of seeds of wild jujubes, 25-30g of platycladi seeds, 20-30g of salvia miltiorrhiza, 10-15g of fructus ziziphi jujubae, 10-15g of polygala root, 8-10g of fruits of Chinese magnoliavine, 6-10g of platycodon grandiflorum, 6-10g oftuber fleeceflower stem, 8-10g of morinda officinalis, 6-10g of herba epimedii and 5-10g of liquorice.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, more particularly relate to a kind of Chinese medicine composition of Cure for insomnia.
Background technology
Insomnia refers to starting and maintaining generation obstacle of sleep, it is modal sleep disorder, cause the quality of sleep can not meet individual physiological need, main clinical manifestation is difficulty falling asleep, easily wake up after sleeping, have difficulty in going to sleep after waking up, early awakening is with drowsirness, dizzy, headache, lethargy is depressed, extremity fatigue and weak, memory persistence goes down, bradykinesia etc., patient's daytime to some extent self-induction fail fully to have a rest and regain one's vigor, thus body tiredness, lethargy, drowsiness, aprosexia, thinking difficulty, bradykinesia, depressed, anxiety, even nervous, severe patient has increased heart rate, body temperature raises, the autonomic nerve symptoms such as peripheral vessels contraction.Insomnia is one of common clinical disease, though do not belong to critical illness, hinders people orthobiosis, work, study, and can increase the weight of or bring out the diseases such as cardiopalmus, the thoracic obstruction, dizzy, headache, apoplexy, and intractable insomnia, more brings long-term misery to patient.
If the drug main Western medicine of current treatment of insomnia patients, although western medicine insomnia has certain curative effect, its adverse consequences, if the withdrawal symptom after dependency, toleration, toxic and side effects, drug withdrawal and Financial cost etc. are all present insurmountable problems.
Summary of the invention
For above-mentioned Problems existing, the invention provides a kind of evident in efficacy, having no side effect is used for the treatment of the Chinese medicine composition of insomnia.
For achieving the above object, the technical scheme that the present invention takes is, a Chinese medicine composition for Cure for insomnia is made up of the Chinese medicine of following weight proportion: Radix Bupleuri 10-15g, Poria 15--20 g, Radix Angelicae Sinensis 5--10g, Rhizoma Atractylodis Macrocephalae 10--15g, Semen Ziziphi Spinosae 20--30g, Semen Platycladi 25--30g, Radix Salviae Miltiorrhizae 20--30g, Fructus Jujubae 10--15g, Radix Polygalae 10--15g, Fructus Schisandrae Chinensis 8--10g, Radix Platycodonis 6--10g, Caulis Polygoni Multiflori 6--10g, Radix Morindae Officinalis 8--10g, Herba Epimedii 6--10g, Radix Glycyrrhizae 5--10g.
Preferably, a Chinese medicine composition for Cure for insomnia is be made up of the Chinese medicine of following weight proportion: Radix Bupleuri 12g, Poria 18g, Radix Angelicae Sinensis 8g, Rhizoma Atractylodis Macrocephalae 12g, Semen Ziziphi Spinosae 25g, Semen Platycladi 26g, Radix Salviae Miltiorrhizae 25g, Fructus Jujubae 12g, Radix Polygalae 12g, Fructus Schisandrae Chinensis 8g, Radix Platycodonis 8g, Caulis Polygoni Multiflori 8g, Radix Morindae Officinalis 8g, Herba Epimedii 8g, Radix Glycyrrhizae 8g.
Radix Bupleuri: bitter in the mouth, cold nature; Return liver, gallbladder meridian; Have and show in solution, dispersing the stagnated live-QI to relieve the stagnation of QI, effect of elevate a turnable ladder yang-energy.
Poria: sweet in the mouth, light, property is put down; GUIXIN, lung, spleen, kidney channel; There is promoting diuresis to eliminate damp pathogen, spleen invigorating and in, effect of mind tranquilizing and the heart calming.
Radix Angelicae Sinensis: sweet in the mouth, pungent, bitter, warm in nature; Return liver, the heart, spleen channel; Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation.
The Rhizoma Atractylodis Macrocephalae: sweet in the mouth, hardship, warm in nature; Return spleen, stomach warp; There is invigorating the spleen and benefiting QI, dampness diuresis, hidroschesis, antiabortive effect.
Semen Ziziphi Spinosae: sweet in the mouth, acid, property is put down; Return liver, gallbladder, heart channel; There is the tonifying liver that nourishes heart, mind tranquilizing and the heart calming, arresting sweating, the effect of promoting the production of body fluid.
Semen Platycladi: sweet in the mouth, property is put down; GUIXIN, kidney, large intestine channel; There is tranquilizing by nourishing the heart, effect of loosening bowel to relieve constipation.
Radix Salviae Miltiorrhizae: bitter in the mouth, cold nature; GUIXIN, Liver Channel; There is blood circulation promoting and blood stasis dispelling, effect of menstruction regulating and pain relieving.
Fructus Jujubae: sweet in the mouth, warm in nature; Return spleen, stomach warp; There is air making-up and spleen enlivening, nourishing blood to tranquillize the mind, harmonizing yingfen and weifen, relax effect of the property of medicine.
Radix Polygalae: bitter in the mouth, pungent, warm in nature; GUIXIN, kidney, lung meridian; There is mind tranquilizing and the heart calming, expelling phlegm for arresting cough, effect of reducing swelling and alleviating pain.
Fructus Schisandrae Chinensis: sour in the mouth, sweet, warm in nature; Return lung, the heart, kidney channel; There is convergence astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, effect of kidney calming.
Radix Platycodonis: bitter in the mouth, pungent, property is put down; Return lung meridian; There is dispersing lung-QI and dissipating phlegm, sore-throat relieving, effect of evacuation of pus.
Caulis Polygoni Multiflori: sweet in the mouth, property is put down; GUIXIN, Liver Channel; There is nourishing blood to tranquillize the mind, effect of wind dispelling dredging collateral.
Radix Morindae Officinalis: acrid in the mouth, sweet, slightly warm in nature; Return liver, kidney channel; There is kidney-replenishing, bone and muscle strengthening, effect of wind-damp dispelling.
Herba Epimedii: acrid in the mouth, sweet, warm in nature; Return liver, kidney channel; There is kidney invigorating and YANG supporting, effect of expelling wind and removing dampness.
Radix Glycyrrhizae: sweet in the mouth, property is put down; Return spleen, stomach, lung, heart channel; There is QI invigorating invigorating middle warmer, expelling phlegm for arresting cough, heat-clearing and toxic substances removing, relieving spasm to stop pain, effect of coordinating the actions of various ingredients in a prescription.
Chinese medicine composition of the present invention decocting method routinely produces medicament, its concrete grammar is as follows: above-mentioned raw material of Chinese medicine is put into container, add water and do not have powder, soak 15-30 minutes, add water again and do not have powder 5-8 centimetres, carry out first time decoction, decoct with high heat before not boiling, with slow fire boiling 15-30 minutes after boiling; When second time decocts, add water and do not have powder 5-10 centimetres, decoct with high heat, with slow fire boiling 15-25 minutes after water boils; Decoct extracting juice twice, merging is taken.
The present composition has carried out a large amount of clinical trials of a large amount of animal acute toxicity tests, long-term toxicity test for animals and disease therapy, drops into the use link of disease therapy provide science and objective foundation to this medicine.Its result of the test is as follows:
(1) carry out animal acute toxicity test to decoction prepared by the present invention, get white mice 20, male and female have both, body weight 40-60g, hungry 15-20 hours, every only every natural gift were filled with for 3 times and are fed 20-25ml, and continuous irrigation is fed one week, observes 14 days, white mice is movable normal, non-toxic reaction, without dead; Show that oral liquid is without acute toxicity, clinical medicine dose safety.
(2) long-term toxicity test for animals is carried out to decoction prepared by the present invention, get rat 30, male and female have both, body weight 120-150g, be divided into two groups, often organize 15, wherein first group as administration group, feed by filling with for 2 times every every day, each 5-10ml, second group of diet as a control group, once a day, continuous irrigation is fed 100 days, survey body weight, in last administration 24 hours sacrificed by decapitation, survey blood, routine urinalysis, liver function, renal function, core, the internal organs such as kidney, the change of tissues observed form, observe the effect of dosage, observe diet, movable change, experiment proves that administration group compares without significant change with matched group, equal non-toxic reaction, a kind of safe drugs.
The component of this Chinese medicine composition all adopts natural raw material of Chinese medicine, its preparation is easy, medicine source is wide, cost is low, various material medicines in component are coordinated together mutually, can play and farthest play drug effect, effectively can regulate equilibrium between yin and yang and the self-coordination ability of patient's body, there is effect of supplementing QI for promoting the production of body fluid, nourishing blood to tranquillize the mind, kidney calming, thus reach the object for the treatment of both the principal and secondary aspects of a disease; And good absorbing effect, evident in efficacy, have no side effect, safety is high.
Below in conjunction with clinical data and model case, beneficial effect of the present invention is further illustrated.
One, physical data
Carry out clinical observation treatment to 158 routine patients, wherein male patient 75 example, female patient 83 example, at 16-75 years old ages, the course of disease 6 months-6 years, is the insomnia that a variety of causes causes.
Two, Therapeutic Method
Adopt the decoction prepared by Chinese medicine composition of the present invention, every day is sooner or later each once oral, within 5 days, is a course for the treatment of.
Three, efficacy assessment standard
With reference to " new Chinese medicine guideline of clinical investigations " curative effect determinate standard:
Recovery from illness: easily fall asleep or sleep and recover normal, can sleep every night more than 7 hours, subjective symptoms disappears substantially;
Effective: sleep obviously improves, fall asleep comparatively easy, can sleep every night more than 5 hours, subjective symptoms SPR;
Effective: still to fall asleep after treatment, sleep prolongation 2-3 hours, subjective symptoms comparatively before alleviates, or occasionally has slight recurrence;
Invalid: after treatment, sleep state and subjective symptoms have no improvement.
Four, therapeutic outcome
Clinical recovery 147 example, accounts for 93.0%; Effective 6 examples, account for 3.8%; Effective 4 examples, account for 2.5%; Invalid 2 examples, account for 1.2%; Total effective rate 98.7%.
Five, model case
Case 1
Liu, man, 39 years old, patient's private prosecution insomnia and dreamful sleep, cannot sleep soundly, bitter taste in the mouth and dry throat, emotional lability, irritable, and dizzy nauseating, chest is vexed swollen sometimes, hypomnesis, every night time for falling asleep only 2-4 hours.Take medicament 7 days prepared by Chinese medicine composition of the present invention, can go to sleep peacefully, symptom alleviates, and continues again to take 7 days, and all symptoms all disappear, and cures, follows up a case by regular visits to and do not recur for 1 year.
Case 2
Week certain, female, 42 years old, Top Management, daily corporate business is more, often headache in this year, dizzy, feeling of fullness in the head, have difficulty in going to sleep in the evening, and namely a moment of falling asleep wakes up with a start, cardiopalmus after waking up, vexed, can not fall asleep again, sometimes even lie awake all night, initial stage take sleeping pill still can, the later stage, sleeping pill consumption also increased thereupon with insomnia the increasing the weight of of degree, these last few days, takes sleeping pill to no effect, and occurs uncomfortable in chest, the symptom such as cardiopalmus, anorexia.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, difficulty falling asleep symptom is obviously improved, and uncomfortable in chest, the symptom such as cardiopalmus, anorexia alleviates to some extent, continue again to take 3 courses for the treatment of, more than the 7 hours length of one's sleep of every day, and simultaneous phenomenon disappears completely, follows up a case by regular visits to and does not recur for 1 year.
Case 3
Jiang, female, 56 years old, suffers from because work has some setbacks half a year of having a sleepless night, and be difficult to night fall asleep, easily wake up with a start after sleeping, often headache, giddy, feeling of fullness in the head, daytime, lethargy was depressed, listless.Take medicament 5 days prepared by Chinese medicine composition of the present invention, night comparatively fast can enter sleep state, but easily wakes up in sleep, continues again to take 15 days, can go to sleep peacefully, and sleep duration more than 7 hours, the symptom of easily waking up with a start in sleep also obviously reduces thereupon.
Detailed description of the invention
Embodiment 1
A Chinese medicine composition for Cure for insomnia is be made up of the Chinese medicine of following weight proportion: Radix Bupleuri 10g, Poria 15g, Radix Angelicae Sinensis 8g, Rhizoma Atractylodis Macrocephalae 15g, Semen Ziziphi Spinosae 30g, Semen Platycladi 30g, Radix Salviae Miltiorrhizae 30g, Fructus Jujubae 12g, Radix Polygalae 15g, Fructus Schisandrae Chinensis 9g, Radix Platycodonis 10g, Caulis Polygoni Multiflori 8g, Radix Morindae Officinalis 8g, Herba Epimedii 8g, Radix Glycyrrhizae 8g.
Above-mentioned raw material of Chinese medicine is put into container, adds water and do not have powder, soak 15-30 minutes, then add water and do not have powder 5-8 centimetres, carrying out first time decocts, and decocts with high heat, with slow fire boiling 15-30 minutes after boiling before not boiling; When second time decocts, add water and do not have powder 5-10 centimetres, decoct with high heat, with slow fire boiling 15-25 minutes after water boils; Decoct extracting juice twice, merging is taken.
Embodiment 2
A Chinese medicine composition for Cure for insomnia is made up of the Chinese medicine of following weight proportion: Radix Bupleuri 12, Poria 18 g, Radix Angelicae Sinensis 10g, Rhizoma Atractylodis Macrocephalae 14g, Semen Ziziphi Spinosae 30g, Semen Platycladi 30g, Radix Salviae Miltiorrhizae 30g, Fructus Jujubae 15g, Radix Polygalae 12g, Fructus Schisandrae Chinensis 8g, Radix Platycodonis 8g, Caulis Polygoni Multiflori 8g, Radix Morindae Officinalis 8g, Herba Epimedii 9g, Radix Glycyrrhizae 6g.
Above-mentioned raw material of Chinese medicine is put into container, adds water and do not have powder, soak 15-30 minutes, then add water and do not have powder 5-8 centimetres, carrying out first time decocts, and decocts with high heat, with slow fire boiling 15-30 minutes after boiling before not boiling; When second time decocts, add water and do not have powder 5-10 centimetres, decoct with high heat, with slow fire boiling 15-25 minutes after water boils; Decoct extracting juice twice, merging is taken.
Embodiment 3
A Chinese medicine composition for Cure for insomnia is made up of the Chinese medicine of following weight proportion: Radix Bupleuri 14g, Poria 16 g, Radix Angelicae Sinensis 8g, Rhizoma Atractylodis Macrocephalae 14g, Semen Ziziphi Spinosae 25g, Semen Platycladi 30g, Radix Salviae Miltiorrhizae 30g, Fructus Jujubae 12g, Radix Polygalae 12g, Fructus Schisandrae Chinensis 9g, Radix Platycodonis 9g, Caulis Polygoni Multiflori 8g, Radix Morindae Officinalis 8g, Herba Epimedii 9g, Radix Glycyrrhizae 7g.
Above-mentioned raw material of Chinese medicine is put into container, adds water and do not have powder, soak 15-30 minutes, then add water and do not have powder 5-8 centimetres, carrying out first time decocts, and decocts with high heat, with slow fire boiling 15-30 minutes after boiling before not boiling; When second time decocts, add water and do not have powder 5-10 centimetres, decoct with high heat, with slow fire boiling 15-25 minutes after water boils; Decoct extracting juice twice, merging is taken.
Embodiment 4
A Chinese medicine composition for Cure for insomnia is made up of the Chinese medicine of following weight proportion: Radix Bupleuri 12g, Poria 18 g, Radix Angelicae Sinensis 8g, Rhizoma Atractylodis Macrocephalae 12g, Semen Ziziphi Spinosae 25g, Semen Platycladi 25g, Radix Salviae Miltiorrhizae 25g, Fructus Jujubae 15g, Radix Polygalae 15g, Fructus Schisandrae Chinensis 9g, Radix Platycodonis 8g, Caulis Polygoni Multiflori 8g, Radix Morindae Officinalis 9g, Herba Epimedii 9g, Radix Glycyrrhizae 5g.
Above-mentioned raw material of Chinese medicine is put into container, adds water and do not have powder, soak 15-30 minutes, then add water and do not have powder 5-8 centimetres, carrying out first time decocts, and decocts with high heat, with slow fire boiling 15-30 minutes after boiling before not boiling; When second time decocts, add water and do not have powder 5-10 centimetres, decoct with high heat, with slow fire boiling 15-25 minutes after water boils; Decoct extracting juice twice, merging is taken.
Claims (2)
1. the Chinese medicine composition of a Cure for insomnia, it is characterized in that, be made up of the Chinese medicine of following weight proportion: Radix Bupleuri 10-15g, Poria 15--20 g, Radix Angelicae Sinensis 5--10g, Rhizoma Atractylodis Macrocephalae 10--15g, Semen Ziziphi Spinosae 20--30g, Semen Platycladi 25--30g, Radix Salviae Miltiorrhizae 20--30g, Fructus Jujubae 10--15g, Radix Polygalae 10--15g, Fructus Schisandrae Chinensis 8--10g, Radix Platycodonis 6--10g, Caulis Polygoni Multiflori 6--10g, Radix Morindae Officinalis 8--10g, Herba Epimedii 6--10g, Radix Glycyrrhizae 5--10g.
2. the Chinese medicine composition of a kind of Cure for insomnia according to claim 1, it is characterized in that, be made up of the Chinese medicine of following weight proportion: Radix Bupleuri 12g, Poria 18g, Radix Angelicae Sinensis 8g, Rhizoma Atractylodis Macrocephalae 12g, Semen Ziziphi Spinosae 25g, Semen Platycladi 26g, Radix Salviae Miltiorrhizae 25g, Fructus Jujubae 12g, Radix Polygalae 12g, Fructus Schisandrae Chinensis 8g, Radix Platycodonis 8g, Caulis Polygoni Multiflori 8g, Radix Morindae Officinalis 8g, Herba Epimedii 8g, Radix Glycyrrhizae 8g.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105832885A (en) * | 2016-04-29 | 2016-08-10 | 朱增伟 | Traditional Chinese medicine composition for treating insomnia |
| CN106729440A (en) * | 2017-02-06 | 2017-05-31 | 朱增伟 | A kind of Chinese drugs agentia for treating insomnia |
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2015
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Patent Citations (3)
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| CN100998664A (en) * | 2006-12-31 | 2007-07-18 | 柴增胜 | Oral traditional Chinese medicine for treating critical anhypnia of insulfficiency of the spleen-qi type |
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| CN103816332A (en) * | 2013-12-10 | 2014-05-28 | 济南新起点医药科技有限公司 | Traditional Chinese medicine composition for treating insomnia caused by weakness of both heart and spleen |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105832885A (en) * | 2016-04-29 | 2016-08-10 | 朱增伟 | Traditional Chinese medicine composition for treating insomnia |
| CN106729440A (en) * | 2017-02-06 | 2017-05-31 | 朱增伟 | A kind of Chinese drugs agentia for treating insomnia |
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Application publication date: 20150916 |