CN104905967B - Production mould for the double-deck enteric hollow capsule - Google Patents

Production mould for the double-deck enteric hollow capsule Download PDF

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Publication number
CN104905967B
CN104905967B CN201510270072.2A CN201510270072A CN104905967B CN 104905967 B CN104905967 B CN 104905967B CN 201510270072 A CN201510270072 A CN 201510270072A CN 104905967 B CN104905967 B CN 104905967B
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CN
China
Prior art keywords
forming part
mold
softgel shell
double
deck
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Expired - Fee Related
Application number
CN201510270072.2A
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Chinese (zh)
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CN104905967A (en
Inventor
瞿樑
陈云龙
王明霞
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ZHEJIANG YILI CAPSULE Co Ltd
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ZHEJIANG YILI CAPSULE Co Ltd
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Priority to CN201510270072.2A priority Critical patent/CN104905967B/en
Publication of CN104905967A publication Critical patent/CN104905967A/en
Application granted granted Critical
Publication of CN104905967B publication Critical patent/CN104905967B/en
Expired - Fee Related legal-status Critical Current
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Abstract

The present invention discloses a kind of production mould for the double-deck enteric hollow capsule, belong to capsule production equipment field, the mold is assemblied to form using two identical components one, forming part one and forming part two in component one cooperatively form outer softgel shell, forming part two and forming part three cooperatively form interior softgel shell, wherein interior softgel shell and outer softgel shell are formed by the connecting hole in mold connects, after mold assembly is good, pass through the glue pipeline and nozzle injecting glue in upper cover plate, drying and processing, can be obtained be connected and fixed it is interior, outer softgel shell, after mold is dismantled, remove the double-deck softgel shell of preparation, by the way that medicinal powder is added in inside softgel shell, the double-deck enteric hollow capsule is can be obtained into two mutual assembly of bilayer vesicles shell again.Compared with tradition prepares the method for capsulae enterosolubilis, it is filling again to be not required to for medicinal powder to be processed into pellet using this kind of mold, by being directly added into medicinal powder in inside softgel shell, then by two double-deck softgel shell assembly up to required drug, preparation process is simple and convenient, high in machining efficiency.

Description

Production mould for the double-deck enteric hollow capsule
Technical field
The present invention relates to a kind of production mould, in particular to a kind of production mould for the double-deck enteric hollow capsule belongs to In capsule production equipment field.
Background technique
The preparation of conventional capsules includes glue, drying, pulling out the processes such as glue, mold on offset plate immerse after glue glues Drying line drying, then be transferred to from drying line and pull out glue machine, the capsule dried one by one is pulled up by pulling out glue machine, the die of capsule used Specific cylindrical, the head of mold is hemispherical, is being provided with an annular groove on mold head, is using this The capsule that the mold of sample is made just will form bulge loop in its inner cavity at bottom, for after A, B capsule powder charge fitting It mutually blocks, is not easy to deviate from after making A, Type B capsule capping, medicinal powder will not fall out capsule.
This kind of mold is mainly used for the production of plain hollow capsule, and for the double-deck enteric hollow capsule, due to its drug The cyst wall shell that outside needs the anti-gastric juice of one layer of package to destroy, therefore currently used method is that will there is acid or alkalinity medicinal powder to add Work at being filled in corresponding Capsules (softgel shell) or enteric hollow capsule (softgel shell) again after pellet or enteric-coated micro-pill, by micro- The film of ball outer cladding and the inner wall of softgel shell separate, this kind of method needs medicinal powder etc. pellet is first made, then pellet is packed into capsule Interior, preparation process is cumbersome, and processing efficiency is low.
Summary of the invention
In view of the above existing problems in the prior art, the present invention provides a kind of production moulds for the double-deck enteric hollow capsule Tool, is directly prepared into the softgel shell with double-layer structure by mold, and medicinal powder can be directly loadable into softgel shell and complete capsule preparation, hence it is evident that Simplify operating procedure, high production efficiency.
To achieve the goals above, a kind of production mould for the double-deck enteric hollow capsule that the present invention uses, the mould Tool is assemblied to form by two identical components one using detachable correspondence, and the component one is by upper mold and lower set of molds At;
The upper mold includes upper cover plate, forming part two and the forming part three that interior softgel shell is cooperatively formed with forming part two, The lower end of forming part three is cylindrical, and bottom end is hemispherical, and the side of forming part three is equipped with closed end, sets in the upper cover plate There are glue pipeline one and glue pipeline two, the glue pipeline one is equipped with the nozzle one that interior softgel shell is formed for injecting glue, glue Liquid pipeline two is equipped with the nozzle two that outer softgel shell is formed for injecting glue, and the side of nozzle two is equipped with upper and lower for being oriented to and limiting The supporting block of mold clamping, the bottom of forming part two are equipped with the support portion for positioning mold molding, are provided with connection in support portion The connecting hole of forming part two and lower mold;
The lower mold includes the forming part one that outer softgel shell can be cooperatively formed with forming part two, the forming part one Inside upper part is equipped with several recessed portions and lug boss assembled convenient for capsule shells connection, and forming part one is led to after upper mold molding It crosses supporting block, closed end and support portion upper mold is fixed in forming part one.
As a further improvement of the present invention, the lower end of forming part one is cylinder, and bottom end is hemispherical.
As a further improvement of the present invention, the support portion is inverted T-shaped, and 6.1 bottom of support portion, two support end is placed In the bottom end of forming part 1.
As a further improvement of the present invention, the forming part one is equipped with pacifies for being oriented to upper mold and forming part one Fixed sharp portion is filled, the section of the sharp portion is triangle, and the supporting block is equipped with the sky cooperated with sharp portion Chamber.
As a preference of the present invention, the mold is assemblied to form by two identical components one using fastening bolt.
As a further improvement of the present invention, the recessed portion and lug boss are respectively ring-type.
Production mould of the invention is assemblied to form using two identical components one, the forming part one in component one and molding Portion two cooperatively forms outer softgel shell, and forming part two and forming part three cooperatively form interior softgel shell, wherein interior softgel shell and outer softgel shell pass through mould Connecting hole in tool forms connection, after mold assembly is good, by the glue pipeline and nozzle injecting glue in upper cover plate, at drying Reason, can be obtained the inside and outside softgel shell being connected and fixed, after mold is dismantled, the double-deck softgel shell of preparation is removed, by inside Medicinal powder is added in softgel shell, then the double-deck enteric hollow capsule is can be obtained into two mutual assembly of bilayer vesicles shell, is prepared with tradition The method of capsulae enterosolubilis is compared, and it is filling again to be not required to for medicinal powder to be processed into pellet using this kind of mold, by inside softgel shell directly Medicinal powder is added, then by two double-deck softgel shell assembly up to required drug, preparation process is simple and convenient, high in machining efficiency.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of component one in the present invention;
Fig. 2 is the structural schematic diagram of upper mold in Fig. 1;
Fig. 3 is the structural schematic diagram of lower mold in Fig. 1;
Fig. 4 is half capsule schematic diagram of inventive die preparation;
In figure: 1, upper cover plate, 2, glue pipeline one, 2.1, nozzle one, 3, glue pipeline two, 3.1, nozzle two, 4, support Block, 5, forming part one, 5.1, recessed portion, 5.2, lug boss, 5.3, sharp portion, 6, forming part two, 6.1, support portion, 6.2, connection Hole, 7, forming part three, 7.1, closed end, 8, interior softgel shell, 9, interconnecting piece, 10, outer softgel shell.
Specific embodiment
The present invention will be further explained below with reference to the attached drawings.
As shown in Figure 1, Figure 2 and Figure 3, a kind of production mould for the double-deck enteric hollow capsule, the mold is by two phases Same component one is assemblied to form using detachable correspondence, and the component one is made of upper mold and lower mold;
The upper mold includes upper cover plate 1, forming part 26 and the forming part that interior softgel shell 8 is cooperatively formed with forming part 26 37, the lower end of forming part 37 is cylindrical, and bottom end is hemispherical, and the side of forming part 37 is equipped with closed end 7.1, described Glue pipeline 1 and glue pipeline 23 are equipped in upper cover plate 1, the glue pipeline 1, which is equipped with, forms capsula interna for injecting glue The nozzle 1 of shell 8, glue pipeline 23, which is equipped with, is used for the nozzle 2 3.1 that injecting glue forms outer softgel shell 10, and the one of nozzle 2 3.1 Side is equipped with the supporting block 4 for being oriented to and limiting upper and lower mold clamping, and the bottom of forming part 26 is equipped with closes for positioning mold The support portion 6.1 of mould is provided with the connecting hole 6.2 of connection forming part 26 and lower mold in support portion 6.1;
The lower mold includes the forming part 1 that outer softgel shell 10 can be cooperatively formed with forming part 26, the forming part One 5 inside upper part is equipped with several recessed portions 5.1 and lug boss 5.2 assembled convenient for capsule shells connection, forming part 1 and upper mold After tool molding, upper mold is fixed in forming part 1 by supporting block 4, closed end 7.1 and support portion 6.1.
As a kind of improvement of embodiment, the lower end of the forming part 1 is cylinder, and bottom end is hemispherical, is passed through Forming part 1 and forming part 26 cooperate, and make the global shape semi-cylindrical of manufactured outer softgel shell 10, and the shape is more suitable Suitable patient, which swallows, to take.
As a kind of improvement of embodiment, the support portion 6.1 is inverted T-shaped, and 6.1 bottom of support portion, two support end is with circle The center in columnar formations portion 1 is symmetrically disposed at the bottom end of forming part 1 as axle center, by support portion 6.1 to forming part 26 Position-limiting action is played, makes that forming part 26 is accurate, is stably mounted in forming part 1, while using inverted T-shaped structure, support effect Fruit is more preferable, and the connecting hole 6.3 in support portion 6.1 can make made of connect between inside and outside softgel shell in bilayer softgel shell it is more steady It is fixed, firm.
As a kind of improvement of embodiment, the forming part 1 is equipped with pacifies for being oriented to upper mold and forming part 1 Fixed sharp portion 5.3 is filled, the section of the sharp portion 5.3 is triangle, and the supporting block 4 is equipped with and sharp portion The cavitys of 5.3 cooperations, by mutually matched sharp portion 5.3 and cavity, make upper mold faster, more quasi- be mounted on forming part one On 5, while by the guiding and position-limiting action of supporting block 4, enable the accurate injecting glue of nozzle 2 3.1 on glue pipeline 23, it is ensured that The preparation efficiency of outer softgel shell 10.
As the preferred of embodiment, which is assemblied to form by two identical components one using fastening bolt, passes through spiral shell Bolt assembles to obtain mold of the invention, after the processing such as injecting glue, drying, two disassembling bolts, separation components one is obtained double Layer softgel shell, easy to operate, easy to use, the double-deck softgel shell effect of installation effectiveness height and preparation is good.
As a kind of improvement of embodiment, as shown in figure 4, the recessed portion 5.1 and lug boss 5.2 are respectively ring-type, The interconnecting piece 9 on outer softgel shell 10 is formed by several recessed portions 5.1 and lug boss 5.2, convenient for being assembled in two double-deck softgel shells Together, and cricoid structure, keep the connection between outer softgel shell 10 more firm.
It is bolted together in use, two identical components one are corresponded to get to mold of the invention, passes through upper mold In glue pipeline 23 and glue pipeline 1 be injected separately into the outer softgel shell 10 of preparation and interior softgel shell 8 needed for glue, knot to be injected Shu Hou, drying, mold is dismantled, separates two components one, and at this time up to the double-deck softgel shell, inside softgel shell 9 is interior to be added medicinal powder, then It takes the double-deck softgel shell of other sky to be sleeved on the double-deck softgel shell containing medicinal powder as capsule cap, passes through the interconnecting piece on outer softgel shell 10 9 are connected and fixed the two, the double-deck enteric hollow capsule of needs are finally obtained, in order to keep the double-deck softgel shell as capsule cap more preferable Be sleeved on the double-deck capsule of powder charge powder, can be identical using structure, but the mold that size is bigger, the bilayer prepared at this time is empty Capsule shells size is slightly larger, can preferably be sleeved in the capsule shells for containing medicinal powder as capsule cap.The mold is easy to use, letter Change traditional preparation section, effectively increases production efficiency.

Claims (1)

1. a kind of production mould for the double-deck enteric hollow capsule, which is characterized in that the mold is by two identical components one It is assemblied to form using fastening bolt, the component one is made of upper mold and lower mold;
The upper mold include upper cover plate (1), forming part two (6) and with forming part two (6) cooperatively form interior softgel shell (8) at The lower end in type portion three (7), forming part three (7) is cylindrical, and bottom end is hemispherical, and the side of forming part three (7) is equipped with closed end (7.1), glue pipeline one (2) and glue pipeline two (3) are equipped in the upper cover plate (1), on the glue pipeline one (2) Equipped with the nozzle one (2.1) for forming interior softgel shell (8) for injecting glue, glue pipeline two (3), which is equipped with, forms outer softgel shell for injecting glue (10) nozzle two (3.1), the side of nozzle two (3.1) are equipped with the supporting block for being oriented to and limiting upper and lower mold clamping (4), the bottom of forming part two (6) is equipped with the support portion (6.1) for positioning mold molding, is provided with connection in support portion (6.1) The connecting hole (6.2) of forming part two (6) and lower mold;
The lower mold includes the forming part one (5) that outer softgel shell (10) can be cooperatively formed with forming part two (6), the molding The inside upper part in portion one (5) is equipped with several recessed portions (5.1) and lug boss (5.2) assembled convenient for capsule shells connection, described Recessed portion (5.1) and lug boss (5.2) are respectively ring-type, after forming part one (5) and upper mold mold, pass through supporting block (4), envelope Upper mold is fixed in forming part one (5) by closed end (7.1) and support portion (6.1);
The lower end of the forming part one (5) is cylinder, and bottom end is hemispherical;The support portion (6.1) is inverted T-shaped, branch Two support end of support part (6.1) bottom is placed on the bottom end of forming part one (5);The forming part one (5) is equipped with for being oriented to The sharp portion (5.3) of upper mold and forming part one (5) installation fixation, the section of the sharp portion (5.3) is triangle, described Supporting block (4) be equipped with the cavity that cooperates with sharp portion (5.3).
CN201510270072.2A 2015-05-23 2015-05-23 Production mould for the double-deck enteric hollow capsule Expired - Fee Related CN104905967B (en)

Priority Applications (1)

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Application Number Priority Date Filing Date Title
CN201510270072.2A CN104905967B (en) 2015-05-23 2015-05-23 Production mould for the double-deck enteric hollow capsule

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CN104905967B true CN104905967B (en) 2019-04-16

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107550737B (en) * 2017-08-25 2020-05-05 贵州盛茂白芨开发有限公司 Method for preparing bletilla striata polysaccharide capsule
CN108264410A (en) * 2018-03-01 2018-07-10 闫超 A kind of bilayered microcapsule coating of fertilizer

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1455884A (en) * 1973-02-14 1976-11-17 Lilly Industries Ltd Production of capsules
CN201750916U (en) * 2010-06-07 2011-02-23 湖北中烟工业有限责任公司 Three-layer soft capsule dropper head device
CN102552209A (en) * 2012-01-06 2012-07-11 安徽黄山胶囊股份有限公司 Double-layer hollow capsule and multi-layer enteric hollow capsule
CN103786326A (en) * 2014-01-10 2014-05-14 芜湖新磊塑胶科技有限公司 Mold for manufacturing double-layer pipe fitting and manufacturing method of double-layer pipe fitting
CN204106589U (en) * 2014-07-28 2015-01-21 绍兴中亚胶囊有限公司 A kind of multi-functional hollow capsule mold

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4472035B2 (en) * 1998-06-17 2010-06-02 森下仁丹株式会社 Capsule formulation with excellent long-term storage stability

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1455884A (en) * 1973-02-14 1976-11-17 Lilly Industries Ltd Production of capsules
CN201750916U (en) * 2010-06-07 2011-02-23 湖北中烟工业有限责任公司 Three-layer soft capsule dropper head device
CN102552209A (en) * 2012-01-06 2012-07-11 安徽黄山胶囊股份有限公司 Double-layer hollow capsule and multi-layer enteric hollow capsule
CN103786326A (en) * 2014-01-10 2014-05-14 芜湖新磊塑胶科技有限公司 Mold for manufacturing double-layer pipe fitting and manufacturing method of double-layer pipe fitting
CN204106589U (en) * 2014-07-28 2015-01-21 绍兴中亚胶囊有限公司 A kind of multi-functional hollow capsule mold

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Termination date: 20210523