CN104889103A - Cleaning technology of powder-injection reagent bottle for injection - Google Patents

Cleaning technology of powder-injection reagent bottle for injection Download PDF

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Publication number
CN104889103A
CN104889103A CN201510235006.1A CN201510235006A CN104889103A CN 104889103 A CN104889103 A CN 104889103A CN 201510235006 A CN201510235006 A CN 201510235006A CN 104889103 A CN104889103 A CN 104889103A
Authority
CN
China
Prior art keywords
reagent bottle
injection
cleaning
cylindrical shell
cover
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510235006.1A
Other languages
Chinese (zh)
Inventor
廖成斌
卢朝成
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chengdu Zhongmu Biological Pharmaceutical Co Ltd
Original Assignee
Chengdu Zhongmu Biological Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chengdu Zhongmu Biological Pharmaceutical Co Ltd filed Critical Chengdu Zhongmu Biological Pharmaceutical Co Ltd
Priority to CN201510235006.1A priority Critical patent/CN104889103A/en
Publication of CN104889103A publication Critical patent/CN104889103A/en
Pending legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B3/00Cleaning by methods involving the use or presence of liquid or steam
    • B08B3/04Cleaning involving contact with liquid
    • B08B3/10Cleaning involving contact with liquid with additional treatment of the liquid or of the object being cleaned, e.g. by heat, by electricity or by vibration
    • B08B3/12Cleaning involving contact with liquid with additional treatment of the liquid or of the object being cleaned, e.g. by heat, by electricity or by vibration by sonic or ultrasonic vibrations
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B13/00Accessories or details of general applicability for machines or apparatus for cleaning
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B3/00Cleaning by methods involving the use or presence of liquid or steam
    • B08B3/04Cleaning involving contact with liquid
    • B08B3/08Cleaning involving contact with liquid the liquid having chemical or dissolving effect
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B2203/00Details of cleaning machines or methods involving the use or presence of liquid or steam
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B2203/00Details of cleaning machines or methods involving the use or presence of liquid or steam
    • B08B2203/02Details of machines or methods for cleaning by the force of jets or sprays
    • B08B2203/0288Ultra or megasonic jets

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cleaning In General (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

The invention relates to a cleaning technology of a powder-injection reagent bottle for injection. The technology comprises the following steps that firstly, the reagent bottle required to be cleaned is soaked in a hydrochloric acid solution with the concentration ranging from 0.01 mol/L to 0.1 mol/L; secondly, the soaked reagent bottle is placed in ultrasonic equipment to be washed in an ultrasonic oscillation manner, and after ultrasonic treatment is carried out, water on the inner wall and the outer wall of the reagent bottle is drained off; thirdly, after the reagent bottle is drained off, the bottle is repeatedly washed with water in a spraying manner, and then is dried through air, and after air drying, the bottle is dried through an oven; and finally, a moist heat sterilization method is adopted for conducting sterilization. The problem of the low reagent bottle cleaning speed caused by an existing cleaning technology of the powder-injection reagent bottle for injection is solved.

Description

The cleaning of powder ampoule agent for injection reagent bottle
Technical field
The present invention relates to the cleaning method field of reagent bottle, particularly, relate to a kind of cleaning of powder ampoule agent for injection reagent bottle.
Background technology
powder-injection is after being mixed with reagent by medicine, the granular goods formed after sterilization and drying, is convenient to transport and preserves.Powder-injection carries out dilution injection when applying with glucose solution, and injection can dilute can directly inject according to consumption difference.Powder pin, as a kind of common formulation, can be divided into aseptic powder and freeze-dried powder according to preparation principle, both have any different in shape, and aseptic subpackaged is Powdered, and freeze-dried powder is block, and both all require to prepare in sterile workshop.
The effect and the security that how to improve injecting drug use always are that pharmaceutical producing enterprise wishes the problem solved, the effect of injecting drug use solves from two aspects with safety is main, one is effect and the safety that Formulation guarantees medication, and two is effect and the safety that the process for producing of medicine guarantees medicine.Ceftriaxone for inj is a most existing injection agent, and its prescription is single, guarantees that the effect of its medicine and safe main path are exactly by controlling its preparation technology.
The cleaning of existing powder ampoule agent for injection reagent bottle causes the speed of cleaning reagent bottle slower.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of cleaning of powder ampoule agent for injection reagent bottle, to overcome the slow problem that existing powder ampoule agent for injection reagent bottle causes cleaning cleaning reagent bottle.
The present invention's adopted technical scheme that solves the problem is: the cleaning of powder ampoule agent for injection reagent bottle, comprises the following steps:
First, the reagent bottle of needs cleaning being soaked in concentration is in the hydrochloric acid solution of 0.01mol/L-0.1 mol/L;
Secondly, the reagent bottle after soaking is placed in ultrasonic device carry out ultrasonic vibration washing, ultrasonic after the water of reagent bottle inside and outside wall is drained;
Then, reagent bottle repeatedly carries out fountain flushing with water after draining, then with air oven dry, uses oven for drying again after air oven dry;
Finally, moist hear heat test is adopted to carry out sterilizing, the cover that the bactericidal unit that described moist heat sterilization adopts comprises cylindrical shell, coordinates with cylindrical shell, cylindrical shell is provided with shift knob, jack, cover is provided with air nozzle, Pressure gauge, the outer wall that cylindrical shell coordinates with cover is provided with annular nib, and the outer wall of annular nib, cover is provided with the fixed block that at least 4 groups cooperatively interact, fixed block inside is provided with tapped through hole, and the leading screw being equipped with nut is located in tapped through hole.The cleaning of existing powder ampoule agent for injection reagent bottle be all generally comprise ultrasonic, washing, dry, the steps such as sterilizing, the efficiency of washing is slower, the speed of cleaning reagent bottle is slower, the present invention by first cleaning with certain density hydrochloric acid solution before carrying out ultrasonic vibration to reagent bottle, hydrochloric acid solution can dirt fast on solubilising reagent bottle, the tough stains made comes off, carry out ultrasonic, now ultrasonicly just can fast dirt to be shaken off, improve dirt comes off in the speed of reagent bottle, so, the cleaning cleaning reagent bottle that instant invention overcomes existing powder ampoule agent for injection reagent bottle causes slow problem.
Further, the concentration of hydrochloric acid solution is 0.05mol/L.
Further, cover upper surface is provided with hand-held rod.The open and close of cover are convenient in the setting of hand-held rod, improve the convenience of operation.
Further, the lower end sidewall of cylindrical shell is provided with outlet pipe.The setting of outlet pipe is convenient to sterilization water directly be discharged from outlet pipe after sterilizing terminates, and improves the convenience of operation.
To sum up, the invention has the beneficial effects as follows:
1, the present invention by first cleaning with certain density hydrochloric acid solution before carrying out ultrasonic vibration to reagent bottle, hydrochloric acid solution can dirt fast on solubilising reagent bottle, the tough stains made comes off, carry out ultrasonic, now ultrasonicly just fast dirt can be shaken off, to improve dirt and come off in the speed of reagent bottle.
2, the present invention is provided with outlet pipe by the lower end sidewall that is provided with hand-held rod, cylindrical shell in cover upper surface; Improve the convenience of operation.
Accompanying drawing explanation
Fig. 1 is the structural representation of bactericidal unit.
Mark and corresponding parts title in accompanying drawing:
1-cylindrical shell; 2-cover; 3-air nozzle; 4-hand-held rod; 5-Pressure gauge; 6-leading screw; 11-annular nib; 12-fixed block; 13-jack; 14-shift knob; 15-outlet pipe.
Detailed description of the invention
Below in conjunction with embodiment and accompanying drawing, to the detailed description further of invention do, but embodiments of the present invention are not limited thereto.
Embodiment:
As shown in Figure 1, the cleaning of powder ampoule agent for injection reagent bottle, comprises the following steps:
First, the reagent bottle of needs cleaning being soaked in concentration is in the hydrochloric acid solution of 0.05mol/L;
Secondly, the reagent bottle after soaking is placed in ultrasonic device carry out ultrasonic vibration washing, ultrasonic after the water of reagent bottle inside and outside wall is drained;
Then, reagent bottle repeatedly carries out fountain flushing with water after draining, then with air oven dry, uses oven for drying again after air oven dry;
Finally, moist hear heat test is adopted to carry out sterilizing, the cover 2 that the bactericidal unit that described moist heat sterilization adopts comprises cylindrical shell 1, coordinates with cylindrical shell 1, cylindrical shell 1 is provided with shift knob 14, jack 13, outlet pipe 15, cover 2 is provided with air nozzle 3, Pressure gauge 5, hand-held rod 4, the outer wall that cylindrical shell 1 coordinates with cover 2 is provided with annular nib 11, the outer wall of annular nib 11, cover 2 is provided with 8 groups of fixed blocks cooperatively interacted 12, fixed block 12 inside is provided with tapped through hole, and the leading screw 6 being equipped with nut is located in tapped through hole.
As mentioned above, the present invention can be realized preferably.

Claims (4)

1. the cleaning of powder ampoule agent for injection reagent bottle, is characterized in that, comprises the following steps:
First, the reagent bottle of needs cleaning being soaked in concentration is in the hydrochloric acid solution of 0.01mol/L-0.1 mol/L;
Secondly, the reagent bottle after soaking is placed in ultrasonic device carry out ultrasonic vibration washing, ultrasonic after the water of reagent bottle inside and outside wall is drained;
Then, reagent bottle repeatedly carries out fountain flushing with water after draining, then with air oven dry, uses oven for drying again after air oven dry;
Finally, moist hear heat test is adopted to carry out sterilizing, the bactericidal unit that described moist heat sterilization adopts comprises cylindrical shell (1), the cover (2) coordinated with cylindrical shell (1), cylindrical shell (1) is provided with shift knob (14), jack (13), cover (2) is provided with air nozzle (3), Pressure gauge (5), the outer wall that cylindrical shell (1) coordinates with cover (2) is provided with annular nib (11), annular nib (11), the outer wall of cover (2) is provided with the fixed block (12) that at least 4 groups cooperatively interact, fixed block (12) inside is provided with tapped through hole, the leading screw (6) being equipped with nut is located in tapped through hole.
2. the cleaning of powder ampoule agent for injection reagent bottle according to claim 1, is characterized in that, the concentration of described hydrochloric acid solution is 0.05mol/L.
3. the cleaning of powder ampoule agent for injection reagent bottle according to claim 1, is characterized in that, described cover (2) upper surface is provided with hand-held rod (4).
4., according to the cleaning of the arbitrary described powder ampoule agent for injection reagent bottle of claims 1 to 3, it is characterized in that, the lower end sidewall of described cylindrical shell (1) is provided with outlet pipe (15).
CN201510235006.1A 2015-05-11 2015-05-11 Cleaning technology of powder-injection reagent bottle for injection Pending CN104889103A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510235006.1A CN104889103A (en) 2015-05-11 2015-05-11 Cleaning technology of powder-injection reagent bottle for injection

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510235006.1A CN104889103A (en) 2015-05-11 2015-05-11 Cleaning technology of powder-injection reagent bottle for injection

Publications (1)

Publication Number Publication Date
CN104889103A true CN104889103A (en) 2015-09-09

Family

ID=54022299

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510235006.1A Pending CN104889103A (en) 2015-05-11 2015-05-11 Cleaning technology of powder-injection reagent bottle for injection

Country Status (1)

Country Link
CN (1) CN104889103A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105149307A (en) * 2015-10-20 2015-12-16 泉州市尊生酒业有限公司 Winebottle cleaning device

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04207030A (en) * 1990-11-30 1992-07-29 Fujitsu Ltd Method and apparatus for ultrasonic cleaning
CN2497892Y (en) * 2001-08-25 2002-07-03 湖南省郴州市山河电子设备有限公司 Ultrasonic bottle washer
CN202554530U (en) * 2012-05-19 2012-11-28 成都中牧生物药业有限公司 Soak disinfection pool for cleaning medicine bottles
CN102895181A (en) * 2012-10-22 2013-01-30 四川制药制剂有限公司 Method for preparing mezlocillin sodium for injection
CN203400336U (en) * 2013-07-08 2014-01-22 桐乡恒基生物有限公司 Sterilization device
CN104307790A (en) * 2014-10-11 2015-01-28 赵济彦 Medical device cleaning and sterilizing device

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04207030A (en) * 1990-11-30 1992-07-29 Fujitsu Ltd Method and apparatus for ultrasonic cleaning
CN2497892Y (en) * 2001-08-25 2002-07-03 湖南省郴州市山河电子设备有限公司 Ultrasonic bottle washer
CN202554530U (en) * 2012-05-19 2012-11-28 成都中牧生物药业有限公司 Soak disinfection pool for cleaning medicine bottles
CN102895181A (en) * 2012-10-22 2013-01-30 四川制药制剂有限公司 Method for preparing mezlocillin sodium for injection
CN203400336U (en) * 2013-07-08 2014-01-22 桐乡恒基生物有限公司 Sterilization device
CN104307790A (en) * 2014-10-11 2015-01-28 赵济彦 Medical device cleaning and sterilizing device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105149307A (en) * 2015-10-20 2015-12-16 泉州市尊生酒业有限公司 Winebottle cleaning device

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Application publication date: 20150909

RJ01 Rejection of invention patent application after publication