CN104857324A - Traditional Chinese medicine composition for treating migraine - Google Patents
Traditional Chinese medicine composition for treating migraine Download PDFInfo
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- CN104857324A CN104857324A CN201510302653.XA CN201510302653A CN104857324A CN 104857324 A CN104857324 A CN 104857324A CN 201510302653 A CN201510302653 A CN 201510302653A CN 104857324 A CN104857324 A CN 104857324A
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Abstract
The invention relates to a traditional Chinese medicine composition for treating migraine, and belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicines by weight: 10-15 g of poria, 20-30 g of rhizoma gastrodiae, 20-30 g of ramulus uncariae cum uncis, 12-15 g of radix astragali, 12-15 g of radix achyranthis, 10-15 g of radix bupleuri, 6-10 g of radix saposhnikoviae, 6-10 g of radix notoginseng, 10-15 g of herba erodii, 12-15 g of radix angelicae sinensis, 6-10 g of radix polygoni multiflori, 10-15 g of semen persicae, 8-10 g of fructus citri sarcodactylis, 10-15 g of rhizoma anemarrhenae, 8-10 g of lignum dalbergiae odoriferae, 20-25 g of radix paeoniae alba, 8-10 g of radix adenophorae and 6-10 g of semen litchi.
Description
Technical field
The present invention relates to one and treat migrainous Chinese medicine composition, belong to technical field of Chinese medicines.
Background technology
Migraine is a kind of chronic disease that slight or severe is had a headache that occurs repeatedly, usually with various autonomic nervous system symptom.Usual this headache is one-sided character (only relating to side head), and with beating, sustainable 2-72 hour.Related symptoms may comprise Nausea and vomiting, probably light (more responsive to light), probably sound (more responsive to sound), and the sensation that limb activity can aggravate the pain.The migraineur of 1/3rd all can feel disease tendency: of short duration vision, sensation, language or physical handicaps all mean that headache is about to outbreak.
The migrainous cause of disease is considered to caused by the comprehensive function of environmental factors and inherited genetic factors.The case of about 2/3rds has the reason of inherited genetic factors.The fluctuation of hormone level also may be a factor: before adolescence, and the boy being subject to migraine impact is slightly more than young girl, but after this, the women being subject to migraine impact then will have more two to three times than male.Usually at phenolics, migrainous impact can weaken.Migrainous accurate pathogenesis is still unknown at present.But people generally believe this is because neural blood vessel disorder causes.Pathology main is at present interpreted as corticocerebral excitement levels to be strengthened, and the neuronic pain in brain stem in nuclei quintus controls abnormal.
Recommend initial therapy can use simple analgesic, as ibuprofen and acetaminophen treat headache, and use antiemetic nauseating to treat, anti-anti-nausea.Medicaments, as Qu Putan class or Ergotamine then can be selected when simple analgesic effect is not good.These Western medicine all have certain side effect, and these medicines have certain curative effect in a short time, but will effect a radical cure migraine Western medicine for a long time and then seem unable to do what one wishes.
Summary of the invention
In order to overcome prior art Chinese medicine and western medicine, the deficiency thought of and there is side effect being paid no attention to treatment migraine, the invention provides the migrainous Chinese medicine composition of a kind for the treatment of evident in efficacy, that have no side effect.
For achieving the above object, the technical scheme that the present invention takes is, treating migrainous Chinese medicine composition, is be made up of the Chinese medicine of following weight: Poria 10-15g, Rhizoma Gastrodiae 20-30g, Ramulus Uncariae Cum Uncis 20-30g, the Radix Astragali 12-15g, Radix Achyranthis Bidentatae 12-15g, Radix Bupleuri 10-15g, Radix Saposhnikoviae 6-10g, Radix Notoginseng 6-10g, geranium 10-15g, Radix Angelicae Sinensis 12-15g, Radix Polygoni Multiflori 6-10g, Semen Persicae 10-15g, Fructus Citri Sarcodactylis 8-10g, the Rhizoma Anemarrhenae 10-15g, Lignum Dalbergiae Odoriferae 8-10g, the Radix Paeoniae Alba 20-25g, Radix Adenophorae 8-10g, Semen Litchi 6-10g.
Be preferably, treating migrainous Chinese medicine composition, is be made up of the Chinese medicine of following weight: Poria 12g, Rhizoma Gastrodiae 25g, Ramulus Uncariae Cum Uncis 28g, Radix Astragali 12g, Radix Achyranthis Bidentatae 14g, Radix Bupleuri 12g, Radix Saposhnikoviae 8g, Radix Notoginseng 8g, geranium 12g, Radix Angelicae Sinensis 14g, Radix Polygoni Multiflori 8g, Semen Persicae 12g, Fructus Citri Sarcodactylis 8g, Rhizoma Anemarrhenae 12g, Lignum Dalbergiae Odoriferae 9g, Radix Paeoniae Alba 22g, Radix Adenophorae 8g, Semen Litchi 8g.
Poria: sweet in the mouth, light; Property is put down; GUIXIN, lung, spleen, kidney channel; There is promoting diuresis to eliminate damp pathogen, spleen invigorating and in, effect of mind tranquilizing and the heart calming.
Rhizoma Gastrodiae: sweet in the mouth, property is put down; Return Liver Channel; There is breath west wind suppressing the hyperactive liver, suppressing liver-YANG, effect of wind dispelling dredging collateral.
Ramulus Uncariae Cum Uncis: sweet in the mouth, cool in nature; Return liver, pericardium channel; There is the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., effect of heat clearing away suppressing the hyperactive liver.
The Radix Astragali: sweet in the mouth; Warm in nature; Return lung, spleen channel; There is benefit strengthening spleen and lung, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, effect of poison holding sore.
Radix Achyranthis Bidentatae: bitter in the mouth, acid; Property is put down; Return liver, kidney channel; There is the kidney invigorating liver, ask muscles and bones, promoting blood circulation to restore menstrual flow, conducting blood to flow downwards, effect of inducing diuresis for treating stranguria syndrome.
Radix Bupleuri: bitter in the mouth, cold nature; Return liver, gallbladder meridian; There is reconciling superficies and interior, dispersing the stagnated live-QI to relieve the stagnation of QI, effect of elevate a turnable ladder yang-energy.
Radix Saposhnikoviae: acrid in the mouth, sweet; Slightly warm in nature; Return bladder, lung, spleen channel; Having dispels the wind delivers, removing dampness to relieve pain, effect of relieving convulsion.
Radix Notoginseng: sweet in the mouth, bitter in the mouth; Warm in nature; Return liver, stomach warp; There is dissipating blood stasis hemostasis, effect of subduing swelling and relieving pain.
Geranium: bitter in the mouth, pungent; Property is put down; Return liver,spleen,kidney warp; There is expelling wind and removing dampness, the meridian dredging, antidiarrheal dysentery, effect of promoting blood circulation and detumescence.
Radix Angelicae Sinensis: sweet in the mouth, pungent, bitter, warm in nature, GUIXIN, liver, spleen channel; Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, effect of profit soup relieving constipation.
Radix Polygoni Multiflori Preparata: sweet in the mouth, puckery; Slightly warm in nature; Return liver, kidney channel; There is enrich and benefit essence and blood, the effect of the crow palpus that reinforces the kidney.
Semen Persicae: bitter in the mouth, sweet; Property is put down; Slightly poisonous; GUIXIN, liver, large intestine channel; There is blood circulation promoting and blood stasis dispelling, effect of loosening bowel to relieve constipation.
Fructus Citri Sarcodactylis: bitter in the mouth, pungent, sour; Warm in nature; Return liver, stomach, lung meridian; There is soothing the liver circulation of qi promoting, and stomach and alleviating pain, effect of drying dampness to eliminate phlegm.
The Rhizoma Anemarrhenae: bitter in the mouth, sweet, cold in nature; Return lung, stomach, kidney channel; There is clearing away heat-fire, nourshing Yin and drynsessmoistening prescription, the effect of relieving restlessness of quenching the thirst.
Lignum Dalbergiae Odoriferae: acrid in the mouth, warm in nature; Return liver, spleen, heart channel; There is promoting flow of QI and blood, effect of pain relieving, hemostasis.
The Radix Paeoniae Alba: bitter in the mouth, acid; Cold nature; Return liver, spleen channel; Have and nourish blood and seek, easing the affected liver to relieve pain, effect of suppressing liver-YANG.
Radix Adenophorae: sweet in the mouth; Cold nature; Attach to the lung and stomach meridians; There is replenishing YIN and removing heat, moistening the lung and resolving phlegm, effect of reinforcing stomach reg fluid.
Semen Litchi: sweet in the mouth, micro-hardship; Warm in nature; Return liver, kidney, stomach warp; There is promoting QI to circulate and dispersing the agglomeration of the pathogens, effect of cold-dispelling pain-relieving.
Preparation method
Above-mentioned Chinese medicine preparation method is traditionally made decoction, and every day is sooner or later each once oral.
The animal toxicity test of medicine of the present invention
Get rabbit 60, male and female dual-purpose, body weight 2.0-3.0kg, be divided into two groups, one group is overdose experimental group, and another group is normal amount experimental group.Overdose group is 30ml ∕ kg, and normal amount group is 10 ml ∕ kg, and administering mode is administration by gavage administration, and every day respectively once, takes 30 days sooner or later continuously, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
One provided by the invention treats migrainous Chinese medicine composition, with nourshing blood and promoting blood circulation, heat clearing away is soothing the liver, eliminating blood stasis and smoothing collaterals, spasmolytic pain relieving is for Therapeutic Principle, various material medicines in component are coordinated together mutually, can play and farthest play drug effect, effectively can regulate equilibrium between yin and yang and the self-coordination ability of patient's body, there is good absorbing effect, evident in efficacy, have no side effect, the advantage that safety is high.
Below in conjunction with clinical data and model case, beneficial effect of the present invention is further illustrated.
One, clinical data
One provided by the invention is adopted to treat migrainous Chinese medicine composition from January, 2013--in January, 2015 treats migraineur 136 people, wherein male 57 people, women 79 people, age 16--65 year, the shortest person of the course of disease 6 months, most elder 8 years, average 3 years.
Two, Therapeutic Method
Adopt the decoction prepared by Chinese medicine composition of the present invention, every day is sooner or later each once oral, within 5 days, is a course for the treatment of.
Three, efficacy assessment standard
Recovery from illness: migraine Clinical symptom and sign disappears completely, without recurrence in 1 year.
Effective: migraine clinical symptoms substantially disappears or obviously alleviates.
Effective: migraine clinical symptoms makes moderate progress, and attack times reduces to some extent.
Invalid: migraine clinical symptoms is without change.
Four, therapeutic outcome
The present invention treats migraineur 136 example, and through the treatment of 2-5 courses for the treatment of, recovery from illness 130 example, accounts for 95.5%, and effective 3 examples, account for 2.2%, invalid 3 examples, and account for 2.2%, total effective rate is 97.7%, has no any side effect; Cure in 130 examples, 2 courses for the treatment of cure 28 examples, and 3 courses for the treatment of cure 46 examples, and 4 courses for the treatment of cure 44 examples, and 5 courses for the treatment of cure 12 examples; Result shows, the present invention has good effect, and instant effect has no side effect, the advantage not easily recurred more.
Five, model case
Case 1
Liu, female, 54 years old, top managers, migraine 6 years has been suffered from patient's private prosecution, severe headache during outbreak, outbreak in week 1-3 time, each outbreak continues 2-6 hours, simultaneously with nausea and vomiting, photophobia, easily has a sleepless night, and once takes somedon etc. and to relieve the pain class Western medicine, can temporary relief of symptoms after taking medicine.Take 1 course for the treatment of of Chinese medicine composition of the present invention, symptom is clearly better, and continues again to take 3 courses for the treatment of, and cephalagra disappears completely, follows up a case by regular visits to and does not recur for 1 year.
Case 2
Zhang, man, 26 years old, student, patient's private prosecution suffers from migraine 1 year, heavy time light during outbreak, outbreak in a week 1-2 times, 1-2 hours persistent period, during insomnia, second day severe headache, simultaneously with nausea and vomiting, photophobia.Take 1 course for the treatment of of Chinese medicine composition of the present invention, cephalagra is clearly better, and take again 2 courses for the treatment of continuously, cephalagra disappears completely.
Case 3
Huang, female, 36 years old, migraine 6 months on the right side of paroxysmal, often vexed, dreaminess, lumbago, outbreak in a week 1-2 times, 1-3 hours persistent period.Take this present invention Chinese medicine composition 3 days, symptom is clearly better, and continue again to take 10 days, symptom disappears completely, follows up a case by regular visits to and has no recurrence half a year.
Detailed description of the invention
Embodiment 1
Treating migrainous Chinese medicine composition, is be made up of the Chinese medicine of following weight: Poria 12g, Rhizoma Gastrodiae 25g, Ramulus Uncariae Cum Uncis 28g, Radix Astragali 12g, Radix Achyranthis Bidentatae 14g, Radix Bupleuri 12g, Radix Saposhnikoviae 8g, Radix Notoginseng 8g, geranium 12g, Radix Angelicae Sinensis 14g, Radix Polygoni Multiflori 8g, Semen Persicae 12g, Fructus Citri Sarcodactylis 8g, Rhizoma Anemarrhenae 12g, Lignum Dalbergiae Odoriferae 9g, Radix Paeoniae Alba 22g, Radix Adenophorae 8g, Semen Litchi 8g.Above-mentioned Chinese medicine preparation method is traditionally made decoction, and every day is sooner or later each once oral.
Embodiment 2
Treating migrainous Chinese medicine composition, is be made up of the Chinese medicine of following weight: Poria 10g, Rhizoma Gastrodiae 28g, Ramulus Uncariae Cum Uncis 28g, Radix Astragali 12g, Radix Achyranthis Bidentatae 12g, Radix Bupleuri 14g, Radix Saposhnikoviae 6g, Radix Notoginseng 8g, geranium 12g, Radix Angelicae Sinensis 13g, Radix Polygoni Multiflori 8g, Semen Persicae 10g, Fructus Citri Sarcodactylis 9g, Rhizoma Anemarrhenae 13g, Lignum Dalbergiae Odoriferae 8g, Radix Paeoniae Alba 23g, Radix Adenophorae 8g, Semen Litchi 8g.Above-mentioned Chinese medicine preparation method is traditionally made decoction, and every day is sooner or later each once oral.
Embodiment 3
Treating migrainous Chinese medicine composition, is be made up of the Chinese medicine of following weight: Poria 14g, Rhizoma Gastrodiae 26g, Ramulus Uncariae Cum Uncis 30g, Radix Astragali 13g, Radix Achyranthis Bidentatae 13g, Radix Bupleuri 12g, Radix Saposhnikoviae 10g, Radix Notoginseng 8g, geranium 14g, Radix Angelicae Sinensis 12g, Radix Polygoni Multiflori 8g, Semen Persicae 14g, Fructus Citri Sarcodactylis 8g, Rhizoma Anemarrhenae 13g, Lignum Dalbergiae Odoriferae 9g, Radix Paeoniae Alba 22g, Radix Adenophorae 9g, Semen Litchi 9g.Above-mentioned Chinese medicine preparation method is traditionally made decoction, and every day is sooner or later each once oral.
Claims (2)
1. treat migrainous Chinese medicine composition, it is characterized in that: be made up of the Chinese medicine of following weight: Poria 10-15g, Rhizoma Gastrodiae 20-30g, Ramulus Uncariae Cum Uncis 20-30g, the Radix Astragali 12-15g, Radix Achyranthis Bidentatae 12-15g, Radix Bupleuri 10-15g, Radix Saposhnikoviae 6-10g, Radix Notoginseng 6-10g, geranium 10-15g, Radix Angelicae Sinensis 12-15g, Radix Polygoni Multiflori 6-10g, Semen Persicae 10-15g, Fructus Citri Sarcodactylis 8-10g, the Rhizoma Anemarrhenae 10-15g, Lignum Dalbergiae Odoriferae 8-10g, the Radix Paeoniae Alba 20-25g, Radix Adenophorae 8-10g, Semen Litchi 6-10g.
2. the migrainous Chinese medicine composition for the treatment of according to claim 1, is characterized in that: be made up of the Chinese medicine of following weight: Poria 12g, Rhizoma Gastrodiae 25g, Ramulus Uncariae Cum Uncis 28g, Radix Astragali 12g, Radix Achyranthis Bidentatae 14g, Radix Bupleuri 12g, Radix Saposhnikoviae 8g, Radix Notoginseng 8g, geranium 12g, Radix Angelicae Sinensis 14g, Radix Polygoni Multiflori 8g, Semen Persicae 12g, Fructus Citri Sarcodactylis 8g, Rhizoma Anemarrhenae 12g, Lignum Dalbergiae Odoriferae 9g, Radix Paeoniae Alba 22g, Radix Adenophorae 8g, Semen Litchi 8g.
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| CN201510302653.XA CN104857324A (en) | 2015-06-05 | 2015-06-05 | Traditional Chinese medicine composition for treating migraine |
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| CN201510302653.XA CN104857324A (en) | 2015-06-05 | 2015-06-05 | Traditional Chinese medicine composition for treating migraine |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006002096A2 (en) * | 2004-06-18 | 2006-01-05 | Vivo Therapeutics, Inc. | Low doses of l-citrulline for treating diseases |
| CN103610945A (en) * | 2013-12-02 | 2014-03-05 | 王凤芹 | Traditional Chinese medicine composition for treating migraine |
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2015
- 2015-06-05 CN CN201510302653.XA patent/CN104857324A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006002096A2 (en) * | 2004-06-18 | 2006-01-05 | Vivo Therapeutics, Inc. | Low doses of l-citrulline for treating diseases |
| CN103610945A (en) * | 2013-12-02 | 2014-03-05 | 王凤芹 | Traditional Chinese medicine composition for treating migraine |
Non-Patent Citations (1)
| Title |
|---|
| 杨立波: "天麻钩藤饮加减治疗偏头痛68例", 《江西中医药》 * |
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Application publication date: 20150826 |
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