CN104849130B - Evenly mixing device and mixing method - Google Patents

Evenly mixing device and mixing method Download PDF

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Publication number
CN104849130B
CN104849130B CN201510305491.5A CN201510305491A CN104849130B CN 104849130 B CN104849130 B CN 104849130B CN 201510305491 A CN201510305491 A CN 201510305491A CN 104849130 B CN104849130 B CN 104849130B
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China
Prior art keywords
reagent
tubular container
plectrum
kit
agent bin
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CN201510305491.5A
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Chinese (zh)
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CN104849130A (en
Inventor
柳建敏
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Ningbo sea one biological technology Co., Ltd.
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Ningbo Sea One Biological Technology Co Ltd
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Priority to CN201510305491.5A priority Critical patent/CN104849130B/en
Publication of CN104849130A publication Critical patent/CN104849130A/en
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  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The invention discloses a kind of evenly mixing devices comprising agent bin, the reagent disc being movably arranged in agent bin, the driving device of driving institute reagent disc spins, and the kit for placing reagent;This evenly mixing device is provided with one or more reagent discs, multiple mounting grooves for placing kit are uniformly provided in each reagent disc, be evenly arranged with multiple by plectrum in kit, be provided with multiple sliding pieces on agent bin, two it is adjacent by between plectrum at least provided with a sliding piece.Driver of the present invention drives tubular container to be rotated around reagent disc, and is driven by plectrum by the sliding piece on agent bin, so that tubular container is rotated around Pivot Point Center, so that the reagent in tubular container is sufficiently mixed and be uniformly mixed;And multiple reagent discs can be arranged in the present invention, and multiple mounting grooves are provided on each reagent disc, can place multiple kits, make the reagent in multiple kits while obtaining mixing, avoid cross-infection.

Description

Evenly mixing device and mixing method
Technical field
The present invention relates to evenly mixing device fields, and in particular to a kind of evenly mixing device and mixing method.
Background technology
In diagnostic instrments reaction, the reagent easily precipitated requires to be in suspended state when using, and distribution is average, tries in this way Agent needle can just obtain uniform quantity when drawing, ensure that reaction mass therefore, need to be by reagent mixing before extracts reagent.It is existing Blending manner:1, mode is shaken up manually, which generally requires half an hour, and the stand-by period is longer;2, mechanical agitation mode, For example stir mix rod under magnetic bead box liquid level, this process needs the mixing arm of a set of individual Telescopic rotary, and It needs cleaning structure to avoid cross contamination between reagent, bumper mixing can also be used, but shake table is complicated, Practice is easy to make mistakes;3, ultrasonic wave agitating mode, this process needs carry out mixing, compare consumption before every use When, and mixed effect cannot be ensured completely;4. mixing bar magnet mode, needed in each reagent bottle plus a bar magnet, magnet is made to exist Outside rotates and bar magnet is driven to rotate, and the reagent position of this mode is few, and cannot be used for the mixing of magnetic reagent.
Invention content
(1) technical problems to be solved
The technical problem to be solved in the present invention is to provide a kind of simple structure, low cost, high efficiency and avoid cross-infection Evenly mixing device.
Extending the uniformly mixed mixing side of mixing duration, guarantee reagent the technical problem to be solved in the present invention is to provide a kind of Method.
(2) technical solution
In order to solve the above technical problems, the present invention provides a kind of evenly mixing device comprising agent bin is movably arranged on reagent Reagent disc in storehouse, the driving device of driving institute reagent disc spins, and the kit for placing reagent;Reagent disc is at least One, it is uniformly provided with multiple mounting grooves for placing kit in each reagent disc, is evenly arranged in kit more It is a multiple sliding pieces are provided with by plectrum on agent bin, two it is adjacent by between plectrum at least provided with a sliding piece.
Wherein, agent bin includes warehouse and the warehouse lid that is fixedly mounted on above warehouse.
Wherein, kit includes reagent box body and is sleeved on the intrinsic tubular container of kit, reagent box body It is multiple to be uniformly arranged on tubular container by plectrum in mounting groove.
Wherein, multiple tops that tubular container is uniformly arranged on by plectrum.
Wherein, multiple sliding pieces are uniformly arranged in warehouse lid.
Wherein, multiple lower sections that tubular container is uniformly arranged on by plectrum.
Wherein, multiple sliding pieces are uniformly arranged on warehouse.
Wherein, the bottom of tubular container is provided with centrum, and the cone of centrum is resisted against the bottom of mounting groove.
A kind of blending manner, includes the following steps:
A, reagent is positioned in tubular container, and tubular container is installed in reagent box body;
B, kit is installed in the mounting groove of reagent disc;
C, driver, drive reagent disc to a direction rotation turns around, then in the same direction or reversely by kit rotate to Nearest absorption position.
(3) advantageous effect
Compared with prior art, driver of the present invention drives tubular container to be rotated around reagent disc, and passes through examination Sliding piece on agent storehouse drives by plectrum, so that tubular container is rotated around Pivot Point Center, the reagent in tubular container is made to be sufficiently mixed And it is uniformly mixed;And multiple reagent discs can be arranged in the present invention, and multiple mounting grooves are provided on each reagent disc, can place more A kit makes the reagent in multiple kits while obtaining mixing, avoids cross-infection.
Description of the drawings
Fig. 1 is that evenly mixing device embodiment one of the present invention removes the dimensional structure diagram after warehouse lid.
Fig. 2 is that evenly mixing device embodiment one of the present invention removes the dimensional structure diagram after warehouse.
Fig. 3 is the horizontal cross-section structure diagram of evenly mixing device embodiment one of the present invention.
Fig. 4 is that evenly mixing device embodiment two of the present invention removes the dimensional structure diagram after agent bin.
Fig. 5 is the dimensional structure diagram that evenly mixing device embodiment two of the present invention removes the other direction after agent bin.
In figure, 1- agent bins;2- reagent discs;3- is by plectrum;4- sliding pieces;5- kits;6- driving devices;11- warehouses; 12- warehouse lids;21- mounting grooves;51- reagent box bodies;52- tubular containers;53- centrums;54- counterbores.
Specific implementation mode
With reference to the accompanying drawings and examples, the specific implementation mode of the present invention is described in further detail.Implement below Example cannot be used for limiting the scope of the invention for illustrating the present invention.
Embodiment one
The stereochemical structure of evenly mixing device of the present invention is as shown in Figure 1 and Figure 2, and cross-section structure is as shown in figure 3, the evenly mixing device Including agent bin 1, the reagent disc 2 being movably arranged in agent bin 1, the driving device 6, Yi Jiyong of 2 rotation of driving institute reagent disc In the kit 5 for placing reagent;Reagent disc 2 is at least one, is uniformly provided in each reagent disc 2 multiple for placing examination The mounting groove 21 of agent box 5, is evenly arranged in kit 5 multiple by plectrum 3, is provided with multiple sliding pieces 4 on agent bin 1, and two It is a it is adjacent by between plectrum 3 at least provided with a sliding piece 4.The quantity of reagent disc is 1, naturally it is also possible to be multiple.
The rotation of multiple reagent discs can be driven by the same driving device, and a driving device driving can also respectively be arranged It is rotated, and the direction of rotation of multiple reagent disc can be identical, may be reversed.
Above-mentioned multiple reagent discs can open up the reagent trough of identical size or shape;Different sizes or shape can also be opened up Reagent trough, to adapt to different kits.
Mentioned reagent storehouse 1 includes warehouse 11 and the warehouse lid 12 for being fixedly mounted on 11 top of warehouse.
Mentioned reagent box 5 includes reagent box body 51 and the tubular container 52 being sleeved in reagent box body 51, reagent Box body 51 is mounted in mounting groove 21, multiple to be uniformly arranged on tubular container 52 by plectrum 3.Reagent disc is in driving device Driving is lower and agent bin generates relative motion, so that the tubular container in kit is generated rotation by plectrum to which sliding piece drives, The plurality of reagents for keeping it internal also generates centrifugal movement, and generates mixing.
It is provided with spoiler in above described tubular container 52, which can be provided in 52 counterbore of tubular container, 54 bottom Tablet, spoiler can be a piece of or multi-disc;The spoiler can also be the spiral plate being molded on 54 inner wall of counterbore.
Above-mentioned multiple tops that tubular container 52 is uniformly arranged on by plectrum 3.
Above-mentioned multiple sliding pieces 4 are uniformly arranged in warehouse lid 12, which is integrally formed in warehouse lid 12.
Above-mentioned sliding piece can be one group, while drive the tubular container in multiple reagent discs;Or it is multigroup, respectively Drive the tubular container in corresponding reagent disc.
Above-mentioned sliding piece can be fixed, and can also be to be driven by related device and rotated.
The bottom of above described tubular container 52 is provided with centrum 53, and the cone of centrum 53 is resisted against the bottom of mounting groove 21, So that tubular container is slightly lifted, significantly reduces resistance when tubular container rotation.
The blending manner of above-mentioned evenly mixing device, includes the following steps:
A, reagent is positioned in tubular container, and tubular container is installed in reagent box body;
B, kit is installed in the mounting groove of reagent disc;
C, driver, drive reagent disc to a direction rotation turns around, then in the same direction or reversely by kit rotate to Nearest absorption position.
Above-mentioned steps A and step B can be exchanged, and this method ensures that the movement duration of reagent disc is enough long, makes tubular container Reagent rotates after fully mixing again to position is drawn, avoid reagent because from draw position it is too close due to cause reagent mixing uneven.
Embodiment two
As shown in Figure 4 and Figure 5, embodiment two and the difference of embodiment one are:It is above-mentioned multiple to be uniformly arranged by plectrum 3 In the lower section of tubular container 52.
Above-mentioned multiple sliding pieces 4 are uniformly arranged on warehouse 11, which is fixedly mounted on warehouse 11.
It these are only the preferred embodiment of the present invention, it is noted that those skilled in the art are come It says, without departing from the technical principles of the invention, several improvements and modifications can also be made, these improvements and modifications are also answered It is considered as protection scope of the present invention.

Claims (2)

1. a kind of evenly mixing device, it is characterised in that:The evenly mixing device includes agent bin (1), is movably arranged on the agent bin (1) reagent disc (2) in, the driving device (6) for driving the reagent disc (2) to rotate, and the kit for placing reagent (5);The reagent disc (2) is multiple, is uniformly provided in each reagent disc (2) multiple for placing the kit (5) mounting groove (21), is evenly arranged on the kit (5) multiple by plectrum (3), is provided on the agent bin (1) Multiple sliding pieces (4), at least provided with a sliding piece (4) between two adjacent (3) by plectrum;
The agent bin (1) includes warehouse (11) and the warehouse lid (12) being fixedly mounted on above the warehouse (11);
The kit (5) includes reagent box body (51) and the tubular container that is sleeved in the reagent box body (51) (52), the reagent box body (51) is mounted in the mounting groove (21), it is multiple it is described be uniformly arranged on by plectrum (3) it is described On tubular container (52);
Multiple tops that the tubular container (52) are uniformly arranged on by plectrum (3), multiple sliding pieces (4) uniformly set It sets in the warehouse lid (12).
2. evenly mixing device according to claim 1, it is characterised in that:The bottom of the tubular container (52) is provided with vertebra The cone of body (53), the centrum (53) is resisted against the bottom of the mounting groove (21).
CN201510305491.5A 2015-06-04 2015-06-04 Evenly mixing device and mixing method Active CN104849130B (en)

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Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
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CN104849130B true CN104849130B (en) 2018-08-21

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Publication number Priority date Publication date Assignee Title
CN105388312B (en) * 2015-12-21 2019-02-01 艾康生物技术(杭州)有限公司 Reagent storage device for fully-automatic analyzer
CN107328948A (en) * 2017-07-27 2017-11-07 宁波海壹生物科技有限公司 A kind of reagent disc and its operating method
CN111207990B (en) * 2020-03-05 2022-10-28 陈红杰 Clinical blood of mechanical type clinical laboratory is from shaking even device

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CN102128939B (en) * 2010-12-31 2012-10-03 安图实验仪器(郑州)有限公司 Regent tray
CN201940244U (en) * 2011-02-14 2011-08-24 四川迈克生物科技股份有限公司 Reagent bin for storing, blending and transferring reagent
CN202460530U (en) * 2012-01-18 2012-10-03 上海蓝怡科技有限公司 Blending device for constant-temperature magnetic particle reagent cup
CN103048479B (en) * 2012-12-13 2014-03-26 江阴泽成生物技术有限公司 Reagent sample system used for full-automatic chemiluminescence analyzer
FR3000803B1 (en) * 2013-01-04 2018-05-25 Immunodiagnostic Systems France ANALYSIS ASSEMBLY FOR ANALYSIS APPARATUS
CN104107647A (en) * 2013-04-16 2014-10-22 深圳迈瑞生物医疗电子股份有限公司 Reagent bottle, device and method for evenly mixing reagent

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Effective date of registration: 20180320

Address after: 315000 Zhejiang city of Ningbo province high tech Zone Seiitsu Road No. 66 building 044 floor 4 East

Applicant after: Ningbo sea one biological technology Co., Ltd.

Address before: 4 building, No. 9, International Exhibition Center, 181 Exhibition Road, Ningbo, Zhejiang 315040, China

Applicant before: Health Biological Medicine Co., Ltd.

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