CN104800540B - Consolidate relieving asthma herbal paste and its preparation process - Google Patents

Abstract

It is provided by the invention it is a kind of have invigorating the lung and the kidney, strengthening the spleen and reducing phlegm improves the drug herbal paste and its preparation process of effect, be my section preventive treatment of disease center after a large amount of clinical practice from intend herbal paste, eliminate the trouble of patient's voluntarily Herb-decocting Method, with curative effect stabilization, efficacy stability, features good taste, easily storage, it is easy to carry, can take for a long time, with respect to Western medicine Small side effects, there is unique advantage in terms of nursing bronchial asthma and chronic respiratory disease.

Description

Consolidate relieving asthma herbal paste and its preparation process

Technical field

The present invention relates to a kind of Chinese herbal ointment formulas prepared using Chinese herbal medicine as raw material, and in particular to a kind of invigorating the lung and the kidney, invigorating the spleen Resolving sputum improves the drug herbal paste and its preparation process of effect.

Background technology

Bronchial asthma is one kind by various kinds of cell（Such as eosinophil, mast cell and T lymphocytes, neutral grain Cell, human airway epithelial cells etc.）The chronic airway inflammation disease participated in cellular component belongs to clinical common chronic multiple Sick difficult disease.This disease recurrent exerbation, it is obstinate refractory, it is touching with the passing of time, even more can secondary many complication, serious threat the public's Life and health and life quality.And modern medicine for the treatment of bronchial asthma non-acute stage of attack mainly to adjust body For the purpose of immunity, enhancing disease resistance, reduction recurrence.Ketotifen or sucking disodium chromoglycate such as can be used, act on machine For system mainly by blocking flow of calcium ions, stabilizing cell membrane inhibits mast cell degranulation etc. to carry out prevention of asthma breaking-out.It is long-acting The imbedibility treatment of β 2 receptor agonist hormone medicine also can significantly alleviate the breaking-out that asthma is seen.Modern medicine is to branch gas Pipe Asthma control means are more, significant effect, however the toxic side effect still difficulty of long-term Inhalation in Treating or systemic administration is difficult to avoid that, Even because the long-time service of hormone medicine leads to the rebound of disease and the reduction of life in patients.In addition, from immunology angle From the point of view of degree, topical anti-inflammatory treatments often ignore the adjustment of whole body, and resistance declines often incurs infection and other side effects again, because This, this diagnosis and treatment scheme can not solve the root problem of bronchial asthma recurrence.

Chronic respiratory disease such as chronic nonspecific inflammation, Chronic Obstructive Pulmonary Disease etc., chronic bronchitis are The chronic nonspecific inflammation of trachea-bronchial epithelial cell mucous membrane and its surrounding tissue, clinically with cough, the symptom based on expectoration, often Year morbidity continues 3 months, continuous 2 years or 2 years or more.Chronic Obstructive Pulmonary Disease（COPD）It is that one group of flow limitation is characterized Pulmonary disease, flow limitation is not fully reversible, in progress sexual development.Because lung function progressive declines, the labor of patient is seriously affected Power and quality of life.According to national urbans in 2006 and the statistical number of the rural area top ten principal disease cause of death, breathing Systemic disease（Do not include lung cancer）The 4th is accounted in the cause of death in city（13.1%）, third position is accounted in rural area（16.4%）. Due to physical and chemical factor caused by atmosphere pollution, smoking, Industrial Economic Development, biotic factor sucking and population ages；Aging etc. Factor makes the incidence for carrying out respiratory disease this year significantly increase, and prevents arduous task.

In recent years, traditional Chinese medicine has obtained certain progress in terms of bronchial asthma is treated, from being not limited solely to The observation of clinical efficacy has more carried out some scientific and precises, fruitful clinical experimental research, is inquiring into Etiologic Mechanism side Face also achieves some breakthroughs.Chinese medicine asthma has a better effect, and Heterosis is in the following aspects： 1. steroids is presently believed to be the effective ways that inflammation is played in control, but oral hormone adverse reaction is more, and is also easy to produce dependence Sense, and the dynamic equilibrium of compound of Chinese herbal medicine asthma from integrally-regulated body is started with, curative effect is lasting and toxicity is relatively low, treats this disease There is some superiority；2. traditional Chinese medicine strengthens the body resistance to consolidate the constitution to the treatment attention of Asthma in Remission Stage, asthma attack number is significantly reduced, is spaced Time lengthening improves the quality of life of patient；It, can be on the basis of endo-medicine 3. the method for traditional Chinese medical herbal treatment asthma is flexible The methods of application, acupuncture and moxibustion therapy being controlled outside upper cooperation, so as to improve and after treatment effect；4. traditional Chinese medicine is reasonably used in due course, Western medicine curative effect can be enhanced, reduce Western medicine dosage and mitigate side effect caused by Western medicine.

Herbal paste as it is a kind of by Traditional medicine infusion, concentration, receive cream and come comparison stiff semi-fluid or semisolid preparation, oneself Just prevented and cured diseases since Gu, righting dispel it is empty, keep fit and healthy, reconcile negative and positive etc. and played positive effect.And herbal paste Tanning process usually requires veteran old docter of TCM's whole process and waits for supervision, can just prepare the herbal paste for having curative effect, this is to city The pharmaceutical factory of fieldization prepares and brings certain difficulty；Patient need to strictly comply with the doctor's request to taking for herbal paste simultaneously, this popularizes herbal paste drug Bring certain difficulty.

Invention content

For the present situation and trend of the prior art, the purpose of the present invention is to provide one kind to consolidate herbal paste of relievining asthma, the herbal paste It is that center is preventiveed treatment of disease in a large amount of clinical practices in my section, under the guidance of differentiation of tcm principle, for bronchial asthma and slowly The pathogenic characteristic of property respiratory disease and the one effective Chinese medicine experience conditioning side summed up.

One kind of the present invention consolidates herbal paste of relievining asthma, it is characterised in that：The drug crude drug includes：Radix Codonopsis, dried orange peel, Radix Astragali, Tendril-leaved fritillary bulb, Rhizoma Atractylodis Macrocephalae, psoralea corylifolia, Poria cocos, Schisandra chinensis, method summer, Semen Cuscutae, lily, windproof, deer horn glue, jujube；Each group distribution ratio share For：225 ~ 300g of Radix Codonopsis, 75 ~ 100g of dried orange peel, 225 ~ 300g of Radix Astragali, 75 ~ 100g of tendril-leaved fritillary bulb, 150 ~ 200g of Rhizoma Atractylodis Macrocephalae, psoralea corylifolia 150 ~ 200g, 225 ~ 300g of Poria cocos, 75 ~ 100g of Schisandra chinensis, 90 ~ 120g of method summer, 150 ~ 200g of Semen Cuscutae, lily 225 ~ 300g are windproof 75 ~ 100g, 150 ~ 200g of deer horn glue, 75 ~ 100g of jujube.

Consolidating herbal paste of relievining asthma has effects that invigorating the lung and the kidney, strengthening the spleen and reducing phlegm, and wherein invigorating the lung and benefiting vital QI has Radix Codonopsis, Radix Astragali.Party Joining has effects that tonifying spleen lung qi, enriches blood, promotes the production of body fluid, it can improve organism adaptation ability and immune function to modern medicine study, increases Strong body also has the function of the respiratory function for improving lung to the tolerance of the stimulations such as high temperature, low temperature, anoxic and fatigue.It is yellow Stilbene energy strengthening spleen and middle warmer, invigorating qi for consolidating superficies, its work with enhancing body body fluid, cellular immunity and improvement lung function of pharmaceutical research With.Semen Cuscutae, psoralea corylifolia in side have the function of warming and invigorating kidney Yang, and Semen Cuscutae energy is nourishing liver and kidney, astringent sperm contracting urine, improving eyesight antidiarrheal, Modern research shows that it can improve macrophages phagocytic capacity, promote lymphocyte transformation, there is Immune enhancement.Psoralen Fat has warming kidney and enhancing yang, receive gas, antidiarrheal the effect of, modern research shows that it is with Zhichuan, enhancing immune function, antibacterial and antiviral Effect.Rhizoma Atractylodis Macrocephalae, dried orange peel, Poria cocos etc. have the effect of invigorating the spleen to dry, wherein dried orange peel energy regulating qi-flowing for strengthening spleen, eliminating dampness and eliminating phlegm, Poria cocos in side It can spleen-benefiting mind-tranquilizing, inducing diuresis for removing edema.The strengthening the spleen and replenishing qi of Rhizoma Atractylodis Macrocephalae energy, eliminating dampness diuresis.Strengthening the spleen and reducing phlegm, the Chinese medicine of warming and invigorating kidney Yang are compatible, energy Play the role of effectively recuperating under medical treatment chronic respiratory disease.

For it is described consolidate herbal paste curative effect stabilization of relievining asthma, efficacy stability, features good taste, easily storage, the present invention also provides A kind of preparation process for consolidating herbal paste of relievining asthma, the preparation process for consolidating herbal paste of relievining asthma mainly include：

Step 1：By drug crude drug Radix Codonopsis, dried orange peel, Radix Astragali, Rhizoma Atractylodis Macrocephalae, psoralea corylifolia, Poria cocos, Schisandra chinensis, the method summer, Semen Cuscutae, If lily, windproof, jujube soak minute；

Step 2：It decocts, decocts 2 hours for the first time in three times, second of decoction 1 hour, third time decocts 1 hour；

Step 3：Decoction liquor filtering will be merged, heating is concentrated into relative density 1.40（20℃）, tendril-leaved fritillary bulb, deer horn glue are mixed Crushing, stirring is to uniform；

Step 4：Deer horn glue, tendril-leaved fritillary bulb after crushing is melt and dissolved in the merging decoction liquor together, cream is received after cooling.

The beneficial effects of the invention are as follows：One kind, which consolidates herbal paste of relievining asthma, has effects that invigorating the lung and the kidney, strengthening the spleen and reducing phlegm, is my section Preventive treatment of disease center after a large amount of clinical practice from the herbal paste intended, eliminate the trouble of patient's voluntarily Herb-decocting Method, tool Effective in cure stabilization, efficacy stability, features good taste, easily storage, it is easy to carry, can take for a long time, with respect to Western medicine Small side effects, There is unique advantage in terms of nursing bronchial asthma and chronic respiratory disease.

Described one kind consolidates herbal paste main pharmacodynamics clinical case of relievining asthma：

Clinical case 1：Patient Mr. Zhou, 54 years old, married, Changsha people from Kaifu District, because of " repeated coughing, cough white sputum More than ten days " come me on December 5th, 2013 and section go to a doctor, are diagnosed as " bronchial asthma ".Patient previously has asthma medical history more than ten Year, the drugs such as fluticasone propionate control symptom is taken certainly, and Morbidity control can.This year easily diseases caused by external factors repeatedly, because cough occurs in flu before more than ten days It the symptoms such as coughs, sneeze, gradually improving after taking paracetamol tablets certainly, still there is cough, occasionally bring up the thicker sputum of white, come me then Section of institute goes to a doctor.Patient repeated coughing coughs up phlegm, no nasal congestion, and stomach is received generally, and two is just fine.Tongue nature is light red, tongue is greasy in vain, and arteries and veins is thin. Dialectical category deficiency of both lung and spleen, qi-asthenia phlegm resistance.Herbal paste conditioning of relievining asthma is consolidated, each 1 time daily morning and evening, 20 ~ 30g is once taken orally, uses Warm water is taken after mixing with liquid, and connection is taken 45 ~ 60 days.Patient coughs after taking herbal paste, coughs up white phlegm significantly reduces, asthma attack time in 1 year Number is reduced, and feels constitution enhancing.

Clinical case 2：Patient Zhao Nvshi, 10 years old, Changsha people from Tianxin District, on November 20th, 2013 was because of " cough, companion's nasal obstruction Flow clear tears 5 days " comes section of our hospital and goes to a doctor, and is diagnosed as " 1. infection of the upper respiratory tracts, 2. bronchial asthmas ".Infant is allergic constitution, is put down Plain sneeze runny nose is continuous, and pharynx is itched, and is frequently hawked, paroxysm of cough from morning, with expectoration, sputum white, stomach receive can, two just adjust it is smooth, tongue Matter is light red, and tongue is greasy in vain, rapid pulse.Patient previously has more than 5 years of bronchial asthma medical history, takes spasmolysis certainly and relievings asthma class drug therapy, symptom Control can.The drug therapies such as patient is anti-inflammatory, antiviral, relieving cough and reducing sputum are given, and is aided with and consolidates herbal paste tonifying lung strengthening the spleen and reducing phlegm of relievining asthma, Improve cough symptom, prevention bronchial asthma recurrence, instructions of taking：Each 1 time daily morning and evening, 20 ~ 30g is once taken orally, is opened with temperature Water is taken after mixing with liquid, and patient's cough and expectoration is reduced after continuously taking 45 ~ 60 days, 2 months, and sneeze runny nose mitigates, and symptom improves.

Clinical case 3：Patient Wang Nvshi, 36 years old, married, Changsha people from Yuelu District, on January 16th, 2014 is because of " nose repeatedly Plug, sneezing, with cough more than half a month " comes section of our hospital and goes to a doctor, and is diagnosed as " bronchial asthma ".Patient previously has bronchial asthma Often there are a symptoms such as nasal obstruction, sneezing, cough before breaking-out every time in more than ten years of history, existing nasal obstruction repeatedly, sneezing symptom be more than half a month, No headache is dizzy, fever with aversion to cold, food intake can, two is just normal, and sleep can.Consolidated herbal paste treatment of relievining asthma, the disease of tonifying lung invigorating the spleen Shape is clearly better, and the asthma of nearly half a year does not recur again, it is proposed that time winter in the coming year continues to take herbal paste treatment.

Clinical case 4：Patient Lin Nvshi, 45 years old, married, Changsha people from Tianxin District, on January 20th, 2014 is because of " cough repeatedly Cough, be uncomfortable in chest, asthma more than 1 year " come section of our hospital and go to a doctor, it is diagnosed as " 1. bronchial asthmas, 2 hypertension ".Patient previously has bronchus Asthma medical history more than 20 years, hypertension history 2 years.Patient's private prosecution is over 1 year repeatedly because cough, chest occur in the factors such as catch a cold, suffer from cold The symptoms such as bored, asthma, occur that uncomfortable in chest, breathing is slightly rapid etc. after coughing 3 ~ 4 days every time, cough up the dilute thick sputum of white, occasionally have pharynx to itch, nothing Nasal obstruction, no dizziness headache take anti-inflammatory agent, relieving asthma shortness of breath after class drug, sense uncomfortable in chest of spasmolysis improves certainly, still when have cough, symptom is anti- Multiple, protracted inflammation is alleviated for general 15 ~ 20 days.To improve constitution, improve section of current state of an illness Te Lai our hospital and go to a doctor, section of our hospital is consolidated Originally herbal paste of relievining asthma improves body, invigorating the lung and the kidney, strengthening the spleen and reducing phlegm.Each 1 time daily morning and evening, 20 ~ 30g is once taken orally, with warm water tune Clothes, continuously take 45 ~ 60 days.It takes after consolidating herbal paste of relievining asthma, nearly half a year asthma does not recur again, the symptoms such as cough, uncomfortable in chest, shortness of breath Attack times significantly reduce.

Clinical case 5：Patient Qiu Xiansheng, 67 years old, married, Changsha people from Yuhua District, on November 11st, 2013 is because of " cough repeatedly Cough, cough up phlegm, shortness of breath more than 1 year " come section of our hospital and go to a doctor, it is diagnosed as " 1. bronchial asthmas, 2. coronary heart disease ".Patient is over nearly 1 year because upper Feel, suffer from cold or the factors such as fatigue cough occur, cough up the symptoms such as the more sticky sputum of white, shortness of breath, take Yanyan slice, ceftazidime piece certainly Symptom is slightly alleviated afterwards, no nasal congestion, no fever with aversion to cold, food intake can, be hard and dry, urine is normal.Patient previously has bronchus Asthma medical history, history of coronary heart disease, existing bronchial asthma state of an illness control can, go to a doctor for section of prevention of asthma disease relapse Te Lai our hospital, Section of our hospital is consolidated herbal paste of relievining asthma and recuperates under medical treatment asthma, the symptoms such as improvement coughs, coughs up phlegm, shortness of breath, each 1 time daily morning and evening, primary mouth 20 ~ 30g is taken, is taken after mixing with liquid with warm water, is continuously taken 45 ~ 60 days.After taking herbal paste, patient tells that nearly half a year asthma does not recur again, body The symptoms such as matter enhances, and upper sense symptom, shortness of breath are uncomfortable in chest improve earlier above, it is proposed that winter in the coming year, which continues to take a course for the treatment of, builds up health.

Specific embodiment

Embodiment 1：

One kind consolidates Pingchuan ointment prescription object composition：Radix Codonopsis 225g, dried orange peel 75g, Radix Astragali 225g, tendril-leaved fritillary bulb 75g, Rhizoma Atractylodis Macrocephalae 150g, Psoralea corylifolia 150g, Poria cocos 225g, Schisandra chinensis 75g, method summer 90g, Semen Cuscutae 150g, lily 225g, windproof 75g, deer horn glue 150g, Jujube 75g.

The preparation process for consolidating herbal paste of relievining asthma mainly includes：

Step 1：It gets it filled object crude drug Radix Codonopsis 225g, dried orange peel 75g, Radix Astragali 225g, Rhizoma Atractylodis Macrocephalae 150g, psoralea corylifolia 150g, Poria cocos If 225g, Schisandra chinensis 75g, method summer 90g, Semen Cuscutae 150g, lily 225g, windproof 75g, jujube 75g soak minute；

Step 2：It decocts, decocts 2 hours for the first time in three times, second of decoction 1 hour, third time decocts 1 hour；

Step 3：Decoction liquor filtering will be merged, heating is concentrated into relative density 1.40（20℃）, take tendril-leaved fritillary bulb 75g, deer horn glue 150g co-grindings are stirred until homogeneous；

Step 4：Deer horn glue, tendril-leaved fritillary bulb after crushing is melt and dissolved in the merging decoction liquor together, cream is received after cooling.

Embodiment 2：

One kind consolidates Pingchuan ointment prescription object composition：Radix Codonopsis 263g, dried orange peel 88g, Radix Astragali 263g, tendril-leaved fritillary bulb 88g, Rhizoma Atractylodis Macrocephalae 175g, Psoralea corylifolia 175g, Poria cocos 263g, Schisandra chinensis 88g, method summer 105g, Semen Cuscutae 175g, lily 263g, windproof 88g, deer horn glue 175g, jujube 88g.

The preparation process for consolidating herbal paste of relievining asthma mainly includes：

Step 1：It gets it filled object crude drug Radix Codonopsis 263g, dried orange peel 88g, Radix Astragali 263g, Rhizoma Atractylodis Macrocephalae 175g, psoralea corylifolia 175g, Poria cocos If 263g, Schisandra chinensis 88g, method summer 105g, Semen Cuscutae 175g, lily 263g, windproof 88g, jujube 88g soak minute；

Step 2：It decocts, decocts 2 hours for the first time in three times, second of decoction 1 hour, third time decocts 1 hour；

Step 3：Decoction liquor filtering will be merged, heating is concentrated into relative density 1.40（20℃）, take tendril-leaved fritillary bulb 88g, deer horn glue 175g co-grindings are stirred until homogeneous；

Step 4：Deer horn glue, tendril-leaved fritillary bulb after crushing is melt and dissolved in the merging decoction liquor together, cream is received after cooling.

Embodiment 3：

One kind consolidates Pingchuan ointment prescription object composition：Radix Codonopsis 300g, dried orange peel 100g, Radix Astragali 300g, tendril-leaved fritillary bulb 100g, Rhizoma Atractylodis Macrocephalae 200g, psoralea corylifolia 200g, Poria cocos 300g, Schisandra chinensis 100g, method summer 120g, Semen Cuscutae 200g, lily 300g, windproof 100g, deer Angle glue 200g, jujube 100g.

The preparation process for consolidating herbal paste of relievining asthma mainly includes：

Step 1：Get it filled object crude drug Radix Codonopsis 300g, dried orange peel 100g, Radix Astragali 300g, Rhizoma Atractylodis Macrocephalae 200g, psoralea corylifolia 200g, Poria cocos 300g, Schisandra chinensis 100g, method summer 120g, Semen Cuscutae 200g, lily 300g, windproof 100g, if jujube 100g soaks minute；

Step 2：It decocts, decocts 2 hours for the first time in three times, second of decoction 1 hour, third time decocts 1 hour；

Step 3：Decoction liquor filtering will be merged, heating is concentrated into relative density 1.40（20℃）, take tendril-leaved fritillary bulb 100g, deer horn glue 200g co-grindings are stirred until homogeneous；

Step 4：Deer horn glue, tendril-leaved fritillary bulb after crushing is melt and dissolved in the merging decoction liquor together, cream is received after cooling.

Claims (2)

1. one kind consolidates herbal paste composition of relievining asthma, it is characterised in that：The herbal paste drug crude drug：Radix Codonopsis, dried orange peel, Radix Astragali, river Shellfish, Rhizoma Atractylodis Macrocephalae, psoralea corylifolia, Poria cocos, Schisandra chinensis, method summer, Semen Cuscutae, lily, windproof, deer horn glue, jujube；Each group distribution ratio share For：225~300g of Radix Codonopsis, 75~100g of dried orange peel, 225~300g of Radix Astragali, 75~100g of tendril-leaved fritillary bulb, 150~200g of Rhizoma Atractylodis Macrocephalae, psoralea corylifolia 150~200g, 225~300g of Poria cocos, 75~100g of Schisandra chinensis, 90~120g of method summer, 150~200g of Semen Cuscutae, lily 225~ 300g, windproof 75~100g, 150~200g of deer horn glue, 75~100g of jujube.

2. one kind according to claim 1 consolidates herbal paste composition of relievining asthma, preparation process is characterized in that：The preparation Technique is mainly：

Step 1：By drug crude drug Radix Codonopsis, dried orange peel, Radix Astragali, Rhizoma Atractylodis Macrocephalae, psoralea corylifolia, Poria cocos, Schisandra chinensis, method summer, Semen Cuscutae, hundred It closes, if windproof, jujube soaks minute；

Step 2：It decocts, decocts 2 hours for the first time in three times, second of decoction 1 hour, third time decocts 1 hour；

Step 3：Decoction liquor filtering will be merged, heating is concentrated into 20 DEG C of relative densities 1.40, tendril-leaved fritillary bulb, deer horn glue co-grinding are stirred It mixes to uniform；

Step 4：Deer horn glue, tendril-leaved fritillary bulb after crushing is melt and dissolved in the merging decoction liquor together, cream is received after cooling.