CN104792744A - Terahertz wave focusing device - Google Patents

Terahertz wave focusing device Download PDF

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Publication number
CN104792744A
CN104792744A CN201510185887.0A CN201510185887A CN104792744A CN 104792744 A CN104792744 A CN 104792744A CN 201510185887 A CN201510185887 A CN 201510185887A CN 104792744 A CN104792744 A CN 104792744A
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thz wave
micro
lens
recovery
fluidic chip
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CN201510185887.0A
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CN104792744B (en
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张中卫
朱亦鸣
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University of Shanghai for Science and Technology
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University of Shanghai for Science and Technology
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Abstract

The invention provides a terahertz wave focusing device, which helps to detect ingredients of micro-fluid in a micro-fluidic chip microchannel. The terahertz wave focusing device comprises a light source part, a focusing part, a to-be-measured part, a recovering part and a collecting part, wherein the light source part is used for introducing ordinary terahertz wave into the focusing device; the focusing part comprises a focusing lens and a first metal wire; the to-be-measured part comprises a micro-fluidic chip; the recovering part comprises a recovering lens for recovering the terahertz wave and a second metal wire; the collecting part is used for collecting the recovered terahertz wave; at least two first circular grooves with the sub-wavelength size are formed in the first metal wire; the space between the at least two first circular grooves is decreased progressively in the terahertz wave propagation direction; second circular grooves with the sub-wavelength size correspond to the first circular grooves in quantity and are formed in the second metal wire; the space between the at least two second circular grooves is increased progressively in the terahertz wave propagation direction. The terahertz wave focusing device disclosed by the invention is used for helping to detect the micro-fluid in the designated single microchannel of the micro-fluidic chip.

Description

THz wave focalizer
Technical field
The invention belongs to detection technique field, being specifically related to a kind of THz wave focalizer for detecting the micro liquid in microchannel.
Background technology
THz wave is the electromagnetic wave of frequency in 0.1THz to 10THz scope, because it is low and the characteristic such as not easily to be absorbed that THz wave has energy, penetrability due to THz ray and the strong reflection characteristic to metal material, and the high-frequency of THz makes the resolution of imaging higher, so, can be easy to see hiding article, in addition, in conjunction with the material identification feature of THz, utilize the very abundant physics and chemistry information that THz wave detection material can obtain about material, have broad application prospects so utilize THz wave to carry out detection to material.
In prior art, for some moisture materials in order to detect, saving sample use amount fast, usual employing microfluidic chip technology, because micro-fluidic chip can realize from sample preparation, biological and chemical reaction, be separated with detection etc. that basic operation is integrated completes.But, girdling the waist of existing spontaneous common THz wave is too thick, general waist radius is millimetre-sized, and the width of microchannel in micro-fluidic chip and the degree of depth are all generally micron orders, if adopt common THz wave to detect, then can cover all passages, cannot realize only covering a dedicated tunnel, thus restriction THz wave detect the application on micro-fluidic chip.
Summary of the invention
The present invention carries out to solve above-mentioned problem, and object is to provide a kind of THz wave focalizer for detecting micro liquid in microchannel.
The invention provides a kind of THz wave focalizer, utilize the micro liquid that common THz wave is come in auxiliary detection microchannel, it is characterized in that, comprising: light source portion, for introducing THz wave, focus portion, is located in the light path of THz wave, comprises: for first tinsel at the condenser lens that focuses on THz wave and the center through condenser lens, portion to be measured, comprises: be provided with at least one be focused after the micro-fluidic chip of microchannel that passes of THz wave, recovery portion, for restoring through the THz wave after micro-fluidic chip, comprises: center recovery lens for restore THz wave corresponding with the center of condenser lens and pass second tinsel at the center of restoring lens, and test section, for detecting by the THz wave of restoring, wherein, first tinsel has the first ring groove of at least two sub-wavelength dimensions structures, spacing between at least two the first ring grooves is successively decreased along Terahertz direction of wave travel, second tinsel has the second ring groove of the sub-wavelength dimensions structure corresponding with the quantity of the first ring groove, spacing between at least two the second ring grooves increases progressively along Terahertz direction of wave travel, THz wave is after condenser lens and the focusing of the first tinsel are focused, through micro-fluidic chip, then THz wave is restored by the second tinsel and recovery lens, test section detects the THz wave after recovery.
In THz wave focalizer provided by the invention, also such feature can be had, also comprise: location division, for position of focusing facula portion and recovery portion, comprise: optical bench and be fastened on moveable three fixture blocks on optical bench, wherein, one sidewall of optical bench is evenly provided with scale mark, focus portion, portion to be measured and restoring part are not fixed on three fixture blocks, regulate the position of fixture block, make the microchannel of micro-fluidic chip be in the minimum place of waist radius of THz wave.
In THz wave focalizer provided by the invention, can also have such feature: wherein, fixture block comprises: wherein, and portion to be measured also comprises mount pad, and mount pad makes micro-fluidic chip level or is vertically arranged on fixture block.
In THz wave focalizer provided by the invention, can also have such feature: wherein, mount pad comprises the holder of hinge-type.
In THz wave focalizer provided by the invention, such feature can also be had: wherein, condenser lens and recovery lens are all hemispherical shape, be provided with in the center of condenser lens towards the solid angle of the centre of sphere opening of condenser lens, be provided with towards the solid angle of the centre of sphere opening restoring lens in the center of restoring lens.
In THz wave focalizer provided by the invention, such feature can also be had: wherein, body also comprises: wherein, focus portion also comprises the first support bar for fixed support condenser lens and telescopic first sleeve, first sleeve is fixed on fixture block, first support bar inserts in the first sleeve, recovery portion also comprises and restores the second support bar of lens and telescopic second sleeve for fixed support, second sleeve is fixed on fixture block, and the second support bar inserts in the second sleeve.
The effect of invention and effect
According to THz wave focalizer involved in the present invention, because the condenser lens of focus portion focuses on THz wave, and the first ring groove of the sub-wavelength dimensions structure of being successively decreased by the spacing on the first tinsel, THz wave is made to realize efficient focusing, THz wave after focusing is through the micro-fluidic chip in portion to be measured, THz wave after setting focuses on only covers a microchannel in micro-fluidic chip thus realizes detecting the transmission of fluid in microchannel, then, the THz wave passed from micro-fluidic chip is restored by the second ring groove of the sub-wavelength dimensions structure that the spacing the recovery lens in recovery portion and the second tinsel increases progressively, test section detects the THz wave after recovery, so, THz wave focalizer of the present invention realizes effectively detecting micro liquid in the single microchannel on micro-fluidic chip.
Accompanying drawing explanation
Fig. 1 is the structural representation of THz wave focalizer in embodiments of the invention; And
Fig. 2 is the process flow diagram of THz wave focalizer in embodiments of the invention.
Concrete case study on implementation
The technological means realized to make the present invention, creation characteristic, reach object and effect is easy to understand, following examples are specifically addressed THz wave focalizer of the present invention by reference to the accompanying drawings.
Fig. 1 is the structural representation of THz wave focalizer in embodiments of the invention.
As shown in Figure 1, in the present embodiment, THz wave focalizer 100 for detecting the fluid in microchannel, and can only covering one specify microchannel to carry out transmission detection.THz wave focalizer 100 comprises: light source portion 10, focus portion 20, portion to be measured 30, recovery portion 40, location division 50 and test section 60.
Location division 50 is for position of focusing facula portion 20, portion to be measured 30 and recovery portion 40, and location division 50 comprises: optical bench 51, fixture block 52, fixture block 53 and fixture block 54.Fixture block 52, fixture block 53 and fixture block 54 are movably fastened on optical bench 51.Focus portion 20, portion to be measured 30 and recovery portion 40 respectively one_to_one corresponding are fixed on fixture block 52, fixture block 53 and fixture block 54.
Light source portion 10, for sending THz wave, arranges focus portion 20, portion to be measured 30, recovery portion 40 and test section 60 respectively on the THz wave direction of propagation.
Focus portion 20 is for focusing on THz wave, and the waist radius of THz wave is reduced, and focus portion 20 comprises: condenser lens 21, first support bar 22, first sleeve 23 and the first tinsel 24.First support bar 22 inserts in the first sleeve 23, and the first support bar 22 is for installing condenser lens 21, and the first tinsel 23 is through the center of condenser lens 21.
The THz wave that condenser lens 21 sends for focused light source portion 10, condenser lens 21 is in super-hemispherical, and wherein the diameter of the large disk of condenser lens 21 is 110mm.Placed towards light source portion 10 by the large disk of condenser lens 21, the focal length of condenser lens 21 is continuously adjustable in 0.314um to 4.19um scope, realizes changing focal length by the curve changing condenser lens 21.In addition, the center of condenser lens 21 has the pyramid type solid angle of the minute surface centre of sphere opening towards condenser lens 21, namely with the direction in Fig. 1, the opening of this pyramid type solid angle is towards the left side, this pyramid type cube corner structures can assist convergence THz wave, and the waist radius of THz wave is diminished further.Be provided with the threaded hole for being fixedly mounted on the first base 25 in the bottom of condenser lens 21 near large disk place, condenser lens 21 is adopt silicon lens in the present embodiment.
First sleeve 23 is fixed on fixture block 52, first support bar 22 to be inserted in the first sleeve 23 and is fixed by screw, first support bar 22 is provided with the screw matched with the threaded hole of condenser lens 21, condenser lens 21 can be fixed by screws on the first support bar 22, and pass through the length of adjustment first sleeve 23 thus the position of the vertical direction of adjustment condenser lens 21.
The diameter of the first tinsel 23 is 1mm, long 7.5cm, first tinsel 23 is etched with the first ring groove of multiple sub-wavelength dimensions structure, the plurality of first ring groove is closely adjacent to each other and has certain interval between groove and groove, spacing between first ring groove is successively decreased on the direction of propagation of the first tinsel 23 along THz wave, the surface plasma excimer ripple that this structure makes the surface of the first tinsel 23 produce and THz wave produce resonance, thus THz wave is limited in local scope effectively, realize efficiently focusing on.First tinsel 23 is copper wires in the present embodiment.
Portion 30 to be measured is located between focus portion 20 and recovery portion 40, and portion 30 to be measured comprises: micro-fluidic chip 31 and mount pad 32.THz wave after focus portion 20 focuses on is through micro-fluidic chip 31.Mount pad 32 makes micro-fluidic chip 31 level or vertically places.There are at least two microchannels of bonding micro-fluidic chip 31 inside, and fluid to be measured flows in this microchannel.Mount pad 32 comprises holder 32a, the 3rd sleeve 32b.3rd sleeve 32b is fixed on fixture block 53, and holder 32a to be inserted in the 3rd sleeve 32b and fixed by screw.Holder 32a is hinge-type, clamps micro-fluidic chip 31 and be fixed by the trip bolt of holder 32a by the hinge of holder 32a, and holder 32a both can make micro-fluidic chip 31 vertically place, and also can make micro-fluidic chip 21 horizontal positioned.
Recovery portion 40 is for restoring the waveform of the THz wave through micro-fluidic chip 31, and recovery portion 40 comprises: restore lens 41, second support bar 42, second sleeve 43 and the second tinsel 44.Second support bar 42 inserts in the second sleeve 43, and the second support bar 42 restores lens 41, second tinsel 44 through the center of restoring lens 41 for installing.Restore lens 41 similar to the structure of condenser lens 42, omit associated description at this.The large disk backlight portion 10 restoring lens 41 being placed, restoring lens 41 for being restored by the waveform of THz wave.Second sleeve 43 is fixed on fixture block 54, second support bar 42 to be inserted in the second sleeve 43 and is fixed by screw, second support bar 42 is provided with the screw matched with the threaded hole restoring lens 41, recovery lens 41 can be fixed by screws on the second support bar 42, and pass through the length of adjustment second sleeve 43 thus the position of the vertical direction of adjustment recovery lens 41.
The diameter of the second tinsel 44 is 1mm, long 7.5cm, second tinsel 44 is etched with the second ring groove of multiple sub-wavelength dimensions structure, the plurality of second ring groove is closely adjacent to each other and spacing between the second ring groove increases progressively on the direction of propagation of the second tinsel 44 along THz wave, and the second tinsel 44 produces the recovery that surface plasmons strengthens THz wave when propagating THz wave.Second tinsel 44 is copper wires in the present embodiment.
One sidewall of the optical bench 51 of location division 50 is evenly provided with scale mark.Fixture block 52, fixture block 53 and fixture block 54 have mark pointer 52a, mark pointer 53a, mark pointer 54a respectively.By regulating the position of fixture block 52, fixture block 53 and fixture block 54 thus the distance regulating condenser lens 21, micro-fluidic chip 31 and restore between lens 41, make the microchannel of micro-fluidic chip 41 just be in the minimum place of waist radius of the THz wave after focusing, realize THz wave through the microchannel of specifying.In addition, by the position that mark pointer 52a, mark pointer 53a, the mark pointer 54a scale mark on the sidewall of optical bench 51 is pointed out, the distance relation that accurately can read condenser lens 21, micro-fluidic chip 31 and restore between lens 41, thus be convenient to the waist radius size regulating THz wave.
Test section 60 is for detecting the THz wave of the recovery behind recovery portion 40, after this THz wave have passed through the fluid of microchannel in micro-fluidic chip 31, test section 60 detects this THz wave thus obtains the physics and chemistry information of fluid, in the present embodiment, test section 60 is terahertz time-domain system.
Fig. 2 is the process flow diagram of THz wave focalizer in embodiments of the invention.
As shown in Figure 2, THz wave focalizer 100 test fluid of the present embodiment, concrete steps are as follows:
Step S1, light source portion 10 sends THz wave, then enters step S2.
Step S2, focus portion 20 pairs of THz wave focus on, the distance first regulating condenser lens 21, micro-fluidic chip 31 and restore between lens 41, makes the microchannel of micro-fluidic chip 31 be in the minimum place of waist radius of the THz wave after focusing, then enters step S3.
Step S3, the THz wave after focusing, through the liquid of specifying microchannel in micro-fluidic chip 31, then enters step S4.
Step S4, recovery portion 40 restores the THz wave through micro-fluidic chip 31, THz wave is by the second tinsel 44 and be restored to first trial waveform after restoring lens 41, and the THz wave after recovery can be received by the receiver of terahertz time-domain system, then enters step S5.
Step S5, test section 60 is collected with the THz wave after the recovery of sample message, the THz wave collected can be received by the receiver of terahertz time-domain system, terahertz time-domain system is by analyzing the time difference between pump light and detection light, realize the detection to the micro liquid of specifying microchannel in micro-fluidic chip, obtain the physics and chemistry information of this liquid, then enter done state.
The waist radius of the THz wave focused on by focus portion 20 can reach micron order, thus makes THz wave only cover an appointment microchannel, realizes the detection of THz wave for micro-fluidic chip 31.
The effect of embodiment and effect
THz wave focalizer involved by the present embodiment, because the condenser lens degree THz wave of focus portion focuses on, and the first ring groove of the sub-wavelength dimensions structure of being successively decreased by the spacing on the first tinsel, THz wave is made to realize efficient focusing, THz wave after focusing is through the micro-fluidic chip in portion to be measured, THz wave after setting focuses on only covers a microchannel in micro-fluidic chip thus the detection realized micro liquid in microchannel, then, the second ring groove that the THz wave passed from micro-fluidic chip is increased progressively by the spacing the recovery lens in recovery portion and the second tinsel restores, test section detects the THz wave after recovery, therefore, the THz wave focalizer of the present embodiment realizes effectively detecting fluid in the single microchannel on micro-fluidic chip.
In the present embodiment, because condenser lens, micro-fluidic chip and recovery lens can regulate on optical bench, therefore, the present embodiment can focus on THz wave more easily, and makes the microchannel of micro-fluidic chip be in the minimum place of waist radius of THz wave.
In the present embodiment, because the holder in portion to be measured can fix micro-fluidic chip in horizontal or vertical direction, therefore, the present embodiment detects more easily to micro liquid sample in micro-fluidic chip.
In the present embodiment, because condenser lens and recovery lens have pyramid type solid angle, therefore, in the present embodiment, the pyramid type solid angle of condenser lens is auxiliary converges THz wave, restores the pyramid type solid angle auxiliary recovery THz wave waveform of lens.
Above-mentioned embodiment is preferred case of the present invention, is not used for limiting the scope of the invention.
The present invention can detect the micro liquid in portion to be measured, also can detect other material, as minimum gas.

Claims (6)

1. a THz wave focalizer, utilizes the micro liquid that common THz wave is come in auxiliary detection microchannel, it is characterized in that, comprising:
Light source portion, for introducing described THz wave;
Focus portion, is located in the light path of described THz wave, comprises: for first tinsel at the condenser lens that focuses on described THz wave and the center through described condenser lens;
Portion to be measured, comprises: be provided with at least one be focused after the micro-fluidic chip of described microchannel that passes of described THz wave;
Recovery portion, for restoring through the described THz wave after described micro-fluidic chip, comprise: second tinsel at center recovery lens for restore described THz wave corresponding with the center of described condenser lens and the center through described recovery lens; And
Test section, for detecting by the described THz wave of restoring,
Wherein, described first tinsel has the first ring groove of at least two sub-wavelength dimensions structures, the spacing between at least two described first ring grooves is successively decreased along described Terahertz direction of wave travel,
Described second tinsel has the second ring groove of the sub-wavelength dimensions structure corresponding with the quantity of described first ring groove, and the spacing between at least two described second ring grooves increases progressively along described Terahertz direction of wave travel,
Described THz wave is after described condenser lens and described first tinsel focusing are focused, through described micro-fluidic chip, then described THz wave is restored by described second tinsel and described recovery lens, and described test section detects the described THz wave after recovery.
2. THz wave focalizer according to claim 1, is characterized in that, also comprise:
Location division, for locating described focus portion and described recovery portion, comprises: optical bench and be fastened on moveable three fixture blocks on described optical bench,
Wherein, a sidewall of described optical bench is evenly provided with scale mark,
Described focus portion, described portion to be measured and described restoring part are not fixed on described three fixture blocks,
Regulate the position of described fixture block, make the microchannel of described micro-fluidic chip be in the minimum place of waist radius of described THz wave.
3. THz wave focalizer according to claim 2, is characterized in that:
Wherein, described portion to be measured also comprises mount pad, and described mount pad makes described micro-fluidic chip level or is vertically arranged on described fixture block.
4. THz wave focalizer according to claim 3, is characterized in that:
Wherein, described mount pad comprises the holder of hinge-type.
5. THz wave focalizer according to claim 1, is characterized in that:
Wherein, described condenser lens and described recovery lens are all hemispherical shape,
Be provided with in the center of described condenser lens towards the solid angle of the centre of sphere opening of described condenser lens,
Be provided with towards the solid angle of the centre of sphere opening of described recovery lens in the center of described recovery lens.
6. THz wave focalizer according to claim 2, is characterized in that:
Wherein, described focus portion also comprises the first support bar for condenser lens described in fixed support and telescopic first sleeve,
Described first sleeve is fixed on described fixture block, and described first support bar inserts in described first sleeve,
Described recovery portion also comprises the second support bar for restoring lens described in fixed support and telescopic second sleeve,
Described second sleeve is fixed on described fixture block, and described second support bar inserts in described second sleeve.
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CN113528343B (en) * 2021-07-19 2022-08-02 中国科学院重庆绿色智能技术研究院 Adherent cell culture device for terahertz wave irradiation

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