CN104791985B - A kind of iodate oil heating unit - Google Patents

A kind of iodate oil heating unit Download PDF

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Publication number
CN104791985B
CN104791985B CN201510177338.9A CN201510177338A CN104791985B CN 104791985 B CN104791985 B CN 104791985B CN 201510177338 A CN201510177338 A CN 201510177338A CN 104791985 B CN104791985 B CN 104791985B
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China
Prior art keywords
heating
chip microcomputer
liquid crystal
temperature
crystal display
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Expired - Fee Related
Application number
CN201510177338.9A
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Chinese (zh)
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CN104791985A (en
Inventor
马小桔
葛雪燕
李冠海
张明德
独建库
杨金炜
冯聪勤
黄咏梅
赵鹏举
吴英超
姚智强
刘献茹
陈凤凤
李小兵
庄明军
胡趁晓
赵玲艳
周义娜
梁涵涵
张蓉
贾艳
智慧
王璐
梁英
林汉英
陈晓玲
刘智文
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NO150 CENTRAL HOSPITAL PLA
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NO150 CENTRAL HOSPITAL PLA
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Expired - Fee Related legal-status Critical Current
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Abstract

A kind of iodate oil heating unit, is related to a kind of medical iodized oil heater, the upper end of heating muff is arranged on housing(9)On, it is provided with heating tube in the space outside of heating muff(13), the heating tube passes through connection single-chip microcomputer(14), closed up in the lower end of the heating muff provided with lower(16), temperature sensor(17)Upper end is at the lower closing in, and temperature sensor is by connection single-chip microcomputer, in the panel that housing is anterior(12)It is provided with single-chip microcomputer controlling organization and liquid crystal display(1), attaching plug of the housing provided with connection single-chip microcomputer(8);The present invention controls the heating of iodized oil by single-chip microcomputer, and the heating-up temperature that effectively prevent prior art iodized oil is difficult to control problem.

Description

A kind of iodate oil heating unit
Technical field
The present invention relates to a kind of medical iodized oil heater, more particularly, to a kind of iodate oil heating unit.
Background technology
Known, iodized oil is needed to use when treating some case histories;Iodized oil is clinically the most frequently used middle effect embolism Agent, there is 10% and 40% two kind of formulation.Fat-soluble medicine is can dissolve, or emulsion is made with water soluble drug.Iodized oil is conduct Suppository, is good pharmaceutical carrier again, with guiding and embolism double action, and is easy to CT follow-ups check after treatment.Iodine The emulsifying agent that carburetion is made with chemotherapeutics, is optionally muchly trapped in liver cancer tissue, is killed by embolism and chemotherapy Impariment of the liver cancer cell.It is now recognized that iodized oil is optionally trapped in liver cancer tissue, the mainly rainbow by nourishing liver cancer blood vessel Suction is acted on;Blood vessel dilatation is tortuous in liver cancer tissue;Liver cancer tissue lacks innervation;Liver cancer tissue vasopermeability is high, lipiodol Liver cancer tissue gap is easily penetrated into, or even in liver cancer cells;Liver cancer tissue lacks monocyte system and lymphatic return removes lipiodol Particle.But found in treatment clinical course, and liver cancer type all Accumulations of not all.Wherein it should be noted that infiltrative type liver Cancer, diffusion-type liver cancer, many tubercle pattern of fusion liver cancer, massive hepatocarcinoma, without pseudocapsule liver cancer and the weary blood fortune type liver of hepatic arteriography The poly- iodine of cancer is poor, even not poly- iodine.Whether the poly- iodine of liver cancer tissue to be, in addition to above-mentioned factor also with liver cancer type, size and liver cancer group Knit structure relevant [W uses 1].
In application iodized oil, hyperpyrexia iodized oil is invented by the Clinical Medical Institute Li Xuan of Peking University the 3rd.It is by iodized oil 110 DEG C of injection arteria hepaticas are heated to, chemotherapy, thermotherapy and embolism are combined, while embolism chemical therapeutic, cause liver cancer to nourish again Blood vessel internal membrane damage, occlusion, liver cancer embolism are more thorough.[W with 2] is successfully used for clinic, and achieves preferable curative effect. MMCms-CDDP monoiod(in)ates oil multiphase emulsion is that MMC, CDDP and iodized oil are made into multiphase emulsion, utilizes drug delivery technologies Two kinds of chemotherapeutics in multiphase emulsion is discharged in different phases, make full use of chemotherapeutics, more effectively killing liver cancer is thin Born of the same parents.This method is also invented by Li Xuan, and is used successfully to clinical [W uses 3].
In the application of above-mentioned hyperpyrexia iodized oil, iodized oil is heated by alcolhol burner or other heating means mostly, so Not only it is difficult to the preferred temperature for grasping iodized oil, and phenomenon too high or too low for temperature easily occurs, is unfavorable for the grasp of doctor; Also occur by retrieving domestic patent document, academic journal and market survey without special iodate oil heating unit.
The content of the invention
In order to overcome the shortcomings of in background technology, the present invention discloses a kind of iodate oil heating unit, passes through single-chip microcomputer control The heating of iodized oil, the heating-up temperature that effectively prevent prior art iodized oil is difficult to control problem.
For achieving the above object, the present invention is adopted the following technical scheme that:
A kind of iodate oil heating unit, including housing, single-chip microcomputer, heating muff, heating tube, temperature sensor and liquid crystal Show device, the upper end of heating muff is arranged on housing, be provided with heating tube in the space outside of heating muff, the heating tube passes through Connection single-chip microcomputer, closes up, temperature sensor upper end is at the lower closing in the lower end of the heating muff provided with lower, Temperature sensor is provided with single-chip microcomputer controlling organization and liquid crystal display by connection single-chip microcomputer on the anterior panel of housing Device, attaching plug of the housing provided with connection single-chip microcomputer.
Described iodate oil heating unit, the heating muff includes heating muff A and heating muff B two, in heating Sleeve A and heating muff B outside are interval with heating tube respectively, and two heating tube passes through circuit and the connecting seat of single-chip microcomputer Connection, single-chip microcomputer controlling organization and liquid crystal display are provided with the anterior panel 12 of housing.
Described iodate oil heating unit, the controlling organization set on panel includes liquid crystal display, menu setecting and pressed Key, menu reset key, temperature heighten button and temperature turns down button, and the liquid crystal display is provided with two pieces of correspondence heating mantles Pipe A and heating muff B temperature display device mouthful, menu setecting button, menu reset key, temperature heighten button and temperature is turned down Button is arranged on the surrounding any part of liquid crystal display.
Described iodate oil heating unit, power switch, power supply are provided with the surrounding any part of the liquid crystal display The switch connection single-chip microcomputer.
Described iodate oil heating unit, warning lamp, warning lamp are provided with the surrounding any part of the liquid crystal display Connect the single-chip microcomputer.
Described iodate oil heating unit, is provided with support bar, the support bar lower end is fixed in the bottom of temperature sensor On Housing Base.
Due to using technical scheme as described above, the present invention has the advantages that:
Iodate oil heating unit of the present invention, the heating tube outside heating muff is controlled by single-chip microcomputer, and by temperature Degree sensor and liquid crystal display know the constantly heating-up temperature of iodized oil in time;Present invention effectively prevents prior art iodate The heating-up temperature of oil is difficult to control problem, obtains thermal-stable, the technique effect effect of temperature-controllable of iodized oil.
【Brief description of the drawings】
Fig. 1 is the structural representation of the present invention;
Fig. 2 is the internal structure schematic diagram of the present invention;
In figure:1st, liquid crystal display;2nd, menu setecting button;3rd, menu reset key;4th, temperature heightens button;5th, power supply Switch;6th, temperature turns down button;7th, warning lamp;8th, attaching plug;9th, housing;10th, heating muff A;11st, heating muff B;12、 Panel;13rd, heating tube;14th, single-chip microcomputer;15th, connecting seat;16th, it is lower to close up;17th, temperature sensor;18th, support bar.
【Embodiment】
The present invention can be explained in more detail by the following examples, the invention is not limited in the following examples;
Iodate oil heating unit with reference to described in accompanying drawing 1 or 2, including housing 9, single-chip microcomputer 14, heating muff, heating tube 13rd, temperature sensor 17 and liquid crystal display 1, the upper end of heating muff is arranged on housing 9, in the space outside of heating muff Provided with heating tube 13, the heating tube 13 is closed up by connection single-chip microcomputer 14 in the lower end of the heating muff provided with lower 16, the upper end of temperature sensor 17 is at the lower closing in 16, and support bar 18, the branch are provided with the bottom of temperature sensor 17 The lower end of strut 18 is fixed on the bottom plate of housing 9, and temperature sensor 17 is by connection single-chip microcomputer 14, in the face that housing 9 is anterior Plate 12 is provided with the controlling organization of single-chip microcomputer 14 and liquid crystal display 1;Or the heating muff is set to two sets, including heating muff A10 and heating muff B11 two, heating tube 13, institute are interval with heating muff A10 and heating muff B11 outside respectively State two heating tubes 13 to be connected with the connecting seat 15 of single-chip microcomputer 14 by circuit, single-chip microcomputer is provided with the anterior panel 12 of housing 9 14 controlling organizations and liquid crystal display 1, attaching plug 8 of the housing 9 provided with connection single-chip microcomputer 14.
Further, the controlling organization set on panel 12 includes liquid crystal display 1, menu setecting button 2, menu and resetted Button 3, temperature heighten button 4 and temperature turns down button 6, the liquid crystal display 1 provided with two pieces of correspondence heating muff A10 and Heating muff B11 temperature display device mouthful " temperature display device mouthful is set according to the setting quantity of heating muff ", menu setecting is pressed Key 2, menu reset key 3, temperature heighten button 4 and temperature turns down any portion of surrounding that button 6 is arranged on liquid crystal display 1 Position, power switch 5 and warning lamp 7, the power switch 5 and warning are provided with the surrounding any part of the liquid crystal display 1 Lamp 7 connects the single-chip microcomputer 14.
Implement iodate oil heating unit of the present invention, in use, making energization of the present invention using attaching plug 8, will fill Enter container iodized oil " container be teat glass or do not interfere with theory iodized oil heating after quality metal tube " be put into plus Thermal sleeve, limits container height by the lower closing in 16 of heating muff bottom, at this moment turns on the power switch 5, dish is adjusted as needed Single selection key 2 makes heating muff A10 heating tube 13 and heating muff B11 heating tube 13 while being powered or therein any Heating tube 13 is powered, and heightens button 4 by temperature or temperature is turned down button 6 and adjusted to suitable temperature range, starts in container Iodized oil heating, at this moment temperature display device mouthful of the temperature sensor 17 constantly by vessel temp in liquid crystal display 1 is shown, is held When iodized oil heating-up temperature in device reaches setting value, warning lamp 7, which flashes, just can remove the heating that container completes iodized oil.
The present invention reaches 110 DEG C of iodate oil suspension after heating(MMCms—CDDP)From conduit injection, target area is reached Iodate oil suspension temperature is about 42 DEG C~45 DEG C.Research shows:
1), 42 DEG C~43 DEG C of temperature have lethal effect to tumour cell and to normal impact cell less, therefore, the temperature Degree is safely and effectively to treat temperature.
2), heating preparation can increase local tumor vessel permeability in target site, play chemotherapeutics maximum Killing tumor cell effect.
3), two kinds of chemotherapeutics discharged in different phases, make full use of chemotherapeutics, more effectively killing liver cancer is thin Born of the same parents.
4), small l2 J of lipiodol viscosity after heating, be easier to enter Surrounding Hepatocarcinoma portal vein by hepatic carcinoma blood circulation, So as to reach arteria hepatica, the purpose of portal vein combined embolization.
Make more thorough, the speed and degree of increasing hypoxic tumor cell ischemic necrosis that tumour blood supply is blocked.
Part not in the detailed description of the invention is prior art.

Claims (5)

1. a kind of iodate oil heating unit, including housing(9), single-chip microcomputer(14), heating muff, heating tube(13), TEMP Device(17)And liquid crystal display(1), it is characterized in that:The upper end of heating muff is arranged on housing(9)On, in the outside of heating muff It is interval with heating tube(13), the heating tube(13)Pass through connection single-chip microcomputer(14), in the lower end of the heating muff Closed up provided with lower(16), temperature sensor(17)Upper end is in the lower closing in(16)Place, temperature sensor(17)Pass through circuit Connect single-chip microcomputer(14), in housing(9)Anterior panel(12)It is provided with single-chip microcomputer(14)Controlling organization and liquid crystal display (1), the housing(9)Provided with connection single-chip microcomputer(14)Attaching plug(8);
Further, the heating muff includes heating muff A(10)With heating muff B(11)Two, in heating muff A(10)With Heating muff B(11)Outside be interval with heating tube respectively(13), two heating tube(13)Pass through circuit and single-chip microcomputer (14)Connecting seat(15)Connection, in housing(9)Anterior panel(12)It is provided with single-chip microcomputer(14)Controlling organization and liquid crystal Show device(1).
2. iodate oil heating unit according to claim 1, it is characterized in that:In panel(12)The controlling organization bag of upper setting Include liquid crystal display(1), menu setecting button(2), menu reset key(3), temperature heighten button(4)Button is turned down with temperature (6), the liquid crystal display(1)Provided with two pieces of correspondence heating muff A(10)With heating muff B(11)Temperature display device Mouthful, menu setecting button(2), menu reset key(3), temperature heighten button(4)Button is turned down with temperature(6)It is arranged on liquid crystal Display(1)Surrounding any part.
3. iodate oil heating unit according to claim 2, it is characterized in that:In the liquid crystal display(1)Surrounding appoint Position anticipate provided with power switch(5), power switch(5)Connect the single-chip microcomputer(14).
4. iodate oil heating unit according to claim 2, it is characterized in that:In the liquid crystal display(1)Surrounding appoint Position anticipate provided with warning lamp(7), warning lamp(7)Connect the single-chip microcomputer(14).
5. iodate oil heating unit according to claim 1, it is characterized in that:In temperature sensor(17)Bottom provided with branch Strut(18), the support bar(18)Lower end is fixed on housing(9)On bottom plate.
CN201510177338.9A 2015-04-15 2015-04-15 A kind of iodate oil heating unit Expired - Fee Related CN104791985B (en)

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CN201510177338.9A CN104791985B (en) 2015-04-15 2015-04-15 A kind of iodate oil heating unit

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CN201510177338.9A CN104791985B (en) 2015-04-15 2015-04-15 A kind of iodate oil heating unit

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CN104791985A CN104791985A (en) 2015-07-22
CN104791985B true CN104791985B (en) 2017-10-10

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2248106A (en) * 1990-08-09 1992-03-25 Denley Instr Ltd Warming infusion fluids
CN2559360Y (en) * 2002-08-02 2003-07-09 天津医科大学附属肿瘤医院 Intelligent infusion monitoring instrument
CN101338937A (en) * 2008-01-10 2009-01-07 刘关泰 Quick heating electric water heater letting out hot water according to instruction
CN202010328U (en) * 2011-03-16 2011-10-19 中国人民解放军军事医学科学院附属医院 Temperature-adjustable infusion pump
CN202478327U (en) * 2012-02-29 2012-10-10 中国人民解放军第四五一医院 Medical infusion heater
CN204630006U (en) * 2015-04-15 2015-09-09 中国人民解放军第150中心医院 A kind of iodized oil heater

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2248106A (en) * 1990-08-09 1992-03-25 Denley Instr Ltd Warming infusion fluids
CN2559360Y (en) * 2002-08-02 2003-07-09 天津医科大学附属肿瘤医院 Intelligent infusion monitoring instrument
CN101338937A (en) * 2008-01-10 2009-01-07 刘关泰 Quick heating electric water heater letting out hot water according to instruction
CN202010328U (en) * 2011-03-16 2011-10-19 中国人民解放军军事医学科学院附属医院 Temperature-adjustable infusion pump
CN202478327U (en) * 2012-02-29 2012-10-10 中国人民解放军第四五一医院 Medical infusion heater
CN204630006U (en) * 2015-04-15 2015-09-09 中国人民解放军第150中心医院 A kind of iodized oil heater

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