CN104784577A - Traditional Chinese medicine formula granule for treating chloasma - Google Patents
Traditional Chinese medicine formula granule for treating chloasma Download PDFInfo
- Publication number
- CN104784577A CN104784577A CN201510221730.9A CN201510221730A CN104784577A CN 104784577 A CN104784577 A CN 104784577A CN 201510221730 A CN201510221730 A CN 201510221730A CN 104784577 A CN104784577 A CN 104784577A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- chinese medicine
- traditional chinese
- chloasma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a traditional Chinese medicine formula granule for treating chloasma. The traditional Chinese medicine formula granule for treating the chloasma is characterized in that included active elements are prepared from the following raw materials in parts by weight: rehmannia root, herb of shorthorned epimedium and the like. The traditional Chinese medicine formula granule is prepared by water extraction, and spray drying. The traditional Chinese medicine formula granule has the functions of inhibiting tyrosinase activity, reducing the generation of melanin, slowing skin aging and treating chloasma.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of Traditional Chinese medicine granule being used for the treatment of chloasma and its preparation method and application.
Background technology
Chloasma is because female endocrine dyscrasia, and stress is large, and lacking vitamin and external chemicals in various disease (hepatic and kidney function obstacle, gynaecopathia, diabetes) etc. and body stimulates and cause, and lacks effective Therapeutic Method at present.
Summary of the invention
Goal of the invention: in order to solve the problem, the object of the present invention is to provide a kind of Traditional Chinese medicine granule being used for the treatment of chloasma and its preparation method and application.
Technical scheme: the object of the invention is by following scheme realize:
A kind of Traditional Chinese medicine granule being used for the treatment of chloasma, active component contained by it is prepared from by following raw materials in part by weight proportioning: Radix Rehmanniae 10 parts, the Radix Astragali 80 parts, Herba Epimedii 10 parts, Fructus Corni 10 parts, the Rhizoma Anemarrhenae 10 parts, Radix Morindae Officinalis 10 parts, Radix Bupleuri 15 parts, Radix Paeoniae Rubra 10 parts, Ramulus Cinnamomi 8 parts, Radix Scutellariae 10 parts, Rhizoma Chuanxiong 12 parts, 10 parts, Poria, Cortex Moutan 10 parts, Radix Salviae Miltiorrhizae 14 parts, Rhizoma Cyperi 15 parts, Fructus Gardeniae 10 parts, Radix Achyranthis Bidentatae 10 parts, 10 parts, Radix Glycyrrhizae, Fructus Atriplicis Sibiricae 12 parts, Herba Taxilli 12 parts, the Radix Angelicae Dahuricae 15 parts, Herba Leonuri 10 parts, Rhizoma Curculiginis 12 parts, Semen Coicis 20 parts, use water extraction respectively 2 times, spraying dry, mixing, make Compatible Granule.
The described Traditional Chinese medicine granule being used for the treatment of chloasma, described water extraction 2 times, amount of water is 10 times amount of medical material weight for the first time, decocts 2 hours, second time amount of water is 8 times amount of medical material weight, decocts 1 hour, collecting decoction, concentrated, spraying dry, obtains granule.
The application of the described Traditional Chinese medicine granule being used for the treatment of chloasma in preparation treatment chloasma Traditional Chinese medicine granule.
Beneficial effect:
The present invention treats chloasma, has the effect that obvious check melanin is formed, and energy blood circulation promoting is very effective, Cucumber Extract cell, inhibiting bacteria and diminishing inflammation, heat-clearing and toxic substances removing.The present invention can restraint of tyrosinase active function, and the pigmentation of local is reduced, and repairs skin damaged fibers, activating skin histiocyte, delay skin aging.We are not containing caustic, and drug safety, facilitates, and has good clinical efficacy and DEVELOPMENT PROSPECT.Formulation of the present invention is reasonable, and compatibility is rigorous, through long-term clinical verification, and determined curative effect.The present invention consists of Chinese crude drug, has no side effect, low price.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, in conjunction with detailed description of the invention, the present invention is further described as follows:
Be Maguireothamnus speciosus to the dry herb sitting leaf to sitting leaf in the present invention, Herba Pratiae Nummulariae is the herb that Herba Reineckeae Carneae belongs to Liliaceae Herba Reineckeae Carneae, and all the other are pharmacopeia kind.
Preparation embodiment: above table Raw proportioning is example, comprises the following steps:
Embodiment 1: get Radix Rehmanniae 10g, Radix Astragali 80g, Herba Epimedii 10g, Fructus Corni 10g, Rhizoma Anemarrhenae 10g, Radix Morindae Officinalis 10g, Radix Bupleuri 15g, Radix Paeoniae Rubra 10g, Ramulus Cinnamomi 8g, Radix Scutellariae 10g, Rhizoma Chuanxiong 12g, Poria 10g, Cortex Moutan 10g, Radix Salviae Miltiorrhizae 14g, Rhizoma Cyperi 15g, Fructus Gardeniae 10g, Radix Achyranthis Bidentatae 10g, Radix Glycyrrhizae 10g, Fructus Atriplicis Sibiricae 12g, Herba Taxilli 12g, Radix Angelicae Dahuricae 15g, Herba Leonuri 10g, Rhizoma Curculiginis 12g, Semen Coicis 20g, use water extraction respectively 2 times, amount of water is 10 times amount of medical material weight for the first time, decoct 2 hours, second time amount of water is 8 times amount of medical material weight, decoct 1 hour, collecting decoction, concentrated, spraying dry, obtain granule Traditional Chinese medicine granule.
2. clinical observation material
2.1 sample preparations: prepare clinical trial sample by above-described embodiment 1, specification is 10g/ bag, is 30g/ bag containing crude drug amount.
2.2 physical data: 50 routine patients are in May, 2012 ~ outpatient service in August, 2013 outpatients.With reference to " new Chinese medicine guideline of clinical investigations ", inclusive criteria: the 1. age is between 19 years old-53 years old, women.2. without infection, not irritated to this medicine, be a cup too low abnormal person.Meet the diagnostic criteria (clinical diagnosis of Dermatology Professional Committee of CAIM (Chinese Association Of Integrative Medicine) pigment disease group chloasma and criterion of therapeutical effect (revised draft in 2003)) of chloasma.3. get rid of other dermatosiss and anaphylactic disease:, not allergy sufferers non-stimulated to this medicine.Similar drug person was not used before treatment, and without carrying out other similar drugs experimenter.4. meet the diagnostic criteria of chloasma and the volunteer patients in the know of inclusive criteria; Complete informed consent and relevant announcer.
Exclusion standard: the 1. diagnosis and the inclusive criteria that do not meet chloasma; Do not meet the inclusive criteria of chloasma; 2. there are concurrent infection, psychological problem irritated to this medicine.3. judge to have and reduce into group probability or make, into other complicated medical histories of group, as working environment often changes, easily to cause situation lost to follow-up according to researcher; Or participating in the experimenter of other drug clinical research.
2.3 Therapeutic Method
The treatment of patient with chloasma: soakedly to take, every day 3 bags, treatments period stops using other with special efficacy skin care item and medicine, within one month, is a course for the treatment of.
2.4 observation of curative effect criterions of therapeutical effect are with reference to " new Chinese medicine guideline of clinical investigations ".Basic healing: 1. naked eyes disappear depending on mottle area and are greater than 90%, and color disappears substantially, and 1 meter apart from invisible obvious speckle.2. decline after point system calculating treatment index >=0.8.Effective: 1. naked eyes disappear depending on mottle area and are greater than 60%, and color is obviously thin out.2. decline after point system calculating treatment index >=0.5.Take a turn for the better: 1. naked eyes disappear depending on mottle area and are greater than 30%, and color is thin out.2. decline after point system calculating treatment index >=0.3.Invalid: 1. naked eyes disappear depending on mottle area and are less than 30%, color change is not obvious.2. decline after point system calculating treatment index >=0.
Computing formula (nimodipine method): [before (before treatment the rear integration of integration-treatment)/treatment integration] × 100%.
2.5 therapeutic outcomes:
Check immediately after 50 examples all terminate 1 course for the treatment of.Result: cure 16 examples, effective 18 examples, effective 9 examples, invalid 7 examples, total effective rate 86%.
Claims (3)
1. one kind is used for the treatment of the Traditional Chinese medicine granule of chloasma, it is characterized in that the active component contained by it is prepared from by following raw materials in part by weight proportioning: Radix Rehmanniae 10 parts, the Radix Astragali 80 parts, Herba Epimedii 10 parts, Fructus Corni 10 parts, the Rhizoma Anemarrhenae 10 parts, Radix Morindae Officinalis 10 parts, Radix Bupleuri 15 parts, Radix Paeoniae Rubra 10 parts, Ramulus Cinnamomi 8 parts, Radix Scutellariae 10 parts, Rhizoma Chuanxiong 12 parts, 10 parts, Poria, Cortex Moutan 10 parts, Radix Salviae Miltiorrhizae 14 parts, Rhizoma Cyperi 15 parts, Fructus Gardeniae 10 parts, Radix Achyranthis Bidentatae 10 parts, 10 parts, Radix Glycyrrhizae, Fructus Atriplicis Sibiricae 12 parts, Herba Taxilli 12 parts, the Radix Angelicae Dahuricae 15 parts, Herba Leonuri 10 parts, Rhizoma Curculiginis 12 parts, Semen Coicis 20 parts, use water extraction respectively 2 times, spraying dry, mixing, make Compatible Granule.
2. be used for the treatment of the Traditional Chinese medicine granule of chloasma as claimed in claim 1, it is characterized in that described water extraction 2 times, amount of water is 10 times amount of medical material weight for the first time, decoct 2 hours, second time amount of water is 8 times amount of medical material weight, decocts 1 hour, collecting decoction, concentrated, spraying dry, obtains granule.
3. be used for the treatment of the application of Traditional Chinese medicine granule in treatment chloasma Traditional Chinese medicine granule of chloasma as claimed in claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510221730.9A CN104784577A (en) | 2015-05-05 | 2015-05-05 | Traditional Chinese medicine formula granule for treating chloasma |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510221730.9A CN104784577A (en) | 2015-05-05 | 2015-05-05 | Traditional Chinese medicine formula granule for treating chloasma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104784577A true CN104784577A (en) | 2015-07-22 |
Family
ID=53550063
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510221730.9A Withdrawn CN104784577A (en) | 2015-05-05 | 2015-05-05 | Traditional Chinese medicine formula granule for treating chloasma |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104784577A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102335342A (en) * | 2011-10-10 | 2012-02-01 | 南京中医药大学 | Chinese medicinal composition for treating chloasma, preparation method and application thereof |
| CN104173607A (en) * | 2013-05-28 | 2014-12-03 | 北京中医药大学 | Pharmaceutical composition for treating chloasma and preparation method thereof |
-
2015
- 2015-05-05 CN CN201510221730.9A patent/CN104784577A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102335342A (en) * | 2011-10-10 | 2012-02-01 | 南京中医药大学 | Chinese medicinal composition for treating chloasma, preparation method and application thereof |
| CN104173607A (en) * | 2013-05-28 | 2014-12-03 | 北京中医药大学 | Pharmaceutical composition for treating chloasma and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100421723C (en) | Hair quickly regenerating liquid | |
| CN103272188A (en) | Agent for curing sequelae of apoplexy | |
| CN103768385A (en) | Medicinal liquor capable of maintaining beauty and keeping young and preparation method thereof | |
| CN107095828B (en) | Daily chemical product composition with skin barrier repair function and preparation method and application thereof | |
| CN103385986B (en) | Chinese medicine tincture for treating leucoderma | |
| CN101947293A (en) | Medicament for treating urinary tract infection and preparation method thereof | |
| CN103212021A (en) | Traditional Chinese medicine composition used for treating chloasma | |
| CN101732631B (en) | Traditional Chinese medicine composite mask for dispelling acnes | |
| CN1320895C (en) | Rhinitis treating Chinese medicine prepn | |
| CN101926857A (en) | Traditional Chinese medicinal liniment for treating vitiligo | |
| CN102078559A (en) | Chinese medicinal composition with functions of tonifying kidney and strengthening brain | |
| CN103405635A (en) | Traditional Chinese medicine composition for treating middle and old aged constipation | |
| CN104644857A (en) | Traditional Chinese medicine formula for treating acnes | |
| CN102961647A (en) | Traditional Chinese medicine for treating osteoporosis | |
| CN103893601B (en) | A kind of medicament for the treatment of mumps | |
| CN104784577A (en) | Traditional Chinese medicine formula granule for treating chloasma | |
| CN103566219A (en) | Traditional Chinese medicine composition for treating cold | |
| CN102671042A (en) | Traditional Chinese medicinal composition for treating acne and preparation method thereof | |
| CN103736011B (en) | Injection care drug of a kind of cholesterol reducing and preparation method thereof | |
| CN102908508B (en) | Medicinal composition for treating seborrheic alopecia and preparation method thereof | |
| CN101530479B (en) | Traditional Chinese medicine for treating diabetes mellitus and muscle atrophy | |
| CN104997988A (en) | Traditional Chinese medicine composite for treating leucoderma | |
| CN103381240A (en) | Wind-dispelling coolant and application of same in drug for treating contact dermatitis | |
| CN104800599A (en) | Traditional Chinese medicinal composition for treating deficiency of kidney-yin | |
| CN103566044A (en) | Traditional Chinese medicinal composition for activating blood circulation to relieve pain |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| EXSB | Decision made by sipo to initiate substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20150722 |
|
| WW01 | Invention patent application withdrawn after publication |