CN104782514B - A kind of biological experiment platform for simulating earth magnetism outburst - Google Patents

A kind of biological experiment platform for simulating earth magnetism outburst Download PDF

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Publication number
CN104782514B
CN104782514B CN201510164196.2A CN201510164196A CN104782514B CN 104782514 B CN104782514 B CN 104782514B CN 201510164196 A CN201510164196 A CN 201510164196A CN 104782514 B CN104782514 B CN 104782514B
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metallic shield
cage
shield cage
signal generator
earth magnetism
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CN104782514A (en
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李雪松
吴晖
董亮
杨龙
张寰波
邓杨林
耿华
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First Affiliated Hospital of Kunming Medical University
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First Affiliated Hospital of Kunming Medical University
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Abstract

The invention discloses a kind of biological experiment platform for simulating earth magnetism outburst, it includes main control computer, signal generator, metallic shield cage, radiating antenna;Main control computer is connected by transmission cable with signal generator, signal generator is connected by signal cable with metallic shield cage, the radiating antenna of more than one is arranged in metallic shield cage, radiating antenna placement direction is consistent with earth magnetism field direction, metallic shield cage is metal grill cube cage, and mesh size is 0.25 4cm thereon2, metallic shield cage top is provided with door;Apparatus of the present invention can accurately simulate earth's magnetic field electromagnetic wave activity, the change procedure of true reappearance electromagnetic wave, can observe the change of the experimental animal physical signs in metallic shield cage, study geomagnetic activity in Space weather event and induce health event;The platform is an emulation platform, and research on the platform can remove the more uncertainty in clinical human's observation from, is advantageous to most direct scientific research data and obtains.

Description

A kind of biological experiment platform for simulating earth magnetism outburst
Technical field
The present invention relates to a kind of biological experiment platform for simulating earth magnetism outburst, suitable for bioelectromagnetics radiation research and space Weather-geomagnetic activity-health event experimental field, the environment broken out especially suitable for earth magnetism in simulation Space weather event State, and then study its influence to life entity.
Background technology
Various natural physical fields there is from being born from the earth, and life lives in various physical fields from after being born (Gravitation, electricity, magnetic etc.)Sphere of action in, the change of physical environment in biosphere plays the potential material impact of human health.
Human magnetic field is to produce, maintain under this overall background of magnetic field of the earth.It there will necessarily be between this 2 magnetic fields Interaction.Tellurian life was born in the remote Paleozoic Era, at that time on the earth there is very powerful geomagnetism energy, The energy exists with about 10Hz SLF electromagnetic waveshape, because the energy of this electromagnetic wave is original organic molecule collection In get up just to result in the birth of life:Protein is exactly a typical case.Therefore, these resulting chemical substance tectosomes Ultralow frequency ripple all with about 10Hz produces resonance, and life caused by evolution also all shows super to this on this basis The reaction of low frequency wave.
The earth and ionosphere may be constructed a resonant cavity, a special resonant frequency be present in cavity, this frequency Rate is mainly determined by the size of the earth, and the ultra-low frequency electromagnetic wave of this " driving source of life " is excited by the lightning discharge in the whole world Preservation is continued up as wave band intrinsic in earth's magnetic field so far, and nineteen fifty-two Schumann (Schumann) is found that depositing for the phenomenon It is being referred to as " schumann resonance (Schumann Resonance) " one and is sharing five crests of A, B, C, D, E, wherein fundamental frequency exists 7.8Hz or so, remaining crest exist respectively:14、20、26、33Hz(Fig. 3).
Afterwards, reed open country doctor of Kyoto Univ Japan has found that this 5 peaking modes of " schumann resonance " enter just and human brain Frequency of brain wave coincide.E.E.G can be divided into according to frequency:δ ripples, θ ripples, α ripples, the ripples of β 1 and the ripples of β 2.The two resonate marvellous It coincide and demonstrates --- uniformity be present in the intrinsic fluctuation of the earth and the fluctuation of life!But this discovery simultaneously is on the other hand It is bright:If there occurs, there occurs exception, potentially will be brought not to life entity with earth's magnetic field electromagnetic wave for the environment residing for life entity Good influence.
Violent solar burst and CME(Coronal Mass Ejections, CME)It is pace weather weather Driving source, and directly affect near earth space environment and change most important factor.And ground void relation-solar activity-space day Gas change is to induce the principal element of Geophysical background especially earth's magnetic field-Ionospheric variability.
Notice the Space weather event of solar activity induction to people external scientific circles since the sixties in last century The health of class may have potential impact, and it, which is represented, has Friedman et al. in, nineteen sixty-five and B.J. Lipa et al. in 1963 In 1976《Nature》Upper plurality of articles, by compare in Space weather event the typical earth magnetism Breakout events same day, Then heart and brain obstruct, accept situation of change of the number relative to the earth magnetism pediocratic mental disorder hospital day for medical treatment in several days, find that The per day rate of accepting for medical treatment of above-mentioned disease has obvious rising compared to the earth magnetism pediocratic during geomagnetic activity.
That waits cardiovascular event caused by starting the external change to space weather thenceforth has carried out years of researches: In terms of finding that affected health index is mainly reflected in cardiovascular event.
E. Stoupel J. et al. have studied solar proton number flow, 2800MHz wave band flows in 1995-1997 Relation between heart infarction, cerebral apoplexy, draw the positive correlation highest of 2800MHz solar radio radiations changes in flow rate and angiocardiopathy (0.56, P<0.001) ;S. Dimitrova et al. with 2009 by monitor 86 healthy volunteers on the day of geomagnetic activity And the blood pressure in front and rear three days, it was therefore concluded that:Extremely strong geomagnetic activity the previous day human body diastolic pressure and systolic pressure have substantially Change, bring hidden danger for angiocardiopathy;Ch. Katsavriasp in 2010 et al. have found:The urgency that ST and NST sections are raised Property coronary syndrome the moon incidence of disease with CME and solar flare(flare)There is very strong positive correlation to reach as high as(0.84, p <0.001).
Other research also confirm that, when solar activity cause earth magnetism significant change when, human normal biological rhythm i.e. by Influence, body will produce stress reaction to adapt to new environment.Meanwhile cardiovascular index of correlation will change, such as blood Pressure raises, increased heart rate, and arrhythmia cordis, the incidence of disease of heart failure increase etc., and the hypothesis is confirmed by external zoopery.
Also there are a small amount of related science achievement in research, nineteen ninety-five Zeng Zhiquan et al. in the country by comparing solar activity many indexes Parameter, including 2800MHz solar activity flows, solar flare number, are closed between relative sunspot number and coronary heart disease, cerebral apoplexy System, wherein 2800MHz solar radio radiations changes in flow rate and the positive correlation highest of two kinds of disease incidences(The degree of correlation reaches 0.618 With 0.591).
Juraj Gmitrov et al. tested with the irradiation that dynamic and static two kinds of electromagnetic fields have been carried out to rabbit in 2007, wherein dynamic Geomagnetic storm environment has been imitated in the alternating magnetic field experiment of state completely, and their experimental result is confirmed under geomagnetic storm environment, experimental rabbit Microcirculation and the phenomenon that reduces of arterial pressure reflex sensitivity, this is the main omen table that cardiovascular event occurs It is existing.For this some have speculated that:The change in earth's magnetic field drives the change of organism interior magnetic field, have impact on animal body in-laws' hydrophobic grouping Interaction, change the degree of ionization of metal ion, make free OH- and H2O2Ratio change, make neuroendocrine system by Influence, blood pressure heart rate changes, and the viscosity and coagulability of blood are affected, and causes a series of diseases including angiocardiopathy Occur, development.Relation from the point of view of current data analysis between solar activity-geomagnetic activity-health is as shown in Figure 2;
Sun aggravating activities and CME (Coronal Mass Ejection, CME) phenomenon are to cause ground magnetic variation Change direct factor, study the relation of this factor and health, especially study its influence to cardiovascular disease incidence:Face Bed and lapses to feature, provides foundation with diagnoses and treatment for health forecast, has become a key subjects of global common concern, There is important Practical significance to the national economic development, national security and human lives.
There are two major issue pendulum for this in face of us:1st, how level during GEOMAGNETIC CHANGE in human body changes, and is It is no to observe the change of corresponding animal indicators in vivo extremely in earth's magnetic field by simulating2nd, effective early warning hand how is taken Section prevents the generation of this event
The method that mainly uses in the world is at present:The Forbush Decrease observation early warning of universe linear flow rate.The good fortune of ultra rays Bush declines(Cosmic ray Forbush Decrease, abbreviation FD)A kind of typical thing in phenomenal space weather events Part, it be due in solar activity huge solar flare by CME into nearly solar-terrestrial physics, ultra rays are generated and blocked And the universe linear flow rate observed declines, the change by monitoring ultra rays can know that solar-terrestrial physics plasma density becomes Change, and then speculate geomagnetic activity time of origin.
For this, Dorman, L.I et al. obtains earth magnetism by observing the variation relation between FD phenomenon and cardiovascular event Field change moment and heart infarction, Cerebral Haemorrhage Invasion Rate rise time sequencing:Generally FD phenomenons betide heart and brain stalk thing Before part in 15-20 hours, this just provides theoretical foundation for such event using the early warning of FD phenomenons.
The content of the invention
Present invention aims at a kind of biological experiment platform for simulating earth magnetism outburst is provided, it includes main control computer, letter Number generator, metallic shield cage, radiating antenna;Main control computer is connected by transmission cable with signal generator, and signal occurs Device is connected by signal cable with metallic shield cage, and more than one radiating antenna is arranged in metallic shield cage, and radiating antenna is put It is consistent with earth magnetism field direction to put direction;
Wherein described metallic shield cage is metal grill cube cage, and mesh size is 0.25-4cm thereon2, metallic shield Cage top end is provided with door, for placing experimental animal and access for radiating antenna.
The signal generator can be produced 50Hz and its following arbitrary signal spectral combination by main control computer control, special It is not to simulate electromagnetic radiation situation when Schumann ripple situation and earth magnetism break out in space.
The radiating antenna is Helmholtz antenna.
The electromagnetic radiation situation when being broken out on the biological experiment platform of present invention simulation earth magnetism outburst by simulating earth magnetism, prison The change of the various physiological characteristics of experimental animal rat in metallic shield cage is surveyed, so as to provide between geomagnetic activity and health Correlation, on being possible to bring health the magnetic field of influence to provide effective early warning extremely.
Apparatus of the present invention pass through signal source(Signal generator)The rat electromagnetic radiation of+radiating antenna into metallic shield cage Ripple, radiation signal frequency spectrum and its strength structure are as follows:
According to Balser, the situation for the Schumann ripple that Wagner and K nig record in nineteen sixty, strong equal of its primary electrical Root value is:0.6 mV/m-1mV/m., scope about about exist in 0.22-1.12 mV/m, power bracket:0.013-0.33 pW/cm2
The generation that module occurs containing C-RIO programmable signals that signal generator is produced using NI companies in the present invention Device, builds five major frequency components of Schumann resonance in a program, and the adjustment of program is controlled by main control computer;In order to avoid The interference that earth's magnetic field and other electromagnetic fields are brought, apparatus of the present invention using when whole system be placed in micro-wave screening room, and Antenna direction is that north-south is consistent with earth's magnetic field, and signal noise is about 10000nT-50000nT.
The advantages of apparatus of the present invention and technique effect:The platform has the advantages of simple in construction, easy to operate, present invention dress Earth's magnetic field electromagnetic wave activity can accurately be simulated by putting, and the change procedure of true reappearance electromagnetic wave, can observe the reality in screening cage The change of animal rat physical signs is tested, geomagnetic activity in Space weather event is studied and induces health event;The platform is One emulation platform, research on the platform can remove the more uncertainty in clinical human's observation from, be advantageous to most direct Scientific research data obtain.
Brief description of the drawings
Fig. 1 is apparatus of the present invention structural representation;
Graphs of a relation of the Fig. 2 between solar activity-magnetic field of the earth-health of the present invention;
Fig. 3 is the typical Schumann wave frequency spectrogram of the present invention;
In figure:1- metallic shield cages;2- radiating antennas;3- signal generators;4- main control computers;5 be door.
Embodiment
The present invention is described in further detail below by drawings and examples, but the scope of the present invention is not limited to The content.
Embodiment 1:As shown in figure 1, the biological experiment platform of this simulation earth magnetism outburst includes main control computer 4, signal is sent out Raw device 3, metallic shield cage 1, radiating antenna 2;Main control computer 4 is connected by transmission cable with signal generator 3, and signal occurs Device 3 is connected by signal cable with metallic shield cage 1, and radiating antenna 2 is arranged in metallic shield cage 1, radiating antenna placement side To consistent with earth magnetism field direction;Metallic shield cage is metal grill cube cage, and mesh size is 0.25cm thereon2, metal screen Cover cage top end and be provided with door 5, for placing experimental mouse and access for radiating antenna, metallic shield cage size is 150cm × 150 cm×90 cm;
Wherein signal generator can be produced 50Hz and its following arbitrary signal spectral combination by main control computer control, special It is not to simulate electromagnetic radiation situation when Schumann ripple situation and earth magnetism break out in space;The root-mean-square value of signal generator electric-field strength For 0.22-1.12 mV/m, power is 0.013-0.33 pW/cm2, while ensure the signal in whole test system screening cage Noise is 10000nT-50000nT.
Because signal may be programmed, the affected situation of Schumann resonance in geomagnetic storm is simulated in main control computer, mainly Method is:The power of each frequency content is adjusted according to programming, whether there is, the parameter such as deviate, while with field intensity meter measurement calibration, is made Meet earth's magnetic field it is quiet and outburst situation, with specific reference to table 1.
The geomagnetic activity different index table of comparisons of table 1
We choose rat as experimental subjects in zoopery, enter group and packet standard is:
1st, 5-7 month male rats, body weight is at 180-250 grams or so;After adaptability is fed one week, feeding high lipid food (is used 4% cholesterol, 10% lard, 5% white sugar, 0.5% sodium taurocholate, 0.2% propylthiouracil and 80.3% basal feed) raise 12 weeks and build Vertical coronary atherosclerosis model, the myocardium coronary branches of rat are selected after 12 weeks at random in light microscopic or electric Microscopic observation, to produce Patch is the standard for evaluating whether to have formulation coronary syndrome;
2nd, it is divided into two groups:Analog magnetic field irradiation group and open space control group, every group of 30 rats;
3rd, analog magnetic field irradiation group:Rat is put into the metallic shield cage 1 in biological experiment platform of the present invention, adjustment letter Number output amplitude of generator 3, it is divided into quiet, outburst, by force three levels of outburst, is calibrated with field intensity meter;Continuous irradiation 0.1 day, 1 My god, 2 days, 3 days, after one week test rat items physical signs, including:Platelet activation rate, prothrombin time, international standard Change ratio, activated partial thromboplastin time, fibrinogen, plasma viscosity, WBV:Undercut, WBV:Height cuts, The item index such as erythrocyte sedimentation rate, erythrocyte aggregation, packed cell volume.
4th, for open space control rats, the physical signs of rat is acquired when earth magnetism is quiet, including: Platelet activation rate, prothrombin time, INR, activated partial thromboplastin time, fibrinogen, blood plasma Viscosity, WBV:Undercut, WBV:The item indexs such as height is cut, erythrocyte sedimentation rate, erythrocyte aggregation, packed cell volume;
5th, coronary branches observation atheromatous plaque situation of the rat during the earth magnetism pediocratic is simulated is taken, measurement of comparison emulates not With the patch of earth magnetism detonator signal radiation experiments group rat, patch stable case is analyzed.
Contrast under above-mentioned different radiation conditions, the change of every physical signs.
Without geomagnetic activity period compared to the rat in open space, the rat of analog magnetic field irradiation group, fibrin ferment Former time and activated partial thromboplastin time will be reduced, and remaining index such as platelet activation rate, fibrinogen, blood plasma glue Degree, WBV:Undercut, WBV:Height is cut, erythrocyte sedimentation rate, erythrocyte aggregation, packed cell volume etc. will substantially rise.

Claims (3)

  1. A kind of 1. biological experiment platform for simulating earth magnetism outburst, it is characterised in that:Including main control computer, signal generator, gold Belong to screening cage, radiating antenna;Main control computer is connected by transmission cable with signal generator, and signal generator passes through signal electricity Cable is connected with metallic shield cage, and the radiating antenna of more than one is arranged in metallic shield cage, radiating antenna placement direction and ground Magnetic direction is consistent;
    The metallic shield cage is metal grill cube cage, and mesh size is 0.25-4cm thereon2, metallic shield cage top is opened There is door;
    The signal generator is controlled by main control computer and produces 50Hz and its signals below spectral combination.
  2. 2. the biological experiment platform of simulation earth magnetism outburst according to claim 1, it is characterised in that:Signal generator electric field Strong root-mean-square value is 0.22-1.12 mV/m, and power is 0.013-0.33 pW/cm2
  3. 3. the biological experiment platform of simulation earth magnetism outburst according to claim 2, it is characterised in that:In metallic shield cage Signal noise is 10000nT-50000nT.
CN201510164196.2A 2015-04-09 2015-04-09 A kind of biological experiment platform for simulating earth magnetism outburst Expired - Fee Related CN104782514B (en)

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