CN104782514A - Biological experiment platform capable of simulating geomagnetic outbreak - Google Patents
Biological experiment platform capable of simulating geomagnetic outbreak Download PDFInfo
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- CN104782514A CN104782514A CN201510164196.2A CN201510164196A CN104782514A CN 104782514 A CN104782514 A CN 104782514A CN 201510164196 A CN201510164196 A CN 201510164196A CN 104782514 A CN104782514 A CN 104782514A
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Abstract
The invention discloses a biological experiment platform capable of simulating a geomagnetic outbreak. The biological experiment platform capable of simulating the geomagnetic outbreak comprises a main control computer, a signal generator, a metal shielding cage and one or more radiating antennae; the main control computer is connected with the signal generator through a transmission cable, the signal generator is connected with the metal shielding cage through a signal cable, the radiating antennae are arranged in the metal shielding cage, the placing direction of the radiating antennae is in accordance with the earth magnetic field direction, the metal shielding cage is a metal grid cube cage, the size of each mesh opening is 0.25-4 cm<2>, and the upper portion of the metal shielding cage is provided with a door. According to the biological experiment platform capable of simulating the geomagnetic outbreak, the electromagnetic wave activity of an earth magnetic field can be precisely simulated, the changing process of an electromagnetic wave can reappear truly, the physiological index change of an experimental animal in the metal shielding cage can be observed, and a human body health event induced by the geomagnetic activity in a space weather event can be researched; the platform is a simulation platform, more uncertainty in clinical human body observation can be excused by performing the research on the platform, and the acquisition of most direct scientific research data is facilitated.
Description
Technical field
The present invention relates to a kind of biological experiment platform of simulating earth magnetism outburst, be applicable to bioelectromagnetics radiation research and space weather-geomagnetic activity-health event experiment field, be specially adapted to the ambient condition of the outburst of earth magnetism in virtual space weather events, and then study its impact on life entity.
Background technology
Various natural physical field just exists from the earth is born, and namely life lived in the sphere of action of various physical field (gravitation, electricity, magnetic etc.) after being born, and the physical environment change in biosphere plays the potential material impact of human health.
Human magnetic field produces under this overall background of magnetic field of the earth, maintenance.Interaction must be there is between these 2 magnetic fields.Tellurian life was born in the remote Paleozoic Era, at that time the earth also existed very powerful geomagnetism energy, this energy exists with the SLF electromagnetic waveshape of about 10Hz, because this electromagnetic energy puts together original organic molecule the birth that just result in life: protein is exactly a typical case.Therefore, these consequent chemical substance tectosomes all produce with the ultralow frequency ripple of about 10Hz and resonate, and the life of generation of evolving on this basis also all shows the reaction to this ultralow frequency ripple.
The earth and ionosphere can form a resonant cavity, the resonant frequency that in cavity, existence one is special, this frequency determines primarily of the size of the earth, and excite the ultra-low frequency electromagnetic wave of this " driving source of life " to continue preservation so far as wave band intrinsic in earth's magnetic field by the lightning discharge in the whole world always, nineteen fifty-two Schumann (Schumann) has found the existence of this phenomenon, be called that " schumann resonance (Schumann Resonance) " one has A, B, C, D, E five crests, wherein fundamental frequency is at about 7.8Hz, remaining crest exists respectively: 14, 20, 26, 33Hz(Fig. 3).
Afterwards, reed of Kyoto Univ Japan wild doctor find, these 5 peaking mode of " schumann resonance " just enter and coincide with the frequency of brain wave of human brain.E.E.G can be divided into according to frequency: δ ripple, θ ripple, α ripple, β 1 ripple and β 2 ripple.Marvellous the coincideing of these two resonance demonstrates---and there is uniformity in the fluctuation of the fluctuation that the earth is intrinsic and life! But this discovery simultaneously illustrates from another point of view: if the environment residing for life entity there occurs there occurs exception with earth's magnetic field electromagnetic wave, will bring bad impact potentially to life entity.
Violent solar burst and CME(Coronal Mass Ejections, CME) be the drive source of pace weather weather, be also directly affect near earth space environment to change most important factor.And ground void relation-solar activity-space weather change is the principal element of bringing out Geophysical background especially earth's magnetic field-Ionospheric variability.
From the sixties in last century, external scientific circles start to notice that the Space weather event that solar activity is brought out may have potential impact to the health of the mankind, its representative had the people such as Friedman in 1963, the people such as nineteen sixty-five and B.J. Lipa in 1976 at " Nature " upper many sections of articles, by comparison typical earth magnetism Breakout events same day in Space weather event, heart and brain stalk in several days subsequently, accept the situation of change of number relative to the earth magnetism pediocratic mental disorder hospital day for medical treatment, just to find that during geomagnetic activity the per day rate of accepting for medical treatment of above-mentioned disease compares to the earth magnetism pediocratic and has obvious rising.
Wait thenceforth start abroad change to space weather the cardiovascular event caused carried out years of researches: concentrate now the affected health index of discovery to be mainly reflected in cardiovascular event aspect.
E. the people such as Stoupel J. have studied that solar proton number flow, 2800MHz wave band flow and the heart obstruct in 1995-1997, relation between cerebral apoplexy, draw the positive correlation of 2800MHz solar radio radiation changes in flow rate and angiocardiopathy the highest (0.56, P<0.001); S. the people such as Dimitrova and 2009 are by the blood pressure of monitoring 86 healthy volunteers within the geomagnetic activity same day and front and back three days, reach a conclusion: magnetic acitvity human body the previous day diastolic pressure and systolic pressure have obvious change strongly, for angiocardiopathy brings hidden danger; The people such as Ch. Katsavriasp in 2010 find: the moon incidence of disease of the acute coronary syndrome that ST and NST section is raised all has very strong positive correlation to reach as high as (0.84, p<0.001) with CME and solar flare (flare).
Other research also confirms, when solar activity causes earth magnetism significant change, namely human normal biorhythm is affected, and body will produce stress reaction to adapt to new environment.Meanwhile, cardiovascular index of correlation will change, as blood pressure raise, increased heart rate, the incidence of disease increase etc. of arrhythmia cordis, heart failure, this hypothesis confirm by external zoopery.
Domestic also have a small amount of related science achievement in research, the people such as nineteen ninety-five Zeng Zhiquan are by comparison solar activity many indexes parameter, comprise 2800MHz solar activity flow, solar flare number, relation, the wherein positive correlation of 2800MHz solar radio radiation changes in flow rate and two kinds of disease incidences the highest (degree of correlation reaches 0.618 and 0.591) between relative sunspot number and coronary heart disease, cerebral apoplexy.
The people such as Juraj Gmitrov and 2007 are tested the irradiation that rabbit has carried out dynamic and static two kinds of electromagnetic fields, wherein geomagnetic storm environment has been imitated in dynamic alternating magnetic field experiment completely, their experimental result confirms under geomagnetic storm environment, all there is the phenomenon reduced in the microcirculation of experimental rabbit and arterial pressure reflex sensitivity, this is the main omen performance that cardiovascular event occurs.Someone infers for this reason: the change in earth's magnetic field drives the change of organism interior magnetic field, have impact on the interaction of animal body in-laws hydrophobic grouping, changes the degree of ionization of metal ion, makes free OH-and H
2o
2ratio change, make neuroendocrine system influenced, blood pressure heart rate changes, and viscosity and the coagulability of blood are affected, and causes angiocardiopathy in the generation of interior a series of diseases, development.From the relation between current data analysis solar activity-geomagnetic activity-health as shown in Figure 2;
Sun aggravating activities and CME (Coronal Mass Ejection, CME) phenomenon causes GEOMAGNETIC CHANGE direct factor, study the relation of this factor and health, especially its impact on cardiovascular disease incidence is studied: Clinical symptoms and lapsing to, for health forecast and diagnoses and treatment provide foundation, become the common key subjects be concerned about in the whole world, to the national economic development, national security and human lives, there is important Practical significance.
There are two major issue pendulum in face of us: how the level 1, during GEOMAGNETIC CHANGE in human body changes for this reason, can by simulation abnormal change observing corresponding animal indicators in vivo in earth's magnetic field? 2, how to take effective early warning means to prevent the generation of this event?
The main way adopted is in the world at present: the Forbush Decrease observation early warning of ultra rays flow.Forbush Decrease (the cosmic ray Forbush Decrease of ultra rays, be called for short FD) a kind of typical event in phenomenal space weather events, it be due to solar flare huge in solar activity by CME in nearly solar-terrestrial physics, ultra rays are created and to block and the ultra rays flow that observes declines, plasma density change in solar-terrestrial physics can be known by monitoring the change of ultra rays, and then magnetic acitvity time of origin speculatively.
Dorman for this reason, the people such as L.I obtain the geomagnetic field variation moment by the variation relation observed between FD phenomenon and cardiovascular event and the heart obstructs, Cerebral Haemorrhage Invasion Rate rise time sequencing: generally FD phenomenon betides before heart and brain stalk event in 15-20 hour, this is just for adopting such event of FD phenomenon early warning to provide theoretical foundation.
Summary of the invention
The object of the invention is to provide a kind of biological experiment platform of simulating earth magnetism outburst, and it comprises main control computer, signal generator, metallic shield cage, radiating antenna; Main control computer is connected with signal generator by transmission cable, and signal generator is connected with metallic shield cage by signal cable, and more than one radiating antenna is arranged in metallic shield cage, and radiating antenna placement direction is consistent with direction, earth's magnetic field;
Wherein said metallic shield cage is metal grill cube cage, and its online hole size is 0.25-4cm
2, metallic shield cage top has door, for placing laboratory animal and the access for radiating antenna.
Electromagnetic radiation situation when described signal generator controls to produce Schumann ripple situation and earth magnetism outburst in 50Hz and following arbitrary signal spectral combination, particularly virtual space by main control computer.
Described radiating antenna is Helmholtz antenna.
By electromagnetic radiation situation during the outburst of simulation earth magnetism on the biological experiment platform that the present invention simulates earth magnetism outburst, the change of monitoring various physiological characteristic of experimental animal rat in metallic shield cage, thus the correlation provided between geomagnetic activity and health, on likely bringing health, the magnetic field of impact is abnormal provides effective early warning.
Apparatus of the present invention by signal source (signal generator)+radiating antenna to the rat radiated electromagnetic wave in metallic shield cage, radiation signal frequency spectrum and strength structure as follows:
The situation of the Schumann ripple recorded in nineteen sixty according to Balser, Wagner and K nig, the root-mean-square value that its primary electrical is strong is: 0.6 mV/m-1mV/m., and scope is greatly about 0.22-1.12 mV/m, and power bracket is greatly about 0.013-0.33 pW/cm
2.
The generator containing C-RIO programmable signal generation module that in the present invention, signal generator adopts NI company to produce, build five major frequency components of Schumann resonance in a program, the adjustment of program is controlled by main control computer; In order to avoid the interference that earth's magnetic field and other electromagnetic fields bring, when apparatus of the present invention use, whole system is all positioned over micro-wave screening indoor, and antenna direction is that north-south is consistent with earth's magnetic field, and signal noise is approximately 10000nT-50000nT.
The advantage of apparatus of the present invention and technique effect: this platform has simple, the easy to operate advantage of structure, apparatus of the present invention can accurate analog earth's magnetic field electromagnetic wave movable, the electromagnetic change procedure of true reappearance, can observe the change of the experimental animal rat physical signs in screening cage, in research Space weather event, geomagnetic activity brings out health event; This platform is an emulation platform, and research on the platform can remove the more uncertainty in clinical human's observation from, is conducive to the most direct scientific research data acquisition.
Accompanying drawing explanation
Fig. 1 is apparatus of the present invention structural representation;
Fig. 2 is the graph of a relation between solar activity-magnetic field of the earth-health of the present invention;
Fig. 3 is the present invention's typical Schumann ripple spectrogram;
In figure: 1-metallic shield cage; 2-radiating antenna; 3-signal generator; 4-main control computer; 5 is door.
Embodiment
Below by drawings and Examples, the present invention is described in further detail, but scope is not limited to described content.
Embodiment 1: as shown in Figure 1, the biological experiment platform of this simulation earth magnetism outburst comprises main control computer 4, signal generator 3, metallic shield cage 1, radiating antenna 2; Main control computer 4 is connected with signal generator 3 by transmission cable, and signal generator 3 is connected with metallic shield cage 1 by signal cable, and radiating antenna 2 is arranged in metallic shield cage 1, and radiating antenna placement direction is consistent with direction, earth's magnetic field; Metallic shield cage is metal grill cube cage, and its online hole size is 0.25cm
2, metallic shield cage top has door 5, and for placing experimental mouse and the access for radiating antenna, metallic shield cage is of a size of cm × 90,150cm × 150 cm;
Electromagnetic radiation situation when wherein signal generator controls to produce Schumann ripple situation and earth magnetism outburst in 50Hz and following arbitrary signal spectral combination, particularly virtual space by main control computer; The root-mean-square value of signal generator electric-field strength is 0.22-1.12 mV/m, and power is 0.013-0.33 pW/cm
2, guarantee that the signal noise in whole test macro screening cage is 10000nT-50000nT simultaneously.
Because signal is able to programme, the affected situation of Schumann resonance in magnetic storm in analog in main control computer, main method is: according to the power of each frequency content of programming adjustment, with or without, the parameter such as to depart from, measure calibration with field intensity meter simultaneously, make it the situation that coincidently magnetic field is quiet and break out, concrete reference table 1.
The table 1 geomagnetic activity different index table of comparisons
。
In zoopery, we choose rat as experimental subjects, enter group and grouping standard is:
1,5-7 month male rat, body weight is at about 180-250 gram; After adaptability feeds one week, feeding high lipid food (with 4% cholesterol, 10% lard, 5% white sugar, 0.5% sodium taurocholate, 0.2% propylthiouracil and 80.3% basal feed) is raised and is set up coronary atherosclerosis model in 12 weeks, the myocardium coronary branches of rat is selected at random at light microscopic or electric Microscopic observation, to produce patch for evaluating the standard whether with formulation coronary syndrome after 12 weeks;
2, be divided into two groups: analog magnetic field irradiation group and open space control group, often organize 30 rats;
3, analog magnetic field irradiation group: the metallic shield cage 1 rat being put into biological experiment platform of the present invention, adjustment signal generator 3 output amplitude, is divided into quiet, outburst, by force outburst three levels, calibrates with field intensity meter; The every physical signs of test rat after Continuous irradiation 0.1 day, 1 day, 2 days, 3 days, a week, comprising: platelet activation rate, prothrombin time, INR, activated partial thromboplastin time, fibrinogen, plasma viscosity, WBV: lowly to cut, WBV: the item indexs such as height is cut, erythrocyte sedimentation rate, erythrocyte aggregation, packed cell volume.
4, for open space control rats, when earth magnetism is quiet, the physical signs of rat is gathered, comprising: platelet activation rate, prothrombin time, INR, activated partial thromboplastin time, fibrinogen, plasma viscosity, WBV: lowly to cut, WBV: the item indexs such as height is cut, erythrocyte sedimentation rate, erythrocyte aggregation, packed cell volume;
5, get the coronary branches of rat during the simulation earth magnetism pediocratic and observe atheromatous plaque situation, measurement of comparison emulates the patch of different earth magnetism detonator signal radiation experiments group rat, analyzes plaques stabilize situation.
Under contrasting above-mentioned different radiation condition, the change of every physical signs.
The rat in open space is being compared to period without geomagnetic activity, the rat of analog magnetic field irradiation group, prothrombin time and activated partial thromboplastin time will reduce, and all the other indexs are as platelet activation rate, fibrinogen, plasma viscosity, WBV: lowly to cut, WBV: height is cut, erythrocyte sedimentation rate, erythrocyte aggregation, packed cell volume etc. will obviously rise.
Claims (4)
1. simulate a biological experiment platform for earth magnetism outburst, it is characterized in that: comprise main control computer, signal generator, metallic shield cage, radiating antenna; Main control computer is connected with signal generator by transmission cable, and signal generator is connected with metallic shield cage by signal cable, and the radiating antenna of more than is arranged in metallic shield cage, and radiating antenna placement direction is consistent with direction, earth's magnetic field;
Described metallic shield cage is metal grill cube cage, and its online hole size is 0.25-4cm
2, metallic shield cage top has door.
2. the biological experiment platform of simulation earth magnetism outburst according to claim 1, is characterized in that: signal generator controls generation 50Hz by main control computer and following signal spectrum combines.
3. the biological experiment platform of simulation earth magnetism outburst according to claim 1 and 2, is characterized in that: the root-mean-square value of signal generator electric-field strength is 0.22-1.12 mV/m, and power is 0.013-0.33 pW/cm
2.
4. the biological experiment platform of simulation earth magnetism outburst according to claim 3, is characterized in that: the signal noise in metallic shield cage is 10000nT-50000nT.
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| CN107167671A (en) * | 2017-06-13 | 2017-09-15 | 华东师范大学 | Animal electromagnetic radiation test device based on monitoring mobile phone |
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| US20080196673A1 (en) * | 2007-02-20 | 2008-08-21 | Cudia Ariel S | Magnetic cage |
| US8844470B2 (en) * | 2010-09-27 | 2014-09-30 | Aspect Imaging Ltd | Maneuverable bed for analyzed objects |
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