CN104777020B - Stirring before a kind of homogenate for biological tissue smashes device - Google Patents
Stirring before a kind of homogenate for biological tissue smashes device Download PDFInfo
- Publication number
- CN104777020B CN104777020B CN201510151407.9A CN201510151407A CN104777020B CN 104777020 B CN104777020 B CN 104777020B CN 201510151407 A CN201510151407 A CN 201510151407A CN 104777020 B CN104777020 B CN 104777020B
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- vessel
- smash
- mobile platform
- workbench
- nest
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Abstract
Device is smash the invention discloses stirring before a kind of homogenate for biological tissue, including workbench, it is connected by hollow column with base, it is mobile platform between workbench and base, pass through the one below Pneumatic power elevator apparatus being connected with base, and platform side and the cylindrical arc guide groove matched in hollow column part, realize the adjustment of mobile platform upper-lower position；Provided with transmission vertical shaft in hollow column, the switching transmitting mechanism anyhow in the connect base of lower end；Puddler structure in upper end connection workbench, multiple the stirring for the belt blade heads for stretching out workbench lower surfaces of puddler structure driving smash device and are horizontally rotated and swung up and down；Mobile platform is provided with and stirs multiple recessed vessel nests that to smash device quantity suitable, is respectively aligned to one and stirs smash device cutter head, installation tissue vessel and fixation in nest；Smash when stirring, Pneumatic power elevator apparatus moves up mobile platform, make to stir and smash device cutter head and put in corresponding tissue vessel.
Description
Technical field
The present invention relates to it is a kind of medical teaching test and scientific experiment in be used for biological tissue be homogenized, it is broken before cracking
Device
Background technology
In recent years, with the development that deepens continuously of medical science, it is engaged in albumen research the most extensive.As protein,
The main process in DNA, RNA source is exactly to select tissue, tissue mashing, tissue homogenate, several processes of Tissue Lysis, still, mesh
It is all manual operations that the method for preceding tissue mashing is most of at present, is operated comparatively laborious, the duration is longer, efficiency ratio
It is relatively low.
The content of the invention
The present invention for the problems of background technology there is provided one kind it is simple, convenient, fast, efficiently and can meet
The device for the tissue mashing that many groups, multisample are carried out simultaneously, can be greatly reduced experimenter's labor intensity, be next step experiment
The quick carry out saving time.
To achieve the above objectives, the present invention, which is adopted the following technical scheme that, is achieved：
Stirring before a kind of homogenate for biological tissue smashes device, including three parts being parallel to each other from top to bottom：Work is flat
Platform, mobile platform, base, the workbench are connected by hollow column with base, and mobile platform is placed in workbench and bottom
Between seat, mobile platform passes through the one below Pneumatic power elevator apparatus being connected with base, and platform side and hollow column
The cylindrical arc guide groove matched in part, realizes the adjustment of mobile platform upper-lower position；It is vertical provided with a transmission in hollow column
One in axle, lower end connect base is by motor-driven switching transmitting mechanism anyhow；One in upper end connection workbench
Puddler structure, puddler structure driving is multiple to stretch out stirring for workbench lower surfaces and smashes device and horizontally rotated and swung up and down；
Respectively stir and smash device lower end and be all connected with a Demountable metallic cutter head；The mobile platform upper surface is provided with and stirs that to smash device quantity suitable
Multiple recessed vessel nests, each vessel nest stirs with respect to one on workbench and smashes device cutter head, installs and contains in the vessel nest
The tissue vessel of biological tissue are put, the tissue vessel ware shape matches with vessel nest, pass through the positioning on the vessel nest nest side
Device will organize vessel to be fixed in the vessel nest；Smash when stirring, mobile platform is moved up by Pneumatic power elevator apparatus, makes corresponding stir
Device cutter head is smash to put in the tissue vessel in the vessel nest.
In such scheme, described puddler structure include multiple driven gears in one line in workbench, one with
The driving gear of transmission vertical shaft upper end connection, one with being driven the switching transmitting mechanism anyhow that vertical shaft top is connected；It is described each
Driven gear connection one, which is stirred, smashes device, and first driven gear close to driving gear is meshed with driving gear and turned first
It is dynamic；Be equipped between other each driven gears one by transmission vertical shaft provide driving clutch gear, so as to sequentially be second,
3rd ..., last driven gear provide engagement and make thereon stir smash device rotation；Anyhow the switching transmitting mechanism connects
A trunnion axis is connect, support of the trunnion axis by being fixed on two ends in workbench rotates, and drives multiple cam rotations thereon,
Acted above with respect to one driven gear of each cam, so that make while the driven tooth crop rotation is horizontally rotated again above and below
Move by a small margin, realization, which is stirred, smashes stirring, smashing dual-use function for device.
Anyhow the switching transmitting mechanism is a pair of bevel gears for being mutually perpendicular to engage.
The Pneumatic power elevator apparatus is driven by an air pump in base, mobile platform is moved up and down and is positioned.It is described
Air pump is also connected with a cleaning device, cleaning device is got water under high pressure to provide air pressure, and vessel nest is carried out by sparge pipe
Rinse, the filthy water after flushing connects the pipeline outflow at these vessel nest nest bottoms from one in mobile platform.
Ice chest is provided with the mobile platform.
Compared with prior art, it is an advantage of the invention that being accurately positioned mobile platform upper-lower position by pneumatic means, with
And smashing on workbench stirs the device accurate match mutual with tissue vessel fixed in vessel nest on mobile platform, with reference to tune
The rotating speed of section motor can realize that tissue mashing speed is freely adjusted, the quality of historrhexis is obviously improved, operating efficiency is significantly carried
It is high.In addition, setting Dao Jiao mechanisms and can be increased by multiple gear drives and Combined clutch on the basis of routinely blending
The function of smashing, and can select to smash the species for stirring tissue samples as needed.
Brief description of the drawings
Fig. 1 is overall structure figure of the invention.
Fig. 2 is the tissue vessel structure chart being placed in Fig. 1 vessel nest 14.
In Fig. 1, Fig. 2：1st, a left side is stood to bearing；2nd, cam；3rd, the right side is stood to bearing；4th, driving gear；5th, upper horizontal bearing；6、
It is driven vertical shaft；7th, hollow column；8th, lower horizontal bearing；9th, buncher；10th, cleaning device；11st, button is regulated and controled；12nd, spray water
Pipe；13rd, mobile platform；14th, vessel nest；15th, cutter head；16th, support；17th, clutch gear；18th, air pump；19th, base；20th, work
Platform；21st, Pneumatic power elevator apparatus；22nd, arc guide groove；23rd, locating slot；24th, catch；25th, bevel gear pair；26th, ware body；27th, it is fixed
Position ear.
Embodiment
With reference to Fig. 1, stirring before a kind of homogenate for biological tissue smashes device, including three be parallel to each other from top to bottom
Point：Workbench 20, mobile platform 13, base 19.Workbench is connected by hollow column 7 with base, and mobile platform is placed in
Between workbench and base, mobile platform passes through the one below Pneumatic power elevator apparatus 21 being connected with base, and its side
Face and the cylindrical arc guide groove 22 matched in hollow column part, realize the adjustment of mobile platform position.One is provided with base
Smash device to stir the motor 9 (buncher) of power, an air pump 18 be provided, the air pump connects Pneumatic power elevator apparatus to drive shifting
Moving platform is moved up and down；The air pump is also connected with a cleaning device 10, cleaning device is got water under high pressure to provide air pressure, passes through
Sparge pipe 12 is rinsed (the filthy water pipeline that one connects these nest bottoms out of the platform outflow after flushing) to vessel nest 14.Bottom
The outside regulation and control button 11 for being provided with the rotating speed of controlled motor 9, control air pump 18 and Pneumatic power elevator apparatus 21 of seat.
Provided with a transmission vertical shaft 6 in hollow column 7, lower end is by setting the connection of lower horizontal bearing 8 one in the base
The bevel gear of Vertical Meshing is to 25；Upper end connects driving gear 4 by the upper horizontal bearing 5 in workbench；Bevel gear group 25
Driving gear by setting motor 9 in the base to drive.Multiple driven gear (this reality in one line are provided with workbench
Example is applied for four), each driven gear, which connects one and stirred, smashes the lower surface that device stretches out workbench, respectively stirs and smashes device lower end and be all connected with
One Demountable metallic cutter head 15, it can be inverted cone-shaped that it, which is constructed, and its rat has the multiple axial cutters being evenly distributed
Sword.
First driven gear close to driving gear is meshed with driving gear 4 and rotated first；And it is other each driven
Be equipped between gear one by transmission vertical shaft provide driving clutch gear 17, can sequentially for second, the 3rd ...,
Last driven gear provide engagement and make its drive be connected thereto stir smash device rotation.On transmission vertical shaft 6 in workbench
End can be by the bevel gear of another Vertical Meshing to connecting a trunnion axis, and the trunnion axis is by being fixed on two ends in workbench
The rotation of support 16 (can be respectively provided with a left side and stand to bearing 1, the right side and stand to bearing 3) in two supports, drive 2 turns of multiple cams thereon
It is dynamic, with respect to one driven gear of each cam, so as to small make while the driven gear is being horizontally rotated again above and below
Amplitude is moved, and realization, which is stirred, smashes stirring, smashing dual-use function for device.
The upper surface of mobile platform 13 is provided with multiple recessed vessel nests 14, and each vessel nest is stirred with respect to one on workbench
Device cutter head 15 is smash, the mobile platform surface on each vessel nest nest side is equipped with a locating slot 23 and is connected with vessel nest, and locating slot is attached
It is near to be provided with a catch 24.
With reference to Fig. 2, for holding object of the tissue vessel of biological tissue for the spoon shape that bails, its ware body 26 and vessel
The shape of nest matches, and with a chucking lug 27.Stir when smashing, ware body is just put into vessel nest, and chucking lug is put
In in the locating slot of the vessel nest, catch 24 is then stirred, so that it may which chucking lug 27 is stuck in locating slot 23, and then make ware body
It is fixed in vessel nest.Then mobile platform 13 is risen by Pneumatic power elevator apparatus and positioned to stirring to smash device cutter head and put in and wait to stir
In the tissue vessel smash, unlatching motor 9 drives transmission system to make first to stir and smashes device realization in corresponding first tissue vessel
Work is smash in stirring for particular organization；Then by clutch selectivity realize two or more stir smash device to each tissue vessel in not
Stirred with tissue progress simultaneously and smash work.Stir during smashing, can realize to stir come controlled motor rotating speed by regulation regulation and control button 11 and smash
Rhythm.Stir and smash after end, close motor, and decline mobile platform 13 by Pneumatic power elevator apparatus, stir and smash device cutter head and exit
Vessel are organized, tissue vessel are then taken out from mobile platform；Again from stir smash unloaded on device cutter head (with tissue vessel together with separately
Cleaning)；Start cleaning device, each vessel nest is rinsed well with sparge pipe, smashes not contaminated to stir next time.
When apparatus of the present invention come into operation, ice chest can be provided with mobile platform 13, to keep on platform in each vessel nest
The biological tissue smash is stirred in stable low temperature environment in ware body.
Claims (4)
1. stirring before a kind of homogenate for biological tissue smashes device, including three parts being parallel to each other from top to bottom：Workbench,
Mobile platform, base, it is characterised in that the workbench is connected by hollow column with base, and mobile platform is placed in work
Between platform and base, mobile platform by the one below Pneumatic power elevator apparatus being connected with base, and platform side with
The cylindrical arc guide groove matched in hollow column part, realizes the adjustment of mobile platform upper-lower position；One is provided with hollow column
One in individual transmission vertical shaft, lower end connect base is by motor-driven switching transmitting mechanism anyhow；Upper end connects workbench
In a puddler structure, the puddler structure driving it is multiple stretch out workbench lower surfaces stir smash device horizontally rotated and on
Lower swing；Respectively stir and smash device lower end and be all connected with a Demountable metallic cutter head；The mobile platform upper surface is provided with and smashes device with stirring
The suitable multiple recessed vessel nests of quantity, each vessel nest stirs with respect to one on workbench and smashes device cutter head, the vessel nest
Interior to install the tissue vessel for holding biological tissue, the tissue vessel ware shape matches with vessel nest, passes through the vessel nest nest
The locator on side will organize vessel to be fixed in the vessel nest；Smash when stirring, mobile platform is moved up by Pneumatic power elevator apparatus, made
Corresponding stir is smash device cutter head and put in the tissue vessel in the vessel nest；
Described puddler structure is connected including multiple driven gears in one line in workbench, one with transmission vertical shaft upper end
Driving gear, the switching transmitting mechanism anyhow that is connected with transmission vertical shaft top；Each driven gear connects one
Stir and smash device, first driven gear close to driving gear is meshed with driving gear and rotated first；Other each driven gears
Between be equipped with one by transmission vertical shaft provide driving clutch gear, so as to sequentially be second, the 3rd ..., last
Individual driven gear provides engagement and makes stirring and smash device rotation thereon；Anyhow the switching transmitting mechanism connects a trunnion axis, the water
Support of the flat axle by being fixed on two ends in workbench rotates, and drives multiple cam rotations thereon, each cam is relative
Acted above one driven gear, so that make to move by a small margin up and down again while the driven tooth crop rotation is horizontally rotated, it is real
Now stir and smash stirring, smashing dual-use function for device.
2. stirring before being homogenized as claimed in claim 1 for biological tissue smashes device, it is characterised in that the conversion anyhow is passed
Motivation structure is a pair of bevel gears for being mutually perpendicular to engage.
3. stirring before being homogenized as claimed in claim 1 for biological tissue smashes device, it is characterised in that the Pneumatic elevation dress
Put by the air pump driving in base, the air pump is also connected with a cleaning device, cleaning device is got height to provide air pressure
Water is pressed, vessel nest is rinsed by sparge pipe, the filthy water after flushing connects these vessel nests from one in mobile platform
The pipeline outflow at nest bottom.
4. stirring before being homogenized as claimed in claim 1 for biological tissue smashes device, it is characterised in that in the mobile platform
Provided with ice chest.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510151407.9A CN104777020B (en) | 2015-04-01 | 2015-04-01 | Stirring before a kind of homogenate for biological tissue smashes device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510151407.9A CN104777020B (en) | 2015-04-01 | 2015-04-01 | Stirring before a kind of homogenate for biological tissue smashes device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104777020A CN104777020A (en) | 2015-07-15 |
| CN104777020B true CN104777020B (en) | 2017-10-10 |
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ID=53618629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510151407.9A Expired - Fee Related CN104777020B (en) | 2015-04-01 | 2015-04-01 | Stirring before a kind of homogenate for biological tissue smashes device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104777020B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220050027A1 (en) * | 2020-08-11 | 2022-02-17 | Vietnam National University Ho Chi Minh City | Laboratory (lab) grinders capable of simultaneously grinding multiple samples without cross-contamination and method of grinding lab samples |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62278426A (en) * | 1986-05-27 | 1987-12-03 | Torai Eng Kk | Concrete sample maker |
| CN201735439U (en) * | 2010-05-31 | 2011-02-09 | 向开兴 | Overhead sterile high-speed tissue blender |
| CN201735433U (en) * | 2010-05-31 | 2011-02-09 | 向开兴 | Underneath type high-capacity aseptic tissue triturator |
| CN202362194U (en) * | 2011-10-31 | 2012-08-01 | 深圳迈瑞生物医疗电子股份有限公司 | Stirring and uniformly mixing device of sample analyzer |
| CN103357478A (en) * | 2012-03-29 | 2013-10-23 | 希森美康株式会社 | Homogenizer and storage cooler |
| CN203772618U (en) * | 2014-06-25 | 2014-08-13 | 中纺协检验（泉州）技术服务有限公司 | Sweat stain sample hitting machine |
| CN204556350U (en) * | 2015-04-01 | 2015-08-12 | 中国人民解放军第四军医大学 | A kind ofly smash device for stirring before biological tissue's homogenate |
-
2015
- 2015-04-01 CN CN201510151407.9A patent/CN104777020B/en not_active Expired - Fee Related
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62278426A (en) * | 1986-05-27 | 1987-12-03 | Torai Eng Kk | Concrete sample maker |
| CN201735439U (en) * | 2010-05-31 | 2011-02-09 | 向开兴 | Overhead sterile high-speed tissue blender |
| CN201735433U (en) * | 2010-05-31 | 2011-02-09 | 向开兴 | Underneath type high-capacity aseptic tissue triturator |
| CN202362194U (en) * | 2011-10-31 | 2012-08-01 | 深圳迈瑞生物医疗电子股份有限公司 | Stirring and uniformly mixing device of sample analyzer |
| CN103357478A (en) * | 2012-03-29 | 2013-10-23 | 希森美康株式会社 | Homogenizer and storage cooler |
| CN203772618U (en) * | 2014-06-25 | 2014-08-13 | 中纺协检验（泉州）技术服务有限公司 | Sweat stain sample hitting machine |
| CN204556350U (en) * | 2015-04-01 | 2015-08-12 | 中国人民解放军第四军医大学 | A kind ofly smash device for stirring before biological tissue's homogenate |
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| Publication number | Publication date |
|---|---|
| CN104777020A (en) | 2015-07-15 |
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| PB01 | Publication | ||
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| SE01 | Entry into force of request for substantive examination | ||
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| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20171010 Termination date: 20180401 |