CN104744835A - 一种原料药用丁基橡胶塞 - Google Patents

一种原料药用丁基橡胶塞 Download PDF

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Publication number
CN104744835A
CN104744835A CN201510095175.XA CN201510095175A CN104744835A CN 104744835 A CN104744835 A CN 104744835A CN 201510095175 A CN201510095175 A CN 201510095175A CN 104744835 A CN104744835 A CN 104744835A
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China
Prior art keywords
butyl rubber
parts
rubber plug
crude drug
brominated
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CN201510095175.XA
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English (en)
Inventor
田恒生
马正平
黄家萍
王荣祥
许冰
陶良锦
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ANHUI HUAFENG PHARMACEUTICAL RUBBER Co Ltd
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ANHUI HUAFENG PHARMACEUTICAL RUBBER Co Ltd
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Priority to CN201510095175.XA priority Critical patent/CN104744835A/zh
Publication of CN104744835A publication Critical patent/CN104744835A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K13/00—Use of mixtures of ingredients not covered by one single of the preceding main groups, each of these compounds being essential
    • C08K13/02—Organic and inorganic ingredients
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/02—Elements
    • C08K3/04—Carbon
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/02—Elements
    • C08K3/06—Sulfur
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/18—Oxygen-containing compounds, e.g. metal carbonyls
    • C08K3/20—Oxides; Hydroxides
    • C08K3/22—Oxides; Hydroxides of metals
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/34—Silicon-containing compounds
    • C08K3/346—Clay
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/18—Oxygen-containing compounds, e.g. metal carbonyls
    • C08K3/20—Oxides; Hydroxides
    • C08K3/22—Oxides; Hydroxides of metals
    • C08K2003/2217—Oxides; Hydroxides of metals of magnesium
    • C08K2003/222—Magnesia, i.e. magnesium oxide
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/18—Oxygen-containing compounds, e.g. metal carbonyls
    • C08K3/20—Oxides; Hydroxides
    • C08K3/22—Oxides; Hydroxides of metals
    • C08K2003/2237—Oxides; Hydroxides of metals of titanium
    • C08K2003/2241—Titanium dioxide

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

本发明公开了一种原料药用丁基橡胶塞，所述丁基橡胶塞以100份溴化丁基橡胶计，各组分的配比是：溴化丁基橡胶：100，高岭土：65-85，炭黑：0.1，钛白粉：3，活性氧化镁：5-8，硫磺：0.1-0.4，硫化助剂HA：0.5-2。本发明具有产品性能良好，生产成本低、质量高的优点。

Description

一种原料药用丁基橡胶塞
技术领域
本发明涉及药用密封件技术领域，具体涉及一种原料药用丁基橡胶塞。
背景技术
原料药用丁基橡胶塞的是用于药品分装前的原料药的封装，此产品的特点是产品尺寸大，制品厚度大。因制品较大，胶料易流动，易出模，因此我们需要使用合适的硫化体系保证产品的硫化成熟性的同时，改善丁基橡胶塞的配方。
发明内容
为解决上述问题，本发明提供一种原料药用丁基橡胶塞，它具有性能稳定，生产成本低，产品质量高的优点。
本发明所要解决的技术问题采用以下技术方案来实现：
一种原料药用丁基橡胶塞，所述丁基橡胶塞以100份溴化丁基橡胶计，各组分的配比是：
溴化丁基橡胶：100，
      高岭土：65-85，
      炭黑：0.1，
      钛白粉：3，
      活性氧化镁：5-8，
      硫磺：0.1-0.4，
      硫化助剂HA：0.5-2。
本发明的有益效果是：本发明性能稳定，生产成本低，产品质量高，保证能满足较长时间硫化不出现返原现象，使产品产品的硫化成熟。
具体实施方式
为了使本发明实现的技术手段、创作特征、达成目的与功效易于明白了解，下面结合具体实施例，进一步阐述本发明。
实施例一：
一种原料药用丁基橡胶塞，所述丁基橡胶塞以100份溴化丁基橡胶计，各组分的配比是：
溴化丁基橡胶：100，
      高岭土：65，
      炭黑：0.1，
      钛白粉：3，
      活性氧化镁：5，
      硫磺：0.1，
      硫化助剂HA：0.5。
经实验得出，产品性能良好，生产成本低。
实施例二：
一种原料药用丁基橡胶塞，所述丁基橡胶塞以100份溴化丁基橡胶计，各组分的配比是：
溴化丁基橡胶：100，
      高岭土：75，
      炭黑：0.1，
      钛白粉：3，
      活性氧化镁：6.5，
      硫磺：0.25，
      硫化助剂HA：1.25。
经实验得出，产品性能良好，生产成本低。
实施例三：
一种原料药用丁基橡胶塞，所述丁基橡胶塞以100份溴化丁基橡胶计，各组分的配比是：
溴化丁基橡胶：100，
      高岭土： 85，
      炭黑：0.1，
      钛白粉：3，
      活性氧化镁： 8，
      硫磺： 0.4，
      硫化助剂HA： 2。
经实验得出，产品性能良好，生产成本低。
以上显示和描述了本发明的基本原理和主要特征以及本发明的优点。本行业的技术人员应该了解，本发明不受上述实施例的限制，上述实施例和说明书中描述的只是说明本发明的原理，在不脱离本发明精神和范围的前提下，本发明还会有各种变化和改进，这些变化和改进都落入要求保护的本发明范围内。本发明要求保护范围由所附的权利要求书及其等效物界定。

Claims (1)

1.一种原料药用丁基橡胶塞，其特征在于：所述丁基橡胶塞以100份溴化丁基橡胶计，各组分的配比是：
溴化丁基橡胶：100，
      高岭土：65-85，
      炭黑：0.1，
      钛白粉：3，
      活性氧化镁：5-8，
      硫磺：0.1-0.4，
      硫化助剂HA：0.5-2。
CN201510095175.XA 2015-03-04 2015-03-04 一种原料药用丁基橡胶塞 Pending CN104744835A (zh)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105137051A (zh) * 2015-09-15 2015-12-09 湖北华强科技有限责任公司 一种输液胶塞与药物相容性快速评价方法
CN106198426A (zh) * 2016-07-01 2016-12-07 郑州翱翔医药科技股份有限公司 紫外吸光度评价注射用无菌粉末用胶塞洁净度的检测方法
CN106188720A (zh) * 2016-08-29 2016-12-07 樊之雄 一种医用抗菌耐针刺橡胶塞及其制备方法

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105137051A (zh) * 2015-09-15 2015-12-09 湖北华强科技有限责任公司 一种输液胶塞与药物相容性快速评价方法
CN106198426A (zh) * 2016-07-01 2016-12-07 郑州翱翔医药科技股份有限公司 紫外吸光度评价注射用无菌粉末用胶塞洁净度的检测方法
CN106188720A (zh) * 2016-08-29 2016-12-07 樊之雄 一种医用抗菌耐针刺橡胶塞及其制备方法
CN106188720B (zh) * 2016-08-29 2017-11-10 蒋吉明 一种医用抗菌耐针刺橡胶塞及其制备方法

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Application publication date: 20150701