CN104740771A - Bioenergy brain pacemaker - Google Patents

Bioenergy brain pacemaker Download PDF

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Publication number
CN104740771A
CN104740771A CN201310733312.9A CN201310733312A CN104740771A CN 104740771 A CN104740771 A CN 104740771A CN 201310733312 A CN201310733312 A CN 201310733312A CN 104740771 A CN104740771 A CN 104740771A
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CN
China
Prior art keywords
main body
bioenergy
brain pacemaker
generating main
electrode
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201310733312.9A
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Chinese (zh)
Inventor
张�浩
曲丹
徐志云
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Second Military Medical University SMMU
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Second Military Medical University SMMU
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Application filed by Second Military Medical University SMMU filed Critical Second Military Medical University SMMU
Priority to CN201310733312.9A priority Critical patent/CN104740771A/en
Publication of CN104740771A publication Critical patent/CN104740771A/en
Pending legal-status Critical Current

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Abstract

The invention provides a bioenergy brain pacemaker, comprising a pulse generator and exciting electrodes. The bioenergy brain pacemaker is characterized by also comprising an electricity generation portion which comprises an electricity generation main body, two adjusting ends, an output electrode, a macromolecule packaging material and an electric energy accumulation unit. The electricity generation main body is used to surround the aorta, so as to acquire mechanical energy generated when the aorta expands, and converts the mechanical energy to electric energy. The electricity generation main body is in a multilayered film structure. The electricity generation main body comprises a piezoelectric layer in a central layer, and a first electrode layer and a second electrode layer respectively on two sides of the piezoelectric layer. The macromolecule packaging material covers surfaces of the electricity generation main body, the adjusting ends, and the output electrode. The two adjusting ends are disposed on two ends of the electricity generation main body and used to adjust the diameter of the electricity generation main body. The output electrode is used to transmit electric energy to the electric energy accumulation unit. The electric energy accumulation unit is used to store electric energy and supply power for the pulse generator and the exciting electrodes. The bioenergy brain pacemaker can be used for whole life without changing cells.

Description

Bioenergy brain pacemaker
Technical field
The present invention relates to a kind of brain pacemaker, belong to medical instruments field.
Background technology
Along with the mankind deepen continuously to the understanding of various disease, increasing disease can adopt implantable electronic device to carry out diagnosing or treating.
Wherein, implant the related neural of brain pacemaker by controlled motion in Stimulation of The Brain, suppress to cause the abnormal signal of Parkinsonian symptoms, alleviate symptoms such as even eliminating the trembling of patient, stiff and slow movement, make it recover original mobility and self-care ability.But the battery of brain pacemaker is 5 ~ 8 years, electricity must change the battery of brain pacemaker by operating mode after exhausting.This both can cause physiological misery and psychological fear and anxiety to patient, also can increase the financial burden of patient and family thereof.
Summary of the invention
For solving the problem, the invention provides a kind of bioenergy brain pacemaker, it is characterized in that, comprising: pulse generator, stimulating electrode and be connected with described pulse generator and be the Power Generation Section that it is powered.Wherein, Power Generation Section comprises generating main body, adjustable side, output electrode, energy storage unit and encapsulated layer.
Wherein, generating main body is used for holding aorta, the mechanical energy produced during to gather aortectasia, and is converted into electric energy.Generating main body is multi-layer film structure, comprises the piezoelectric material layer being positioned at central core, and lays respectively at the first electrode layer and the second electrode lay of piezoelectric material layer both sides.Adjustable side is positioned at the two ends of generating main body, for regulating the length of generating main body.Output electrode is used for electric energy to flow to energy storage unit.Energy storage unit is used for storage of electrical energy also for pulse generator is powered.Encapsulated layer is covered in generating main body, adjustable side, output electrode and energy storage unit surface.
In addition, bioenergy brain pacemaker of the present invention can also have such feature: wherein, and piezoelectric material layer contains nanoscale piezoelectric, and nanoscale piezoelectric is any one in piezoquartz, piezoelectric ceramics and organic piezopolymer.
In addition, bioenergy brain pacemaker of the present invention can also have such feature: wherein, and piezoquartz, piezoelectric ceramics, organic piezopolymer can be the single or multiple lift structure of nanoscale piezoelectric.
In addition, bioenergy brain pacemaker of the present invention can also have such feature: wherein, and power storage portion is miniature rechargeable battery or electric capacity.
In addition, bioenergy brain pacemaker of the present invention can also have such feature: current rectifying and wave filtering circuit, is connected between energy storage unit and output electrode.
In addition, bioenergy brain pacemaker of the present invention can also have such feature: wherein, and the fixed form of adjustable side uses that surgical thread is sewed up, any one in titanium clamp pincers folder or binding agent bonding.
In addition, bioenergy brain pacemaker of the present invention can also have such feature: wherein, one end of adjustable side is single latch, the tip of this latch is level and smooth and towards the outside of generating main body, the other end of adjustable side is draw-in groove, the side, inside of draw-in groove has the teeth groove matched with latch, and opposite side is plane, and latch and draw-in groove fasten.
In addition, bioenergy brain pacemaker of the present invention can also have such feature: wherein, and encapsulated layer is using the flexible macromolecule insulant of good biocompatibility as encapsulating material.
In addition, bioenergy brain pacemaker of the present invention can also have such feature: Power Generation Section is less than 140mmHg to aortal pressure.
Invention effect and effect
Bioenergy brain pacemaker of the present invention, the energy produced during by implanting nanoscale piezoelectric to gather aortectasia is also converted into electric energy, as its energy source.As long as therefore heartbeat, the present invention can utilize the bioenergy of patient self to provide electric energy, eliminates the necessity using battery as power supply, solves after the energy content of battery is exhausted and passes through the problem that battery is changed in operation.
Because the present invention adopts nanoscale piezoelectric as generating main body, not only effectively the bioenergy in body can be converted into electric energy, and volume is small, is more suitable for et al. Ke.
Aortal outer wall is paperwrapped in owing to present invention employs soft loop configuration, and can fixing quantity native system to aortal pressure, the mechanical energy produced when therefore both can gather aortectasia efficiently, fully, can not produce obviously impact to cardiac function again.
In addition, because the present invention adopts the flexible macromolecule insulant of good biocompatibility to encapsulate, therefore generating main body and internal milieu can be isolated, also the pressure that aorta wall deformation produces effectively can be conducted to piezoelectric.
In addition, the adjustable side adjustable generating main body at generating main body two ends is utilized to hold aortal tensity, thus the deformation degree of adjustable piezoelectric material and output electricity.Again owing to not containing piezoelectric and electrode layer in adjustable side, therefore use sutures or the clamping timing of titanium can not damage the structure of generating main body.
Further, because generating main body of the present invention is positioned at aorta outside, directly do not contact with blood, thus there is not the risk of thrombosis and apoplexy (myocardial infarction or cerebral infarction).
Accompanying drawing explanation
Fig. 1 is the schematic diagram of the bioenergy brain pacemaker of the embodiment of the present invention one;
Fig. 2 is the schematic diagram of the generating main body of the embodiment of the present invention one;
Fig. 3 is the internal structure profile of the generating main body of the embodiment of the present invention one;
Fig. 4 is the partial enlarged drawing in main body A region of generating electricity in Fig. 3;
Fig. 5 is that the main body that generates electricity in the embodiment of the present invention one is installed on Supraaortic sectional view;
Fig. 6 is that in the embodiment of the present invention four, adjustable side is the schematic diagram of reciprocal latch structure;
Fig. 7 is the circuit diagram of the embodiment of the present invention one.
Detailed description of the invention
Below with reference to the accompanying drawings the specific embodiment of the present invention is described,
< embodiment one >
Fig. 1 is the schematic diagram of the bioenergy brain pacemaker of the embodiment of the present invention one, and as shown in Figure 1, bioenergy brain pacemaker 10 comprises Power Generation Section 200, pulse generator 15, and stimulating electrode 16.Power Generation Section 200 comprises generating main body 11, output electrode 14, current rectifying and wave filtering circuit 12 and energy storage unit 13.Generating main body 11 is resilient loop configuration, can be surrounded on aorta 18 around, and generating main body 11 inside is nanoscale piezoelectric, and aortal deformation therefore can be utilized to produce electric energy.The output electrode 14 of generating main body is connected to current rectifying and wave filtering circuit 12 below.After energy storage unit 13 is connected to current rectifying and wave filtering circuit 12, for electrical power storage is got up, for pulse generator 15.Pulse generator 15 has two stimulating electrodes 16, for implanting intracranial.When heart 17 is beated, the outer wall of aorta 18 shrinks and diastole due to the periodic pressure of blood flow, thus periodically produces pressure to generating main body 11.
Fig. 2 is the schematic diagram of the generating main body of the embodiment of the present invention, as shown in Figure 2, the original state of generating main body 11 is the shape of open loop, respectively having an adjustable side 23, needing two adjustable sides to link together when being arranged on aorta outer wall at the two ends of annular opening.Encapsulated layer 22 is coated with at the outer surface of generating main body 11 and adjustable side 23.Generating main body is connected with two output electrodes 14, exports for electric energy generating main body 11 produced.
Fig. 3 is the internal structure profile of the generating main body of the embodiment of the present invention, as shown in Figure 3, the inside of generating main body 11 is multi-layer film structure, comprises the nanoscale piezoelectric 111 being positioned at main center's layer, and lays respectively at the first electrode layer 112 and the second electrode lay 113 of piezoelectric both sides.Encapsulated layer 22 adopts the flexible macromolecule insulant with biocompatibility, is covered in the surface of generating main body 11 and output electrode 14, and extends to form each adjustable side 23, both sides to the outside of generating main body 11.
Fig. 4 is the partial enlarged drawing in main body A region of generating electricity in Fig. 3, as shown in Figure 4, is positioned at the nanoscale piezoelectric 111 of generating main body 11 central core.First electrode layer 112 and the second electrode lay 113 adopt the high layer material of the conductivity such as gold or silver to make, and are connected with nanoscale piezoelectric 111.
Generating main body 11 is bending circulus in its natural state, and its membrane structure has good elasticity, holds aorta therefore, it is possible to submissive.
When implanting in vivo, can generating main body 11 be implanted to around aorta by operating method and hold aorta.By adjustment adjustable side 23, generating main body 11 is fitted tightly, to gather the energy that aorta deformation produces with aortal outer wall again.
The workload of heart 17 may be increased aortal excessive compressing, therefore can to measure the main body 11 that generates electricity to aortal pressure, avoid it to exert an adverse impact to heart by interim placement force sensor between generating main body 11 and aorta wall.
Because the inside of adjustable side 23 is not containing piezoelectric material layer and electrode layer, therefore when using sutures or titanium folder is closed the both sides of adjustable side 23, can not cause damage to generating main body 11.
Fig. 5 is that the main body that generates electricity in the embodiment of the present invention is installed on Supraaortic sectional view, and the work process of bioenergy brain pacemaker is described below in conjunction with Fig. 1 and Fig. 5.
As shown in Figure 1 and Figure 5, the main body 11 that generates electricity is surrounded on aorta 18.When heart 17 shrinks, the impact of blood flow makes aorta 18 expand, as shown in Figure 5, aorta wall 45 can produce a pressure F to generating main body 11, make piezoelectric material layer 111 that deformation occur, thus form electric potential difference and generation current at its two ends, electric current conducts to output electrode 14 by the first electrode layer 112 and the second electrode lay 113, again by entering energy storage unit 13 after current rectifying and wave filtering circuit 12, electric energy energy memory element 13 is miniature rechargeable battery.Energy storage unit 13 again by supply of electrical energy to pulse generator 15.
Fig. 7 is the circuit diagram of the embodiment of the present invention.As shown in Figure 7, generating main body 11 is connected with current rectifying and wave filtering circuit 12, the electric energy that generating main body 11 produces charges to energy storage unit 13 after current rectifying and wave filtering circuit 12, and energy storage unit 13 is for powering for the pulse generator 15 in electrical appliance and the present embodiment.
< embodiment two >
In the present embodiment, arranging of the generating shape of main body 11 and adjustable side 23 is in the same manner as in Example 1, and difference part is in the present embodiment, and the piezoelectric material layer of generating main body adopts nanoscale piezoceramic material.
Another one difference part is, in the present embodiment, adjustable side 23 adopts titanium clamping fixed.
< embodiment three >
In the present embodiment, arranging of the generating shape of main body and adjustable side is in the same manner as in Example 1, and difference part is in the present embodiment, and the piezoelectric material layer of generating main body adopts piezopolymer, and adjustable side adopts the mode of binding agent bonding to be fixed.
< embodiment four >
In the present embodiment, arranging of the generating shape of main body and adjustable side is in the same manner as in Example 1, difference part is in the present embodiment, as shown in Figure 6, one end of adjustable side 61 is single latch, crown is level and smooth and towards the outside of generating main body, to prevent the tissues such as crown impair cardiac or aorta.The other end of adjustable side 61 is draw-in groove, and the side, inside of draw-in groove has the teeth groove matched with latch, and opposite side is plane.When aorta outer wall is fixed in Power Generation Section, slowly latch is inserted draw-in groove, use micro pressure sensor to detect generating main body to the pressure of aorta outer wall simultaneously, slowly tighten up latch, until this pressure reaches 120mmHg-140mmHg.
Certain bioenergy brain pacemaker of the present invention is not limited to the design described in above embodiment, and its piezoelectric material layer, electrode layer all can adopt various existing appropriate materials to make with encapsulated layer.

Claims (9)

1. a bioenergy brain pacemaker, is characterized in that, comprising:
Pulse generator, stimulating electrode and
Be connected with described pulse generator and be the Power Generation Section that it is powered,
Wherein, described Power Generation Section comprises generating main body, adjustable side, output electrode, energy storage unit and encapsulated layer,
Described generating main body is used for holding aorta, the mechanical energy produced during to gather aortectasia, and is converted into electric energy,
Described generating main body is multi-layer film structure, comprises the piezoelectric material layer being positioned at central core, and lays respectively at the first electrode layer and the second electrode lay of described piezoelectric material layer both sides,
Described adjustable side is positioned at the two ends of described generating main body, for regulating the length of described generating main body,
Described output electrode is used for electric energy to flow to energy storage unit,
Described energy storage unit is used for storage of electrical energy and powers for described pulse generator and described stimulating electrode,
Described encapsulated layer is covered in described generating main body, described adjustable side, described output electrode, described pulse generator and described stimulating electrode surface.
2. bioenergy brain pacemaker as claimed in claim 1, is characterized in that:
Wherein, described piezoelectric material layer contains nanoscale piezoelectric, and described nanoscale piezoelectric is any one in piezoquartz, piezoelectric ceramics and organic piezopolymer.
3. bioenergy brain pacemaker as claimed in claim 2, is characterized in that:
Wherein, described piezoquartz, piezoelectric ceramics, organic piezopolymer can be the single or multiple lift structure of nanoscale piezoelectric.
4. bioenergy brain pacemaker as claimed in claim 1, is characterized in that:
Wherein, described power storage portion is miniature rechargeable battery or electric capacity.
5. bioenergy brain pacemaker as claimed in claim 1, is characterized in that, also comprise:
Current rectifying and wave filtering circuit, is connected between described energy storage unit and described output electrode.
6. bioenergy brain pacemaker as claimed in claim 1, is characterized in that:
Wherein, the fixed form of described adjustable side uses any one in surgical thread stitching, titanium clamp pincers folder or binding agent bonding.
7. bioenergy brain pacemaker as claimed in claim 1, is characterized in that:
Wherein, one end of described adjustable side is single latch, and the tip of this latch is level and smooth and towards the outside of generating main body, the other end of described adjustable side is draw-in groove, the side, inside of draw-in groove has the teeth groove matched with described latch, and opposite side is plane, and described latch and described draw-in groove fasten.
8. bioenergy brain pacemaker as claimed in claim 1, is characterized in that:
Wherein, described encapsulated layer is using the flexible macromolecule insulant of good biocompatibility as encapsulating material.
9. bioenergy brain pacemaker as claimed in claim 1, is characterized in that:
Described Power Generation Section is less than 140mmHg to aortal pressure.
CN201310733312.9A 2013-12-26 2013-12-26 Bioenergy brain pacemaker Pending CN104740771A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310733312.9A CN104740771A (en) 2013-12-26 2013-12-26 Bioenergy brain pacemaker

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310733312.9A CN104740771A (en) 2013-12-26 2013-12-26 Bioenergy brain pacemaker

Publications (1)

Publication Number Publication Date
CN104740771A true CN104740771A (en) 2015-07-01

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100076517A1 (en) * 2008-09-23 2010-03-25 Mir Imran Energy harvesting mechanism for medical devices
US20100298720A1 (en) * 2009-04-16 2010-11-25 Potkay Joseph Allen In Situ Energy Harvesting Systems for Implanted Medical Devices
CN202086954U (en) * 2011-05-10 2011-12-28 粤北第二人民医院 Cardiac pacemaker
CN203620084U (en) * 2013-12-26 2014-06-04 中国人民解放军第二军医大学 Bioenergy brain pacemaker

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100076517A1 (en) * 2008-09-23 2010-03-25 Mir Imran Energy harvesting mechanism for medical devices
US20100298720A1 (en) * 2009-04-16 2010-11-25 Potkay Joseph Allen In Situ Energy Harvesting Systems for Implanted Medical Devices
CN202086954U (en) * 2011-05-10 2011-12-28 粤北第二人民医院 Cardiac pacemaker
CN203620084U (en) * 2013-12-26 2014-06-04 中国人民解放军第二军医大学 Bioenergy brain pacemaker

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Application publication date: 20150701

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