CN104740763B - Self energizing bladder pacemaker - Google Patents

Self energizing bladder pacemaker Download PDF

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Publication number
CN104740763B
CN104740763B CN201310731811.4A CN201310731811A CN104740763B CN 104740763 B CN104740763 B CN 104740763B CN 201310731811 A CN201310731811 A CN 201310731811A CN 104740763 B CN104740763 B CN 104740763B
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CN
China
Prior art keywords
power generation
main body
generation main
self energizing
heart
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Expired - Fee Related
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CN201310731811.4A
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Chinese (zh)
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CN104740763A (en
Inventor
张�浩
曲丹
郎希龙
徐志云
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Second Military Medical University SMMU
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Second Military Medical University SMMU
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Priority to CN201310731811.4A priority Critical patent/CN104740763B/en
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Abstract

The present invention provides a kind of self energizing bladder pacemaker, it is characterised in that including impulse generator, stimulating electrode and Power Generation Section.Power Generation Section includes power generation main body, output unit, energy storage unit, fixed cell and encapsulated layer.Wherein, power generation main body is multi-layer film structure, including the piezoelectric material layer positioned at power generation main body center and the electrode layer positioned at piezoelectric material layer both sides, and power generation main body is used to produce electric energy by being attached at heart surface to gather cardiac energy.Output unit is connected with electrode layer, and the electric current for power generation main body to be produced is exported to energy storage unit.Energy storage unit is used to store electric energy and power for impulse generator.Fixed cell is located at the edge of power generation main body, for power generation main body to be fixed on into the external membrane of heart.Encapsulated layer is covered in the surface of power generation main body, output unit, energy storage unit and fixed cell.The self energizing bladder pacemaker of the present invention need not change battery, can use all the life.

Description

Self energizing bladder pacemaker
Technical field
The present invention relates to a kind of self energizing bladder pacemaker, belong to medical instruments field.
Background technology
As the mankind deepen continuously to the understanding of various diseases, increasing disease can use implanted electronics Device is diagnosed or treated.
Wherein, bladder pacemaker is by stimulating sacral nerve, adjusting bladder, sphincter and the god at basin bottom related to urination It is reflected, abnormal neural reflex is reached balance again, so as to efficiently control the symptom of urinary dysfunction.Available for because Suffer from various diseases cause urge incontinence, urine urgency-frequency syndrome, non-obstructivity chronic urinary retention, overactive bladder with And interstitial cystitis etc. is through the undesirable patient of effect of conservative treatment.
But, the battery of bladder pacemaker is 5~8 years, and must perform the operation replacing battery after electricity exhaustion.This was both Painful and psychological frightened and anxiety physiologically can be caused to patient, the economy that can also increase patient and its family is born Load.
The content of the invention
To solve the above problems, the present invention provides a kind of self energizing bladder pacemaker, it is characterised in that including pulse generation Device, stimulating electrode and Power Generation Section.Power Generation Section includes power generation main body, output unit, energy storage unit, fixed cell and envelope Fill layer.Wherein, power generation main body is multi-layer film structure, including piezoelectric material layer positioned at power generation main body center and positioned at piezoelectricity The electrode layer of material layer both sides, power generation main body is used to produce electric energy by being attached at heart surface to gather cardiac energy.Output Unit is connected with electrode layer, and the electric current for power generation main body to be produced is exported to energy storage unit.Energy storage unit is used Power in storage electric energy and for impulse generator.Fixed cell is located at the edge of power generation main body, for power generation main body to be fixed on The external membrane of heart.Encapsulated layer is covered in the surface of power generation main body, output unit, energy storage unit and fixed cell.
In addition, in the self energizing bladder pacemaker of the present invention, can also have the feature that:Wherein, power generation main body Be shaped as quadrangle, fixed cell is located at the centre on two narrow sides of quadrangle.
In addition, in the self energizing bladder pacemaker of the present invention, can also have the feature that:Wherein, power generation main body Be shaped as triangle, fixed cell is located at three summits of triangle.
In addition, in the self energizing bladder pacemaker of the present invention, can also have the feature that:Wherein, power generation main body Be shaped as Long Circle.
In addition, in the self energizing bladder pacemaker of the present invention, can also have the feature that:Wherein, piezoelectric Layer contains nanoscale piezoelectric, and nanoscale piezoelectric is times in piezo-electric crystal, piezoelectric ceramics and organic piezopolymer Meaning is a kind of.
In addition, in the self energizing bladder pacemaker of the present invention, can also have the feature that:Wherein, piezo-electric crystal For at least one layer of zinc oxide nano-wire array.
In addition, in the self energizing bladder pacemaker of the present invention, can also have the feature that:Wherein, piezo-electric crystal, Piezoelectric ceramics, organic piezopolymer can be the single or multiple lift structure of nanoscale piezoelectric.
In addition, in the self energizing bladder pacemaker of the present invention, can also have the feature that:Wherein, output unit With output electrode and current rectifying and wave filtering circuit.
The effect of invention and effect
According to the self energizing bladder pacemaker of the present invention, because power generation main body is attached directly to heart surface, therefore, it is possible to The effective contraction by heart deforms upon nanoscale piezoelectric with diastole, so as to be converted into electric energy.As long as therefore heart Bounce, the present invention provides electric energy using the biological energy source of patient itself, eliminates the necessity for using battery as power supply, solves The energy content of battery of having determined needs the problem of battery is changed in operation after exhausting.
Further, since electricity generation system is fixed on the external membrane of heart, a side by the power generation main body of the present invention by the way of point is fixed Face can effectively gather the energy of heart movement generation, on the other hand also the contraction and diastole campaign of heart will not be produced bright Aobvious influence.
, not only can be effectively by internal biological energy source due to the present invention using nanoscale piezoelectric as power generation main body Electric energy is converted into, and volume is small, is more suitable for et al. Ke.
Further, since the present invention is encapsulated using the flexible macromolecule insulating materials of good biocompatibility, therefore it will can send out Electric main body is isolated with vivo environment, can also effectively conduct the heart-shaped pressure for becoming generation to piezoelectric.
Also, because the power generation main body of the present invention is located at heart exterior, do not contacted directly with blood, thus in the absence of thrombus Formed and apoplexy(Miocardial infarction or cerebral infarction)Risk.
Brief description of the drawings
Fig. 1 is that the power generation main body of the self energizing bladder pacemaker of the embodiment of the present invention one is the schematic diagram of quadrangle;
Fig. 2 is the partial section of the power generation main body of the self energizing bladder pacemaker of the embodiment of the present invention one;
Fig. 3 is that the power generation main body of the self energizing bladder pacemaker of the embodiment of the present invention two is the schematic diagram of triangle;
Fig. 4 is that the power generation main body of variation of the present invention is the schematic diagram of Long Circle;And
Fig. 5 is the circuit diagram of the embodiment of the present invention one.
Embodiment
Illustrate the embodiment of self energizing bladder pacemaker of the present invention below in conjunction with accompanying drawing,<Embodiment one>
Fig. 1 is that the power generation main body of self energizing bladder pacemaker in embodiment 1 is the schematic diagram of quadrangle, as shown in figure 1, from Energizing bladder pacemaker 20 has Power Generation Section 200, impulse generator 17 and stimulating electrode 18.Wherein, Power Generation Section 200 includes generating electricity Main body 21, output unit, energy storage unit 16, fixed cell 22 and encapsulated layer.Power generation main body 21 is rectangle, in rectangle Respectively there is a fixed cell 22, for power generation main body 11 to be consolidated with long axis direction along systaltic direction on two narrow sides Due on the external membrane of heart.When being implanted into power generation main body, heart is manifested by way of surgical operation, power generation main body is received along heart The direction of contracting sets and fixed part is sewn on the external membrane of heart so that power generation main body fits with the external membrane of heart, now power generation main body Deformation can be produced with the bounce of heart.
Fixed cell 22 is made up of encapsulated layer, and the inside of fixed cell 22 does not have the generating knot such as electrode or piezoelectric Structure, therefore the electrification structure of power generation main body 21 will not be destroyed when being fixed using suture.Power generation main body 21 is except with fixed cell Remainder is not fixed outside 22 fixations, in favor of enabling power generation main body 21 preferably to send out during heart contraction Raw deformation.Because power generation main body employs rectangle, and installation direction is consistent with systaltic direction, therefore can be very good Gather the mechanical energy that heart contraction is produced.
Output unit has output electrode 14 and current rectifying and wave filtering circuit 15, and output electrode 14 is used to produce power generation main body 21 Electric energy export to energy storage unit 16, before energy storage unit 16 also have current rectifying and wave filtering circuit 15, for defeated The electric current for going out the output of electrode 14 carries out rectifying and wave-filtering.Electric energy is supplied to the arteries and veins of self energizing bladder pacemaker by energy storage unit 16 Rush generator 17.Impulse generator 17 produces high frequency electric pulse stimulates sacral nerve by stimulating electrode 18, so as to adjust and urinate Related bladder, sphincter and the neural reflex at basin bottom, makes abnormal neural reflex reach balance again, so as to efficiently control The symptom of urinary dysfunction.
Fig. 2 is the sectional view of the power generation main body part of the self energizing bladder pacemaker of the embodiment of the present invention, power generation main body 21 For multi-layer film structure, as shown in Fig. 2 the central core of power generation main body 21 is piezoelectric material layer 31, in the present embodiment, piezoresistive material The bed of material 31 is made up of ZnO nanowire array, and the both sides of piezoelectric material layer 31 are respectively electrode layer 32 and electrode layer 33, electrode layer 32 It is connected respectively with output electrode 14 with electrode layer 33(Do not shown in figure).Encapsulated layer 34 is located at electrode layer 32 and electrode layer 33 Outside, encapsulated layer 34 has good insulating properties and biocompatibility.
Fig. 5 is the circuit diagram of the embodiment of the present invention, as shown in figure 5, power generation main body 21 is connected with current rectifying and wave filtering circuit 15, The electric energy that power generation main body 21 is produced charges after current rectifying and wave filtering circuit 15 to energy storage unit 16, energy storage unit 16 for being that the impulse generator in the present embodiment is powered for electrical appliance.
<Embodiment two>
Fig. 3 is that the Power Generation Section of the embodiment of the present invention is the self energizing bladder pacemaker schematic diagram of triangle, as shown in figure 3, The power generation main body 12 of the self energizing bladder pacemaker 11 of the present invention is triangle, and each vertex position of triangle is respectively provided with one Fixed cell 13, output electrode 14 and electrode layer(See Fig. 2)It is connected, current rectifying and wave filtering circuit 15 is connected with output electrode 14, Energy storage unit 16 is used to store the electric energy that Power Generation Section is produced after being connected to current rectifying and wave filtering circuit 15.
Fig. 2 is the sectional view of the self energizing bladder pacemaker of the embodiment of the present invention, as shown in Fig. 2 the center of power generation main body Layer is piezoelectric material layer 31, and piezoelectric material layer 31 is made up of ZnO nanowire array, and the both sides of piezoelectric material layer 31 are respectively electrode Layer 32 and electrode layer 33, electrode layer 32 and electrode layer 33 are connected with output electrode 14 respectively.Encapsulated layer 34 is located at electrode layer electricity The outside of pole layer 32 and electrode layer 33.The surface of actually whole self energizing bladder pacemaker 11 is all covered with one layer of good insulating Encapsulated layer 34, encapsulated layer 34 can be used macromolecule polymeric material, and encapsulated layer 34 has good biocompatibility so that Self energizing bladder pacemaker 11 will not cause rejection when implanting.
As shown in figure 3, power generation main body 12 is shaped as triangle, when being installed on the external membrane of heart, using positioned at three Power generation main body 12 is fixed on the external membrane of heart of myocardial wall by the fixed cell 13 on angular three summits.And the three of power generation main body 12 Each angular side is not fixed, contraction and diastole so both without limitation on heart, additionally aids piezoelectric material layer with the heart Dirty motion deforms upon to produce electric energy.
Power generation main body 12 make triangularity advantage be more gather the energy of heartbeat because The not only contraction and diastole of transverse direction, also has longitudinal contraction and diastole, when using triangle during heartbeat During shape, a summit of triangle is set to the direction towards the apex of the heart, and two other summit is set to laterally receive with heart The direction of contracting is parallel, and so whether heart cross-direction shrinkage is longitudinal contraction, power generation main body 12 can be driven to deform.Therefore The shape of triangle can more utilize the energy of heartbeat generation than the shape of quadrangle.
Fixed cell 13 is extended by encapsulated layer and formed in corresponding position, and the inside of fixed cell 13 does not contain piezoresistive material Material and electrode material, therefore damage piezoelectric material layer and electrode layer in suture can be avoided.
Electric energy is supplied to the energy storage unit 16 of biological energy source self energizing bladder pacemaker by electricity by energy storage unit 16 The impulse generator 17 of self energizing bladder pacemaker can be supplied to.
<Variation>
This variation compared with embodiment one, except power generation main body be shaped as Long Circle in addition to, others set homogeneous Together.As shown in figure 4, power generation main body 42 is shaped as Long Circle, in two apexes of Long Circle there is fixed cell 41, generate electricity The advantage for being shaped as Long Circle of main body 42 is without sharp corner, helps to mitigate the damage to heart.
Certainly, the shape of the power generation main body of self energizing bladder pacemaker of the invention can be various shapes, be not limited only to Triangle, quadrangle and Long Circle in above-mentioned two embodiment.

Claims (9)

1. a kind of self energizing bladder pacemaker, it is characterised in that including:
Impulse generator for producing electro photoluminescence;
It is connected with the impulse generator, and stimulates the stimulating electrode of sacral nerve;And
The Power Generation Section powered for the impulse generator,
Wherein, the Power Generation Section includes power generation main body, output unit, energy storage unit, fixed cell and encapsulated layer,
The power generation main body is multi-layer film structure, including the piezoelectric material layer positioned at the power generation main body center, and is located at The electrode layer of piezoelectric material layer both sides, the power generation main body is attached directly to heart surface to be used to produce electricity to gather cardiac energy Can,
The output unit is connected with the electrode layer, and the electric current for power generation main body to be produced is exported to the power storage Unit,
The energy storage unit is used to store electric energy and powered for the impulse generator,
The fixed cell is located at the edge of the power generation main body, is pasted for power generation main body to be fixed along systaltic direction Together in the external membrane of heart,
The encapsulated layer is covered in the power generation main body, the output unit, the energy storage unit and the fixed list The surface of member.
2. self energizing bladder pacemaker as claimed in claim 1, it is characterised in that:
Wherein, the power generation main body is shaped as quadrangle, and the centre that the fixed cell is located at two narrow sides of quadrangle makes The power generation main body is fixed along the systaltic direction with long axis direction and fits in the external membrane of heart.
3. self energizing bladder pacemaker as claimed in claim 1, it is characterised in that:
Wherein, the power generation main body is shaped as triangle, and three summits that the fixed cell is located at triangle make the hair Fixation fits in the external membrane of heart parallelly with the direction of heart cross-direction shrinkage on two summits of electric main body.
4. self energizing bladder pacemaker as claimed in claim 1, it is characterised in that:
Wherein, the power generation main body is shaped as Long Circle, the fixed cell be located at the Long Circle two summits make it is described Power generation main body is fixed along the systaltic direction with long axis direction and fits in the external membrane of heart.
5. self energizing bladder pacemaker as claimed in claim 1, it is characterised in that:
Wherein, the piezoelectric material layer contains nanoscale piezoelectric, and the nanoscale piezoelectric is piezo-electric crystal, piezoelectricity pottery Any one in porcelain and organic piezopolymer.
6. self energizing bladder pacemaker as claimed in claim 5, it is characterised in that:
Wherein, the piezo-electric crystal is at least one layer of zinc oxide nano-wire array.
7. self energizing bladder pacemaker as claimed in claim 5, it is characterised in that:
Wherein, the piezo-electric crystal, piezoelectric ceramics, organic piezopolymer are single or multiple lift structure.
8. self energizing bladder pacemaker as claimed in claim 1, it is characterised in that:
Wherein, output unit has output electrode and current rectifying and wave filtering circuit.
9. self energizing bladder pacemaker as claimed in claim 1, it is characterised in that:
Wherein, the flexible macromolecule insulating materials of the encapsulated layer using good biocompatibility is used as encapsulating material.
CN201310731811.4A 2013-12-26 2013-12-26 Self energizing bladder pacemaker Expired - Fee Related CN104740763B (en)

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107743408B (en) * 2015-08-05 2021-01-08 波士顿科学医学有限公司 Bladder function control using high frequency pacing

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN202086954U (en) * 2011-05-10 2011-12-28 粤北第二人民医院 Cardiac pacemaker
CN203694402U (en) * 2013-12-26 2014-07-09 中国人民解放军第二军医大学 Self-energized bladder pacemaker

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7729768B2 (en) * 2005-03-25 2010-06-01 Proteus Biomedical, Inc. Implantable cardiac motion powered piezoelectric energy source
US9026212B2 (en) * 2008-09-23 2015-05-05 Incube Labs, Llc Energy harvesting mechanism for medical devices

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN202086954U (en) * 2011-05-10 2011-12-28 粤北第二人民医院 Cardiac pacemaker
CN203694402U (en) * 2013-12-26 2014-07-09 中国人民解放军第二军医大学 Self-energized bladder pacemaker

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