CN104740752A - Implantable intelligent in-vivo drug use control device - Google Patents

Implantable intelligent in-vivo drug use control device Download PDF

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Publication number
CN104740752A
CN104740752A CN201510164366.7A CN201510164366A CN104740752A CN 104740752 A CN104740752 A CN 104740752A CN 201510164366 A CN201510164366 A CN 201510164366A CN 104740752 A CN104740752 A CN 104740752A
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China
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medicine
singlechip
control system
electronic control
grug transportation
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CN201510164366.7A
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Chinese (zh)
Inventor
周容
罗林丽
龚云辉
代莉
贾瑾
白一
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West China Second University Hospital of Sichuan University
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West China Second University Hospital of Sichuan University
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Priority to CN201510164366.7A priority Critical patent/CN104740752A/en
Publication of CN104740752A publication Critical patent/CN104740752A/en
Pending legal-status Critical Current

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Abstract

The invention discloses an implantable intelligent in-vivo drug use control device. The implantable intelligent in-vivo drug use control device comprises at least one drug storage bag, a drug adding mechanism of which the number is the same with the number of the drug storage bag, a drug conveying pipe, a programmed switch, a loading plate, a drug infusion pump, a first electronic control system, a first power supply, a second electronic control system and a second power supply; the first power supply, the first electronic control system, the drug storage bag, the drug inlet section of the drug conveying pipe, the controlled section provided with the drug conveying pipe, the programmed switch and the loading plate of the drug infusion pump are encapsulated in at least one box body. When using, the implantable intelligent in-vivo drug use control device is embedded under the skin of a patient, the drug adding mechanism is embedded under the skin of the patient, and the drug outlet section of the drug conveying pipe is arranged in the abdominal cavity, chest, skull and muscle, under the skin or the like; the second electronic control system is located outside the patient body and used for sending a drug conveying command and receiving and displaying the drug conveying information.

Description

Implanted intelligent control volume innerlich anwenden device
Technical field
The invention belongs to medical apparatus and instruments, particularly a kind of for the device carrying out medication that implants.
Background technology
Along with the arrival of aging society, the Drug therapy of chronic disease and cancer has become the problem of the more and more sternness that medical domain faces, some patients may need the mode long-term prescription by vein or intramuscular injection, but no matter intramuscular injection or intravenous administration are for the risk both increasing repeated localised puncture patient lower for the resistance undoubtedly and cause wound and infection, patient need frequently hurry back and forth in medical institutions simultaneously, have a strong impact on daily life and the work of patient, too increase the working strength of medical worker.Slow release practical technique is the emerging application method of in recent years one, by operation in subcutaneous implantation slow releasing capsule, medicine by capsule wall be released slowly into subcutaneous absorbed by patient after play pharmacological action.This application method is particularly useful for the patient of chronic pain and hormone replacement therapy.But the dose held due to slow releasing capsule is limited, medicine can not continue after using up and add, and therefore this application method exists the restriction of service time while bringing convenience for patient, can not meet the needs of patient's life-time service.And, if needing to continue to use after slow releasing pharmaceutical is finished just needs again to perform the operation in patient body embedded set slow releasing capsule, add wound and the misery of patient.
Because slow release practical technique have employed the principle that medicine can spread under Concentraton gradient from high concentration to low concentration, the rate of release of medicine is constant, and medicine can only play a role at whole body after being discharged into subcutaneous absorption, thus can not meet the problem of the intelligentized control method to dosage and administration time, the needs of part disease topical therapy can not be met.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art, a kind of Implanted intelligent control volume innerlich anwenden device is provided, this kind of device not only can need to regulate dosage and administration time according to conditions of patients, and the object that can reach complementary medicine by simple operations after medicine is used up, extend patient's service time.
Implanted intelligent control volume innerlich anwenden device of the present invention, comprises at least one medicine storing bag, the medicating mechanism identical with medicine storing bag quantity, grug transportation tube, grammed switch, loading plate, killer injecting pump, the first electronic control system, the first power supply, the second electronic control system and second source; Described first electronic control system is made up of the first single-chip microcomputer and the first wireless receiver be connected with the first single-chip microcomputer respectively and the first wireless transmitter, first wireless transmitter is used for sending information to the second electronic control system, and the first wireless receiver is for receiving the information that comes from the second electronic control system and by the information transmission that receives to the first single-chip microcomputer; Described second electronic control system comprises second singlechip and the second wireless receiver be connected with second singlechip respectively, the second wireless transmitter, man-machine interactive operation button and display, second wireless transmitter is used for sending instruction to the first electronic control system, second wireless receiver is for receiving the information that comes from the first electronic control system and by the information transmission that receives to second singlechip, man-machine interactive operation button is used for sending instruction, the information that display receives for showing second singlechip to second singlechip; Described first power supply is used for providing operating current to the first electronic control system, grammed switch, and described second source is used for providing operating current to the second electronic control system; Described medicating mechanism by add medicine glass, with add chemical feed pipe that medicine glass is connected and the closure plate that medical elastic material makes forms, described closure plate covers and adds medicine glass rim of a cup for adding medicine glass after closed powder charge, described grug transportation tube is successively by entering medicine section, being formed by control section and drug section, described by control section be arranged on loading plate arrange groove in, medicine storing bag connects with the chemical feed pipe of corresponding medicating mechanism respectively and the medicine section of entering of grug transportation tube connects; Described grammed switch is connected with the first single-chip microcomputer and is arranged on installs grug transportation tube by the groove on the loading plate of control section, for conducting or block medicinal liquid and flow out the path of medicine storing bag and control the speed that flows out from medicine storing bag of medicine; Described killer injecting pump is connected with the first single-chip microcomputer and is arranged on loading plate, for driving the flowing of grug transportation tube inner liquid medicine; Described first single-chip microcomputer is according to the mode of operation parameter of the instruction of second singlechip adjustment grammed switch status and killer injecting pump (comprising velocity of rotation, injection amount, injection time, injection interval time etc.), and the information after adjustment is transferred to second singlechip by the first wireless transmitter, the second wireless receiver, according to instruction start or the shutdown of second singlechip; The information coming from the first single-chip microcomputer received is carried out processing and is transferred to display and shown by described second singlechip, is transferred to the first single-chip microcomputer after the instruction coming from man-machine interactive operation button being processed by the second wireless transmitter, the first wireless receiver; Entering medicine section and being provided with grug transportation tube of described first power supply, the first electronic control system, medicine storing bag, grug transportation tube is encapsulated at least one box body by the loading plate of control section and grammed switch.
Above-mentioned Implanted intelligent control volume innerlich anwenden device, the shape of grug transportation tube is main relevant with the number of medicine storing bag with structure: when medicine storing bag is one, grug transportation tube is bar shaped pipe, and medicine storing bag is connected with bar shaped pipe; When medicine storing bag is two, the preferred Y tube of grug transportation tube, two upper arm pipes of Y tube are connected with two medicine storing bags respectively; When medicine storing bag is more than three or three, the arm that grug transportation tube preferred amount is identical with medicine storing bag and the breeches pipe that is responsible for junction and forms, each arm of breeches pipe is connected with each medicine storing bag respectively.Grug transportation tube can be monolithic construction, also can be the grug transportation tube of split-type structural, described split-type structural, and it is entered medicine section, by control section and drug Duan Weisan section independently pipe fitting, is connected combine by connection tube.
Above-mentioned Implanted intelligent control volume innerlich anwenden device, grammed switch is made up of two electromagnetic assemblies, the moving contact that described electromagnetic assembly is made by shell, coil, block, back-moving spring and electric magnet forms, one end of shell is closed, one end open, and block is arranged on the inwall of closed termination of outer cover, and coil is arranged on the cylinder section inwall of shell, back-moving spring is arranged on the housing of coil, moving contact is connected with back-moving spring, and its one end is inserted in coil, and its other end is towards the opening of shell.The coil electricity size of current of grammed switch can determine that grammed switch inside produces magnetic force size, and then can affect the compression degree of back-moving spring, finally affects the folding condition of grammed switch.When the coil is not energized, grammed switch inside does not produce magnetic force, and the moving contact of grammed switch is in closed condition in spring force effect; When the coil is energized, grammed switch inside produces magnetic force, and moving contact Compress Spring under magneticaction of grammed switch is in full open state.
Consider from angle easy to use, in Implanted intelligent control volume innerlich anwenden device of the present invention, second singlechip, second source are arranged in a box body, second wireless receiver, the second wireless transmitter are arranged on outer wall or the inwall of described box body, and man-machine interactive operation button, display are arranged on the outer wall of described box body.
In order to expand the function of the second electronic control system, second singlechip is also provided with alarm lamp, alarm buzzer, data storage and data output interface, second source is connected with power supply indicator, and alarm lamp, alarm buzzer, data storage are connected with second singlechip respectively with data output interface; Described data storage and second singlechip, second source are arranged in same box body, and described alarm buzzer is arranged on outer wall or the inwall of described box body, and described data output interface, alarm lamp and power supply indicator are arranged on the outer wall of described box body.
Implanted intelligent control volume innerlich anwenden device of the present invention, its using method is as follows:
Need the drug section of grug transportation tube in flow controllable type body innerlich anwenden device of the present invention to be placed in abdominal cavity, thoracic cavity, intracranial, intramuscular or the position such as subcutaneous according to conditions of patients, by being equipped with the first single-chip microcomputer, the first power supply, the first wireless receiver, the first wireless transmitter, medicine storing bag, grug transportation tube enter medicine section and be embedded in patient by the box body of control section, grammed switch, killer injecting pump and loading plate and medicating mechanism subcutaneous, makes second singlechip and the second source that is connected with second singlechip and other device are positioned at outside patient body.
Implanted intelligent control volume innerlich anwenden device of the present invention, its operation principle is as follows:
Operator by medicating mechanism add medicine glass add in medicine storing bag in advance needs use medicine, and by medicine total amount, the information such as dosage, administration time, the medication interval time input second singlechip of single medication, parameter information is launched by the second wireless transmitter by second singlechip, the first wireless receiver is transferred to the first single-chip microcomputer after receiving.First single-chip microcomputer sends instruction according to the signal received to grammed switch and killer injecting pump, when instruction is injection, grammed switch is opened, killer injecting pump starts to rotate, medicine flows in patient body from medicine storing bag, the rotating speed of killer injecting pump determines rate of administration, and the rotating speed of killer injecting pump and rotation time determine dosage; After instruction task completes, grammed switch is closed, and killer injecting pump stops operating, and medicine stops flowing out from medicine storing bag.The information of this medication is transferred to second singlechip by the first wireless transmitter, the second wireless receiver by the first single-chip microcomputer.Second singlechip processes to the received signal, and the display be connected with second singlechip can demonstrate the information such as power supply status, mode of operation comprising single dosage, medication total amount, residual drug, the first single-chip microcomputer.Different according to the medicine storing bag quantity that implants, the display of the second box body also can show the important parameter information such as medication total amount, residual drug, administration time of each medicine storing bag transmitted by the first single-chip microcomputer.In safety, when the first single-chip microcomputer monitors abnormal information (as: killer injecting pump rotating speed is abnormal), realize reporting to the police by second singlechip, and by arranging controls such as the first chip microcontroller power-off, shutdown to second singlechip, ensure the safety used.
After the medicine in medicine storing bag is finished, syringe needle can be used to add medicine by medicating mechanism is continuous in medicine storing bag.
The present invention has following beneficial effect:
1, device of the present invention by advance by medicine storage in patient body, continue after within the long term, need to come intelligent management drug use situation according to conditions of patients, decrease the risk of misery that the medication of repeated localised puncture wound brings to patient and infection, decrease the inconvenience that traditional application method brings to patient simultaneously.
2, device of the present invention can realize the accurate control to dosage and administration time, ensure that the therapeutic effect of Patient drug.
3, device of the present invention is also by using multiple medicine storing bag mutually to arrange in pairs or groups delivering medicament, achieves the target of personalized medicine, meanwhile, by the continuous useful life adding the very big extension fixture of medicine.
4, device of the present invention can carry out Real-Time Monitoring and record to medication information, and is used for analyzing by statistical conversion by data output interface.
5, device of the present invention is easy to use, by the control arranging the duty that can realize grammed switch and killer injecting pump to second singlechip; When the first single-chip microcomputer monitors abnormal information (as: killer injecting pump rotating speed is abnormal), realize reporting to the police by second singlechip, and by arranging controls such as the first chip microcontroller power-off, shutdown to second singlechip, ensure the safety used.
6, by being equipped with the first single-chip microcomputer, the first power supply, the first wireless receiver, the first wireless transmitter, killer injecting pump, that grug transportation tube is embedded in patient by the box body of control section, grammed switch and loading plate and medicating mechanism is subcutaneous, thus electronic component, grug transportation tube all can be changed easily by control section, medicating mechanism.
Accompanying drawing explanation
Fig. 1 is the first electronic control system, the second electronic control system and a kind of structured flowchart by control device in Implanted intelligent control volume innerlich anwenden device of the present invention.
Fig. 2 is the first electronic control system, the second electronic control system and another structured flowchart by control device in Implanted intelligent control volume innerlich anwenden device of the present invention.
Fig. 3 is medicine storing bag when being one and medicating mechanism, grug transportation tube combination schematic diagram, wherein, the bar shaped pipe of (1) figure to be grug transportation tube be monolithic construction, the bar shaped pipe of (2) figure to be grug transportation tube be split-type structural.
Fig. 4 is medicine storing bag when being two and medicating mechanism, grug transportation tube combination schematic diagram, wherein, the Y tube of (1) figure to be grug transportation tube be monolithic construction, the Y tube of (2) figure to be grug transportation tube be split-type structural.
Fig. 5 is medicine storing bag when being three and medicating mechanism, grug transportation tube combination schematic diagram, wherein, the breeches pipe of (1) figure to be grug transportation tube be monolithic construction, the breeches pipe of (2) figure to be grug transportation tube be split-type structural.
Fig. 6 is the structural representation of loading plate, wherein, (1) it is bar shaped pipe that the loading plate in figure is applicable to grug transportation tube, (2) it is Y tube that the loading plate in figure is applicable to grug transportation tube, and it is three arms and a breeches pipe be responsible for junction and formed that the loading plate in (3) figure is applicable to grug transportation tube.
Fig. 7 is the structural representation of medicating mechanism, and wherein, (1) figure is the outline drawing of medicating mechanism, and (2) figure is the sectional view of medicating mechanism.
Fig. 8 is the structural representation of grammed switch, and wherein, the grammed switch in (1) figure is in closed condition, and the grammed switch in (2) figure is in complete opening.
Fig. 9 is a medicine storing bag and medicating mechanism, the assembly of grug transportation tube and grammed switch, the scheme of installation of killer injecting pump on loading plate, wherein, (1) grug transportation tube in figure is the bar shaped pipe of monolithic construction, and the grug transportation tube in (2) figure is the bar shaped pipe of split-type structural.
Figure 10 is two medicine storing bags and medicating mechanism, the assembly of grug transportation tube and grammed switch, the scheme of installation of killer injecting pump on loading plate, wherein, (1) grug transportation tube in figure is the Y tube of monolithic construction, use two secondary grammed switches, a killer injecting pump, (2) grug transportation tube in figure is the Y tube of monolithic construction, use a secondary grammed switch, two killer injecting pumps, (3) grug transportation tube in figure is the Y tube of split-type structural, use two secondary grammed switches, a killer injecting pump, (4) grug transportation tube in figure is the Y tube of split-type structural, use a secondary grammed switch, two killer injecting pumps.
Figure 11 is a kind of outline drawing of Implanted intelligent control volume innerlich anwenden device of the present invention, wherein, (1) figure is the outline drawing after being arranged on each Component composition in patient body, and (2) figure is the outline drawing after being positioned at each Component composition outside patient body.
Figure 12 is that Implanted intelligent control volume innerlich anwenden device of the present invention uses schematic diagram.
In figure, 1 medicating mechanism, 1-1 chemical feed pipe, 1-2 adds medicine glass, 1-3 closure plate, 2 medicine storing bags, 3 grug transportation tubes, 3-1 enters medicine section, and 3-2 is by control section, 3-3 drug section, 4 connection tubes, 5 loading plates, 6 grammed switches, 6-1 shell, 6-2 coil, 6-3 block, 6-4 moving contact, 6-5 back-moving spring, 7 killer injecting pumps, 8 first box bodys, 9 first wireless transmission/reception windows, 10 second box bodys, 11 man-machine interactive operation buttons, 12 display, 13 second wireless transmission/reception windows, 14 alarm lamps, 15 alarm buzzers, 16 power supply indicators, 17 patients.
Detailed description of the invention
Below in conjunction with accompanying drawing, Implanted intelligent control volume innerlich anwenden device of the present invention is described further in configuration aspects.
Embodiment 1
In the present embodiment, Implanted intelligent control volume innerlich anwenden device comprises a medicine storing bag 2, medicating mechanism 1, bar shaped grug transportation tube 3, grammed switch 6, killer injecting pump 7, loading plate 5, first electronic control system, the first power supply, the second electronic control system and second source.Described first electronic control system as shown in Figure 1, is made up of the first single-chip microcomputer and the first wireless receiver be connected with the first single-chip microcomputer respectively and the first wireless transmitter.Described second electronic control system as shown in Figure 1, is made up of second singlechip and the second wireless receiver be connected with second singlechip respectively, the second wireless transmitter, man-machine interactive operation button and display.First single-chip microcomputer and second singlechip all select model to be the single-chip microcomputer (American TI Company production) of MSP430F135, and the model of first, second wireless receiver and first, second wireless transmitter is nRF905 (production of Suzhou Tian Yi Electronic Science and Technology Co., Ltd.).Described grug transportation tube 3 is split-type structural, as shown in (2) figure in Fig. 3, successively by entering medicine section 3-1, being formed by control section 3-2 and drug section 3-3, enter medicine section 3-1, be three sections of independently pipe fittings by control section 3-2 and drug section 3-3, connected by connection tube 4 and combine.Described medicating mechanism 1 as shown in Figure 7, by add medicine glass 1-2, with add chemical feed pipe 1-1 that medicine glass is connected and closure plate 1-3 and form, closure plate covers and adds medicine glass rim of a cup for adding medicine glass after closed powder charge.Described grammed switch 6 as shown in Figure 8, be made up of two electromagnetic assemblies, the moving contact 6-4 that described electromagnetic assembly is made by shell 6-1, coil 6-2, block 6-3, back-moving spring 6-5 and electric magnet forms, one end of shell is closed, one end open, and block is arranged on the inwall of closed termination of outer cover, and coil is arranged on the cylinder section inwall of shell, back-moving spring is arranged on the housing of coil, moving contact is connected with back-moving spring, and its one end is inserted in coil, and its other end is towards the opening of shell.Described loading plate 5, as shown in (1) figure in Fig. 6, is provided with the bar-shaped trough matched with grug transportation tube 3.Described killer injecting pump 7 is made up of micromachine and the oval cam that is connected with micromachine power output shaft.
The compound mode of each component and device: as shown in (2) figure in Fig. 3, the top of medicine storing bag 2 is connected with the chemical feed pipe of medicating mechanism 1, the bottom of medicine storing bag 2 is connected with the medicine section 3-1 that enters of grug transportation tube; As shown in (2) figure in Fig. 9, in the assembly that medicine storing bag, medicating mechanism, grug transportation tube are formed, the part of its grug transportation tube enters medicine section, be arranged in the strip groove that loading plate 5 arranges by control section and part drug section; Grammed switch 6 is connected with the first single-chip microcomputer and is arranged on installs grug transportation tube by the groove on the loading plate of control section, the micro machine of killer injecting pump 7 is electrically connected with the first single-chip microcomputer and is arranged on loading plate 5, and its oval cam is arranged in installs grug transportation tube by the groove ((2) figure see Fig. 1 and Fig. 9) on the loading plate of control section); As shown in Figure 1, the first power supply is used for providing operating current to the first electronic control system, grammed switch, and second source is used for providing operating current to the second electronic control system.
Entering medicine section and being provided with grug transportation tube of described first power supply, the first single-chip microcomputer, medicine storing bag 2, grug transportation tube is encapsulated in the first box body 8 by the loading plate 5 of control section 3-2, grammed switch 6, first wireless receiver, the first wireless transmitter are arranged on the inwall of the first box body, described first box body 8 offers the first wireless transmission/reception window 9, and the drug section 3-3 of described medicating mechanism 1 and grug transportation tube is positioned at outside the first box body; Described second source, second singlechip are arranged in the second box body 10, second wireless receiver, the second wireless transmitter are arranged on the inwall of the second box body, described man-machine interactive operation button 11, display 12 are arranged on the outer wall of the second box body, and described second box body 10 offers the second wireless transmission/reception window 13.
In the present embodiment, Implanted intelligent control volume innerlich anwenden device mounting means in use as shown in figure 12, the drug section 3-3 of grug transportation tube is placed in the abdominal cavity of patient 17, thoracic cavity, intracranial, intramuscular or the position such as subcutaneous, it is subcutaneous that first box body 8 and medicating mechanism are embedded in patient, second box body 10 is positioned at outside patient body, by the hand-held operation of medical worker.
In the present embodiment, medicine storing bag 2, closure plate 1-3 medical grade rubber make, add medicine glass 1-2, chemical feed pipe 1-1 and the first box body 8 polyethylene to make, the entering medicine section 3-1, made by control section 3-2 and the soft polyvinyl chloride of drug section 3-3 of grug transportation tube 3, connection tube hard pvc makes.
Embodiment 2
In the present embodiment, flow controllable type body innerlich anwenden device difference from Example 1 is:
1, medicine storing bag 2 is two, medicating mechanism 1 is two, grug transportation tube 3 is Y tube, the top of two medicine storing bags 2 connects with the chemical feed pipe of corresponding medicating mechanism 1 respectively, and the bottom of two medicine storing bags 2 is connected with two upper arm of Y tube grug transportation tube 3 (as Suo Shi (2) figure in Fig. 4) respectively.
2, loading plate 5 is provided with the Y shape groove (as Suo Shi (2) figure in Fig. 6) matched with grug transportation tube 3.
3, in the assembly that medicine storing bag, medicating mechanism, grug transportation tube are formed, the part of its grug transportation tube enters medicine section, be arranged in the Y shape groove that loading plate 5 arranges by control section and part drug section; Grammed switch 6 is two pairs, be separately positioned on and grug transportation tube Y shape be installed by two grooves on the loading plate of control section, killer injecting pump 7 is one, is arranged on and installs grug transportation tube Y shape by the groove (as Suo Shi (3) figure in Figure 10) on the loading plate of control section.
4, the second electronic control system adds alarm lamp 14, alarm buzzer 15, data storage, data output interface, alarm lamp 14, alarm buzzer 15, data storage, data output interface are connected with second singlechip respectively, and second source is connected with power supply indicator 16 (as shown in Fig. 2, Figure 11).
The invention is not restricted to above-described embodiment, such as, medicine storing bag 2 can be more than three or three, and grug transportation tube 3 is the arm and a breeches pipe be responsible for junction and formed that quantity is identical with medicine storing bag, and grug transportation tube 3 can also be monolithic construction etc.

Claims (10)

1. an Implanted intelligent control volume innerlich anwenden device, is characterized in that comprising at least one medicine storing bag (2), the medicating mechanism identical with medicine storing bag quantity (1), grug transportation tube (3), grammed switch (6), loading plate (5), killer injecting pump (7), the first electronic control system, the first power supply, the second electronic control system and second source;
Described first electronic control system is made up of the first single-chip microcomputer and the first wireless receiver be connected with the first single-chip microcomputer respectively and the first wireless transmitter, first wireless transmitter is used for sending information to the second electronic control system, and the first wireless receiver is for receiving the information that comes from the second electronic control system and by the information transmission that receives to the first single-chip microcomputer; Described second electronic control system comprises second singlechip and the second wireless receiver be connected with second singlechip respectively, the second wireless transmitter, man-machine interactive operation button and display, second wireless transmitter is used for sending instruction to the first electronic control system, second wireless receiver is for receiving the information that comes from the first electronic control system and by the information transmission that receives to second singlechip, man-machine interactive operation button is used for sending instruction, the information that display receives for showing second singlechip to second singlechip;
Described first power supply is used for providing operating current to the first electronic control system, grammed switch, and described second source is used for providing operating current to the second electronic control system;
Described medicating mechanism (1) is by adding medicine glass (1-2), with add chemical feed pipe (1-1) that medicine glass is connected and the closure plate (1-3) that medical elastic material makes forms, described closure plate covers and adds medicine glass rim of a cup for adding medicine glass after closed powder charge, described grug transportation tube is successively by entering medicine section (3-1), by control section (3-2) and drug section (3-3) composition, described by control section (3-2) be arranged on loading plate arrange groove in, medicine storing bag connects with the chemical feed pipe (1-1) of corresponding medicating mechanism respectively and the medicine section (3-1) of entering of grug transportation tube connects,
Described grammed switch is connected with the first single-chip microcomputer and is arranged on installs grug transportation tube by the groove on the loading plate of control section, for conducting or block medicinal liquid and flow out the path of medicine storing bag and control the speed that flows out from medicine storing bag of medicine; Described killer injecting pump is connected with the first single-chip microcomputer and is arranged on loading plate, for driving the flowing of grug transportation tube inner liquid medicine;
The instruction adjustment grammed switch status of described first single-chip microcomputer according to second singlechip and the mode of operation parameter of killer injecting pump, and the information after adjustment is transferred to second singlechip by the first wireless transmitter, the second wireless receiver, according to instruction start or the shutdown of second singlechip;
The information coming from the first single-chip microcomputer received is carried out processing and is transferred to display and shown by described second singlechip, is transferred to the first single-chip microcomputer after the instruction coming from man-machine interactive operation button being processed by the second wireless transmitter, the first wireless receiver;
Entering medicine section and being provided with grug transportation tube of described first power supply, the first electronic control system, medicine storing bag, grug transportation tube is encapsulated at least one box body by the loading plate of control section and grammed switch.
2. Implanted intelligent control volume innerlich anwenden device according to claim 1, when it is characterized in that medicine storing bag (2) is one, grug transportation tube (3) is bar shaped pipe, and medicine storing bag is connected with bar shaped pipe; When medicine storing bag (2) is two, grug transportation tube (3) is Y tube, and two upper arm pipes of Y tube are connected with two medicine storing bags (2) respectively; When medicine storing bag (2) is more than three or three, grug transportation tube (3) is the quantity arm identical with medicine storing bag and a breeches pipe be responsible for junction and formed, and each arm of breeches pipe is connected with each medicine storing bag respectively.
3. Implanted intelligent control volume innerlich anwenden device according to claim 2, it is characterized in that grug transportation tube (3) is for monolithic construction or split-type structural, the grug transportation tube (3) of described split-type structural, it enters medicine section (3-1), be three sections of independently pipe fittings by control section (3-2) and drug section (3-3), connected by connection tube (4) and combine.
4. Implanted intelligent control volume innerlich anwenden device according to claim arbitrary in claims 1 to 3, it is characterized in that grammed switch (6) is made up of two electromagnetic assemblies, described electromagnetic assembly is by shell (6-1), coil (6-2), block (6-3), moving contact (6-4) composition that back-moving spring (6-5) and electric magnet make, one end of shell is closed, one end open, block is arranged on the inwall of closed termination of outer cover, coil is arranged on the cylinder section inwall of shell, back-moving spring is arranged on the housing of coil, moving contact is connected with back-moving spring, its one end is inserted in coil, its other end is towards the opening of shell.
5. Implanted intelligent control volume innerlich anwenden device according to claim arbitrary in claims 1 to 3, it is characterized in that described second electronic control system also comprises alarm lamp (14), alarm buzzer (15), data storage and data output interface, alarm lamp (14), alarm buzzer (15), data storage are connected with second singlechip respectively with data output interface, and described second source is connected with power supply indicator (16).
6. Implanted intelligent control volume innerlich anwenden device according to claim 4, it is characterized in that described second electronic control system also comprises alarm lamp (14), alarm buzzer (15), data storage and data output interface, alarm lamp (14), alarm buzzer (15), data storage are connected with second singlechip respectively with data output interface, and described second source is connected with power supply indicator (16).
7. Implanted intelligent control volume innerlich anwenden device according to claim arbitrary in claims 1 to 3, it is characterized in that described second singlechip, second source is arranged in a box body, described second wireless receiver, the second wireless transmitter are arranged on outer wall or the inwall of described box body, and described man-machine interactive operation button, display are arranged on the outer wall of described box body.
8. Implanted intelligent control volume innerlich anwenden device according to claim 4, it is characterized in that described second singlechip, second source is arranged in a box body, described second wireless receiver, the second wireless transmitter are arranged on outer wall or the inwall of described box body, and described man-machine interactive operation button, display are arranged on the outer wall of described box body.
9. Implanted intelligent control volume innerlich anwenden device according to claim 5, it is characterized in that described second singlechip, second source and data storage are arranged in a box body, described second wireless receiver, the second wireless transmitter and alarm buzzer are arranged on outer wall or the inwall of described box body, and described man-machine interactive operation button, display, data output interface, alarm lamp and power supply indicator are arranged on the outer wall of described box body.
10. Implanted intelligent control volume innerlich anwenden device according to claim 6, it is characterized in that described second singlechip, second source and data storage are arranged in a box body, described second wireless receiver, the second wireless transmitter and alarm buzzer are arranged on outer wall or the inwall of described box body, and described man-machine interactive operation button, display, data output interface, alarm lamp and power supply indicator are arranged on the outer wall of described box body.
CN201510164366.7A 2015-04-08 2015-04-08 Implantable intelligent in-vivo drug use control device Pending CN104740752A (en)

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WO2000066204A1 (en) * 1999-04-30 2000-11-09 University Of Southern California Implantable microbolus infusion pump
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CN102036710A (en) * 2008-06-20 2011-04-27 药物代谢动力公司 A magnetic breather pump and a method for treating a brain tumor using the same
US20120245565A1 (en) * 2011-03-21 2012-09-27 Pharmaco-Kinesis Corporation Method for delivering gene and cell therapy to a tumor or targeted site using an implanted metronomic biofeedback pump
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CN104334226A (en) * 2011-11-22 2015-02-04 因库博实验室有限责任公司 Implantable solid-liquig drug delivery apparatus, formulations, and methods of use
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1128957A (en) * 1993-08-11 1996-08-14 托马斯·J·贝里根 Implantable drug delivery means
CN1118701A (en) * 1995-04-28 1996-03-20 王建 Open type implanting pulse slow-releasing double-way artificial pancreas (pump)
WO2000066204A1 (en) * 1999-04-30 2000-11-09 University Of Southern California Implantable microbolus infusion pump
US20140088501A1 (en) * 2007-06-07 2014-03-27 The Alfred E. Mann Foundation For Scientific Research Implantable infusion devices including apparatus for confirming side port access
CN102036710A (en) * 2008-06-20 2011-04-27 药物代谢动力公司 A magnetic breather pump and a method for treating a brain tumor using the same
US20100274196A1 (en) * 2009-04-27 2010-10-28 Brandt William A Implantable infusion devices and associated methods
US20120245565A1 (en) * 2011-03-21 2012-09-27 Pharmaco-Kinesis Corporation Method for delivering gene and cell therapy to a tumor or targeted site using an implanted metronomic biofeedback pump
CN104334226A (en) * 2011-11-22 2015-02-04 因库博实验室有限责任公司 Implantable solid-liquig drug delivery apparatus, formulations, and methods of use
CN103800991A (en) * 2014-02-21 2014-05-21 四川大学华西医院 Device capable of automatically adjusting shunt volume of cerebrospinal fluid and preventing shunt tube from being blocked
CN204034040U (en) * 2014-08-25 2014-12-24 北京品驰医疗设备有限公司 A kind of low-power consumption Implanted medical system
CN104368059A (en) * 2014-11-18 2015-02-25 肖程午 Minimally invasive intervention implantable drug-supplying device with one-way valve
CN204723584U (en) * 2015-04-08 2015-10-28 四川大学华西第二医院 Implanted intelligent control volume innerlich anwenden device

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Application publication date: 20150701