CN104740748B - A kind of guiding catheter - Google Patents

A kind of guiding catheter Download PDF

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Publication number
CN104740748B
CN104740748B CN201310749764.6A CN201310749764A CN104740748B CN 104740748 B CN104740748 B CN 104740748B CN 201310749764 A CN201310749764 A CN 201310749764A CN 104740748 B CN104740748 B CN 104740748B
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CN
China
Prior art keywords
fluid
guiding catheter
chamber
inner tube
catheter according
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Application number
CN201310749764.6A
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Chinese (zh)
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CN104740748A (en
Inventor
黄慧华
张滢涛
金巧蓉
谢志永
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shentu medical technology (Shanghai) Co.,Ltd.
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Minimally Invasive Shentong Medical Technology (shanghai) Co Ltd
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Priority to CN201310749764.6A priority Critical patent/CN104740748B/en
Priority to PCT/CN2014/095936 priority patent/WO2015101333A1/en
Publication of CN104740748A publication Critical patent/CN104740748A/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • A61M25/0045Catheters; Hollow probes characterised by structural features multi-layered, e.g. coated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0021Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026Multi-lumen catheters with stationary elements
    • A61M25/0032Multi-lumen catheters with stationary elements characterized by at least one unconventionally shaped lumen, e.g. polygons, ellipsoids, wedges or shapes comprising concave and convex parts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • A61M25/005Catheters; Hollow probes characterised by structural features with embedded materials for reinforcement, e.g. wires, coils, braids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/06Body-piercing guide needles or the like
    • A61M25/0662Guide tubes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The present invention provides a kind of guiding catheter, is able to bear bigger negative pressure and has the lesser sacculus pumpback time.The guiding catheter includes outer tube, inner tube, fluid-through chamber and the sacculus being connected to the fluid-through chamber, one or more fluid-through chambers are distributed on the circumference of the outer tube wall thickness, and the section of the fluid-through chamber is greater than the distance of its radially farthest two o'clock in the distance of the conduit circumference farthest two o'clock upwards.

Description

A kind of guiding catheter
Technical field
The present invention relates to the field of medical instrument technology, a kind of particularly guiding catheter.
Background technique
Guiding catheter is a kind of sheath specially designed, can provide channel direction.It is usually used in conveying various interposers Tool arrival targets target, provides support and protection for it.Modern technologies rapid development, in order to meet clinical demand, various shape, The guiding catheter of various functions is developed, such as the guiding catheter with sacculus.
For balloon guide catheter, collapsed in addition to being required to bear certain negative pressure to avoid conduit, sacculus The flexibility of pumpback time and guiding catheter head end is also most important.Product on the market at present, since sacculus is in the mistake of pumpback Cheng Zhong, conduit collapse, and cause the sacculus pumpback time longer, increase the risk of thrombosis and distal vessels ischemic;By It is harder in conduit head end, it cannot be introduced into farther blood vessel, the failure for causing some brackets or embolism to be performed the operation.
Summary of the invention
In view of this, the present invention provides a kind of guiding catheter, biggish negative pressure can not only be born, and there is lesser ball Capsule pumpback time and soft head end.
To achieve the above object, the invention provides the following technical scheme:
A kind of guiding catheter, including outer tube, inner tube, fluid-through chamber and the sacculus being connected to the fluid-through chamber, one or more A fluid-through chamber is distributed on the circumference of the outer tube wall thickness, and the section of the fluid-through chamber is farthest upwards in the conduit circumference The distance of two o'clock is greater than the distance of its radially farthest two o'clock.
Optionally, it is overlapped or is bonded with the side in said inner tube section to the rim portion in the fluid-through chamber section.
Optionally, the shape in the fluid-through chamber section is crescent, ellipse, bone-shaped, cashew nut shape or kidney-shaped.
Optionally, smooth film is covered on the wall of the fluid-through chamber.
Optionally, said inner tube has three-decker, and wherein cladding material is polyurethane;Middle layer is wound by wire And/or braiding is made, the wire is one of following material or several combinations: stainless steel 304 V, Nitinol, Tungsten;Internal layer is one of poly- fluorocarbon, polyethylene, polypropylene or polyamide or a variety of copolymers.
Optionally, the material of the outer tube is one of following material or several combinations: polyamide, polyurethane, Buddhist nun Dragon, high density polyethylene (HDPE), block polyetheramides elastomer;And the hardness of the material of the outer tube proximally arrives distal end and becomes step by step It is small.
Optionally, the head end of the guiding catheter is constituted between the distal end of the sacculus and the distal end of the guiding catheter, The head end is formed by the internal layer of said inner tube and the extended segment of outer layer.
Optionally, the length of the head end is 3mm-100mm.
According to the technique and scheme of the present invention, guiding catheter is non-coaxial, wall of one or more fluid-through chambers in outer tube wall Form non-coaxial cavity in thickness, the size and shape of fluid-through chamber can according to the required Bulking Time and pumpback time of sacculus come Design.Three-decker possessed by the inner tube of this conduit and braiding therein and/or winding wire middle layer to lead The inner tube of pipe can participate in the support of conduit, improve the ability that conduit bears negative pressure.The shape in the section of fluid-through chamber can be use up Possibly using the space where the wall thickness of outer tube, to provide biggish flow, and the shadow of the ability of negative pressure is born to conduit Sound is smaller.
Detailed description of the invention
Attached drawing for a better understanding of the present invention, does not constitute an undue limitation on the present invention.Wherein:
Fig. 1 is the schematic diagram of the shape of guiding catheter according to an embodiment of the present invention;
Fig. 2 is the schematic diagram of the section of guiding catheter according to an embodiment of the present invention;
Fig. 3 A to Fig. 3 E is the schematic diagram of several optional patterns of the Section A-A of Fig. 2;
Fig. 4 and Fig. 5 is the schematic diagram of the structure of the spring of inner tube according to an embodiment of the present invention;
Fig. 6 is the schematic diagram of the head end structure of guiding catheter according to an embodiment of the present invention.
Specific embodiment
Below in conjunction with attached drawing, an exemplary embodiment of the present invention will be described, including the various of the embodiment of the present invention Details should think them only exemplary to help understanding.Therefore, those of ordinary skill in the art should recognize It arrives, it can be with various changes and modifications are made to the embodiments described herein, without departing from scope and spirit of the present invention.Together Sample, for clarity and conciseness, descriptions of well-known functions and structures are omitted from the following description.
Fig. 1 is into Fig. 7, each serial number mark are as follows: 1- connector, 2- delivery conduit body, the expansible sacculus of 3-, 4- diffusion are answered Solenoid, 5- fluid-through chamber, 6- lead-in cavity, 21- outer tube, 22- inner tube, 11- connector side port, 12- connector main aperture, 221- inner tube Outer layer, the middle layer of 222 inner tubes, the internal layer of 223- inner tube, the first spring ring of 2221-, 2222- second spring circle, the bonding pad 31- Domain, 32- join domain, 7- development point, 8- head end, 9- glue.
As shown in Figure 1, Figure 2 and shown in Fig. 6 A, Fig. 6 B, the guiding catheter in the embodiment of the present invention includes expandable balloon 3, conveying Catheter body 2, diffusion-induced stress pipe 4 and connector 1, the delivery conduit body 2 include outer tube 21, inner tube 22, fluid-through chamber 5 and lead-in cavity 6, wherein fluid-through chamber 5 is as made of inner surface low friction coefficient materials, and lead-in cavity 6 is made of the inner cavity of inner tube 22;It can expand The proximal end for opening sacculus 3 is connected with the distal seal of outer tube 21, and the distal end of expandable balloon 3 is connected with the distal seal of inner tube 22; Connector 1 is connected with the proximal end of delivery conduit body 2, and the proximal end of diffusion-induced stress pipe 4 is connected with the distal end of connector 1.Positioned at sacculus 3 Development point 7, development 7 accurate positionin for conduit in surgical procedure of point are embedded on the tube wall of the inner tube 22 at position.
With reference to Fig. 2, Fig. 3 A to Fig. 3 E, the guiding catheter in the present embodiment is non-coaxial, and fluid-through chamber 5 is located at outer tube 21 It in wall thickness, therefore is non-coaxial cavity with inner tube 22 and outer tube 21, the size and shape of fluid-through chamber 5 can be according to the institute of sacculus Bulking Time and pumpback time is needed to design.The fluid-through chamber of this non-coaxial enables the inner tube of conduit to participate in the branch of conduit Support improves the ability that conduit bears negative pressure.A part of the wall of fluid-through chamber 5 can be the outer wall of inner tube.On the wall of fluid-through chamber 5 It can also be covered with smooth film, the coefficient of friction of the wall of fluid-through chamber 5 can be reduced in this way, balloon expandable medium is avoided to adhere to too much Conduit withdraws difficulty caused by fluid-through chamber, facilitates the time for reducing sacculus pumpback, reduces thromboembolic complications With the risk of distal ischemia.
Fluid-through chamber can also be designed to other shapes, in order to keep Bulking Time and the pumpback time of sacculus short as much as possible, Fluid-through chamber need to be made to have flow as big as possible, but conduit integrally needs thinner outer diameter.Thus in the present embodiment, fluid-through chamber Section be greater than the distance of its radially farthest two o'clock in the distance of conduit circumference farthest two o'clock upwards, in Fig. 3 A to Fig. 3 E Shown in fluid-through chamber 51 to 55, as an example, showing the fluid-through chamber section (fluid-through chamber in such as Fig. 3 A, 3E in crescent in figure 51,55) and similar to bone-shaped fluid-through chamber section (fluid-through chamber 53 in such as Fig. 3 C).The section of fluid-through chamber is also possible to ellipse Circle, as shown in the fluid-through chamber 52 in Fig. 3 B.Fluid-through chamber can also be the shape similar to kidney;Shape can also be longer, i.e., Similar to the shape of cashew nut.These above-mentioned shapes can be as much as possible using the space where the wall thickness of outer tube 21, to mention For biggish flow, and the influence for bearing the ability of negative pressure to conduit is smaller.In addition fluid-through chamber is also possible to multiple, such as above-mentioned It is each as shown in the figure.
The wall of fluid-through chamber can be directly made of outer tube material;Or a portion is the outer wall of inner tube, leads to liquid at this time The wall of chamber is overlapped with the wall of inner tube.Fluid-through chamber also can have special wall, can be bonded or separate with the outer wall of inner tube, i.e., logical The material of the wall of sap cavity is different from outer tube and inner tube, and polytetrafluoroethylene (PTFE) (PTFE) can be used, be also possible to fluorinated ethylene propylene (FEP) (FEP)。
Fluid-through chamber 5 is communicated with the side opening 11 of connector 1, and expansion medium is injected in fluid-through chamber 5 by the side opening 11 of connector. Outer tube 22 is formed by the tubing of three sections of different hardness, and relative hardness distal shaft section, middle transition section and relatively soft are broadly divided into Distal shaft section that is soft and being connected to proximal part.Outer tube 22 can use following material: polyamide, polyurethane, nylon, high density Polyethylene or block polyetheramides elastomer (PEBAX) are composed, hardness 78D-20D.
As shown in Figure 4 and Figure 5, the inner tube 22 in the guiding catheter of the embodiment of the present invention includes internal layer 223,221 and of outer layer Middle layer 222 (spring ring reinforcement), in addition it can add development point 7.The internal layer 223 of inner tube is thicker than the outer layer 221 of inner tube It spends small or roughly the same;Wherein, the constituent material of internal layer 223 can are as follows: one of PTFE, FEP and high density polyethylene (HDPE), or Two kinds of person are composed, and improve the surface smoothness of lead-in cavity 6, to make seal wire, take bolt device etc. more smoothly to reach lesion Position.The internal diameter preferred value of inner tube 22 is 1.2mm-2.1mm.Wherein, the constituent material of outer layer 221 can are as follows: nylon, silicon rubber, One of polyurethane, polyamide series or block polyetheramides elastomer (PEBAX) or multiple combinations form, and hardness is 25D-55D.Wherein, middle layer 222 is made of two different wire spring circle wrapping wire direction differences, can be according to product Required intensity, the density of wrapping wire is arranged.The material of spring ring can be the metal materials such as stainless steel 304 v, Nitinol or tungsten Material, diameter can use circle silk or flat filament between 0.1mm-0.3mm.
The distal end of sacculus 3 can be connect with the distal end of inner tube 22 by adhesive seal, form join domain 32, this can be used as Head end, or have a distance from head end, as shown in fig. 6, conduit head end 8 is sacculus front end 81 (i.e. close to distal end of catheter 82 One end) and distal end of catheter 82 between part, formed by the internal layer 223 of inner tube 22 and the extended segment of outer layer 221.The length of head end 8 Degree are as follows: 3mm-100mm.
In addition, the overall surface of the guiding catheter of the embodiment of the present invention or at least sacculus 3 and 8 part of head end for example, by The methods of coating, injection form the coating being made of hydrophilic material, help to reduce mantle friction, conduit is made integrally to enter blood Pipe is more smooth when current, improves the operating characteristics of conduit.Above-mentioned hydrophilic coating material may is that polyvinylpyrrolidone (PVP), Sodium Hyaluronate, polyurethane etc..Several specific embodiments of the present invention are lifted below.
Embodiment 1
3 development points are used in the present embodiment, are separately positioned among head end and sacculus, and material is using silver.Outer tube material For PEBAX, the hardness for proximally arriving distal end becomes smaller step by step, respectively 78D, 55D, 35D.Three layers of establishment material that inner tube uses, Cladding material is polyurethane, and middle layer is formed by stainless steel wrap wire, silk wide 0.2mm, internal layer PTFE.Inner tube diameter is 3mm.It is logical The section of sap cavity 5 uses crescent.The header terminal design length of conduit is 3mm.After the completion of conduit integrated connection, catheter surface coating Hydrophilic coating, water wetted material are selected: Sodium Hyaluronate.
Embodiment 2
2 development points are used in the present embodiment, are separately positioned among head end and sacculus, and material uses platinumiridio.Outside Tube material is PEBAX, and the hardness for proximally arriving distal end becomes smaller step by step, respectively 72D, 63D, 40D.Inner tube uses three layers of establishment material Material, cladding material is polyurethane, and middle layer is formed by stainless steel wrap wire, silk wide 0.15mm, internal layer FEP.Inner tube diameter is 2mm, fluid-through chamber 54 use binary channels crescent.Conduit head end design length is 10mm.After the completion of conduit integrated connection, conduit table Face applies hydrophilic coating, and water wetted material selects polyvinylpyrrolidone (PVP).
Embodiment 3
Two development points are used in the present embodiment, are separately positioned among head end and sacculus, and material uses platinumiridio.Outside Tube material is PEBAX, and the hardness for proximally arriving distal end becomes smaller step by step, respectively 72D, 55D, 25D.Inner tube uses three layers of establishment material Material, cladding material PEBAX, middle layer are formed by Nitinol wrapping wire, the wide 0.15mm of silk, and internal layer is fluororesin (EFEP), interior Bore is 1mm.Fluid-through chamber 56 uses triple channel bone-shaped.Conduit head end design length is 15mm.Conduit integrated connection is completed Afterwards, catheter surface applies hydrophilic coating, and water wetted material selects polyurethane.
Technical solution according to an embodiment of the present invention, guiding catheter are non-coaxials, and one or more fluid-through chambers are in outer tube Non-coaxial cavity is formed in the wall thickness of wall, the size and shape of fluid-through chamber can be according to the required Bulking Time of sacculus and pumpback Time is designed.Three-decker possessed by the inner tube of this conduit and braiding therein and/or winding wire middle layer Enable the inner tube of conduit to participate in the support of conduit, improves the ability that conduit bears negative pressure.The shape in the section of fluid-through chamber To provide biggish flow, and the energy of negative pressure can be born to conduit as much as possible using the space where the wall thickness of outer tube The influence of power is smaller.
Above-mentioned specific embodiment, does not constitute a limitation on the scope of protection of the present invention.Those skilled in the art should be bright It is white, design requirement and other factors are depended on, various modifications, combination, sub-portfolio and substitution can occur.It is any Made modifications, equivalent substitutions and improvements etc. within the spirit and principles in the present invention, should be included in the scope of the present invention Within.

Claims (9)

1. a kind of guiding catheter, including outer tube, inner tube, fluid-through chamber and the sacculus being connected to the fluid-through chamber, which is characterized in that One or more fluid-through chambers are distributed on the circumference of the outer tube wall thickness, and the section of the fluid-through chamber is in the conduit circumference The distance of farthest two o'clock is greater than the distance of its radially farthest two o'clock upwards;
Said inner tube has three-decker, wherein the middle layer of said inner tube is wound and/or woven by wire and is made;
The head end of the guiding catheter is constituted between the distal end of the sacculus and the distal end of said inner tube, the head end is by described interior The internal layer of pipe and the extended segment of outer layer are formed.
2. guiding catheter according to claim 1, which is characterized in that the rim portion in the fluid-through chamber section with it is described interior The side of tube section is overlapped or fitting.
3. guiding catheter according to claim 1, which is characterized in that the shape in the fluid-through chamber section is crescent, ellipse Circle, bone-shaped, cashew nut shape or kidney-shaped.
4. guiding catheter according to claim 1, which is characterized in that be covered with smooth film on the wall of the fluid-through chamber.
5. guiding catheter according to any one of claim 1 to 4, which is characterized in that the cladding material of said inner tube is Polyurethane.
6. guiding catheter according to any one of claim 1 to 4, which is characterized in that the wire is following material One of or several combinations: stainless steel 304 V, Nitinol, tungsten.
7. guiding catheter according to any one of claim 1 to 4, which is characterized in that the internal layer of said inner tube is poly- carbon One of fluorine compounds, polyethylene, polypropylene or polyamide or a variety of copolymers.
8. guiding catheter according to any one of claim 1 to 4, which is characterized in that
The material of the outer tube is one of following material or several combinations: polyamide, polyurethane, nylon, high density are poly- Ethylene, block polyetheramides elastomer;And the hardness of the material of the outer tube proximally arrives distal end and becomes smaller step by step.
9. guiding catheter according to claim 1, which is characterized in that the length of the head end is 3mm-100mm.
CN201310749764.6A 2013-12-31 2013-12-31 A kind of guiding catheter Active CN104740748B (en)

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CN201310749764.6A CN104740748B (en) 2013-12-31 2013-12-31 A kind of guiding catheter
PCT/CN2014/095936 WO2015101333A1 (en) 2013-12-31 2014-12-31 Guide catheter

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CN201310749764.6A CN104740748B (en) 2013-12-31 2013-12-31 A kind of guiding catheter

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CN104740748B true CN104740748B (en) 2019-06-11

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CN105193498B (en) * 2015-09-18 2019-03-08 先健科技(深圳)有限公司 Ablation catheter apparatus
CN105476670B (en) * 2016-01-20 2017-10-13 中国人民解放军第三军医大学第二附属医院 A kind of adjustable sheath of caliber
CN106620997A (en) * 2017-01-04 2017-05-10 临沂市兴华医用器材有限公司 Double-layer combined anesthesia catheter
CN106725696B (en) * 2017-02-13 2019-07-19 中国医科大学附属盛京医院 It is a kind of for blocking the dual balloon catheter of common iliac blood flow
CN107648721A (en) * 2017-09-06 2018-02-02 南通伊诺精密塑胶导管有限公司 A kind of anti-folding guiding catheter of high flow capacity
CN114870201A (en) * 2021-02-05 2022-08-09 微创神通医疗科技(上海)有限公司 Pipe enhancement layer and pipe
CN114288528A (en) * 2021-12-31 2022-04-08 科睿驰(深圳)医疗科技发展有限公司 Balloon micro-catheter and preparation method thereof
CN114796809A (en) * 2022-03-30 2022-07-29 深圳市顺美医疗股份有限公司 Balloon guide catheter

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CN1630542A (en) * 2002-02-27 2005-06-22 株式会社钟化 Balloon catheter for tentative vaso-occlusion
CN202459776U (en) * 2012-03-01 2012-10-03 骆助林 Balloon dilating catheter for postoperative biliary drainage and cholangio-jejunal anastomotic stoma dilation
CN203139358U (en) * 2013-02-01 2013-08-21 广州医学院第二附属医院 Improved structure type double-cavity balloon catheter used for injecting foam hardening agent
CN203944003U (en) * 2013-12-31 2014-11-19 微创神通医疗科技(上海)有限公司 A kind of guiding catheter

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WO2015101333A1 (en) 2015-07-09

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