CN104740307A - Traditional Chinese medicine for treating heart diseases - Google Patents

Traditional Chinese medicine for treating heart diseases Download PDF

Info

Publication number
CN104740307A
CN104740307A CN201510196064.8A CN201510196064A CN104740307A CN 104740307 A CN104740307 A CN 104740307A CN 201510196064 A CN201510196064 A CN 201510196064A CN 104740307 A CN104740307 A CN 104740307A
Authority
CN
China
Prior art keywords
parts
radix
chinese medicine
rhizoma
poria
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510196064.8A
Other languages
Chinese (zh)
Inventor
李常明
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201510196064.8A priority Critical patent/CN104740307A/en
Publication of CN104740307A publication Critical patent/CN104740307A/en
Pending legal-status Critical Current

Links

Abstract

The invention relates to traditional Chinese medicine for treating heart diseases. The traditional Chinese medicine for treating the diseases consists of the following components in parts by mass: 2 to 6 parts of blackend swallowwort root, 4 to 6 parts of notopterygium root, 2 to 6 parts of prepared rehmannia root, 4 to 8 parts of calcined fossil, 4 to 8 parts of pangolin scales, 6 to 10 parts of dry rohdea japonica roth, 4 to 10 parts of poria cocos, 6 to 10 parts of donkey-hide gelatin, 4 to 10 parts of peach kernel, 6 to 10 parts of fourstamen stephania root, 4 to 8 parts of ligusticum wallichii, 8 to 12 parts of poria, 1 to 6 parts of pericarpium citri reticulatae and 8 to 12 parts of radix polygonati officinalis. The formula of the traditional Chinese medicine for treating the heart diseases can promote blood and qi circulation and strengthen the body resistance to eliminate pathogenic factors, has a good curative effect for the heart diseases by virtue of the cooperation of various active ingredients and is proved to be excellent in effect for clinical use. The application of the traditional Chinese medicine for treating the heart diseases for 70 patients in 4 years proves that the heart diseases can be effectively treated, and the effective rate can reach 91.4 percent.

Description

One treats cardiopathic Chinese medicine
Technical field
The present invention relates to one and treat cardiopathic Chinese medicine, belong to liver internal-medicine traditional Chinese medicine formula technique field.
Background technology
Heart disease is the more common blood circulation diseases of a class.Blood circulation is by the sanguimotor neuro humor organizational composition of heart, blood vessel and adjustment, blood circulation diseases, also referred to as cardiovascular diseases, comprises the disease of above-mentioned all histoorgans, in internal disease, belongs to commonly encountered diseases, wherein common with heart disease, the labour force of patient can be affected significantly.
Summary of the invention
One is the object of the present invention is to provide to treat cardiopathic Chinese medicine, to treat for heart disease better.
To achieve these goals, technical scheme of the present invention is as follows.
One treats cardiopathic Chinese medicine, is made up of the component of following mass fraction: Radix Cynanchi Atrati 2 ~ 6 parts, Rhizoma Et Radix Notopterygii 4 ~ 6 parts, Radix Rehmanniae Preparata 2 ~ 6 parts, Os Draconis (calcined) 4 ~ 8 parts, Squama Manis 4 ~ 8 parts, dry Radix et Rhizoma Rohdeae Japonicae 6 ~ 10 parts, 4 ~ 10 parts, Poria, 6 ~ 10 parts, Colla Corii Asini, 4 ~ 10 parts, Semen Persicae, Radix Stephaniae Tetrandrae 6 ~ 10 parts, Rhizoma Chuanxiong 4 ~ 8 parts, Poria 8 ~ 12 parts, Pericarpium Citri Reticulatae 2 ~ 6 parts, Rhizoma Polygonati Odorati 8 ~ 12 parts.
Further, the cardiopathic Chinese medicine of above-mentioned treatment, is made up of the component of following mass fraction: Radix Cynanchi Atrati 2 parts, Rhizoma Et Radix Notopterygii 4 parts, Radix Rehmanniae Preparata 2 parts, Os Draconis (calcined) 4 parts, Squama Manis 4 parts, dry Radix et Rhizoma Rohdeae Japonicae 6 parts, 4 parts, Poria, 6 parts, Colla Corii Asini, 4 parts, Semen Persicae, Radix Stephaniae Tetrandrae 6 parts, Rhizoma Chuanxiong 4 parts, Poria 8 parts, Pericarpium Citri Reticulatae 2 parts, Rhizoma Polygonati Odorati 8 parts.
Further, the cardiopathic Chinese medicine of above-mentioned treatment, is made up of the component of following mass fraction: Radix Cynanchi Atrati 4 parts, Rhizoma Et Radix Notopterygii 5 parts, Radix Rehmanniae Preparata 4 parts, Os Draconis (calcined) 6 parts, Squama Manis 6 parts, dry Radix et Rhizoma Rohdeae Japonicae 8 parts, 7 parts, Poria, 8 parts, Colla Corii Asini, 7 parts, Semen Persicae, Radix Stephaniae Tetrandrae 8 parts, Rhizoma Chuanxiong 6 parts, Poria 10 parts, Pericarpium Citri Reticulatae 4 parts, Rhizoma Polygonati Odorati 10 parts.
Further, the cardiopathic Chinese medicine of above-mentioned treatment, is made up of the component of following mass fraction: Radix Cynanchi Atrati 6 parts, Rhizoma Et Radix Notopterygii 6 parts, Radix Rehmanniae Preparata 6 parts, Os Draconis (calcined) 8 parts, Squama Manis 8 parts, dry Radix et Rhizoma Rohdeae Japonicae 10 parts, 10 parts, Poria, 10 parts, Colla Corii Asini, 10 parts, Semen Persicae, Radix Stephaniae Tetrandrae 10 parts, Rhizoma Chuanxiong 8 parts, Poria 12 parts, Pericarpium Citri Reticulatae 6 parts, Rhizoma Polygonati Odorati 12 parts.
Herbal pharmacology and the effect of above-mentioned each component are as follows:
(1) Radix Cynanchi Atrati: bitter in the mouth, salty, cold in nature.Enter stomach, Liver Channel.Heat clearing away, removing heat from blood.Control yin asthenia generating intrinsic heat, the scorching hot hypersomnia of pathogenic wind-warm, lung-heat hemoptysis, pyrexial malaria, intermittent high fever, puerperal fidgets due to deficiency syncope due to excessive bleeding, pyretic stranguria, stranguria with blood, rheumatalgia, scrofula.
(2) Rhizoma Et Radix Notopterygii: loose exterior cold, wind-damp dispelling, sharp joint.Cure cold wind and cold, has a headache lossless, anemofrigid-damp arthralgia, stiffness of the nape muscular contracture, joint ache, edema due to wind pathogen edema, skin sore.
(3) Radix Rehmanniae Preparata: sweet in the mouth, slightly warm in nature.Return liver, kidney channel.Nourishing YIN and supplementing blood, beneficial essence fills out marrow.For the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat is passed out semen, and interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, and metrostaxis is dizzy, tinnitus, early whitening of beard and hair.
(4) Os Draconis (calcined): sweet-puckery flavor, property is put down.Enter the heart, liver, kidney, large intestine channel.Tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing.Control infantile convulsion demented, palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous sweating, and seminal emission stranguria with turbid discharge, tell nosebleed and have blood in stool, bleeding not during menses, dysentery proctoptosis, ulcer does not close up for a long time.
(5) Squama Manis: salty in the mouth, cold nature.Return liver, stomach warp.Blood circulation promoting and dispersing pathogen accumulation; To stimulate the menstrual flow stimulating milk secretion; Eliminating carbuncle is burst hard.Main blood stasis amenorrhea; Lump in the abdomen; Rheumatic arthralgia; Agalactia; Carbuncle; Scrofula.
(6) dry Radix et Rhizoma Rohdeae Japonicae: sweet-bitter flavor, cold in nature.Enter lung meridian.Heart tonifying diuresis, heat-clearing and toxic substances removing, hemostasis.Control heart failure, laryngopharynx swelling and pain, diphtheria, edema, tympanites, spitting of blood, spit blood, furuncle, erysipelas, Serpentis stings, and scalds.
(7) Poria: sweet in the mouth, light, property are put down.Energy eliminating dampness and diuresis; Invigorating the spleen and regulating the stomach; Mind tranquilizing and the heart calming.Cure mainly dysuria; Edema distension; Phlegm retention cough with dyspnea; Vomiting; Insufficiency of the spleen lack of appetite; Have loose bowels; Palpitation and restlessness; Insomnia forgetfulness; Seminal emission nebulousurine.
(8) Colla Corii Asini: sweet in the mouth, property is put down.Return lung, liver, kidney channel.Enrich blood, hemostasis, nourshing Yin and drynsessmoistening prescription.Spit blood for blood deficiency and yellow complexion, dizzy cardiopalmus, unable, the vexed insomnia of flesh flaccidity, stirring-up of pathogenic wind in the interior resulting from deficiency, xeropulmonary cough, phthisical cough, spit blood, metrorrhagia etc. of having blood in stool.
(9) Semen Persicae: property is put down, sweet-bitter flavor.Enter lung, liver, large intestine channel.There is blood stasis removing and clots absorbing, moisturize effect of laxation; Control amenorrhea , mass in the abdomen, calentura blood-retention, migratory arthralgia, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.
(10) Radix Stephaniae Tetrandrae: cold in nature, bitter in the mouth, pungent.Return bladder, kidney, spleen channel.There is effect of inducing diuresis to remove edema, wind-expelling pain-stopping.Harness the river swollen tympanites, hygropyretic beriberi, brothers' spasm and pain, tinea scabies swell.
(11) Rhizoma Chuanxiong: acrid in the mouth, warm in nature; Return liver, gallbladder, heart channel.There is blood-activating and qi-promoting, effect of wind-expelling pain-stopping.Cure mainly menoxenia, dysmenorrhea, amenorrhea, difficult labour, retention of placenta, lochia is suffered from abdominal pain, lump, heart pain in chest and hypochondrium, and traumatic injury swells and ache, headache vertigo and head dark, anemofrigid-damp arthralgia, numb limbs and tense tendons, ulcer sores.
(12) Poria: property is flat, sweet in the mouth and, avirulence.GUIXIN, lung, spleen channel.Benefiting vital QI for tranquillizing, invigorating the spleen and regulating the stomach, dispels damp and hot, row water stopping leak, the disease such as treatment deficiency of vital energy impairment caused by overstrain, trusted subordinate's distension, edema, diarrhoea, forgetful, insomnia.
(13) Pericarpium Citri Reticulatae: warm in nature; Acrid in the mouth, hardship; Return spleen, lung meridian.There is invigorating the spleen and regulating the stomach, promoting the circulation of QI to alleviate the stagnation in middle-JIAO, effect of lowering the adverse-rising QI and eliminating phlegm.Cure mainly stagnation of QI in spleen and stomach, gastral cavity abdomen covers with, nausea and vomiting, inappetence, cough with copious phlegm, and chest and diaphragm is full vexed, globus hystericus.
(14) Rhizoma Polygonati Odorati: sweet in the mouth, cold nature.Enter lung, stomach warp.There is yin nourishing, moisturize, relieving restlessness, the effect of quenching the thirst.Control consumption of YIN caused by febrile disease, cough excessive thirst, deficient fever, rapid digestion of food easily famine, frequent micturition etc.
Originally can blood-activating and qi-promoting, righting method is evil, and all medicines coordinate, and have better therapeutic effect to heart disease, clinical use often receive good effect.In 4 years, by showing the use of 70 patients, this medicine effectively can treat heart disease, and effective percentage reaches 91.4%.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data: inventor have collected 140 routine cardiacs between in March ,-2015 in March, 2011 altogether, wherein, 20 years old ~ 50 years old age, the state of an illness half a year ~ 3 years.Be divided at random: treatment group 70 example, matched group 70 example.The data there was no significant differences such as two groups of ages, have comparability.
2, test method: (1) matched group takes heart-nourishing pill, takes to specifications.30 days courses for the treatment of.(2) the oral the present invention for the treatment of group is according to the obtained powder of specific embodiment 2, early, middle and late each once.30 days courses for the treatment of.(3) criterion of therapeutical effect and therapeutic outcome: criterion of therapeutical effect: recovery from illness: cardiopathic clinical symptoms all disappears.Take a turn for the better: cardiopathic clinical symptom relief, the state of an illness is controlled.Invalid: cardiopathic clinical symptoms is without being clearly better or increasing the weight of.With recovery from illness and the calculating effective percentage that takes a turn for the better.Treatment statistical result is in table 1.
Table 1 liang group comparitive study
As can be seen here, the medicine adopting prescription of the present invention obtained can safe and effective treatment heart disease.
Detailed description of the invention
Below in conjunction with embodiment, the specific embodiment of the present invention is described, better to understand the present invention.
embodiment 1
The cardiopathic Chinese medicine for the treatment of in the present embodiment, takes Radix Cynanchi Atrati 2 grams, Rhizoma Et Radix Notopterygii 4 grams, Radix Rehmanniae Preparata 2 grams, Os Draconis (calcined) 4 grams, Squama Manis 4 grams, dry Radix et Rhizoma Rohdeae Japonicae 6 grams, 4 grams, Poria, 6 grams, Colla Corii Asini, 4 grams, Semen Persicae, Radix Stephaniae Tetrandrae 6 grams, Rhizoma Chuanxiong 4 grams, Poria 8 grams, Pericarpium Citri Reticulatae 2 grams, Rhizoma Polygonati Odorati 8 grams.Add 6 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, mix homogeneously, incapsulates shell, must meet the capsule for the treatment of 1 day consumption.Be used for the treatment of heart disease, oral, every bu is taken for early, middle and late three times.
embodiment 2
The cardiopathic Chinese medicine for the treatment of in the present embodiment, takes Radix Cynanchi Atrati 4 grams, Rhizoma Et Radix Notopterygii 5 grams, Radix Rehmanniae Preparata 4 grams, Os Draconis (calcined) 6 grams, Squama Manis 6 grams, dry Radix et Rhizoma Rohdeae Japonicae 8 grams, 7 grams, Poria, 8 grams, Colla Corii Asini, 7 grams, Semen Persicae, Radix Stephaniae Tetrandrae 8 grams, Rhizoma Chuanxiong 6 grams, Poria 10 grams, Pericarpium Citri Reticulatae 4 grams, Rhizoma Polygonati Odorati 10 grams.Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, close evenly, packaging, the powder for the treatment of 1 day consumption must be met.Be used for the treatment of heart disease, oral, every bu is taken for early, middle and late three times.
embodiment 3
The cardiopathic Chinese medicine for the treatment of in the present embodiment, takes Radix Cynanchi Atrati 6 grams, Rhizoma Et Radix Notopterygii 6 grams, Radix Rehmanniae Preparata 6 grams, Os Draconis (calcined) 8 grams, Squama Manis 8 grams, dry Radix et Rhizoma Rohdeae Japonicae 10 grams, 10 grams, Poria, 10 grams, Colla Corii Asini, 10 grams, Semen Persicae, Radix Stephaniae Tetrandrae 10 grams, Rhizoma Chuanxiong 8 grams, Poria 12 grams, Pericarpium Citri Reticulatae 6 grams, Rhizoma Polygonati Odorati 12 grams.Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, mix homogeneously, granulates according to this area common process, and packaging must meet the granule for the treatment of 1 day consumption.Be used for the treatment of heart disease, oral, every bu is taken for early, middle and late three times.
The above is the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention; can also make some improvements and modifications, these improvements and modifications are also considered as protection scope of the present invention.

Claims (4)

1. treat a cardiopathic Chinese medicine, it is characterized in that: be made up of the component of following mass fraction: Radix Cynanchi Atrati 2 ~ 6 parts, Rhizoma Et Radix Notopterygii 4 ~ 6 parts, Radix Rehmanniae Preparata 2 ~ 6 parts, Os Draconis (calcined) 4 ~ 8 parts, Squama Manis 4 ~ 8 parts, dry Radix et Rhizoma Rohdeae Japonicae 6 ~ 10 parts, 4 ~ 10 parts, Poria, 6 ~ 10 parts, Colla Corii Asini, 4 ~ 10 parts, Semen Persicae, Radix Stephaniae Tetrandrae 6 ~ 10 parts, Rhizoma Chuanxiong 4 ~ 8 parts, Poria 8 ~ 12 parts, Pericarpium Citri Reticulatae 2 ~ 6 parts, Rhizoma Polygonati Odorati 8 ~ 12 parts.
2. the cardiopathic Chinese medicine for the treatment of according to claim 1, is characterized in that: described Chinese medicine is made up of the component of following mass fraction: Radix Cynanchi Atrati 2 parts, Rhizoma Et Radix Notopterygii 4 parts, Radix Rehmanniae Preparata 2 parts, Os Draconis (calcined) 4 parts, Squama Manis 4 parts, dry Radix et Rhizoma Rohdeae Japonicae 6 parts, 4 parts, Poria, 6 parts, Colla Corii Asini, 4 parts, Semen Persicae, Radix Stephaniae Tetrandrae 6 parts, Rhizoma Chuanxiong 4 parts, Poria 8 parts, Pericarpium Citri Reticulatae 2 parts, Rhizoma Polygonati Odorati 8 parts.
3. the cardiopathic Chinese medicine for the treatment of according to claim 1, is characterized in that: described Chinese medicine is made up of the component of following mass fraction: Radix Cynanchi Atrati 4 parts, Rhizoma Et Radix Notopterygii 5 parts, Radix Rehmanniae Preparata 4 parts, Os Draconis (calcined) 6 parts, Squama Manis 6 parts, dry Radix et Rhizoma Rohdeae Japonicae 8 parts, 7 parts, Poria, 8 parts, Colla Corii Asini, 7 parts, Semen Persicae, Radix Stephaniae Tetrandrae 8 parts, Rhizoma Chuanxiong 6 parts, Poria 10 parts, Pericarpium Citri Reticulatae 4 parts, Rhizoma Polygonati Odorati 10 parts.
4. the cardiopathic Chinese medicine for the treatment of according to claim 1, is characterized in that: described Chinese medicine is made up of the component of following mass fraction: Radix Cynanchi Atrati 6 parts, Rhizoma Et Radix Notopterygii 6 parts, Radix Rehmanniae Preparata 6 parts, Os Draconis (calcined) 8 parts, Squama Manis 8 parts, dry Radix et Rhizoma Rohdeae Japonicae 10 parts, 10 parts, Poria, 10 parts, Colla Corii Asini, 10 parts, Semen Persicae, Radix Stephaniae Tetrandrae 10 parts, Rhizoma Chuanxiong 8 parts, Poria 12 parts, Pericarpium Citri Reticulatae 6 parts, Rhizoma Polygonati Odorati 12 parts.
CN201510196064.8A 2015-04-23 2015-04-23 Traditional Chinese medicine for treating heart diseases Pending CN104740307A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510196064.8A CN104740307A (en) 2015-04-23 2015-04-23 Traditional Chinese medicine for treating heart diseases

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510196064.8A CN104740307A (en) 2015-04-23 2015-04-23 Traditional Chinese medicine for treating heart diseases

Publications (1)

Publication Number Publication Date
CN104740307A true CN104740307A (en) 2015-07-01

Family

ID=53580927

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510196064.8A Pending CN104740307A (en) 2015-04-23 2015-04-23 Traditional Chinese medicine for treating heart diseases

Country Status (1)

Country Link
CN (1) CN104740307A (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005225847A (en) * 2004-02-16 2005-08-25 Pokka Corp Hypocholesterolemic agent, neutral fat lowering agent and phospholipid lowering agent
CN1765390A (en) * 2005-10-09 2006-05-03 孙永权 Chinese medicine for treating pulmonary heart disease

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005225847A (en) * 2004-02-16 2005-08-25 Pokka Corp Hypocholesterolemic agent, neutral fat lowering agent and phospholipid lowering agent
CN1765390A (en) * 2005-10-09 2006-05-03 孙永权 Chinese medicine for treating pulmonary heart disease

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
郭爱廷: "《实用单方验方大全》", 31 July 2011, 北京科学技术出版社 *

Similar Documents

Publication Publication Date Title
CN104001124A (en) Traditional Chinese medicinal composition for treating chronic gastritis
CN105535471A (en) Pill medicine for treating panasthenia and preparation method thereof
CN104027585A (en) Traditional Chinese medicine decoction for treating functional uterine bleeding
CN104758794A (en) Traditional Chinese medicine for treating nerve headache
CN103690900B (en) A kind of Chinese medicine for the treatment of dysfunctional uterine hemorrhage
CN103520571B (en) Traditional Chinese medicine for treating qi stagnation and blood stasis syndrome type abdominal mass diseases
CN106310150A (en) Chinese medicinal prescription for treatment of headache
CN104740481A (en) Traditional Chinese medicine for treating functional uterine bleeding
CN104547553A (en) Traditional Chinese medicine for treating nervous endocrine disorder
CN104173775A (en) Traditional Chinese medicine composition for treating cervicogenic headache and preparation method of traditional Chinese medicine composition
CN104055993A (en) Traditional Chinese medicine wine for external use for treating acute sprain
CN103520672B (en) The Chinese medicine for the treatment of dampness-heat of the liver pattern of syndrome menopathy
CN103656199B (en) A kind of Chinese medicine for the treatment of deficiency of kidney yin syndrome cough
CN103263575A (en) Medicine for treating headache and preparation method thereof
CN103656220B (en) A kind of Chinese medicine for the treatment of yang deficiency of spleen and stomache chronic enteritis
CN103536892B (en) Traditional Chinese medicine for treating infertility of syndrome of yang deficiency and coagulated cold
CN104740307A (en) Traditional Chinese medicine for treating heart diseases
CN101112517A (en) Chinese traditional medicine compounding for treating diabetic cardiac disease
CN101085316A (en) Traditional Chinese medicine preparation for treating menstrual vertigo
CN104740364A (en) Traditional Chinese medicine for treating dizziness diseases caused by hyperactivity of liver-yang
CN104645210A (en) Traditional Chinese medicine for improving digestion
CN104922409A (en) Traditional Chinese medicine for treating chronic cervicitis
CN103505713B (en) Traditional Chinese medicine formula for treating disharmony between ying and wei syndrome muscle numbness disease
CN103830392B (en) A kind of reducing swelling and alleviating pain medicine and preparation method
CN103536853B (en) The Chinese medicine for the treatment of deficiency of both the heart and spleen pattern of syndrome spleen fatiguing disease

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20150701