CN104707055A - Medicament for treating lithiasis in urinary system and preparation method thereof - Google Patents

Medicament for treating lithiasis in urinary system and preparation method thereof Download PDF

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CN104707055A
CN104707055A CN201510163942.6A CN201510163942A CN104707055A CN 104707055 A CN104707055 A CN 104707055A CN 201510163942 A CN201510163942 A CN 201510163942A CN 104707055 A CN104707055 A CN 104707055A
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张�杰
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Abstract

The invention discloses a medicament for treating lithiasis in urinary system, and the medicament is mainly prepared from the following raw materials in parts by mass: 8-12 parts of pink herb, 7-15 parts of poria skin, 7-16 parts of madder root, 9-15 parts of rhizoma anemarrhenae, 6-9 parts of lepisorus ussuriensis, 6-9 parts of crinis carbonisatus, 8-14 parts of bryozoatum, 8-16 parts of peruvian groundcherry herb, 4-9 parts of raw oyster shell, 4-9 parts of amber (taken after being mixed with water), 10-20 parts of radix platycodi, 10-20 parts of polygonum aviculare, 8-16 parts of yam rhizome, 9-15 parts of rhizoma phragmitis, 9-14 parts of semen lepidii, 6-9 parts of radix stemonae, 10-20 parts of bamboo shavings and 10-20 parts of fructus psoraleae. The medicament is a conclusion of clinical practice of many years, has the efficacies of clearing away heat and toxic materials and inducing diuresis for treating stranguria, has a remarkable curative effect and can be used for treating symptoms and causes.

Description

A kind of medicament and preparation method for the treatment of urinary system calculus
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of medicament and preparation method for the treatment of urinary system calculus.
Background technology
Urinary calculi is the commonly encountered diseases of urinary system.Calculus is found in any position of kidney, bladder, ureter and urethra.But be common with kidney and ureteral calculus.Clinical manifestation has different because position, calculus place is different.The typical performance of kidney and ureteral calculus is renal colic and hematuria, before calculus causes angor to show effect, patient is without any sensation, due to certain inducement, as strenuous exercise, work, long-distancely to ride, suddenly there is the angor that side waist is violent, and to lower abdomen and perineal position radiation, with abdominal distention, Nausea and vomiting, hematuria that degree is different; Vesical calculus main manifestations is dysuria and urodynamic.Western medicine many employings rubble method is treated, and this method not only costly, still needs medicine calculus after rubble, and the process of rubble easily injures internal organs, brings a lot of miseries and psychological burden to patient.
Publication No. CN 102872280 A(application number 201210346422.5) Chinese patent literature disclose a kind of Chinese medicine preparation for the treatment of urinary system calculus, calculate by weight, formula comprises: Herba Lysimachiae 30-50 part, Spora Lygodii 20-40 part, Folium Pyrrosiae 12-20 part, Herba Plantaginis 20-40 part, Talcum 25-45 part, Herba Artemisiae Scopariae 20-40 part, Herba Dianthi 10-20 part, Polyporus 10-15 part, Rhizoma Alismatis 10-15 part, Radix Paeoniae Rubra 15-20 part, raw Asteriscus Pseudosciaenae 15-20 part, succinum 2-3 part, Endothelium Corneum Gigeriae Galli 10-18 part, Fructus Cannabis 20-40 part.Publication No. CN 102205009 A(application number 201110136328.2) Chinese patent literature disclose a kind of Chinese medicine for the treatment of urinary system calculus, this Chinese medicine is made up of the crude drug of following weight: Endothelium Corneum Gigeriae Galli 30 grams, Spora Lygodii 15 grams, mole cricket 30 grams, Herba Lysimachiae 20 grams, Radix Cudraniae 30 grams, Semen Pittospori Glabrati 20 grams, Radix Scutellariae 15 grams, Herba Dianthi 20 grams, Semen Abutili 20 grams, Polyporus 20 grams, Rhizoma Alismatis 20 grams, Cortex Phellodendri 15 grams, said medicine solarization dry powder poling fine powder.Publication No. CN 104069441 A(application number 201410338852.1) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of urinary system calculus, described Chinese medicine composition comprises Herba Lysimachiae, Herba Polygoni Avicularis, Radix Curcumae, Semen Abutili, Lignum Aquilariae Resinatum, Endothelium Corneum Gigeriae Galli, Semen Persicae, Rhizoma Curcumae, Asteriscus Pseudosciaenae, Rhizoma Polygoni Cuspidati, Radix Cyathulae, Talcum 12 Chinese medicines.
Compared to the shortcoming of western medical treatment, treatment by Chinese herbs is more safe and effective, but the curative effect of some medicine awaits in further raising, therefore needs to develop the Chinese medicine formula that therapeutic effect is good, relapse rate is low.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, take wide a kind of medicament and the preparation method for the treatment of urinary system calculus of safe and applicable.
Technical scheme of the present invention is:
Treat a medicament for urinary system calculus, be prepared from primarily of following bulk drugs, be mass parts: Herba Dianthi 8-12; Cortex Sclerotii Poriae 7-15; Radix Rubiae 7-16; Rhizoma Anemarrhenae 9-15; Herba Lepisori Thunbergiani 6-9 in Usu; Crinis Carbonisatus 6-9; Pumex 8-14; Fructus Seu Herba Pubescentis 8-16; Concha Ostreae 4-9; Succinum (taking after mixing it with water) 4-9; Radix Platycodonis 10-20; Herba Polygoni Avicularis 10-20; Rhizoma Dioscoreae Septemlobae 8-16; Rhizoma Phragmitis 9-15; Semen Lepidii (Semen Descurainiae) 9-14; Radix Stemonae 6-9; Caulis Bambusae In Taenia 10-20; Fructus Psoraleae 10-20.
Preferred version is, Herba Dianthi 9-11; Cortex Sclerotii Poriae 9-13; Radix Rubiae 9-14; Rhizoma Anemarrhenae 11-13; Herba Lepisori Thunbergiani 7-8 in Usu; Crinis Carbonisatus 7-8; Pumex 10-12; Fructus Seu Herba Pubescentis 10-14; Concha Ostreae 5-8; Succinum (taking after mixing it with water) 5-8; Radix Platycodonis 12-18; Herba Polygoni Avicularis 12-18; Rhizoma Dioscoreae Septemlobae 10-14; Rhizoma Phragmitis 11-13; Semen Lepidii (Semen Descurainiae) 10-13; Radix Stemonae 7-8; Caulis Bambusae In Taenia 12-18; Fructus Psoraleae 12-18.
What be more preferably is, Herba Dianthi 10; Cortex Sclerotii Poriae 11; Radix Rubiae 11.5; The Rhizoma Anemarrhenae 12; Herba Lepisori Thunbergiani 7.5 in Usu; Crinis Carbonisatus 7.5; Pumex 11; Fructus Seu Herba Pubescentis 12; Concha Ostreae 6.5; Succinum (taking after mixing it with water) 6.5; Radix Platycodonis 15; Herba Polygoni Avicularis 15; Rhizoma Dioscoreae Septemlobae 12; Rhizoma Phragmitis 12; Semen Lepidii (Semen Descurainiae) 11.5; The Radix Stemonae 7.5; Caulis Bambusae In Taenia 15; Fructus Psoraleae 15.
Described a kind of medicament for the treatment of urinary system calculus, be made into pharmaceutically acceptable decoction, preparation method is:
(1) get Cortex Sclerotii Poriae, clear water is cleaned, and be cut into small pieces, put into frying pan, slow fire stir-fries burned black to surface, Guan Huohou, adds rice vinegar and mixes thoroughly, and moistening 10-20 minute (preferred: moistening 12-18 minute; Be more preferably: moistening 15 minutes), take out, dry and pulverize together with Crinis Carbonisatus;
(2) get Pumex and Concha Ostreae removing impurity, clean, be ground into broken end, put into marmite, add vinegar water soaking 20 minutes, big fire is heated to boiling, turns little fire and decocts, medicinal residues are added water and continue decoction 30 minutes by filtering and collecting filter liquid, mixing twice gained filtrate after filtering;
(3) get Semen Lepidii (Semen Descurainiae) and clean impurity picked up by Fructus Psoraleae, clean with Chinese liquor rubbing, after drying, put into parch container, add crude salt, slow fire heats, constantly stir-fry 15-25 minute (preferred: constantly stir-fry 18-22 minute; Be more preferably: constantly stir-fry 20 minutes), take out, sieve and remove crude salt, pulverized 160 mesh sieves together with step (1) made crude drug;
(4) Radix Rubiae, the Rhizoma Anemarrhenae, Radix Platycodonis, Rhizoma Dioscoreae Septemlobae, Rhizoma Phragmitis, the Radix Stemonae and Caulis Bambusae In Taenia are cleaned, thinly slice, put into non iron container, the clear water adding boiled crude drug quality 6 times soaks 15 minutes, and moderate heat is heated to boiling, continues 10 minutes, add Herba Lepisori Thunbergiani, Fructus Seu Herba Pubescentis He Herba Polygoni Avicularis in clean Herba Dianthi, Usu again, turn little fire to decoct 20-30 minute (preferred: to turn little fire and decoct 25 minutes), Guan Huohou, filtration, collect filtrate;
(5) succinum is cleaned, smash also water and fly into smalls, mix homogeneously with step (2) (3) (4) made filtrate and medicated powder, obtain decoction.
Described a kind of preparation method for the treatment of the medicament decoction of urinary system calculus, step (2) turns little fire and decocts 35-45 minute (preferred: to turn little fire and decoct 40 minutes).
Described a kind of medicament for the treatment of urinary system calculus, be made into pharmaceutically acceptable unguentum, preparation method is:
(1) get Cortex Sclerotii Poriae, clear water is cleaned, and be cut into small pieces, put into frying pan, slow fire stir-fries burned black to surface, Guan Huohou, adds rice vinegar and mixes thoroughly, and moistening 10-20 minute (preferred: moistening 12-18 minute; Be more preferably: moistening 15 minutes), take out, dry and pulverize together with Crinis Carbonisatus;
(2) Pumex and Concha Ostreae removing impurity is got, clean, be ground into broken end, put into marmite, add vinegar water soaking 20 minutes, big fire is heated to boiling, turn little fire to decoct 35-45 minute (preferred: to turn little fire and decoct 40 minutes), medicinal residues are added water and continue decoction 30 minutes by filtering and collecting filter liquid, mixing twice gained filtrate after filtering;
(3) get Semen Lepidii (Semen Descurainiae) and clean impurity picked up by Fructus Psoraleae, clean with Chinese liquor rubbing, after drying, put into parch container, add crude salt, slow fire heats, constantly stir-fry 15-25 minute (preferred: constantly stir-fry 18-22 minute; Be more preferably: constantly stir-fry 20 minutes), take out, sieve and remove crude salt, pulverized 160 mesh sieves together with step (1) made crude drug;
(4) Radix Rubiae, the Rhizoma Anemarrhenae, Radix Platycodonis, Rhizoma Dioscoreae Septemlobae, Rhizoma Phragmitis, the Radix Stemonae and Caulis Bambusae In Taenia are cleaned, thinly slice, put into non iron container, add clear water and soak 15 minutes, moderate heat is heated to boiling, continues 10 minutes, add Herba Lepisori Thunbergiani, Fructus Seu Herba Pubescentis He Herba Polygoni Avicularis in clean Herba Dianthi, Usu again, turn little fire to decoct 20-30 minute (preferred: to turn little fire and decoct 25 minutes), Guan Huohou, filtration, collect filtrate;
(5) cleaned by succinum, smash also water and fly into smalls, mix with step (2) (3) (4) gained medicated powder and filtrate, heating is concentrated into thick paste, adds refined honey, stirs, obtain unguentum.
Described a kind of preparation method for the treatment of the medicament unguentum of urinary system calculus, the amount that step (5) adds refined honey is the 0.3-0.4 of thick paste quality doubly (preferred: the amount adding refined honey is 0.35 times of thick paste quality).
Described a kind of medicament for the treatment of urinary system calculus, be made into pharmaceutically acceptable powder, preparation method is:
(1) get Cortex Sclerotii Poriae, clear water is cleaned, and be cut into small pieces, put into frying pan, slow fire stir-fries burned black to surface, Guan Huohou, adds rice vinegar and mixes thoroughly, and moistening 10-20 minute (preferred: moistening 12-18 minute; Be more preferably: moistening 15 minutes), take out, dry and pulverize together with Crinis Carbonisatus;
(2) Pumex, Concha Ostreae and succinum removing impurity is got, clean, be ground into broken end, put into marmite, add vinegar water soaking 20 minutes, big fire is heated to boiling, turn little fire to decoct 35-45 minute (preferred: to turn little fire and decoct 40 minutes), medicinal residues are added water and continue decoction 30 minutes by filtering and collecting filter liquid, mixing twice gained filtrate after filtering;
(3) get Semen Lepidii (Semen Descurainiae) and clean impurity picked up by Fructus Psoraleae, clean with Chinese liquor rubbing, after drying, put into parch container, add crude salt, slow fire heats, constantly stir-fry 15-25 minute (preferred: constantly stir-fry 18-22 minute; Be more preferably: constantly stir-fry 20 minutes), take out, sieve and remove crude salt;
(4) Radix Rubiae, the Rhizoma Anemarrhenae, Radix Platycodonis, Rhizoma Dioscoreae Septemlobae, Rhizoma Phragmitis, the Radix Stemonae and Caulis Bambusae In Taenia are cleaned, thinly slice, put into non iron container, add clear water and soak 15 minutes, moderate heat is heated to boiling, continues 10 minutes, add Herba Lepisori Thunbergiani, Fructus Seu Herba Pubescentis He Herba Polygoni Avicularis in clean Herba Dianthi, Usu again, turn little fire to decoct 20-30 minute (preferred: to turn little fire and decoct 25 minutes), Guan Huohou, filtration, collect filtrate;
(5) blend step (2) (4) gained filtrate, spraying dry, pulverizes and sieves, obtains powder together with step (1) (3) gained crude drug.
Described a kind of preparation method for the treatment of the medicament powder of urinary system calculus, it is (preferred: to pulverize 140-160 mesh sieve that step (5) pulverized 120-180 mesh sieve; Be more preferably: pulverized 150 mesh sieves).
Described a kind of medicament for the treatment of urinary system calculus, be made into pharmaceutically acceptable tablet, its preparation method is:
(1) get Cortex Sclerotii Poriae, clear water is cleaned, and be cut into small pieces, put into frying pan, slow fire stir-fries burned black to surface, Guan Huohou, adds rice vinegar and mixes thoroughly, and moistening 10-20 minute (preferred: moistening 12-18 minute; Be more preferably: moistening 15 minutes), take out, dry and pulverize together with Crinis Carbonisatus;
(2) Pumex, Concha Ostreae and succinum removing impurity is got, clean, be ground into broken end, put into marmite, add vinegar water soaking 20 minutes, big fire is heated to boiling, turn little fire to decoct 35-45 minute (preferred: to turn little fire and decoct 40 minutes), medicinal residues are added water and continue decoction 30 minutes by filtering and collecting filter liquid, mixing twice gained filtrate after filtering;
(3) get Semen Lepidii (Semen Descurainiae) and clean impurity picked up by Fructus Psoraleae, clean with Chinese liquor rubbing, after drying, put into parch container, add crude salt, slow fire heats, constantly stir-fry 15-25 minute (preferred: constantly stir-fry 18-22 minute; Be more preferably: constantly stir-fry 20 minutes), take out, sieve and remove crude salt;
(4) Radix Rubiae, the Rhizoma Anemarrhenae, Radix Platycodonis, Rhizoma Dioscoreae Septemlobae, Rhizoma Phragmitis, the Radix Stemonae and Caulis Bambusae In Taenia are cleaned, thinly slice, put into non iron container, add clear water and soak 15 minutes, moderate heat is heated to boiling, continues 10 minutes, add Herba Lepisori Thunbergiani, Fructus Seu Herba Pubescentis He Herba Polygoni Avicularis in clean Herba Dianthi, Usu again, turn little fire to decoct 20-30 minute (preferred: to turn little fire and decoct 25 minutes), Guan Huohou, filtration, collect filtrate;
(5) blend step (2) (4) gained filtrate, spraying dry, pulverizes and sieves, is crushed to ellipse or round sheet dosage form, obtains tablet according to the preparation method of tablet together with step (1) (3) gained crude drug.
Described a kind of preparation method for the treatment of the medicament tablet of urinary system calculus, the specification of step (5) tablet is 0.3-0.5g/ grain (preferred: the specification of tablet is 0.4g/ grain).
A kind of reagent combination science for the treatment of urinary system calculus provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, the present invention is directed to urinary system calculus and all have significant curative effect, safety of taking medicine is without other untoward reaction;
2, this formula is summed up through clinical practice for many years and is formed, and has effect of heat-clearing and toxic substances removing, inducing diuresis for treating stranguria syndrome;
3, products obtained therefrom of the present invention, therapeutic effect is good, and cure rate is high, effectively can reduce relapse rate.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1treat a medicament for urinary system calculus, be prepared from (every part of 10g) primarily of following bulk drugs: Herba Dianthi 8 parts, Cortex Sclerotii Poriae 7 parts, Radix Rubiae 7 parts, the Rhizoma Anemarrhenae 9 parts, Herba Lepisori Thunbergiani 6 parts in Usu, Crinis Carbonisatus 6 parts, Pumex 8 parts, Fructus Seu Herba Pubescentis 8 parts, Concha Ostreae 4 parts, succinum (taking after mixing it with water) 4 parts, Radix Platycodonis 10 Fen , Herba Polygoni Avicularis 10 parts of Rhizoma Dioscoreae Septemlobae 8 parts, Rhizoma Phragmitis 9 parts, Semen Lepidii (Semen Descurainiae) 9 parts, the Radix Stemonae 6 parts, Caulis Bambusae In Taenia 10 parts, Fructus Psoraleae 10 parts.Above-mentioned a kind of preparation method for the treatment of the medicament decoction of urinary system calculus is:
(1) get Cortex Sclerotii Poriae, clear water is cleaned, and be cut into small pieces, put into frying pan, slow fire stir-fries burned black to surface, Guan Huohou, adds rice vinegar and mixes thoroughly, moistening 15 minutes, takes out, dries and pulverize together with Crinis Carbonisatus;
(2) get Pumex and Concha Ostreae removing impurity, clean, be ground into broken end, put into marmite, add vinegar water soaking 20 minutes, big fire is heated to boiling, turns little fire and decocts 40 minutes, medicinal residues are added water and continue decoction 30 minutes by filtering and collecting filter liquid, mixing twice gained filtrate after filtering;
(3) get Semen Lepidii (Semen Descurainiae) and clean impurity picked up by Fructus Psoraleae, clean with Chinese liquor rubbing, after drying, put into parch container, add crude salt, slow fire heats, and constantly stir-fries 20 minutes, takes out, sieve removes crude salt, pulverized 160 mesh sieves together with step (1) made crude drug;
(4) Radix Rubiae, the Rhizoma Anemarrhenae, Radix Platycodonis, Rhizoma Dioscoreae Septemlobae, Rhizoma Phragmitis, the Radix Stemonae and Caulis Bambusae In Taenia are cleaned, thinly slice, put into non iron container, the clear water adding boiled crude drug quality 6 times soaks 15 minutes, and moderate heat is heated to boiling, continues 10 minutes, add Herba Lepisori Thunbergiani, Fructus Seu Herba Pubescentis He Herba Polygoni Avicularis in clean Herba Dianthi, Usu again, turn little fire to decoct 25 minutes, Guan Huohou, filtration, collect filtrate;
(5) succinum is cleaned, smash also water and fly into smalls, mix homogeneously with step (2) (3) (4) made filtrate and medicated powder, obtain decoction.
embodiment 2treat a medicament for urinary system calculus, be prepared from (every part of 10g) primarily of following bulk drugs: Herba Dianthi 12 parts, Cortex Sclerotii Poriae 15 parts, Radix Rubiae 16 parts, the Rhizoma Anemarrhenae 15 parts, Herba Lepisori Thunbergiani 9 parts in Usu, Crinis Carbonisatus 9 parts, Pumex 14 parts, Fructus Seu Herba Pubescentis 16 parts, Concha Ostreae 9 parts, succinum (taking after mixing it with water) 9 parts, Radix Platycodonis 20 Fen , Herba Polygoni Avicularis 20 parts of Rhizoma Dioscoreae Septemlobae 16 parts, Rhizoma Phragmitis 15 parts, Semen Lepidii (Semen Descurainiae) 14 parts, the Radix Stemonae 9 parts, Caulis Bambusae In Taenia 20 parts, Fructus Psoraleae 20 parts.Above-mentioned a kind of preparation method for the treatment of the medicament unguentum of urinary system calculus is:
(1) get Cortex Sclerotii Poriae, clear water is cleaned, and be cut into small pieces, put into frying pan, slow fire stir-fries burned black to surface, Guan Huohou, adds rice vinegar and mixes thoroughly, moistening 15 minutes, takes out, dries and pulverize together with Crinis Carbonisatus;
(2) get Pumex and Concha Ostreae removing impurity, clean, be ground into broken end, put into marmite, add vinegar water soaking 20 minutes, big fire is heated to boiling, turns little fire and decocts 40 minutes, medicinal residues are added water and continue decoction 30 minutes by filtering and collecting filter liquid, mixing twice gained filtrate after filtering;
(3) get Semen Lepidii (Semen Descurainiae) and clean impurity picked up by Fructus Psoraleae, clean with Chinese liquor rubbing, after drying, put into parch container, add crude salt, slow fire heats, and constantly stir-fries 20 minutes, takes out, sieve removes crude salt, pulverized 160 mesh sieves together with step (1) made crude drug;
(4) Radix Rubiae, the Rhizoma Anemarrhenae, Radix Platycodonis, Rhizoma Dioscoreae Septemlobae, Rhizoma Phragmitis, the Radix Stemonae and Caulis Bambusae In Taenia are cleaned, thinly slice, put into non iron container, add clear water and soak 15 minutes, moderate heat is heated to boiling, continues 10 minutes, add Herba Lepisori Thunbergiani, Fructus Seu Herba Pubescentis He Herba Polygoni Avicularis in clean Herba Dianthi, Usu again, turn little fire to decoct 25 minutes, Guan Huohou, filtration, collect filtrate;
(5) cleaned by succinum, smash also water and fly into smalls, mix with step (2) (3) (4) gained medicated powder and filtrate, heating is concentrated into thick paste, adds the refined honey of thick paste quality 0.35 times, stirs, obtain unguentum.
Model case: xxx, male, 56 years old.Medical history: patient has intermittent stomachache, dysuria, and have hematuria, pyuria symptom, because of exacerbation of symptoms, pain is hard to bear, carrys out examination in hospital, through B ultrasonic display, two kidney Calculus, and a large amount of hydrops, dilatation of ureter, is diagnosed as two urological stone.
Take this example gained unguentum, each 6-10g, warm boiled water, one day twice 12 days is a course for the treatment of, after patient takes a course for the treatment of, hematuria, pyuria obviously alleviate, before urinating comparatively easily, and discharge calculus, after adhering to taking three courses for the treatment of, urinate smooth and easy, without other uncomfortable diseases, body is interior without calculus on inspection, recovery from illness.
embodiment 3treat a medicament for urinary system calculus, be prepared from (every part of 10g) primarily of following bulk drugs: Herba Dianthi 9 parts, Cortex Sclerotii Poriae 9 parts, Radix Rubiae 9 parts, the Rhizoma Anemarrhenae 11 parts, Herba Lepisori Thunbergiani 7 parts in Usu, Crinis Carbonisatus 7 parts, Pumex 10 parts, Fructus Seu Herba Pubescentis 10 parts, Concha Ostreae 5 parts, succinum (taking after mixing it with water) 5 parts, Radix Platycodonis 12 Fen , Herba Polygoni Avicularis 12 parts of Rhizoma Dioscoreae Septemlobae 10 parts, Rhizoma Phragmitis 11 parts, Semen Lepidii (Semen Descurainiae) 10 parts, the Radix Stemonae 7 parts, Caulis Bambusae In Taenia 12 parts, Fructus Psoraleae 12 parts.Above-mentioned a kind of preparation method for the treatment of the medicament powder of urinary system calculus is:
(1) get Cortex Sclerotii Poriae, clear water is cleaned, and be cut into small pieces, put into frying pan, slow fire stir-fries burned black to surface, Guan Huohou, adds rice vinegar and mixes thoroughly, moistening 15 minutes, takes out, dries and pulverize together with Crinis Carbonisatus;
(2) get Pumex, Concha Ostreae and succinum removing impurity, clean, be ground into broken end, put into marmite, add vinegar water soaking 20 minutes, big fire is heated to boiling, turns little fire and decocts 40 minutes, medicinal residues are added water and continue decoction 30 minutes by filtering and collecting filter liquid, mixing twice gained filtrate after filtering;
(3) get Semen Lepidii (Semen Descurainiae) and clean impurity picked up by Fructus Psoraleae, clean with Chinese liquor rubbing, after drying, put into parch container, add crude salt, slow fire heats, and constantly stir-fries 20 minutes, takes out, sieve removes crude salt;
(4) Radix Rubiae, the Rhizoma Anemarrhenae, Radix Platycodonis, Rhizoma Dioscoreae Septemlobae, Rhizoma Phragmitis, the Radix Stemonae and Caulis Bambusae In Taenia are cleaned, thinly slice, put into non iron container, add clear water and soak 15 minutes, moderate heat is heated to boiling, continues 10 minutes, add Herba Lepisori Thunbergiani, Fructus Seu Herba Pubescentis He Herba Polygoni Avicularis in clean Herba Dianthi, Usu again, turn little fire to decoct 25 minutes, Guan Huohou, filtration, collect filtrate;
(5) blend step (2) (4) gained filtrate, spraying dry, pulverized 150 mesh sieves, obtained powder together with step (1) (3) gained crude drug.
Model case: xxx, women, 27 years old.Main suit: stuttering urination difficulty, frequent micturition, urgent micturition, urine line comparatively thin and time have interruption, and have pain, during sexual intercourse, pain obviously increases the weight of, and goes to see a doctor, and through x-ray inspection, there is calculus at urethra place, is diagnosed as calculus of urethra.
Recommend to take this example gained powder, each 4-6g, warm boiled water, one day twice through people, within 12 days, be a course for the treatment of, after patient takes two weeks, discharge calculus, frequent micturition, urgent micturition phenomenon alleviate, after consolidating again a course for the treatment of, uncomfortable disease is all eliminated, and calculus of urethra disappears, and sexual life recovers harmonious.
embodiment 4treat a medicament for urinary system calculus, be prepared from (every part of 10g) primarily of following bulk drugs: Herba Dianthi 11 parts, Cortex Sclerotii Poriae 13 parts, Radix Rubiae 14 parts, the Rhizoma Anemarrhenae 13 parts, Herba Lepisori Thunbergiani 8 parts in Usu, Crinis Carbonisatus 8 parts, Pumex 12 parts, Fructus Seu Herba Pubescentis 14 parts, Concha Ostreae 8 parts, succinum (taking after mixing it with water) 8 parts, Radix Platycodonis 18 Fen , Herba Polygoni Avicularis 18 parts of Rhizoma Dioscoreae Septemlobae 14 parts, Rhizoma Phragmitis 13 parts, Semen Lepidii (Semen Descurainiae) 13 parts, the Radix Stemonae 8 parts, Caulis Bambusae In Taenia 18 parts, Fructus Psoraleae 18 parts.Above-mentioned a kind of preparation method for the treatment of the medicament tablet of urinary system calculus is:
(1) get Cortex Sclerotii Poriae, clear water is cleaned, and be cut into small pieces, put into frying pan, slow fire stir-fries burned black to surface, Guan Huohou, adds rice vinegar and mixes thoroughly, moistening 15 minutes, takes out, dries and pulverize together with Crinis Carbonisatus;
(2) get Pumex, Concha Ostreae and succinum removing impurity, clean, be ground into broken end, put into marmite, add vinegar water soaking 20 minutes, big fire is heated to boiling, turns little fire and decocts 40 minutes, medicinal residues are added water and continue decoction 30 minutes by filtering and collecting filter liquid, mixing twice gained filtrate after filtering;
(3) get Semen Lepidii (Semen Descurainiae) and clean impurity picked up by Fructus Psoraleae, clean with Chinese liquor rubbing, after drying, put into parch container, add crude salt, slow fire heats, and constantly stir-fries 20 minutes, takes out, sieve removes crude salt;
(4) Radix Rubiae, the Rhizoma Anemarrhenae, Radix Platycodonis, Rhizoma Dioscoreae Septemlobae, Rhizoma Phragmitis, the Radix Stemonae and Caulis Bambusae In Taenia are cleaned, thinly slice, put into non iron container, add clear water and soak 15 minutes, moderate heat is heated to boiling, continues 10 minutes, add Herba Lepisori Thunbergiani, Fructus Seu Herba Pubescentis He Herba Polygoni Avicularis in clean Herba Dianthi, Usu again, turn little fire to decoct 25 minutes, Guan Huohou, filtration, collect filtrate;
(5) blend step (2) (4) gained filtrate, spraying dry, pulverizes and sieves, is crushed to ellipse or round sheet dosage form according to the preparation method of tablet together with step (1) (3) gained crude drug, obtains tablet (specification is 0.4g/ grain).
Model case: xxx, male, 43 years old.Medical history: patient must have vesical calculus 3 years, often interrupts, dysuria when urinating, and with pain, during hyperkinesia, the state of an illness obviously increases the weight of, and occurs macroscopic hematuria, period once drug administration treatment, fail to adhere to taking, effect is bad.
Listen people to introduce Be very effective of the present invention, take this example gained tablet, each 3-4 grain, warm boiled water, one day twice, within 12 days, be a course for the treatment of, patient takes two courses for the treatment of, calculi in vivo obviously reduces, dysurea, dysuria remission, continue to take two courses for the treatment of, and self-induction is fully recovered, on inspection, intravesical calculus is all discharged.
embodiment 5treat a medicament for urinary system calculus, be prepared from (every part of 10g) primarily of following bulk drugs: Herba Dianthi 10 parts, Cortex Sclerotii Poriae 11 parts, Radix Rubiae 11.5 parts, the Rhizoma Anemarrhenae 12 parts, Herba Lepisori Thunbergiani 7.5 parts in Usu, Crinis Carbonisatus 7.5 parts, Pumex 11 parts, Fructus Seu Herba Pubescentis 12 parts, Concha Ostreae 6.5 parts, succinum (taking after mixing it with water) 6.5 parts, Radix Platycodonis 15 Fen , Herba Polygoni Avicularis 15 parts of Rhizoma Dioscoreae Septemlobae 12 parts, Rhizoma Phragmitis 12 parts, Semen Lepidii (Semen Descurainiae) 11.5 parts, the Radix Stemonae 7.5 parts, Caulis Bambusae In Taenia 15 parts, Fructus Psoraleae 15 parts.Above-mentioned a kind of preparation method for the treatment of the medicament of urinary system calculus is:
(1) get Cortex Sclerotii Poriae, clear water is cleaned, and be cut into small pieces, put into frying pan, slow fire stir-fries burned black to surface, Guan Huohou, adds rice vinegar and mixes thoroughly, moistening 15 minutes, takes out, dries and pulverize together with Crinis Carbonisatus;
(2) get Pumex and Concha Ostreae removing impurity, clean, be ground into broken end, put into marmite, add vinegar water soaking 20 minutes, big fire is heated to boiling, turns little fire and decocts 40 minutes, medicinal residues are added water and continue decoction 30 minutes by filtering and collecting filter liquid, mixing twice gained filtrate after filtering;
(3) get Semen Lepidii (Semen Descurainiae) and clean impurity picked up by Fructus Psoraleae, clean with Chinese liquor rubbing, after drying, put into parch container, add crude salt, slow fire heats, and constantly stir-fries 20 minutes, takes out, sieve removes crude salt, pulverized 160 mesh sieves together with step (1) made crude drug;
(4) Radix Rubiae, the Rhizoma Anemarrhenae, Radix Platycodonis, Rhizoma Dioscoreae Septemlobae, Rhizoma Phragmitis, the Radix Stemonae and Caulis Bambusae In Taenia are cleaned, thinly slice, put into non iron container, the clear water adding boiled crude drug quality 6 times soaks 15 minutes, and moderate heat is heated to boiling, continues 10 minutes, add Herba Lepisori Thunbergiani, Fructus Seu Herba Pubescentis He Herba Polygoni Avicularis in clean Herba Dianthi, Usu again, turn little fire to decoct 25 minutes, Guan Huohou, filtration, collect filtrate;
(5) succinum is cleaned, smash also water and fly into smalls, mix homogeneously with step (2) (3) (4) made filtrate and medicated powder, obtain decoction.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Herba Dianthi: base is former: be the wounded in the battle herb of pinkwort Herba Dianthi or Dianthus chinensis.Nature and flavor: bitter, cold.Gui Jing: enter the heart, kidney, small intestinal, urinary bladder channel.Function cures mainly: clearing away heat and promoting diuresis, and removing blood stasis stimulates the menstrual flow.Control urinary obstruction, gonorrhea, edema, amenorrhea, carbuncle, conjunctival congestion is hidden from view, contamination sore.
Cortex Sclerotii Poriae: base is former: be the crust of Polyporaceae plant poria cocos sclerotium.Nature and flavor: sweet light are flat.Function cures mainly: diuretic, detumescence.To harness the river swollen general edema.
Radix Rubiae: base is former: be the root and rhizome of Maguireothamnus speciosus Radix Rubiae.Chemical analysis: the root of Radix Rubiae is containing purple alizarin, alizarin, psedopurpurin, madder color.Nature and flavor: bitter, cold.Gui Jing: enter the heart.Liver Channel.Function cures mainly: promoting the circulation of blood is stopped blooding, dredge the meridian passage, eliminating phlegm and stopping cough.Control haematemesis, epistaxis, hematuria, have blood in stool, metrorrhagia, amenorrhea, rheumatic arthralgia, traumatic injury, the stasis of blood is stagnant to swell and ache, jaundice, chronic tracheitis.
The Rhizoma Anemarrhenae: nature and flavor: bitter, sweet, cold.Return lung, stomach, kidney channel.There is clearing away heat-fire, nourshing Yin and drynsessmoistening prescription effect.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.
Herba Lepisori Thunbergiani in Usu: base is former: be the herb of Herba Lepisori Thunbergiani in Plants of Polypodiaceae Usu.Nature and flavor: bitter; Flat; Nontoxic.Function cures mainly: heat-clearing and toxic substances removing; Diuresis; Cough-relieving; Hemostasis.Main dysuria; Urine leaching pain; Edema; Hematuria; Hygropyretic dysentery; Cough due to lung-heat; Asthma; Laryngopharynx swelling and pain; Sore swollen toxin; Rheumatalgia; Menoxenia; Traumatic injury; Knife injury is hemorrhage.
Crinis Carbonisatus: base is former: the carbide made for Crinis Carbonisatus.Get hair, removing impurity, aqueous alkali washes away grease, and clear water rinses, and dries, and boils in a covered pot over a slow fire and forges into charcoal, cool.Nature and flavor with return through: bitter, flat.Return liver, stomach warp.Function with cure mainly: astringing to arrest bleeding, blood stasis dispelling, diuresis.For spitting blood, spitting of blood, epistaxis, stranguria with blood, hematuria, has blood in stool, metrorrhagia, traumatic hemorrhage, dysuria.
Pumex: base is former: be the block of igneous rock rock Pumex or the skeleton of hilum section animal costazia aculeata Canu et Bassler, costazia costazii Audouin etc.Nature and flavor: salty, cold.Gui Jing: enter lung, kidney channel.Function cures mainly: lung heat clearing fire, changes old expectorant, softening the hard mass, treating stranguria.Control expectorant dyspnea of heat type to cough, old accumulation of phlegm block, goiter, scrofula, gonorrhea, hernia, skin ulcer swells, corneal nebula.
Fructus Seu Herba Pubescentis: base is former: be the Herb of eggplant kind of plant Fructus Seu Herba Pubescentis.Nature and flavor: bitter in the mouth; Cool in nature.Function cures mainly: heat-clearing and toxic substances removing.Main flu; Laryngalgia; Cough; Mumps; It suburb skin ulcer.
Concha Ostreae (preferred Concha Ostreae): base is former: be the shell of Ostreidae animal Crassostrea rivularis, long Concha Ostreae or Dalian Bay Concha Ostreae etc.Nature and flavor with return through: salty, be slightly cold.Return liver, gallbladder, kidney channel.There is tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, effect of hard masses softening and resolving.For insomnia of palpitating with fear, dizzy ear toot, scrofula sucutaneous nodule, abdominal mass abdominal mass mass in the abdomen.
Succinum: base is former: the resin of pinaceae plant buries in underground for ancient times, condense fossil sample material year in year out for a long time that be transformed.Composition: mainly resinous, volatile oil.Still containing succooxyabietic acid, succinoabietinolic acid, succinosilvic acid, succinoresinol, succinoabietol and succinic acid etc.Nature and flavor with return through: flat; Sweet; GUIXIN, liver, urinary bladder channel.There is tranquillizing the mind by relieving convulsion, promoting blood circulation to remove blood stasis, effect of inducing diuresis for treating stranguria syndrome.For malaise, palpitation and insomnia, infantile convulsion epilepsy, blood-stasis syndrome, stranguria, the difficulty in urination.
Radix Platycodonis: nature and flavor: bitter, pungent is flat.Gui Jing: return lung meridian.Effect: lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus.Cure mainly: for cough with copious phlegm, uncomfortable in chest smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.
Herba Polygoni Avicularis: base is former: be the herb of Liao section Zhi Wu Herba Polygoni Avicularis.Between Grain in Ear to Slight Heat, gather during stem and leaf riotous growth.Extract aerial parts, dry.Chemical analysis: herb Han Herba Polygoni Avicularis glycoside, quercitrin, d-cachou extract, gallic acid, caffeic acid, oxalic acid, silicic acid, chlorogenic acid, p-coumaric acid, cement, glucose, fructose and sucrose.Nature and flavor: bitter, cold.Gui Jing: enter urinary bladder channel.Function cures mainly: diuresis, heat clearing away, parasite killing.Control pyretic stranguria, the difficulty in urination, jaundice, the erosion of the vulva, leucorrhea, ascarid, infantile malnutrition, hemorrhoid swell, eczema.
Rhizoma Dioscoreae Septemlobae: base is former: be the rhizome of Dioscoreaceae Plant Powder back of the body Rhizoma Dioscoreae.Nature and flavor: bitter; Flat.Gui Jing: liver; Stomach; Urinary bladder channel.Function cures mainly: wind-damp dispelling; Dampness removing is turbid.Main stranguria marked by chyluria; Nebulousurine; Leukorrhagia; Skin infection; Eczema; Rheumatic arthralgia.
Rhizoma Phragmitis: base is former: be the rhizome of grass phragmites communis.Spring, summer, the autumn takes, and cleans earth, cuts off the upper fibrous root of residual stem, bud and joint, peels off membranaceous leaf, dry.Or be embedded in wet sand for using fresh herb.Nature and flavor: sweet, cold.Gui Jing: enter lung, stomach warp.Function cures mainly: heat clearing away, promotes the production of body fluid, relieving restlessness, preventing or arresting vomiting.Control calentura excessive thirst, gastropyretic vomiting, dysphagic, regurgitation, consumptive lung disease, lung abscess.And separate Fugu ocellatus ichthyotoxin.
Semen Lepidii (Semen Descurainiae): base is former: be the seed of crucifer Lepidium sativum L., North America semolina or descurainia sophia (l.) webb ex prantl.Chemical analysis: the fatty oil of Lepidium sativum L. seed, sinigrin, protein, saccharide.Nature and flavor: arduous, cold.Gui Jing: enter lung, urinary bladder channel.Function cures mainly: therapeutic method to keep the adverse QI flowing downwards row water.Control lung and stop up dyspnea with rapid respiration, expectorant bank is coughed, edema distension.
The Radix Stemonae: base is former: be the tuber of Stemonaceae plant Radix stemonae japonicae, Radix Stemonae or radix stemonae tuberosae etc.Nature and flavor: sweetness and bitterness, tepor.Gui Jing: enter lung meridian.Function cures mainly: gentle lung qi, cough-relieving, parasite killing.Control cough due to wind and cold, pertussis, pulmonary tuberculosis, old cough with asthma, ascarid, enterobiasis, skin scabies, eczema.
Caulis Bambusae In Taenia: base is former: the intermediate layer that the stem stalk for grass family Phyllostachys plant phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle, the blue or green pole bamboo of Thorny Sinobambusa plant, Sinocalamus plant major part allusion quotation bamboo etc. goes crust to scrape.Composition: the Caulis Bambusae In Taenia of phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle is containing phenolic constituent: 2,5-dimethoxy-1,4-benzoquinone, hydroxy benzaldehyde, syringic aldehyde, coniferyl aldehyde.Another containing p-phthalic acid 2 '-hydroxyethyl methyl ester.The property of medicine: sweet, is slightly cold.Return spleen, stomach, gallbladder meridian.Function cures mainly: removing heat-phlegm, relieves restlessness and prevents vomiting, safe and sound removing heat from blood.Cure mainly cough due to lung-heat, dysphoria with smothery sensation is palpitated with fear, and gastric heat is vomitted oh, pregnancy reactions, frequent fetal movement, spits blood, epistaxis, hematuria, metrorrhagia.
Fructus Psoraleae: base is former: be the dry mature fruit of legumes psoraleae.To gather during fruit maturation in autumn infructescence.Dry, rub fruit, removing impurity.Nature and flavor with return through: pungent, bitter, temperature.Return kidney, spleen channel.Function with cure mainly: warming the kidney to activate YANG, helping inspiration to relieve asthma, warming spleen and stopping diarrha; External pathogenic wind expelling speckle dispelling.For insufficiency of kidney-YANG, impotence and seminal emission, enuresis frequent micturition, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, Diarrhoea; External curing vitiligo, alopecia areata.
test example 1a kind of clinical practice for the treatment of the medicament (embodiment 5) of urinary system calculus of gained of the present invention:
Choose crowd: in December, 2013 in November ,-2014, according to medical case history, patient 394 example of urinary system calculus is had, male 214 example, women 180 example five hospital's screenings, age 25-60 year, 40.4 ± 1.2 years old mean age, wherein renal calculus 132 example, ureteral calculus 117 example, vesical calculus 86 example, other position calculus 59 examples.Diagnostic criteria: the visible calculus shade of 1 abdominal X-ray plain, B ultrasonic, radiography and CT; 2 unexpected abdominal part or the violent angor of waist; Visible hematuria under 3 naked eyes or mirror, hematuria aggravation during angor outbreak; 4 waist and bellies also radiate to hypogastric region, femoribus internus, perineal position; 5 costispinal angle percussion pains or side abdominal tenderness.All possess an arbitrary person in above-mentioned 1 double 2.3.4.5, namely diagnosable.
Before test, patient is divided into two groups at random, experimental group 270 example and matched group 124 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes a kind of medicament decoction for the treatment of urinary system calculus of gained of the present invention, one day twice, each 200-300ml, warmly takes, and within 12 days, is a course for the treatment of; Matched group takes other conventional medicines (PAISHI KELI, granules for treating nephrolith, Niaoshitong pills or Herba Lysimachiae etc.).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: clinical symptoms and sign disappear completely, and color ultrasound check calculus is got rid of external; (2) effective: clinical symptoms and sign disappear substantially, color ultrasound check calculus is discharged or reduces, but still has part to exist; (3) invalid: clinical symptoms and sign are not improved, and calculus does not excrete.
Clinical effectiveness: after the taking medicine of three courses for the treatment of, the therapeutic outcome of two groups is as shown in table 1:
As shown in Table 1, the healing patient of experimental group is 186 examples, and cure rate is 68.9%, effective patient is 78 examples, and effective percentage is 28.9%, and total effective rate is 97.8%, and the patient that matched group is cured is 65 examples, cure rate is 52.4%, and effective patient is 34 examples, and effective percentage is 27.4%, total effective rate 79.8%, significantly lower than the therapeutic effect of experimental group, illustrate that products obtained therefrom of the present invention is evident in efficacy, cure rate is high.
The Chinese medicine used in the present invention, utilize the clearing away heat and promoting diuresis of Herba Dianthi, the inducing diuresis to remove edema of Cortex Sclerotii Poriae, the dredge the meridian passage of Radix Rubiae, the clearing away heat-fire of the Rhizoma Anemarrhenae, the diuresis hemostasis of Herba Lepisori Thunbergiani in Usu, the blood stasis dispelling diuresis of Crinis Carbonisatus, the lung heat clearing pathogenic fire purging of Pumex, the heat-clearing and toxic substances removing of Fructus Seu Herba Pubescentis, the hard masses softening and resolving of Concha Ostreae, the inducing diuresis for treating stranguria syndrome of succinum, the evacuation of pus of eliminating the phlegm of Radix Platycodonis, the clearing away heat and promoting diuresis of Herba Polygoni Avicularis, the expelling wind and removing dampness of Rhizoma Dioscoreae Septemlobae, the clearing away heat and promoting production of body fluid of Rhizoma Phragmitis, the therapeutic method to keep the adverse QI flowing downwards row water of Semen Lepidii (Semen Descurainiae), the gentle lung qi of the Radix Stemonae, the removing heat-phlegm of Caulis Bambusae In Taenia, the multiple medical material synergism of warming the kidney to activate YANG of Fructus Psoraleae, play clearing away heat-damp and promoting diuresis altogether, effect of inducing diuresis for treating stranguria syndrome, effective discharge calculus, eliminate uncomfortable disease.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. treat a medicament for urinary system calculus, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Herba Dianthi 8-12; Cortex Sclerotii Poriae 7-15; Radix Rubiae 7-16; Rhizoma Anemarrhenae 9-15; Herba Lepisori Thunbergiani 6-9 in Usu; Crinis Carbonisatus 6-9; Pumex 8-14; Fructus Seu Herba Pubescentis 8-16; Concha Ostreae 4-9; Succinum (taking after mixing it with water) 4-9; Radix Platycodonis 10-20; Herba Polygoni Avicularis 10-20; Rhizoma Dioscoreae Septemlobae 8-16; Rhizoma Phragmitis 9-15; Semen Lepidii (Semen Descurainiae) 9-14; Radix Stemonae 6-9; Caulis Bambusae In Taenia 10-20; Fructus Psoraleae 10-20.
2. a kind of medicament for the treatment of urinary system calculus as claimed in claim 1, is characterized in that, Herba Dianthi 9-11; Cortex Sclerotii Poriae 9-13; Radix Rubiae 9-14; Rhizoma Anemarrhenae 11-13; Herba Lepisori Thunbergiani 7-8 in Usu; Crinis Carbonisatus 7-8; Pumex 10-12; Fructus Seu Herba Pubescentis 10-14; Concha Ostreae 5-8; Succinum (taking after mixing it with water) 5-8; Radix Platycodonis 12-18; Herba Polygoni Avicularis 12-18; Rhizoma Dioscoreae Septemlobae 10-14; Rhizoma Phragmitis 11-13; Semen Lepidii (Semen Descurainiae) 10-13; Radix Stemonae 7-8; Caulis Bambusae In Taenia 12-18; Fructus Psoraleae 12-18(is preferably: Herba Dianthi 10; Cortex Sclerotii Poriae 11; Radix Rubiae 11.5; The Rhizoma Anemarrhenae 12; Herba Lepisori Thunbergiani 7.5 in Usu; Crinis Carbonisatus 7.5; Pumex 11; Fructus Seu Herba Pubescentis 12; Concha Ostreae 6.5; Succinum (taking after mixing it with water) 6.5; Radix Platycodonis 15; Herba Polygoni Avicularis 15; Rhizoma Dioscoreae Septemlobae 12; Rhizoma Phragmitis 12; Semen Lepidii (Semen Descurainiae) 11.5; The Radix Stemonae 7.5; Caulis Bambusae In Taenia 15; Fructus Psoraleae 15).
3. a kind of medicament for the treatment of urinary system calculus as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Cortex Sclerotii Poriae, clear water is cleaned, and be cut into small pieces, put into frying pan, slow fire stir-fries burned black to surface, Guan Huohou, adds rice vinegar and mixes thoroughly, and moistening 10-20 minute (preferred: moistening 12-18 minute; Be more preferably: moistening 15 minutes), take out, dry and pulverize together with Crinis Carbonisatus;
(2) get Pumex and Concha Ostreae removing impurity, clean, be ground into broken end, put into marmite, add vinegar water soaking 20 minutes, big fire is heated to boiling, turns little fire and decocts, medicinal residues are added water and continue decoction 30 minutes by filtering and collecting filter liquid, mixing twice gained filtrate after filtering;
(3) get Semen Lepidii (Semen Descurainiae) and clean impurity picked up by Fructus Psoraleae, clean with Chinese liquor rubbing, after drying, put into parch container, add crude salt, slow fire heats, constantly stir-fry 15-25 minute (preferred: constantly stir-fry 18-22 minute; Be more preferably: constantly stir-fry 20 minutes), take out, sieve and remove crude salt, pulverized 160 mesh sieves together with step (1) made crude drug;
(4) Radix Rubiae, the Rhizoma Anemarrhenae, Radix Platycodonis, Rhizoma Dioscoreae Septemlobae, Rhizoma Phragmitis, the Radix Stemonae and Caulis Bambusae In Taenia are cleaned, thinly slice, put into non iron container, the clear water adding boiled crude drug quality 6 times soaks 15 minutes, and moderate heat is heated to boiling, continues 10 minutes, add Herba Lepisori Thunbergiani, Fructus Seu Herba Pubescentis He Herba Polygoni Avicularis in clean Herba Dianthi, Usu again, turn little fire to decoct 20-30 minute (preferred: to turn little fire and decoct 25 minutes), Guan Huohou, filtration, collect filtrate;
(5) succinum is cleaned, smash also water and fly into smalls, mix homogeneously with step (2) (3) (4) made filtrate and medicated powder, obtain decoction.
4. a kind of preparation method for the treatment of the medicament decoction of urinary system calculus as claimed in claim 3, is characterized in that, step (2) turns little fire and decocts 35-45 minute (preferred: to turn little fire and decoct 40 minutes).
5. a kind of medicament for the treatment of urinary system calculus as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable unguentum, its preparation method is:
(1) get Cortex Sclerotii Poriae, clear water is cleaned, and be cut into small pieces, put into frying pan, slow fire stir-fries burned black to surface, Guan Huohou, adds rice vinegar and mixes thoroughly, and moistening 10-20 minute (preferred: moistening 12-18 minute; Be more preferably: moistening 15 minutes), take out, dry and pulverize together with Crinis Carbonisatus;
(2) Pumex and Concha Ostreae removing impurity is got, clean, be ground into broken end, put into marmite, add vinegar water soaking 20 minutes, big fire is heated to boiling, turn little fire to decoct 35-45 minute (preferred: to turn little fire and decoct 40 minutes), medicinal residues are added water and continue decoction 30 minutes by filtering and collecting filter liquid, mixing twice gained filtrate after filtering;
(3) get Semen Lepidii (Semen Descurainiae) and clean impurity picked up by Fructus Psoraleae, clean with Chinese liquor rubbing, after drying, put into parch container, add crude salt, slow fire heats, constantly stir-fry 15-25 minute (preferred: constantly stir-fry 18-22 minute; Be more preferably: constantly stir-fry 20 minutes), take out, sieve and remove crude salt, pulverized 160 mesh sieves together with step (1) made crude drug;
(4) Radix Rubiae, the Rhizoma Anemarrhenae, Radix Platycodonis, Rhizoma Dioscoreae Septemlobae, Rhizoma Phragmitis, the Radix Stemonae and Caulis Bambusae In Taenia are cleaned, thinly slice, put into non iron container, add clear water and soak 15 minutes, moderate heat is heated to boiling, continues 10 minutes, add Herba Lepisori Thunbergiani, Fructus Seu Herba Pubescentis He Herba Polygoni Avicularis in clean Herba Dianthi, Usu again, turn little fire to decoct 20-30 minute (preferred: to turn little fire and decoct 25 minutes), Guan Huohou, filtration, collect filtrate;
(5) cleaned by succinum, smash also water and fly into smalls, mix with step (2) (3) (4) gained medicated powder and filtrate, heating is concentrated into thick paste, adds refined honey, stirs, obtain unguentum.
6. a kind of preparation method for the treatment of the medicament unguentum of urinary system calculus as claimed in claim 5, is characterized in that, the amount that step (5) adds refined honey is the 0.3-0.4 of thick paste quality doubly (preferred: the amount adding refined honey is 0.35 times of thick paste quality).
7. a kind of medicament for the treatment of urinary system calculus as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Cortex Sclerotii Poriae, clear water is cleaned, and be cut into small pieces, put into frying pan, slow fire stir-fries burned black to surface, Guan Huohou, adds rice vinegar and mixes thoroughly, and moistening 10-20 minute (preferred: moistening 12-18 minute; Be more preferably: moistening 15 minutes), take out, dry and pulverize together with Crinis Carbonisatus;
(2) Pumex, Concha Ostreae and succinum removing impurity is got, clean, be ground into broken end, put into marmite, add vinegar water soaking 20 minutes, big fire is heated to boiling, turn little fire to decoct 35-45 minute (preferred: to turn little fire and decoct 40 minutes), medicinal residues are added water and continue decoction 30 minutes by filtering and collecting filter liquid, mixing twice gained filtrate after filtering;
(3) get Semen Lepidii (Semen Descurainiae) and clean impurity picked up by Fructus Psoraleae, clean with Chinese liquor rubbing, after drying, put into parch container, add crude salt, slow fire heats, constantly stir-fry 15-25 minute (preferred: constantly stir-fry 18-22 minute; Be more preferably: constantly stir-fry 20 minutes), take out, sieve and remove crude salt;
(4) Radix Rubiae, the Rhizoma Anemarrhenae, Radix Platycodonis, Rhizoma Dioscoreae Septemlobae, Rhizoma Phragmitis, the Radix Stemonae and Caulis Bambusae In Taenia are cleaned, thinly slice, put into non iron container, add clear water and soak 15 minutes, moderate heat is heated to boiling, continues 10 minutes, add Herba Lepisori Thunbergiani, Fructus Seu Herba Pubescentis He Herba Polygoni Avicularis in clean Herba Dianthi, Usu again, turn little fire to decoct 20-30 minute (preferred: to turn little fire and decoct 25 minutes), Guan Huohou, filtration, collect filtrate;
(5) blend step (2) (4) gained filtrate, spraying dry, pulverizes and sieves, obtains powder together with step (1) (3) gained crude drug.
8. a kind of preparation method for the treatment of the medicament powder of urinary system calculus as claimed in claim 7, is characterized in that, it is (preferred: to pulverize 140-160 mesh sieve that step (5) pulverized 120-180 mesh sieve; Be more preferably: pulverized 150 mesh sieves).
9. a kind of medicament for the treatment of urinary system calculus as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable tablet, its preparation method is:
(1) get Cortex Sclerotii Poriae, clear water is cleaned, and be cut into small pieces, put into frying pan, slow fire stir-fries burned black to surface, Guan Huohou, adds rice vinegar and mixes thoroughly, and moistening 10-20 minute (preferred: moistening 12-18 minute; Be more preferably: moistening 15 minutes), take out, dry and pulverize together with Crinis Carbonisatus;
(2) Pumex, Concha Ostreae and succinum removing impurity is got, clean, be ground into broken end, put into marmite, add vinegar water soaking 20 minutes, big fire is heated to boiling, turn little fire to decoct 35-45 minute (preferred: to turn little fire and decoct 40 minutes), medicinal residues are added water and continue decoction 30 minutes by filtering and collecting filter liquid, mixing twice gained filtrate after filtering;
(3) get Semen Lepidii (Semen Descurainiae) and clean impurity picked up by Fructus Psoraleae, clean with Chinese liquor rubbing, after drying, put into parch container, add crude salt, slow fire heats, constantly stir-fry 15-25 minute (preferred: constantly stir-fry 18-22 minute; Be more preferably: constantly stir-fry 20 minutes), take out, sieve and remove crude salt;
(4) Radix Rubiae, the Rhizoma Anemarrhenae, Radix Platycodonis, Rhizoma Dioscoreae Septemlobae, Rhizoma Phragmitis, the Radix Stemonae and Caulis Bambusae In Taenia are cleaned, thinly slice, put into non iron container, add clear water and soak 15 minutes, moderate heat is heated to boiling, continues 10 minutes, add Herba Lepisori Thunbergiani, Fructus Seu Herba Pubescentis He Herba Polygoni Avicularis in clean Herba Dianthi, Usu again, turn little fire to decoct 20-30 minute (preferred: to turn little fire and decoct 25 minutes), Guan Huohou, filtration, collect filtrate;
(5) blend step (2) (4) gained filtrate, spraying dry, pulverizes and sieves, is crushed to ellipse or round sheet dosage form, obtains tablet according to the preparation method of tablet together with step (1) (3) gained crude drug.
10. a kind of preparation method for the treatment of the medicament tablet of urinary system calculus as claimed in claim 9, is characterized in that, the specification of step (5) tablet is 0.3-0.5g/ grain (preferred: the specification of tablet is 0.4g/ grain).
CN201510163942.6A 2015-04-09 2015-04-09 Medicament for treating lithiasis in urinary system and preparation method thereof Pending CN104707055A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102078440A (en) * 2009-11-26 2011-06-01 赵莉 Traditional Chinese medicine composition for kidney calculi

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102078440A (en) * 2009-11-26 2011-06-01 赵莉 Traditional Chinese medicine composition for kidney calculi

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
赖海标等: "中医药防治肾结石的临床研究进展", 《中国药业》 *

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