CN104703667B - 流体系统中的压力控制 - Google Patents

流体系统中的压力控制 Download PDF

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Publication number
CN104703667B
CN104703667B CN201380052565.8A CN201380052565A CN104703667B CN 104703667 B CN104703667 B CN 104703667B CN 201380052565 A CN201380052565 A CN 201380052565A CN 104703667 B CN104703667 B CN 104703667B
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China
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fluid
pressure
permeable medium
channel
fluid channel
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CN201380052565.8A
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English (en)
Chinese (zh)
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CN104703667A (zh
Inventor
安德烈亚·阿达莫
亚历山大·P·克莱顿
帕特里克·路易斯·海德尔
诺蓬·维拉诺帕南
克拉夫斯·F·詹森
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Massachusetts Institute of Technology
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Massachusetts Institute of Technology
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Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K15/00—Check valves
    • F16K15/14—Check valves with flexible valve members
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
    • F16K99/0015—Diaphragm or membrane valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0034—Operating means specially adapted for microvalves
    • F16K99/0055—Operating means specially adapted for microvalves actuated by fluids
    • F16K99/0057—Operating means specially adapted for microvalves actuated by fluids the fluid being the circulating fluid itself, e.g. check valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0673—Handling of plugs of fluid surrounded by immiscible fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0874—Three dimensional network
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0655—Valves, specific forms thereof with moving parts pinch valves
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/7722—Line condition change responsive valves
    • Y10T137/7781—With separate connected fluid reactor surface
    • Y10T137/7793—With opening bias [e.g., pressure regulator]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/8593—Systems
    • Y10T137/87249—Multiple inlet with multiple outlet

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Control Of Fluid Pressure (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN201380052565.8A 2012-08-10 2013-08-09 流体系统中的压力控制 Active CN104703667B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261681881P 2012-08-10 2012-08-10
US61/681,881 2012-08-10
US201361841491P 2013-07-01 2013-07-01
US61/841,491 2013-07-01
PCT/US2013/054312 WO2014026098A2 (en) 2012-08-10 2013-08-09 Pressure control in fluidic systems

Publications (2)

Publication Number Publication Date
CN104703667A CN104703667A (zh) 2015-06-10
CN104703667B true CN104703667B (zh) 2017-03-08

Family

ID=50068727

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380052565.8A Active CN104703667B (zh) 2012-08-10 2013-08-09 流体系统中的压力控制

Country Status (5)

Country Link
US (1) US9927038B2 (enExample)
EP (1) EP2882509B1 (enExample)
CN (1) CN104703667B (enExample)
IN (1) IN2015DN01723A (enExample)
WO (1) WO2014026098A2 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017143197A1 (en) 2016-02-17 2017-08-24 Continuus Pharmaceuticals, Inc. Continuous separator bypass systems and methods of use thereof
DE102018101087A1 (de) * 2018-01-18 2019-07-18 Vaillant Gmbh Gasabscheider
EP3834210A1 (en) 2018-08-07 2021-06-16 Technical University of Denmark Separation of radiometals
US10987671B2 (en) 2019-04-05 2021-04-27 Zaiput Flow Technologies LLC Reservoir-based management of volumetric flow rate in fluidic systems
CN116887901A (zh) * 2021-01-11 2023-10-13 扎伊普特流动技术有限责任公司 流体分离器及相关方法
EP4539953A1 (en) 2022-06-15 2025-04-23 Zaiput Flow Technologies LLC Systems and methods for separation of chemical species, such as cannabinoids, using multiple liquid phases
CN115646563A (zh) * 2022-10-14 2023-01-31 广州迪澳医疗科技有限公司 一种微流控芯片及其制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5186431A (en) * 1989-09-22 1993-02-16 Yehuda Tamari Pressure sensitive valves for extracorporeal circuits
US6187196B1 (en) * 1996-05-17 2001-02-13 Colorado School Of Mines Membrane separation of components in a fluid mixture
CN101296743A (zh) * 2005-08-24 2008-10-29 加利福尼亚大学董事会 用于纳米级物质快速传输的膜

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US5076943A (en) 1984-09-10 1991-12-31 Rakow Allen L Fluid particle separator with pressure drop resistance matching
EP0766594B1 (en) 1994-06-22 2002-10-23 Fls Miljo A/S Mass transfer apparatus
US6454945B1 (en) 1995-06-16 2002-09-24 University Of Washington Microfabricated devices and methods
WO1997000442A1 (en) 1995-06-16 1997-01-03 The University Of Washington Microfabricated differential extraction device and method
US5942443A (en) 1996-06-28 1999-08-24 Caliper Technologies Corporation High throughput screening assay systems in microscale fluidic devices
US6274089B1 (en) 1998-06-08 2001-08-14 Caliper Technologies Corp. Microfluidic devices, systems and methods for performing integrated reactions and separations
GB9822185D0 (en) 1998-10-13 1998-12-02 Zeneca Ltd Device
JP2003532871A (ja) 2000-04-14 2003-11-05 カリパー・テクノロジーズ・コープ． ターゲットプーリングを使用するスクリーニングアッセイ及びシステム
US6666909B1 (en) 2000-06-06 2003-12-23 Battelle Memorial Institute Microsystem capillary separations
WO2002068821A2 (en) 2001-02-28 2002-09-06 Lightwave Microsystems Corporation Microfluidic control using dieletric pumping
US6662818B2 (en) 2002-02-01 2003-12-16 Perseptive Biosystems, Inc. Programmable tracking pressure regulator for control of higher pressures in microfluidic circuits
US8075778B2 (en) 2003-03-25 2011-12-13 Massachusetts Institute Of Technology Fluid separation
US7604965B2 (en) 2003-04-03 2009-10-20 Fluidigm Corporation Thermal reaction device and method for using the same
DE10340012A1 (de) 2003-08-30 2005-04-07 Roche Diagnostics Gmbh Vorrichtung zur Gas-oder Flüssigkeitsabscheidung aus mikrofluidischen Durchflusssystemen
JP3956964B2 (ja) * 2003-09-25 2007-08-08 ブラザー工業株式会社 液体移送装置及び圧電アクチュエータ
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Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5186431A (en) * 1989-09-22 1993-02-16 Yehuda Tamari Pressure sensitive valves for extracorporeal circuits
US6187196B1 (en) * 1996-05-17 2001-02-13 Colorado School Of Mines Membrane separation of components in a fluid mixture
CN101296743A (zh) * 2005-08-24 2008-10-29 加利福尼亚大学董事会 用于纳米级物质快速传输的膜

Also Published As

Publication number Publication date
US20150285387A1 (en) 2015-10-08
US9927038B2 (en) 2018-03-27
CN104703667A (zh) 2015-06-10
EP2882509B1 (en) 2020-05-27
WO2014026098A3 (en) 2014-03-27
WO2014026098A2 (en) 2014-02-13
WO2014026098A8 (en) 2015-04-23
EP2882509A4 (en) 2016-04-06
IN2015DN01723A (enExample) 2015-05-22
EP2882509A2 (en) 2015-06-17

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