CN104703583A - 经修饰的透明质酸衍生物及其用途 - Google Patents

经修饰的透明质酸衍生物及其用途 Download PDF

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Publication number
CN104703583A
CN104703583A CN201380052657.6A CN201380052657A CN104703583A CN 104703583 A CN104703583 A CN 104703583A CN 201380052657 A CN201380052657 A CN 201380052657A CN 104703583 A CN104703583 A CN 104703583A
Authority
CN
China
Prior art keywords
derivatives
formula
hyaluronic acids
hyaluronic acid
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201380052657.6A
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English (en)
Chinese (zh)
Inventor
A·迪皮特罗
F·卡瓦萨
P·卡利切蒂
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Publication of CN104703583A publication Critical patent/CN104703583A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Birds (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
CN201380052657.6A 2012-10-09 2013-10-07 经修饰的透明质酸衍生物及其用途 Pending CN104703583A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12187828 2012-10-09
EP12187828.4 2012-10-09
PCT/EP2013/070814 WO2014056841A1 (en) 2012-10-09 2013-10-07 Modified hyaluronic acid derivatives and use thereof

Publications (1)

Publication Number Publication Date
CN104703583A true CN104703583A (zh) 2015-06-10

Family

ID=47022522

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380052657.6A Pending CN104703583A (zh) 2012-10-09 2013-10-07 经修饰的透明质酸衍生物及其用途

Country Status (21)

Country Link
US (1) US20150252120A1 (cg-RX-API-DMAC10.html)
EP (1) EP2906193B1 (cg-RX-API-DMAC10.html)
JP (1) JP2015533190A (cg-RX-API-DMAC10.html)
KR (1) KR20150065861A (cg-RX-API-DMAC10.html)
CN (1) CN104703583A (cg-RX-API-DMAC10.html)
AR (1) AR092922A1 (cg-RX-API-DMAC10.html)
AU (1) AU2013328842A1 (cg-RX-API-DMAC10.html)
BR (1) BR112015007823A2 (cg-RX-API-DMAC10.html)
CA (1) CA2886144A1 (cg-RX-API-DMAC10.html)
CL (1) CL2015000803A1 (cg-RX-API-DMAC10.html)
EA (1) EA201590708A1 (cg-RX-API-DMAC10.html)
HK (1) HK1210941A1 (cg-RX-API-DMAC10.html)
IL (1) IL238103A0 (cg-RX-API-DMAC10.html)
IN (1) IN2015DN02358A (cg-RX-API-DMAC10.html)
MX (1) MX2015004386A (cg-RX-API-DMAC10.html)
PE (1) PE20150713A1 (cg-RX-API-DMAC10.html)
PH (1) PH12015500585A1 (cg-RX-API-DMAC10.html)
SG (1) SG11201501992XA (cg-RX-API-DMAC10.html)
TW (1) TW201414478A (cg-RX-API-DMAC10.html)
WO (1) WO2014056841A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA201503171B (cg-RX-API-DMAC10.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112154158A (zh) * 2018-03-22 2020-12-29 持田制药株式会社 连接有非甾体抗炎化合物的海藻酸衍生物

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI614005B (zh) * 2014-05-26 2018-02-11 National Taipei University Of Technology 水膠組合物的用途
DE102014016158A1 (de) * 2014-07-11 2016-01-14 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Zusammensetzung zur Behandlung von Magenbeschwerden
WO2017116273A1 (en) * 2015-12-30 2017-07-06 Asafov Alexander Vilenovich Formulation for treatment of peripheral joints, spinal joints and/or extracellular matrix elements of connective tissue, method of manufacture and uses
RU2625766C1 (ru) * 2016-07-19 2017-07-18 Александр Ливиевич Ураков Средство для экстренного восстановления голоса при внезапной афонии
US12233087B2 (en) 2018-05-16 2025-02-25 Emory University Palladium hyaluronic acid particles and methods of managing cancer or angiogenic conditions

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000029030A1 (en) * 1998-11-13 2000-05-25 Continental Projects Limited Complexes of hyaluronic acid/carnitines and pharmaceutical and cosmetic compositions
CN101277675A (zh) * 2005-09-30 2008-10-01 昭和电工株式会社 肉碱衍生物、其盐、皮肤外用制剂和化妆品材料
US20110027357A1 (en) * 2004-02-18 2011-02-03 Isaac Gilinski Compositions and methods for timed release of water-soluble nutritional supplements

Family Cites Families (16)

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US4716224A (en) 1984-05-04 1987-12-29 Seikagaku Kogyo Co. Ltd. Crosslinked hyaluronic acid and its use
US4851521A (en) 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
GB8713662D0 (en) 1987-06-11 1987-07-15 Skandigen Ab Hyaluronic acid derivatives
US4839159A (en) 1988-02-08 1989-06-13 Topicarn, Inc. Topical L-carnitine composition
IT1219587B (it) 1988-05-13 1990-05-18 Fidia Farmaceutici Polisaccaridi carbossiilici autoreticolati
IT1251151B (it) 1991-08-05 1995-05-04 Fidia Spa Materiale spugnoso essenzialmente costituito da acido ialuronico,o suoi derivati
US6129761A (en) 1995-06-07 2000-10-10 Reprogenesis, Inc. Injectable hydrogel compositions
WO2002090390A1 (en) 2001-05-04 2002-11-14 University Of Utah Research Foundation Hyaluronic acid containing bioconjugates : targeted delivery of anti-cancer drugs to cancer cells
ITMI20021666A1 (it) 2002-07-26 2004-01-26 Jasper Ltd Liability Co Derivati dell'acido ialuronico
US20060134147A1 (en) 2004-12-21 2006-06-22 Avon Products, Inc. Cosmetic compositions having carnitine creatinate and methods for using
CN101133102A (zh) 2004-12-30 2008-02-27 诺维信生物聚合物公司 与α-羟酸的聚合物连接的透明质酸
ITMI20052035A1 (it) 2005-10-26 2007-04-27 Professional Dietetics Srl Composizioni farmaceutiche cicatrizzanti sotto forma di crema a base di amminoacidi e sodio ialuronato
EP1884231A1 (en) 2006-08-01 2008-02-06 Auriga International S.A. Cosmetic or pharmaceutical composition containing hyaluronic acid
AU2007353211B2 (en) 2007-05-11 2013-08-29 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Gel useful for the delivery of cosmetic active ingredients
CA2687983A1 (en) 2007-05-23 2008-12-04 Allergan, Inc. Coated hyaluronic acid particles
WO2010003797A1 (en) 2008-07-09 2010-01-14 Novozymes Biopharma Dk A/S Hyaluronic acid for corneal wound healing

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000029030A1 (en) * 1998-11-13 2000-05-25 Continental Projects Limited Complexes of hyaluronic acid/carnitines and pharmaceutical and cosmetic compositions
US20110027357A1 (en) * 2004-02-18 2011-02-03 Isaac Gilinski Compositions and methods for timed release of water-soluble nutritional supplements
CN101277675A (zh) * 2005-09-30 2008-10-01 昭和电工株式会社 肉碱衍生物、其盐、皮肤外用制剂和化妆品材料

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112154158A (zh) * 2018-03-22 2020-12-29 持田制药株式会社 连接有非甾体抗炎化合物的海藻酸衍生物

Also Published As

Publication number Publication date
PE20150713A1 (es) 2015-05-16
AU2013328842A1 (en) 2015-04-09
WO2014056841A1 (en) 2014-04-17
EP2906193B1 (en) 2016-09-28
CL2015000803A1 (es) 2015-08-07
US20150252120A1 (en) 2015-09-10
IL238103A0 (en) 2015-05-31
PH12015500585A1 (en) 2015-05-04
JP2015533190A (ja) 2015-11-19
IN2015DN02358A (cg-RX-API-DMAC10.html) 2015-09-04
CA2886144A1 (en) 2014-04-17
ZA201503171B (en) 2016-11-30
BR112015007823A2 (pt) 2017-07-04
KR20150065861A (ko) 2015-06-15
EA201590708A1 (ru) 2015-07-30
EP2906193A1 (en) 2015-08-19
TW201414478A (zh) 2014-04-16
HK1210941A1 (en) 2016-05-13
SG11201501992XA (en) 2015-04-29
MX2015004386A (es) 2015-06-10
AR092922A1 (es) 2015-05-06

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