CN104689229A - Traditional Chinese medicine composition for treating hyperplasia of mammary glands - Google Patents

Traditional Chinese medicine composition for treating hyperplasia of mammary glands Download PDF

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CN104689229A
CN104689229A CN201510057492.2A CN201510057492A CN104689229A CN 104689229 A CN104689229 A CN 104689229A CN 201510057492 A CN201510057492 A CN 201510057492A CN 104689229 A CN104689229 A CN 104689229A
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刘清军
郑德先
尚毅
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Abstract

The invention discloses a traditional Chinese medicine composition for treating the hyperplasia of mammary glands and belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine is prepared from the following raw material medicines in parts by weight: 90 parts of radix bupleuri, 90 parts of rhizoma cyperi, 30 parts of rhizoma corydalis, 30 parts of curcuma zedoary, 20 parts of Tuckahoe, 20 parts of seaweed, 20 parts of pinellia ternate, 15 parts of semen vaccariae, 15 parts of tangerine seed, 20 parts of radix puerariae, 20 parts of parasitic loranthus, 20 parts of dogwood, 20 parts of gizzard pepsin, 10 parts of glossy privet fruit and 10 parts of scorched hawthorn fruit. The traditional Chinese medicine composition is rapid in effect taking, reliable in effect, high in recovery rate and free of obvious toxic side effect, and the hyperplasia of mammary glands can be relieved in a short time, and the medical complication can be controlled and the disease-resistant recovery capability can be improved.

Description

A kind of Chinese medicine composition for the treatment of cyclomastopathy
Technical field
The present invention relates to a kind of Chinese medicine, specifically relate to a kind of Chinese medicine composition for the treatment of cyclomastopathy.
Background technology
Cyclomastopathy has a strong impact on one of able-bodied common disease of numerous women at present.Have both at home and abroad every year a large amount of patients because suffering from cyclomastopathy sup sorrow, even affect work and life, if treat not in time, exacerbation of symptoms even secondary canceration can be caused.Therefore, thoroughly curing cyclomastopathy is one of pendulum most significant task in face of related medical scientific research institution and numerous medical personnels, is also the effort target of each medical personnel.Main and the endocrine disturbance of its cause of disease or spiritual feelings will have substantial connection, and the mammary gland of Women of Childbearing Age is subject to ovaryendocrine controlled, once ovarian function is subject to the impact of certain factor, and such as emotional instability, depressed, overworked, inharmonious sexual life, living environment transition, or surfeit contains hormonetonic and the life-time service cosmetics containing hormonal components etc., all can affect the out of proportion of the secretion of estrogen and progestogen in human body or Secretion Rhyme is disorderly and cause mammoplasia.
At present, the remedy measures that the vast cyclomastopathy patient of China mainly adopts and method are western medicine, naturopathy, therapy of combining Chinese and Western medicine and Chinese traditional treatment, adopt single Therapeutic Method or conbined usage according to the concrete condition of patient, but the therapeutic effect received also is far from reaching the expection of medical research mechanism, medical institutions, doctor, families of patients and patient.Although western medicine is comparatively rapid, easily repeatedly, and there is certain side effect.Select the method treatments such as cup, acupuncture, scrape therapy, massage, have certain misery, and curative effect is comparatively slow, be difficult to cure completely.Certainly we do not deny that the treatment of indivedual cyclomastopathy patient is desirable sometimes yet, but the too low present situation of overall cure rate is objective reality.Along with the progress and development of science and technology, the method that people treat this disease also gets more and more.As the use in conjunction etc. of one or more methods above-mentioned.Make us have very much progress for the treatment technology of cyclomastopathy, but these researchs also do not make substantial breakthroughs at present, because these treatment meanss treatment cyclomastopathy respectively has the deficiency of some aspect.
The present situation for the treatment of by Chinese herbs is not also adopted at present widely, often not by the remedy measures as first-selection, sometimes just as a kind of auxiliary Therapeutic Method, namely while the treatment of employing western medical treatment, naturopathy or combinational therapeutic methods, as a kind of auxiliary treatment.What have is then a kind of helpless Therapeutic Method adopted after western medical treatment is undesirable.Chinese medicine residing awkward present situation in treatment cyclomastopathy process is because Chinese medicine is to the uncertainty of this sick therapeutic effect, this present situation result also in the embarrassment of Chinese medicine residing status in treatment cyclomastopathy process and passive, this present situation also often causes due to therapic opportunity problem and is not sure, cause Chinese medicine not play its effect that should play in treatment cyclomastopathy process, the more important thing is due to Chinese medicine effect uncertainty with do not possess universality and use meaning to cause.
Chinese medicine should give full play to its due therapeutical effect in cyclomastopathy therapeutic process, a kind of measure and the method that can play separately effective therapeutical effect or very good therapeutical effect must be become, so just can accomplish disease that let slip no opportunity, that heal the sick effectively, thoroughly.Certainly, let us also not oppose at some time and western medicine and medical practitioners is treated, " massage ", " acupuncture and moxibustion therapy ", " cupping for treatment ", the remedy measures such as " scrape therapy " use simultaneously, but the Chinese medicine of cyclomastopathy should as a kind of adoptable positive Therapeutic Method and measure.Thus existing be commercially badly in need of having determine curative effect and there is the disease that can heal the sick that generally uses meaning or significantly symptom management development, reduce the Chinese medicine preparation of the treatment cyclomastopathy of the misery of patient.
summary of the invention:
In order to overcome the shortcoming that above-mentioned prior art exists, the object of the present invention is to provide one that cyclomastopathy can be made to be controlled, thus a kind of Chinese medicine composition that the disease of patient is more thoroughly cured.
Technical scheme of the present invention is:
Treating a Chinese medicine composition for cyclomastopathy, is be made up of the crude drug of following weight parts: Radix Bupleuri 90 parts, Rhizoma Cyperi 90 parts, Rhizoma Corydalis 30 parts, Rhizoma Curcumae 30 parts, 20 parts, Poria, Sargassum 20 parts, the Rhizoma Pinelliae 20 parts, Semen Vaccariae 15 parts, Semen Citri Reticulatae 15 parts, Radix Puerariae 20 parts, Herba Taxilli 20 parts, Fructus Corni 20 parts, Endothelium Corneum Gigeriae Galli 20 parts, Fructus Ligustri Lucidi 10 parts, Fructus Crataegi (parched to brown) 10 parts.
General adult patient is required use one the course for the treatment of dose be: Radix Bupleuri 90g, Rhizoma Cyperi 90g, Rhizoma Corydalis 30g, Rhizoma Curcumae 30g, Poria 20g, Sargassum 20g, Rhizoma Pinelliae 20g, Semen Vaccariae 15g, Semen Citri Reticulatae 15g, Radix Puerariae 20 g, Herba Taxilli 20 g, Fructus Corni 20 g, Endothelium Corneum Gigeriae Galli 20 g, Fructus Ligustri Lucidi 10 g, Fructus Crataegi (parched to brown) 10 g.
Preparation method: above medicine is pulverized through ultra micron pulverizer, leaves and takes ultra tiny Chinese medicine powder 390g after removing slag.
Instructions of taking: the medicated powder 13g getting above-mentioned preparation, boiled water 100ml takes after mixing it with water, every day three times.10 days courses for the treatment of.Discontinue medication between per course for the treatment of 1 ~ 2, proceed the treatment of the next course for the treatment of, take more than 2 ~ 3 courses for the treatment of continuously, after disappearing to pain symptom, carry out the treatment of more than 1 course for the treatment of again with medicine of the present invention, after treatment effect also eliminates potential Hypertrophic focus.
Certainly, also tablet, oral liquid or granule can be made, to remove disease misery timely and effectively for more cyclomastopathy patient eventually through pharmaceutical manufacturer's production in enormous quantities.
Be suitable for diseases range: have good effect to the treatment of cyclomastopathy.
Prescription drug effect and mechanism:
Radix Bupleuri: bitter, is slightly cold.Return liver, gallbladder meridian.Effect reconciling superficies and interior, soothing the liver, yang invigorating.
Rhizoma Cyperi: pungent, micro-hardship, micro-sweet, flat, enters liver spleen tri-jiao channel.Effect dispersing the stagnated live-QI to relieve the stagnation of QI, menstruction regulating and pain relieving, regulate the flow of vital energy adjust in.
Rhizoma Corydalis: acrid, bitter, warm.Return liver, spleen, heart channel.Effect is invigorated blood circulation, circulation of qi promoting, pain relieving.
Rhizoma Curcumae: pungent, bitter, temperature.Return liver, spleen channel.Effect removing blood stasis, promoting the circulation of QI to relieve pain.
Poria: sweet in the mouth, light, property are put down, and enter the heart, lung, spleen channel.Effect eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming.
Sargassum: bitter in the mouth, salty, cold.Return lung, stomach, kidney channel.Effect softening the hard mass, expectorant, diuretic, expels the heat-evil.
The Rhizoma Pinelliae: pungent, warm.Return spleen, stomach, lung meridian.Effect drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.
Semen Vaccariae: bitter is flat.Return liver, stomach warp.Effect blood stimulates the menstrual flow, stimulating milk secretion eliminating carbuncle, inducing diuresis for treating stranguria syndrome.
Semen Citri Reticulatae: bitter, flat.Return liver, kidney channel.Effect is regulated the flow of vital energy, eliminating stagnation, pain relieving.
Radix Puerariae: sweet, pungent, cool.Return lung, spleen, stomach warp.Effect is induced sweat and is brought down a fever, and promotes the production of body fluid, rash, yang invigorating.
Herba Taxilli: bitter, sweet, flat.Return liver, kidney channel.Effect wind-damp dispelling, disappear arthralgia pain, liver and kidney tonifying, bone and muscle strengthening, antiabortive effect.
Fructus Corni: sour, puckery, tepor.Return liver, kidney channel.Effect liver and kidney tonifying, essence astringing and desertion stemming.
Endothelium Corneum Gigeriae Galli: sweet is flat.Return spleen, stomach, small intestinal, urinary bladder channel.Effect can promoting digestion and invigorating the stomach, arresting seminal emission.Strengthening the spleen and stomach, controls infantile malnutrition, incontinence of urine.
Fructus Ligustri Lucidi: cool in nature; Sweet in the mouth, hardship; Return kidney, Liver Channel.Effect yin nourishing, nourishing the liver and kidney, improving eyesight black hair.
Fructus Crataegi (parched to brown): acid, sweet, tepor; Return Pi, stomach, Liver Channel.Effect promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis, the meat that disappears are long-pending.
All medicines share above, can play reconciling superficies and interior, soothing the liver yang invigorating, menstruction regulating and pain relieving, regulate the flow of vital energy adjust in, removing blood stasis, eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, enriching yin and nourishing kidney, mind tranquilizing and the heart calming, dissolving lump and resolving mass effect.So good treatment and preventive effect can be played to cyclomastopathy and even its complication.
By to the observation of a large amount of cyclomastopathy patient and analysis, we find, the generation of adult mammary gland cyclomastopathy is relevant with many factors, the traditional Chinese medical science is thought: feelings are smooth, and irritability must not normally be dredged and to be rushed down and qi stagnation blood stasis disease is solidifying, disharmony of Chong and Conception Channels person, often there is menoxenia, facial colour spot.Modern medicine is thought: the external environment of marriage and childbirth, meals, people living and inherited genetic factors are the main causes of mammary gland morbidity.But it is main relevant with endocrine disturbance and Nervous and Mental Factors.Lutein secretion reduces, and estrogen increases relatively, is the major reason of primary disease.Be mainly the hyperplasia of prostate of mammary gland interstitial, hypertrophy can to betide around glandular tube and to be formed with the cyst differed in size; Also the nipple sample hypertrophy showing as epithelium in glandular tube can be occurred in, the cystic dilatation of companion's latex dust.Cyclomastopathy is also known as cystic hyperplasia of breast, belong to the traditional Chinese medical science " nodules of the breast " category, in postpubertal women, incidence rate is higher, according to incompletely statistics, about more than 70% suffers from cyclomastopathy, and in whole cystic hyperplasia of breast, cyclomastopathy accounts for 80%, and some patients are just in premenstrual breast swell and pain, through after disappear, so do not cause enough attention.The lump of cyclomastopathy and pain are outer with breast, top is common, and self-examination can lie flat on the bed, and with forefinger and middle finger concora crush breast and around, whether can contact lump or pain.Can not grab with hands, in order to avoid normal connective tissue is used as lump.Chinese medicine is thought, cyclomastopathy main diseases is at Liver Channel stomach function regulating warp, and pathogenic factor is cold, wet, think of, anger.Treatment emphasis: soothing the liver circulation of qi promoting, blood stasis-eliminating and stagnation-dissipating.Emotion should be put down tuberosity in the heart, One can be austere if he has no selfish desires.In the therapeutic process of cyclomastopathy, we should pay attention to soothing the liver, yang invigorating, menstruction regulating and pain relieving, regulate the flow of vital energy adjust in, removing blood stasis, eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming, dissolving lump and resolving mass.Effectively can be in progress by symptom management like this, and final effect of curing can be reached.Righting uses with getting rid of evils by this formula simultaneously, and the direct cause of disease is eliminated together with the indirect cause of disease, so successful, is the effective Chinese medicine composition of one be worth of widely use.
The invention has the beneficial effects as follows: this Chinese medicine composition both can be used alone treatment cyclomastopathy, also can use with the remedy measures such as " western medicine and medical practitioners is treated ", " traditional Chinese massage is treated ", " Chinese medicine acupuncture is treated ", " scrape therapy is treated ", " cupping for treatment " simultaneously, be characterized in that instant effect, curative effect are reliable, cure rate is high, does not find that there is obvious toxic-side effects.Both can alleviate the state of an illness of cyclomastopathy in a short time, and can complication have been controlled again, improve disease-resistant repair ability.A kind of more effective than remedy measures such as western medicine and medical practitioners and other traditional Chinese medical therapeutic programs, and ideal medicament of being free from side effects.
Below in conjunction with clinical data and model case, beneficial effect of the present invention is further described:
One, clinical observation
1. clinical data: be selected from outpatient's totally 146 examples year November in August, 2012 to 2014 with complete case-data.Be divided into treatment by Chinese herbs group 73 example at random, 26 ~ 56 years old age.Matched group 73 example, at 25 ~ 58 years old age, two groups of ages compare there was no significant difference (p > 0.05).
2. diagnostic criteria: its diagnostic criteria is with reference to the diagnostic criteria about cyclomastopathy in " disease of tcm Standardization of diagnosis and curative effect ".
3. preparation method: above 15 herbal medicines are pulverized through ultra micron pulverizer, leaves and takes ultra tiny Chinese medicine powder 390g after removing slag, seal up for safekeeping.It is amount 1 course for the treatment of (10 days).
4. Therapeutic Method: every day 39g, point morning, noon and afternoon take for three times, and each 13g, takes after mixing it with water with boiled water 100ml, 10 days courses for the treatment of; Discontinue medication between per course for the treatment of 1 ~ 2, proceed the treatment of the next course for the treatment of, take 2 courses for the treatment of or longer continuously.Matched group gives western medicine, and with Tamoxifen Citrate (tamoxifen), each 10mg-20 mg is oral, 2 times/d.Conventional therapy 3 d is 1 course for the treatment of, repeats after continuous application 3d.
5. efficacy assessment standard: efficacy assessment standard is formulated with reference to " disease of tcm Standardization of diagnosis and curative effect ".
Clinical recovery: the transference cures such as distending pain, tenderness, nipple discharge, partial thickening or lump disappear, and can normally work and live.
Effective: the transference cures such as distending pain, tenderness, nipple discharge, partial thickening alleviates or lump diminishes.
Invalid: symptom and sign is without improvement.
6. therapeutic outcome: two groups of therapeutic outcomes are in shown in table 1 and table 2:
Two groups of cure rate synopsis after 10 days treated by table 1
Group Example time Recovery from illness/example Significant figure/example Invalid number/example Total effective rate (%)
Treatment group 73 21 48 4 94.52
Matched group 73 14 39 20 72.60
Through X 2 test, two groups of total effective rates compare, and difference has very significant (P < 0.001).
Two groups of cure rate synopsis after 20 days treated by table 2
Group Example time Recovery from illness/example Significant figure/example Invalid number/example Total effective rate (%)
Treatment group 73 48 25 0 100
Matched group 73 25 38 10 86.30
Through X 2 test, two groups of total effective rates compare, and difference has very significant (P < 0.001).
In a word, while Comprehensive Treatment, utilize and take Drug therapy cyclomastopathy of the present invention and merge cyclomastopathy patient 73 example, total effective rate is up to 94.52% and 100%, far above 72.60% of matched group with the total effective rate of 86.30%, and treatment group all has no side effect .
Two, model case is as follows:
Case 1: king so-and-so, female, 36 years old, right distending pain of the breast 4 days, local scleroma, tenderness.Found by Mammography shows: the outside upper quadrant of right side breast is shown in a lamellar increase in density shadow, and edge owes concrete.Pathology puncture diagnosis right side breast cyclomastopathy.After the application of the invention Drug therapy, after 10 days, symptom obviously alleviates.
Case 2: cattle so-and-so, female, 38 years old, left distending pain of the breast 5 days, local touch enclosed mass, tenderness.Through breast ultrasound, Found by Mammography, cyclomastopathy on the left of binding of pathological puncture diagnosis, the application of the invention Drug therapy after 8 days symptom obviously alleviate, after 20 days, pathological changes is cured substantially.
Case 3: shut out certain, female, 26 years old, right distending pain of the breast 3 days, enclosed mass, tenderness were touched, nipple discharge in local.Found by Mammography binding of pathological puncture diagnosis right side breast cyclomastopathy, the application of the invention Drug therapy is cured for 16 days afterwards substantially.
Case 4: Wang so-and-so, female, 29 years old, right distending pain of the breast 2 days, local touch enclosed mass, tenderness, skin Wen Bugao.Breast ultrasound binding of pathological puncture diagnosis right side breast cyclomastopathy, use Drug therapy of the present invention after 11 days symptom substantially disappear.
Case 5: Wu so-and-so, female, 37 years old, left distending pain of the breast 6 days, local touch enclosed mass, tenderness, skin Wen Bugao.Cyclomastopathy on the left of Found by Mammography binding of pathological puncture diagnosis, use Drug therapy of the present invention after 9 days symptom obviously alleviate, after 18 days, symptom disappears substantially.
Case 6: permitted so-and-so, female, 41 years old ,right side breast distending pain 4 days, shooting breast molybdenum target CR sheet is shown in right breast outside upper quadrant lumps high density shadow, and blur margin is clear, and local skin, without thickening, has no calcification in it.Pathology puncture diagnosis right side breast cyclomastopathy.Take medicine of the present invention after 9 days symptom alleviate, symptom after 2 courses for the treatment of .
detailed description of the invention:
Embodiment 1
Formula: Radix Bupleuri 90g, Rhizoma Cyperi 90g, Rhizoma Corydalis 30g, Rhizoma Curcumae 30g, Poria 20g, Sargassum 20g, Rhizoma Pinelliae 20g, Semen Vaccariae 15g, Semen Citri Reticulatae 15g, Radix Puerariae 20g, Herba Taxilli 20g, Fructus Corni 20g, Endothelium Corneum Gigeriae Galli 20g, Fructus Ligustri Lucidi 10g, Fructus Crataegi (parched to brown) 10g.
Preparation and instructions of taking: above 15 herbal medicines are pressed formula proportion and pulverize through ultra micron pulverizer, leave and take micropowders Chinese medicine powder 390g after removing slag, sealing up for safekeeping is 10 feed rations.According to dose 39g on the 1st, get 13g at every turn, take after mixing it with water with 100 milliliters of boiled water, point three morning, noon and afternoon take.It within 10th, is a course for the treatment of.The non-complete incidence graph person of symptom, can terminate rear drug withdrawal 1 ~ 2 day the course for the treatment of, proceeds the treatment of the next course for the treatment of, takes 2 ~ 3 courses for the treatment of continuously, to transference cure, then carry out the treatment of more than 1 course for the treatment of with medicine of the present invention, with after treatment effect.

Claims (1)

1. treat a Chinese medicine composition for cyclomastopathy, it is characterized in that, it is made up of the crude drug of following weight portion: Radix Bupleuri 90 parts, Rhizoma Cyperi 90 parts, Rhizoma Corydalis 30 parts, Rhizoma Curcumae 30 parts, 20 parts, Poria, Sargassum 20 parts, the Rhizoma Pinelliae 20 parts, Semen Vaccariae 15 parts, Semen Citri Reticulatae 15 parts, Radix Puerariae 20 parts, Herba Taxilli 20 parts, Fructus Corni 20 parts, Endothelium Corneum Gigeriae Galli 20 parts, Fructus Ligustri Lucidi 10 parts, Fructus Crataegi (parched to brown) 10 parts.
CN201510057492.2A 2015-02-04 2015-02-04 Traditional Chinese medicine composition for treating hyperplasia of mammary glands Pending CN104689229A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105454579A (en) * 2015-12-11 2016-04-06 靖州苗族侗族自治县科技推广中心 Health tea capable of preventing breast cancer and preparation method of health tea

Citations (1)

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Publication number Priority date Publication date Assignee Title
CN102988889A (en) * 2012-11-22 2013-03-27 王雪娟 Traditional Chinese medicine composition for treating hyperplasia of mammary glands

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
CN102988889A (en) * 2012-11-22 2013-03-27 王雪娟 Traditional Chinese medicine composition for treating hyperplasia of mammary glands

Non-Patent Citations (1)

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Title
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105454579A (en) * 2015-12-11 2016-04-06 靖州苗族侗族自治县科技推广中心 Health tea capable of preventing breast cancer and preparation method of health tea

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Application publication date: 20150610