CN104688337B - A kind of laser therapeutic system of ablation of tissue - Google Patents
A kind of laser therapeutic system of ablation of tissue Download PDFInfo
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- CN104688337B CN104688337B CN201510054703.7A CN201510054703A CN104688337B CN 104688337 B CN104688337 B CN 104688337B CN 201510054703 A CN201510054703 A CN 201510054703A CN 104688337 B CN104688337 B CN 104688337B
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Abstract
The invention discloses a kind of laser therapeutic system of ablation of tissue, and it includes medical switching device, man-machine interaction display device, main control unit, medical semiconductor laser device drive module, medical semiconductor laser device module, medical semiconductor laser device temperature control device, heat abstractor 1, heat abstractor 2, the joints of optical fibre and Minimally Invasive Surgery optical fiber component.The medical semiconductor laser device module includes first laser device assembly and second laser device assembly；The first laser is different with the wavelength of the second laser；The first laser is the visible wavelength lasers for indicating irradiation area, and the second laser is the eye-safe IR wavelength laser for fat melting, the absorptivity for having higher water and fat.
Description
Technical field
The invention belongs to medical Instrument field, and in particular to a kind of laser therapeutic system of ablation of tissue, for human body
The safe ablation of fat deposit.
Background technology
With the continuous improvement of people's living standards, the change of dietary structure, the fast pace life of high pressure is more and more
People perplexed by problem of obesity, fat-reducing market is increasingly huge, and people are constantly studied by various means, explores various minimally invasive subtract
The method of fertile fat melting.At present, minimally invasive fat melting ways of preventing obesity mainly has injection fat melting, ultrasonic fat melting, conventional laser fat melting.
The principle for injecting fat melting weight reducing treatments is based on mesoderm is treated, by the liquid containing slimming ingredient with pin
Form, the subcutaneous layer of fat of direct injection human body, subcutaneous fat is dissolved.When medicine passes through hypodermis, local fat is stimulated
The intracellular lipase quantity increase of fat, and the activation of stimulating protein, change into the intracellular sweet triphosphoric acid of deoxidation core de-
Oxygen nucleic acid, promote to refer to the activation of fat and increase cut-out aliphatic acid, it is resolved into compact state, be metabolized with the new battle array of body
Excreted by lymphatic system.But injection fat melting also has the disadvantage that, because drug dose control is possible to cause tubercle sense
The adverse reaction such as dye and nausea, it is also possible to different degrees of subcutaneous hemorrhage, ecchymosis, yellow subcutaneous ulcer, skin ulcer etc. occur.
Ultrasound is due to its good directionality, the advantages that penetration capacity is strong, has a wide range of application.The principle of wherein ultrasonic fat melting is logical
Cross a kind of magnetic transducer or piezo-electric crystal and convert electrical energy into mechanical energy.Over the course for the treatment of, pop one's head in and sent necessarily subcutaneous
The ultrasonic wave of frequency and energy, mechanical effect, cavitation, magnificent school should act on biological tissue, moment simultaneously with fuel factor
Making the microbubble in adipose tissue, acutely expansion up to rupture, so as to thoroughly destroy adipocyte structure, is allowed to broken, is disintegrated,
And stimulate adipocyte to discharge lipid therein on the premise of adipocyte plasma membrane is not destroyed, adipocyte volume is reduced, most
The adipocyte after emulsification is pumped out by vacuum sliding chute equipment afterwards.Although ultrasonic wave liposuction has good effect, but super
The incidence of the complication such as fire damage, postoperative seroma and skin burn caused by fuel factor is higher in sound fat melting art, and not
The shank position more suitable for the engraving of local slight part, particularly face, neck, back, muscle composition.
Laser lipolysis can be applied not only to belly, waist, leg, buttocks, more be particularly adapted to arm, face
Portion, the tiny local fine position of the relatively thin extremely difficult fat reducing by other means of the such fat deposit of neck.Its uniqueness of laser lipolysis
Fat liquor carries out comprehensive liquefaction to fat, and while dissolved fat, the fatty dissolution dissolving is external, hence it is evident that adds
The discharge rate of pure fat.Laser is only acted on the fat deposit of setting used by laser lipolysis art, does not injure epidermis skin not only,
Self-regeneration, the stimulation collagen hyperplasia of elastic fibers of skin can also be accelerated, allow the skin for being drawn through fat still to keep compacting,
It is smooth, open and flat.
Conventional laser fat melting uses single laser, and optical fiber used is untapered optical fiber, and the laser output of this optical fiber has
Linearity and indiffusion, local temperature may be too high, and the light angle of laser, which produces slight deviations, may cause burning for skin
The defects of hindering.
The content of the invention
To overcome deficiency of the prior art, " laser therapeutic system of ablation of tissue " of the invention to be researched and developed, using double
Lasing light emitter transmitter, and comprehensive monitoring and accurate control are carried out to whole therapeutic process, safely and efficiently controlled so as to realize
Treat.
In order to solve the above-mentioned technical problem, above-mentioned purpose is realized, the present invention is achieved through the following technical solutions：
A kind of laser therapeutic system of ablation of tissue, including medical switching device, man-machine interaction display device, main control dress
Put, medical semiconductor laser device drive module, medical semiconductor laser device module, medical semiconductor laser device temperature control device, dissipate
Thermal, the joints of optical fibre and Minimally Invasive Surgery optical fiber component.
The main control unit, for controlling medical semiconductor laser device module to export swashing for corresponding modes according to setting
Light, output display and the storage of related data are completed, be responsible for touch-screen driving, complete the response of touch screen signal, and by power
Setting is dealt into medical semiconductor laser device drive module；
The medical semiconductor laser device drive module：Using FPGA as control core, serial ports association is carried out with single-chip microcomputer
View parsing, there are output short-circuit, the defencive function such as open circuit detection, electrostatic protection；
The medical semiconductor laser device module：For producing laser and output laser, the module includes two laser
Device assembly, the heat sink of radiating, light-integrating subassembly and fiber coupling interface, the exportable visible wavelength and use for being used to indicate irradiation area
In two kinds of laser of infrared wavelength of fat melting.
The Minimally Invasive Surgery optical fiber component is connected the production of output laser module by the joints of optical fibre with fiber coupling interface
Raw laser, using Plasma-Laser export technique, make laser in optical fiber connector with 360 degree of spherical plasma fiber exits.
The medical semiconductor laser device temperature control device is used to accurately control laser temperature under finite size
System, and by laser module export caused by heat caused by heat and temperature control take the device of system out of.
The heat abstractor is two, the first heat abstractor with the medical semiconductor laser device module is heat sink contacts, it is logical
Cross air cooling way cooling；Second heat abstractor and the medical switching device, medical semiconductor laser device drive module, medical half
Conductor laser temperature control device contacts, and is cooled down by air cooling way.
In one embodiment, the IR wavelength laser device assembly for fat melting, including two beams can independent control
Laser, and ablation of tissue is carried out by the joints of two beam laser, and per beam of laser to the tissue regions irradiated without obvious
Damage.
In one embodiment, the IR wavelength laser device assembly for fat melting, its optical maser wavelength launched are
1470nm, the power selection scope per Shu Jiguang is 0-12W.
In one embodiment, the man-machine interaction display device, including display to body local region it is infrared heat into
As stereogram, and ablation of tissue point is tracked.
In one embodiment, the main control unit disappears according to the infrared thermal imaging situation in body local region to tissue
Melting point carries out temperature monitoring, and the angle of at least one laser beam is adjusted if temperature exceedes the threshold value of setting.
The laser of the present invention two wavelength of output, using Plasma-Laser export technique, makes laser in optical fiber connector with 360
Spend spherical plasma fiber exit.Spherical light is easily-controllable, and photo-thermal temperature is uniform, is not easy to be carbonized, and does not damage other tissues；Utilize
Fibre optical transmission laser of the diameter less than 1 millimeter enters fat deposit, can accurately sketch the contours tiny local fine position, it is whole to reach microscopic carvings
The effect of shape.
The present invention use fat melting laser assembly, include two beams can independent control laser, pass through ablation a side
Formula, the accurate ablation of safety is carried out to tissue.
Further, since the wave band of selection has high water absorptivity, glue can be made by heat effect in the moment for the treatment of
The restructuring of former albumin layer and have the function that firm skin, make shallow fat deposit fat melting process more rapidly, it is smooth, safe,
The skin for being drawn through fat is allowed still to keep compacting, be smooth, open and flat.
Brief description of the drawings
Accompanying drawing described herein is used for providing a further understanding of the present invention, forms the part of the application, this hair
Bright schematic description and description is used to explain the present invention, does not form inappropriate limitation of the present invention.In the accompanying drawings：
Fig. 1 is the system structure diagram of the present invention.
Embodiment
The technology implementation process of the present invention is described further with reference to the accompanying drawings and examples.
A kind of laser therapeutic system of ablation of tissue, it includes medical switching device, man-machine interaction display device, main control
Device, medical semiconductor laser device drive module, medical semiconductor laser device module, medical semiconductor laser device temperature control device,
Heat abstractor 1, heat abstractor 2, the joints of optical fibre and Minimally Invasive Surgery optical fiber component.It is characterized in that：
Medical switching device：For 220V input ac voltage to be converted into the available direct voltage output of each module；
Man-machine interaction display device：Microprocessor is communicated with display device by RS232 and controls its display interface
And output relevant information, while obtain correlated inputs and data are set；
Main control unit：It is complete for controlling laser of the medical semiconductor laser device module according to setting output corresponding modes
Output display and storage into related data, it is responsible for touch-screen driving, completes the response of touch screen signal, and power setting is sent out
To medical semiconductor laser device drive module；
Medical semiconductor laser device drive module：Using FPGA as control core, serial port protocol solution is carried out with single-chip microcomputer
Analysis, there are output short-circuit, the defencive function such as open circuit detection, electrostatic protection；
Medical semiconductor laser device module：For producing laser and output laser, the module includes two laser groups
Part, the heat sink of radiating, light-integrating subassembly and fiber coupling interface, it is exportable to be used to indicate the visible wavelength of irradiation area and for molten
Two kinds of laser of infrared wavelength of fat；
Medical semiconductor laser device temperature control device：For more accurate control to be carried out to laser temperature under finite size
System, and by laser module export caused by heat caused by heat and temperature control take the device of system out of；
Heat abstractor 1：With the medical semiconductor laser device module is heat sink contacts, mode of laser is cooled down by air cooling way
Block；
Heat abstractor 2：With the medical switching device, medical semiconductor laser device drive module, medical semiconductor laser
Device temperature control device is contacted, and contacted modules are cooled down by air cooling way；
Minimally Invasive Surgery optical fiber component and the joints of optical fibre：Minimally Invasive Surgery optical fiber component passes through the joints of optical fibre and fiber coupling
Laser caused by interface connection output laser module, using Plasma-Laser export technique, makes laser in optical fiber connector with 360
Spherical plasma fiber exit is spent, spherical light is easily-controllable, and photo-thermal temperature is uniform, is not easy to be carbonized, and does not damage other tissues；
Two laser assemblies are first laser device assembly and second laser device assembly respectively；
First laser device assembly is used to send first laser, and the second laser device assembly is used to send second laser, its
In, the first laser is the visible wavelength lasers for indicating irradiation area, and the second laser is the human eye for fat melting
Safe IR wavelength laser, there is the wavelength of the absorptivity of higher water and fat, the first laser and the second laser
Difference, the laser of two different wave lengths merge into beam of laser to fiber coupling interface through light-integrating subassembly.
First laser wavelength is 650nm, and second laser wavelength is 1470nm.First laser is continuous mode laser；It is described
Second laser is one kind continuously, in modulation pulse mode laser.Second laser has continuous and modulation two kinds of output modes of pulse,
Modulation pulse mode is pulse width and frequency-adjustable, and wherein pulse width modulation scope is 20ms-1000ms, and frequency adjusts model
It is 1-50Hz to enclose.
In one embodiment, the second IR wavelength laser device assembly for fat melting, including two beams can independently control
The laser of system, and ablation of tissue is carried out by the joints of two beam laser, and per beam of laser to the tissue regions that are irradiated without
Obvious damage.
In one embodiment, the second IR wavelength laser device assembly for fat melting, its optical maser wavelength launched
For 1470nm, the power selection scope per Shu Jiguang is 0-12W.
In one embodiment, the man-machine interaction display device, in addition to display is to the infrared heat in body local region
Imaging volume figure, and ablation of tissue point is tracked.
In one embodiment, the main control unit disappears according to the infrared thermal imaging situation in body local region to tissue
Melting point carries out temperature monitoring, the angle of adjust automatically at least one laser beam if temperature exceedes the threshold value of setting.
Heat abstractor 1, including semiconductor chilling plate, radiator, fan, the cold end of semiconductor chilling plate and medical semiconductor
Laser module is heat sink to be contacted by heat-conducting silicone grease；The hot junction of semiconductor chilling plate is contacted by indium foil with radiator, radiator
Increment side fan attachment.Semiconductor chilling plate controls its operating current voltage by medical semiconductor laser device temperature control device.
Minimally Invasive Surgery optical fiber component includes fiber operation handle and operation optical fiber, and operation optical fiber inserts fiber operation handle,
The other end connection joints of optical fibre of fiber operation handle, the other end for optical fiber of performing the operation is 360 degree of spherical plasma optical fiber.
System utilizes 360 degree of spherical plasma fiber exit laser beams, and spherical light is easily-controllable, and photo-thermal temperature is uniform, no
Easily carbonization, does not damage other tissues, can accurately sketch the contours tiny local fine position, reach the effect of microscopic carvings shaping；Due to choosing
The wave band selected has high water absorptivity, by heat effect collagen layer restructuring can be made to reach tight in the moment for the treatment of
Cause the effect of skin, make shallow fat deposit fat melting process more rapidly, it is smooth, safe, allow and be drawn through fatty skin still
Holding is compacted, is smooth, be open and flat.
After employing plasma optical fiber, traditional light beam heating region is changed, forms spherical heating so that heterogeneity phantom
Evenly, photo-thermal temperature is uniform and stable, and the angle of divergence of light is in 360 degree, and laser energy is more concentrated, and effect or speed are about that tradition swashs
5-10 times of light fat melting.Spherical light can produce higher heat than general laser, dissolve more fat, while reduce and control
Overheat risk in treatment, reduces the generation of side effect；Spherical size can be controlled by changing parameter, carry out different parts
Fat melting；Spherical light is easily controlled, and does not damage other tissues.
Whether medical semiconductor laser device module sends laser, or sends continuous laser or pulse laser, including output
The power of laser, pulse width and frequency, it can be controlled by main control unit.Main control unit is according to human-computer interaction interface
The data of input and instruction, control medical semiconductor laser device drive module into medical semiconductor laser device module first swash
Light device assembly and second laser device assembly output driving current, make first laser device assembly and second laser device assembly send it is sharp
Light.First laser is the visible wavelength lasers for indicating irradiation area, continuous mode laser is exported according to setting, when man-machine friendship
Mutual interface by it is standby switch to SBR when, the laser driven power supply output of main control unit control first laser component is continuous
Electric current.First laser is continuously exported, persistently illuminate the microscopic carvings shaping region in front of 360 degree of spherical operation optical fiber connectors.Second
Laser is the IR wavelength laser for microscopic carvings shaping, can work as people according to setting output continuously with modulation pulse mode laser
When machine interactive interface have selected continuous mode and perform, main control unit is to control the laser driven power supply of second laser component defeated
Go out continuous current, second laser is continuously exported, the microscopic carvings shaping region in front of the spherical operation optical fiber connector of 360 degree of prolonged exposure
Domain；When human-computer interaction interface have selected modulation pulse mode and perform, main control unit is to control swashing for second laser component
Pulse width and rate-adaptive pacemaker the modulation electric current that optical drive power supply is set according to human-computer interaction interface, make second laser continuously export
Modulate laser, 360 degree of prolonged exposure it is spherical operation optical fiber connector in front of microscopic carvings shaping region.Second laser output simultaneously by
The control of floor push, exported when stepping on floor push, stop output when lifting floor push.
Alarm condition：
When the Interlock remote interlock connectors of system disconnect, the output of the first and second laser can be now cut off,
And in human-computer interaction interface display alarm information；
When system the joints of optical fibre not in contact with it is good when, the output of the first and second laser can be now cut off, and in man-machine friendship
Mutual interface display warning message；
When system second laser power output deviation is more than 20%, the output of the first and second laser can be now cut off, and
In human-computer interaction interface display alarm information；
When instrument internal temperature is too high, the output of the first and second laser can be now cut off, and show in human-computer interaction interface
Show warning message；
When pulse width deviation is more than 20%, the output of the first and second laser can be now cut off, and in man-machine interaction circle
Face display alarm information.
1470nm semiconductor laser wavelength features
1470nm semiconductor laser wavelengths have the water and fat that more times are higher by than conventional 1320nm, 980nm, 1064nm wavelength
Fat absorptivity, and fat melting most pronounced effects, 1470nm can accelerate fat emulsification, the damage to outside organization by low-power
It is small, it is safer.The laser of other wavelength then needs higher energy to go to accelerate fat emulsification.Also, high water absorption coefficient
By heat effect collagen layer restructuring can be made to have the function that firm skin in the moment for the treatment of.
The photothermolysis principle of laser, laser beam is selectively melted to the cell membrane of adipocyte, so as to cause fat
Rupture liquefaction, really reduces fatty quantity, and laser with 360 degree of spherical beam projectings, makes laser energy more concentrate in optical fiber connector,
Fat melting speed is 10 times of traditional line propagated laser fat melting speed, and spherical light is easily controlled, and does not damage other tissues.
Tissue by laser can produce heat, light, chemical effect and biostimulation, laser therapeutic apparantus during laser microscopic carvings shaping
Laser energy is discharged, the cell membrane of adipocyte is selectively melted by the fuel factor of laser, so as to cause fat rupture liquefaction,
Adipocyte number is reduced, and laser, with 360 degree of spherical beam projectings, makes laser energy more concentrate, microscopic carvings shaping in optical fiber connector
Speed is 10 times of traditional line propagated laser microscopic carvings shaping speed, and spherical light is easily controlled, and does not damage other tissues.Melt
Thawing fat can be discharged with the mode that extruding or syringe aspirate by changing the less position of fatty area.In addition, laser microscopic carvings are whole
The energy discharged during shape can stimulate the collagen hyperplasia of skin, and the skin after elimination fat is become consolidation song
Line.
The preferred embodiments of the present invention are the foregoing is only, are not intended to limit the invention, for the skill of this area
For art personnel, the present invention can have various modifications and variations.Within the spirit and principles of the invention, that is made any repaiies
Change, equivalent substitution, improvement etc., should be included in the scope of the protection.
Claims (1)
- A kind of 1. laser therapeutic system of ablation of tissue, it is characterised in that：The system includes medical switching device, man-machine interaction shows Showing device, main control unit, medical semiconductor laser device drive module, medical semiconductor laser device module, medical semiconductor swash Light device temperature control device, heat abstractor, the joints of optical fibre and Minimally Invasive Surgery optical fiber component；The main control unit, cured for controlling The laser of corresponding modes is exported according to setting with semiconductor laser module, completes output display and the storage of related data, is born Blame touch-screen driving, complete the response of touch screen signal, and power setting is dealt into medical semiconductor laser device drive module；The medical semiconductor laser device drive module：Using FPGA as control core, serial port protocol solution is carried out with single-chip microcomputer Analysis, there are output short-circuit, open circuit detection, electrostatic protection defencive function；The medical semiconductor laser device module：For producing laser and output laser, the medical semiconductor laser device module Including two laser assemblies, the heat sink of radiating, light-integrating subassembly and fiber coupling interface, described two laser assembly outputs are used Visible wavelength in instruction irradiation area and two kinds of laser of infrared wavelength for fat melting, i.e. first laser and second laser；Institute State Minimally Invasive Surgery optical fiber component and be connected the output medical semiconductor laser device mould with fiber coupling interface by the joints of optical fibre Laser caused by block, using Plasma-Laser export technique, laser is set to go out in optical fiber connector with 360 degree of spherical plasma optical fiber Penetrate；The medical semiconductor laser device temperature control device is used to be accurately controlled laser temperature under finite size, and Take heat caused by heat caused by medical semiconductor laser device module output and temperature control out of system；The radiating Device is two, the first heat abstractor with the medical semiconductor laser device module is heat sink contacts, cooled down by air cooling way；The Two heat abstractors fill with the medical switching device, medical semiconductor laser device drive module, the temperature control of medical semiconductor laser device Contact is put, is cooled down by air cooling way；For the IR wavelength laser device assembly of fat melting, include two beams can independent control swash Light, and ablation of tissue is carried out by the joint of two beam laser, and the tissue regions irradiated are damaged without obvious per beam of laser Wound；The IR wavelength laser device assembly for fat melting, its optical maser wavelength launched is 1470nm, and the power per Shu Jiguang selects It is 0-12W to select scope；The man-machine interaction display device, including the infrared thermal imaging stereogram to body local region is shown, And ablation of tissue point is tracked；The main control unit disappears according to the infrared thermal imaging situation in body local region to tissue Melting point carries out temperature monitoring, the angle of adjust automatically at least one laser beam if temperature exceedes the threshold value of setting；When system When Interlock remote interlock connectors disconnect, first laser and second laser output can be now cut off, and show in man-machine interaction Showing device display alarm information；When system the joints of optical fibre not in contact with it is good when, first laser and second laser output can be now cut off, and in man-machine friendship Mutual display device display alarm information；When system second laser power output deviation is more than 20%, first laser and second laser output can be now cut off, and In man-machine interaction display device display alarm information；When instrument internal temperature is too high, first laser and second laser output can be now cut off, and show and fill in man-machine interaction Put display alarm information；When pulse width deviation is more than 20%, first laser and second laser output can be now cut off, and show in man-machine interaction Showing device display alarm information.
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| WO2018072610A1 (en) * | 2016-10-17 | 2018-04-26 | 西安炬光科技股份有限公司 | Semiconductor laser module and method for application in noninvasive medical treatment |
| CN108283521B (en) * | 2017-11-29 | 2021-08-06 | 北京华夏光谷光电科技有限公司 | Laser body surface acoustic/laser intra-abdominal molten fat composite type weight losing device |
| CN108836477B (en) * | 2018-05-14 | 2021-05-11 | 华科精准（北京）医疗科技有限公司 | Laser thermotherapy device and system based on magnetic resonance guidance |
| CN109567933B (en) * | 2018-12-07 | 2021-08-06 | 中聚科技股份有限公司 | Double-optical fiber laser treatment device |
| CN109893770B (en) * | 2019-04-02 | 2020-08-18 | 西安交通大学 | Laser fat dissolving system with coupled laser fat dissolving, skin surface temperature measurement and spray cooling |
| CN111000628A (en) * | 2019-11-18 | 2020-04-14 | 武汉戴美激光科技有限公司 | Temperature monitoring device and method for laser surgery |
| CN111672034B (en) * | 2020-04-26 | 2022-06-14 | 上海盼研机器人科技有限公司 | Ultrasonic fat dissolving robot |
| CN111600179A (en) * | 2020-05-25 | 2020-08-28 | 中国人民解放军总医院 | 266nm laser treatment equipment |
| CN112618013B (en) * | 2021-02-10 | 2022-03-08 | 福建师范大学 | Photo-thermal treatment system based on temperature and image dual-mode monitoring and feedback |
| CN117064315A (en) * | 2023-09-11 | 2023-11-17 | 显微智能科技(湖南)有限公司 | Endoscope light source linkage control device |
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