CN104688239A - Method and system for determining categories of sleep-related breathing events - Google Patents

Method and system for determining categories of sleep-related breathing events Download PDF

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CN104688239A
CN104688239A CN201510137580.3A CN201510137580A CN104688239A CN 104688239 A CN104688239 A CN 104688239A CN 201510137580 A CN201510137580 A CN 201510137580A CN 104688239 A CN104688239 A CN 104688239A
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sleep
patient
respiratory event
respiratory
amplitude
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CN104688239B (en
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李坤
庄志
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Beijing Delightful Harmony Jia Ye Medical Science And Technology Co Ltd
BMC Medical Co Ltd
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Beijing Delightful Harmony Jia Ye Medical Science And Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/103Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
    • A61B5/113Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb occurring during breathing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4806Sleep evaluation
    • A61B5/4818Sleep apnoea

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Abstract

The invention discloses a method and a system for determining categories of sleep-related breathing events. The method includes acquiring chest breathing movement waveforms and abdominal breathing movement waveforms of patients; superimposing the chest breathing movement waveforms and the abdominal breathing movement waveforms to obtain superimposed waveforms; determining the categories of the sleep-related breathing events according to the superimposed waveforms when sleep-related breathing events of the patients occur. The method and the system for determining the categories of the sleep-related breathing events have the advantages that the superimposed waveforms of the chest breathing movement waveforms and the abdominal breathing movement waveforms of the patients are used as determination standards for determining the categories of the sleep-related breathing events, the determination standards are unaffected by air leakage of air channels, accordingly, the categories of the sleep-related breathing events can be accurately determined, accurate bases can be provided for regulating treatment pressures of positive-pressure ventilation treatment apparatuses, treatment effects and the treatment compliance can be greatly improved for the patients, and the use experience of the patients can be obviously improved.

Description

The determination method and system of the kind of sleep-respiratory event
Technical field
The present invention relates to technical field of medical instruments, particularly relate to a kind of defining method of kind of sleep-respiratory event, also relate to a kind of certainty annuity of kind of sleep-respiratory event.
Background technology
Sleep apnea low-ventilatory syndrome, refer to apnea low recurrent exerbation more than 30 times or apnea hypopnea indexes (AHI, Apnea Hypopnea Index) >=5 time/hour with the clinical symptoms such as drowsiness in sleep procedure every night.Asphyxia refers to breathe between sleep period and temporarily stops, showing as that respiratory air flow drops to eupnea amplitude less than 10%, continued at least 10 seconds; Low ventilation refers to that between sleep period, respiratory air flow drops to less than 50% of eupnea amplitude, continues at least 10 seconds, and with blood oxygen saturation comparatively foundation level decline >=4% or microarousal.Apnea and low ventilation event all belong to sleep-respiratory event.Repeatedly there is sleep apnea phenomenon during sleep, easily cause brain, blood severe depletion of oxygen, form hypoxemia, and bring out hypertension, brain cardiopathia, arrhythmia, myocardial infarction, angina pectoris, and then bring out the disease of the multiple system of human body.
In the non-operative treatment means of current treatment sleep apnea low-ventilatory syndrome, the adaptability of continuous positive pressure breathing machine is comparatively wide, uses comparatively common.The base therapy principle of continuous positive pressure breathing machine is, by applying a suitable gas pressure continued to the epithelium healing of patient, the asphyxia symptom of releasing or reduction of patient, to prevent Airway Collapse in sleep, improving water flood structure, hypoxia at night and daytime drowsiness's situation, improve patient sleeps's quality.
At present in positive airway pressure machine, by airflow signal, the method for the most frequently used identification of breathing suspending event or low ventilation event is for judge whether patient there occurs apnea or low ventilation event.The cardinal principle of the method is: the variations in flow using gas flow sensor monitoring positive airway pressure machine gas outlet place.When variations in flow amplitude is less than default asphyxia threshold value and continues preset duration, determine that patient there occurs apnea.When variations in flow amplitude is less than default low ventilation threshold and continues preset duration, determine that patient there occurs low ventilation event.
Above-mentioned recognition methods judges asphyxia or low ventilation by airflow signal, and the method is easily by the impact of positive airway pressure machine blowby gas path.Particularly, when patient's eupnea, the air leakage of therapy apparatus gas circuit is comparatively large, monitors variations in flow amplitude less than normal, now may occur the erroneous judgement of apnea or low ventilation event at positive airway pressure machine gas outlet place.During apnea or low ventilation occur patient, the air leakage of therapy apparatus gas circuit changes, then be likely identified as eupnea, thus causes failing to judge of apnea or low ventilation event.
For the positive airway pressure machine supporting automatic Regulation function, when patient there occurs apnea or low ventilation event, treatment pressure increases.When patient continues eupnea, treatment pressure reduces.But failing to judge and judging the mistake adjustment of the treatment pressure all likely causing positive airway pressure machine to export by accident of apnea or low ventilation event, affects the therapeutic effect of patient.
Summary of the invention
Technical problem to be solved by this invention is: the method detecting apnea or low ventilation event according to airflow signal in prior art is subject to the impact of blowby gas path, probably cause the erroneous judgement of apnea or low ventilation event or fail to judge, thus the adjustment of the mistake of the treatment pressure that positive airway pressure machine may be caused to export, affect the therapeutic effect of patient.
In order to solve the problems of the technologies described above, the invention provides a kind of determination method and system of kind of sleep-respiratory event.
According to an aspect of the present invention, provide a kind of defining method of kind of sleep-respiratory event, it comprises:
Obtain respiratory chest motion waveform and the abdominal respiration moving wave shape of patient;
Described respiratory chest motion waveform and described abdominal respiration moving wave shape are superposed, obtains overlaid waveforms;
When sleep-respiratory event occurs described patient, determine the kind of described sleep-respiratory event according to described overlaid waveforms.
Preferably, the method comprises:
According to the overlaid waveforms amplitude threshold preset and described overlaid waveforms, determine whether described patient there occurs sleep-respiratory event.
Preferably, according to the overlaid waveforms amplitude threshold preset and described overlaid waveforms, determine whether described patient there occurs sleep-respiratory event, comprising:
Calculate the amplitude of the overlaid waveforms of a nearest breathing cycle of described patient;
According to described amplitude and described overlaid waveforms amplitude threshold, judge whether described patient there occurs accurate sleep-respiratory event;
When judging that described patient there occurs accurate sleep-respiratory event, judge whether described accurate sleep-respiratory event maintains the scheduled time;
When judging that described accurate sleep-respiratory event maintains the scheduled time, determine that described patient there occurs sleep-respiratory event.
Preferably, determine the kind of described sleep-respiratory event according to described overlaid waveforms, comprising:
The kind of described sleep-respiratory event is determined according to preset rules;
Wherein, described overlaid waveforms amplitude threshold is determined according to described preset rules.
Preferably, when the kind determining described sleep-respiratory event is asphyxia type, described method also comprises:
Calculate the amplitude that the respiratory chest motion waveform during asphyxia type sleep-respiratory event occurs described patient, obtain thoracic breathing amplitude;
According to thoracic breathing amplitude threshold value and described thoracic breathing amplitude, determine the kind of asphyxia type sleep-respiratory event; Wherein, described thoracic breathing amplitude threshold value is determined according to the respiratory chest motion waveform of patient in nearest scheduled time slot; Or
Calculate the amplitude that the abdominal respiration moving wave shape during asphyxia type sleep-respiratory event occurs described patient, obtain abdominal breathing amplitude;
According to abdominal breathing amplitude threshold value and described abdominal breathing amplitude, determine the kind of asphyxia type sleep-respiratory event; Wherein, described abdominal breathing amplitude threshold value is determined according to the abdominal respiration moving wave shape of patient in nearest scheduled time slot.
According to another aspect of the present invention, provide a kind of certainty annuity of kind of sleep-respiratory event, it comprises:
Respiratory movement waveform acquisition module, is set to the respiratory chest motion waveform and the abdominal respiration moving wave shape that obtain patient;
Addition of waveforms module, is set to superpose described respiratory chest motion waveform and described abdominal respiration moving wave shape, obtains overlaid waveforms;
First kind determination module, is set to, when sleep-respiratory event occurs described patient, determine the kind of described sleep-respiratory event according to described overlaid waveforms.
Preferably, described system also comprises:
Sleep-respiratory event determination module, being set to the overlaid waveforms amplitude threshold according to presetting and described overlaid waveforms, determining whether described patient there occurs sleep-respiratory event.
Preferably, described sleep-respiratory event determination module comprises:
Magnitude computation unit, is set to the amplitude of the overlaid waveforms of the nearest breathing cycle calculating described patient;
First judging unit, is set to, according to described amplitude and described overlaid waveforms amplitude threshold, judge whether described patient there occurs accurate sleep-respiratory event;
Second judging unit, is set to when described first judging unit judges that described patient there occurs accurate sleep-respiratory event, judges whether described accurate sleep-respiratory event maintains the scheduled time;
Determining unit, is set to, when described second judging unit judges that described accurate sleep-respiratory event maintains the scheduled time, determine that described patient there occurs sleep-respiratory event.
Preferably, described first kind determination module is specifically set to: when sleep-respiratory event occurs described patient, determines the kind of described sleep-respiratory event according to preset rules; Wherein, described overlaid waveforms amplitude threshold is determined according to described preset rules.
Preferably, described system also comprises:
Thoracic breathing amplitude determination module, is set to calculate the amplitude that the respiratory chest motion waveform during asphyxia type sleep-respiratory event occurs described patient, obtains thoracic breathing amplitude;
Second kind determination module, is set to, according to thoracic breathing amplitude threshold value and described thoracic breathing amplitude, determine the kind of asphyxia type sleep-respiratory event; Wherein, described thoracic breathing amplitude threshold value is determined according to the respiratory chest motion waveform of patient in nearest scheduled time slot; Or
Abdominal breathing amplitude determination module, is set to calculate the amplitude that the abdominal respiration moving wave shape during asphyxia type sleep-respiratory event occurs described patient, obtains abdominal breathing amplitude;
The third class determination module, is set to, according to abdominal breathing amplitude threshold value and described abdominal breathing amplitude, determine the kind of asphyxia type sleep-respiratory event; Wherein, described abdominal breathing amplitude threshold value is determined according to the abdominal respiration moving wave shape of patient in nearest scheduled time slot.
Compared with prior art, the one or more embodiments in such scheme can have the following advantages or beneficial effect by tool:
The defining method of the kind of the sleep-respiratory event that the application embodiment of the present invention provides, using the respiratory chest motion waveform of patient and the overlaid waveforms of abdominal respiration moving wave shape as the confirmed standard of kind determining sleep-respiratory event, because this confirmed standard is not by the impact of blowby gas path, therefore, it is possible to determine the kind of sleep-respiratory event like clockwork, and then be that the treatment pressure adjusting positive airway pressure machine provides accurate foundation, substantially increase the therapeutic effect of patient and the compliance for the treatment of, significantly improve the experience of patient.
Other features and advantages of the present invention will be set forth in the following description, and partly become apparent from description, or understand by implementing the present invention.Object of the present invention and other advantages realize by structure specifically noted in description, claims and accompanying drawing and obtain.
Accompanying drawing explanation
Accompanying drawing is used to provide a further understanding of the present invention, and forms a part for description, with embodiments of the invention jointly for explaining the present invention, is not construed as limiting the invention.In the accompanying drawings:
Fig. 1 shows the schematic flow sheet of the defining method of the kind of embodiment of the present invention sleep-respiratory event;
Fig. 2 a to Fig. 2 d sequentially show the schematic diagram of the overlaid waveforms after respiratory chest motion waveform, abdominal respiration moving wave shape and the thorax abdomen respiratory movement addition of waveforms when patient is in eupnea state, maincenter type breathing from suspending state, obstructive type breathing from suspending state and low aeration status;
Fig. 3 shows in the embodiment of the present invention and determines whether patient there occurs the schematic flow sheet of the method for sleep-respiratory event;
Fig. 4 to show in the embodiment of the present invention after determining that the kind of sleep-respiratory event is asphyxia type, determines a kind of schematic flow sheet of the method for the kind of asphyxia type sleep-respiratory event further;
Fig. 5 to show in the embodiment of the present invention after determining that the kind of sleep-respiratory event is asphyxia type, determines the another kind of schematic flow sheet of the method for the kind of asphyxia type sleep-respiratory event further;
Fig. 6 shows the first structural representation of the certainty annuity of the kind of embodiment of the present invention sleep-respiratory event;
Fig. 7 shows the structural representation of sleep-respiratory event determination module in the embodiment of the present invention;
Fig. 8 shows the second structural representation of the certainty annuity of the kind of embodiment of the present invention sleep-respiratory event; And
Fig. 9 shows the third structural representation of the certainty annuity of the kind of embodiment of the present invention sleep-respiratory event.
Detailed description of the invention
Describe embodiments of the present invention in detail below with reference to drawings and Examples, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.It should be noted that, only otherwise form conflict, each embodiment in the present invention and each feature in each embodiment can be combined with each other, and the technical scheme formed is all within protection scope of the present invention.
Embodiment of the present invention technical problem to be solved is: the method detecting apnea or low ventilation event according to airflow signal in prior art is subject to the impact of blowby gas path, probably cause the erroneous judgement of apnea or low ventilation event or fail to judge, thus the adjustment of the mistake of the treatment pressure that positive airway pressure machine may be caused to export, affect the therapeutic effect of patient.For solving the problems of the technologies described above, embodiments provide a kind of defining method of kind of sleep-respiratory event.
As shown in Figure 1, be the schematic flow sheet of defining method of kind of embodiment of the present invention sleep-respiratory event.The defining method of the kind of the sleep-respiratory event of the embodiment of the present invention, mainly comprises the following steps:
Step 101: the respiratory chest motion waveform and the abdominal respiration moving wave shape that obtain patient.
Particularly, the respiratory chest motion waveform of Real-time Obtaining patient and abdominal respiration moving wave shape.Gather respiratory chest motion waveform and the abdominal respiration moving wave shape of a patient every the sampling period of presetting, the sampling period is such as 1 second.In the present invention one preferred embodiment, utilize the respiratory chest motion of the chest respiration monitoring device monitoring patient being provided with inductance plethysmogram pickup, utilize the abdominal respiration motion of the abdominal respiration monitoring device monitoring patient being provided with inductance plethysmogram pickup.Chest respiration monitoring device and abdominal respiration monitoring device both can be connected positive airway pressure machine by data cable, also positive airway pressure machine can be connected, in real time the respiratory chest motion waveform monitored and abdominal respiration moving wave shape are sent to positive airway pressure machine by wireless data transmission modes such as infrared, bluetooths.
When using chest respiration monitoring device, chest respiration monitoring device is fixed on the chest of patient, during patient respiratory, can move with the enlargement and contraction of chest, the respiratory movement of patient chest is traced in the change of the inductance value that chest respiration monitoring device is detected by its inner inductance plethysmogram pickup arranged, here using the respiratory chest motion waveform of the change waveform of this inductance value as patient.Similarly, when using abdominal respiration monitoring device, abdominal respiration monitoring device is fixed on patient's abdominal part, during patient respiratory, can move with the enlargement and contraction of abdominal part, the respiratory movement of patient's abdominal part is traced in the change of the inductance value that abdominal respiration monitoring device is detected by its inner inductance plethysmogram pickup arranged, here using the abdominal respiration moving wave shape of the change waveform of this inductance value as patient.
Further, other impedance plethysmogram pickuies, piezoelectric transducer or PVDF sensor also can be adopted to replace above-mentioned inductance plethysmogram pickup, monitor respiratory chest motion and the abdominal respiration motion of patient.
In specific implementation process, because chest respiration monitoring device and abdominal respiration monitoring device exist deviation, and the chest of different patient and abdominal respiration motion amplitude there are differences, be therefore necessary in this step to calibrate respectively the respiratory chest motion waveform of patient obtained and abdominal respiration moving wave shape.Particularly, the calibrating method (calibration steps) that those skilled in the art usually adopt can be applied calibrate the respiratory chest motion waveform of patient and abdominal respiration moving wave shape.
Step 102: the abdominal respiration moving wave shape after the respiratory chest motion waveform after calibration and calibration is superposed, obtains overlaid waveforms.
Step 103: when sleep-respiratory event occurs patient, according to the kind of overlaid waveforms determination sleep-respiratory event.
Particularly, when patient is in different breathing states, abdominal respiration moving wave shape after respiratory chest motion waveform after calibration or calibration there are differences, thus the overlaid waveforms of respiratory chest motion waveform corresponding to different breathing states and abdominal respiration moving wave shape also there are differences.With reference to Fig. 2 a to Fig. 2 d, sequentially show the schematic diagram of the overlaid waveforms of respiratory chest motion waveform, abdominal respiration moving wave shape and these the two kinds of respiratory movement waveforms when patient is in eupnea state, maincenter type breathing from suspending state, obstructive type breathing from suspending state and low aeration status.
As shown in Figure 2 a, the overlaid waveforms c1 of respiratory chest motion waveform a1, abdominal respiration moving wave shape b1 and two addition of waveforms when patient's eupnea is shown.As can be seen from Fig. 2 a, when patient's eupnea, the chest of patient and abdominal part enlargement and contraction simultaneously, respiratory chest motion waveform a1 and abdominal respiration moving wave shape b1 in the same way, the amplitude of the overlaid waveforms c1 be therefore formed by stacking by respiratory chest motion waveform a1 and abdominal respiration moving wave shape b1 increases, theoretically, the amplitude that the amplitude of overlaid waveforms c1 equals respiratory chest motion waveform a1 adds the amplitude of abdominal respiration moving wave shape b1.
As shown in Figure 2 b, the overlaid waveforms c2 of respiratory chest motion waveform a2, abdominal respiration moving wave shape b2 and two addition of waveforms when patient's center of origin type apnea is shown.Here, it may be noted that apnea is as the typical sleep-respiratory event of one, also referred to as asphyxia type sleep-respiratory event.As can be seen from Fig. 2 b, when patient's center of origin type apnea, the effort of patient's apnea, respiratory chest motion and abdominal respiration motion all stop, respiratory chest motion waveform a2 and abdominal respiration moving wave shape b2 is all the horizontal line of 0 close to amplitude, therefore the overlaid waveforms c2 be formed by stacking by respiratory chest motion waveform a2 and abdominal respiration moving wave shape b2 is also the horizontal line of 0 close to amplitude, and the amplitude of overlaid waveforms c2 is close to 0.
As shown in Figure 2 c, the overlaid waveforms c3 of respiratory chest motion waveform a3, abdominal respiration moving wave shape b3 and two addition of waveforms when obstructive type apnea occurs patient is shown.As can be seen from Fig. 2 c, when there is obstructive type apnea in patient, air-breathing is attempted in the chest expansion of patient, but due to airway obstruction, cannot suction gas, and abdominal part carries out corresponding contraction, therefore the respiratory chest motion waveform a3 of patient and abdominal respiration moving wave shape b3 is reverse, the overlaid waveforms c3 be formed by stacking by respiratory chest motion waveform a3 and abdominal respiration moving wave shape b3 is the horizontal line of 0 close to amplitude, and the amplitude of overlaid waveforms c3 is close to 0.
As shown in Figure 2 d, the overlaid waveforms c4 of respiratory chest motion waveform a4, abdominal respiration moving wave shape b4 and two addition of waveforms when low ventilation event occurs patient is shown.Here, it may be noted that low ventilation event is as the typical sleep-respiratory event of one, also referred to as low ventilation type sleep-respiratory event.As can be seen from Fig. 2 d, when low ventilation event occurs patient, the chest of patient and abdominal part enlargement and contraction simultaneously, respiratory chest motion waveform a4 and abdominal respiration moving wave shape b4 in the same way.Different from patient's eupnea, because the flow of the respiratory air flow of patient is little, the amplitude of the overlaid waveforms c1 when amplitude of the overlaid waveforms c4 be therefore formed by stacking by respiratory chest motion waveform a4 and abdominal respiration moving wave shape b4 is far smaller than eupnea.
The present inventor is found out by comparison diagram 2a, Fig. 2 b, Fig. 2 c and Fig. 2 d, on the one hand, no matter patient's center of origin type apnea or obstructive type apnea, the amplitude of the overlaid waveforms of respiratory chest motion waveform and abdominal respiration moving wave shape is all very little, is even 0.On the other hand, when low ventilation event occurs patient, the amplitude of the overlaid waveforms of respiratory chest motion waveform and abdominal respiration moving wave shape is far smaller than corresponding amplitude during patient's eupnea.Therefore, the embodiment of the present invention creatively when there is sleep-respiratory event in patient, according to the kind of the respiratory chest motion waveform of patient and the overlaid waveforms determination sleep-respiratory event of abdominal respiration moving wave shape.
In the present invention one preferred embodiment, the defining method of the kind of sleep-respiratory event also comprises determines that the method for sleep-respiratory event occurs patient.The present embodiment determines that the method that sleep-respiratory event occurs patient is: according to the overlaid waveforms amplitude threshold preset and overlaid waveforms, determine whether patient there occurs sleep-respiratory event.Here, according to overlaid waveforms amplitude threshold and overlaid waveforms determine patient whether there occurs sleep-respiratory event method will hereinafter composition graphs 3 carry out expansion explanation.
As shown in Figure 3, be the overlaid waveforms amplitude threshold and overlaid waveforms that in the embodiment of the present invention, basis is preset, determine whether patient there occurs the schematic flow sheet of the method for sleep-respiratory event.The present embodiment determines whether patient there occurs the method for sleep-respiratory event, mainly comprises the following steps:
Step 201: the amplitude calculating the overlaid waveforms of a nearest breathing cycle of patient.
Particularly, first the embodiment of the present invention utilizes the overlaid waveforms of distance current sample time recent breathing cycle, determine whether patient there occurs accurate sleep-respiratory event, then combine the overlaid waveforms of all breathing cycles in preset period of time subsequently, determine whether patient there occurs sleep-respiratory event.
When determining whether patient there occurs accurate sleep-respiratory event, the amplitude of the overlaid waveforms of the nearest breathing cycle first obtained by step 201, the maximum that the amplitude of overlaid waveforms equals overlaid waveforms deducts the difference of minima.Then whether patient there occurs accurate sleep-respiratory event to utilize this amplitude to determine.
Step 202: according to described amplitude and overlaid waveforms amplitude threshold, judges whether patient there occurs accurate sleep-respiratory event.
Particularly, according to described amplitude and overlaid waveforms amplitude threshold, judge that the method whether patient there occurs accurate sleep-respiratory event is: the magnitude relationship of more described amplitude and overlaid waveforms amplitude threshold, when the amplitude of comparing is less than overlaid waveforms amplitude threshold, determine that patient there occurs accurate sleep-respiratory event, when the amplitude of comparing is greater than or equal to overlaid waveforms amplitude threshold, determine that accurate sleep-respiratory event does not occur patient.
Step 203: when judging that patient there occurs accurate sleep-respiratory event, judges whether accurate sleep-respiratory event maintains the scheduled time.
Step 204: when judging that accurate sleep-respiratory event maintains the scheduled time, determines that patient there occurs sleep-respiratory event.
Particularly, after utilizing the overlaid waveforms of a nearest breathing cycle to determine that patient there occurs accurate sleep-respiratory event, judge whether this accurate sleep-respiratory event maintains the scheduled time.Here, judge that the method whether this accurate sleep-respiratory event maintains the scheduled time is: the overlaid waveforms obtaining each breathing cycle in the scheduled time slot after current time successively, and for each breathing cycle in the scheduled time slot after current time, judge whether patient there occurs accurate sleep-respiratory event during this breathing cycle.If patient all there occurs accurate sleep-respiratory event during these breathing cycles, namely show that accurate sleep-respiratory event maintains the scheduled time.In the present invention one preferred embodiment, the scheduled time is preferably 10s or more than 10s.
In the present invention one preferred embodiment, the method for the kind according to overlaid waveforms determination sleep-respiratory event in step 103 is: according to the kind of preset rules determination sleep-respiratory event; Wherein, overlaid waveforms amplitude threshold is determined according to preset rules.
Particularly, the present embodiment is when determining that patient there occurs sleep-respiratory event, and according to the preset rules determining institute's foundation in overlaid waveforms amplitude threshold process, the kind distinguishing this sleep-respiratory event belongs to asphyxia type and still belongs to low ventilation type.
Overlaid waveforms amplitude threshold is determined by the overlaid waveforms in nearest a period of time.Corresponding different types of sleep-respiratory event, determines that the preset rules of foundation during overlaid waveforms amplitude threshold is different.That is, corresponding different types of sleep-respiratory event, the determination mode of overlaid waveforms amplitude threshold is different.Typically, embodiments of the invention mainly according to the meansigma methods of the amplitude of the overlaid waveforms of each breathing cycle in the nearest preset period of time of current sample time, determine overlaid waveforms amplitude threshold.
Especially, corresponding asphyxia type sleep-respiratory event, the defining method (namely when kind is asphyxia type, determining the preset rules of overlaid waveforms amplitude threshold) of overlaid waveforms amplitude threshold is: the overlaid waveforms first extracting each breathing cycle in the nearest preset period of time of distance current sample time.Then, the amplitude of overlaid waveforms corresponding to each breathing cycle is calculated.Finally ask for the first setting percentage ratio of the meansigma methods of the amplitude of overlaid waveforms corresponding to above-mentioned all breathing cycles, and using the result asked for as the overlaid waveforms amplitude threshold corresponding to asphyxia type sleep-respiratory event.Especially, preset period of time is preferably 2 ~ 10 minutes.First setting percentage ratio is preferably 5 ~ 15%.In specific implementation process, the value needs of preset period of time and the first setting percentage ratio are demarcated further according to the experimental data of reality or test result.Such as, if the recognition accuracy that experiment or test discovery first set asphyxia type sleep-respiratory event when percentage ratio chooses 10% is the highest, then this first setting percentage ratio is preferably 10%.In like manner, if the recognition accuracy of asphyxia type sleep-respiratory event is the highest when experiment or test find that preset period of time chooses 5 minutes, then this preset period of time is preferably 5 minutes.
Similarly, corresponding low ventilation type sleep-respiratory event, the defining method (namely when kind is low ventilation type, determining the preset rules of overlaid waveforms amplitude threshold) of overlaid waveforms amplitude threshold is: the overlaid waveforms first extracting each breathing cycle in the nearest preset period of time of distance current sample time.Then, the amplitude of overlaid waveforms corresponding to each breathing cycle is calculated.Finally ask for the second setting percentage ratio of the meansigma methods of the amplitude of overlaid waveforms corresponding to above-mentioned all breathing cycles, and using the result asked for as the overlaid waveforms amplitude threshold corresponding to low ventilation type sleep-respiratory event.Especially, preset period of time is preferably 2 ~ 10 minutes.Second setting percentage ratio is preferably 30 ~ 50%.In specific implementation process, the value needs of preset period of time and the second setting percentage ratio are demarcated further according to the experimental data of reality or test result.Such as, if to set the recognition accuracy of low ventilation type sleep-respiratory event when percentage ratio chooses 50% the highest for experiment or test discovery second, then this second setting percentage ratio is preferably 50%.In like manner, if the recognition accuracy of low ventilation type sleep-respiratory event is the highest when experiment or test find that preset period of time chooses 5 minutes, then this preset period of time is preferably 5 minutes.
In the present embodiment, the overlaid waveforms of each breathing cycle in patient's nearest a period of time is utilized to determine the overlaid waveforms amplitude threshold as accurate sleep-respiratory event criterion, instead of using the fixed value of demarcating in advance as overlaid waveforms amplitude threshold, can judge whether patient there occurs sleep-respiratory event more exactly, thus the kind of sleep-respiratory event can be determined more exactly.
In the present invention one preferred embodiment, after determining that the kind of sleep-respiratory event is asphyxia type, namely after determining that sleep-respiratory event is apnea, determine the kind of asphyxia type sleep-respiratory event further, particularly, determine that asphyxia type sleep-respiratory event belongs to maincenter type or belongs to obstructive type further.
Fig. 4 to show in the embodiment of the present invention after determining that the kind of sleep-respiratory event is asphyxia type, determines a kind of schematic flow sheet of the method for the kind of asphyxia type sleep-respiratory event further.The method carries out determining for foundation with the respiratory chest motion waveform of patient, specifically comprises the following steps:
Step 301: calculate the amplitude that the respiratory chest motion waveform during asphyxia type sleep-respiratory event occurs patient, obtain thoracic breathing amplitude.
Particularly, when the kind determining sleep-respiratory event is asphyxia type, the timer for the persistent period of record apnea type sleep-respiratory event starts timing, until when determining asphyxia type sleep-respiratory event terminations.Period during this timer is defined as during asphyxia type sleep-respiratory event occurs patient.
In this step, first there is the respiratory chest motion waveform during asphyxia type sleep-respiratory event in extraction patient, and the maximum calculating this respiratory chest motion waveform deducts the difference of minima, using the amplitude of this difference as respiratory chest motion waveform during asphyxia type sleep-respiratory event occurs patient, for convenience of describing, this amplitude is called thoracic breathing amplitude.
Step 302: according to thoracic breathing amplitude threshold value and thoracic breathing amplitude, determines the kind of asphyxia type sleep-respiratory event; Wherein, thoracic breathing amplitude threshold value is determined according to the respiratory chest motion waveform of patient in nearest scheduled time slot.
The present embodiment, by analyzing the respiratory chest motion waveform of patient in a period of time, determines thoracic breathing amplitude threshold value.Particularly, the respiratory chest motion waveform of all breathing cycles in the nearest preset period of time of distance current sample time is first extracted.Then the amplitude of respiratory chest motion waveform corresponding to each breathing cycle is calculated.Finally ask for the setting percentage ratio of the meansigma methods of the amplitude of respiratory chest motion waveform corresponding to above-mentioned all breathing cycles, and using the result asked for as thoracic breathing amplitude threshold value.Especially, preset period of time is preferably 2 ~ 10 minutes; Setting percentage ratio is preferably 5 ~ 15%.In specific implementation process, the value needs of preset period of time and setting percentage ratio are demarcated further according to the experimental data of reality or test result.Such as, if the kind of asphyxia type sleep-respiratory event is determined the most accurate when experiment or test find that setting percentage ratio chooses 10%, then this setting percentage ratio is preferably 10%.In like manner, if the kind of asphyxia type sleep-respiratory event is determined the most accurate when experiment or test find that preset period of time chooses 5 minutes, then this preset period of time is preferably 5 minutes.
It is to be noted, the thoracic breathing amplitude threshold value utilizing aforesaid way to obtain is not an invariable threshold value, but the parameter constantly changed along with the respiratory movement situation of patient, in a particular embodiment, this thoracic breathing amplitude threshold value only allows to adjust, to avoid by the too small appearance accurately can not determining the phenomenon of the kind of asphyxia type sleep-respiratory event caused of the thoracic breathing amplitude threshold value determined in the adjusting range preset.
In the present embodiment, according to thoracic breathing amplitude threshold value and thoracic breathing amplitude, determine that the method for the kind of asphyxia type sleep-respiratory event is: the magnitude relationship comparing thoracic breathing amplitude and thoracic breathing amplitude threshold value, compare thoracic breathing amplitude when being less than thoracic breathing amplitude threshold value, determine that the kind of asphyxia type sleep-respiratory event is maincenter type; Compare thoracic breathing amplitude when being greater than or equal to thoracic breathing amplitude threshold value, determine that the kind of asphyxia type sleep-respiratory event is obstructive type.
Particularly, obstructive type apnea shows as during asphyxia type sleep-respiratory event occurs patient, the respiratory chest motion still sustainable existence of patient.Maincenter type apnea shows as during asphyxia type sleep-respiratory event occurs patient, and the respiratory chest motion of patient stops substantially.Therefore the present embodiment utilizes patient that the type of the respiratory chest motion waveform separation apnea during asphyxia type sleep-respiratory event occurs.
When the thoracic breathing amplitude calculated when utilizing step 301 is less than thoracic breathing amplitude threshold value, determine that patient there occurs maincenter type apnea.Otherwise, when the thoracic breathing amplitude calculated is greater than or equal to thoracic breathing amplitude threshold value, determine that patient there occurs obstructive type apnea when utilizing step 301.
Fig. 5 to show in the embodiment of the present invention after determining that the kind of sleep-respiratory event is asphyxia type, determines the another kind of schematic flow sheet of the method for the kind of asphyxia type sleep-respiratory event further.The method carries out determining for foundation with the abdominal respiration moving wave shape of patient, specifically comprises the following steps:
Step 401: calculate the amplitude that the abdominal respiration moving wave shape during asphyxia type sleep-respiratory event occurs patient, obtain abdominal breathing amplitude.
Particularly, when the kind determining sleep-respiratory event is asphyxia type, the timer for the persistent period of record apnea type sleep-respiratory event starts timing, until when determining asphyxia type sleep-respiratory event terminations.Period during this timer is defined as during asphyxia type sleep-respiratory event occurs patient.
In this step, first there is the abdominal respiration moving wave shape during asphyxia type sleep-respiratory event in extraction patient, and the maximum calculating this abdominal respiration moving wave shape deducts the difference of minima, using the amplitude of this difference as abdominal respiration moving wave shape during asphyxia type sleep-respiratory event occurs patient, for convenience of describing, this amplitude is called abdominal breathing amplitude.
Step 402: according to abdominal breathing amplitude threshold value and abdominal breathing amplitude, determines the kind of asphyxia type sleep-respiratory event; Wherein, abdominal breathing amplitude threshold value is determined according to the abdominal respiration moving wave shape of patient in nearest scheduled time slot.
The present embodiment, by analyzing the abdominal respiration moving wave shape of patient in a period of time, determines abdominal breathing amplitude threshold value.Particularly, the abdominal respiration moving wave shape of all breathing cycles in the nearest preset period of time of distance current sample time is first extracted.Then the amplitude of abdominal respiration moving wave shape corresponding to each breathing cycle is calculated.Finally ask for the setting percentage ratio of the meansigma methods of the amplitude of abdominal respiration moving wave shape corresponding to above-mentioned all breathing cycles, and using the result asked for as abdominal breathing amplitude threshold value.Especially, preset period of time is preferably 2 ~ 10 minutes; Setting percentage ratio is preferably 5 ~ 15%.In specific implementation process, the value needs of preset period of time and setting percentage ratio are demarcated further according to the experimental data of reality or test result.Such as, if the kind of asphyxia type sleep-respiratory event is determined the most accurate when experiment or test find that setting percentage ratio chooses 10%, then this setting percentage ratio is preferably 10%.In like manner, if the kind of asphyxia type sleep-respiratory event is determined the most accurate when experiment or test find that preset period of time chooses 5 minutes, then this preset period of time is preferably 5 minutes.
It is to be noted, the abdominal breathing amplitude threshold value utilizing aforesaid way to obtain is not an invariable threshold value, but the parameter constantly changed along with the respiratory movement situation of patient, in a particular embodiment, this abdominal breathing amplitude threshold value only allows to adjust, to avoid by the too small appearance accurately can not determining the phenomenon of the kind of asphyxia type sleep-respiratory event caused of the abdominal breathing amplitude threshold value determined in the adjusting range preset.
In the present embodiment, according to abdominal breathing amplitude threshold value and abdominal breathing amplitude, determine that the method for the kind of asphyxia type sleep-respiratory event is: the magnitude relationship comparing abdominal breathing amplitude and abdominal breathing amplitude threshold value, compare abdominal breathing amplitude when being less than abdominal breathing amplitude threshold value, determine that the kind of asphyxia type sleep-respiratory event is maincenter type; Compare abdominal breathing amplitude when being greater than or equal to abdominal breathing amplitude threshold value, determine that the kind of asphyxia type sleep-respiratory event is obstructive type.
Particularly, obstructive type apnea shows as during asphyxia type sleep-respiratory event occurs patient, and the abdominal respiration of patient is moved still sustainable existence.Maincenter type apnea shows as during asphyxia type sleep-respiratory event occurs patient, and the abdominal respiration motion of patient is basic to be stopped.Therefore the present embodiment utilizes patient's abdominal respiration moving wave shape occurred during asphyxia type sleep-respiratory event to distinguish the type of apnea.
When the abdominal breathing amplitude calculated when utilizing step 401 is less than abdominal breathing amplitude threshold value, determine that patient there occurs maincenter type apnea.Otherwise, when the abdominal breathing amplitude calculated is greater than or equal to abdominal breathing amplitude threshold value, determine that patient there occurs obstructive type apnea when utilizing step 401.
After the kind determining asphyxia type sleep-respiratory event is maincenter type, can the positive airway pressure machine (namely treat pressure can in the range of regulation of setting the positive airway pressure machine of adjustment) of automatic Regulation automatically reduce its treatment pressure exported or maintain current treatment pressure constant.After the kind determining asphyxia type sleep-respiratory event is obstructive type or when the kind determining sleep-respiratory event is low ventilation type, the positive airway pressure machine of automatic Regulation can increase its treatment pressure exported automatic continuously, preferably increase 0.5cmH2O, until the breathing state of patient recovers normal at every turn.If patient continues eupnea a period of time (being preferably 3 minutes), if determine there is not obstructive type apnea or low ventilation event in patient, then in order to improve the compliance of patient, to slowly reduce treatment pressure, preferably reduce 0.5cmH2O, until again there is obstructive type apnea or low ventilation event.
Correspondingly, the embodiment of the present invention also provides a kind of certainty annuity of kind of sleep-respiratory event.
As shown in Figure 6, be the first structural representation of certainty annuity of kind of embodiment of the present invention sleep-respiratory event.The certainty annuity of the kind of the sleep-respiratory event of the present embodiment comprises the respiratory movement waveform acquisition module 501, addition of waveforms module 502 and the first kind determination module 503 that connect in turn.
Particularly, respiratory movement waveform acquisition module 501, is set to the respiratory chest motion waveform and the abdominal respiration moving wave shape that obtain patient.Respiratory waveform acquisition module 501 comprises the abdominal respiration monitoring device of the chest respiratory waveform acquiring unit for the respiratory chest motion waveform of Real-time Obtaining patient and the abdominal exercise waveform for Real-time Obtaining patient.In the present invention one preferred embodiment, chest respiration monitoring device and abdominal respiration monitoring device all have inductance plethysmogram pickup.Chest respiration monitoring device and abdominal respiration monitoring device both can be connected positive airway pressure machine by data cable, also positive airway pressure machine can be connected, in real time the respiratory chest motion waveform monitored and abdominal respiration moving wave shape are sent to positive airway pressure machine by wireless data transmission modes such as infrared, bluetooths.
When using chest respiration monitoring device, chest respiration monitoring device is fixed on the chest of patient, during patient respiratory, can move with the enlargement and contraction of chest, the respiratory movement of patient chest is traced in the change of the inductance value that chest respiration monitoring device is detected by its inner inductance plethysmogram pickup arranged, here using the respiratory chest motion waveform of the change waveform of this inductance value as patient.Similarly, when using abdominal respiration monitoring device, abdominal respiration monitoring device is fixed on patient's abdominal part, during patient respiratory, can move with the enlargement and contraction of abdominal part, the respiratory movement of patient's abdominal part is traced in the change of the inductance value that abdominal respiration monitoring device is detected by its inner inductance plethysmogram pickup arranged, here using the abdominal respiration moving wave shape of the change waveform of this inductance value as patient.
Further, other impedance plethysmogram pickuies, piezoelectric transducer or PVDF sensor also can be adopted to replace above-mentioned inductance plethysmogram pickup, monitor respiratory chest motion and the abdominal respiration motion of patient.
Addition of waveforms module 502, is set to superpose respiratory chest motion waveform and abdominal respiration moving wave shape, obtains overlaid waveforms.
First kind determination module 503, is set to when sleep-respiratory event occurs patient, according to the kind of overlaid waveforms determination sleep-respiratory event.
Particularly, with reference to Fig. 2 a to Fig. 2 d, when patient is in different breathing states, the respiratory chest motion waveform obtained or abdominal respiration moving wave shape there are differences, thus the overlaid waveforms of respiratory chest motion waveform corresponding to different breathing states and abdominal respiration moving wave shape also there are differences.Therefore, in the present embodiment, first by addition of waveforms module 502, respiratory chest motion waveform and abdominal respiration moving wave shape are superposed, obtain overlaid waveforms.Then the first kind determination module 503 is when there is sleep-respiratory event in patient, determines the kind of sleep-respiratory event according to the overlaid waveforms of addition of waveforms module 502 output.
In the present invention one preferred embodiment, the certainty annuity of the kind of sleep-respiratory event also comprises the sleep-respiratory event determination module be electrically connected with the first kind determination module.Sleep-respiratory event determination module is set to, according to default overlaid waveforms amplitude threshold and overlaid waveforms, determine whether patient there occurs sleep-respiratory event.The concrete structure of sleep-respiratory event determination module will be set forth by composition graphs 7 hereinafter in detail.
As shown in Figure 7, be the structural representation of sleep-respiratory event determination module in the embodiment of the present invention.The sleep-respiratory event determination module of the embodiment of the present invention comprises magnitude computation unit 601, first judging unit 602, second judging unit 603 and determining unit 604 that connect in turn.
Particularly, magnitude computation unit 601, is set to the amplitude of the overlaid waveforms of the nearest breathing cycle calculating patient.First magnitude computation unit 601 extracts the overlaid waveforms of a nearest breathing cycle from complete overlaid waveforms, then calculates the amplitude of the overlaid waveforms of a nearest breathing cycle, and the maximum that amplitude equals this overlaid waveforms deducts the difference of minima.
First judging unit 602, is set to according to described amplitude and overlaid waveforms amplitude threshold, judges whether patient accurate sleep-respiratory event occurs.
Particularly, first judging unit 602 is specifically set to: the magnitude relationship comparing amplitude and overlaid waveforms amplitude threshold, when the amplitude of comparing is less than overlaid waveforms amplitude threshold, determine that patient there occurs accurate sleep-respiratory event, when the amplitude of comparing is greater than or equal to overlaid waveforms amplitude threshold, determine that accurate sleep-respiratory event does not occur patient
Second judging unit 603, is set to, when the first judging unit 602 judges that patient there occurs accurate sleep-respiratory event, judge whether accurate sleep-respiratory event maintains the scheduled time.
Particularly, second judging unit 603 is specifically set to: the overlaid waveforms obtaining each breathing cycle in the scheduled time slot after current time successively, and for each breathing cycle in the scheduled time slot after current time, judge whether patient there occurs accurate sleep-respiratory event during this breathing cycle.If patient all there occurs accurate sleep-respiratory event during these breathing cycles, namely show that accurate sleep-respiratory event maintains the scheduled time.In the present invention one preferred embodiment, the scheduled time is preferably 10s or more than 10s.
Determining unit 604, is set to, when the second judging unit 603 judges that accurate sleep-respiratory event maintains the scheduled time, determine that patient there occurs sleep-respiratory event.
In the present invention one preferred embodiment, the first kind determination module 503 is specifically set to: when sleep-respiratory event occurs patient, according to the kind of preset rules determination sleep-respiratory event; Wherein, overlaid waveforms amplitude threshold is determined according to stating preset rules.
Particularly, overlaid waveforms amplitude threshold is determined by the overlaid waveforms in nearest a period of time.Corresponding different types of sleep-respiratory event, determines that the preset rules of foundation during overlaid waveforms amplitude threshold is different.That is, corresponding different types of sleep-respiratory event, the determination mode of overlaid waveforms amplitude threshold is different.Typically, embodiments of the invention mainly according to the meansigma methods of the amplitude of the overlaid waveforms of each breathing cycle in the nearest preset period of time of current sample time, determine overlaid waveforms amplitude threshold.
Especially, corresponding asphyxia type sleep-respiratory event, the defining method (namely when kind is asphyxia type, determining the preset rules of overlaid waveforms amplitude threshold) of overlaid waveforms amplitude threshold is: the overlaid waveforms first extracting each breathing cycle in the nearest preset period of time of distance current sample time.Then, the amplitude of overlaid waveforms corresponding to each breathing cycle is calculated.Finally ask for the first setting percentage ratio of the meansigma methods of the amplitude of overlaid waveforms corresponding to above-mentioned all breathing cycles, and using the result asked for as the overlaid waveforms amplitude threshold corresponding to asphyxia type sleep-respiratory event.Especially, preset period of time is preferably 2 ~ 10 minutes.First setting percentage ratio is preferably 5 ~ 15%.In specific implementation process, the value needs of preset period of time and the first setting percentage ratio are demarcated further according to the experimental data of reality or test result.Such as, if the recognition accuracy that experiment or test discovery first set asphyxia type sleep-respiratory event when percentage ratio chooses 10% is the highest, then this first setting percentage ratio is preferably 10%.In like manner, if the recognition accuracy of asphyxia type sleep-respiratory event is the highest when experiment or test find that preset period of time chooses 5 minutes, then this preset period of time is preferably 5 minutes.
Similarly, corresponding low ventilation type sleep-respiratory event, the defining method (namely when kind is low ventilation type, determining the preset rules of overlaid waveforms amplitude threshold) of overlaid waveforms amplitude threshold is: the overlaid waveforms first extracting each breathing cycle in the nearest preset period of time of distance current sample time.Then, the amplitude of overlaid waveforms corresponding to each breathing cycle is calculated.Finally ask for the second setting percentage ratio of the meansigma methods of the amplitude of overlaid waveforms corresponding to above-mentioned all breathing cycles, and using the result asked for as the overlaid waveforms amplitude threshold corresponding to low ventilation type sleep-respiratory event.Especially, preset period of time is preferably 2 ~ 10 minutes.Second setting percentage ratio is preferably 30 ~ 50%.In specific implementation process, the value needs of preset period of time and the second setting percentage ratio are demarcated further according to the experimental data of reality or test result.Such as, if to set the recognition accuracy of low ventilation type sleep-respiratory event when percentage ratio chooses 50% the highest for experiment or test discovery second, then this second setting percentage ratio is preferably 50%.In like manner, if the recognition accuracy of low ventilation type sleep-respiratory event is the highest when experiment or test find that preset period of time chooses 5 minutes, then this preset period of time is preferably 5 minutes.
In the present embodiment, first kind determination module 503 utilizes the overlaid waveforms of each breathing cycle in patient's nearest a period of time to determine the overlaid waveforms amplitude threshold as accurate sleep-respiratory event criterion, instead of using the fixed value of demarcating in advance as overlaid waveforms amplitude threshold, can judge whether patient there occurs sleep-respiratory event more exactly, thus the kind of sleep-respiratory event can be determined more exactly.
As shown in Figure 8, be the second structural representation of certainty annuity of kind of embodiment of the present invention sleep-respiratory event.The certainty annuity of the kind of the present embodiment sleep-respiratory event, except comprising the respiratory movement waveform acquisition module 501, addition of waveforms module 502 and the first kind determination module 503 that connect in turn, also comprises thoracic breathing amplitude determination module 701 and the second kind determination module 702.Wherein, the first kind determination module 503 is connected with the second kind determination module 702 by thoracic breathing amplitude determination module 701.After the present embodiment is intended to determine that the kind of sleep-respiratory event is asphyxia type, namely after determining that sleep-respiratory event is apnea, utilize the kind of the respiratory chest motion waveform determination asphyxia type sleep-respiratory event of patient further, particularly, determine that asphyxia type sleep-respiratory event belongs to maincenter type or belongs to obstructive type further.
Particularly, thoracic breathing amplitude determination module 701, is set to calculate the amplitude that the respiratory chest motion waveform during asphyxia type sleep-respiratory event occurs patient, obtains thoracic breathing amplitude.
Particularly, first thoracic breathing amplitude determination module 701 extracts the respiratory chest motion waveform that patient occurs during asphyxia type sleep-respiratory event, and the maximum calculating this respiratory chest motion waveform deducts the difference of minima, using the amplitude of this difference as respiratory chest motion waveform during asphyxia type sleep-respiratory event occurs patient, for convenience of describing, this amplitude is called thoracic breathing amplitude.
Second kind determination module 702, is set to according to thoracic breathing amplitude threshold value and thoracic breathing amplitude, determines the kind of asphyxia type sleep-respiratory event; Wherein, thoracic breathing amplitude threshold value is determined according to the respiratory chest motion waveform of patient in nearest scheduled time slot.
Particularly, second kind determination module 702 is specifically set to: the magnitude relationship comparing thoracic breathing amplitude and thoracic breathing amplitude threshold value, compare thoracic breathing amplitude when being less than thoracic breathing amplitude threshold value, determine that the kind of asphyxia type sleep-respiratory event is maincenter type; Compare thoracic breathing amplitude when being greater than or equal to thoracic breathing amplitude threshold value, determine that the kind of asphyxia type sleep-respiratory event is obstructive type.
As shown in Figure 9, be the third structural representation of certainty annuity of kind of embodiment of the present invention sleep-respiratory event.The certainty annuity of the kind of the present embodiment sleep-respiratory event, except comprising the respiratory movement waveform acquisition module 501, addition of waveforms module 502 and the first kind determination module 503 that connect in turn, also comprises abdominal breathing amplitude determination module 801 and the third class determination module 802.Wherein, the first kind determination module 503 is connected with the third class determination module 802 by abdominal breathing amplitude determination module 801.After the present embodiment is intended to determine that the kind of sleep-respiratory event is asphyxia type, namely after determining that sleep-respiratory event is apnea, utilize the kind of the abdominal respiration moving wave shape determination asphyxia type sleep-respiratory event of patient further, particularly, determine that asphyxia type sleep-respiratory event belongs to maincenter type or belongs to obstructive type further.
Particularly, abdominal breathing amplitude determination module 801, is set to calculate the amplitude that the abdominal respiration moving wave shape during asphyxia type sleep-respiratory event occurs patient, obtains abdominal breathing amplitude.
Particularly, first abdominal breathing amplitude determination module 801 extracts the abdominal respiration moving wave shape that patient occurs during asphyxia type sleep-respiratory event, and the maximum calculating this abdominal respiration moving wave shape deducts the difference of minima, using the amplitude of this difference as abdominal respiration moving wave shape during asphyxia type sleep-respiratory event occurs patient, for convenience of describing, this amplitude is called abdominal breathing amplitude.
The third class determination module 802, is set to according to abdominal breathing amplitude threshold value and abdominal breathing amplitude, determines the kind of asphyxia type sleep-respiratory event; Wherein, abdominal breathing amplitude threshold value is determined according to the abdominal respiration moving wave shape of patient in nearest scheduled time slot.
Particularly, the third class determination module 802 is specifically set to: the magnitude relationship comparing abdominal breathing amplitude and abdominal breathing amplitude threshold value, compare abdominal breathing amplitude when being less than abdominal breathing amplitude threshold value, determine that the kind of asphyxia type sleep-respiratory event is maincenter type; Compare abdominal breathing amplitude when being greater than or equal to abdominal breathing amplitude threshold value, determine that the kind of asphyxia type sleep-respiratory event is obstructive type.
The concrete processing procedure of above-mentioned each unit can refer to the description in the method for the embodiment of the present invention above.
The method detecting apnea or low ventilation event according to airflow signal in prior art is subject to the impact of blowby gas path, probably cause the erroneous judgement of apnea or low ventilation event or fail to judge, thus the adjustment of the mistake of the treatment pressure that positive airway pressure machine may be caused to export, affect the therapeutic effect of patient.Embodiments of the invention are relative to prior art, using the respiratory chest motion waveform of patient and the overlaid waveforms of abdominal respiration moving wave shape as the confirmed standard of kind determining sleep-respiratory event, because this confirmed standard is not by the impact of blowby gas path, therefore, it is possible to accurately and reliably determine the kind of sleep-respiratory event, and then be that the treatment pressure adjusting positive airway pressure machine provides accurate foundation, substantially increase the therapeutic effect of patient and the compliance for the treatment of, significantly improve the experience of patient.In addition, obviously more stable than reflection airflow signal owing to reflecting the respirometric signal of patient, therefore the capacity of resisting disturbance of the embodiment of the present invention is strong.
Those skilled in the art should be understood that, above-mentioned of the present invention each module or each step can realize with general accountant, they can concentrate on single accountant, or be distributed on network that multiple accountant forms, alternatively, they can realize with the executable program code of accountant, thus, they can be stored and be performed by accountant in the storage device, or they are made into each integrated circuit modules respectively, or the multiple module in them or step are made into single integrated circuit module to realize.Like this, the present invention is not restricted to any specific hardware and software combination.
Although embodiment disclosed in this invention is as above, the embodiment that described content just adopts for the ease of understanding the present invention, and be not used to limit the present invention.Technical staff in any the technical field of the invention; under the prerequisite not departing from spirit and scope disclosed in this invention; any amendment and change can be done what implement in form and in details; but protection scope of the present invention, the scope that still must define with appending claims is as the criterion.

Claims (10)

1. a defining method for the kind of sleep-respiratory event, is characterized in that, comprising:
Obtain respiratory chest motion waveform and the abdominal respiration moving wave shape of patient;
Described respiratory chest motion waveform and described abdominal respiration moving wave shape are superposed, obtains overlaid waveforms;
When sleep-respiratory event occurs described patient, determine the kind of described sleep-respiratory event according to described overlaid waveforms.
2. method according to claim 1, is characterized in that, the method comprises:
According to the overlaid waveforms amplitude threshold preset and described overlaid waveforms, determine whether described patient there occurs sleep-respiratory event.
3. method according to claim 2, is characterized in that, according to the overlaid waveforms amplitude threshold preset and described overlaid waveforms, determines whether described patient there occurs sleep-respiratory event, comprising:
Calculate the amplitude of the overlaid waveforms of a nearest breathing cycle of described patient;
According to described amplitude and described overlaid waveforms amplitude threshold, judge whether described patient there occurs accurate sleep-respiratory event;
When judging that described patient there occurs accurate sleep-respiratory event, judge whether described accurate sleep-respiratory event maintains the scheduled time;
When judging that described accurate sleep-respiratory event maintains the scheduled time, determine that described patient there occurs sleep-respiratory event.
4. method according to claim 2, is characterized in that, determines the kind of described sleep-respiratory event, comprising according to described overlaid waveforms:
The kind of described sleep-respiratory event is determined according to preset rules;
Wherein, described overlaid waveforms amplitude threshold is determined according to described preset rules.
5. method according to any one of claim 1 to 4, is characterized in that, when the kind determining described sleep-respiratory event is asphyxia type, described method also comprises:
Calculate the amplitude that the respiratory chest motion waveform during asphyxia type sleep-respiratory event occurs described patient, obtain thoracic breathing amplitude;
According to thoracic breathing amplitude threshold value and described thoracic breathing amplitude, determine the kind of asphyxia type sleep-respiratory event; Wherein, described thoracic breathing amplitude threshold value is determined according to the respiratory chest motion waveform of patient in nearest scheduled time slot; Or
Calculate the amplitude that the abdominal respiration moving wave shape during asphyxia type sleep-respiratory event occurs described patient, obtain abdominal breathing amplitude;
According to abdominal breathing amplitude threshold value and described abdominal breathing amplitude, determine the kind of asphyxia type sleep-respiratory event; Wherein, described abdominal breathing amplitude threshold value is determined according to the abdominal respiration moving wave shape of patient in nearest scheduled time slot.
6. a certainty annuity for the kind of sleep-respiratory event, is characterized in that, comprising:
Respiratory movement waveform acquisition module, is set to the respiratory chest motion waveform and the abdominal respiration moving wave shape that obtain patient;
Addition of waveforms module, is set to superpose described respiratory chest motion waveform and described abdominal respiration moving wave shape, obtains overlaid waveforms;
First kind determination module, is set to, when sleep-respiratory event occurs described patient, determine the kind of described sleep-respiratory event according to described overlaid waveforms.
7. system according to claim 6, is characterized in that, described system also comprises:
Sleep-respiratory event determination module, being set to the overlaid waveforms amplitude threshold according to presetting and described overlaid waveforms, determining whether described patient there occurs sleep-respiratory event.
8. system according to claim 7, is characterized in that, described sleep-respiratory event determination module comprises:
Magnitude computation unit, is set to the amplitude of the overlaid waveforms of the nearest breathing cycle calculating described patient;
First judging unit, is set to, according to described amplitude and described overlaid waveforms amplitude threshold, judge whether described patient there occurs accurate sleep-respiratory event;
Second judging unit, is set to when described first judging unit judges that described patient there occurs accurate sleep-respiratory event, judges whether described accurate sleep-respiratory event maintains the scheduled time;
Determining unit, is set to, when described second judging unit judges that described accurate sleep-respiratory event maintains the scheduled time, determine that described patient there occurs sleep-respiratory event.
9. system according to claim 7, is characterized in that, described first kind determination module is specifically set to: when sleep-respiratory event occurs described patient, determines the kind of described sleep-respiratory event according to preset rules; Wherein, described overlaid waveforms amplitude threshold is determined according to described preset rules.
10. the system according to any one of claim 6 to 9, is characterized in that, described system also comprises:
Thoracic breathing amplitude determination module, is set to calculate the amplitude that the respiratory chest motion waveform during asphyxia type sleep-respiratory event occurs described patient, obtains thoracic breathing amplitude;
Second kind determination module, is set to, according to thoracic breathing amplitude threshold value and described thoracic breathing amplitude, determine the kind of asphyxia type sleep-respiratory event; Wherein, described thoracic breathing amplitude threshold value is determined according to the respiratory chest motion waveform of patient in nearest scheduled time slot; Or
Abdominal breathing amplitude determination module, is set to calculate the amplitude that the abdominal respiration moving wave shape during asphyxia type sleep-respiratory event occurs described patient, obtains abdominal breathing amplitude;
The third class determination module, is set to, according to abdominal breathing amplitude threshold value and described abdominal breathing amplitude, determine the kind of asphyxia type sleep-respiratory event; Wherein, described abdominal breathing amplitude threshold value is determined according to the abdominal respiration moving wave shape of patient in nearest scheduled time slot.
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