CN104678038B - There is the GC-MS of dual ion sources - Google Patents
There is the GC-MS of dual ion sources Download PDFInfo
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- CN104678038B CN104678038B CN201510008360.0A CN201510008360A CN104678038B CN 104678038 B CN104678038 B CN 104678038B CN 201510008360 A CN201510008360 A CN 201510008360A CN 104678038 B CN104678038 B CN 104678038B
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Abstract
The invention provides a kind of GC-MS with dual ion sources, described GC-MS includes mass spectrograph, liquid-chromatography module, gas-chromatography module；Described GC-MS farther includes: first passage, and described liquid-chromatography module is sequentially connected with atmospheric pressure ionizationion, vacuum interface, the first ion focusing lenses；Second channel, described gas-chromatography module connects vacuum ionization source；Ion deflecting lens, described ion deflecting lens have the first entrance, the second entrance and exit, described first entrance, the second entrance turn 90 degrees the most partially to described outlet, described first entrance connects described first ion focusing lenses, described second entrance connects described vacuum ionization source, and described outlet connects the second ion focusing lenses；Second ion focusing lenses, described second ion focusing lenses is arranged between described ion deflecting lens and mass spectrograph.Present invention achieves dual ion sources and be simultaneously connected with mass spectrograph, can analyze simultaneously.
Description
Technical field
The present invention relates to application of gas chromatorgraphy/mass, particularly to the GC-MS of dual ion sources.
Background technology
Triple quadrupole mass spectrometer is typically combined, when being combined with liquid chromatogram with liquid chromatogram or gas-chromatography
Use atmospheric pressure ionizationion (such as ESI) more, when being connected with gas-chromatography, general employing vacuum ionization source (as
EI).Experimentation can not use atmospheric pressure ionization source and vacuum ionization source simultaneously, need to unload after vacuum more
Colour changing matter interface could use another ionization source.
Visible, when application of gas chromatorgraphy/mass, need to change corresponding chromaticness interface, with meet atmospheric pressure ionizationion and
The use requirement of vacuum ionization source, needs vacuum unloading in Renewal process, is starting very after having changed
Dry running instrument, Renewal process takes long enough, it is impossible to realize being simultaneously connected with liquid chromatogram and gas-chromatography
Function.
Summary of the invention
In order to solve the deficiency in above-mentioned prior art, the invention provides one realize liquid chromatogram and
The GC-MS with dual ion sources of gas-chromatography sample introduction simultaneously.
It is an object of the invention to be achieved through the following technical solutions:
A kind of GC-MS with dual ion sources, described GC-MS includes mass spectrograph, liquid chromatogram
Module, gas-chromatography module；Described GC-MS farther includes:
First passage, described liquid-chromatography module be sequentially connected with atmospheric pressure ionizationion, vacuum interface, first from
Sub-condenser lens；
Second channel, described gas-chromatography module connects vacuum ionization source；
Ion deflecting lens, described ion deflecting lens have the first entrance, the second entrance and exit, described
First entrance, the second entrance turn 90 degrees the most partially to described outlet, and described first entrance connects described first ion
Condenser lens, described second entrance connects described vacuum ionization source, and it is saturating that described outlet connects the second ion focusing
Mirror；
Second ion focusing lenses, described second ion focusing lenses is arranged on described ion deflecting lens and matter
Between spectrometer.
According to above-mentioned GC-MS, it is preferable that described ion deflecting lens include:
First electrode, described first electrode has the first curved surfaces；
Second electrode, described second electrode has second curved surfaces relative with described first curved surfaces；
3rd electrode, described 3rd electrode extend into has threeth arc relative with described first curved surfaces
Surface, constitutes the passage partially turning 90 degrees；And there is fourth curved surfaces relative with described second curved surfaces,
Constitute the passage partially turning 90 degrees.
According to above-mentioned GC-MS, it is preferable that described second ion focusing lenses includes three annular electro
Pole, and taper into along the aperture of the annular electrode in ion exit direction.
Compared with prior art, the device have the advantages that into:
Atmospheric pressure ionizationion and vacuum ionic source are each attached to mass spectrograph, it is achieved that liquid chromatogram and gas-chromatography
While sample introduction, it is not necessary to according to detection object and more alias.
Accompanying drawing explanation
Referring to the drawings, the disclosure will be easier to understand.Skilled addressee readily understands that
: these accompanying drawings are used only for illustrating technical scheme, and are not intended to the present invention's
Protection domain is construed as limiting.In figure:
Fig. 1 is the structure diagram of GC-MS according to embodiments of the present invention；
Fig. 2 is the sectional view of ion deflecting lens according to embodiments of the present invention.
Detailed description of the invention
Fig. 1-2 and following description describe the optional embodiment of the present invention with teaching those skilled in the art such as
What is implemented and reproduces the present invention.In order to instruct technical solution of the present invention, simplify or eliminate some routine sides
Face.Those skilled in the art should understand that and be derived from the modification of these embodiments or replace the model in the present invention
In enclosing.Those skilled in the art should understand that following characteristics can combine to form the present invention's in every way
Multiple modification.Thus, the invention is not limited in following optional embodiment, and only by claim and it
Equivalent limit.
Embodiment:
Fig. 1 schematically illustrates the structure letter of the GC-MS with dual ion sources of the embodiment of the present invention
Figure, as it is shown in figure 1, described GC-MS includes:
Triple level Four bar mass spectrographs, liquid-chromatography module, gas-chromatography module；
First passage, described liquid-chromatography module be sequentially connected with atmospheric pressure ionizationion, vacuum interface, first from
Sub-condenser lens；Described vacuum interface includes ion transport module, accommodates the vacuum cavity of this transport module,
Described ion transport module is multistage bar or ion funnel；Described first ion focusing lenses is by three annular electrodes
Composition；
Second channel, described gas-chromatography module connects vacuum ionization source；
Fig. 2 schematically illustrates the structure diagram of the ion deflecting lens of the embodiment of the present invention, such as Fig. 2 institute
Showing, described ion deflecting lens include:
First electrode 11, described first electrode has the first curved surfaces 12；
Second electrode 21, described second electrode has the second arc table relative with described first curved surfaces 12
Face 22；
3rd electrode 31, described 3rd electrode extend into has threeth relative with described first curved surfaces 12
Curved surfaces 32, constitutes the first ion channel partially turning 90 degrees, and this passage has the first entrance 113 and outlet
14；And there is fourth curved surfaces 33 relative with described second curved surfaces 22, composition turn 90 degrees partially
Second ion channel, this passage has the second entrance 23 and outlet 14, the first ion channel and the second ion lead to
Road shares outlet；
Second ion focusing lenses, described second ion focusing lenses is arranged on described ion deflecting lens and matter
Between spectrometer, having three annular electrodes, it tapers into along the aperture in ion exit direction；
Power supply, described offer DC voltage, power for above-mentioned each electrode, ion gun, mass spectrograph.
The working method of above-mentioned GC-MS is:
Liquid chromatogram sample introduction, after atmospheric pressure ionizationion is ionized, by ion transport module, gathers afterwards
Burnt；
Ion after focusing enters deflection lens, again focuses on, finally enter triple level Four bar after partially turning 90 degrees
In mass spectrograph；
Meanwhile, gas chromatographic sample introduction, ionized in vacuum ionic source, enter ion deflecting lens afterwards,
Focus on after partially turning 90 degrees, finally enter triple level Four bar mass spectrograph.
Claims (2)
1. having a GC-MS for dual ion sources, described GC-MS includes mass spectrograph, liquid phase look
Spectrum module, gas-chromatography module；It is characterized in that: described GC-MS farther includes:
First passage, described liquid-chromatography module be sequentially connected with atmospheric pressure ionizationion, vacuum interface, first from
Sub-condenser lens；
Second channel, described gas-chromatography module connects vacuum ionization source；
Ion deflecting lens, described ion deflecting lens have the first entrance, the second entrance and exit, described
First entrance, the second entrance turn 90 degrees the most partially to described outlet, and described first entrance connects described first ion
Condenser lens, described second entrance connects described vacuum ionization source, and it is saturating that described outlet connects the second ion focusing
Mirror；
Second ion focusing lenses, described second ion focusing lenses is arranged on described ion deflecting lens and matter
Between spectrometer；
Described ion deflecting lens include:
First electrode, described first electrode has the first curved surfaces；
Second electrode, described second electrode has second curved surfaces relative with described first curved surfaces；
3rd electrode, described 3rd electrode have threeth curved surfaces relative with described first curved surfaces,
Fourth curved surfaces relative with described second curved surfaces；Described 3rd electrode stretch into described first electrode with
Between second electrode, constitute, with described first electrode, the passage partially turning 90 degrees, and constitute with described second electrode
The passage partially turning 90 degrees.
GC-MS the most according to claim 1, it is characterised in that: described second ion focusing is saturating
Mirror includes three annular electrodes, and tapers into along the aperture of the annular electrode in ion exit direction.
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| CN201510008360.0A CN104678038B (en) | 2015-01-08 | 2015-01-08 | There is the GC-MS of dual ion sources |
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| CN201510008360.0A CN104678038B (en) | 2015-01-08 | 2015-01-08 | There is the GC-MS of dual ion sources |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107359104B (en) * | 2017-06-14 | 2018-07-20 | 中国科学院地质与地球物理研究所 | A kind of magnetic substance spectralyzer couples conversion equipment with dual ion sources |
| CN107359100A (en) * | 2017-06-28 | 2017-11-17 | 武汉华星光电技术有限公司 | A kind of ion implantation apparatus and its application method |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| GB2349270B (en) * | 1999-04-15 | 2002-02-13 | Hitachi Ltd | Mass analysis apparatus and method for mass analysis |
| JP3840417B2 (en) * | 2002-02-20 | 2006-11-01 | 株式会社日立ハイテクノロジーズ | Mass spectrometer |
| CN103515183B (en) * | 2012-06-20 | 2017-06-23 | 株式会社岛津制作所 | Ion guide device and ion guides method |
| CN102800553B (en) * | 2012-09-02 | 2015-07-29 | 王利兵 | A kind of gas phase liquid chromatogram-electronics bombardment electron spray dual ion source flight time mass spectrum system |
| CN102800554B (en) * | 2012-09-02 | 2015-08-19 | 王利兵 | A kind of multimode ionization method |
| CN103311087A (en) * | 2013-05-16 | 2013-09-18 | 复旦大学 | Ion deflection transmission system |
| CN103779167A (en) * | 2013-12-31 | 2014-05-07 | 聚光科技(杭州)股份有限公司 | ICP-MS device and method thereof |
| CN203870076U (en) * | 2014-04-01 | 2014-10-08 | 聚光科技(杭州)股份有限公司 | Detection device for chromatography mass spectrometry instrument |
| CN204666582U (en) * | 2015-01-08 | 2015-09-23 | 聚光科技(杭州)股份有限公司 | There is the GC-MS of dual ion sources |
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Effective date of registration: 20160801 Address after: Hangzhou City, Zhejiang province Binjiang District 310052 shore road 760 Applicant after: Focused Photonics (Hangzhou) Inc. Applicant after: Hangzhou Pu Yu development in science and technology Co., Ltd Address before: Hangzhou City, Zhejiang province Binjiang District 310052 shore road 760 Applicant before: Focused Photonics (Hangzhou) Inc. |
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