CN104666172A - 一种美白保湿护肤品 - Google Patents
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Abstract
本发明公开了一种美白保湿护肤品，该护肤品由植物提取物、护肤基质和去离子水制备而成，所述的植物提取物为水仙花花瓣的氯仿提取部位。本发明提供的美白护肤品效果显著，可增强皮肤的锁水能力，降低皮肤黑色素含量，具有美白保湿的功效；同时，产品对皮肤无刺激性，安全可靠。
Description
技术领域
本发明属于日用化妆品技术领域，具体而言，涉及一种护肤品，尤其涉及一种以植物提取物为主要功效组分的美白保湿护肤品。
背景技术
皮肤是人体最大的器官，总重量占体重的 5％～15％，总面积为 1.5～2平方米，厚度因人或因部位而异，为0.5～4毫米。皮肤覆盖全身，与人体的其它器官密切相连，起着保护人体不受外部刺激或伤害的作用。皮肤具有两个方面的屏障作用：一方面防止体内水分，电解质和其他物质的丢失；另一方面阻止外界有害物质的侵入。保持着人体内环境的稳定，在生理上起着重要的保护功能，同时皮肤也参与人体的代谢过程。如果想拥有健康漂亮的肌肤，除了要养成健康的生活习惯，还要做好防护保养工作，尤其对于平时裸露在外的皮肤，如脸部、颈部、手、臂部等，更要悉心呵护。
研究证明，很多植物中含有大量的生物活性成分，具有抗氧化和清除体内自由基的作用，可以提高机体免疫能力并延缓衰老。当人体内原本平衡的氧化剂和抗氧化剂由于自由基的超量而失衡时，就会导致氧化应激和DNA损伤。过剩的自由基攻击DNA，引起基质突变、单键和双链断裂、DNA交链、染色体断裂和基因重排等问题。现代生物医学研究表明，植物中含有大量抗氧化剂，能清除体内过多的氧自由基。爱美之心，人皆有之。以安全性为前提，开发以纯天然植物为主要功效成分、滋养容颜为目的的化妆品是十分有意义的。
水仙花为石蒜科植物水仙的花，拉丁植物动物矿物名：Narcissus tazetta L.var. chinensis Roem.，多年生草本。鳞茎卵球形。叶基生，直立而扁平，宽线形，长20-40cm，宽8-15mm，先端钝，全缘，粉绿色。花茎中空，扁平，几与叶等长；伞房花序有花4-8朵，花轴承平伸或下垂；总苞片佛焰苞状，膜质；花芳香；花梗突出包外；花被管细，近三棱形，长约2cm，灰绿色；花被裂片6，卵圆形至阔椭圆形，先端具短尖头，扩展而外反，白色，副花冠浅杯状，淡黄色，不皱缩，短于花被；雄蕊6，着生于花被管内，花药基着；子房3室，每室有胚珠多数，花柱细长，柱头3列。蒴果室背开裂。花期春季，果期4-5月。水仙花的花瓣在春季采摘，晒干，花皱缩成小团块；展开后，花被管细，先端裂片6，卵圆形，淡黄色，其内可见黄棕色环状副花冠，有的花被呈重瓣状。雄蕊6，雌蕊花柱细长，柱头3裂；气芳香，味微苦。目前，尚无文献报道水仙花提取物具有美白保湿的生物活性。
发明内容
本发明的目的在于提供一种含有水仙花提取物的护肤品，该护肤品可提高皮肤的锁水能力，同时可降低皮肤黑色素含量，具有美白保湿的效果。
本发明的目的是这样实现的：
一种美白保湿护肤品，由植物提取物、护肤基质和去离子水制备而成，所述的植物提取物为水仙花花瓣的氯仿提取部位。
优选地，如上所述的美白保湿护肤品，以重量百分比计，其中的植物提取物组分含量为2～10％，护肤基质组分含量为25～50％，余量为去离子水。
进一步优选地，如上所述的美白保湿护肤品，其中的植物提取物按如下方法制备而成：以水仙花的花瓣作为原料，加入体积份数为93％-98％的乙醇溶液中浸泡12-48h，然后加热回流提取1-4次，每次回流提取时间为1-5h，提取液过滤，滤液经回收乙醇后浓缩成浸膏，加水溶解，用氯仿萃取至水相呈无色，所得氯仿萃取液经回收溶剂后干燥，即得。
本发明人对多种植物的有效部位进行提取，并测试其对皮肤的保湿和美白性能。结果发现，水仙花的水提物、醇提物及正己烷提取物的美白保湿效果不明显，而氯仿提取部位不仅可以降低皮肤黑色素含量，具有美白的功效，而且能有效锁住水分，增强皮肤的保湿能力。基于上述研究结果，本发明的另一个目的在于提供一种产品用途，即：水仙花花瓣的氯仿提取部位在制备美白护肤品中的应用；或者，水仙花花瓣的氯仿提取部位在制备保湿护肤品中的应用。
与现有技术相比，本发明提供的美白护肤品效果显著，可增强皮肤的锁水能力，降低皮肤黑色素含量，具有美白保湿的功效；同时，产品对皮肤无刺激性，安全可靠。
附图说明
图1：水仙花提取物护肤霜降低黑色素含量的效果。
图2：水仙花提取物护肤霜提高皮肤水分含量的效果。
具体实施方式
以下是本发明水仙花氯仿提取部位的制备实施例和效果试验例，对本发明的技术方案和技术效果做进一步说明和解释。然而，本发明的实施例仅仅是用于解释本发明，而不是对本发明的限制，在本发明的构思前提下对如下制备方法的简单改进都属于本发明要求保护的范围。
实施例1 水仙花氯仿提取部位的制备
取水仙花的干燥花瓣1.16kg，用12L体积份数为95％乙醇溶液浸泡24h后，加热回流提取3次，每次提取时间为2h，合并提取液，过滤，滤液经回收乙醇后浓缩成浸膏，加800mL水溶解，用氯仿进行等体积萃取多次至提取液无色，所得氯仿萃取液经回收溶剂后干燥，粉碎过100目筛，得水仙花氯仿提取部位干粉。
实施例2 水仙花提取物护肤霜的制备
（1）称取辛酸癸酸甘油酯70g，硬脂酸50g，二甲基硅氧烷50g，棕榈酸异丙酯40g，单甘脂10g和尼泊金甲酯1g，混合，加热至80℃，熔化搅拌均匀，作为油相；
（2）量取600ml去离子水，加入1,2-丙二醇80ml和三乙醇胺10ml，搅拌使混匀，将实施例1制备的水仙花氯仿提取部位干粉3.5g加入混合溶液中，加热至85℃，搅拌溶解均匀，作为水相；
（3）将油相和水相加到乳化锅中，搅拌均匀，乳化均质6min，搅拌冷却至50℃时，加入1g香精，搅拌均匀，冷却至38℃，即为水仙花提取物护肤霜。将水相中的水仙花提取物以去离子水代替，按照相同的方法制得空白对照护肤霜样品。
实施例3 水仙花提取物护肤霜的皮肤美白性能测试实验
选择10名皮肤健康的志愿者左右前臂内侧3cm×3cm区域为受试部位，一侧涂抹实施例2制备的待测样品，另一侧涂抹空白对照样品。每天早、晚各使用1次，共4周，涂抹后避免被水洗去。分别在使用前和每隔1周后用德国CK电子公司生产的皮肤黑色素测试仪检查皮肤中的黑色素含量。按下式计算皮肤黑色素变化率：黑色素变化率=涂抹样品后测得的皮肤黑色素含量 /涂抹样品前测得的皮肤黑色素含量×100％。
皮肤的颜色主要取决于人体皮肤中黑色素的含量，通过对皮肤色素的含量检测能反映皮肤老化程度及化妆品的美白效果。图1为使用水仙花提取物护肤霜和对照护肤霜后人体皮肤黑色素的变化情况。由图1可知，随着使用时间的延长，空白对照护肤霜的受试区域黑色素含量无显著变化，黑色素含量比涂抹前有小量减少，这是由于人体自身新陈代谢及环境因素导致的。而涂抹水仙花提取物护肤霜的受试区域黑色素含量随着使用时间的延长而逐渐减少，这是由于水仙花提取物具有减少脂质过氧化产物丙二醛的含量，提高皮肤中SOD活性的作用。因此，在膏霜配方中添加适量的水仙花氯仿部位提取物可以降低皮肤黑色素含量，具有美白的功效。
实施例4 水仙花提取物护肤霜的保湿性能测试实验
选择10名皮肤健康、无化妆品过敏史的志愿者。在试验前，洗净左右前臂，晾干，在22℃，相对湿度为55％的恒温恒湿室里稳定30min，待皮肤温度和湿度与环境达到平衡后，于左右前臂上各划出3cm×3cm的试验区域，左臂为空白对照样品涂抹区、右臂为待测样品涂抹区。使用德国CK电子公司生产的CM825皮肤水分测试探头测定各部位的角质层水分含量，取平均值作为测试值。然后取0.1g样品（实施例2制备的水仙花提取物护肤霜或空白对照护肤霜）涂抹于受试部位，于60，120，180和240 min后，同法测量皮肤角质层水分含量。
水分是皮肤表皮角质层重要的塑形物质之一，皮肤衰老时表皮角质层变薄，角质层中天然保湿因子含量减少，皮肤水合能力降低，皮肤水分丧失加快。通过对皮肤水分的测定可以间接反映皮肤衰老的程度以及抗衰老化妆品的功效。图2为使用水仙花提取物护肤霜和对照护肤霜后，皮肤保湿性的变化情况。由图2的试验结果可知，随着时间的延长，空白对照护肤霜的受试区域含水量变化较小，水分含量比涂抹前稍大，这是由于皮肤表面维持自身水分平衡导致的；而涂抹水仙花提取物护肤霜的受试区域含水量是随着时间的延长先提高后缓慢降低的，这是由于水仙花提取物可以给皮肤表面补充水分，而且还能在皮肤表面形成一层膜，降低水分蒸发的速度。因此，在膏霜配方中添加适量的水仙花氯仿提取物可以增强皮肤的保湿能力。
Claims (5)
1.一种美白保湿护肤品，由植物提取物、护肤基质和去离子水制备而成，其特征在于：所述的植物提取物为水仙花花瓣的氯仿提取部位。
2.根据权利要求1所述的美白保湿护肤品，其特征在于：以重量百分比计，所述的植物提取物组分为2～10％，护肤基质组分为25～50％，余量为去离子水。
3.根据权利要求1或2所述的美白保湿护肤品，其特征在于：所述的植物提取物按如下方法制备而成：以水仙花的花瓣作为原料，加入体积份数为93％-98％的乙醇溶液中浸泡12-48h，然后加热回流提取1-4次，每次回流提取时间为1-5h，提取液过滤，滤液经回收乙醇后浓缩成浸膏，加水溶解，用氯仿萃取至水相呈无色，所得氯仿萃取液经回收溶剂后干燥，即得。
4.水仙花花瓣的氯仿提取部位在制备美白护肤品中的应用。
5.水仙花花瓣的氯仿提取部位在制备保湿护肤品中的应用。
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| CN107648131A (zh) * | 2017-11-24 | 2018-02-02 | 郑家伟 | 一种含有天然植物提取物的美白护肤品 |
| CN108078838A (zh) * | 2017-12-18 | 2018-05-29 | 东莞俏美肌生物科技有限公司 | 美白保湿护肤品 |
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| CN107648131A (zh) * | 2017-11-24 | 2018-02-02 | 郑家伟 | 一种含有天然植物提取物的美白护肤品 |
| CN107648131B (zh) * | 2017-11-24 | 2020-06-02 | 烟台市华昕生物医药科技有限公司 | 一种含有天然植物提取物的美白护肤品 |
| CN111329812A (zh) * | 2017-11-24 | 2020-06-26 | 郑家伟 | 一种含有天然植物提取物的美白护肤品 |
| CN108078838A (zh) * | 2017-12-18 | 2018-05-29 | 东莞俏美肌生物科技有限公司 | 美白保湿护肤品 |
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