CN104645238A - Traditional Chinese medicine composition for promoting lactation after delivery and preparation method of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition for promoting lactation after delivery and preparation method of traditional Chinese medicine composition Download PDFInfo
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Abstract
The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for promoting lactation after delivery. The traditional Chinese medicine composition is prepared from the following components: liquorice, tetrapanax papyriferus, angelica sinensis, pangolin, pericarpium citri reticulatae viride, antler glue, astragalus membranaceus, cowherb seed, daylily root, radix bupleuri, costusroot, white paeony root, codonopsis pilosula, euphorbia maculate, herba leonuri, mongolian snake gourd root, uniflower swisscentaury root, earthworm, szechwan Chinaberry fruit, tribulus terrestris, malva neglecta, ligusticum wallichii, jujube and turmeric. The traditional Chinese medicine composition has the efficacies of dredging collaterals, activating blood circulation, regulating menstruation, inducing diuresis, reducing swelling and promoting lactation milk; the medicines are assisted by jujube, turmeric and cowherb seed to play roles in promoting circulation of blood, promoting lactation and harmonizing the medicines. Medicines for promoting lactation are adopted as main materials; and the medicines for nourishing blood and dispersing blood stasis are adopted as auxiliary materials to form a reasonable prescription for treating postpartum milk impassability, breast distension, acute mastitis, blood stasis pain, weakness and debilitation.
Description
Technical field
The invention belongs to technical field of traditional Chinese pharmacology, be specifically related to Chinese medicine composition of lactogenesis in a kind of puerperal and preparation method thereof.
Background technology
Total institute is known, for ewborn infant, breast milk is the most natural and optimal food, mother and sons' emotion can also be promoted by breast feeding simultaneously, most importantly breast milk is more easy to digest than formulas, this is because containing a kind of enzyme that baby can be helped to digest in breast milk, compared with milk, breast milk forms softer curdled milk in the stomach of baby, can quickly assimilate by body system, although the content of protein is lower than cattle milk in breast milk, but be all almost that baby can utilize, on the contrary, in milk, the protein of nearly half is taken as refuse and has discharged the external of baby, equally, breast-fed babies also absorb better to ferrum and zinc.
But along with the quickening of people's rhythm of life and the increase of life stress, in puerperal, most of puerpera occurs that milk is few or without the phenomenon of milk for various reasons.The method of current lactogenic mainly through in, massage and lactogenic decoction.The medicine of lactogenesis stimulating milk secretion is few in the market, pharmaceutical compositions is dull, the final drug in anemia of pregnant woman puerperal can only tackle separately certain pathological changes in puerperal, all symptoms that anemia of pregnant woman occurs puerperal can not be contained, the lactogenesis that market is sold, CUIRU PIAN effect are not very desirable, can not fundamentally regulate puerpera's physiological to restore, promote the function of uterine contraction and lactication phase pituitary prolactin antagonist, the baby of domestic about 40-50% is nearly in the situation of hypogalactia or agalactia at present.
" tire produces heart method " cloud: " puerpera's punching appoints blood prosperous, taste gas strong then breast foot ".Xue Li vegetarian cloud: " blood person, essence-QI from water and grain also, and adjusts the five internal organs, and spilling old six internal organs, then turn to essence man, married woman is milk, and lower is the sea of blood ".As for the reason of puerperal hypogalactia, " Complete Effective Prescriptions for Women " cloud: " married woman's milk is QI and blood, if vigour is weak, then milk is short of; Primipara's breast fire is glad swollen, and this breast end is logical; If anger breast goes out, this wind-heat of liver channel; If produce agalactia repeatly, this is exhaustion of thin fluid "." Confucian's Duties to Their Parents " is said: " married woman Ben Sheng agalactia person do not control.Or because of sad anger pent-up of crying, gas overflows inaccessible, so that alactation ".
Summary of the invention
In order to overcome deficiency of the prior art, the invention provides the Chinese medicine composition of lactogenesis in a kind of puerperal.
In order to solve the problems of the technologies described above, the technical solution used in the present invention is as follows: a kind of puerperal lactogenesis Chinese medicine composition, be made up of each component of following parts by weight: Radix Glycyrrhizae 5-20 weight portion; Medulla Tetrapanacis 1-10 weight portion; Radix Angelicae Sinensis 5-20 weight portion; Squama Manis 1-10 weight portion; Pericarpium Citri Reticulatae Viride 1-8 weight portion; Antler gelatin 1-8 weight portion; Radix Astragali 5-15 weight portion; Semen Vaccariae 1-20 weight portion; Radix Hemerocallis 5-20 weight portion; Radix Bupleuri 5-25 weight portion; Radix Aucklandiae 1-15 weight portion; Radix Paeoniae Alba 1-20 weight portion; Radix Codonopsis 1-6 weight portion; Herba Euphorbiae supinae 5-20 weight portion; Herba Leonuri 5-20 weight portion; Radix Trichosanthis 1-15 weight portion; Leak calabash 5-20 weight portion; Pheretima 1-10 weight portion; Fructus Toosendan 1-20 weight portion; Fructus Tribuli 1-25 weight portion; Dawrf mallow 1-20 weight portion; Rhizoma Chuanxiong 1-20 weight portion; Fructus Jujubae 1-20 weight portion; Rhizoma Curcumae Longae 2-8 weight portion.
Further, the present invention also can be made up of each component of following parts by weight: Radix Glycyrrhizae 5-15 weight portion; Medulla Tetrapanacis 1-8 weight portion; Radix Angelicae Sinensis 5-15 weight portion; Squama Manis 1-8 weight portion; Pericarpium Citri Reticulatae Viride 1-8 weight portion; Antler gelatin 1-6 weight portion; Radix Astragali 5-10 weight portion; Semen Vaccariae 1-15 weight portion; Radix Hemerocallis 5-15 weight portion; Radix Bupleuri 5-15 weight portion; Radix Aucklandiae 1-10 weight portion; Radix Paeoniae Alba 1-20 weight portion; Radix Codonopsis 1-6 weight portion; Herba Euphorbiae supinae 5-20 weight portion; Herba Leonuri 5-15 weight portion; Radix Trichosanthis 1-15 weight portion; Leak calabash 5-20 weight portion; Pheretima 1-10 weight portion; Fructus Toosendan 1-10 weight portion; Fructus Tribuli 1-20 weight portion; Dawrf mallow 1-15 weight portion; Rhizoma Chuanxiong 1-15 weight portion; Fructus Jujubae 1-15 weight portion; Rhizoma Curcumae Longae 2-8 weight portion.
Further, the present invention also can be made up of each component of following parts by weight: Radix Glycyrrhizae 5-10 weight portion; Medulla Tetrapanacis 1-5 weight portion; Radix Angelicae Sinensis 5-10 weight portion; Squama Manis 1-5 weight portion; Pericarpium Citri Reticulatae Viride 1-5 weight portion; Antler gelatin 1-3 weight portion; Radix Astragali 5-8 weight portion; Semen Vaccariae 1-10 weight portion; Radix Hemerocallis 5-7 weight portion; Radix Bupleuri 5-8 weight portion; Radix Aucklandiae 1-8 weight portion; Radix Paeoniae Alba 1-6 weight portion; Radix Codonopsis 1-6 weight portion; Herba Euphorbiae supinae 5-10 weight portion; Herba Leonuri 5-10 weight portion; Radix Trichosanthis 1-10 weight portion; Leak calabash 5-10 weight portion; Pheretima 1-10 weight portion; Fructus Toosendan 1-10 weight portion; Fructus Tribuli 1-10 weight portion; Dawrf mallow 1-15 weight portion; Rhizoma Chuanxiong 1-10 weight portion; Fructus Jujubae 1-10 weight portion; Rhizoma Curcumae Longae 2-5 weight portion.
Further, present invention also offers the preparation method of the Chinese medicine composition of lactogenesis in a kind of puerperal, the first step, the Radix Glycyrrhizae got ready, Medulla Tetrapanacis, Radix Angelicae Sinensis, Squama Manis, Pericarpium Citri Reticulatae Viride, the Radix Astragali, Semen Vaccariae, Radix Hemerocallis, Radix Bupleuri, the Radix Aucklandiae, the Radix Paeoniae Alba, Radix Codonopsis, Herba Euphorbiae supinae, Herba Leonuri, Radix Trichosanthis, leakage calabash, Pheretima, Fructus Toosendan, Fructus Tribuli, dawrf mallow, Rhizoma Chuanxiong, Fructus Jujubae, Rhizoma Curcumae Longae are put into medicine pot, then, add 5-20 water doubly in medicine pot after, above medical material is soaked 30 ~ 120 minutes;
Second step, heats first step medicine pot with moderate heat, and after the water boiling in medicine pot, add antler gelatin, be uniformly mixed, slow fire slowly decocts 30-120 minute, pours out the medicine juice in medicine pot;
3rd step, with moderate heat to medicine pot heats after again adding 5-10 water doubly in medicine pot, and after the water boiling in medicine pot, slow fire slowly decocts 20-60 minute, then pours out the medicine juice in medicine pot; Merge twice medicine juice, by macroporous adsorptive resins, the weight ratio of resin and medicine juice is 1: 1, washes with water to after closely colourless, then uses ethanol elution, collects ethanol elution, decompression recycling ethanol, and heating is concentrated into paste, makes moisture be down to 30%;
4th step, by the thick paste of the 3rd step gained, adds the starch of 2.6 times of volumes, stirs, and then adds the ethanol that volume ratio accounts for 60-95%, stirs into uniform soft material; Granule is made again through 12 mesh sieves, then by gained granule in 45 DEG C of Uniform Ventilation dryings, granulate;
5th step, packs: by quantitatively being packed by electuary granule of often wrapping.
The pharmacological action of drug component of the present invention is specific as follows:
Radix Glycyrrhizae
Nature and flavor: sweet are flat.
Gui Jing: GUIXIN, lung, spleen, stomach warp.
Function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Medulla Tetrapanacis
Nature and flavor: sweet, light, are slightly cold.
Gui Jing: attach to the lung and stomach meridians.
Function cures mainly: clearing away heat and promoting diuresis, ventilation stimulating milk secretion.For hygropyrexia dark coloured urine, the puckery pain of gonorrhea, edema oliguria, agalactia.
Radix Angelicae Sinensis
Nature and flavor: sweet, acrid, warm.
Gui Jing: return liver, the heart, spleen channel.
Function cures mainly: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
Squama Manis
Nature and flavor: salty, are slightly cold.
Gui Jing: return liver, stomach warp.
Function cures mainly: stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis, expel wind to dredge collateral.For Jing Bi WEIJIA, galactostasis, carbuncle sore tumefacting virus, arthralgia, numbness contracture.
Pericarpium Citri Reticulatae Viride
Nature and flavor: bitter, pungent, temperature.
Gui Jing: return liver, gallbladder, stomach warp.
Function cures mainly: soothing the liver dispelling the stagnated QI, removing food stagnancyization is stagnant.For distending pain in the chest and hypochondrium, hernia, nodule in the breast, acute mastitis, abdominal pain due to retention of food.
Antler gelatin
Function cures mainly: tonifying YANG supplementing the brain, and spermatogenesis mends marrow.Main myasthenia of limbs, soreness of the waist and knees, impotence due to deficiency of the kidney, woman uterine bleeding leukorrhagia.
The Radix Astragali
Nature and flavor: sweet, temperature.
Gui Jing: return lung, spleen channel.
Function cures mainly: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Semen Vaccariae
Nature and flavor: bitter are flat.
Gui Jing: return liver, stomach warp.
Function cures mainly: promoting blood circulation to restore menstrual flow, and stimulating milk secretion is subsided a swelling.For agalactia, amenorrhea, dysmenorrhea, acute mastitis swells and ache.
Radix Hemerocallis
Nature and flavor: sweet; Cool; Poisonous
Gui Jing: spleen; Liver; Urinary bladder channel
Function cures mainly: clearing away heat-damp and promoting diuresis; Cooling blood for hemostasis; Removing toxic substances and promoting subsidence of swelling.Main jaundice; Edema; Stranguria with turbid discharge; Leukorrhagia; Epistaxis; Have blood in stool; Metrorrhagia; Acute mastitis; Acute mastitis; Galactostasis.
Radix Bupleuri
Nature and flavor: bitter, are slightly cold.
Gui Jing: return liver, gallbladder meridian.
Function cures mainly: reconciling superficies and interior, soothing the liver, yang invigorating.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.
The Radix Aucklandiae
Nature and flavor: pungent, bitter, temperature.
Gui Jing: return spleen, stomach, large intestine, three burnt, gallbladder meridians.
Function cures mainly: promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.For breast gastral cavity distending pain, heavy after dysentery, food stagnation does not disappear, anorexia.The real intestinal antidiarrheal of Radix Aucklandiae (roasted).For stomachache of having loose bowels.
The Radix Paeoniae Alba
Nature and flavor: bitter, sour, are slightly cold.
Gui Jing: return liver, spleen channel.
Function cures mainly: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
Radix Codonopsis
Nature and flavor: sweet are flat.
Gui Jing: return spleen, lung meridian.
Function cures mainly: invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.
Herba Euphorbiae supinae
Nature and flavor: " will planted by Tianmu Mountains of Zhejiang Province medicine ": " pungent, flat.″
Function cures mainly: hemostasis, clearing away damp-heat, lactogenesis.To harness the Yellow River subcutaneous ulcer, have loose bowels, infantile malnutrition, dysentery, hematuria, metrorrhagia, traumatic hemorrhage, milk is few, carbuncle sore tumefacting virus.
Herba Leonuri
Nature and flavor: bitter, pungent, are slightly cold.
Gui Jing: return liver, pericardium channel.
Function cures mainly: promoting blood flow to regulate menstruation, inducing diuresis to remove edema.For menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema oliguria; Acute nephritis edema.
Radix Trichosanthis
Nature and flavor: sweet, micro-hardship, is slightly cold.
Gui Jing: attach to the lung and stomach meridians.
Function cures mainly: clearing away heat and promoting production of body fluid, detumescence and apocenosis.For calentura excessive thirst, lung-heat type cough, interior-heat is quenched one's thirst, sore swollen toxin.
Leak calabash
Nature and flavor: " herbal classic ": " bitter in the mouth is salty, cold.”
Gui Jing: enter stomach, large intestine channel.
Function: heat-clearing and toxic substances removing, eliminating carbuncle, stimulating milk secretion, relaxing muscles and tendons is promoted blood circulation, and swells and ache for acute mastitis, carbuncle carbuncle on the back, scrofula sore, galactostasis, arthralgia chiefly caused by damp pathogen contracture, arthralgia, toxic-heat and blood stasis, bleeding hemorrhoids.
Pheretima
Nature and flavor: salty, cold.
Gui Jing: return liver, spleen, urinary bladder channel.
Function cures mainly: heat clearing away is calmed the frightened, and dredging collateral, relievings asthma, diuresis.For unconsciousness due to high fever, infantile convulsion is twitched, arthralgia, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, hypertension.
Fructus Toosendan
Nature and flavor: bitter, cold; Slightly poisonous.
Gui Jing: return liver, small intestinal, urinary bladder channel.
Function cures mainly: soothing liver-QI promoting the circulation of QI to relieve pain, anthelmintic.For the breast side of body, abdominal distention, colic, abdominal pain due to worm stagnation.
Fructus Tribuli
Nature and flavor: pungent, bitter, tepor; Slightly poisonous.
Gui Jing: return Liver Channel.
Function cures mainly: suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, and improving eyesight is antipruritic.Dizzy for having a headache, distending pain in the chest and hypochondrium, breast closes acute mastitis, cataract, rubella pruritus.
Dawrf mallow
Nature and flavor: sweet; Temperature
Gui Jing: spleen; Lung meridian
Function cures mainly: QI invigorating hidroschesis; Diuretic lactogenesis; The evacuation of pus of holder skin ulcer.Main fatigue and weakness; Visceroptosis; Cough due to deficiency of the lung; Spontaneous sweating; Edema; Hypogalactia; Metrorrhagia; Carbuncle difficulty is burst; After bursting, pus is rare; Open sore part difficulty is closed.
Rhizoma Chuanxiong
Nature and flavor: pungent, temperature.
Gui Jing: return liver, gallbladder, pericardium channel.
Function cures mainly: blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Fructus Jujubae
Nature and flavor: sweet, temperature.
Gui Jing: return spleen, stomach warp.
Function cures mainly: really (Fructus Jujubae): invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.For insufficiency of the spleen lack of appetite, weak loose stool, woman hysteria.Bark: antiinflammatory, hemostasis, antidiarrheal.For tracheitis, enteritis, dysentery, metrorrhagia; Traumatic hemorrhage is controlled in external.Root: circulation of qi promoting, invigorates blood circulation, regulating menstruation.For menoxenia, redly to collapse, leucorrhea.
Rhizoma Curcumae Longae
Nature and flavor: pungent, bitter, temperature.
Gui Jing: return spleen, Liver Channel.
Function cures mainly: removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia.For the twinge of the breast side of body, amenorrhea ， WEIJIA, rheumatism shoulder arm pain, tumbling and swelling.
In sum, effect that the present invention has that dredging collateral is invigorated blood circulation, promoting blood flow to regulate menstruation, inducing diuresis to remove edema, delactation stimulate the secretion of milk, adopts Fructus Jujubae, Rhizoma Curcumae Longae, Semen Vaccariae to assist each taste medicine jointly to play promoting the circulation of blood stimulating milk secretion, is in harmonious proportion the use of each medicine.The present invention is to pass into, and hemopoietic blood stasis dispelling medicine is auxiliary, constitutes treatment galactostasis in puerperal, mammary swelling, acute mastitis, blood stasis are had a pain, the empty weak reasonable prescription of body.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of effective ingredient of the present invention and parts by weight are: a kind of puerperal lactogenesis Chinese medicine composition, Medulla Tetrapanacis 1 weight portion; Radix Angelicae Sinensis 5 weight portion; Squama Manis 1 weight portion; Pericarpium Citri Reticulatae Viride 1 weight portion; Antler gelatin 1 weight portion; The Radix Astragali 5 weight portion; Semen Vaccariae 10 weight portion; Radix Hemerocallis 5 weight portion; Radix Bupleuri 5 weight portion; The Radix Aucklandiae 5 weight portion; The Radix Paeoniae Alba 2 weight portion; Radix Codonopsis 2 weight portion; Herba Euphorbiae supinae 5 weight portion; Herba Leonuri 5 weight portion; Radix Trichosanthis 1 weight portion; Leak calabash 5 weight portion; Pheretima 1 weight portion; Fructus Toosendan 1 weight portion; Fructus Tribuli 2 weight portion; Dawrf mallow 10 weight portion; Rhizoma Chuanxiong 2 weight portion; Fructus Jujubae 5 weight portion; Rhizoma Curcumae Longae 2 weight portion.
Further, the preparation method of Chinese medicine composition, the first step, the Radix Glycyrrhizae got ready, Medulla Tetrapanacis, Radix Angelicae Sinensis, Squama Manis, Pericarpium Citri Reticulatae Viride, the Radix Astragali, Semen Vaccariae, Radix Hemerocallis, Radix Bupleuri, the Radix Aucklandiae, the Radix Paeoniae Alba, Radix Codonopsis, Herba Euphorbiae supinae, Herba Leonuri, Radix Trichosanthis, leakage calabash, Pheretima, Fructus Toosendan, Fructus Tribuli, dawrf mallow, Rhizoma Chuanxiong, Fructus Jujubae, Rhizoma Curcumae Longae are put into medicine pot, then, after adding the water of 10 times in medicine pot, above medical material is soaked 120 minutes;
Second step, heats first step medicine pot with moderate heat, and after the water boiling in medicine pot, add antler gelatin, be uniformly mixed, slow fire slowly decocts 30 minutes, pours out the medicine juice in medicine pot;
3rd step, with moderate heat to medicine pot heats after again adding the water of 5 times in medicine pot, and after the water boiling in medicine pot, slow fire slowly decocts 20 minutes, then pours out the medicine juice in medicine pot; Merge twice medicine juice, by macroporous adsorptive resins, the weight ratio of resin and medicine juice is 1: 1, washes with water to after closely colourless, then uses ethanol elution, collects ethanol elution, decompression recycling ethanol, and heating is concentrated into paste, makes moisture be down to 30%;
4th step, by the thick paste of the 3rd step gained, adds the starch of 2.6 times of volumes, stirs, and then adds the ethanol that volume ratio accounts for 60%, stirs into uniform soft material; Granule is made again through 12 mesh sieves, then by gained granule in 45 DEG C of Uniform Ventilation dryings, granulate;
5th step, packs: by quantitatively being packed by electuary granule of often wrapping.
Embodiment 2
The raw material composition of effective ingredient of the present invention and parts by weight are: Medulla Tetrapanacis 5 weight portion; Radix Angelicae Sinensis 5 weight portion; Squama Manis 1 weight portion; Pericarpium Citri Reticulatae Viride 5 weight portion; Antler gelatin 1 weight portion; The Radix Astragali 8 weight portion; Semen Vaccariae 10 weight portion; Radix Hemerocallis 7 weight portion; Radix Bupleuri 8 weight portion; The Radix Aucklandiae 8 weight portion; The Radix Paeoniae Alba 5 weight portion; Radix Codonopsis 3 weight portion; Herba Euphorbiae supinae 6 weight portion; Herba Leonuri 8 weight portion; Radix Trichosanthis 3 weight portion; Leak calabash 5 weight portion; Pheretima 3 weight portion; Fructus Toosendan 4 weight portion; Fructus Tribuli 2 weight portion; Dawrf mallow 6 weight portion; Rhizoma Chuanxiong 2 weight portion; Fructus Jujubae 10 weight portion; Rhizoma Curcumae Longae 2 weight portion.
Further, the preparation method of Chinese medicine composition, the first step, the Radix Glycyrrhizae got ready, Medulla Tetrapanacis, Radix Angelicae Sinensis, Squama Manis, Pericarpium Citri Reticulatae Viride, the Radix Astragali, Semen Vaccariae, Radix Hemerocallis, Radix Bupleuri, the Radix Aucklandiae, the Radix Paeoniae Alba, Radix Codonopsis, Herba Euphorbiae supinae, Herba Leonuri, Radix Trichosanthis, leakage calabash, Pheretima, Fructus Toosendan, Fructus Tribuli, dawrf mallow, Rhizoma Chuanxiong, Fructus Jujubae, Rhizoma Curcumae Longae are put into medicine pot, then, after adding the water of 5 times in medicine pot, above medical material is soaked 30 minutes;
Second step, heats first step medicine pot with moderate heat, and after the water boiling in medicine pot, add antler gelatin, be uniformly mixed, slow fire slowly decocts 50 minutes, pours out the medicine juice in medicine pot;
3rd step, with moderate heat to medicine pot heats after again adding the water of 5 times in medicine pot, and after the water boiling in medicine pot, slow fire slowly decocts 60 minutes, then pours out the medicine juice in medicine pot; Merge twice medicine juice, by macroporous adsorptive resins, the weight ratio of resin and medicine juice is 1: 1, washes with water to after closely colourless, then uses ethanol elution, collects ethanol elution, decompression recycling ethanol, and heating is concentrated into paste, makes moisture be down to 30%;
4th step, by the thick paste of the 3rd step gained, adds the starch of 2.6 times of volumes, stirs, and then adds the ethanol that volume ratio accounts for 60%, stirs into uniform soft material; Granule is made again through 12 mesh sieves, then by gained granule in 45 DEG C of Uniform Ventilation dryings, granulate;
5th step, packs: by quantitatively being packed by electuary granule of often wrapping.
Embodiment 3
The raw material composition of effective ingredient of the present invention and parts by weight are: Medulla Tetrapanacis 1 weight portion; Radix Angelicae Sinensis 5 weight portion; Squama Manis 3 weight portion; Pericarpium Citri Reticulatae Viride 3 weight portion; Antler gelatin 3 weight portion; The Radix Astragali 5 weight portion; Semen Vaccariae 8 weight portion; Radix Hemerocallis 6 weight portion; Radix Bupleuri 7 weight portion; The Radix Aucklandiae 7 weight portion; The Radix Paeoniae Alba 5 weight portion; Radix Codonopsis 4 weight portion; Herba Euphorbiae supinae 8 weight portion; Herba Leonuri 8 weight portion; Radix Trichosanthis 8 weight portion; Leak calabash 10 weight portion; Pheretima 10 weight portion; Fructus Toosendan 4 weight portion; Fructus Tribuli 6 weight portion; Dawrf mallow 10 weight portion; Rhizoma Chuanxiong 10 weight portion; Fructus Jujubae 10 weight portion; Rhizoma Curcumae Longae 3 weight portion.
The preparation method of above Chinese medicine composition, the first step, the Radix Glycyrrhizae got ready, Medulla Tetrapanacis, Radix Angelicae Sinensis, Squama Manis, Pericarpium Citri Reticulatae Viride, the Radix Astragali, Semen Vaccariae, Radix Hemerocallis, Radix Bupleuri, the Radix Aucklandiae, the Radix Paeoniae Alba, Radix Codonopsis, Herba Euphorbiae supinae, Herba Leonuri, Radix Trichosanthis, leakage calabash, Pheretima, Fructus Toosendan, Fructus Tribuli, dawrf mallow, Rhizoma Chuanxiong, Fructus Jujubae, Rhizoma Curcumae Longae are put into medicine pot, then, after adding the water of 7 times in medicine pot, above medical material is soaked 70 minutes;
Second step, heats first step medicine pot with moderate heat, and after the water boiling in medicine pot, add antler gelatin, be uniformly mixed, slow fire slowly decocts 30 minutes, pours out the medicine juice in medicine pot;
3rd step, with moderate heat to medicine pot heats after again adding the water of 10 times in medicine pot, and after the water boiling in medicine pot, slow fire slowly decocts 60 minutes, then pours out the medicine juice in medicine pot; Merge twice medicine juice, by macroporous adsorptive resins, the weight ratio of resin and medicine juice is 1: 1, washes with water to after closely colourless, then uses ethanol elution, collects ethanol elution, decompression recycling ethanol, and heating is concentrated into paste, makes moisture be down to 30%;
4th step, by the thick paste of the 3rd step gained, adds the starch of 2.6 times of volumes, stirs, and then adds the ethanol that volume ratio accounts for 95%, stirs into uniform soft material; Granule is made again through 12 mesh sieves, then by gained granule in 45 DEG C of Uniform Ventilation dryings, granulate;
5th step, packs: by quantitatively being packed by electuary granule of often wrapping.
Embodiment 4
The raw material composition of effective ingredient of the present invention and parts by weight are: Medulla Tetrapanacis 1.5 weight portion; Radix Angelicae Sinensis 6.3 weight portion; Squama Manis 1.2 weight portion; Pericarpium Citri Reticulatae Viride 2.6 weight portion; Antler gelatin 1 weight portion; The Radix Astragali 4.5 weight portion; Semen Vaccariae 2.6 weight portion; Radix Hemerocallis 6.3 weight portion; Radix Bupleuri 5.7 weight portion; The Radix Aucklandiae 2.4 weight portion; The Radix Paeoniae Alba 3.7 weight portion; Radix Codonopsis 1 weight portion; Herba Euphorbiae supinae 5 weight portion; Herba Leonuri 5 weight portion; Radix Trichosanthis 1.2 weight portion; Leak calabash 7.5 weight portion; Pheretima 1 weight portion; Fructus Toosendan 4.3 weight portion; Fructus Tribuli 5.7 weight portion; Dawrf mallow 10 weight portion; Rhizoma Chuanxiong 10 weight portion; Fructus Jujubae 20 weight portion; Rhizoma Curcumae Longae 2.6 weight.
The preparation method of above Chinese medicine composition, the first step, the Radix Glycyrrhizae got ready, Medulla Tetrapanacis, Radix Angelicae Sinensis, Squama Manis, Pericarpium Citri Reticulatae Viride, the Radix Astragali, Semen Vaccariae, Radix Hemerocallis, Radix Bupleuri, the Radix Aucklandiae, the Radix Paeoniae Alba, Radix Codonopsis, Herba Euphorbiae supinae, Herba Leonuri, Radix Trichosanthis, leakage calabash, Pheretima, Fructus Toosendan, Fructus Tribuli, dawrf mallow, Rhizoma Chuanxiong, Fructus Jujubae, Rhizoma Curcumae Longae are put into medicine pot, then, after adding the water of 20 times in medicine pot, above medical material is soaked 120 minutes;
Second step, heats first step medicine pot with moderate heat, and after the water boiling in medicine pot, add antler gelatin, be uniformly mixed, slow fire slowly decocts 120 minutes, pours out the medicine juice in medicine pot;
3rd step, with moderate heat to medicine pot heats after again adding the water of 10 times in medicine pot, and after the water boiling in medicine pot, slow fire slowly decocts 60 minutes, then pours out the medicine juice in medicine pot; Merge twice medicine juice, by macroporous adsorptive resins, the weight ratio of resin and medicine juice is 1: 1, washes with water to after closely colourless, then uses ethanol elution, collects ethanol elution, decompression recycling ethanol, and heating is concentrated into paste, makes moisture be down to 30%;
4th step, by the thick paste of the 3rd step gained, adds the starch of 2.6 times of volumes, stirs, and then adds the ethanol that volume ratio accounts for 60%, stirs into uniform soft material; Granule is made again through 12 mesh sieves, then by gained granule in 45 DEG C of Uniform Ventilation dryings, granulate;
5th step, packs: by quantitatively being packed by electuary granule of often wrapping.
Embodiment 5
The raw material composition of effective ingredient of the present invention and parts by weight are: Medulla Tetrapanacis 3 weight portion; Radix Angelicae Sinensis 5 weight portion; Squama Manis 5 weight portion; Pericarpium Citri Reticulatae Viride 5 weight portion; Antler gelatin 1 weight portion; The Radix Astragali 5 weight portion; Semen Vaccariae 1 weight portion; Radix Hemerocallis 7 weight portion; Radix Bupleuri 5 weight portion; The Radix Aucklandiae 8 weight portion; The Radix Paeoniae Alba 6 weight portion; Radix Codonopsis 6 weight portion; Herba Euphorbiae supinae 10 weight portion; Herba Leonuri 5 weight portion; Radix Trichosanthis 1 weight portion; Leak calabash 5 weight portion; Pheretima 1 weight portion; Fructus Toosendan 1 weight portion; Fructus Tribuli 1 weight portion; Dawrf mallow 15 weight portion; Rhizoma Chuanxiong 10 weight portion; Fructus Jujubae 15 weight portion; Rhizoma Curcumae Longae 5 weight.
The preparation method of above Chinese medicine composition, the first step, the Radix Glycyrrhizae got ready, Medulla Tetrapanacis, Radix Angelicae Sinensis, Squama Manis, Pericarpium Citri Reticulatae Viride, the Radix Astragali, Semen Vaccariae, Radix Hemerocallis, Radix Bupleuri, the Radix Aucklandiae, the Radix Paeoniae Alba, Radix Codonopsis, Herba Euphorbiae supinae, Herba Leonuri, Radix Trichosanthis, leakage calabash, Pheretima, Fructus Toosendan, Fructus Tribuli, dawrf mallow, Rhizoma Chuanxiong, Fructus Jujubae, Rhizoma Curcumae Longae are put into medicine pot, then, after adding the water of 20 times in medicine pot, above medical material is soaked 30 minutes;
Second step, heats first step medicine pot with moderate heat, and after the water boiling in medicine pot, add antler gelatin, be uniformly mixed, slow fire slowly decocts 30 minutes, pours out the medicine juice in medicine pot;
3rd step, with moderate heat to medicine pot heats after again adding the water of 5 times in medicine pot, and after the water boiling in medicine pot, slow fire slowly decocts 20 minutes, then pours out the medicine juice in medicine pot; Merge twice medicine juice, by macroporous adsorptive resins, the weight ratio of resin and medicine juice is 1: 1, washes with water to after closely colourless, then uses ethanol elution, collects ethanol elution, decompression recycling ethanol, and heating is concentrated into paste, makes moisture be down to 30%;
4th step, by the thick paste of the 3rd step gained, adds the starch of 2.6 times of volumes, stirs, and then adds the ethanol that volume ratio accounts for 68%, stirs into uniform soft material; Granule is made again through 12 mesh sieves, then by gained granule in 45 DEG C of Uniform Ventilation dryings, granulate;
5th step, packs: by quantitatively being packed by electuary granule of often wrapping.
Embodiment 6
Toxicity test:
In order to verify safety of the present invention, acute toxicity testing:
The medicine made to embodiment 1 to 5 has carried out white mice acute toxicity testing.The made medicine of embodiment 1 to 5 is to the continuous gavage 7d of mice, and having no white mice has the visible poisoning symptom of naked eyes and death, and the body weight change of white mice, liver, kidney body than all with blank group without significant difference, hematological indices is without obvious change.
Clinical trial:
Therapeutic scheme: take the circumstances into consideration administration according to the state of an illness.
Curative effect judging standard:
Effective: galactopoiesis increases, but inadequate feeding infant;
Effective: galactopoiesis is more, but still inadequate feeding infant;
Good effect: galactopoiesis is a lot, normally can feed baby;
Invalid: galactopoiesis is without change.
Use the Chinese medicinal granule that the embodiment of the present invention 1 provides, three times on the one, surrounding is a course for the treatment of, and use four courses for the treatment of, clinical observation, does not find obvious adverse reaction, and curative effect is in table 1.
| Case load | Effective | Effectively | Good effect | Invalid | Total effective rate |
| 89 | 54 | 22 | 7 | 6 | 94.11％ |
As visible in above-mentioned table 1, the present invention treats gynecological inflammation total effective rate more than 90%, has significant curative effect to lactogenic.
Model case:
Case 1 Liu 35 years old
Clinical symptoms: cut open the belly postpartum breastfeeding time hypogalactia, breast is soft without swollen sense, and milk amount is rare clearly less.And wait disease more slowly with abdominal wound healing.Take the Chinese medicine prepared by the embodiment of the present invention 1, latter two rear QI and blood of taking medicine fills Sheng, and milk amount increases, and abdominal wound healing is good.
Case 2 Zhang 28 years old
Clinical symptoms: after cesarean after one week, without milk, with abdominal pain, puerperal edema, tired, appetite of receiving is few, pale tongue, white and thin fur.Take the Chinese medicine prepared by the embodiment of the present invention 1, after taking medicine latter three days, have a small amount of milk, after continuing to take two weeks, milk fills.
Case 3 king so-and-so 25 years old
Clinical symptoms: hypogalactia after a week after cesarean, breast is soft without swollen sense, and milk amount is rare clearly less, with abdominal pain, puerperal edema.Take the Chinese medicinal granule prepared by the embodiment of the present invention 1,
After taking medicine one week, milk amount increases.
The above; it is only most preferred embodiment of the present invention; not any pro forma restriction is done to the present invention; any those of ordinary skill in the art; do not departing under technical solution of the present invention ambit; utilize the method content of above-mentioned announcement to make many possible variations and modification to technical solution of the present invention, all belong to the scope of claims protection.
Claims (4)
1. puerperal lactogenesis a Chinese medicine composition, it is characterized in that: be made up of each component of following parts by weight: Radix Glycyrrhizae 5-20 weight portion; Medulla Tetrapanacis 1-10 weight portion; Radix Angelicae Sinensis 5-20 weight portion; Squama Manis 1-10 weight portion; Pericarpium Citri Reticulatae Viride 1-8 weight portion; Antler gelatin 1-8 weight portion; Radix Astragali 5-15 weight portion; Semen Vaccariae 1-20 weight portion; Radix Hemerocallis 5-20 weight portion; Radix Bupleuri 5-25 weight portion; Radix Aucklandiae 1-15 weight portion; Radix Paeoniae Alba 1-20 weight portion; Radix Codonopsis 1-6 weight portion; Herba Euphorbiae supinae 5-20 weight portion; Herba Leonuri 5-20 weight portion; Radix Trichosanthis 1-15 weight portion; Leak calabash 5-20 weight portion; Pheretima 1-10 weight portion; Fructus Toosendan 1-20 weight portion; Fructus Tribuli 1-25 weight portion; Dawrf mallow 1-20 weight portion; Rhizoma Chuanxiong 1-20 weight portion; Fructus Jujubae 1-20 weight portion; Rhizoma Curcumae Longae 2-8 weight portion.
2. a kind of puerperal according to claim 1 lactogenesis Chinese medicine composition, it is characterized in that: be made up of each component of following parts by weight: Radix Glycyrrhizae 5-15 weight portion; Medulla Tetrapanacis 1-8 weight portion; Radix Angelicae Sinensis 5-15 weight portion; Squama Manis 1-8 weight portion; Pericarpium Citri Reticulatae Viride 1-8 weight portion; Antler gelatin 1-6 weight portion; Radix Astragali 5-10 weight portion; Semen Vaccariae 1-15 weight portion; Radix Hemerocallis 5-15 weight portion; Radix Bupleuri 5-15 weight portion; Radix Aucklandiae 1-10 weight portion; Radix Paeoniae Alba 1-20 weight portion; Radix Codonopsis 1-6 weight portion; Herba Euphorbiae supinae 5-20 weight portion; Herba Leonuri 5-15 weight portion; Radix Trichosanthis 1-15 weight portion; Leak calabash 5-20 weight portion; Pheretima 1-10 weight portion; Fructus Toosendan 1-10 weight portion; Fructus Tribuli 1-20 weight portion; Dawrf mallow 1-15 weight portion; Rhizoma Chuanxiong 1-15 weight portion; Fructus Jujubae 1-15 weight portion; Rhizoma Curcumae Longae 2-8 weight portion.
3. according to described in claim 1 to 2 a kind of puerperal lactogenesis Chinese medicine composition, it is characterized in that: be made up of each component of following parts by weight: Radix Glycyrrhizae 5-10 weight portion; Medulla Tetrapanacis 1-5 weight portion; Radix Angelicae Sinensis 5-10 weight portion Squama Manis 1-5 weight portion Pericarpium Citri Reticulatae Viride 1-5 weight portion antler gelatin 1-3 weight portion; Radix Astragali 5-8 weight portion; Semen Vaccariae 1-10 weight portion; Radix Hemerocallis 5-7 weight portion; Radix Bupleuri 5-8 weight portion; Radix Aucklandiae 1-8 weight portion; Radix Paeoniae Alba 1-6 weight portion; Radix Codonopsis 1-6 weight portion; Herba Euphorbiae supinae 5-10 weight portion; Herba Leonuri 5-10 weight portion; Radix Trichosanthis 1-10 weight portion; Leak calabash 5-10 weight portion; Pheretima 1-10 weight portion; Fructus Toosendan 1-10 weight portion; Fructus Tribuli 1-10 weight portion; Dawrf mallow 1-15 weight portion; Rhizoma Chuanxiong 1-10 weight portion; Fructus Jujubae 1-10 weight portion; Rhizoma Curcumae Longae 2-5 weight portion.
4. according to claims 1 to 3 a kind of puerperal lactogenesis the preparation method of Chinese medicine composition, it is characterized in that: the first step, the Radix Glycyrrhizae got ready, Medulla Tetrapanacis, Radix Angelicae Sinensis, Squama Manis, Pericarpium Citri Reticulatae Viride, the Radix Astragali, Semen Vaccariae, Radix Hemerocallis, Radix Bupleuri, the Radix Aucklandiae, the Radix Paeoniae Alba, Radix Codonopsis, Herba Euphorbiae supinae, Herba Leonuri, Radix Trichosanthis, leakage calabash, Pheretima, Fructus Toosendan, Fructus Tribuli, dawrf mallow, Rhizoma Chuanxiong, Fructus Jujubae, Rhizoma Curcumae Longae are put into medicine pot, then, add 5-20 water doubly in medicine pot after, above medical material is soaked 30 ~ 120 minutes;
Second step, heats first step medicine pot with moderate heat, and after the water boiling in medicine pot, add antler gelatin, be uniformly mixed, slow fire slowly decocts 30-120 minute, pours out the medicine juice in medicine pot;
3rd step, with moderate heat to medicine pot heats after again adding 5-10 water doubly in medicine pot, and after the water boiling in medicine pot, slow fire slowly decocts 20-60 minute, then pours out the medicine juice in medicine pot; Merge twice medicine juice, by macroporous adsorptive resins, the weight ratio of resin and medicine juice is 1: 1, washes with water to after closely colourless, then uses ethanol elution, collects ethanol elution, decompression recycling ethanol, and heating is concentrated into paste, makes moisture be down to 30%;
4th step, by the thick paste of the 3rd step gained, adds the starch of 2.6 times of volumes, stirs, and then adds the ethanol that volume ratio accounts for 60-95%, stirs into uniform soft material; Granule is made again through 12 mesh sieves, then by gained granule in 45 DEG C of Uniform Ventilation dryings, granulate;
5th step, packs: by quantitatively being packed by electuary granule of often wrapping.
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Application publication date: 20150527 |