CN104644516A - Method for extracting substances from starfish - Google Patents
Method for extracting substances from starfish Download PDFInfo
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- CN104644516A CN104644516A CN201410647646.9A CN201410647646A CN104644516A CN 104644516 A CN104644516 A CN 104644516A CN 201410647646 A CN201410647646 A CN 201410647646A CN 104644516 A CN104644516 A CN 104644516A
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- Prior art keywords
- asterias amurensis
- amurensis lutken
- lutken
- asterias
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- Cosmetics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention provides a method for extracting substances from starfishes, which can successfully extract important components contained in the starfishes, including polysaccharides, ceramides, amino acids and mineral trace elements, and the starfishes extract has multiple maintenance effects, is easy to be absorbed by skin, and can really achieve the effects of moisturizing, whitening, anti-aging, anti-inflammation and the like.
Description
Technical field
The invention relates to the method for extracting substance, particularly obtain the extracting process of extract from Asterias amurensis Lutken.
Background technology
Skin is the maximum organ of human body.Adult skin surface area is about 1.6 square centimeters, and gross weight is about 16% of human body.But along with the change of circumstances, the ultraviolet received by modern and air pollution strengthen day by day, cause skin aging ahead of time, skin basal layer starts to subside, and makes that collagen fabric is out-of-sequence is entangled with, elastic fiber progressively follows the string, and causes the generation of skin surface microgroove and wrinkle.Therefore, concerning modern, how to allow skin continue to distribute youth gloss, allow the operational maintenance of skin, moisturizing more and more come into one's own.
Forming the reason of skin aging has a lot, the part reason that reductions of skin oxygen concentration, free radical injury, collagen protein minimizing, cell turnover slow down, paracytic appearance, skin fat minimizing, Growth of Cells stop, degradation is all skin aging under hormone.For preventing skin aging, common maintenance method is divided into external skin care products, edible nourishing complementary goods, medical and beauty treatment etc.And wherein, external skin care products be the most general, cost is minimum, and because smearing to speckle or crumple zone, impaired skin part can be made to absorb nutrient in the most direct mode, therefore more easily allows user extensively use.
Skin can be divided into epidermal area and skin corium, two kinds of main components of skin corium, i.e. collagen protein and glutinous Polysaccharides.Collagen protein, elastin laminin support the shape of skin, make skin have good elasticity, youth and consolidation; Glutinous polysaccharide is then filled in by the support that fiber is formed, and enough glutinous polysaccharides, in order to keep moisture content in skin here, increase skin gloss.
The maintenance reparation of skin is except the collagen protein of skin corium; supplementing with reparation of epidermal area ceramide is also very important; ceramide is distinctive a kind of oils and fats in horny layer; there is the dual-use function of protection skin and help maintenance moisture content; ceramide can promote skin surface barrier function, reduces moisture loss, maintains skin and to satisfy water degree; reconstituted cell adhesion, the impaired skin with drying of effective maintenance.
Amino acid is the composition of epidermis nature moisturizing factor (Natural Moisturizing Factor), and the number of its content can affect the water holding capacity of skin.And collagen protein and elastin are also all made up of amino acid in skin, glycine (Glycine) is just closely bound up with the synthesis of collagen protein with hydroxyl proline (Hydroxyproline), and therefore compacting of amino acid and skin tenderly with water has positive correlation.
Asterias amurensis Lutken belongs to echinoderm, general Asterias amurensis Lutken tool five tentacles, and the water pipe system on tentacle has the sucker of protrusion, in order to water suction and acquisition food.Asterias amurensis Lutken has rapid regeneration ability, if Asterias amurensis Lutken tentacle is cut off, Asterias amurensis Lutken just can grow back tentacle after a while, and the tentacle itself that minority Asterias amurensis Lutken is cut also can grow up to an Asterias amurensis Lutken.Therefore, the ability of Asterias amurensis Lutken regeneration and repairing is extremely considerable.
The inventor of this case finds that the extract of Asterias amurensis Lutken has its effect, contributes to human body skin regeneration, does one's utmost research, attempt different extraction modes, and a succession of test, finally works out a kind of method from Asterias amurensis Lutken extracting substance of the present invention.
Summary of the invention
Main purpose of the present invention, be to provide a kind of method from Asterias amurensis Lutken extracting substance, successfully can extract important composition contained in Asterias amurensis Lutken, and this Asterias amurensis Lutken extract have multiple maintenance effect, be easy to be less readily available for absorption by the skin, really can reach the effect of moisturizing, whitening, aging resistance, anti-inflammatory etc.
In order to reach object of the present invention, the present inventor has invented a kind of method from Asterias amurensis Lutken extracting substance, comprising: (S01) obtains Asterias amurensis Lutken live body; (S02) this Asterias amurensis Lutken live body is carried out freezing, form Asterias amurensis Lutken Frozen Body; (S03) grind this Asterias amurensis Lutken Frozen Body, obtain Asterias amurensis Lutken abrasive material; (S04) this Asterias amurensis Lutken abrasive material is soaked in water, continues to heat and stirs, and is heated to more than 90 degree at least Celsius, and keeps more than at least 3 hours; (S05) undertaken filtering by drainage screen or centrifugal, after filtration, obtain the first Asterias amurensis Lutken filtrate; (S06) this first Asterias amurensis Lutken filtrate mixes with ethanol; (S07) undertaken filtering by drainage screen or centrifugal, on this drainage screen, obtain the second Asterias amurensis Lutken filtrate; (S08) this second Asterias amurensis Lutken filtrate is dissolved in the water; And (S09) this second Asterias amurensis Lutken filtrate is undertaken filtering by drainage screen or centrifugal, and get filtrate as Asterias amurensis Lutken extract.In the present invention, described Asterias amurensis Lutken live body can be style of calligraphy characterized by hollow strokes maple Asterias amurensis Lutken (Archaster typicus).
Continue above-mentioned, in step (S02), after obtaining Asterias amurensis Lutken live body, need immediately Asterias amurensis Lutken live body to be delivered to temperature in one hour freezing to carry out lower than the freezer of minus 20 degrees Celsius.In step (S03), after the grinding of this Asterias amurensis Lutken live body, obtain Asterias amurensis Lutken abrasive material by 30 to 100 meshes (mesh), then do not continue grinding by the Asterias amurensis Lutken live body of 30 to 100 meshes (mesh).In step (S04), the quality-percent by volume ratio of this Asterias amurensis Lutken abrasive material and water is 1:5 to 1:10 (w/v); The present inventor provide one can the way of reference, water can be allowed to evaporate owing to continuing to heat, in order to avoid the quantity not sufficient of water, can suitably supplementing water at any time, keep this Asterias amurensis Lutken abrasive material with the ratio of water.In step (S05), step (S07) and step (S09), the scope of this drainage screen is between 300 to 800 meshes.In step (S06), the volume-percent by volume ratio of this first Asterias amurensis Lutken filtrate and ethanol is 1:1 to 1:3.In step (S06), soak time was at 16 to 20 hours, and immersion environment maintains between Celsius temperature 4 degree to 10 degree.In step (S08), the quality-percent by volume ratio of (original text of Taiwan application case describes like this) this second Asterias amurensis Lutken filtrate and water is 1:10.In step (S09), this Asterias amurensis Lutken extract at least comprises following composition: polysaccharide (polysaccharides), ceramide (ceramides), amino acid (amino acids) and mineral trace element (trace minerals).
Accompanying drawing explanation
Fig. 1 is a kind of flow chart from Asterias amurensis Lutken extracting substance of the present invention.
Fig. 2 is the bar graph that Asterias amurensis Lutken extract of the present invention carries out uvioresistant result of the test.
Fig. 3 is the scattergram that Asterias amurensis Lutken extract of the present invention carries out reducing Oxidation result of the test.
Fig. 4 is the bar graph that Asterias amurensis Lutken extract of the present invention carries out collagen secretion result of the test.
Symbol description:
Step (S01) to step (S09) is a kind of method step from Asterias amurensis Lutken extracting substance of the present invention
Detailed description of the invention
In order to a kind of method from Asterias amurensis Lutken extracting substance proposed by the invention more clearly can be described, below cooperation is illustrated, elaborate preferred embodiment of the present invention.
First, please refer to the 1st figure, is a kind of flow chart from Asterias amurensis Lutken extracting substance of the present invention.As shown in Figure 1, the present invention is a kind of method from Asterias amurensis Lutken extracting substance, comprises the following steps: that (S01) obtains Asterias amurensis Lutken live body; (S02) this Asterias amurensis Lutken live body is carried out freezing, form Asterias amurensis Lutken Frozen Body; (S03) grind this Asterias amurensis Lutken Frozen Body, obtain Asterias amurensis Lutken abrasive material; (S04) this Asterias amurensis Lutken abrasive material is soaked in water, continues to heat and stirs, and is heated to more than 90 degree at least Celsius, and keeps more than at least 3 hours; (S05) filtered by drainage screen, filter out unwanted composition, after filtration, obtain the first Asterias amurensis Lutken filtrate; (S06) this first Asterias amurensis Lutken filtrate mixes with ethanol; (S07) filtered by drainage screen, on this drainage screen, obtain the second Asterias amurensis Lutken filtrate; (S08) this second Asterias amurensis Lutken filtrate is dissolved in the water; And (S09) this second Asterias amurensis Lutken filtrate is filtered by drainage screen, and get filtrate as Asterias amurensis Lutken extract.In the present invention, described Asterias amurensis Lutken live body can be style of calligraphy characterized by hollow strokes maple Asterias amurensis Lutken (Archaster typicus).
Continue above-mentioned, in step (S02), after obtaining Asterias amurensis Lutken live body, need immediately Asterias amurensis Lutken live body to be delivered to temperature in one hour freezing to carry out lower than the freezer of minus 20 degrees Celsius.In step (S03), after the grinding of this Asterias amurensis Lutken live body, obtain Asterias amurensis Lutken abrasive material by 30 to 100 meshes (mesh), then do not continue grinding by the Asterias amurensis Lutken live body of 30 to 100 meshes (mesh).In step (S04), the quality-percent by volume ratio of this Asterias amurensis Lutken abrasive material and water is 1:5 to 1:10 (w/v); Here can reference, water can be allowed to evaporate, in order to avoid the quantity not sufficient of water owing to continuing to heat, can suitably supplementing water at any time, keep this Asterias amurensis Lutken abrasive material with the ratio of water, should be noted that when adding water, temperature must maintain more than 90 degree Celsius, otherwise warm-up time will more than 3 hours.In step (S05), step (S07) and step (S09), the scope of this drainage screen is between 300 to 800 meshes.In step (S06), the volume-percent by volume ratio of this first Asterias amurensis Lutken filtrate and ethanol is 1:1 to 1:3.In step (S06), soak time was at 16 to 20 hours, and immersion environment maintains between Celsius temperature 4 degree to 10 degree.In step (S07), by filtration or centrifugal, collect the second Asterias amurensis Lutken filtrate on filter screen, the second Asterias amurensis Lutken filtrate of herein collecting is the curable type body through alcohol precipitation, and this second Asterias amurensis Lutken filtrate is that Asterias amurensis Lutken polysaccharide slightly extracts, and can place dry formation Asterias amurensis Lutken extraction powder, also step (S08) can be utilized, duck in drink and become Asterias amurensis Lutken extract, in step (S08), the quality-percent by volume ratio of this second Asterias amurensis Lutken filtrate and water is 1:10.In step (S09), this Asterias amurensis Lutken extract at least comprises following composition: polysaccharide (polysaccharides), ceramide (ceramides), amino acid (amino acids) and mineral trace element (trace minerals).
In the present invention, in order to avoid Asterias amurensis Lutken living body freezing is incomplete, the temperature of freezer need remain on less than 20 degree Celsius, and keeps gas circulation in this freezer, guarantees that the temperature of each position of freezer is identical.Inventor finds in process of the test, the particle size of Asterias amurensis Lutken abrasive material can affect the effect of extracting of subsequent step, when particularly filtering, particle size is by the Expected Results of impact extraction, therefore, in step (S03), select 30 to 100 meshes (mesh) as dimensional standard.In step (S05), step (S07) and step (S09), use thinner mesh to filter, the material of particularly extraction required for the present invention, particle size within the specific limits, therefore, the object of filtration is reached compared with fine mesh side.In step (S06), first load this first Asterias amurensis Lutken filtrate into container, then topple over ethanol and enter container, allow this first Asterias amurensis Lutken filtrate mix completely with ethanol, then, container is placed in freezer, this freezer maintains Celsius temperature 4 degree to 10 degree; Step (S06) mainly utilizes gravity and being separated of reaching for a long time, through under the environment of low temperature, allows ethanol be precipitated by effective ingredient, to achieve the desired result.After step (S06), once filter or centrifuging and taking precipitate, the object of this step, for obtaining more extract, collects the second Asterias amurensis Lutken filtrate through alcohol precipitation again, now, the second Asterias amurensis Lutken filtrate is very close to the composition of last Asterias amurensis Lutken extract.Step (S08) is rehydration back dissolving, and then again filter or centrifugal after get supernatant, the object of this step, for getting rid of unwanted composition, just can obtain Asterias amurensis Lutken extract of the present invention.
Except using drainage screen, in step (S05), step (S07) and step (S09), also filter centrifugal can be used, this filter centrifugal is when operating beginning, rotating speed not yet reaches more than 4000rpm, by the time the rotating speed of this filter centrifugal at least will maintain more than 10 minutes after entering the scope of 4600rpm to 4000rpm, more slowly stops, and can successfully filter.
By extracting process of the present invention, the Asterias amurensis Lutken extract obtained at least comprises following composition: polysaccharide (polysaccharides), ceramide (ceramides), amino acid (amino acids) and mineral trace element (trace minerals), wherein, the content range of polysaccharide is between 0.7 % by weight to 2 % by weight.
Asterias amurensis Lutken extract of the present invention is easy to be absorbed by the skin, and can reach effects such as promoting collagen protein generation, anti-inflammatory and scavenging free radicals fast, therefore have the effect of moisturizing, whitening, aging resistance, anti-inflammatory etc.Asterias amurensis Lutken extract contains mineral trace element, and wherein, for skin, ferrum element can be cell and provides oxygen, promotes Cellular respiration; Magnesium elements can increase skin gloss; Element silicon can promote cell regeneration; Manganese element has antioxidative function; Calcium constituent can protect skin histology; Zinc element can remove unnecessary moisture and oils and fats, improves red and swollen.From the above, mineral nitrogen mineral element can strengthen the metabolic function of skin and the anaphylaxis of skin of releiving, and makes the water profit state that skin keeps good.
In order to prove that the Asterias amurensis Lutken extract that the present invention extracts has its effect, inventor carries out following test:
(1) uvioresistant test: please refer to the 2nd figure, for Asterias amurensis Lutken extract of the present invention carries out the bar graph of uvioresistant result of the test.The energy that uvioresistant of the present invention tests the ultraviolet light used is 1.25J/cm2, and wavelength is 312 how rice, and test environment temperature is 37 degree Celsius; Test cell is ARPE cell strain, each test group has 2x104 test cell, be divided into the 1st group, the 2nd group, the 3rd group and matched group four groups, wherein, the 1st group is not added Asterias amurensis Lutken extract of the present invention, the Asterias amurensis Lutken extract of the 2nd group of interpolation 2.5%, the Asterias amurensis Lutken extract of the 3rd group of interpolation 5%, after interpolation, through 24 hours, just test; During test, ultraviolet light direct is connected on exposure experiment cell above each test group, and irradiation time is one hour; Matched group is irradiating ultraviolet light not; As shown in Figure 2, the cell survival rate of the 1st group only has 68.09% to result of the test, the cell survival rate 84.4% of the 2nd group, the cell survival rate of the 3rd group then reaches 97.23%, it can thus be appreciated that, add the Asterias amurensis Lutken extract of 5%, the survival rate of cell under UV environment can be increased.Therefore, if Asterias amurensis Lutken extract of the present invention is applied to skin, allows Skin Cell absorb Asterias amurensis Lutken extract of the present invention, then can increase the survival rate of Skin Cell under UV environment.
(2) Oxidation test is reduced: please refer to the 3rd figure, for Asterias amurensis Lutken extract of the present invention carries out the scattergram reducing Oxidation result of the test.Before the present invention reduces Oxidation test, need and prepare in advance, first, by the Asterias amurensis Lutken extract of the present invention of 0.5mL, under 50 degree Celsius, mix 20 minutes with phosphate-buffered salt (phosphate) and the potassium ferricyanide (potassium ferricyanide) solution, wherein, phosphate-buffered salt (phosphate) is 0.2 mole, pH value is 6.6, and potassium ferricyanide solution is 0.5mL; Then, add 0.5mL water, wherein, this 0.5mL water contains the trichloroacetic acid (trichloroacetic acid) of 1%, and then carry out centrifugal operation, this centrifugal operation carries out 10 minutes at less than 20 degree Celsius, and centrifugal force is 1000g; After completing centrifugal operation, take out the supernatant of 1mL, and with the water of 1mL and the water mixing of 0.2mL, the water of this 0.2mL contains the iron chloride of 0.1%, so, just completes and has prepared in advance; Then, in the scope of 25 degree to 28 degree Celsius of atmospheric environment, in rayless situation, test is carried out ten minutes.Experimental result as shown in Figure 3, for hydrolysis Asterias amurensis Lutken extract, has carried out the test of different content, from figure, along with the content of hydrolysis Asterias amurensis Lutken extract increases, vitamin C equivalent also and then increases, it can thus be appreciated that Asterias amurensis Lutken extract of the present invention has the effect reducing Oxidation.
(3) collagen secretion test: please refer to the 4th figure, for Asterias amurensis Lutken extract of the present invention carries out the bar graph of collagen secretion result of the test.Test cell is the fibroblast of human body skin, CCD-966SK cell strain, be placed in the culture dish in 24 holes, 37 degree Celsius of ambient temperature, carbon dioxide content 5%, each hole culture dish has the cell density of 4*104, and comprises the culture fluid of 10%, wherein, this culture fluid is that serum is as hyclone (fetal bovine serum; FBS); Through 24 as a child, culture fluid was changed; Altogether after 48 hours, namely supernatant is precipitated.Then, the supernatant of 100 μ L at room temperature mixes 30 minutes with stain, and then, carry out the centrifugal operation of 10 minutes, wherein, the centrifugal force of this centrifugal operation is 15000g, finally, measures the secretory volume of collagen protein.This experiment has two groups, an experimental group, a matched group, and experimental group has interpolation Asterias amurensis Lutken extract of the present invention, and matched group does not then add.Can see from the 4th figure, compared to matched group, the collagen secretion amount of experimental group is obviously high, it can thus be appreciated that Asterias amurensis Lutken extract of the present invention can increase the secretory volume of collagen protein.
Above-mentioned experiment has illustrated effect of Asterias amurensis Lutken extract of the present invention, known by extracting process provided by the present invention, the Asterias amurensis Lutken extract extracted, that there is the effect promoting skin cell metabolism, therefore, not only may be used for skin of face, be more suitable for the maintenance of parts of body skin and hair, scalp.
Asterias amurensis Lutken extract of the present invention is when preserving, sealing effectiveness must be noted more, affect with the reaction intercepting external environment and Asterias amurensis Lutken extract, the environmental factorss such as such as air, dampness, light or heat, to avoid Asterias amurensis Lutken extract polluted and be oxidized, that improves Asterias amurensis Lutken extract utilizes effect, improves quality, safety, really validity, the absorbability of application and skin can be improved, helped active substance to play complete maintenance function.
In addition, Asterias amurensis Lutken extract of the present invention can with following composition mixing, to increase whitening, or the effect of skin metabolism, similarly be kojic acid (Kojic Acid), Folium Vaccinii vitis-idaeae foline (Arbutin), vitamin C sodium phosphate (Sodium Ascorbyl Phosphate), Magnesium Ascorbyl Phosphate (Magnesium Ascorbyl Phosphate).And this kojic acid, Folium Vaccinii vitis-idaeae foline, vitamin C sodium phosphate, Magnesium Ascorbyl Phosphate etc.
Asterias amurensis Lutken extract of the present invention, can have multiple different application.Such as, make essence, essential oils, elite breast, essence cream or facial film etc. further, improve the selectivity of consumption group, obtain effect of Asterias amurensis Lutken extract by different way.In addition, also can add containing microgranule facial film, cleansing milk etc., make for facial, clean product, even add shampoo, hair care breast etc., make the product being used in hair.Asterias amurensis Lutken extract of the present invention can effectively utilize the bioactive substance and trace element that are rich in Asterias amurensis Lutken extract in skin care, particularly after being dissolved in solvent, the active skull cap components of its high activity Asterias amurensis Lutken extract directly can be absorbed by skin, increases the usefulness of absorption of human body.It is noted that, the Asterias amurensis Lutken extract that extracting process of the present invention extracts, there is this effect side, and different extraction modes can cause last extract composition variant, and then affects effect.
After above-mentioned detailed description, have a clear understanding of technical characteristic of the present invention, Asterias amurensis Lutken extracting process provided by the present invention, successfully can extract important composition contained in Asterias amurensis Lutken, and this Asterias amurensis Lutken extract has multiple maintenance effect, be easy to be less readily available for absorption by the skin, really can reach the effect of moisturizing, whitening, aging resistance, anti-inflammatory etc.
Above-mentioned detailed description is illustrating for possible embodiments of the present invention, only this embodiment be not used to limit the scope of the claims of the present invention, and the equivalence that all the present invention's of disengaging spirit is done is implemented or changes, and all should be contained in the scope of the claims of this case.
Claims (10)
1. from a method for Asterias amurensis Lutken extracting substance, it is characterized in that, comprise the following steps:
(S01) Asterias amurensis Lutken live body is obtained;
(S02) this Asterias amurensis Lutken live body is carried out freezing, form Asterias amurensis Lutken Frozen Body;
(S03) grind this Asterias amurensis Lutken Frozen Body, obtain Asterias amurensis Lutken abrasive material;
(S04) this Asterias amurensis Lutken abrasive material is soaked in water, continues to heat and stirs, and is heated to more than 90 degree at least Celsius, and keeps more than at least 3 hours;
(S05) filtered by a drainage screen, after filtration, obtain the first Asterias amurensis Lutken filtrate;
(S06) this first Asterias amurensis Lutken filtrate mixes with ethanol;
(S07) filtered by a drainage screen, on this drainage screen, obtain the second Asterias amurensis Lutken filtrate;
(S08) this second Asterias amurensis Lutken filtrate is dissolved in the water; And
(S09) this second Asterias amurensis Lutken filtrate is filtered by drainage screen, gets filtrate and obtain Asterias amurensis Lutken extract after filtration.
2., as claimed in claim 1 from the method for Asterias amurensis Lutken extracting substance, it is characterized in that, in step (S02), after obtaining Asterias amurensis Lutken live body, in one hour, Asterias amurensis Lutken live body is delivered to temperature freezing to carry out lower than the freezer of minus 20 degrees Celsius.
3. as claimed in claim 1 from the method for Asterias amurensis Lutken extracting substance, it is characterized in that, in step (S03), after the grinding of this Asterias amurensis Lutken live body, obtain Asterias amurensis Lutken abrasive material by 30 to 100 meshes, then do not continue grinding by the Asterias amurensis Lutken live body of 30 to 100 meshes.
4., as claimed in claim 1 from the method for Asterias amurensis Lutken extracting substance, it is characterized in that, in step (S04), the quality-percent by volume ratio of this Asterias amurensis Lutken abrasive material and water is 1:5 to 1:10.
5., as claimed in claim 1 from the method for Asterias amurensis Lutken extracting substance, it is characterized in that, in step (S05), step (S07) and step (S09), the scope of this drainage screen is between 300 to 800 meshes.
6., as claimed in claim 1 from the method for Asterias amurensis Lutken extracting substance, it is characterized in that, in step (S06), the volume-percent by volume ratio of this first Asterias amurensis Lutken filtrate and ethanol is 1:1 to 1:3.
7. as claimed in claim 6 from the method for Asterias amurensis Lutken extracting substance, it is characterized in that, in step (S06), soak time was at 16 to 20 hours, and immersion environment maintains between Celsius temperature 4 degree to 10 degree.
8., as claimed in claim 1 from the method for Asterias amurensis Lutken extracting substance, it is characterized in that, in step (S08), the quality-percent by volume ratio of this second Asterias amurensis Lutken filtrate and water is 1:10.
9. as claimed in claim 1 from the method for Asterias amurensis Lutken extracting substance, it is characterized in that, in step (S09), this Asterias amurensis Lutken extract at least comprises following composition: polysaccharide, ceramide, amino acid and mineral trace element, wherein, the content range of polysaccharide is between 0.7 % by weight to 2 % by weight.
10., as claimed in claim 1 from the method for Asterias amurensis Lutken extracting substance, it is characterized in that, described Asterias amurensis Lutken live body is style of calligraphy characterized by hollow strokes maple Asterias amurensis Lutken.
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| TW102141620 | 2013-11-15 | ||
| TW102141620A TW201517931A (en) | 2013-11-15 | 2013-11-15 | A method for extracting substance from starfish |
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Cited By (3)
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| CN106070336A (en) * | 2016-06-19 | 2016-11-09 | 青岛科光生物技术有限公司 | The manufacture method of Asterias amurensis Lutken extracting solution |
| CN109966196A (en) * | 2019-03-01 | 2019-07-05 | 王珊珊 | A kind of natural Essence and preparation method thereof with healing |
| CN110025555A (en) * | 2019-03-28 | 2019-07-19 | 广州市茗妍化妆品有限公司 | A kind of repair cream and preparation method thereof |
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| CN101804075A (en) * | 2010-04-23 | 2010-08-18 | 大连美罗中药厂有限公司 | Application of starfishes to preparation of medicament for treating osteoporosis |
| TWM458987U (en) * | 2013-02-19 | 2013-08-11 | Tci Co Ltd | Starfish extract particulate structure for promoting skin cell metabolism and regrowth |
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| KR20100054273A (en) * | 2008-11-14 | 2010-05-25 | 부경대학교 산학협력단 | A preventive and theraputic composition comprising of polysaccharides from starfish |
| CN101804075A (en) * | 2010-04-23 | 2010-08-18 | 大连美罗中药厂有限公司 | Application of starfishes to preparation of medicament for treating osteoporosis |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106070336A (en) * | 2016-06-19 | 2016-11-09 | 青岛科光生物技术有限公司 | The manufacture method of Asterias amurensis Lutken extracting solution |
| CN109966196A (en) * | 2019-03-01 | 2019-07-05 | 王珊珊 | A kind of natural Essence and preparation method thereof with healing |
| CN110025555A (en) * | 2019-03-28 | 2019-07-19 | 广州市茗妍化妆品有限公司 | A kind of repair cream and preparation method thereof |
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| TW201517931A (en) | 2015-05-16 |
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