CN104628163B - A kind of composition and application thereof for disinfecting corrosion inhibitor - Google Patents
A kind of composition and application thereof for disinfecting corrosion inhibitor Download PDFInfo
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- CN104628163B CN104628163B CN201310556765.9A CN201310556765A CN104628163B CN 104628163 B CN104628163 B CN 104628163B CN 201310556765 A CN201310556765 A CN 201310556765A CN 104628163 B CN104628163 B CN 104628163B
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Abstract
The invention discloses a kind of disinfecting corrosion inhibitor composition, this disinfecting corrosion inhibitor contains antibiotic and stannous salt with composition, and described antibiotic is selected from least two kinds in macrolide antibiotics, TCs, beta-lactam antibiotic and aminoglycoside antibiotics. The invention also discloses the application of above-mentioned disinfecting corrosion inhibitor composition in circulating cooling water treatment. By technique scheme, when disinfecting corrosion inhibitor of the present invention is used for to recirculating cooling water system with composition, can obtain preferably sterilization and corrosion mitigating effect simultaneously.
Description
Technical field
The present invention relates to a kind of disinfecting corrosion inhibitor composition and application thereof, particularly, relate to a kind of sterilizationComposition and the application in circulating cooling water treatment thereof for corrosion inhibiter.
Background technology
The operation maintenance of industrial circulating cooling water system relates to and solves three of fouling, corrosion and control of microorganismsThe problem of aspect. For solving this three problems, generally adopt cost-effective method be add antisludging agent,Corrosion inhibiter and bactericide. Bactericide is divided into oxidizing bactericide and non oxidizing bactericide. Conventional oxidationProperty bactericide has strong chlorine oil, Babysafe, organic bromine etc.; Conventional non oxidizing bactericide have quaternary ammonium salt,OIT, glutaraldehyde etc. In water treatment, employing alternately adds oxidizing bactericide and non-conventionallyThe method of oxidizing bactericide is carried out the micro organism quantity in controlled circulation cooling water. Although chlorine series bactericidal agent winkTime bactericidal effect well but the sterilization duration short, and be there is to certain corrosivity in carbon steel equipment. SeasonAmmonium salt class easily produces drug resistance, and in the last few years, a lot of people were carrying out modification to quaternary ammonium salt, or seekZhao quaternary alkylphosphonium salt replaces quaternary ammonium salt, but not too large lifting of bactericidal effect.
CN1789159A discloses a kind of disinfecting corrosion inhibitor, and this disinfecting corrosion inhibitor comprises bactericide, surfaceActivating agent, corrosion inhibiter, solvent and organic phosphate, form through being uniformly mixed. Described disinfecting corrosion inhibitor existsIn the recirculating cooling water system of copper material, can play that sterilization algae removal, foundry loam are peeled off, pre-film texts. ShouldIt is narrow that invention limits the strict scope of application to equipment material, is mainly applicable to the circulating cooling water system of copper materialSystem.
CN1418830A discloses a kind of both sexes disinfecting corrosion inhibitor, and this both sexes disinfecting corrosion inhibitor is by alkyl quaternaryAmine inner salt, quaternary ammonium halide, non-ionic surface active agent, solvent and water composition. Though this disinfecting corrosion inhibitorFor both sexes disinfecting corrosion inhibitor, but corrosion mitigating effect is not good, and when working concentration is 40mg/L, corrosion inhibition rate only has69%。
Antibiotic is to be lived by microorganism (comprising bacterium, fungi and actinomyces) or high animals and plantsThe class secondary metabolite with antipathogen or other activity producing in journey, can disturb other rawLiving cells is grown the chemical substance of function. Antibiotic antibacterial or bactericidal action mechanism mainly contains 4 kinds: press downThe permeability, the interference albumen that synthesize, change with cell membrane interaction cell membrane of bacteria cell wall processedSynthesizing of matter and transcribing and copying of inhibition nucleic acid. Antibiotic is mainly for " bacterium has and people or otherHigher mammal does not have " mechanism play a role, therefore antibiotic is multiplex with it people and animal. At present alsoThere is the farm antibiotics for crops. But do not see antibiotic for recirculating cooling water systemReport.
Summary of the invention
The object of the invention is to overcome and in prior art, be difficult to obtain sterilization and corrosion mitigating effect all kills preferablyThe defect of bacterium corrosion inhibiter, provide a kind of sterilization and corrosion mitigating effect all preferably disinfecting corrosion inhibitor composition andIts application.
To achieve these goals, the present inventor has carried out a large amount of experiments, found that, willAntibiotic and stannous salt cooperation not only have preferably bactericidal effect as disinfecting corrosion inhibitor, also haveGood corrosion inhibition. Therefore, the invention provides a kind of disinfecting corrosion inhibitor composition, wherein, this killsBacterium corrosion inhibiter contains antibiotic and stannous salt with composition, and described antibiotic is selected from macrolides antibiosisIn element, TCs, beta-lactam antibiotic and aminoglycoside antibiotics at least two kinds.
The present invention also provides the application of above-mentioned disinfecting corrosion inhibitor composition in circulating cooling water treatment.
By technique scheme, disinfecting corrosion inhibitor of the present invention is used for to circulating cooling water system with compositionIn system time, can obtain preferably sterilization and corrosion mitigating effect simultaneously.
Other features and advantages of the present invention are described in detail the detailed description of the invention part subsequently.
Detailed description of the invention
Below the specific embodiment of the present invention is elaborated. Should be understood that, retouch in this placeThe detailed description of the invention of stating only, for description and interpretation the present invention, is not limited to the present invention.
Disinfecting corrosion inhibitor provided by the invention contains antibiotic and stannous salt with composition, described antibioticBe selected from macrolide antibiotics, TCs, beta-lactam antibiotic and aminoglycosideIn antibiotic at least two kinds.
According to the present invention, as long as antibiotic and stannous salt are coordinated as disinfecting corrosion inhibitor compositionActive component can be realized object of the present invention, and the content of antibiotic and stannous salt is not wanted especiallyAsk, for example, taking described disinfecting corrosion inhibitor by the total amount of composition as benchmark, antibiotic and stannous saltContent sum can change within the scope of 5-100 % by weight, under preferable case, with described disinfecting corrosion inhibitorWith the total amount of composition be benchmark, the content sum of antibiotic and stannous salt is 8-95 % by weight.
According to the present invention, as long as antibiotic and stannous salt are used in conjunction with and can realize order of the present invention, the weight ratio of described antibiotic and stannous salt is not particularly limited, but preferably, described antibiosisElement is 0.3-7:1, more preferably 0.8-2.5:1 with the weight ratio of stannous salt.
In the present invention, macrolide antibiotics refers to and in molecular structure, contains a parent nucleus---in large ringThe antibiotic of ester. The present invention does not have special requirement to the kind of described macrolide antibiotics, canFor the macrolide antibiotics of various routines, and all can be by commercially available. Under preferable case, instituteState macrolide antibiotics and be selected from erythromycin, albomycin, acetyl spiramycin, medecamycin and Jiao ShaAt least one in mycin.
TCs refers to a class antibiotic in molecular structure with aphthacene structure. The present inventionThe kind of described TCs is not had to special requirement, can be the Tetracyclines of various routinesAntibiotic, and all can be by commercially available. Under preferable case, described TCs is selected from fourAt least one in ring element, terramycin, aureomycin, Doxycycline, Klinomycin and metacycline.
Beta-lactam antibiotic refers to the antibiotic in molecular structure with beta-lactam nucleus. The present invention coupleThe kind of described beta-lactam antibiotic does not have special requirement, can be the beta-lactam of various routinesClass antibiotic (comprising clinical the most frequently used PCs and cephalosporins etc.), andAll can be by commercially available. Under preferable case, described beta-lactam antibiotic is that cephalosporins is anti-Raw element (can be first generation cephalosporin, second generation cephalosporin, third generation cephalosporin and the 4th generationOne or more in cynnematin). More preferably, described beta-lactam antibiotic is selected from cephalo azolesQuinoline sodium, cefalexin, Cefradine, cefadroxil, Cefaclor, Cefamandole Nafate, cephaloWestern fourth sodium, cefuroxime, cefoperazone sodium, Cefotaxime Sodium, cefotaxime, ceftizoxime sodium and peaceAt least one of Qu Nanzhong.
Aminoglycoside antibiotics refers in molecule and contains a cyclohexanol aglucon, with glycosidic bond and amino sugarThe compounds that (or neutral sugar) combines. The kind of the present invention to described aminoglycoside antibioticsThere is no special requirement, can (comprise clinical the most frequently used for the aminoglycoside antibiotics of various routinesStreptidine derivative class, inositol-inosamine derivative class and 2-deoxystreptamine derivative class etc.), and allCan be by commercially available. Under preferable case, described aminoglycoside antibiotics is selected from streptomysin, celebrating is largeMycin, kanamycins, TOB, amikacin, neomycin, ribostamycin, micronomicinWith at least one in A Si mycin.
According to the present invention, as long as at least two kinds in above antibiotic are used in conjunction with stannous saltRealize object of the present invention, all kinds of antibiotic consumptions are had no particular limits, can be identical or different.
In the present invention, described stannous salt can be the common various stannous salts in this area, is preferably halogenChange sub-tin, further, under preferable case, described stannous salt is stannous chloride and/or stannous bromide.
According to the present invention, in order further to strengthen the sterilization inhibition of disinfecting corrosion inhibitor of the present invention compositionEffect, described disinfecting corrosion inhibitor can also further contain non oxidizing bactericide with composition, described non-Oxidizing bactericide is selected from quaternary ammonium salt type bactericidal agent, phosphonium salt bactericidal agent and OIT at leastA kind of. In the time that disinfecting corrosion inhibitor of the present invention contains non oxidizing bactericide with composition, at antibiotic andIn the situation of the content sum lower (as following in 70 % by weight) of stannous salt, also can obtain preferablySterilization corrosion mitigating effect. Wherein, commercially available various quaternary ammonium salt type bactericidal agent, phosphonium salt bactericidal agents and different thiopheneAzoles quinoline ketone all can be used for the present invention.
Described quaternary ammonium salt type bactericidal agent can be single long chain quaternary. Described single long chain quaternary is preferably selected fromGeneral formula is R1(R3)2NR2The quaternary ammonium salt of X, wherein R1For the chain alkyl that carbon number is 8-20, excellentElect dodecyl, myristyl, cetyl or octadecyl as; R2For aryl or aralkyl, preferablyFor the carbon number aralkyl that is 7-11; R3For the alkyl that carbon number is 1-4, be preferably methyl; XFor chlorine or bromine.
Described phosphonium salt bactericidal agent can be single long chain quaternary alkylphosphonium salt. Described Dan Changlian quaternary alkylphosphonium salt is preferably selected fromGeneral formula is R4(R5)3PX quaternary alkylphosphonium salt, wherein R4For the chain alkyl that carbon number is 8-20, preferredFor dodecyl, myristyl or cetyl; R5For the alkyl that carbon number is 1-4, be preferably fourthBase; X is chlorine or bromine.
For example, described quaternary ammonium salt type bactericidal agent can be dodecyl benzyl dimethyl ammonium chloride, dodecaneBase dimethyl benzyl ammonium bromide, myristyl dimethyl benzyl ammonium chloride, hexadecyldimethyl benzyl ammonium benzyl chlorideChange at least one in ammonium and octadecyl dimethyl benzyl ammonium bromide. Described phosphonium salt bactericidal agent is passableFor dodecyl tributyl phosphonium chloride, myristyl tributyl phosphonium chloride, phosphonium hexadecanyl-3-butyl chlorideWith at least one in hexadecyl tributyl phosphonium bromide. Described OIT is a class broad-spectrum high efficacyIndustry biocide mildewcide, can be by commercially available, and the active ingredient of described OIT is the chloro-2-of 5-Methyl-4-isothiazoline-3-ketone and MIT, and the weight ratio of the two conventionally canFor 2-5:1, be preferably 3:1, but be not limited to this.
According to the present invention, the content of described non oxidizing bactericide is had no particular limits, can be thisThe conventional amount used in field, preferably, the weight ratio of described non oxidizing bactericide and stannous salt is0.2-60:1, more preferably 1-30:1.
Further preferably, described non oxidizing bactericide is quaternary ammonium salt type bactericidal agent, described quaternaryThe weight ratio of bactericide and stannous salt is 5-40:1, most preferably is 10-25:1; Or
Described non oxidizing bactericide is phosphonium salt bactericidal agent, described phosphonium salt bactericidal agent and Bivalent TinThe weight ratio of salt is 5-25:1, most preferably is 10-15:1; Or
Described non oxidizing bactericide is OIT, the weight of described OIT and stannous saltThan for 0.2-3:1, most preferably be 0.5-1.5:1.
The present inventor finds, adopts sterilization inhibition of the present invention according to mentioned kind and content proportioningWhen agent is carried out circulating cooling water treatment with composition, can obtain better sterilization corrosion inhibition.
The present invention also provides the application of above-mentioned disinfecting corrosion inhibitor composition in circulating cooling water treatment.
According to the present invention, it is cold that described disinfecting corrosion inhibitor is preferably 1-20mg/L circulation with the consumption of compositionBut water, more preferably 1.5-14mg/L recirculated cooling water.
Disinfecting corrosion inhibitor of the present invention is applicable to the various disinfecting corrosion inhibitors that need routinely to add with compositionRecirculated cooling water, still, the present inventor find, disinfecting corrosion inhibitor composition of the present inventionBe particularly useful for the recirculated cooling water that pH value is 7-10, therefore, preferably, described recirculated cooling waterPH value is 7-10.
According to disinfecting corrosion inhibitor composition of the present invention, in the time that reality is used, as long as by antibiotic and twoValency pink salt can be realized object of the present invention for recirculated cooling water ordinatedly, each raw material can be mixedAfter add again in recirculated cooling water, also each raw material directly can be added to recirculated water without blend stepIn, and can add, also can add successively. simultaneously
Below will describe the present invention by embodiment. In following examples, " use in testIn water, add * mg/LA material " mean in test water, to add A material, and add A after A materialThe concentration of material in test water is * mg/L test water; The antibiotic using is all purchased from Beijing the Temple of HeavenPharmaceutical Biotechnology development company; OIT (the CMIT usingWith the two mixture of MIT, the two weight ratio is 3:1, and effective content is 1.6%)Purchased from Beijing Tianqing Chemical Co., Ltd.; The water quality of test water 1 is: Ca2+(with CaCO3Meter) containAmount is 229.4mg/L, and basicity is (with CaCO3Meter) be 232.1mg/L, pH value is 7.5; Test is usedThe water quality of water 2 is: Ca2+(with CaCO3Meter) content is 97mg/L, basicity is (with CaCO3Meter)For 157mg/L, pH value is 7.8; The assay method of each parameter is as follows:
Ca2+: reference standard GB/T6910-2006;
Basicity: reference standard GB/T15451-2006;
PH value: reference standard GB/T6920-1986.
The assay method of corrosion rate is: the test piece of 20# quality carbon steel is fixed on lacing film instrument, put into byEach embodiment and comparative example have added in the test water of medicament, and steady temperature is 45 ± 1 DEG C, keep rotating speed75rpm rotates 72h, and before and after record test, the weight of test piece, calculates corrosion rate. Corrosion rate definitionFor the inhibition efficiency of corrosion inhibiting and descaling agent.
The computing formula of corrosion rate (F) is: F=(C × △ W)/(A × T × ρ), wherein,
C: computational constant, taking mm/a(millimeter/year) during as unit, C=8.76 × 107
△ W: the corrosion weight loss (g) of test specimen
A: the area (cm of test specimen2）
T: corrosion test time (h)
ρ: the density (kg/m of material for test3）
Bactericidal property evaluation method is as follows: medicament is added in test water and (need to regulate the use of pH valueThe sodium hydroxide solution of 2 % by weight is adjusted to specifies numerical value), respectively add the 1h of medicament, 4h, 8h,24h, 48h and 72h sampling are done heterotroph number and are measured, and the initial heterotroph number of test water is 1.5 × 106Individual/ml. It is as follows that heterotroph is counted assay method: get the test water that is added with medicament, in desinfection chamber, adopt10 times of dilution technologies of former water, are diluted to suitable multiple by test water, and by corresponding extension rateWater sample is inoculated in culture dish. Then aseptic culture medium is poured in culture dish, mixes with water sample,Cultivate 72 ± 4h etc. being inverted after culture medium solidifying to be placed in the incubator of 29 ± 1 DEG C. After cultivation, take out and cultivateWare, selects those culture dishes with 30-300 bacterium colony to count, and clump count is multiplied by corresponding rareRelease the heterotroph number that multiple is this water sample. The initial heterotroph number of test water is 1.5 × 106Individual/ml.
Embodiment 1
In test water 1, add 0.9mg/L erythromycin, 0.9mg/L brizolina, 0.8mg/LStannous chloride, by 2 % by weight NaOH adjusting pH values to 9.5, puts into the guarantor of 29 ± 1 DEG C after shaking upIn incubator, sample analysis heterotroph number in required time, and carry out the determination test of corrosion rate, resultIn table 1.
Embodiment 2
In test water 1, add 0.8mg/L albomycin, 0.8mg/L cefalexin, 0.7mg/L chlorinationYa Xi, puts into the incubator of 29 ± 1 DEG C after shaking up, sample analysis heterotroph number, goes forward side by side in required timeThe determination test of row corrosion rate, the results are shown in Table 1.
Embodiment 3
In test water 1, add 0.7mg/L acetyl spiramycin, 0.7mg/L streptomysin, 0.6mg/LStannous chloride, by 2 % by weight NaOH adjusting pH values to 8.0, puts into the guarantor of 29 ± 1 DEG C after shaking upIn incubator, sample analysis heterotroph number in required time, and carry out the determination test of corrosion rate, resultIn table 1.
Embodiment 4
In test water 1, add 0.6mg/L tetracycline, 0.6mg/L Cefradine, 0.5mg/L chlorinationYa Xi, puts into the incubator of 29 ± 1 DEG C after shaking up, sample analysis heterotroph number, goes forward side by side in required timeThe determination test of row corrosion rate, the results are shown in Table 1.
Embodiment 5
In test water 2, add 0.5mg/L terramycin, 0.5mg/L gentamicin, 0.4mg/L brominationYa Xi, puts into the incubator of 29 ± 1 DEG C after shaking up, sample analysis heterotroph number, goes forward side by side in required timeThe determination test of row corrosion rate, the results are shown in Table 1.
Embodiment 6
In test water 2, add 0.4mg/L cefadroxil, 0.4mg/L kanamycins, 0.7mg/LStannous chloride, puts into the incubator of 29 ± 1 DEG C after shaking up, sample analysis heterotroph number in required time,And carry out the determination test of corrosion rate, the results are shown in Table 1.
Embodiment 7
In test water 1, add 0.3mg/L Cefaclor, 0.3mg/L TOB, 0.6mg/LStannous chloride, puts into the incubator of 29 ± 1 DEG C after shaking up, sample analysis heterotroph number in required time,And carry out the determination test of corrosion rate, the results are shown in Table 1.
Embodiment 8
In test water 2, add 0.2mg/L medecamycin, 0.2mg/L Cefamandole Nafate, 0.5mg/LStannous chloride, 12mg/L dodecyl benzyl dimethyl ammonium chloride, puts into the insulation of 29 ± 1 DEG C after shaking upIn case, sample analysis heterotroph number in required time, and carry out the determination test of corrosion rate, the results are shown inTable 1.
Embodiment 9
In test water 2, add 0.2mg/L josamycin, 0.2mg/L cefoxitin sodium, 0.2mg/LA Si mycin, 0.4mg/L stannous chloride, 10mg/L dodecyl dimethyl benzyl ammonium bromide, after shaking upPut into the incubator of 29 ± 1 DEG C, sample analysis heterotroph number in required time, and carry out corrosion rateDetermination test, the results are shown in Table 1.
Embodiment 10
In test water 1, add 0.3mg/L metacycline, 0.3mg/L amikacin, 0.5mg/LStannous chloride, 7mg/L dodecyl tributyl phosphonium chloride, puts into the incubator of 29 ± 1 DEG C after shaking up,Sample analysis heterotroph number in required time, and carry out the determination test of corrosion rate, the results are shown in Table 1.
Embodiment 11
In test water 1, add 0.2mg/L ceftazidime, add 0.3mg/L neomycin, 0.5mg/LStannous chloride, 6mg/L myristyl tributyl phosphonium chloride, puts into the incubator of 29 ± 1 DEG C after shaking up,Sample analysis heterotroph number in required time, and carry out the determination test of corrosion rate, the results are shown in Table 1.
Embodiment 12
In test water 1, add 0.2mg/L ceftizoxime sodium, 0.4mg/L ribostamycin, 0.5mg/LStannous chloride, 0.7mg/L OIT, puts into the incubator of 29 ± 1 DEG C, in accordance with regulations time after shaking upBetween sample analysis heterotroph number, and carry out the determination test of corrosion rate, the results are shown in Table 1.
Embodiment 13
In test water 2, add 0.3mg/L peace Qu Nan, 0.3mg/L micronomicin, 0.6mg/L chlorinationYa Xi, 0.4mg/L OIT, puts into the incubator of 29 ± 1 DEG C after shaking up, get in required timeSample is analyzed heterotroph number, and carries out the determination test of corrosion rate, the results are shown in Table 1.
Embodiment 14
In test water 2, add 0.4mg/L aureomycin, 0.4mg/L cefuroxime, 0.5mg/L chlorinationYa Xi, 10mg/L myristyl dimethyl benzyl ammonium chloride, 0.5mg/L OIT, puts after shaking upEnter in the incubator of 29 ± 1 DEG C, sample analysis heterotroph number in required time, and carry out the survey of corrosion rateFixed test, the results are shown in Table 1.
Embodiment 15
In test water 1, add 0.3mg/L Doxycycline, 0.4mg/L cefoperazone sodium, 0.5mg/LStannous bromide, 6mg/L cetalkonium chloride, the chlorination of 5mg/L cetyl tributylPhosphonium, puts into the incubator of 29 ± 1 DEG C after shaking up, sample analysis heterotroph number in required time, and carry outThe determination test of corrosion rate, the results are shown in Table 1.
Embodiment 16
In test water 2, add 0.3mg/L Klinomycin, 0.3mg/L Cefotaxime Sodium, 0.6mg/LStannous chloride, 5mg/L octadecyl dimethyl benzyl ammonium bromide, 5mg/L hexadecyl tributyl phosphoniumPhosphonium, 0.3mg/L OIT, puts into the incubator of 29 ± 1 DEG C after shaking up, in required time samplingAnalyze heterotroph number, and carry out the determination test of corrosion rate, the results are shown in Table 1.
Embodiment 17
In test water 1, add 0.1mg/L erythromycin, 0.7mg/L brizolina, 1.8mg/LStannous chloride, puts into the incubator of 29 ± 1 DEG C after shaking up, sample analysis heterotroph number in required time,And carry out the determination test of corrosion rate, the results are shown in Table 1.
Embodiment 18
In test water 1, add 0.3mg/L erythromycin, 0.1mg/L brizolina, 2.2mg/LStannous chloride, puts into the incubator of 29 ± 1 DEG C after shaking up, sample analysis heterotroph number in required time,And carry out the determination test of corrosion rate, the results are shown in Table 1.
Comparative example 1
In test water, add 12.9mg/L dodecyl benzyl dimethyl ammonium chloride, after shaking up, put intoIn the incubator of 29 ± 1 DEG C, sample analysis heterotroph number in required time, and carry out the mensuration of corrosion rateTest, the results are shown in Table 1.
Comparative example 2
In test water, add 8.1mg/L dodecyl tributyl phosphonium chloride, after shaking up, put into 29 ± 1 DEG CIncubator in, sample analysis heterotroph number in required time, and carry out the determination test of corrosion rate,The results are shown in Table 1.
Comparative example 3
In test water, add 1.8mg/L OIT, after shaking up, put into the incubator of 29 ± 1 DEG CIn, sample analysis heterotroph number in required time, and carry out the determination test of corrosion rate, the results are shown in Table1。
Comparative example 4
In test water 1, add 1.3mg/L erythromycin, 1.3mg/L brizolina, puts after shaking upEnter in the incubator of 29 ± 1 DEG C, sample analysis heterotroph number in required time, and carry out the survey of corrosion rateFixed test, the results are shown in Table 1.
Comparative example 5
In test water 1, add 2.6mg/L stannous chloride, after shaking up, put into the incubator of 29 ± 1 DEG C,Sample analysis heterotroph number in required time, and carry out the determination test of corrosion rate, the results are shown in Table 1.
Comparative example 6
In test water 1, do not add any medicament, carry out the determination test of corrosion rate, the results are shown in Table1。
Table 1
Represent that from table 1("/" measured heterotroph number has exceeded starter bacteria number) result can find out,Disinfecting corrosion inhibitor of the present invention with composition aspect sterilization, have excellent bactericidal effect and sterilization continueTime is long, and meanwhile, it also shows good corrosion inhibition aspect inhibition.
Especially, embodiment 1 is compared and can be found out with the result of embodiment 17 and 18, by thisInventing preferred weight ratio is used in conjunction with antibiotic and stannous salt can to obtain more excellent sterilization slowErosion effect. Embodiment 8,10 and 12 is compared and can be found out with the result of comparative example 1-3 respectively,Non oxidizing bactericide and antibiotic and stannous salt are used in conjunction with than only using non oxidizing bactericideShow more excellent sterilization corrosion inhibition. In addition, by each embodiment (particularly embodiment 1)Compare and can find out with the result of comparative example 4 and 5, antibiotic is coordinated as killing with stannous saltBacterium corrosion inhibiter could obtain excellent sterilization corrosion mitigating effect during with the active component of composition.
More than describe the preferred embodiment of the present invention in detail, still, the present invention is not limited to above-mentioned realityExecute the detail in mode, within the scope of technical conceive of the present invention, can be to technical side of the present inventionCase is carried out multiple simple variant, and these simple variant all belong to protection scope of the present invention.
It should be noted that in addition each the concrete technology spy described in above-mentioned detailed description of the inventionLevy, in reconcilable situation, can combine by any suitable mode, for fear of needn'tThe repetition of wanting, the present invention is to the explanation no longer separately of various possible combinations.
In addition, between various embodiment of the present invention, also can be combined, as long as itsWithout prejudice to thought of the present invention, it should be considered as content disclosed in this invention equally.
Claims (15)
1. a disinfecting corrosion inhibitor composition, is characterized in that, this disinfecting corrosion inhibitor contains with compositionHave antibiotic and stannous salt, described antibiotic be selected from macrolide antibiotics, TCs,In beta-lactam antibiotic and aminoglycoside antibiotics at least two kinds, wherein, described antibiotic withThe weight ratio of stannous salt is 0.3-7:1;
Described macrolide antibiotics is selected from erythromycin, albomycin, acetyl spiramycin, medecamycinWith at least one in josamycin;
It is mould that described TCs is selected from tetracycline, terramycin, aureomycin, Doxycycline, minotAt least one in element and metacycline;
Described beta-lactam antibiotic is cephalosporins;
Described aminoglycoside antibiotics be selected from streptomysin, gentamicin, kanamycins, TOB,At least one in amikacin, neomycin, ribostamycin, micronomicin and A Si mycin.
2. disinfecting corrosion inhibitor composition according to claim 1, wherein, described antibiotic withThe weight ratio of stannous salt is 0.8-2.5:1.
3. disinfecting corrosion inhibitor composition according to claim 1 and 2, wherein, kills with describedBacterium corrosion inhibiter is benchmark by the total amount of composition, and the content sum of antibiotic and stannous salt is that 5-100 is heavyAmount %.
4. disinfecting corrosion inhibitor composition according to claim 1 and 2, wherein, kills with describedBacterium corrosion inhibiter is benchmark by the total amount of composition, and the content sum of antibiotic and stannous salt is that 8-95 is heavyAmount %.
5. disinfecting corrosion inhibitor composition according to claim 1 and 2, wherein, described divalencePink salt is stannous chloride and/or stannous bromide.
6. disinfecting corrosion inhibitor composition according to claim 1, wherein, cephalosporins is anti-Raw element is selected from brizolina, cefalexin, Cefradine, cefadroxil, Cefaclor, cephaloThe Meng polyester sodium, cefoxitin sodium, cefuroxime, cefoperazone sodium, Cefotaxime Sodium, cefotaxime,At least one of ceftizoxime sodium and peace Qu Nanzhong.
7. disinfecting corrosion inhibitor composition according to claim 1, wherein, described sterilization inhibitionAgent also contains non oxidizing bactericide with composition, and described non oxidizing bactericide is selected from quaternary sterilizationAt least one in agent, phosphonium salt bactericidal agent and OIT.
8. disinfecting corrosion inhibitor composition according to claim 7, wherein, described non-oxidizableThe weight ratio of bactericide and stannous salt is 0.2-60:1.
9. disinfecting corrosion inhibitor composition according to claim 7, wherein, described non-oxidizableThe weight ratio of bactericide and stannous salt is 1-30:1.
10. according to the disinfecting corrosion inhibitor composition described in any one in claim 7-9, wherein,Described non oxidizing bactericide is quaternary ammonium salt type bactericidal agent, described quaternary ammonium salt type bactericidal agent and stannous saltWeight ratio is 5-40:1; Or
Described non oxidizing bactericide is phosphonium salt bactericidal agent, described phosphonium salt bactericidal agent and Bivalent TinThe weight ratio of salt is 5-25:1; Or
Described non oxidizing bactericide is OIT, the weight of described OIT and stannous saltThan being 0.2-3:1.
11. according to the disinfecting corrosion inhibitor composition described in any one in claim 7-9, wherein,Described non oxidizing bactericide is quaternary ammonium salt type bactericidal agent, described quaternary ammonium salt type bactericidal agent and stannous saltWeight ratio is 10-25:1; Or
Described non oxidizing bactericide is phosphonium salt bactericidal agent, described phosphonium salt bactericidal agent and Bivalent TinThe weight ratio of salt is 10-15:1; Or
Described non oxidizing bactericide is OIT, the weight of described OIT and stannous saltThan being 0.5-1.5:1.
Disinfecting corrosion inhibitor in 12. claim 1-11 described in any one uses composition in circulating coolingApplication in water treatment.
13. application according to claim 12, wherein, described disinfecting corrosion inhibitor use compositionConsumption is 1-20mg/L recirculated cooling water.
14. application according to claim 12, wherein, described disinfecting corrosion inhibitor use compositionConsumption is 1.5-14mg/L recirculated cooling water.
15. according to the application described in any one in claim 12-14, wherein, and described circulating coolingThe pH value of water is 7-10.
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| CN1789159A (en) * | 2005-12-05 | 2006-06-21 | 赵清顺 | Sterilization inhibitor for circulated cooling water treatment |
| CN101307349A (en) * | 2008-06-24 | 2008-11-19 | 内蒙古伊利实业集团股份有限公司 | Process for detecting hydrolysis residue of antibiotic from dairy products |
| CN101366700A (en) * | 2008-09-19 | 2009-02-18 | 浙江大学 | Hydrophilic medicament dual-microsphere formulation and preparation method thereof |
| CN101396363A (en) * | 2007-09-28 | 2009-04-01 | 重庆医药工业研究院有限责任公司 | Composite antibacterial drugs composition containing abafungin |
| CN102719835A (en) * | 2012-07-03 | 2012-10-10 | 武汉钢铁(集团)公司 | Hydrochloric acid washing corrosion and fog inhibition accelerator for hot-rolled plate |
| CN103204589A (en) * | 2013-03-06 | 2013-07-17 | 付永全 | Method for biologically treating industrial circulating water and stabilizing quality thereof |
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| CN1789159A (en) * | 2005-12-05 | 2006-06-21 | 赵清顺 | Sterilization inhibitor for circulated cooling water treatment |
| CN101396363A (en) * | 2007-09-28 | 2009-04-01 | 重庆医药工业研究院有限责任公司 | Composite antibacterial drugs composition containing abafungin |
| CN101307349A (en) * | 2008-06-24 | 2008-11-19 | 内蒙古伊利实业集团股份有限公司 | Process for detecting hydrolysis residue of antibiotic from dairy products |
| CN101366700A (en) * | 2008-09-19 | 2009-02-18 | 浙江大学 | Hydrophilic medicament dual-microsphere formulation and preparation method thereof |
| CN102719835A (en) * | 2012-07-03 | 2012-10-10 | 武汉钢铁(集团)公司 | Hydrochloric acid washing corrosion and fog inhibition accelerator for hot-rolled plate |
| CN103204589A (en) * | 2013-03-06 | 2013-07-17 | 付永全 | Method for biologically treating industrial circulating water and stabilizing quality thereof |
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