CN104628163A - Composition for bactericidal corrosion inhibitors and application thereof - Google Patents
Composition for bactericidal corrosion inhibitors and application thereof Download PDFInfo
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Abstract
The invention discloses a composition for bactericidal corrosion inhibitors and application thereof. The composition for bactericidal corrosion inhibitors contains antibiotics and a bivalent tin salt. The antibiotics are selected from at least two of macrolide antibiotics, tetracycline antibiotics, beta-lactam antibiotics and aminoglycoside antibiotics. The invention also discloses application of the composition for bactericidal corrosion inhibitors in treatment of circulating cooling water. According to the technical scheme, by applying the composition for bactericidal corrosion inhibitors to a circulating cooling water system, good bactericidal and corrosion inhibition effects can be achieved at the same time.
Description
Technical field
The present invention relates to a kind of disinfecting corrosion inhibitor composition and application thereof, particularly, relate to a kind of disinfecting corrosion inhibitor composition and the application in circulating water cooling treatment thereof.
Background technology
The running maintenance of industrial circulating cooling water system relates to the problem solving fouling, corrosion and microbiological manipulation three aspects.For solving this three problems, the cost-effective method generally adopted adds Scale inhibitors, inhibiter and sterilant.Sterilant is divided into oxidizing bactericide and non oxidizing bactericide.Conventional oxidizing bactericide has strong chlorine oil, Babysafe, organic bromine etc.; Conventional non oxidizing bactericide has quaternary ammonium salt, isothiazolinone, glutaraldehyde etc.In water treatment, the method that usual employing alternately adds oxidizing bactericide and non oxidizing bactericide carrys out the microbe population in controlled circulation water coolant.But although the chlorine series bactericidal agent instantaneous sterilization effective sterilization time length is short, and certain corrodibility is existed to carbon steel equipment.Quaternary ammonium salt easily produces resistance, and in the last few years, a lot of people was carrying out modification to quaternary ammonium salt, or searching quaternary alkylphosphonium salt replaces quaternary ammonium salt, but the lifting that sterilization effect is too large.
CN1789159A discloses a kind of disinfecting corrosion inhibitor, and this disinfecting corrosion inhibitor comprises sterilant, tensio-active agent, inhibiter, solvent and organophosphate, forms through being uniformly mixed.Described disinfecting corrosion inhibitor can play the effects such as sterilization algae removal, sludge stripping, pre-film in the recirculating cooling water system of copper material.It is narrow that this invention limits strict use range to equipment material, is mainly applicable to the recirculating cooling water system of copper material.
CN1418830A discloses a kind of both sexes disinfecting corrosion inhibitor, and this both sexes disinfecting corrosion inhibitor is made up of alkyl quaternary amine inner salt, quaternary ammonium halide, nonionogenic tenside, solvent and water.Though this disinfecting corrosion inhibitor is both sexes disinfecting corrosion inhibitor, corrosion mitigating effect is not good, and when working concentration is 40mg/L, corrosion inhibition rate only has 69%.
Microbiotic is the class secondary metabolite with antipathogen or other activity produced in life process by microorganism (comprising bacterium, fungi and actinomycetes) or high animals and plants, and other living cells can be disturbed to grow the chemical substance of function.Antibiotic antibacterial or germicidal action mechanism mainly contains 4 kinds: the synthesis of anti-bacteria cell walls, interact with cytolemma and change membrane passage, interferencing protein synthesis and suppress transcribing and copying of nucleic acid.Microbiotic is mainly for the mechanisms play effect of " bacterium has and people or other higher animal do not have ", and therefore microbiotic is multiplex with it people and animal.Also there is the agricultural antibiotic being used for farm crop at present.But do not see the report be used for by microbiotic in recirculating cooling water system.
Summary of the invention
The object of the invention is to overcome in prior art the defect being difficult to obtain sterilization and all good disinfecting corrosion inhibitor of corrosion mitigating effect, disinfecting corrosion inhibitor composition and the application thereof all preferably of a kind of sterilization and corrosion mitigating effect is provided.
To achieve these goals, the present inventor has carried out a large amount of experiments, found that, microbiotic and stannous salt is coordinated and not only has preferably sterilization effect as disinfecting corrosion inhibitor, also have good corrosion inhibition.Therefore, the invention provides a kind of disinfecting corrosion inhibitor composition, wherein, this disinfecting corrosion inhibitor composition contains microbiotic and stannous salt, and described microbiotic is selected from least two kinds in macrolide antibiotics, tetracycline antibiotics, β-lactam antibitics and aminoglycoside antibiotics.
Present invention also offers the application of above-mentioned disinfecting corrosion inhibitor composition in circulating water cooling treatment.
By technique scheme, when being used in recirculating cooling water system by disinfecting corrosion inhibitor composition of the present invention, preferably sterilization and corrosion mitigating effect can be obtained simultaneously.
Other features and advantages of the present invention are described in detail in embodiment part subsequently.
Embodiment
Below the specific embodiment of the present invention is described in detail.Should be understood that, embodiment described herein, only for instruction and explanation of the present invention, is not limited to the present invention.
Disinfecting corrosion inhibitor composition provided by the invention contains microbiotic and stannous salt, and described microbiotic is selected from least two kinds in macrolide antibiotics, tetracycline antibiotics, β-lactam antibitics and aminoglycoside antibiotics.
According to the present invention, as long as coordinate the activeconstituents as disinfecting corrosion inhibitor composition can realize object of the present invention in microbiotic and stannous salt, to the special requirement of the content of microbiotic and stannous salt, such as, with the total amount of described disinfecting corrosion inhibitor composition for benchmark, the content sum of microbiotic and stannous salt can change in 5-100 % by weight scope, under preferable case, with the total amount of described disinfecting corrosion inhibitor composition for benchmark, the content sum of microbiotic and stannous salt is 8-95 % by weight.
According to the present invention, as long as by microbiotic and stannous salt with the use of realizing object of the present invention, the weight ratio of described microbiotic and stannous salt is not particularly limited, but preferably, the weight ratio of described microbiotic and stannous salt is 0.3-7:1, is more preferably 0.8-2.5:1.
In the present invention, macrolide antibiotics refers in molecular structure containing a parent nucleus---the microbiotic of macrolide.The present invention, to the not special requirement of the kind of described macrolide antibiotics, can be the macrolide antibiotics of various routine, and all can by commercially available.Under preferable case, described macrolide antibiotics is selected from least one in erythromycin, albomycin, acetylspiramycin, mydecamycin and josamycin.
Tetracycline antibiotics refers in molecular structure a class microbiotic with tetracene structure.The present invention, to the not special requirement of the kind of described tetracycline antibiotics, can be the tetracycline antibiotics of various routine, and all can by commercially available.Under preferable case, described tetracycline antibiotics is selected from least one in tsiklomitsin, terramycin, duomycin, Doxycycline, Klinomycin and metacycline.
β-lactam antibitics refers in molecular structure the microbiotic with beta-lactam nucleus.The present invention is to the not special requirement of the kind of described β-lactam antibitics, can be the β-lactam antibitics (comprising clinical the most frequently used Penicillin antibiotics and cephalosporins etc.) of various routine, and all can by commercially available.Under preferable case, described β-lactam antibitics is cephalosporins (can be one or more in first generation cephalosporin, second generation cephalosporin, third generation cephalosporin and forth generation cynnematin).More preferably, described β-lactam antibitics is selected from least one of cephazolin sodium, Cephalexin Monohydrate Micro/Compacted, Cephradine, S 578, cefaclor, Sodium O-formylcefamole, cefoxitin sodium, cefuroxime, T-1551, cefotaxime sodium, ceftazime, ceftizoxime sodium and peace Qu Nanzhong.
Aminoglycoside antibiotics refers to containing a hexalin aglucon in molecule, the compounds combined with aminosugar (or neutral sugar) with glycosidic link.The present invention is to the not special requirement of the kind of described aminoglycoside antibiotics, can be the aminoglycoside antibiotics (comprising clinical the most frequently used streptidine derivatives class, inositol-inosamine derivatives class and 2-deoxystreptamine derivatives class etc.) of various routine, and all can by commercially available.Under preferable case, described aminoglycoside antibiotics is selected from least one in Streptomycin sulphate, gentamicin, kantlex, tobramycin, Amikacin Sulphate, Liu Suanyan NEOMYCIN SULPHATE, ribostamycin, micronomicin and A Si mycin.
According to the present invention, as long as by least two kinds in above microbiotic and stannous salt with the use of realizing object of the present invention, have no particular limits all kinds of antibiotic consumption, can be identical or different.
In the present invention, described stannous salt can be the common various stannous salts in this area, and be preferably the sub-tin of halogenation, under further preferable case, described stannous salt is tin protochloride and/or tin protobromide.
According to the present invention, in order to strengthen the sterilization corrosion mitigating effect of disinfecting corrosion inhibitor composition of the present invention further, described disinfecting corrosion inhibitor composition can also contain non oxidizing bactericide further, and described non oxidizing bactericide is selected from least one in quaternary ammonium salt type bactericidal agent, phosphonium salt bactericidal agent and isothiazolinone.When disinfecting corrosion inhibitor composition of the present invention contains non oxidizing bactericide, preferably sterilization corrosion mitigating effect also can be obtained when content sum lower (as less than 70 % by weight) of microbiotic and stannous salt.Wherein, commercially available various quaternary ammonium salt type bactericidal agent, phosphonium salt bactericidal agent and isothiazolinone all can be used for the present invention.
Described quaternary ammonium salt type bactericidal agent can be single long chain quaternary.It is R that described single long chain quaternary is preferably selected from general formula
1(R
3)
2nR
2the quaternary ammonium salt of X, wherein R
1for carbonatoms is the chain alkyl of 8-20, be preferably dodecyl, tetradecyl, hexadecyl or octadecyl; R
2for aryl or aralkyl, being preferably carbonatoms is the aralkyl of 7-11; R
3for carbonatoms is the alkyl of 1-4, be preferably methyl; X is chlorine or bromine.
Described phosphonium salt bactericidal agent can be single long chain quaternary alkylphosphonium salt.It is R that described Dan Changlian quaternary alkylphosphonium salt is preferably selected from general formula
4(R
5)
3pX quaternary alkylphosphonium salt, wherein R
4for carbonatoms is the chain alkyl of 8-20, be preferably dodecyl, tetradecyl or hexadecyl; R
5for carbonatoms is the alkyl of 1-4, be preferably butyl; X is chlorine or bromine.
Such as, described quaternary ammonium salt type bactericidal agent can be at least one in dodecyl benzyl dimethyl ammonium chloride, dodecyl dimethyl benzyl ammonium bromide, myristyl benzyl dimethyl ammonium chloride, cetalkonium chloride and octadecyl dimethyl benzyl brometo de amonio.Described phosphonium salt bactericidal agent can be at least one in dodecyl tributyl phosphonium chloride, tributyltetradecylphchloridem chloridem, phosphonium hexadecanyl-3-butyl chloride and hexadecyl tributyl phosphonium bromide.Described isothiazolinone is the commercial sterilization mould inhibitor of a class broad-spectrum high efficacy, can by commercially available, the effective constituent of described isothiazolinone is CMIT and MIT, and the weight ratio of the two can be 2-5:1 usually, be preferably 3:1, but be not limited thereto.
According to the present invention, having no particular limits the content of described non oxidizing bactericide, can be the conventional amount used of this area, and preferably, the weight ratio of described non oxidizing bactericide and stannous salt is 0.2-60:1, is more preferably 1-30:1.
Further preferably, described non oxidizing bactericide is quaternary ammonium salt type bactericidal agent, and the weight ratio of described quaternary ammonium salt type bactericidal agent and stannous salt is 5-40:1, most preferably is 10-25:1; Or
Described non oxidizing bactericide is phosphonium salt bactericidal agent, and the weight ratio of described phosphonium salt bactericidal agent and stannous salt is 5-25:1, most preferably is 10-15:1; Or
Described non oxidizing bactericide is isothiazolinone, and the weight ratio of described isothiazolinone and stannous salt is 0.2-3:1, most preferably is 0.5-1.5:1.
The present inventor finds, when adopting disinfecting corrosion inhibitor composition of the present invention to carry out circulating water cooling treatment according to mentioned kind and content proportioning, can obtain better sterilization corrosion inhibition.
Present invention also offers the application of above-mentioned disinfecting corrosion inhibitor composition in circulating water cooling treatment.
According to the present invention, the consumption of described disinfecting corrosion inhibitor composition is preferably 1-20mg/L recirculated cooling water, is more preferably 1.5-14mg/L recirculated cooling water.
Disinfecting corrosion inhibitor composition of the present invention is applicable to the various recirculated cooling water needing to add disinfecting corrosion inhibitor routinely, but, the present inventor finds, disinfecting corrosion inhibitor composition of the present invention is particularly useful for the recirculated cooling water that pH value is 7-10, therefore, preferably, the pH value of described recirculated cooling water is 7-10.
According to disinfecting corrosion inhibitor composition of the present invention, when reality uses, as long as microbiotic and stannous salt are used for can realizing object of the present invention in recirculated cooling water ordinatedly, can add after each raw material mixing again in recirculated cooling water, also each raw material directly can be added in recirculated water without mixing step, and can add, also can add successively. simultaneously
Below will be described the present invention by embodiment.In following examples, " in test water, adding * mg/L A material " means in test water, add A material, and after adding A material, the concentration of A material in test water is * mg/L test water; The microbiotic used is all purchased from Beijing the Temple of Heaven Pharmaceutical Biotechnology development company; The isothiazolinone (both CMIT and MIT mixture, the two weight ratio is 3:1, and effective content is 1.6%) used is purchased from Beijing Tianqing Chemical Co., Ltd.; The water quality of test water 1 is: Ca
2+(with CaCO
3meter) content is 229.4mg/L, basicity is (with CaCO
3meter) be 232.1mg/L, pH value is 7.5; The water quality of test water 2 is: Ca
2+(with CaCO
3meter) content is 97mg/L, basicity is (with CaCO
3meter) be 157mg/L, pH value is 7.8; The measuring method of each parameter is as follows:
Ca
2+: reference standard GB/T6910-2006;
Basicity: reference standard GB/T15451-2006;
PH value: reference standard GB/T6920-1986.
The measuring method of erosion rate is: be fixed on lacing film instrument by the test piece of 20# qualitative carbon steel, put into and added the test water of medicament by each embodiment and comparative example, steady temperature is 45 ± 1 DEG C, keeps rotating speed 75rpm to rotate 72h, the weight of test piece before and after record test, calculates erosion rate.Erosion rate is defined as the inhibition efficiency of corrosion inhibiting and descaling agent.
The calculation formula of erosion rate (F) is: F=(C × △ W)/(A × T × ρ), wherein,
C: computational constant, with mm/a(millimeter/year) for unit time, C=8.76 × 10
7
△ W: the corrosion weight loss (g) of test specimen
A: the area (cm of test specimen
2)
T: corrosion test time (h)
ρ: the density (kg/m of material for test
3)
Bactericidal property evaluation method is as follows: added by medicament in test water and (need the sodium hydroxide solution of the use 2 % by weight of adjust ph to be adjusted to and specify numerical value), do heterotrophism Counting alive microbial in 1h, 4h, 8h, 24h, 48h and 72h sampling adding medicament respectively, the initial heterotrophic bacterium number of test water is 1.5 × 10
6individual/ml.Heterotrophic bacterium number measuring method is as follows: get the test water being added with medicament, adopts former water 10 times of dilution technologies, test water is diluted to suitable multiple, and is inoculated in culture dish by the water sample of corresponding extension rate in sterilisable chamber.Then aseptic culture medium being poured in culture dish, mix with water sample, cultivating 72 ± 4h etc. being inverted after culture medium solidifying to be placed in the incubator of 29 ± 1 DEG C.After cultivation, take out culture dish, select those culture dish with 30-300 bacterium colony to count, colony number is multiplied by the heterotrophic bacterium number that corresponding extension rate is this water sample.The initial heterotrophic bacterium number of test water is 1.5 × 10
6individual/ml.
Embodiment 1
0.9mg/L erythromycin is added in test water 1,0.9mg/L cephazolin sodium, 0.8mg/L tin protochloride, by 2 % by weight sodium hydroxide adjust ph to 9.5, the insulation can of 29 ± 1 DEG C is put into after shaking up, sampling analysis heterotrophic bacterium number in required time, and carry out the determination test of erosion rate, the results are shown in Table 1.
Embodiment 2
In test water 1, add 0.8mg/L albomycin, 0.8mg/L Cephalexin Monohydrate Micro/Compacted, 0.7mg/L tin protochloride, after shaking up, put into the insulation can of 29 ± 1 DEG C, in required time sampling analysis heterotrophic bacterium number, and carry out the determination test of erosion rate, the results are shown in Table 1.
Embodiment 3
0.7mg/L acetylspiramycin is added in test water 1,0.7mg/L Streptomycin sulphate, 0.6mg/L tin protochloride, by 2 % by weight sodium hydroxide adjust ph to 8.0, the insulation can of 29 ± 1 DEG C is put into after shaking up, sampling analysis heterotrophic bacterium number in required time, and carry out the determination test of erosion rate, the results are shown in Table 1.
Embodiment 4
In test water 1, add 0.6mg/L tsiklomitsin, 0.6mg/L Cephradine, 0.5mg/L tin protochloride, after shaking up, put into the insulation can of 29 ± 1 DEG C, in required time sampling analysis heterotrophic bacterium number, and carry out the determination test of erosion rate, the results are shown in Table 1.
Embodiment 5
In test water 2, add 0.5mg/L terramycin, 0.5mg/L gentamicin, 0.4mg/L tin protobromide, after shaking up, put into the insulation can of 29 ± 1 DEG C, in required time sampling analysis heterotrophic bacterium number, and carry out the determination test of erosion rate, the results are shown in Table 1.
Embodiment 6
In test water 2, add 0.4mg/L S 578,0.4mg/L kantlex, 0.7mg/L tin protochloride, after shaking up, put into the insulation can of 29 ± 1 DEG C, in required time sampling analysis heterotrophic bacterium number, and carry out the determination test of erosion rate, the results are shown in Table 1.
Embodiment 7
In test water 1, add 0.3mg/L cefaclor, 0.3mg/L tobramycin, 0.6mg/L tin protochloride, after shaking up, put into the insulation can of 29 ± 1 DEG C, in required time sampling analysis heterotrophic bacterium number, and carry out the determination test of erosion rate, the results are shown in Table 1.
Embodiment 8
0.2mg/L mydecamycin is added in test water 2,0.2mg/L Sodium O-formylcefamole, 0.5mg/L tin protochloride, 12mg/L dodecyl benzyl dimethyl ammonium chloride, the insulation can of 29 ± 1 DEG C is put into after shaking up, sampling analysis heterotrophic bacterium number in required time, and carry out the determination test of erosion rate, the results are shown in Table 1.
Embodiment 9
0.2mg/L josamycin is added in test water 2,0.2mg/L cefoxitin sodium, 0.2mg/L A Si mycin, 0.4mg/L tin protochloride, 10mg/L dodecyl dimethyl benzyl ammonium bromide, puts into the insulation can of 29 ± 1 DEG C after shaking up, in required time sampling analysis heterotrophic bacterium number, and carry out the determination test of erosion rate, the results are shown in Table 1.
Embodiment 10
0.3mg/L metacycline is added in test water 1,0.3mg/L Amikacin Sulphate, 0.5mg/L tin protochloride, 7mg/L dodecyl tributyl phosphonium chloride, the insulation can of 29 ± 1 DEG C is put into after shaking up, sampling analysis heterotrophic bacterium number in required time, and carry out the determination test of erosion rate, the results are shown in Table 1.
Embodiment 11
0.2mg/L ceftazidime is added in test water 1, add 0.3mg/L Liu Suanyan NEOMYCIN SULPHATE, 0.5mg/L tin protochloride, 6mg/L tributyltetradecylphchloridem chloridem, the insulation can of 29 ± 1 DEG C is put into after shaking up, sampling analysis heterotrophic bacterium number in required time, and carry out the determination test of erosion rate, the results are shown in Table 1.
Embodiment 12
0.2mg/L ceftizoxime sodium is added, 0.4mg/L ribostamycin, 0.5mg/L tin protochloride in test water 1,0.7mg/L isothiazolinone, puts into the insulation can of 29 ± 1 DEG C after shaking up, in required time sampling analysis heterotrophic bacterium number, and carry out the determination test of erosion rate, the results are shown in Table 1.
Embodiment 13
In test water 2, add 0.3mg/L pacify Qu Nan, 0.3mg/L micronomicin, 0.6mg/L tin protochloride, 0.4mg/L isothiazolinone, puts into the insulation can of 29 ± 1 DEG C after shaking up, in required time sampling analysis heterotrophic bacterium number, and carry out the determination test of erosion rate, the results are shown in Table 1.
Embodiment 14
0.4mg/L duomycin is added in test water 2,0.4mg/L cefuroxime, 0.5mg/L tin protochloride, 10mg/L myristyl benzyl dimethyl ammonium chloride, 0.5mg/L isothiazolinone, puts into the insulation can of 29 ± 1 DEG C after shaking up, in required time sampling analysis heterotrophic bacterium number, and carry out the determination test of erosion rate, the results are shown in Table 1.
Embodiment 15
0.3mg/L Doxycycline is added in test water 1,0.4mg/L T-1551,0.5mg/L tin protobromide, 6mg/L cetalkonium chloride, 5mg/L phosphonium hexadecanyl-3-butyl chloride, puts into the insulation can of 29 ± 1 DEG C after shaking up, in required time sampling analysis heterotrophic bacterium number, and carry out the determination test of erosion rate, the results are shown in Table 1.
Embodiment 16
0.3mg/L Klinomycin is added in test water 2,0.3mg/L cefotaxime sodium, 0.6mg/L tin protochloride, 5mg/L octadecyl dimethyl benzyl brometo de amonio, 5mg/L hexadecyl tributyl phosphonium bromide, 0.3mg/L isothiazolinone, the insulation can of 29 ± 1 DEG C is put into after shaking up, sampling analysis heterotrophic bacterium number in required time, and carry out the determination test of erosion rate, the results are shown in Table 1.
Embodiment 17
In test water 1, add 0.1mg/L erythromycin, 0.7mg/L cephazolin sodium, 1.8mg/L tin protochloride, after shaking up, put into the insulation can of 29 ± 1 DEG C, in required time sampling analysis heterotrophic bacterium number, and carry out the determination test of erosion rate, the results are shown in Table 1.
Embodiment 18
In test water 1, add 0.3mg/L erythromycin, 0.1mg/L cephazolin sodium, 2.2mg/L tin protochloride, after shaking up, put into the insulation can of 29 ± 1 DEG C, in required time sampling analysis heterotrophic bacterium number, and carry out the determination test of erosion rate, the results are shown in Table 1.
Comparative example 1
In test water, add 12.9mg/L dodecyl benzyl dimethyl ammonium chloride, after shaking up, put into the insulation can of 29 ± 1 DEG C, in required time sampling analysis heterotrophic bacterium number, and carry out the determination test of erosion rate, the results are shown in Table 1.
Comparative example 2
In test water, add 8.1mg/L dodecyl tributyl phosphonium chloride, put into the insulation can of 29 ± 1 DEG C after shaking up, in required time sampling analysis heterotrophic bacterium number, and carry out the determination test of erosion rate, the results are shown in Table 1.
Comparative example 3
In test water, add 1.8mg/L isothiazolinone, after shaking up, put into the insulation can of 29 ± 1 DEG C, in required time sampling analysis heterotrophic bacterium number, and carry out the determination test of erosion rate, the results are shown in Table 1.
Comparative example 4
In test water 1, add 1.3mg/L erythromycin, 1.3mg/L cephazolin sodium, after shaking up, put into the insulation can of 29 ± 1 DEG C, in required time sampling analysis heterotrophic bacterium number, and carry out the determination test of erosion rate, the results are shown in Table 1.
Comparative example 5
In test water 1, add 2.6mg/L tin protochloride, after shaking up, put into the insulation can of 29 ± 1 DEG C, in required time sampling analysis heterotrophic bacterium number, and carry out the determination test of erosion rate, the results are shown in Table 1.
Comparative example 6
In test water 1, do not add any medicament, carry out the determination test of erosion rate, the results are shown in Table 1.
Table 1
Represent that measured heterotrophic bacterium number has exceeded starter bacteria number as can be seen from table 1("/") result, disinfecting corrosion inhibitor composition of the present invention there is excellent sterilization effect in sterilization and the sterilization time length long, meanwhile, it also shows excellent corrosion inhibition in inhibition.
Especially, the result of embodiment 1 with embodiment 17 and 18 is compared and can find out, more excellent sterilization corrosion mitigating effect can be obtained by the preferred weight ratio of the present invention with the use of microbiotic and stannous salt.Embodiment 8,10 and 12 is compared can find out with the result of comparative example 1-3 respectively, by non oxidizing bactericide and microbiotic and stannous salt with the use of than only using non oxidizing bactericide to show more excellent sterilization corrosion inhibition.In addition, the result of each embodiment (particularly embodiment 1) with comparative example 4 and 5 is compared and can find out, microbiotic is coordinated with stannous salt during the activeconstituents as disinfecting corrosion inhibitor composition and could obtain excellent sterilization corrosion mitigating effect.
More than describe the preferred embodiment of the present invention in detail; but the present invention is not limited to the detail in above-mentioned embodiment, within the scope of technical conceive of the present invention; can carry out multiple simple variant to technical scheme of the present invention, these simple variant all belong to protection scope of the present invention.
It should be noted that in addition, each concrete technical characteristic described in above-mentioned embodiment, in reconcilable situation, can be combined by any suitable mode, in order to avoid unnecessary repetition, the present invention illustrates no longer separately to various possible array mode.
In addition, also can carry out arbitrary combination between various different embodiment of the present invention, as long as it is without prejudice to thought of the present invention, it should be considered as content disclosed in this invention equally.
Claims (11)
1. a disinfecting corrosion inhibitor composition, it is characterized in that, this disinfecting corrosion inhibitor composition contains microbiotic and stannous salt, and described microbiotic is selected from least two kinds in macrolide antibiotics, tetracycline antibiotics, β-lactam antibitics and aminoglycoside antibiotics.
2. disinfecting corrosion inhibitor composition according to claim 1, wherein, the weight ratio of described microbiotic and stannous salt is 0.3-7:1, is preferably 0.8-2.5:1.
3. disinfecting corrosion inhibitor composition according to claim 1 and 2, wherein, with the total amount of described disinfecting corrosion inhibitor composition for benchmark, the content sum of microbiotic and stannous salt is 5-100 % by weight, is preferably 8-95 % by weight.
4. disinfecting corrosion inhibitor composition according to claim 1 and 2, wherein, described macrolide antibiotics is selected from least one in erythromycin, albomycin, acetylspiramycin, mydecamycin and josamycin;
Described tetracycline antibiotics is selected from least one in tsiklomitsin, terramycin, duomycin, Doxycycline, Klinomycin and metacycline;
Described β-lactam antibitics is cephalosporins, preferably, at least one of cephazolin sodium, Cephalexin Monohydrate Micro/Compacted, Cephradine, S 578, cefaclor, Sodium O-formylcefamole, cefoxitin sodium, cefuroxime, T-1551, cefotaxime sodium, ceftazime, ceftizoxime sodium and peace Qu Nanzhong is selected from;
Described aminoglycoside antibiotics is selected from least one in Streptomycin sulphate, gentamicin, kantlex, tobramycin, Amikacin Sulphate, Liu Suanyan NEOMYCIN SULPHATE, ribostamycin, micronomicin and A Si mycin.
5. disinfecting corrosion inhibitor composition according to claim 1 and 2, wherein, described stannous salt is tin protochloride and/or tin protobromide.
6. disinfecting corrosion inhibitor composition according to claim 1, wherein, described disinfecting corrosion inhibitor composition is also containing non oxidizing bactericide, and described non oxidizing bactericide is selected from least one in quaternary ammonium salt type bactericidal agent, phosphonium salt bactericidal agent and isothiazolinone.
7. disinfecting corrosion inhibitor composition according to claim 6, wherein, the weight ratio of described non oxidizing bactericide and stannous salt is 0.2-60:1, is preferably 1-30:1.
8. the disinfecting corrosion inhibitor composition according to claim 6 or 7, wherein, described non oxidizing bactericide is quaternary ammonium salt type bactericidal agent, and the weight ratio of described quaternary ammonium salt type bactericidal agent and stannous salt is 5-40:1, is preferably 10-25:1; Or
Described non oxidizing bactericide is phosphonium salt bactericidal agent, and the weight ratio of described phosphonium salt bactericidal agent and stannous salt is 5-25:1, is preferably 10-15:1; Or
Described non oxidizing bactericide is isothiazolinone, and the weight ratio of described isothiazolinone and stannous salt is 0.2-3:1, is preferably 0.5-1.5:1.
9. the application of disinfecting corrosion inhibitor composition in circulating water cooling treatment in claim 1-8 described in any one.
10. application according to claim 9, wherein, the consumption of described disinfecting corrosion inhibitor composition is 1-20mg/L recirculated cooling water, is preferably 1.5-14mg/L recirculated cooling water.
11. application according to claim 9 or 10, wherein, the pH value of described recirculated cooling water is 7-10.
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| CN101307349A (en) * | 2008-06-24 | 2008-11-19 | 内蒙古伊利实业集团股份有限公司 | Process for detecting hydrolysis residue of antibiotic from dairy products |
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| CN101396363A (en) * | 2007-09-28 | 2009-04-01 | 重庆医药工业研究院有限责任公司 | Composite antibacterial drugs composition containing abafungin |
| CN102719835A (en) * | 2012-07-03 | 2012-10-10 | 武汉钢铁(集团)公司 | Hydrochloric acid washing corrosion and fog inhibition accelerator for hot-rolled plate |
| CN103204589A (en) * | 2013-03-06 | 2013-07-17 | 付永全 | Method for biologically treating industrial circulating water and stabilizing quality thereof |
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| CN1789159A (en) * | 2005-12-05 | 2006-06-21 | 赵清顺 | Sterilization inhibitor for circulated cooling water treatment |
| CN101396363A (en) * | 2007-09-28 | 2009-04-01 | 重庆医药工业研究院有限责任公司 | Composite antibacterial drugs composition containing abafungin |
| CN101307349A (en) * | 2008-06-24 | 2008-11-19 | 内蒙古伊利实业集团股份有限公司 | Process for detecting hydrolysis residue of antibiotic from dairy products |
| CN101366700A (en) * | 2008-09-19 | 2009-02-18 | 浙江大学 | Hydrophilic medicament dual-microsphere formulation and preparation method thereof |
| CN102719835A (en) * | 2012-07-03 | 2012-10-10 | 武汉钢铁(集团)公司 | Hydrochloric acid washing corrosion and fog inhibition accelerator for hot-rolled plate |
| CN103204589A (en) * | 2013-03-06 | 2013-07-17 | 付永全 | Method for biologically treating industrial circulating water and stabilizing quality thereof |
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