CN104589651B - Photocuring printing device and method - Google Patents
Photocuring printing device and method Download PDFInfo
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- CN104589651B CN104589651B CN201510025512.8A CN201510025512A CN104589651B CN 104589651 B CN104589651 B CN 104589651B CN 201510025512 A CN201510025512 A CN 201510025512A CN 104589651 B CN104589651 B CN 104589651B
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Abstract
Photocuring printing device and method are disclosed, for forming three-dimensional structure in photo-sensitive hydrogel according to the image of Computer Storage, including：Digital projection unit, for by image projection to photo-sensitive hydrogel layer；Photo-sensitive hydrogel solidified cell, for providing photo-sensitive hydrogel to form photo-sensitive hydrogel layer, and successively solidifies according to the image of projection in photo-sensitive hydrogel layer；And computer control unit, for providing image to digital projection unit and controlling image space of the image of projection in photo-sensitive hydrogel layer, wherein, the photo-sensitive hydrogel solidified cell includes guide rod and is arranged along the carrying tablet of guide rod movement, and the lower surface of the carrying tablet limits the upper liquid level of photo-sensitive hydrogel layer.The photocuring printing device can high accuracy and print three-dimensional structure at a high speed.
Description
Technical field
The present invention relates to 3D printing technique, more particularly, to photocuring printing device and method.
Background technology
3D printing belongs to one kind of rapid shaping technique, also referred to as " increasing material manufacturing " technology (Additive process).
At present, the material that can be used for 3D printing is very limited, and predominantly plastics, ceramics etc. easily moulding material and are capable of photopolymerization
Light-sensitive material.
3D biometric prints are mainly used in field of tissue engineering technology, i.e., first print biological support, are then trained cell
It is inoculated on biological support after supporting amplification.Cell-biological support compound is transplanted in vivo after cultivating in vitro.In this body
In system, cell cannot be planted inside biological support, it is impossible to built internal more complicated tissue and organ, cannot especially be realized
The tissue and organ of structure be connected by blood vessel in vivo.
The development trend of 3D biometric prints is to use active somatic cell, or the complex of active somatic cell-biomaterial is direct
Printing tissue or organ.Due to the diversity and the complexity of institutional framework of internal cell, the success report of this respect is still very
It is few.Organovo companies of the U.S. successfully 20 layers of hepatic parenchymal cells of 3D printing and HSCs, construct only two kinds
The miniature liver with biological function of cell composition.The simple structure of the miniature liver, can replace the organ of patient also needs
Further experimental result is wanted to confirm.
3D biometric prints can be carried out using ink jet type 3D printing equipment or photocuring printing device.Ink jet type 3D printing
Equipment, such as purchased from the Project HD3500 type printers of 3-D Systems companies of the U.S., it is possible to achieve minimum thickness reach
To 16 microns, structural resolution reaches 50 microns.Due to lacking the thermoplastic material of bioactive functions, the printer can not be direct
Carry out biometric print.Alternatively, cardiovascular wax pattern is printed using the printer, is then fallen by polymer colloid material
Mould forms micro-tube.However, the inside out-of-flatness of the micro-tube, its structural resolution can not meet requirement.Photocuring is beaten
Printing apparatus, such as, purchased from the Femtosecond Laser Direct Writer of Zeiss, Germany company, can directly print biology
Active material, and printing precision higher is realized, such as two dimensional character yardstick reaches 100 nanometers, and three-dimensional feature yardstick is less than
150 nanometers.The precision of photocuring printing device can meet the requirement of 3D biometric prints.
The size and speed of above-mentioned photocuring printing device printing objects are very restricted.Such as printing objects
Stroke be less than 100 microns.Femtosecond Laser Direct Writer are that individual element is printed, namely pointwise laser
Scanning solidification, so as to limit print speed.If for constructing the three-dimensional biological structure that individual cells size is up to 30 microns,
Then time-write interval needs are calculated with number of days.The long time-write interval is all not for the working life and energy consumption of two-photon laser
Profit.
The content of the invention
A kind of photocuring it is an object of the invention to provide high accuracy that can be used for 3D biometric prints and high speed is beaten
Printing apparatus and method.
According to an aspect of the present invention, there is provided a kind of photocuring printing device, exist for the image according to Computer Storage
Three-dimensional structure is formed in photo-sensitive hydrogel, including：Digital projection unit, for by image projection to photo-sensitive hydrogel layer；Light
Quick hydrogel solidified cell, for providing photo-sensitive hydrogel to form photo-sensitive hydrogel layer, and according to the image for projecting in light
Successively solidify in quick hydrogel layer；And computer control unit, for providing image and control throwing to digital projection unit
Image space of the image of shadow in photo-sensitive hydrogel layer, wherein, the photo-sensitive hydrogel solidified cell includes guide rod and sets
The carrying tablet moved along guide rod is set to, the lower surface of the carrying tablet limits the upper liquid level of photo-sensitive hydrogel layer.
Preferably, the digital projection unit includes：DMD, including the array and root that multiple micro mirrors are constituted
The on off state of micro mirror is set according to described image；Total reflection prism, it is micro- for the directional light produced from light source to be reflexed into numeral
Mirror device；And projecting lens, for will be in open state micro mirror reflected light projects to photo-sensitive hydrogel layer in, so as to
The focal plane position imaging of projecting lens.
Preferably, the digital projection unit also includes shutter, is cut for the control command according to computer control unit
Disconnected or recovery light path.
Preferably, the photo-sensitive hydrogel solidified cell also includes：Platform, including for supporting photo-sensitive hydrogel layer
Surface；Injection channel, is arranged on platform interior, the upper surface for photo-sensitive hydrogel to be delivered to platform；Lowering or hoisting gear, is used for
Adjust the upper level of platform；Ascending pipe, for accommodating photo-sensitive hydrogel and being connected with injection channel；Injection propulsion dress
Put, for the photo-sensitive hydrogel in ascending pipe to be advanced into injection channel；And injecting controller, for controlling injection propulsion
The action of device, so as to control injection rate.
Preferably, the carrying tablet is quartz glass plate.
Preferably, the lower surface of the carrying tablet is by hydrophobic treatment, or coated mineral oil, so as to obtain hydrophobic table
Face.
Preferably, the upper surface of the platform is by hydrophobic treatment, or coated mineral oil, so as to obtain hydrophobic surface.
Preferably, described image is the sectional slice image of three-dimensional structure.
According to another aspect of the present invention, there is provided a kind of photocuring Method of printing, for the image according to Computer Storage
Three-dimensional structure is formed in photo-sensitive hydrogel, including：Implantation step, forms photo-sensitive hydrogel layer between platform and carrying tablet,
The upper liquid level of photo-sensitive hydrogel layer is limited using the lower surface of carrying tablet；Step of exposure, the imaging surface in photo-sensitive hydrogel layer
Produce projected image so that the appropriate section solidification of photo-sensitive hydrogel layer.
Preferably, the imaging surface is the focal plane of projecting lens.
Preferably, before implantation step, also enter including at least one the lower surface to carrying tablet and the upper surface of platform
Row hydrophobic treatment, or coated mineral oil, to prevent photocurable layers to be bonded thereon.
Preferably, the distance in implantation step between carrying tablet and the upper surface of platform changes with injection rate, holds
The movement of slide glass is limited by guide rod, so as to be only capable of vertically moving relative to imaging surface.
Preferably, between implantation step and step of exposure, also including moving step, wherein being moved in the moving step
Moving platform so that carrying tablet remains predetermined value relative to the distance of imaging surface.
Preferably, step, moving step and step of exposure are repeatedly injected, since the lower surface of carrying tablet, from bottom to up
Successively form the every aspect of three-dimensional structure.
Preferably, after the implant step, also including moving step, wherein the mobile platform in the moving step, makes
Imaging surface be located at previous aspect photocurable layers upper surface top, and the photocurable layers relative to previous aspect distance
Keep predetermined value.
Preferably, moving step and step of exposure are repeated, since the upper surface of platform, is successively formed from bottom to up three-dimensional
The every aspect of structure.
Preferably, pre-set the position of platform and keep constant in photocuring print procedure so that imaging surface begins
Position of the final position above the upper surface of platform.
Preferably, step and step of exposure are repeatedly injected so that in implantation step, in the upper surface of platform and photocuring
The intermediate layer of photo-sensitive hydrogel is formed between layer, and the imaging surface is located in intermediate layer.
Preferably, step and step of exposure are repeatedly injected, since the upper surface of platform, are successively formed from top to bottom three-dimensional
The every aspect of structure.
According to an embodiment of the invention in the photo-sensitive hydrogel layer of photocuring printing device and method below carrying tablet
Form the every aspect of three-dimensional structure.Due to successively carrying out curing molding, for individual element printing, print speed is more
Hurry up.The three-dimensional structure for ultimately forming can include complicated shape, such as, comprising hole, pipeline etc., to be formed such that it is able to be used for
Biological tissue.
In photocuring printing device, the lower surface of carrying tablet limits the upper liquid level of photo-sensitive hydrogel layer.Carrying tablet peace
Platform limits photo-sensitive hydrogel layer together, and photo-sensitive hydrogel is accommodated without the container for adding.Carrying tablet may be provided in
The positioning reference of image planes so that the vertical resolution of printing is improved.The transverse shifting of carrying tablet is limited using guide rod, such that it is able to
Avoid the staggered floor phenomenon between different aspects so that the horizontal resolution of printing is improved.
In a preferred embodiment, photo-sensitive hydrogel is injected using ascending pipe in print procedure.Due to injecting new light
Quick hydrogel, can mitigate the influence to original photo-sensitive hydrogel in the exposure process of previous step.Even if the multiple layers of printing
The three-dimensional structure in face, it is also ensured that the stability of photocuring characteristic in the exposure process of each aspect.Light is not only contributed to consolidate
The control of change process, and due to the three-dimensional structure of more aspects can be printed so that the printing stroke of vertical direction increases.
Additionally, the photocuring printing device is by total internal reflection projecting light path, high accuracy mechanical universal mobile platform and property high
Energy computer image processing is combined, and can avoid excessively complicated crowded light path design and realize high-precision printing.
Brief description of the drawings
By description referring to the drawings to the embodiment of the present invention, of the invention above-mentioned and other purposes, feature and
Advantage will be apparent from, in the accompanying drawings：
Fig. 1 shows the basic structure schematic diagram of photocuring printing device according to an embodiment of the invention；
Fig. 2 shows the operation principle schematic diagram of the DMD used in photocuring printing device；
Fig. 3 a to 3c show the schematic diagram of each step of the photocuring Method of printing of first embodiment of the invention；
Fig. 4 a to 4c show the schematic diagram of each step of photocuring Method of printing according to the second embodiment of the present invention；
Fig. 5 a to 5c show the schematic diagram of each step of photocuring Method of printing according to the third embodiment of the invention.
Specific embodiment
Various embodiments of the present invention are more fully described hereinafter with reference to accompanying drawing.In various figures, identical element
Represented using same or similar reference.For the sake of clarity, the various pieces in accompanying drawing are not necessarily to scale.
The present invention can be presented in a variety of manners, some of them example explained below.
Fig. 1 shows the basic structure schematic diagram of photocuring printing device according to an embodiment of the invention.The photocuring is beaten
Printing apparatus include digital projection unit 100, photo-sensitive hydrogel solidified cell 200 and computer control unit 300.
Digital projection unit 100 include ultraviolet (UV) light source 110, shutter 120, optical filtering 130, condenser 140, it is complete in it is anti-
Penetrate (TIR) prism 150, DMD (DMD) 160 and projecting lens 180.UV light is sent from UV light sources 110.Shutter
120 can cut off light path.UV light forms directional light after optical filtering 130 is filtered, condenser 140 is focused on, with more than critical angle
The first incidence angle enter TIR prism 150, by after total reflection change light direction, then uniform irradiation is on DMD 160.
UV light sources 110 are for example placed in the focus of the side of condenser 140, so as to be produced in the opposite side of condenser 140
Raw directional light.Optical filtering 130 is, for example, Cold Mirrors, for stopping infrared ray and allowing UV light to pass through.TIR prism 150 includes two
Plant the medium of different refractivity, such as glass and air.In the interface of two media, if light is from the medium of high index of refraction
(such as glass) is incident and incident angle is more than critical angle, then Jie that incident ray all will be reflected without entering low-refraction
Matter (such as air).
DMD 160 controls the on off state of each micro mirror according to control signal.Under the irradiation of directional light, in DMD 160
In in "On" state micro mirror produce reflected light formed mask graph.Reflected light from micro mirror is with less than critical angle
Two incidence angles enter TIR prism 150.In the interface of two media, light is incident from the medium (such as glass) of high index of refraction,
However, due to the second incidence angle be less than critical angle, incident light at least partially into low-refraction medium (such as air) from
And pass through TIR prism 150.The projection focal plane of projecting lens 180 is located in photo-sensitive hydrogel solidified cell 200.The shapes of DMD 160
Into mask graph be imaged on focal plane.
Photo-sensitive hydrogel solidified cell 200 includes platform 210, guide rod 220, quartz glass plate 230, injection channel 240, liter
Falling unit 260, injecting controller 280, injection propulsion plant 281 and ascending pipe 282.Lowering or hoisting gear 260 can adjust platform
210 or the height of quartz glass plate 230.The displacement of the control injection propulsion plant 281 of injecting controller 280 so that injection
Photo-sensitive hydrogel in pipe 282 enters injection channel 240 via the pipeline being connected with ascending pipe, then reaches the upper of platform 210
Surface.Due to the surface tension of photo-sensitive hydrogel, the photo-sensitive hydrogel injected below quartz glass plate 230 forms thin layer.Control
Injection rate processed can change the thickness of photo-sensitive hydrogel layer 250.Guide rod 220 limits the lateral displacement position of quartz glass plate 230,
So that in the thickness change of photo-sensitive hydrogel layer 250, quartz glass plate 230 is only capable of being moved along short transverse.
The container that above-mentioned photo-sensitive hydrogel layer 250 need not be added.In alternate embodiments, if it is desired, can be by
Guide rod 220 and quartz glass plate 230 are placed in container together.The bottom end opening of container is connected with injection channel 240.In container
During interior receiving photo-sensitive hydrogel, quartz glass plate 230 is located on the liquid level of photo-sensitive hydrogel, and as liquid level is moved together
It is dynamic.
Computer control unit 300 connects the shutter 120 and DMD 160 in digital projection unit 100 respectively, and photosensitive
Lowering or hoisting gear 260 and injecting controller 280 in hydrogel solidified cell 200.Computer control unit 300 stores printing objects
Three-dimensional structure sectional slice view data.
Fig. 2 shows the operation principle schematic diagram of the DMD used in photocuring printing device.As an example,
Two micro mirrors 162 and 163 made of aluminum are only set on substrate 161.Under control of the control signal, micro mirror 162 and 163
Can be deflected around respective rotating shaft 164 and 165.As shown in Fig. 2 the surface deflections -12 of micro mirror 162 are spent so that light direction
Light path.Correspondingly, micro mirror 162 is in "On" state.The surface deflections+12 of micro mirror 163 are spent so that light deviates light path.Accordingly
Ground, micro mirror 164 is in "Off" state.In micro mirror array, each micro mirror is used as a pixel, so that micro mirror array can be represented
One mask graph.
The DMD can for example use the digital micromirror array chips of DLP 9500 purchased from Texas Instruments.
The digital micromirror array chip is respectively the aluminium micro mirror array of 10.8um × 10.8um comprising 1920 × 1080 areas.Each is micro-
Mirror can address access, and ± 12 degree of inclination angle is deflected according to the control of corresponding control signal, make its corresponding pixel
Point light beam direction deviates light path.The switching rate of micro mirror may be up to 23KHz, therefore micro mirror array can at a high speed produce dynamic to cover
Mould figure.
Fig. 3 a to 3c show the schematic diagram of each step of the photocuring Method of printing of first embodiment of the invention.
For brevity, the digital projection unit 100 not shown in subsequent accompanying drawing, computer control unit 300, this
The injecting controller 280 of outer also not shown photo-sensitive hydrogel solidified cell 200, injection propulsion plant 281 and ascending pipe 282.
It is appreciated that these unshowned parts are still the part of photocuring printing device of the invention, and in photocuring
Respective effect is played in Method of printing.
On the other hand, subsequent shown in the drawings of the dotted line in photo-sensitive hydrogel layer, to represent projecting lens
The position of 180 focal plane.
The photocuring Method of printing includes multiple alternate implantation step, moving step and step of exposure, in photosensitive water-setting
The sectional slice image of every aspect is successively formed in glue-line 250.As an example, showing to form three aspects in Fig. 3 a to 3c
Sectional slice image embodiment.
In this embodiment, in the coated one layer of mineral oil (being not shown) of lower surface of quartz glass plate 230.The ore deposit
Together with thing oil guarantee quartz glass plate 230 will not be solidified to following hydrogel, so as to the photocurable layers for preventing from being formed
With the bonding between quartz glass plate 230.In alternate embodiments, the lower surface of quartz glass plate 203 can be dredged
Water process, due to foring hydrophobic surface thus not needing coated mineral oil.
In the first implantation step, shutter 120 closes to cut off light path.Injecting controller 280 causes injection propulsion plant
281 actions, photo-sensitive hydrogel is injected via injection channel 240, and the photosensitive water-setting of suitable thickness is formed in the upper surface of platform 210
Glue-line 250.
In the first moving step, lowering or hoisting gear 260 moves up and down platform 210 so that the focal plane position of projecting lens 180
In the inside of photo-sensitive hydrogel layer 250, the position of the lower section of quartz glass plate 230 is located exactly at.
In the first step of exposure, shutter 120 is opened to recover light path.UV light reaches DMD 160.Computer controls list
The view data of the first sectional slice is supplied to DMD 160 by unit 300, controls the micro mirror array unit corresponding with each pixel
On off state, so as to form the mask graph consistent with sectional slice image.Under the irradiation of UV light, photo-sensitive hydrogel layer
250 is corresponding with the focal plane of projecting lens 180 partially cured, and forms corresponding with the mask graph of DMD 160 consolidating
Change part, so that the first photocurable layers L1 consistent with the first sectional slice image is obtained, as shown in Figure 3 a.
In the second implantation step, shutter 120 closes to cut off light path.Injecting controller 280 causes injection propulsion plant
281 actions, photo-sensitive hydrogel is injected via injection channel 240, so that the thickness of photo-sensitive hydrogel layer 250 increases.
Due to there is mineral oil between the photocurable layers L1 of quartz glass plate 230 and first, photo-sensitive hydrogel can ooze
Enter between the photocurable layers L1 of quartz glass plate 230 and first.Or, photo-sensitive hydrogel is via the pattern in the first photocurable layers L1
The connected pore channel of formation enters between the photocurable layers L1 of quartz glass plate 230 and first.It is solid in the light of quartz glass plate 230 and first
Change formation photo-sensitive hydrogel intermediate layer between layer L1.
In the second moving step, lowering or hoisting gear 260 moves down platform 210 so that the focal plane of projecting lens 180 is located at light
The inside in quick hydrogel intermediate layer, is located exactly at the position of the lower section of quartz glass plate 230.
In the second step of exposure, shutter 120 is opened to recover light path.UV light reaches DMD 160.Computer control unit
The view data of the second sectional slice is supplied to DMD 160 by 300, controls the micro mirror array unit corresponding with each pixel
On off state, so as to form the mask graph consistent with sectional slice image.Under the irradiation of UV light, photo-sensitive hydrogel layer 250
It is corresponding with the focal plane of projecting lens 180 partially cured, and form the solidified portion corresponding with the mask graph of DMD 160
Point, so that the second photocurable layers L2 consistent with the second sectional slice image is obtained, as shown in Figure 3 b.
In the 3rd implantation step, shutter 120 closes to cut off light path.Injecting controller 280 causes injection propulsion plant
281 actions, photo-sensitive hydrogel is injected via injection channel 240, so that the thickness of photo-sensitive hydrogel layer 250 increases.
Due to there is mineral oil between the photocurable layers L2 of quartz glass plate 230 and second, photo-sensitive hydrogel can ooze
Enter between the photocurable layers L2 of quartz glass plate 230 and second.Or, photo-sensitive hydrogel is via the first photocurable layers L1 and second
The connected pore channel that pattern in photocurable layers L2 is formed enters between the photocurable layers L2 of quartz glass plate 230 and second.In quartz
Photo-sensitive hydrogel intermediate layer is formed between the photocurable layers L2 of sheet glass 230 and second.
In the 3rd moving step, lowering or hoisting gear 260 moves down platform 210 so that the focal plane of projecting lens 180 is located at light
The inside in quick hydrogel intermediate layer, is located exactly at the position of the lower section of quartz glass plate 230.
In the 3rd step of exposure, shutter 120 is opened to recover light path.UV light reaches DMD 160.Computer control unit
The view data of the 3rd sectional slice is supplied to DMD 160 by 300, controls the micro mirror array unit corresponding with each pixel
On off state, so as to form the mask graph consistent with sectional slice image.Under the irradiation of UV light, photo-sensitive hydrogel layer 250
It is corresponding with the focal plane of projecting lens 180 partially cured, and form the solidified portion corresponding with the mask graph of DMD 160
Point, so that the threeth photocurable layers L3 consistent with the 3rd sectional slice image is obtained, as shown in Figure 3 c.
In photo-sensitive hydrogel layer 250, by controlling the photo-sensitive hydrogel injection rate of each implantation step, after can causing
The photocurable layers of one aspect are attached on the surface of the photocurable layers of previous aspect.
In the method for the embodiment, quartz glass plate 230 is moved with the injection of photo-sensitive hydrogel, quartz glass plate
230 successively increase with the distance between the upper surface of platform 210.In photocuring print procedure, platform 210 is successively moved down, made
In the focal plane of projecting lens 180 in each step of exposure is always positioned at photo-sensitive hydrogel, and quartzy glass must be located exactly at
The position of the lower section of glass piece 230.The method successively forms the sectional slice image of every aspect from bottom to up, it is possible to by multiple
Photocurable layers constitute 3D printing object.
The 3D printing object can include complicated shape, such as, comprising hole, pipeline etc., life is formed such that it is able to be used for
Thing tissue.For the sectional slice imaging of each aspect, a thin layer exposure can be completed within every 10 seconds or so.Even if by repeatedly exposure
Light forms the 3D printing object for including multiple sectional slices, it is also possible to be quickly completed.
Fig. 4 a to 4c show the schematic diagram of each step of photocuring Method of printing according to the second embodiment of the present invention.
The photocuring Method of printing includes implantation step, to form photo-sensitive hydrogel layer 230 and then multiple alternate
Step of exposure and moving step, successively form the sectional slice image of every aspect in photo-sensitive hydrogel layer 250.As showing
Example, shows to form three embodiments of the sectional slice image of aspect in Fig. 4 a to 4c.
In implantation step, shutter 120 closes to cut off light path.Injecting controller 280 causes that injection propulsion plant 281 is moved
Make, photo-sensitive hydrogel is injected via injection channel 240, the photo-sensitive hydrogel layer of suitable thickness is formed in the upper surface of platform 210
250。
In the first moving step, shutter 120 closes to cut off light path.Lowering or hoisting gear 260 moves up and down platform 210, makes
The focal plane for obtaining projecting lens 180 is located at the inside of photo-sensitive hydrogel layer 250, is located exactly above the upper surface of platform 210
Position.
In the first step of exposure, shutter 120 is opened to recover light path.UV light reaches DMD 160.Computer control unit
The view data of the first sectional slice is supplied to DMD 160 by 300, controls the micro mirror array unit corresponding with each pixel
On off state, so as to form the mask graph consistent with sectional slice image.Under the irradiation of UV light, photo-sensitive hydrogel layer 250
It is corresponding with the focal plane of projecting lens 180 partially cured, and form the solidified portion corresponding with the mask graph of DMD 160
Point, so that the first photocurable layers L1 consistent with the first sectional slice image is obtained, as shown in fig. 4 a.
In the second moving step, shutter 120 closes to cut off light path.Lowering or hoisting gear 260 moves down platform 210 so that throw
The focal plane of shadow lens 180 is located at the inside of photo-sensitive hydrogel layer 250, is located exactly at the position of the top of the first photocurable layers L1
Put.
In the second step of exposure, shutter 120 is opened to recover light path.UV light reaches DMD 160.Computer control unit
The view data of the second sectional slice is supplied to DMD 160 by 300, controls the micro mirror array unit corresponding with each pixel
On off state, so as to form the mask graph consistent with sectional slice image.Under the irradiation of UV light, photo-sensitive hydrogel layer 250
It is corresponding with the focal plane of projecting lens 180 partially cured, and form the solidified portion corresponding with the mask graph of DMD 160
Point, so that the second photocurable layers L2 consistent with the second sectional slice image is obtained, as shown in Figure 4 b.
In the 3rd moving step, shutter 120 closes to cut off light path.Lowering or hoisting gear 260 moves down platform 210 so that throw
The focal plane of shadow lens 180 is located at the inside of photo-sensitive hydrogel layer 250, is located exactly at the position of the top of the second photocurable layers L2
Put.
In the 3rd step of exposure, shutter 120 is opened to recover light path.UV light reaches DMD 160.Computer control unit
The view data of the 3rd sectional slice is supplied to DMD 160 by 300, controls the micro mirror array unit corresponding with each pixel
On off state, so as to form the mask graph consistent with sectional slice image.Under the irradiation of UV light, photo-sensitive hydrogel layer 250
It is corresponding with the focal plane of projecting lens 180 partially cured, and form the solidification corresponding with the mask graph of DMD 160
Part, so that the threeth photocurable layers L3 consistent with the 3rd sectional slice image is obtained, as illustrated in fig. 4 c.
In photo-sensitive hydrogel layer 250, by controlling the displacement of each moving step, latter aspect can be caused
Photocurable layers are attached on the surface of the photocurable layers of previous aspect.
In the method for the embodiment, before the photocuring of every aspect, photo-sensitive hydrogel, quartzy glass are disposably injected
The distance between glass piece 230 and upper surface of platform 210 keep constant.
In photocuring print procedure, platform 210 is successively moved down so that the projecting lens 180 in each step of exposure
Focal plane is always positioned in photo-sensitive hydrogel, and is located exactly at the position above the photocurable layers of previous aspect.The method from
Under it is supreme successively formed every aspect sectional slice image, it is possible to constitute 3D printing object by multiple photocurable layers.
Fig. 5 a to 5c show the schematic diagram of each step of photocuring Method of printing according to the third embodiment of the invention.
The photocuring Method of printing includes multiple alternate implantation steps and step of exposure, in photo-sensitive hydrogel layer 250
Successively form the sectional slice image of every aspect.As an example, showing that the tomography to form three aspects is cut in Fig. 5 a to 5c
The embodiment of picture.
In this embodiment, in the coated one layer of mineral oil (being not shown) in the upper surface of platform 210.The mineral oil ensures
Together with will not being solidified to hydrogel above on platform 210, between preventing the photocurable layers that will be formed and platform 210
Bonding.In alternate embodiments, hydrophobic treatment can be carried out to the upper surface of platform 210, due to foring hydrophobic surface
Thus coated mineral oil is not needed.
Before photocuring printing, the position of platform 210 is pre-set so that the focal plane of projecting lens 180 is located at flat
The correct position of the surface of platform 210.In subsequent photocuring print procedure, keep the position of platform 210 constant.
In the first implantation step, shutter 120 closes to cut off light path.Injecting controller 280 causes injection propulsion plant
281 actions, photo-sensitive hydrogel is injected via injection channel 240, and the photosensitive water-setting of suitable thickness is formed in the upper surface of platform 210
Glue-line 250.The focal plane of projecting lens 180 is located at the inside of photo-sensitive hydrogel layer 250, is located exactly at the surface of platform 210
Position.
In the first step of exposure, shutter 120 is opened to recover light path.UV light reaches DMD 160.Computer control unit
The view data of the first sectional slice is supplied to DMD 160 by 300, controls the micro mirror array unit corresponding with each pixel
On off state, so as to form the mask graph consistent with sectional slice image.Under the irradiation of UV light, photo-sensitive hydrogel layer
250 is corresponding with the focal plane of projecting lens 180 partially cured, and forms corresponding with the mask graph of DMD 160 consolidating
Change part, so that the first photocurable layers L1 consistent with the first sectional slice image is obtained, as shown in Figure 5 a.
In the second implantation step, shutter 120 closes to cut off light path.Injecting controller 280 causes injection propulsion plant
281 actions, photo-sensitive hydrogel is injected via injection channel 240, so that the thickness of photo-sensitive hydrogel layer 250 increases.
Due to there is mineral oil between the photocurable layers L1 of platform 210 and first, photo-sensitive hydrogel can penetrate into platform
210 and first between photocurable layers L1.Or, the intercommunicating pore that photo-sensitive hydrogel is formed via the pattern in the first photocurable layers L1
Road enters between the photocurable layers L1 of platform 210 and first.Photo-sensitive hydrogel is formed between the photocurable layers L1 of platform 210 and first
Intermediate layer.
In the second step of exposure, shutter 120 is opened to recover light path.UV light reaches DMD 160.Computer control unit
The view data of the second sectional slice is supplied to DMD 160 by 300, controls the micro mirror array unit corresponding with each pixel
On off state, so as to form the mask graph consistent with sectional slice image.Under the irradiation of UV light, photo-sensitive hydrogel layer 250
It is corresponding with the focal plane of projecting lens 180 partially cured, and form the solidified portion corresponding with the mask graph of DMD 160
Point, so that the second photocurable layers L2 consistent with the second sectional slice image is obtained, as shown in Figure 5 b.
In the 3rd implantation step, shutter 120 closes to cut off light path.Injecting controller 280 causes injection propulsion plant
281 actions, photo-sensitive hydrogel is injected via injection channel 240, so that the thickness of photo-sensitive hydrogel layer 250 increases.
Due to there is mineral oil between the photocurable layers L2 of platform 210 and second, photo-sensitive hydrogel can penetrate into platform
210 and second between photocurable layers L2.Or, photo-sensitive hydrogel is via in the first photocurable layers L1, the second photocurable layers L2
The connected pore channel that pattern is formed enters between the photocurable layers L2 of platform 210 and second.The photocurable layers L2 of platform 210 and second it
Between form photo-sensitive hydrogel intermediate layer.
In the 3rd step of exposure, shutter 120 is opened to recover light path.UV light reaches DMD 160.Computer control unit
The view data of the 3rd sectional slice is supplied to DMD 160 by 300, controls the micro mirror array unit corresponding with each pixel
On off state, so as to form the mask graph consistent with sectional slice image.Under the irradiation of UV light, photo-sensitive hydrogel layer 250
It is corresponding with the focal plane of projecting lens 180 partially cured, and form the solidified portion corresponding with the mask graph of DMD 160
Point, so that the threeth photocurable layers L3 consistent with the 3rd sectional slice image is obtained, as shown in Figure 5 c.
In photo-sensitive hydrogel layer 250, by controlling the photo-sensitive hydrogel injection rate of each implantation step, after can causing
The photocurable layers of one aspect are attached on the surface of the photocurable layers of previous aspect.
In the method for the embodiment, pre-set the position of platform 210 and kept not in photocuring print procedure
Become so that the focal plane of projecting lens 180 is always positioned at the position above the upper surface of platform 210.
In photocuring print procedure, quartz glass plate 230 is moved with the injection of photo-sensitive hydrogel, quartz glass plate
230 successively increase with the distance between the upper surface of platform 210.The focal plane of projecting lens 180 is begun in each step of exposure
Final position is located exactly at the position above the upper surface of platform 210 in photo-sensitive hydrogel.The method is successively formed from top to bottom
The sectional slice image of every aspect, it is possible to constitute 3D printing object by multiple photocurable layers.
According to embodiments of the invention as described above, these embodiments do not have all of details of detailed descriptionthe, not yet
It is only described specific embodiment to limit the invention.Obviously, as described above, can make many modifications and variations.This explanation
Book is chosen and specifically describes these embodiments, is in order to preferably explain principle of the invention and practical application, so that affiliated
Technical field technical staff can be used using modification of the invention and on the basis of the present invention well.Protection model of the invention
The scope that enclosing should be defined by the claims in the present invention is defined.
Claims (22)
1. a kind of photocuring printing device, three-dimensional structure is formed for the image according to Computer Storage in photo-sensitive hydrogel,
Including：
Digital projection unit, for by image projection to photo-sensitive hydrogel layer；
Photo-sensitive hydrogel solidified cell, for providing photo-sensitive hydrogel to form photo-sensitive hydrogel layer, and according to the figure of projection
As successively solidifying in photo-sensitive hydrogel layer；And
Computer control unit, for providing the image of image and control projection in photo-sensitive hydrogel layer to digital projection unit
In image space,
Wherein, the photo-sensitive hydrogel solidified cell is including guide rod and is arranged along the carrying tablet that guide rod is moved, described to hold
The lower surface of slide glass limits the upper liquid level of photo-sensitive hydrogel layer,
The photo-sensitive hydrogel solidified cell includes platform, and the upper surface of the platform supports photo-sensitive hydrogel layer,
The carrying tablet and the platform limit photo-sensitive hydrogel layer together.
2. photocuring printing device according to claim 1, wherein, the digital projection unit includes：
DMD, including multiple micro mirrors composition array and according to described image set micro mirror on off state；
Total reflection prism, for the directional light produced from light source to be reflexed into DMD；And
Projecting lens, for the reflected light projects of the micro mirror of open state will to be in in photo-sensitive hydrogel layer, so as to saturating in projection
The focal plane position imaging of mirror.
3. photocuring printing device according to claim 2, wherein, the digital projection unit also includes shutter, is used for
Control command cut-out or recovery light path according to computer control unit.
4. photocuring printing device according to claim 2, wherein the photo-sensitive hydrogel solidified cell also includes：
Injection channel, is arranged on platform interior, the upper surface for photo-sensitive hydrogel to be delivered to platform；
Lowering or hoisting gear, the upper level for adjusting platform；
Ascending pipe, for accommodating photo-sensitive hydrogel and being connected with injection channel；
Injection propulsion plant, for the photo-sensitive hydrogel in ascending pipe to be advanced into injection channel；And
Injecting controller, the action for controlling injection propulsion plant, so as to control injection rate.
5. photocuring printing device according to claim 1, wherein the carrying tablet is quartz glass plate.
6. photocuring printing device according to claim 1, wherein the lower surface of the carrying tablet is by hydrophobic treatment, from
And obtain hydrophobic surface.
7. photocuring printing device according to claim 1, wherein the coated mineral oil of the lower surface of the carrying tablet.
8. photocuring printing device according to claim 4, wherein the upper surface of the platform is by hydrophobic treatment, so that
Obtain hydrophobic surface.
9. photocuring printing device according to claim 4, wherein the coated mineral oil in the upper surface of the platform.
10. photocuring printing device according to claim 1, wherein described image are the sectional slice figure of three-dimensional structure
Picture.
A kind of 11. photocuring Method of printings, three-dimensional structure is formed for the image according to Computer Storage in photo-sensitive hydrogel,
Including：
Implantation step, forms photo-sensitive hydrogel layer between platform and carrying tablet, and photosensitive water is limited using the lower surface of carrying tablet
The upper liquid level of gel layer, and using the upper surface support photo-sensitive hydrogel layer of platform, the carrying tablet and the platform are together
Limit photo-sensitive hydrogel layer；
Step of exposure, the imaging surface in photo-sensitive hydrogel layer produces projected image so that the appropriate section of photo-sensitive hydrogel layer
Solidification.
12. photocuring Method of printings according to claim 11, wherein the imaging surface is the focal plane of projecting lens.
13. photocuring Method of printings according to claim 11, wherein before implantation step, also including to carrying tablet
At least one upper surface of lower surface and platform carries out hydrophobic treatment, to prevent photocurable layers to be bonded thereon.
14. photocuring Method of printings according to claim 11, wherein before implantation step, being additionally included in carrying tablet
The upper coated mineral oil at least one upper surface of lower surface and platform, to prevent photocurable layers to be bonded thereon.
15. photocuring Method of printings according to claim 11, in implantation step the upper surface of carrying tablet and platform it
Between distance change with injection rate, the movement of carrying tablet is limited by guide rod, vertical relative to imaging surface so as to be only capable of
It is mobile.
16. photocuring Method of printings according to claim 11, wherein between implantation step and step of exposure, also including
Moving step, wherein the mobile platform in the moving step so that carrying tablet remains predetermined relative to the distance of imaging surface
Value.
17. photocuring Method of printings according to claim 16, wherein being repeatedly injected step, moving step and exposure step
Suddenly, since the lower surface of carrying tablet, the every aspect of three-dimensional structure is successively formed from bottom to up.
18. photocuring Method of printings according to claim 11, after the implant step, also including moving step, wherein
The mobile platform in the moving step so that imaging surface is located at the upper surface top of the photocurable layers of previous aspect, and phase
Distance for the photocurable layers of previous aspect keeps predetermined value.
19. photocuring Method of printings according to claim 18, wherein repeatedly moving step and step of exposure, from platform
Upper surface starts, and the every aspect of three-dimensional structure is successively formed from bottom to up.
20. photocuring Method of printings according to claim 11, wherein pre-setting the position of platform and in photocuring
Kept in print procedure constant so that imaging surface is always positioned at the position above the upper surface of platform.
21. photocuring Method of printings according to claim 20, wherein being repeatedly injected step and step of exposure so that in note
Enter in step, the intermediate layer of photo-sensitive hydrogel, and imaging surface position are formed between the upper surface of platform and photocurable layers
In intermediate layer.
22. photocuring Method of printings according to claim 21, wherein step and step of exposure are repeatedly injected, from platform
Upper surface starts, and the every aspect of three-dimensional structure is successively formed from top to bottom.
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| CN106313542A (en) * | 2015-06-17 | 2017-01-11 | 成都金采科技有限公司 | 3D printer |
| WO2017018938A1 (en) * | 2015-07-27 | 2017-02-02 | Agency For Science, Technology And Research | A multi-modal printing system and method of operating the same |
| WO2017049519A1 (en) * | 2015-09-24 | 2017-03-30 | 北京大学口腔医院 | Three-dimensional printer, and three-dimensional printing method and device |
| WO2017147434A1 (en) | 2016-02-26 | 2017-08-31 | Trio Labs, Inc. | Method and apparatus for solid freeform fabrication of objects utilizing in situ in fusion |
| TW201804269A (en) * | 2016-07-28 | 2018-02-01 | 禾鈶股份有限公司 | System of additive manufacturing using holographic projection and method thereof |
| CN109507768A (en) * | 2018-11-29 | 2019-03-22 | 交通运输部公路科学研究所 | Minute yardstick optical texture processing unit (plant) |
| CN111619108A (en) * | 2019-02-28 | 2020-09-04 | 宁波市石生科技有限公司 | Novel photocuring 3D printing apparatus |
| CN110228193B (en) * | 2019-06-04 | 2021-10-15 | 浙江大学 | Integrated colored light 3D biological printing system based on imaging principle |
| WO2020244037A1 (en) * | 2019-06-04 | 2020-12-10 | 浙江大学 | Imaging principle-based integrated color light 3d bioprinting system |
| CN112810148A (en) * | 2019-11-18 | 2021-05-18 | 深圳市绎立锐光科技开发有限公司 | 3D printing system |
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| CN104085106A (en) * | 2014-01-21 | 2014-10-08 | 上海坤融实业有限公司 | DLP principle based 3D printer |
| CN104093547B (en) * | 2014-05-26 | 2016-11-16 | 中国科学院自动化研究所 | 3D print system |
| CN204095140U (en) * | 2014-08-06 | 2015-01-14 | 浙江闪铸三维科技有限公司 | A kind of 3D printer based on DLP technology |
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