CN104587388A - Pharmaceutical composition for treating knee arthritis through external application and preparation method thereof - Google Patents
Pharmaceutical composition for treating knee arthritis through external application and preparation method thereof Download PDFInfo
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- CN104587388A CN104587388A CN201510009152.2A CN201510009152A CN104587388A CN 104587388 A CN104587388 A CN 104587388A CN 201510009152 A CN201510009152 A CN 201510009152A CN 104587388 A CN104587388 A CN 104587388A
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Abstract
The invention discloses a pharmaceutical composition for treating knee arthritis through external application. The pharmaceutical composition comprises the following raw materials in parts by weight: 13-17 parts of musk, 10-14 parts of radix aconiti, 13-17 parts of Radix Aconiti Kusenzoffii, 9-11 parts of clove, 13-17 parts of radix angelicae, 13-17 parts of frankincense, 13-17 parts of myrrh, 25-35 parts of Divaricate Saposhniovia Root, 18-22 parts of turmeric, 9-11 parts of borneol, 13-17 parts of safflower, 13-17 parts of mint, 13-17 parts of notopterygium root and 10-14 parts of dragon's blood. The invention also discloses a method for preparing the pharmaceutical composition for treating knee arthritis through external application. The pharmaceutical composition treats both symptoms and root causes aiming at the etiology and pathogenesis of the knee arthritis, and the total effective rate can be 98 percent.
Description
Technical field
The present invention relates to technical field of Chinese medicines, particularly relate to pharmaceutical composition of a kind of external application for curing gonarthritis and preparation method thereof.
Background technology
Gonarthritis is kneed common disease, and common arthritis can be divided into three types: 1, osteoarthritis: modal arthritis, is commonly considered as chronic progressive external degenerative disorders.With the chronic wearing and tearing of cartilage for feature.The person in middle and old age that are everlasting fall ill, and at the initial stage of disease, do not have obvious symptom, or symptom are slight.The early stage stiff sense of discomfort often showing as joint, takes a turn for the better after movable.Meet aggravating activities and can occur that acute inflammation shows, have a rest and alleviate after symptomatic treatment; 2, post-traumatic arthritis: the arthritis engendered after knee joint trauma.Clinical manifestation is close with osteoarthritis, but has clear and definite trauma history, as: through the fracture in joint, ligament injury or meniscus injury; 3, rheumatoid arthritis: arthritic struvite type, in early days based on the synovial membrane inflammation in joint, then corrode articular cartilage, cause the serious loss of function of joint, the clinical stage of late osteoarthritis remains severe deformities.Rheumatoid arthritis can occur in any age, in the majority with youngster, usually involves two knee joint.
Gonarthritis belongs to the category of the traditional Chinese medical science " rheumatism involving the bone ".Pathogenesis belongs to that strain cold is attacked, wet poly-blood clotting, phlegm and blood stasis, the blood vessels stasis of blood are stagnant, qi depression to blood stasis, impatency meridians, stagnation of QI and blood may bring about pain, then swollen, joint stuffiness.Pathogeny is summarised as constitutional and suffers from a deficiency of the kidney and Secondary cases blood stasis.And primary disease sickness rate is very high, modern medicine can carry out joint replacement surgery, but most people is not for accepting and cannot bear the huge cost of operation.Chinese medicine and western medicine is at present without the method for radically treating, and medicine mostly is oral medicine, and cause damage to Liver and kidney while stimulation stomach, intestinal, toxic and side effects is larger.
Summary of the invention
Based on the technical problem that background technology exists, the present invention proposes pharmaceutical composition of a kind of external application for curing gonarthritis and preparation method thereof, for the etiology and pathogenesis of gonarthritis, treating both the principal and secondary aspects of a disease, total effective rate can reach 98%.
The pharmaceutical composition of a kind of external application for curing gonarthritis that the present invention proposes, its raw material comprises by weight: Moschus 13-17 part, Radix Aconiti Kusnezoffii 10-14 part, Radix Aconiti 13-17 part, Flos Caryophylli 9-11 part, Radix Angelicae Dahuricae 13-17 part, Olibanum 13-17 part, Myrrha 13-17 part, RADIX SAPOSHINOKOVIAE from Northeast 25-35 part, Rhizoma Curcumae Longae 18-22 part, Borneolum Syntheticum 9-11 part, Flos Carthami 13-17 part, Mentholum 13-17 part, Rhizoma Et Radix Notopterygii 13-17 part, Sanguis Draxonis 10-14 part.
Moschus, is the secretions of the glandular sac between the umbilicus of male Moschus moschiferous and genitals, in graininess or bulk after dry, have special fragrance, have bitterness, can make spice, also can be used as medicine.Acrid in the mouth, warm in nature, GUIXIN, spleen channel.There is refreshment of having one's ideas straightened out, promoting blood circulation to restore menstrual flow, pain relieving, the effect of hastening parturition.For excess syndrome of stroke coma, sore swollen toxin, laryngopharynx swelling and pain, blood stasis amenorrhea, note of the ancient Chinese abdominal mass, trusted subordinate's sudden pain, traumatic injury, the cards such as anemofrigid-damp arthralgia.
Radix Aconiti Kusnezoffii is the tuber of ranunculaceae plant Aconitum kusnezoffii Reichb.Autumn excavates, and removes residual stem, fibrous root and earth, cleaning, drying.Acrid in the mouth, hardship, hot in nature; Poisonous.GUIXIN, liver,kidney,spleen warp.Energy expelling wind and removing dampness, antalgic.For anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.
Radix Aconiti is the parent root of ranunculaceae plant Ka Shi Aconitum carmichjaelii Debx..Late June excavated to early August, and removing daughter root, fibrous root and silt, dry.Acrid in the mouth, hardship, hot in nature; Poisonous.GUIXIN, liver,kidney,spleen warp.Energy expelling wind and removing dampness, antalgic.For anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.Raw product are for oral administration should be careful.Should not with Bulbus Fritillariae Uninbracteatae, the Rhizoma Pinelliae, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Ampelopsis, Radix Trichosanthis, Fructus Trichosanthis with using.
Flos Caryophylli is alabastrum or the fruit of Myrtaceae arbor Flos Caryophylli.Acrid in the mouth, warm in nature, return lung, stomach, spleen, kidney channel.There is sending down the abnormal ascending QI only oh, warming spleen and stomach for dispelling cold pain relieving, effect of warming the kidney to activate YANG.For singultus, vomiting, epigastric pain, insufficiency of kidney-YANG, sexual impotence, flaccidity of the lower limbs and the inferior disease of cold-damp band.
The Radix Angelicae Dahuricae is the root of the samphire Radix Angelicae Dahuricae or angelica anomala.Acrid in the mouth, warm in nature; Return lung, stomach, large intestine channel; Fragrance rises loose; There is expelling pathogenic wind from the body surface, dispersing cold for relieving pain, dehumidify sensible, effect of detumescence and apocenosis; Cure mainly anemofrigid cold, headache, supraorbital bone pain, toothache, eye itching lacrimation, nasal obstruction, nasal sinusitis, wet Sheng chronic diarrhea, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, pruritus scabies, venom.
Olibanum is Burseraceae short and small arbor B.carteri gum resin.Acrid in the mouth, hardship, warm in nature.GUIXIN, liver, spleen channel.There is promoting blood circulation and stopping pain, effect of detumescence and promoting granulation.For epigastric pain, rheumatic arthralgia ， Die Pu is grieved, abdominal pain during menstruation, and skin infection swells and ache, and the disease such as do not close up after bursting for a long time.
Myrrha is the gum resin of olive subject plant myrrh or Alan fort myrrh.Bitter in the mouth, property is put down.GUIXIN, liver, spleen channel.There is loose blood blood stasis removing, effect of subduing swelling and relieving pain.Cure mainly traumatic injury, incised wound, muscles and bones, all pains of trusted subordinate, lump in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye
RADIX SAPOSHINOKOVIAE from Northeast, also known as other wind, Radix Saposhnikoviae, is Umbelliferae herbaceos perennial.Be used as medicine with dry root, main product in Heilungkiang, Liaoning, Jilin.The Radix Saposhnikoviae quality originating in three provinces in the northeast of China is best, and claim RADIX SAPOSHINOKOVIAE from Northeast, quality is best.Acrid in the mouth, sweet, slightly warm in nature.Return bladder, liver, spleen channel.There is expelling pathogenic wind from the body surface, removing dampness to relieve pain, effect of relieving convulsion.Cure mainly diseases caused by exogenous pathogenic factor exterior syndrome, rubella pruritus, rheumatic arthralgia, tetanus.
Rhizoma Curcumae Longae is the rhizome of Zingiberaceae herbaceous plant Rhizoma Curcumae Longae.Bitter in the mouth, pungent, warm in nature.Return spleen, Liver Channel.Can invigorate blood circulation, circulation of qi promoting, pain relieving, to dispel the wind, wet profit, eliminating impediment.For pain in chest and hypochondrium, amenorrhea is suffered from abdominal pain, the diseases such as rheumatic arthralgia.
Borneolum Syntheticum, for the process of resin product of Spore density Borneolum Syntheticum, also useful feverfew Herba Blumeae Balsamiferae (great Ai) leaf cools the crystallization product (being called Blumeae preparatum Tabellae) of gained after distillation, and with the Synthetic artifact (title BORNEOLUM SYNTHETICUM) that Lignum Pini Nodi wet goods is made.Acrid in the mouth, hardship, cold nature.Enter the heart, spleen, lung meridian.Can analepsia have one's ideas straightened out, clearing away heat to alleviate pain.Faint for coma convulsion, skin infection scabies, aphtha, the diseases such as laryngalgia and ophthalmic.
Flos Carthami is the tubular inflorescence of Compositae herbal plant Flos Carthami.Acrid in the mouth, warm in nature.Return liver, heart channel.There is the effect of blood circulation promoting and blood stasis dispelling; For lump in the abdomen caking, sore, carbuncle and painful swelling, tumbling down is grieved, rheumatic arthralgia, menoxenia, and amenorrhea is suffered from abdominal pain, puerperal stasis of blood pain, macule color is dark, waits disease.
Mentholum is a kind of saturated cyclic alcohol obtained in peppermint.Have another name called menthol, Mentholum.Can be used as aromatic drug, remedium corrigens and carminative to use.Can be used for skin or mucosa to produce refrigerant sense and be not suitable for alleviate, cure mainly pain.
Rhizoma Et Radix Notopterygii is dry rhizome and the root of Umbelliferae herbaceos perennial Rhizoma Et Radix Notopterygii.Acrid in the mouth, hardship, warm in nature; Enter bladder, kidney channel; There is expelling pathogenic wind from the body surface, wind-damp dispelling, effect of pain relieving.For cold, fever with chills, rheumatic arthralgia, the diseases such as headache.
Sanguis Draxonis is the resin in babassu Sanguis Draxonis fruit and trunk.Sweet-salty, property is put down.There is promoting blood circulation to remove blood stasis, analgesic therapy, hemostasia and promoting granulation, effect of sore.Cure mainly treating swelling and pain by traumatic injury, ecchymoma due to internal injury; Continuous bleeding due to traumatic injury, scrofula, ecthyma unhealed for long time.Sanguis Draxonis joins Myrrha, and the power of its promoting blood circulation and breaking stagnation strengthens, for traumatic injury, and swelling and pain due to blood stasis; Sanguis Draxonis joins Olibanum, blood activating and promoting tissue regeneration, again sore, stretches muscle, therefore can be used for malignant boil carbuncle, and do not close up for a long time, incised wound is hemorrhage, and wound such as not to conform at the disease.
Preferably, the weight ratio of Radix Aconiti Kusnezoffii, Radix Aconiti, RADIX SAPOSHINOKOVIAE from Northeast and Rhizoma Curcumae Longae is 11-13:14-16:28-32:19-21.
Preferably, its raw material comprises by weight: Moschus 14-16 part, Radix Aconiti Kusnezoffii 11-13 part, Radix Aconiti 14-16 part, Flos Caryophylli 9.6-10.2 part, Radix Angelicae Dahuricae 14-16 part, Olibanum 14-16 part, Myrrha 14-16 part, RADIX SAPOSHINOKOVIAE from Northeast 28-32 part, Rhizoma Curcumae Longae 19-21 part, Borneolum Syntheticum 9.5-10.5 part, Flos Carthami 14-16 part, Mentholum 14-16 part, Rhizoma Et Radix Notopterygii 14-16 part, Sanguis Draxonis 11-13 part.
Preferably, the weight ratio of Moschus, the Radix Angelicae Dahuricae, Olibanum, Myrrha, Flos Carthami, Mentholum and Rhizoma Et Radix Notopterygii is 1:1:1:1:1:1:1.
Preferably, its raw material comprises by weight: 15 parts, Moschus, Radix Aconiti Kusnezoffii 12 parts, Radix Aconiti 15 parts, Flos Caryophylli 10 parts, the Radix Angelicae Dahuricae 15 parts, Olibanum 15 parts, Myrrha 15 parts, RADIX SAPOSHINOKOVIAE from Northeast 30 parts, 20 parts, Rhizoma Curcumae Longae, Borneolum Syntheticum 10 parts, 15 parts, Flos Carthami, Mentholum 15 parts, Rhizoma Et Radix Notopterygii 15 parts, Sanguis Draxonis 12 parts.
The pharmaceutical composition preparation method of a kind of above-mentioned external application for curing gonarthritis that the present invention also proposes, blended to Moschus, Radix Aconiti Kusnezoffii, Radix Aconiti, Flos Caryophylli, the Radix Angelicae Dahuricae, Olibanum, Myrrha, RADIX SAPOSHINOKOVIAE from Northeast, Rhizoma Curcumae Longae, Borneolum Syntheticum, Flos Carthami, Mentholum, Rhizoma Et Radix Notopterygii and Sanguis Draxonis rear pulverizing is obtained mixed material, then adds yellow wine and be stirred to the pharmaceutical composition that pasty state obtains external application for curing gonarthritis.
The present invention is directed to the etiology and pathogenesis of gonarthritis, with RADIX SAPOSHINOKOVIAE from Northeast and Rhizoma Curcumae Longae for monarch drug, can invigorate blood circulation, circulation of qi promoting, pain relieving, to dispel the wind, dampness removing, eliminating impediment; With Moschus, the Radix Angelicae Dahuricae, Olibanum, Myrrha, Flos Carthami, Rhizoma Et Radix Notopterygii, Sanguis Draxonis for ministerial drug, can promoting blood circulation and breaking stagnation, inducing menstruation to relieve menalgia, detumescence and apocenosis, dispelling cold and removing dampness, expelling pathogenic wind from the body surface, and with Radix Aconiti Kusnezoffii, Radix Aconiti, Flos Caryophylli, Borneolum Syntheticum for adjuvant drug, strengthen the effect of expelling wind and removing dampness, antalgic, warming the kidney to activate YANG, waking up the patient from unconsciousness by clearing away heat; All medicine compatibilities share, and further increase the effect of promoting blood circulation and breaking stagnation, expelling wind and removing dampness, inducing menstruation to relieve menalgia.Mentholum act is drawn all medicines and is goed deep into intraarticular.All medicines are common to knee joint local, make the efficacy of a drug grand and directly enter disease institute, eliminating evil and just do not hinder.New wound is not produced to knee joint tissue in therapeutic process, therefore good result recent and at a specified future date can be obtained.The invention belongs to medicine for external use, have no side effect to human organ, drug safety is reliable.
Detailed description of the invention
Below, by specific embodiment, technical scheme of the present invention is described in detail.
Embodiment 1
The pharmaceutical composition of a kind of external application for curing gonarthritis that the present invention proposes, its raw material comprises by weight: 13 parts, Moschus, Radix Aconiti Kusnezoffii 14 parts, Radix Aconiti 13 parts, Flos Caryophylli 11 parts, the Radix Angelicae Dahuricae 13 parts, Olibanum 17 parts, Myrrha 13 parts, RADIX SAPOSHINOKOVIAE from Northeast 35 parts, 18 parts, Rhizoma Curcumae Longae, Borneolum Syntheticum 11 parts, 13 parts, Flos Carthami, Mentholum 17 parts, Rhizoma Et Radix Notopterygii 13 parts, Sanguis Draxonis 14 parts.
The pharmaceutical composition preparation method of a kind of above-mentioned external application for curing gonarthritis that the present invention also proposes, blended to Moschus, Radix Aconiti Kusnezoffii, Radix Aconiti, Flos Caryophylli, the Radix Angelicae Dahuricae, Olibanum, Myrrha, RADIX SAPOSHINOKOVIAE from Northeast, Rhizoma Curcumae Longae, Borneolum Syntheticum, Flos Carthami, Mentholum, Rhizoma Et Radix Notopterygii and Sanguis Draxonis rear pulverizing is obtained mixed material, then adds yellow wine and be stirred to the pharmaceutical composition that pasty state obtains external application for curing gonarthritis.
Embodiment 2
The pharmaceutical composition of a kind of external application for curing gonarthritis that the present invention proposes, its raw material comprises by weight: 14 parts, Moschus, Radix Aconiti Kusnezoffii 13 parts, Radix Aconiti 14 parts, Flos Caryophylli 10.2 parts, the Radix Angelicae Dahuricae 14 parts, Olibanum 16 parts, Myrrha 14 parts, RADIX SAPOSHINOKOVIAE from Northeast 32 parts, 19 parts, Rhizoma Curcumae Longae, Borneolum Syntheticum 10.5 parts, 14 parts, Flos Carthami, Mentholum 16 parts, Rhizoma Et Radix Notopterygii 14 parts, Sanguis Draxonis 13 parts.
The pharmaceutical composition preparation method of a kind of above-mentioned external application for curing gonarthritis that the present invention also proposes, blended to Moschus, Radix Aconiti Kusnezoffii, Radix Aconiti, Flos Caryophylli, the Radix Angelicae Dahuricae, Olibanum, Myrrha, RADIX SAPOSHINOKOVIAE from Northeast, Rhizoma Curcumae Longae, Borneolum Syntheticum, Flos Carthami, Mentholum, Rhizoma Et Radix Notopterygii and Sanguis Draxonis rear pulverizing is obtained mixed material, then adds yellow wine and be stirred to the pharmaceutical composition that pasty state obtains external application for curing gonarthritis.
Embodiment 3
The pharmaceutical composition of a kind of external application for curing gonarthritis that the present invention proposes, its raw material comprises by weight: 16 parts, Moschus, Radix Aconiti Kusnezoffii 11 parts, Radix Aconiti 16 parts, Flos Caryophylli 9.6 parts, the Radix Angelicae Dahuricae 16 parts, Olibanum 14 parts, Myrrha 16 parts, RADIX SAPOSHINOKOVIAE from Northeast 28 parts, 21 parts, Rhizoma Curcumae Longae, Borneolum Syntheticum 9.5 parts, 16 parts, Flos Carthami, Mentholum 14 parts, Rhizoma Et Radix Notopterygii 16 parts, Sanguis Draxonis 11 parts.
The pharmaceutical composition preparation method of a kind of above-mentioned external application for curing gonarthritis that the present invention also proposes, blended to Moschus, Radix Aconiti Kusnezoffii, Radix Aconiti, Flos Caryophylli, the Radix Angelicae Dahuricae, Olibanum, Myrrha, RADIX SAPOSHINOKOVIAE from Northeast, Rhizoma Curcumae Longae, Borneolum Syntheticum, Flos Carthami, Mentholum, Rhizoma Et Radix Notopterygii and Sanguis Draxonis rear pulverizing is obtained mixed material, then adds yellow wine and be stirred to the pharmaceutical composition that pasty state obtains external application for curing gonarthritis.
Embodiment 4
The pharmaceutical composition of a kind of external application for curing gonarthritis that the present invention proposes, its raw material comprises by weight: 17 parts, Moschus, Radix Aconiti Kusnezoffii 10 parts, Radix Aconiti 17 parts, Flos Caryophylli 9 parts, the Radix Angelicae Dahuricae 17 parts, Olibanum 13 parts, Myrrha 17 parts, RADIX SAPOSHINOKOVIAE from Northeast 25 parts, 22 parts, Rhizoma Curcumae Longae, Borneolum Syntheticum 9 parts, 17 parts, Flos Carthami, Mentholum 13 parts, Rhizoma Et Radix Notopterygii 17 parts, Sanguis Draxonis 10 parts.
The pharmaceutical composition preparation method of a kind of above-mentioned external application for curing gonarthritis that the present invention also proposes, blended to Moschus, Radix Aconiti Kusnezoffii, Radix Aconiti, Flos Caryophylli, the Radix Angelicae Dahuricae, Olibanum, Myrrha, RADIX SAPOSHINOKOVIAE from Northeast, Rhizoma Curcumae Longae, Borneolum Syntheticum, Flos Carthami, Mentholum, Rhizoma Et Radix Notopterygii and Sanguis Draxonis rear pulverizing is obtained mixed material, then adds yellow wine and be stirred to the pharmaceutical composition that pasty state obtains external application for curing gonarthritis.
Embodiment 5
The pharmaceutical composition of a kind of external application for curing gonarthritis that the present invention proposes, its raw material comprises by weight: 15 parts, Moschus, Radix Aconiti Kusnezoffii 12 parts, Radix Aconiti 15 parts, Flos Caryophylli 10 parts, the Radix Angelicae Dahuricae 15 parts, Olibanum 15 parts, Myrrha 15 parts, RADIX SAPOSHINOKOVIAE from Northeast 30 parts, 20 parts, Rhizoma Curcumae Longae, Borneolum Syntheticum 10 parts, 15 parts, Flos Carthami, Mentholum 15 parts, Rhizoma Et Radix Notopterygii 15 parts, Sanguis Draxonis 12 parts.
The pharmaceutical composition preparation method of a kind of above-mentioned external application for curing gonarthritis that the present invention also proposes, blended to Moschus, Radix Aconiti Kusnezoffii, Radix Aconiti, Flos Caryophylli, the Radix Angelicae Dahuricae, Olibanum, Myrrha, RADIX SAPOSHINOKOVIAE from Northeast, Rhizoma Curcumae Longae, Borneolum Syntheticum, Flos Carthami, Mentholum, Rhizoma Et Radix Notopterygii and Sanguis Draxonis rear pulverizing is obtained mixed material, then adds yellow wine and be stirred to the pharmaceutical composition that pasty state obtains external application for curing gonarthritis.
Embodiment 6
The pharmaceutical composition of a kind of external application for curing gonarthritis that the present invention proposes, its raw material comprises by weight: Moschus 15g, Radix Aconiti Kusnezoffii 12g, Radix Aconiti 15g, Flos Caryophylli 10g, Radix Angelicae Dahuricae 15g, Olibanum 15g, Myrrha 15g, RADIX SAPOSHINOKOVIAE from Northeast 30g, Rhizoma Curcumae Longae 20g, Borneolum Syntheticum 10g, Flos Carthami 15g, Mentholum 15g, Rhizoma Et Radix Notopterygii 15g, Sanguis Draxonis 12g.
The pharmaceutical composition preparation method of a kind of above-mentioned external application for curing gonarthritis that the present invention also proposes, blended to Moschus, Radix Aconiti Kusnezoffii, Radix Aconiti, Flos Caryophylli, the Radix Angelicae Dahuricae, Olibanum, Myrrha, RADIX SAPOSHINOKOVIAE from Northeast, Rhizoma Curcumae Longae, Borneolum Syntheticum, Flos Carthami, Mentholum, Rhizoma Et Radix Notopterygii and Sanguis Draxonis rear pulverizing is obtained mixed material, then adds yellow wine and be stirred to the pharmaceutical composition that pasty state obtains external application for curing gonarthritis.
Choose 100 patients being diagnosed as gonarthritis, pharmaceutical composition embodiment 6 obtained wraps up, for external application knee joint place with spinning cloth, the pharmaceutical composition at every turn prepared uses 3-5 time, and the course for the treatment of continues half a year, recovery from illness 87 example, effective person 11 example, nonresponder 2 example, total effective rate is 98%.
Wherein, efficacy assessment standard is: recovery from illness: knee joint swelling, pain disappear substantially, and joint movement function recovers normal; Effective: knee joint swelling pain obviously alleviates, and joint movement function is normal; Effective: knee joint swelling pain alleviates, joint movement function part is recovered; Invalid: clinical symptoms and function of joint are not improved before comparatively treating.
The above; be only the present invention's preferably detailed description of the invention; but protection scope of the present invention is not limited thereto; anyly be familiar with those skilled in the art in the technical scope that the present invention discloses; be equal to according to technical scheme of the present invention and inventive concept thereof and replace or change, all should be encompassed within protection scope of the present invention.
Claims (6)
1. a pharmaceutical composition for external application for curing gonarthritis, is characterized in that, its raw material comprises by weight: Moschus 13-17 part, Radix Aconiti Kusnezoffii 10-14 part, Radix Aconiti 13-17 part, Flos Caryophylli 9-11 part, Radix Angelicae Dahuricae 13-17 part, Olibanum 13-17 part, Myrrha 13-17 part, RADIX SAPOSHINOKOVIAE from Northeast 25-35 part, Rhizoma Curcumae Longae 18-22 part, Borneolum Syntheticum 9-11 part, Flos Carthami 13-17 part, Mentholum 13-17 part, Rhizoma Et Radix Notopterygii 13-17 part, Sanguis Draxonis 10-14 part.
2. the pharmaceutical composition of external application for curing gonarthritis according to claim 1, is characterized in that, the weight ratio of Radix Aconiti Kusnezoffii, Radix Aconiti, RADIX SAPOSHINOKOVIAE from Northeast and Rhizoma Curcumae Longae is 11-13:14-16:28-32:19-21.
3. the pharmaceutical composition of external application for curing gonarthritis according to claim 1 or 2, it is characterized in that, its raw material comprises by weight: Moschus 14-16 part, Radix Aconiti Kusnezoffii 11-13 part, Radix Aconiti 14-16 part, Flos Caryophylli 9.6-10.2 part, Radix Angelicae Dahuricae 14-16 part, Olibanum 14-16 part, Myrrha 14-16 part, RADIX SAPOSHINOKOVIAE from Northeast 28-32 part, Rhizoma Curcumae Longae 19-21 part, Borneolum Syntheticum 9.5-10.5 part, Flos Carthami 14-16 part, Mentholum 14-16 part, Rhizoma Et Radix Notopterygii 14-16 part, Sanguis Draxonis 11-13 part.
4. the pharmaceutical composition of external application for curing gonarthritis according to any one of claim 1-3, is characterized in that, the weight ratio of Moschus, the Radix Angelicae Dahuricae, Olibanum, Myrrha, Flos Carthami, Mentholum and Rhizoma Et Radix Notopterygii is 1:1:1:1:1:1:1.
5. the pharmaceutical composition of external application for curing gonarthritis according to any one of claim 1-4, it is characterized in that, its raw material comprises by weight: 15 parts, Moschus, Radix Aconiti Kusnezoffii 12 parts, Radix Aconiti 15 parts, Flos Caryophylli 10 parts, the Radix Angelicae Dahuricae 15 parts, Olibanum 15 parts, Myrrha 15 parts, RADIX SAPOSHINOKOVIAE from Northeast 30 parts, 20 parts, Rhizoma Curcumae Longae, Borneolum Syntheticum 10 parts, 15 parts, Flos Carthami, Mentholum 15 parts, Rhizoma Et Radix Notopterygii 15 parts, Sanguis Draxonis 12 parts.
6. the pharmaceutical composition preparation method of an external application for curing gonarthritis as described in any one of claim 1-5, it is characterized in that, blended to Moschus, Radix Aconiti Kusnezoffii, Radix Aconiti, Flos Caryophylli, the Radix Angelicae Dahuricae, Olibanum, Myrrha, RADIX SAPOSHINOKOVIAE from Northeast, Rhizoma Curcumae Longae, Borneolum Syntheticum, Flos Carthami, Mentholum, Rhizoma Et Radix Notopterygii and Sanguis Draxonis rear pulverizing is obtained mixed material, then adds yellow wine and be stirred to the pharmaceutical composition that pasty state obtains external application for curing gonarthritis.
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Cited By (3)
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| CN106310105A (en) * | 2015-06-16 | 2017-01-11 | 王新钢 | Medicine for treating joint diseases and preparation method of medicine |
| CN107308417A (en) * | 2017-07-31 | 2017-11-03 | 北京正黄堂满族医药研究院 | A kind of full decoction method of ointment side in imperial palace |
| CN110038105A (en) * | 2019-05-23 | 2019-07-23 | 杨新民 | Knee joint Medical cold application |
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