CN104587181A - Traditional Chinese medicine composition for treating coronary heart disease - Google Patents
Traditional Chinese medicine composition for treating coronary heart disease Download PDFInfo
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- CN104587181A CN104587181A CN201510061758.0A CN201510061758A CN104587181A CN 104587181 A CN104587181 A CN 104587181A CN 201510061758 A CN201510061758 A CN 201510061758A CN 104587181 A CN104587181 A CN 104587181A
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Abstract
The invention relates to a traditional Chinese medicine composition for treating the coronary heart disease. The composition is prepared from the following components in parts by weight: 6-20 parts of ginseng, 10-25 parts of salvia miltiorrhiza, 6-12 parts of schisandra chinensis, 10-20 parts of radix ophiopogonis, 1-5 parts of asarum, 6-15 parts of ligusticum wallichii, 15-20 parts of astragalus membranaceus, 10-15 parts of cassia twig, 6-12 parts of dalbergia odorifera, 6-12 parts of longstamen onion bulb, 15-30 parts of trichosanthes kirilowii maxim, 10-15 parts of rhizoma corydalis, 10-15 parts of radix paeoniae rubra, 6-15 parts of pseudo-ginseng, 6-12 parts of honey-fried licorice root, 10-20 parts of codonopsis pilosula, 6-15 parts of leech, 6-10 parts of safflower carthamus, 6-15 parts of peach kernel and 10-18 parts of rhizoma cyperi. The traditional Chinese medicine composition is prepared from components which are influenced one another and synergetic, has a remarkable curative effect, and is worthy of great popularization.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of Chinese medicine composition for the treatment of coronary heart disease.
Background technology
Angina pectoris refers to luminal stenosis caused by coronary atherosclerosis or spasm, coronary insufficiency and cause with cardiac muscle sharply, clinical syndrome that temporary transient ischemia, anoxia are feature.Its feature is based on squeezing property pain after paroxysmal breastbone.Primary disease belongs to the category such as Chinese medicine " thoracic obstruction ", " pained ", " precordial pain with cold limbs ".
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition for the treatment of coronary heart disease.
In order to realize object of the present invention, the invention provides a kind of Chinese medicine composition for the treatment of coronary heart disease, it comprises the material of following weight portion: Radix Ginseng 6-20 part, Radix Salviae Miltiorrhizae 10-25 part, Fructus Schisandrae Chinensis 6-12 part, Radix Ophiopogonis 10-20 part, Herba Asari 1-5 part, Rhizoma Chuanxiong 6-15 part, Radix Astragali 15-20 part, Ramulus Cinnamomi 10-15 part, Lignum Dalbergiae Odoriferae 6-12 part, Bulbus Allii Macrostemonis 6-12 part, Fructus Trichosanthis 15-30 part, Rhizoma Corydalis 10-15 part, Radix Paeoniae Rubra 10-15 part, Radix Notoginseng 6-15 part, Radix Glycyrrhizae Preparata 6-12 part, Radix Codonopsis 10-20 part, Hirudo 6-15 part, Flos Carthami 6-10 part, Semen Persicae 6-15 part and Rhizoma Cyperi 10-18 part.
Preferably, the Chinese medicine composition of described treatment coronary heart disease comprises the material of following weight portion: Radix Ginseng 15 parts, Radix Salviae Miltiorrhizae 12 parts, Fructus Schisandrae Chinensis 10 parts, Radix Ophiopogonis 15 parts, Herba Asari 3 parts, Rhizoma Chuanxiong 10 parts, the Radix Astragali 18 parts, Ramulus Cinnamomi 12 parts, Lignum Dalbergiae Odoriferae 10 parts, Bulbus Allii Macrostemonis 10 parts, Fructus Trichosanthis 20 parts, Rhizoma Corydalis 12 parts, Radix Paeoniae Rubra 12 parts, Radix Notoginseng 10 parts, Radix Glycyrrhizae Preparata 10 parts, Radix Codonopsis 15 parts, Hirudo 10 parts, 8 parts, Flos Carthami, 10 parts, Semen Persicae and Rhizoma Cyperi 15 parts.
Preferably, the Chinese medicine composition of described treatment coronary heart disease also comprises the material of following weight portion: Herba Stylophori Lasiocapi 9 parts, nine pipe blood 6 parts, Herba Cyperi Iriae 12 parts, Herba Cistanches 8 parts, magnificent winged euonymus 6 parts, Cortex Albiziae 10 parts, Herba Artemisiae Anomalae 9 parts, Radix Campylotropis Macrocarpae 7 parts, Amur Adonis Herb 12 parts, Cortex Cinnamomi Burmannii 7 parts, Herba Murdanniae Nudiflorae 11 parts, Herba Wedeliae Prostratae 8 parts, Herba Salomoniae Cantoniensis 8 parts and Herba Briggsiae Chienii 6 parts.
Preferably, described Chinese medicine composition can be tablet, dispersible tablet, capsule, pill or decoction.
The present invention also provides the purposes of compositions in the Chinese medicine of preparation treatment coronary heart disease, and described compositions comprises the material of following weight portion: Radix Ginseng 6-20 part, Radix Salviae Miltiorrhizae 10-25 part, Fructus Schisandrae Chinensis 6-12 part, Radix Ophiopogonis 10-20 part, Herba Asari 1-5 part, Rhizoma Chuanxiong 6-15 part, Radix Astragali 15-20 part, Ramulus Cinnamomi 10-15 part, Lignum Dalbergiae Odoriferae 6-12 part, Bulbus Allii Macrostemonis 6-12 part, Fructus Trichosanthis 15-30 part, Rhizoma Corydalis 10-15 part, Radix Paeoniae Rubra 10-15 part, Radix Notoginseng 6-15 part, Radix Glycyrrhizae Preparata 6-12 part, Radix Codonopsis 10-20 part, Hirudo 6-15 part, Flos Carthami 6-10 part, Semen Persicae 6-15 part and Rhizoma Cyperi 10-18 part.
Preferably, described compositions comprises the material of following weight portion: Radix Ginseng 15 parts, Radix Salviae Miltiorrhizae 12 parts, Fructus Schisandrae Chinensis 10 parts, Radix Ophiopogonis 15 parts, Herba Asari 3 parts, Rhizoma Chuanxiong 10 parts, the Radix Astragali 18 parts, Ramulus Cinnamomi 12 parts, Lignum Dalbergiae Odoriferae 10 parts, Bulbus Allii Macrostemonis 10 parts, Fructus Trichosanthis 20 parts, Rhizoma Corydalis 12 parts, Radix Paeoniae Rubra 12 parts, Radix Notoginseng 10 parts, Radix Glycyrrhizae Preparata 10 parts, Radix Codonopsis 15 parts, Hirudo 10 parts, 8 parts, Flos Carthami, 10 parts, Semen Persicae and Rhizoma Cyperi 15 parts.
Preferably, described compositions also comprises the material of following weight portion: Herba Stylophori Lasiocapi 9 parts, nine pipe blood 6 parts, Herba Cyperi Iriae 12 parts, Herba Cistanches 8 parts, magnificent winged euonymus 6 parts, Cortex Albiziae 10 parts, Herba Artemisiae Anomalae 9 parts, Radix Campylotropis Macrocarpae 7 parts, Amur Adonis Herb 12 parts, Cortex Cinnamomi Burmannii 7 parts, Herba Murdanniae Nudiflorae 11 parts, Herba Wedeliae Prostratae 8 parts, Herba Salomoniae Cantoniensis 8 parts and Herba Briggsiae Chienii 6 parts.
Preferably, described Chinese medicine can be tablet, dispersible tablet, capsule, pill or decoction.
Chinese medicine composition of the present invention interacts, and synergism is evident in efficacy, highly widelys popularize.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Unless otherwise stated, the percent in the present invention is percetage by weight.
Embodiment 1 decoction of the present invention
Take Radix Ginseng 15 grams, Radix Salviae Miltiorrhizae 12 grams, Fructus Schisandrae Chinensis 10 grams, Radix Ophiopogonis 15 grams, Herba Asari 3 grams, Rhizoma Chuanxiong 10 grams, the Radix Astragali 18 grams, Ramulus Cinnamomi 12 grams, Lignum Dalbergiae Odoriferae 10 grams, Bulbus Allii Macrostemonis 10 grams, Fructus Trichosanthis 20 grams, Rhizoma Corydalis 12 grams, Radix Paeoniae Rubra 12 grams, Radix Notoginseng 10 grams, Radix Glycyrrhizae Preparata 10 grams, Radix Codonopsis 15 grams, Hirudo 10 grams, 8 grams, Flos Carthami, 10 grams, Semen Persicae and Rhizoma Cyperi 15 grams, add 7000 ml waters, heating 5 hours under the condition of backflow, filter, filtrate is made to be cooled to room temperature, adding dehydrated alcohol to alcohol content is 85 volume %, hold over night, filter, ethanol in filtrate is reclaimed completely, to obtain final product.
Embodiment 2 decoction of the present invention
Take Radix Ginseng 15 grams, Radix Salviae Miltiorrhizae 12 grams, Fructus Schisandrae Chinensis 10 grams, Radix Ophiopogonis 15 grams, Herba Asari 3 grams, Rhizoma Chuanxiong 10 grams, the Radix Astragali 18 grams, Ramulus Cinnamomi 12 grams, Lignum Dalbergiae Odoriferae 10 grams, Bulbus Allii Macrostemonis 10 grams, Fructus Trichosanthis 20 grams, Rhizoma Corydalis 12 grams, Radix Paeoniae Rubra 12 grams, Radix Notoginseng 10 grams, Radix Glycyrrhizae Preparata 10 grams, Radix Codonopsis 15 grams, Hirudo 10 grams, 8 grams, Flos Carthami, 10 grams, Semen Persicae, Rhizoma Cyperi 15 grams, Herba Stylophori Lasiocapi 9 grams, nine pipe blood 6 grams, Herba Cyperi Iriae 12 grams, Herba Cistanches 8 grams, China's winged euonymus 6 grams, Cortex Albiziae 10 grams, Herba Artemisiae Anomalae 9 grams, Radix Campylotropis Macrocarpae 7 grams, Amur Adonis Herb 12 grams, Cortex Cinnamomi Burmannii 7 grams, Herba Murdanniae Nudiflorae 11 grams, Herba Wedeliae Prostratae 8 grams, Herba Salomoniae Cantoniensis 8 grams and Herba Briggsiae Chienii 6 grams, add 7000 ml waters, heating 5 hours under the condition of backflow, filter, filtrate is made to be cooled to room temperature, adding dehydrated alcohol to alcohol content is 85 volume %, hold over night, filter, ethanol in filtrate is reclaimed completely, obtain.
Experimental example
Diagnostic criteria
Reference 2002 " new Chinese medicine guideline of clinical investigations " (Zheng Xiao cornel is edited. new Chinese medicine guideline of clinical investigations [S]. and the 1st edition Beijing: China Medical Science Press, 200269-73.) formulate.Dialectical genus heart blood silt: main symptom: chest pain or breast vexed; Secondary card: painful area is fixing not to be moved, pain is drawn inside the shoulder back of the body or arm, palpitation and uneasiness, and lip is purple dark; Picture of the tongue: purplish tongue or have ecchymosis; Pulse condition: hesitant pulse.Have one of main symptom, secondary card has more than 2 or 2 persons, in conjunction with tongue arteries and veins and diagnosable.
The Treating Patients of Angina Pectoris that 68 examples are made a definite diagnosis.Be divided into two groups, treatment group 1 and treatment group 2, in treatment group 1 36 example, male 24 example, women 12 example, age 41-65 year, 51 years old mean age; The course of disease 3 months-3 years, average 1.5 years; Wherein stable angina pectoris 16 example, unstable angina pectoris 20 example.In treatment group 2 32 example, male 20 example, women 12 example, age 40-62 year, average 52 years old; The course of disease 6 months-4 years, average 1.6 years.Wherein stable angina pectoris 16 example, unstable angina pectoris 16 example.Get rid of acute myocardial infarction, the heart disease of other types, gestation and women breast-feeding their children, hepatic and kidney function obstacle patient.Two groups of ages, sex, angina pectoris type and there was no significant differences such as the order of severity, the course of disease (P > 0.05), have comparability.
Treatment group 1 uses the decoction of preparation in embodiment 1 to treat, every day twice, at every turn oral 50 milliliters of decoctions, continuously treatment 3 months.
Treatment group 2 uses the decoction of preparation in embodiment 2 to treat, every day twice, at every turn oral 50 milliliters of decoctions, continuously treatment 3 months.
Observation index
Observe angina pectoris attacks number of times, degree, persistent period and other symptom variation before and after treatment; Detect electrocardiogram, blood fat, blood glucose, routine blood test, routine urinalysis, hepatic and renal function before and after treatment, and observe adverse effect.
Criterion of therapeutical effect
According to (Ministry of Health of the People's Republic of China. new Chinese medicine guideline of clinical investigations the 1st volume of [S] 1993:41-45.) formulate.Effective: equal tired degree does not cause uncomfortable in chest, angina pectoris or angina pectoris attacks number of times to be less than more than 80%.Effective: uncomfortable in chest, angina pectoris attacks number of times reduces 50%-80%.Invalid: uncomfortable in chest, angina pectoris attacks number of times reduces less than 50%.
Statistical method
Utilize SPSS 13.0 software to process and analyze to experimental data, measurement data is with mean ± standard deviation
represent, adopt t inspection, enumeration data adopts χ
2inspection, P < 0.05 represents that difference has statistical significance.
Result
Through treatment, for treatment group 1, effective 11 examples, effective 20 examples, invalid 5 examples, total effective rate is 86.1%, and for treatment group 2, effective 19 examples, effective 11 examples, invalid 2 examples, total effective rate is 93.8%.Two groups of total effective rate comparing differences have statistical significance (P < 0.05).Two groups treatments period hematuria is conventional, hepatic and renal function detection is without exception, does not find obvious untoward reaction.
Claims (8)
1. treat the Chinese medicine composition of coronary heart disease for one kind, it is characterized in that, it comprises the material of following weight portion: Radix Ginseng 6-20 part, Radix Salviae Miltiorrhizae 10-25 part, Fructus Schisandrae Chinensis 6-12 part, Radix Ophiopogonis 10-20 part, Herba Asari 1-5 part, Rhizoma Chuanxiong 6-15 part, Radix Astragali 15-20 part, Ramulus Cinnamomi 10-15 part, Lignum Dalbergiae Odoriferae 6-12 part, Bulbus Allii Macrostemonis 6-12 part, Fructus Trichosanthis 15-30 part, Rhizoma Corydalis 10-15 part, Radix Paeoniae Rubra 10-15 part, Radix Notoginseng 6-15 part, Radix Glycyrrhizae Preparata 6-12 part, Radix Codonopsis 10-20 part, Hirudo 6-15 part, Flos Carthami 6-10 part, Semen Persicae 6-15 part and Rhizoma Cyperi 10-18 part.
2. the Chinese medicine composition for the treatment of coronary heart disease according to claim 1, it is characterized in that, it comprises the material of following weight portion: Radix Ginseng 15 parts, Radix Salviae Miltiorrhizae 12 parts, Fructus Schisandrae Chinensis 10 parts, Radix Ophiopogonis 15 parts, Herba Asari 3 parts, Rhizoma Chuanxiong 10 parts, the Radix Astragali 18 parts, Ramulus Cinnamomi 12 parts, Lignum Dalbergiae Odoriferae 10 parts, Bulbus Allii Macrostemonis 10 parts, Fructus Trichosanthis 20 parts, Rhizoma Corydalis 12 parts, Radix Paeoniae Rubra 12 parts, Radix Notoginseng 10 parts, Radix Glycyrrhizae Preparata 10 parts, Radix Codonopsis 15 parts, Hirudo 10 parts, 8 parts, Flos Carthami, 10 parts, Semen Persicae and Rhizoma Cyperi 15 parts.
3. the Chinese medicine composition for the treatment of coronary heart disease according to claim 1 and 2, it is characterized in that, it also comprises the material of following weight portion: Herba Stylophori Lasiocapi 9 parts, nine pipe blood 6 parts, Herba Cyperi Iriae 12 parts, Herba Cistanches 8 parts, magnificent winged euonymus 6 parts, Cortex Albiziae 10 parts, Herba Artemisiae Anomalae 9 parts, Radix Campylotropis Macrocarpae 7 parts, Amur Adonis Herb 12 parts, Cortex Cinnamomi Burmannii 7 parts, Herba Murdanniae Nudiflorae 11 parts, Herba Wedeliae Prostratae 8 parts, Herba Salomoniae Cantoniensis 8 parts and Herba Briggsiae Chienii 6 parts.
4. the Chinese medicine composition for the treatment of coronary heart disease according to claim 3, is characterized in that, described Chinese medicine composition can be tablet, dispersible tablet, capsule, pill or decoction.
5. the purposes of compositions in the Chinese medicine of preparation treatment coronary heart disease, it is characterized in that, described compositions comprises the material of following weight portion: Radix Ginseng 6-20 part, Radix Salviae Miltiorrhizae 10-25 part, Fructus Schisandrae Chinensis 6-12 part, Radix Ophiopogonis 10-20 part, Herba Asari 1-5 part, Rhizoma Chuanxiong 6-15 part, Radix Astragali 15-20 part, Ramulus Cinnamomi 10-15 part, Lignum Dalbergiae Odoriferae 6-12 part, Bulbus Allii Macrostemonis 6-12 part, Fructus Trichosanthis 15-30 part, Rhizoma Corydalis 10-15 part, Radix Paeoniae Rubra 10-15 part, Radix Notoginseng 6-15 part, Radix Glycyrrhizae Preparata 6-12 part, Radix Codonopsis 10-20 part, Hirudo 6-15 part, Flos Carthami 6-10 part, Semen Persicae 6-15 part and Rhizoma Cyperi 10-18 part.
6. purposes according to claim 5, it is characterized in that, described compositions comprises the material of following weight portion: Radix Ginseng 15 parts, Radix Salviae Miltiorrhizae 12 parts, Fructus Schisandrae Chinensis 10 parts, Radix Ophiopogonis 15 parts, Herba Asari 3 parts, Rhizoma Chuanxiong 10 parts, the Radix Astragali 18 parts, Ramulus Cinnamomi 12 parts, Lignum Dalbergiae Odoriferae 10 parts, Bulbus Allii Macrostemonis 10 parts, Fructus Trichosanthis 20 parts, Rhizoma Corydalis 12 parts, Radix Paeoniae Rubra 12 parts, Radix Notoginseng 10 parts, Radix Glycyrrhizae Preparata 10 parts, Radix Codonopsis 15 parts, Hirudo 10 parts, 8 parts, Flos Carthami, 10 parts, Semen Persicae and Rhizoma Cyperi 15 parts.
7. the purposes according to claim 5 or 6, it is characterized in that, described compositions also comprises the material of following weight portion: Herba Stylophori Lasiocapi 9 parts, nine pipe blood 6 parts, Herba Cyperi Iriae 12 parts, Herba Cistanches 8 parts, magnificent winged euonymus 6 parts, Cortex Albiziae 10 parts, Herba Artemisiae Anomalae 9 parts, Radix Campylotropis Macrocarpae 7 parts, Amur Adonis Herb 12 parts, Cortex Cinnamomi Burmannii 7 parts, Herba Murdanniae Nudiflorae 11 parts, Herba Wedeliae Prostratae 8 parts, Herba Salomoniae Cantoniensis 8 parts and Herba Briggsiae Chienii 6 parts.
8. purposes according to claim 7, is characterized in that, described Chinese medicine can be tablet, dispersible tablet, capsule, pill or decoction.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105288243A (en) * | 2015-11-29 | 2016-02-03 | 张量才 | Traditional Chinese medicine for curing cerebral infarction, cerebral palsy, cerebral atrophy, thoracic obstruction, coronary disease and stenocardia |
| CN105641399A (en) * | 2015-12-23 | 2016-06-08 | 夏京奎 | Traditional Chinese medicine alternative to bypass or stent |
| CN108339094A (en) * | 2018-05-18 | 2018-07-31 | 重庆跃龙生物制药有限公司 | Chinese medicine composition and preparation method thereof for treating coronary heart disease |
| CN109172645A (en) * | 2018-11-21 | 2019-01-11 | 思南县人民医院 | A kind of Chinese medicine composition and preparation method thereof for treating gastric ulcer |
| CN110538290A (en) * | 2018-05-29 | 2019-12-06 | 李天生 | First-aid medicine liquid and its preparing method |
| CN111603534A (en) * | 2020-07-08 | 2020-09-01 | 安阳市中医院 | Chinese medicinal granule for treating coronary heart disease and preparation method thereof |
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| CN101612349A (en) * | 2009-07-17 | 2009-12-30 | 翟修祥 | The medicine of treatment coronary heart disease |
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2015
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Patent Citations (1)
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| CN101612349A (en) * | 2009-07-17 | 2009-12-30 | 翟修祥 | The medicine of treatment coronary heart disease |
Non-Patent Citations (1)
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| 苏瑞君，等: "益气活血法治疗冠心病71例", 《吉林中医药》 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105288243A (en) * | 2015-11-29 | 2016-02-03 | 张量才 | Traditional Chinese medicine for curing cerebral infarction, cerebral palsy, cerebral atrophy, thoracic obstruction, coronary disease and stenocardia |
| CN105641399A (en) * | 2015-12-23 | 2016-06-08 | 夏京奎 | Traditional Chinese medicine alternative to bypass or stent |
| CN108339094A (en) * | 2018-05-18 | 2018-07-31 | 重庆跃龙生物制药有限公司 | Chinese medicine composition and preparation method thereof for treating coronary heart disease |
| CN110538290A (en) * | 2018-05-29 | 2019-12-06 | 李天生 | First-aid medicine liquid and its preparing method |
| CN109172645A (en) * | 2018-11-21 | 2019-01-11 | 思南县人民医院 | A kind of Chinese medicine composition and preparation method thereof for treating gastric ulcer |
| CN111603534A (en) * | 2020-07-08 | 2020-09-01 | 安阳市中医院 | Chinese medicinal granule for treating coronary heart disease and preparation method thereof |
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Application publication date: 20150506 |