CN104569379B - Smart mobile phone fast immune chromatographic test paper bar supporting detection device - Google Patents
Smart mobile phone fast immune chromatographic test paper bar supporting detection device Download PDFInfo
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- CN104569379B CN104569379B CN201510003280.6A CN201510003280A CN104569379B CN 104569379 B CN104569379 B CN 104569379B CN 201510003280 A CN201510003280 A CN 201510003280A CN 104569379 B CN104569379 B CN 104569379B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
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Abstract
The invention discloses a kind of smart mobile phone fast immune chromatographic test paper bar supporting detection device, including collimating lens, optical fibers and test strips inlet unit, there is on test strips inlet unit the socket receiving immunity layer test strips, there is in test strips inlet unit the light source for irradiating test strips, fibre-optic one end is connected with test strips inlet unit and draws test strips inlet unit with the reflection light by the image of reflection test strips, collimating lens makes fibre-optic emergent light be radiated at collimatedly on the camera lens of smart mobile phone, so that smart mobile phone obtains the image of test strips and can carry out the image of test strips processing and output detections result by the software that processes installed on it.The present invention can realize the core carrier processed with smart mobile phone as image and data, completes the detection to test strips.The present invention has good popularization, and its portability is the best, may be used for the ELISA test strip under any environment.
Description
Technical field
The present invention relates to chromatograph test strip detection technique, particularly relate to a kind of smart mobile phone fast immune chromatographic test paper bar
Supporting detection device.
Background technology
Since the nineties in 20th century, immunochromatography technique is examined due to its part quick, easy, economic, single
The features such as survey are developed rapidly, now have been widely used for medical science detection, food quality monitoring, illicit drugs inspection and
Environmental monitoring.At present, immunochromatography technique develops towards high sensitivity, quantitative and multivariate detection direction, and
It is likely to become the early stage of pathogen, malignant tumor and cardiovascular disease etc. effective and sensitive sieving and diagnosis skill
Art.
Existing immuno-chromatographic test paper strip detecting system includes test strips, matched reagent and detection equipment.Sample to be tested
After reacting with immuno-chromatographic test paper strip and matched reagent, the bio information in test strips passes through bio information identifier,
Through the image acquisition of software, analyze and add powerful, finally obtaining a result.Due to immunochromatography technique operation letter
Single, quickly, specificity is good, and result understands, it is easy to judges and preserves, and without or only need simple instrument and material
Material, so being usually used in bedside detection and the large area examination of non-hospital.In order to coordinate these base application, chromatography inspection
The exploitation of examining system is inevitable to be developed towards direction miniature, portable.And complete detecting system can help operation
Personnel obtain testing result more accurately, reduce impact and the erroneous judgement of environment.
Current biological immune chromatographic detector is the most all with computer for processing the core carrier of data, first uses
LED light source irradiates test strips, then with industrial camera (CCD camera lens) as image capture device, will obtain
Test strips image pass to computer, be detected and analyzed with special image processing software on computers, final
To testing result.This detector is highly sensitive, but cost of manufacture is higher, and volume is relatively big, carries inconvenience.And
And some test strips is not easy to transport and stores, transportation is vulnerable to interference, if being sent to desk-top setting
Standby biological immune chromatographic detector there necessarily affects testing result.
Therefore, those skilled in the art is devoted to develop a kind of portable smart mobile phone fast immune chromatographic test paper bar
Supporting detection device.
Summary of the invention
Because the drawbacks described above of prior art, the technical problem to be solved is to provide a kind of smart mobile phone
Fast immune chromatographic test paper bar supporting detection device, by utilizing smart mobile phone, as the core of image procossing
Carrier, it is achieved to immuno-chromatographic test paper strip easily and fast, detect anywhere or anytime.
For achieving the above object, the invention provides a kind of smart mobile phone fast immune chromatographic test paper bar supporting detection dress
Put, it is characterised in that include collimating lens, optical fibers and test strips inlet unit, described test strips socket list
There is in unit the socket receiving immunity layer test strips, have for irradiating described reagent paper in described test strips inlet unit
The light source of bar, described fibre-optic one end is connected with described test strips inlet unit to reflect described test strips
The reflection light of image draws described test strips inlet unit, and described collimating lens makes described fibre-optic emergent light accurate
Directly it is radiated on the camera lens of smart mobile phone.
Further, the image described smart mobile phone being provided with the described test strips for receiving described camera lens enters
Row processes and the process software of output detections result.
Further, the described fibre-optic other end is at a focal point of described collimating lens.
Further, another focus of described collimating lens is in the focal plane of the described camera lens of described smart mobile phone
On.
Further, shell, described collimating lens, described optical fibers and described test strips inlet unit are also included
Fix in the housing.
Further, described shell is further fixed on the housing main body for receiving described smart mobile phone, when described intelligence
Energy mobile phone is when described housing main body inserts and puts in place, and another focus of described collimating lens is at described smart mobile phone
On the focal plane of described camera lens.
Further, the described housing main body in described shell can be changed with the smart mobile phone of adaptive different model.
Further, described test strips is arranged to the institute with described smart mobile phone in described test strips inlet unit
State the described focal plane of camera lens in angle of 45 degrees.
Further, the described socket of described test strips inlet unit is arranged to when described test strips being inserted from described
Mouth pushes described test strips inlet unit when putting in place, and described test strips is arranged in described test strips inlet unit
With the described focal plane of the described camera lens of described smart mobile phone in angle of 45 degrees.
Further, described light source is LED.
Further, also including power supply in described test strips inlet unit, described power supply is for supplying to described LED
Electricity.
Further, described power supply is lithium battery.
In the better embodiment of the present invention, it is provided that a kind of supporting inspection of smart mobile phone fast immune chromatographic test paper bar
Surveying device, it includes collimating lens, optical fibers and test strips inlet unit.Wherein collimating lens, optical fibers
Being fixed in a shell closed according to defined location relation with test strips inlet unit, shell is also gone up the most fixing
There is one for the housing main body receiving smart mobile phone.Test strips inlet unit is provided with the socket receiving test strips,
LED and power supply it is provided with in test strips inlet unit.When smart mobile phone housing main body insert put in place, test strips from
Socket pushes test strips inlet unit when putting in place, i.e. meets image imaging on the camera lens of smart mobile phone of test strips
Requirement, the image of test strips can be carried out processing and output detections knot by the process software thus installed on smart mobile phone
Really.
As can be seen here, the smart mobile phone fast immune chromatographic test paper bar supporting detection device of the present invention is by arranging
Shell, by each assembly fix in position needed for detection, can quickly enable and operate without being directed at focusing etc.,
Use very convenient.Further, by housing main body removable on shell, various model can advantageously be used
Smart mobile phone.Therefore, the smart mobile phone fast immune chromatographic test paper bar supporting detection device of the present invention can be real
The core carrier now processed as image and data with smart mobile phone, mixes it by the photographic head of mobile phone
His optical lens, completes the work of image acquisition link, with by the image of test strips to the place installed on mobile phone
Reason software, thus complete the detection to test strips.Fast development and cell phone software due to present smart mobile phone
Extensive application, the present invention has good popularization, and its portability is the best, may be used for appointing
ELISA test strip under what environment.
Below with reference to accompanying drawing, the technique effect of design, concrete structure and the generation of the present invention is described further,
To be fully understood from the purpose of the present invention, feature and effect.
Accompanying drawing explanation
Fig. 1 is in a preferred embodiment, the supporting inspection of smart mobile phone fast immune chromatographic test paper bar of the present invention
Survey the axonometric chart of device.
Fig. 2 be the smart mobile phone fast immune chromatographic test paper bar supporting detection device of the present invention shown in Fig. 1 on regard
Schematic diagram, smart mobile phone therein is placed in housing main body.
Detailed description of the invention
As illustrated in fig. 1 and 2, in a preferred embodiment, the smart mobile phone fast immune chromatographic examination of the present invention
Paper slip supporting detection device includes collimating lens 130, optical fibers 120 and test strips inlet unit 110, wherein
Collimating lens 130, optical fibers 120 and test strips inlet unit 110 are fixed on one according to defined location relation
In the shell 100 of individual closing, the closing of shell 100 here refers to that it can intercept the impact of extraneous light, shell
100 also on be further fixed on one for the housing main body 140 receiving smart mobile phone 300.
One sidewall of test strips inlet unit 110 is provided with and leads to its internal socket, for for test strips 200
Insert from which in test strips inlet unit 110, insert the test strips 200 put in place in test strips inlet unit 110
It is arranged to the focal plane of camera lens with smart mobile phone 300 in angle of 45 degrees；Owing to the photoconduction in the present embodiment is fine
Dimension 120 is straight, i.e. the light path from test strips inlet unit 110 to the camera lens of smart mobile phone 300 is and photoconduction
The straight line that fiber 120 overlaps, test strips 200 also becomes 65 degree of angles, optical fibers 120 with optical fibers 120
Then the focal plane with the camera lens of smart mobile phone 300 becomes 70 degree of angles.Owing to test strips 200 is partially into examination
In paper slip inlet unit 110, it is partly exposed to outside socket, and socket the most here also makes test strips 200
Keep its state relative to the inclination of the focal plane of the camera lens of smart mobile phone 300.
Test strips inlet unit 110 is internal has light source, for being radiated at the reagent paper in test strips inlet unit 110
Bar 200, in the present embodiment, the light source within test strips inlet unit 110 is LED.Test strips inlet unit 110
Internal also have the power supply providing electric power for light source, is lithium battery in the present embodiment.Selection LED light source is because
Its power consumption is less, only need to configure two pieces of lithium batteries as power supply, can ensure the long-time use of this light source.
Optical fibers 120 has two ends, and light enters from one end thereof (first end), from its another
End (the second end) is penetrated.In the present embodiment, the first end of optical fibers 120 is connected to test strips socket
Unit 110, is specifically connected to the optical emission exit of test strips inlet unit 110.By test strips inlet unit 110
The test strips 200 that interior light source irradiates launches reflection light, and this reflection light reflects the image of test strips 200, its
Drawn by optical fibers 120 from the optical emission exit of test strips inlet unit 110.
The light of the second end leaving optical fibers 120 needs to collimate through collimating lens 130, to retrain the biography of light
Broadcast, reduce light scattering in communication process.In the present embodiment, collimating lens 130 has two focuses, respectively
Being the first focus and the second focus, the second end of optical fibers 120 is arranged in the first focus of collimating lens 130
Place, on the focal plane of the camera lens that the second focus of collimating lens 130 is arranged in smart mobile phone 300.Thus, leave
The light of collimating lens 130 can be gathered imaging by smart mobile phone 300, i.e. smart mobile phone 300 gets test strips
The image of 200.Owing to the pixel of camera lens (photographic head) and the shooting effect of current smart mobile phone are fully able to full
The foot collection to test strips image, it can be substantially reduced the picture noise in image acquisition process, it is ensured that gathers figure
The quality of picture.
Owing to the Main Function of smart mobile phone 300 is not used to the smart mobile phone fast immune chromatographic examination of the present invention
Paper slip supporting detection device, the most preferably it should not be such as collimating lens 130, optical fibers 120 and test strips
Inlet unit 110 is fixed on shell 100 like that and really positions and put, and it should be dismountable, and energy side
Just insert shell really to position to put and operate exempting alignment, focusing etc..In the present embodiment, on shell 100 outside
Shell main body 140 is precisely in order to realize above-mentioned requirement.Housing main body 140 is fixed on shell 100, preferably
It is a groove-like structure, and smart mobile phone 300 inserts from the opening of this groove with the direction that determines after putting in place, can meet
Second focus of above-mentioned imaging requirements, i.e. collimating lens 130 falls on the focal plane of the camera lens of smart mobile phone 300.
It is thus preferable to, should the inserted mode of indicating intelligent mobile phone 300 on housing main body 140.
Owing to smart mobile phone 300 can be disposable type, in order to mate the smart mobile phone 300 of different model, should
This applies different housing main bodies 140 accordingly.Therefore, housing main body 140 is detachable, specifically
For the model of the smart mobile phone 300 according to user, select adaptive housing main body 140, and by this housing main body
140 are loaded on shell 100 suitable position.It is thus preferable to, shell 100 should have for fixing
The position of different housing main bodies 140.
The image being provided with the test strips 200 for receiving its camera lens on smart mobile phone 300 processes and exports
The process software of testing result, this software with the analysis software of installation in the computer of the table tester of prior art is
Being similar to, it can store and be loaded into acquired image, be entered by the image of image with the master sample in data base
Row contrast, and output detections result.Here data base can be stored in advance on smart mobile phone 300；Can also
It is at server end, is obtained by wireless network by smart mobile phone 300.
Using the smart mobile phone fast immune chromatographic test paper bar supporting detection device of the present invention when, it is first turned on
The above-mentioned process software of smart mobile phone 300, inserts housing main body 140 by smart mobile phone 300 and puts in place, by test strips
200 sockets inserting test strips inlet unit 110 put in place, open the LED in test strips inlet unit 110, intelligence
The software that processes of energy mobile phone 300 obtains the image of test strips 200 automatically, output detections result after process.
The testing result of test strips 200 can be passed through real-time interconnection by smart mobile phone 300, immediately uploaded to cure
Raw computer, therefore, the user of the smart mobile phone fast immune chromatographic test paper bar supporting detection device of the present invention can
With at oneself or complete immuno-chromatographic test paper strip detection in community, and testing result is issued doctor, thus facilitate
Expert consultation.
The preferred embodiment of the present invention described in detail above.Should be appreciated that those of ordinary skill in the art
Just many modifications and variations can be made according to the design of the present invention without creative work.Therefore, all technology neck
The technical staff in territory is the most on the basis of existing technology by logical analysis, reasoning or limited
Test available technical scheme, all should be in the protection domain being defined in the patent claims.
Claims (3)
1. a smart mobile phone fast immune chromatographic test paper bar supporting detection device, it is characterised in that include that collimation is thoroughly
Mirror, optical fibers and test strips inlet unit, described test strips inlet unit has receiving immunity layer examination
The socket of paper slip, has the light source for irradiating described test strips in described test strips inlet unit, described
Fibre-optic one end is connected with described test strips inlet unit with the image by reflecting described test strips
Reflection light draws described test strips inlet unit, and described collimating lens makes described fibre-optic emergent light accurate
Directly it is radiated on the camera lens of smart mobile phone；
The described fibre-optic other end is at a focal point of described collimating lens；
Described collimating lens, described optical fibers and described test strips inlet unit are fixed on the shell of closing
In；Described shell is further fixed on the housing main body for receiving described smart mobile phone, when described intelligence hands
Machine is when described housing main body inserts and puts in place, and another focus of described collimating lens is at described smart mobile phone
Described camera lens focal plane on；Described housing main body in described shell is dismountable, can change
Smart mobile phone with adaptive different model；
Described socket is arranged on a sidewall of described test strips inlet unit, and described test strips is partly
It is exposed to outside socket；Described socket is arranged to when from described socket, described test strips is pushed described examination
When paper slip inlet unit puts in place, described test strips is arranged to described in described test strips inlet unit
The described focal plane of the described camera lens of smart mobile phone in angle of 45 degrees, and described test strips also with described light
Leading fiber and become 65 degree of angles, described optical fibers becomes 70 degree of angles with described focal plane.
2. smart mobile phone fast immune chromatographic test paper bar supporting detection device as claimed in claim 1, wherein said
Light source is LED.
3. smart mobile phone fast immune chromatographic test paper bar supporting detection device as claimed in claim 2, wherein said
Also including power supply in test strips inlet unit, described power supply is for powering to described LED.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510003280.6A CN104569379B (en) | 2015-01-04 | 2015-01-04 | Smart mobile phone fast immune chromatographic test paper bar supporting detection device |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510003280.6A CN104569379B (en) | 2015-01-04 | 2015-01-04 | Smart mobile phone fast immune chromatographic test paper bar supporting detection device |
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| CN104569379A CN104569379A (en) | 2015-04-29 |
| CN104569379B true CN104569379B (en) | 2016-08-24 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| TWI729002B (en) * | 2015-09-16 | 2021-06-01 | 安盛生科股份有限公司 | Method and apparatus for improving usability and accuracy for physiological measurement on mobile device |
| CN105334210A (en) * | 2015-09-18 | 2016-02-17 | 深圳市嘉世通科技有限公司 | Intelligent watch and intelligent watch-based harmful substance detection method |
| CN107884571A (en) * | 2016-09-30 | 2018-04-06 | 张磊 | Portable fluorescence immunity analysis instrument and Portable fluorescence analysis method |
| CN108226511A (en) * | 2016-12-14 | 2018-06-29 | 北京金华科生物技术有限公司 | A kind of novel saliva CRP Test papers and preparation method thereof |
| CN107121542B (en) * | 2017-04-28 | 2018-08-31 | 厦门大学 | A kind of immunity-chromatography test strip quantitative detection system and method based on mobile phone |
| CN107255712B (en) * | 2017-05-03 | 2019-08-06 | 上海交通大学 | A kind of immunochromatography chip quantified system analysis based on smart phone |
| WO2018232469A1 (en) * | 2017-06-24 | 2018-12-27 | Australian Sensing And Identification Systems Pty. Ltd | A method, device and system for facilitating image capture of test strips/materials/components |
| CN107655889A (en) * | 2017-09-22 | 2018-02-02 | 暨南大学 | Colorimetric chromatograph test strip based on smart mobile phone reads detection means and application |
| CN109358190A (en) * | 2018-11-16 | 2019-02-19 | 许金芹 | A kind of division of endocrinology's intelligence blood urine checking device |
| CN111830252B (en) * | 2020-06-30 | 2023-02-28 | 广州佰芮慷生物科技有限公司 | Enzyme-linked immunosorbent assay sensor based on intelligent mobile terminal and use method |
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| CN101285762B (en) * | 2007-04-11 | 2011-08-03 | 中国科学院电子学研究所 | Multi-parameter immunity-chromatography test strip quantitative determination instrument |
| US8889424B2 (en) * | 2011-09-13 | 2014-11-18 | Joel R. L. Ehrenkranz | Device and method for performing a diagnostic test |
| US10132802B2 (en) * | 2012-04-17 | 2018-11-20 | i-calQ, LLC | Device for performing a diagnostic test and methods for use thereof |
| CN203732451U (en) * | 2014-01-24 | 2014-07-23 | 深圳市宝凯仑科技有限公司 | Detection device suitable for scan detection of mobile phone camera |
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