CN104560692B - Biological specimen collection and pretreatment unit - Google Patents
Biological specimen collection and pretreatment unit Download PDFInfo
- Publication number
- CN104560692B CN104560692B CN201510025202.6A CN201510025202A CN104560692B CN 104560692 B CN104560692 B CN 104560692B CN 201510025202 A CN201510025202 A CN 201510025202A CN 104560692 B CN104560692 B CN 104560692B
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- CN
- China
- Prior art keywords
- collection tube
- lid
- sample
- push rod
- groove
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M45/00—Means for pre-treatment of biological substances
- C12M45/02—Means for pre-treatment of biological substances by mechanical forces; Stirring; Trituration; Comminuting
Abstract
The present invention relates to a kind of micro-biological samples collection and pretreatment unit.It includes collection tube and sample retaining devices.It is characterized in that: the bottom of collection tube is provided with the groove being prone to puncture, groove it is provided with in the middle of lid, bottom portion of groove is arranged over sponge block and cover plate, passage is had on cover plate, lid central authorities are provided with hollow form push rod, this push rod gos deep into body through the bottom of cover plate, sponge block and lid intermediate groove from top to bottom, and the push rod going deep into body portion is formed around stirring sheet.Collection tube seals with lid.Sample retaining devices is provided with collection tube room and sample pool, and the bottom of collection tube room is provided with ailhead shape protrusion.The present invention is convenient to collection and the pretreatment of biological specimen, the infection that operator are caused by the aerosol etc. that sponge block can avoid sample stirring to occur, ensure that the health of operator, enable to send to the sample random process of laboratory, improve operating efficiency and precision of analysis, be more suitable for the needs of Clinical microorganism laboratory.
Description
Technical field
The present invention relates to a kind of biological specimen being acquired and the device of pretreatment, specifically a kind of biological specimen collection and pretreatment unit.
Background technology
In hospital clinical and medical research are tested, generally require the feces to patient, urine, sputum, swab equal samples be acquired and carry out necessity pretreatment (as the digestion of sputum sample, fecal sample increase bacterium, the homogenizing of swab sample).Inventor applied for a kind of biological specimen collection pipe being exclusively used in automation bacteria separation and Culture in 2008.This patent has played certain effect when for collection and the separation and Culture of sample, and it has evaded bio-safety risk during sampling, is again a vitals of separation and Culture device simultaneously, serves the effect of key for smoothly completing automatization's separation and Culture.But this design also exists again bigger drawback.First, being stirred sputum sample with little magnetic piece, owing to stirring dynamics is inadequate, Blending Efficiency of Blending is the best, makes part sputum sample stir not open；It two easily produces aerosol when being to be stirred sputum sample, and due to the original design safeguard procedures not responded to, operator are susceptible to the pollution of sample, and healthy to operator constitutes a serious threat.In order to solve the problems referred to above, inventor designs the art of this patent, to be properly completed the digestion process to sputum sample, and the problem having evaded Aerosol Pollution in sputum digestion process.
Summary of the invention
The technical problem to be solved is the defect existed for existing biological specimen collection pipe, a kind of novel biological specimen collection and pretreatment unit are provided, can use with automation bacteria separation and Culture matched with devices, thus complete automatization's separation and Culture of biological specimen.
The technical scheme is that and be achieved in that: it includes collection tube (1), collection tube (1) is provided with lid (2), it is provided with groove (12) in the middle of lid (2), it is characterized in that: collection tube (1) bottom is connected with sample retaining devices (3), lid (2) bottom is arranged over cover plate (11) and adsorption layer (5), and adsorption layer (5) is used for filtering aerosol produced by stirring sample.Having passage (10) on cover plate (11), lid (2) central authorities are provided with hollow form push rod (4), and push rod hollow design, to be convenient to from upper end filling reagent to body；Hollow form push rod (4) is from top to bottom through cover plate (11), adsorption layer (5) and the bottom of lid groove (12), and stretch in the body of collection tube (1) in lid bottom groove (12) linking, the hollow form push rod (4) going deep into body portion is formed around stirring sheet (6), along with the rotation of push rod, stirring sheet is used for stirring sample；Collection tube (1) seals with lid (2), sample retaining devices (3) is provided with collection tube room (7) and sample pool (8), the bottom of collection tube room (7) is provided with ailhead shape protrusion (9), and collection tube room (7) and sample pool (8) pass through channel connection.Described adsorption layer (5) is sponge block or other filtering material.Described collection tube and sample retaining devices assist to use.Sample retaining devices is made up of collection tube holding chamber and sample pool two parts.The bottom of collection tube holding chamber is provided with ailhead shape protrusion, and holding chamber is interconnected by passage with sample pool.After collection tube puts into collection tube holding chamber, first driving push rod to rotate by external force, be stirred sample, after having stirred, collection tube top is pressed by design external force, and ailhead shape protrusion punctures bottom collection tube, makes liquid sample flow out, enters sample pool by passage.Complete streak inoculation and the separation and Culture process of sample the most again from culture apparatus by automatic partition.
The invention have the characteristics that:
1) biological specimen can directly collect in corresponding collection tube, and safe transport is to Microbiological Lab.Operator are without opening specimen collection tube, it is not necessary to sample can be digested, increase the pretreatment such as bacterium by contact sample, reduces the infected danger of operator.
2) by upper end filling enrichment liquid, Digestive system or the transmission substrate etc. of hollow push rod, facilitate safely.
3) for respiratory tract sample, there will be aerosol digesting it, in whipping process, the sponge block of lid general headquarters design can be avoided polluting operator.
4) sample after pretreatment completes enters sample pool by the way of unique, middle without any sample branching program, and whole process is smooth and quick.
5) saved numerous and diverse manual program, made separation and Culture more at random, more operated quickly and conveniently.
Accompanying drawing explanation
Fig. 1 is present configuration schematic diagram
Fig. 2 is the sectional view of lid of the present invention
Fig. 3 is the top view of Fig. 2
Detailed description of the invention
As shown in Figure 1 and Figure 2, the present invention includes collection tube (1), collection tube (1) is provided with lid (2), it is provided with groove (12) in the middle of lid (2), it is characterized in that: collection tube (1) bottom is connected with sample retaining devices (3), lid (2) bottom is arranged over cover plate (11) and sponge block (5), and sponge block (5) is used for filtering aerosol produced by stirring sample.As it is shown on figure 3, have passage (10) on cover plate (11), lid (2) central authorities are provided with hollow form push rod (4), and push rod hollow design, to be convenient to from upper end filling reagent to body；Hollow form push rod (4) is from top to bottom through cover plate (11), sponge block (5) and the bottom of lid groove (12), and stretch in the body of collection tube (1) in lid bottom groove (12) linking, push rod can be separated by this linking under external force with lid, releases the lid sealing to body.The hollow form push rod (4) going deep into body portion is formed around stirring sheet (6), and push rod 4 can depart from lid under external force drives and rotate, with stirring sheet 6 by sample stirring and evenly mixing when it rotates.Collection tube (1) seals with lid (2), sample retaining devices (3) is provided with collection tube room (7) and sample pool (8), the bottom of collection tube room (7) is provided with ailhead shape protrusion (9), and collection tube room (7) and sample pool (8) pass through channel connection.Described collection tube and sample retaining devices assist to use.Sample retaining devices is made up of collection tube holding chamber and sample pool two parts.The bottom of collection tube holding chamber is provided with ailhead shape protrusion, and holding chamber is interconnected by passage with sample pool.After collection tube puts into collection tube holding chamber, first driving push rod to rotate by external force, be stirred sample, after having stirred, collection tube top is pressed by design external force, and ailhead shape protrusion punctures bottom collection tube, makes liquid sample flow out, enters sample pool by passage.Complete streak inoculation and the separation and Culture process of sample the most again from culture apparatus by automatic partition.
During use, lid of directly outwarding winding, collect sample, use lid sealed tube body.By, in the upper end filling reagent of hollow form push rod (4) to collection tube 1, collection tube being put into collection tube room.External driver device rotates push rod, is stirred sample.After having stirred, collection tube top is pressed by external force, makes to be punctured by ailhead shape protrusion bottom collection tube, and sample enters sample pool by ad hoc passage；By the viscous sampling of separation and Culture device originally streak inoculation and separation and Culture action will be completed below.
Claims (2)
1. biological specimen collection and a pretreatment unit, it includes collection tube (1), on collection tube (1)
Be provided with lid (2), be provided with groove (12) in the middle of lid (2), it is characterized in that: collection tube (1) bottom with
Sample retaining devices (3) connects, and lid (2) bottom is arranged over cover plate (11) and adsorption layer (5),
Having passage (10) on cover plate (11), lid (2) central authorities are provided with hollow form push rod (4), hollow form
Push rod (4) passes cover plate (11), adsorption layer (5) and the bottom of lid groove (12) from top to bottom, and
Stretch in the body of collection tube (1) in lid bottom groove (12) linking, go deep into the hollow of body portion
Shape push rod (4) is formed around stirring sheet (6), and collection tube (1) seals with lid (2), and sample retains dress
Putting (3) and be provided with collection tube room (7) and sample pool (8), the bottom of collection tube room (7) is provided with ailhead shape
Protrusion (9), collection tube room (7) and sample pool (8) pass through channel connection.
A kind of biological specimen collection the most according to claim 1 and pretreatment unit, is characterized in that: institute
The adsorption layer (5) stated is sponge block.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510025202.6A CN104560692B (en) | 2015-01-19 | 2015-01-19 | Biological specimen collection and pretreatment unit |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510025202.6A CN104560692B (en) | 2015-01-19 | 2015-01-19 | Biological specimen collection and pretreatment unit |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104560692A CN104560692A (en) | 2015-04-29 |
| CN104560692B true CN104560692B (en) | 2017-01-04 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510025202.6A Active CN104560692B (en) | 2015-01-19 | 2015-01-19 | Biological specimen collection and pretreatment unit |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104560692B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111081514A (en) * | 2020-01-06 | 2020-04-28 | 南通大学 | A fixed pipe of transmission electron microscope biological sample for long-range sending |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2799572Y (en) * | 2005-06-16 | 2006-07-26 | 姜世民 | Automatic separation and culturing device for biological sample |
| CN201099684Y (en) * | 2007-08-31 | 2008-08-13 | 姜世民 | Biological specimen four sides isolated culture device |
| CN201560183U (en) * | 2009-11-24 | 2010-08-25 | 姜世民 | Biological sample single-culture-medium separation culture apparatus |
| CN103599670A (en) * | 2013-12-03 | 2014-02-26 | 依贝伽射线防护设备科技（上海）有限公司 | Adsorption and filtration apparatus for iodine-131 radioisotope |
| CN203688278U (en) * | 2013-11-29 | 2014-07-02 | 武汉迪艾斯科技有限公司 | Stirring sampling device |
-
2015
- 2015-01-19 CN CN201510025202.6A patent/CN104560692B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2799572Y (en) * | 2005-06-16 | 2006-07-26 | 姜世民 | Automatic separation and culturing device for biological sample |
| CN201099684Y (en) * | 2007-08-31 | 2008-08-13 | 姜世民 | Biological specimen four sides isolated culture device |
| CN201560183U (en) * | 2009-11-24 | 2010-08-25 | 姜世民 | Biological sample single-culture-medium separation culture apparatus |
| CN203688278U (en) * | 2013-11-29 | 2014-07-02 | 武汉迪艾斯科技有限公司 | Stirring sampling device |
| CN103599670A (en) * | 2013-12-03 | 2014-02-26 | 依贝伽射线防护设备科技（上海）有限公司 | Adsorption and filtration apparatus for iodine-131 radioisotope |
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| Publication number | Publication date |
|---|---|
| CN104560692A (en) | 2015-04-29 |
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