Detailed description of the invention
Should be appreciated that specific embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.
The invention provides the early stage electro physiology detection method of a kind of chronic disease.
With reference to the schematic flow sheet that Fig. 1, Fig. 1 are chronic disease of the present invention early stage electro physiology detection method first embodiment.
In one embodiment, the early stage electro physiology detection method of chronic disease comprises:
Step S10, according to the project that the early stage electro physiology of chronic disease detects, calibration measurements position;
Step S20, arranges multiple electrode in the measuring point demarcated;
The present embodiment adopts the method measuring human body impedance value, can to such as diabetes earlier detection, cardiovascular and cerebrovascular disease earlier detection, and the earlier detection of other chronic diseases carries out measuring and examination.When carrying out electro physiology to gauger and detecting, first according to the project that the early stage electro physiology of chronic disease detects, calibration measurements position on the health of gauger, all corresponding calibration value in each measuring point; When Infrared irradiation predetermined patterns, because the absorbance of infrared light is with the thickness direct proportionality of tissue, so in the application of reality measures, need to demarcate the measurement point position at user preset position in advance, during to ensure to measure at every turn, the same ad-hoc location of irradiation in the measuring point preset of infrared light, concrete timing signal, the Infrared irradiation measuring point of certain wavelength can be adopted, measure measuring point to the absorbance E of the infrared light of current wavelength
0, this value is stored, and the calibration value using this value as measured measuring point.Demarcated after corresponding to the measuring point of the early stage electro physiology test item of different chronic disease, arrange multiple electrode in the measuring point demarcated, each measuring point all arranges an electrode.
Step S20, adopts the measuring-signal of different frequency, according to the combination of preset human body resistance network, measures the resistance value between the electrode often organizing measuring point corresponding to human body resistance network;
For the early stage electro physiology test item of different chronic diseases, in advance each measuring point demarcated is combined, form the combination of corresponding human body resistance network, when measuring, adopt the measuring-signal of different frequency, resistance value between the electrode measuring measuring point corresponding to each group human body resistance network of being formed respectively, obtains resistance value at different frequencies.By the determination that measuring point and measuring resistance combine, the all sites that pathological changes may occur that any one chronic disease early stage electro physiology test item is corresponding can be measured, find each chronic disease early stage electro physiology test item early lesion position more accurately to facilitate.
Step S30, according to the variable quantity of the resistance value between the electrode of measuring point corresponding to human body resistance network under the different frequency measured, according to preset examination criteria, determines and shows the result that electro physiology detects.
After resistance value between the electrode often organizing measuring point corresponding to human body resistance network under the measurement of human body resistance network obtains different frequency is organized to each, analyze the variable quantity of the resistance value between the electrode often organizing measuring point corresponding to human body resistance network, and according to the examination criteria by the preset correspondence of each chronic disease early stage electro physiology test item, judge whether the variable quantity of resistance value meets this examination criteria.Finally determine that whether the electro physiology testing result of gauger is normal according to the variable quantity of resistance value, and the result that electro physiology detects is shown to user, to point out the electro physiology testing result of this gauger of user for normal or abnormal.
The present embodiment is according to the early stage electro physiology test item of different chronic diseases, demarcate corresponding measuring point, and multiple electrode is set in measuring point, adopt the measuring-signal of different frequency, according to the combination of preset human body resistance network, measure the resistance value between the electrode often organizing measuring point corresponding to human body resistance network, and according to the variable quantity of the resistance value between the electrode of measuring point corresponding to human body resistance network under the different frequency measured, according to preset examination criteria, determine and show electro physiology detect result.Without the need to setting up human body resistance model, adopt multi-group electrode to measuring resistance value corresponding to many group human body resistance networks, the health pathological changes situation that the early stage electro physiology test item of different chronic disease may exist is measured by the conversion of resistance value, can measure the systemic pathological changes of body local or health condition targetedly, the result that the early stage electro physiology of chronic disease is detected is more accurate; And owing to moving in a large number before measuring without the need to gauger, thus measure efficiency higher.
Be determine in Fig. 1 and show the refinement schematic flow sheet of the step of the result that the early stage electro physiology of chronic disease detects with reference to Fig. 2, Fig. 2.
Based on the above embodiment of the present invention, step S40 specifically comprises:
Step S41, the variable quantity of the resistance value between the electrode often organizing measuring point corresponding to human body resistance network that analysis records at different frequencies;
Step S42, judges whether the change of the resistance value often organized between the electrode of measuring point corresponding to human body resistance network all meets preset examination criteria; If so, step S43 is performed; If not, step S44 is performed;
Step S43, determines that electro physiology testing result is normal, and shows normal outcome;
Step S44, display abnormal results and information.
After resistance value between the electrode recording under different frequency measuring point corresponding to each group human body resistance network, respectively the variable quantity of the resistance value between the electrode of measuring point corresponding to each group human body resistance network is analyzed.Then, according to preset examination criteria, judge whether the change of the resistance value often organized between the electrode of measuring point corresponding to human body resistance network all meets this examination criteria, this examination criteria the experimental data of early stage electro physiology test item when concrete measurement and experimental result can be determined according to different chronic diseases.When the variable quantity of the resistance value in the present embodiment between the electrode that each measurement organizes measuring point corresponding to human body resistance network all meets examination criteria, then determine that the result that this gauger's electro physiology detects is normal, now show normal outcome to user; The variable quantity of the resistance value between the electrode of at least one group of corresponding measuring point is had not meet examination criteria as in everyone the bulk resistor network measured, then show the results abnormity that electro physiology detects, now, abnormal results is shown to user, and hospital can be able to be gone to check to the form prompting user sending information, or the disease risks that prompting user may exist.
Further, based on above-described embodiment, resistance value between the electrode measuring measuring point corresponding to each group human body resistance network of obtaining gauger, and after determining according to the change quantitative analysis of resistance value at different frequencies the result that electro physiology detects, also by communication module, utilize WIFI, bluetooth and the mode such as infrared that the result that the data of measurement and electro physiology detect is sent to the service platforms such as network hospital.By this platform, hospital doctor according to the data received and result, can be diagnosed gauger further.Such as, be the suggestion that normal people provides the aspects such as diet, motion and life style to testing result, be back to user by information or other interactive modes by platform; Or, data for the gauger that there is chronic disease risk corresponding to the chronic disease early stage electro physiology test item that detects are further analyzed, this gauger is made a definite diagnosis, and by the suggestion of the aspects such as diagnostic result and diet, motion and life style, be back to user by information or other interactive modes by platform; Or, though for there is not chronic disease risk corresponding to detected chronic disease early stage electro physiology test item, but the variable quantity of resistance value measured under other people bulk resistor network does not meet preset examination criteria, doctor can for the data of exception, its other diseases that may exist of further analysis is also diagnosed, and then diagnostic result and other points for attention is back to user by information or other interactive modes by platform.
With reference to the schematic flow sheet that Fig. 3, Fig. 3 are chronic disease of the present invention early stage electro physiology detection method second embodiment.
On the basis of the invention described above chronic disease early stage electro physiology detection method first embodiment, in the second embodiment, before execution step S20, the method also comprises:
Step S50, adopts many group current measuring points of Infrared irradiation, compares the calibration value of measured value and the measuring point obtained;
Step S51, determines current measuring point according to preset range of error, makes the current measuring point determined and measuring point at same position.
In the present embodiment, before the resistance value between the electrode measuring measuring point corresponding to human body resistance network each time, one-time positioning can be carried out to measuring point.Namely many current selected measuring points of group Infrared irradiation are adopted, and compare according to the calibration value measuring measured value and the corresponding preset measuring point obtained, when the difference of measured value and calibration value is in preset range of error, then can determine that current measuring point and the preset measuring point selected are at same position, can to measuring at pre-test position when measuring.
As the preferred embodiment of the present embodiment, the current measuring point of the Infrared irradiation of two groups of phase co-wavelengths can be selected, concrete Wavelength-selective scope is the current measuring point of Infrared irradiation of 1000nm ~ 1200nm, wavelength is that the infrared light of 1200nm can penetrate human skeleton tissue, comparatively responsive to position, position is different, and the data recorded are also different.The infrared light of the preferred two groups of 1200nm of the present embodiment irradiates, and measures the current absorbance E of current measuring point to described two groups of infrared lights
1, E
2, and, preset range of error is set to 5%, namely as the measured value E that two groups of current measuring points of Infrared irradiation obtain
1, E
2with calibration value E
0difference all in the scope of 5% time, then judge that current measuring point is identical with the measuring point of demarcation; Difference as measured value and calibration value has one not in the scope of 5%, then change the position of current measuring point, until the difference of the measured value recorded and calibration value is all in the scope of 5%.
Adopt many group current measuring points of Infrared irradiation, according to the comparative result of the calibration value of measured value and measuring point, determine current measuring point, make current measuring point and measuring point at same position, precise positioning is carried out to measuring point, thus further ensures the accuracy of the early stage electro physiology detection of chronic disease.
As the preferred embodiment of the present invention, for the early stage electro physiology test item of chronic disease for diabetes earlier detection, the measurement of the resistance value between the electrode of the demarcation of measuring point and two measuring points corresponding to human body resistance network is described.
When the project that the early stage electro physiology of chronic disease detects is diabetes earlier detection, in the present embodiment, according to many experiments and empirical value, determine that the measuring point demarcated is respectively: human body arranged on left and right sides is near the position of wrist tremulous pulse, human body arranged on left and right sides is near the position of foot's tremulous pulse, and the forward and backward side of human abdomen is near the position of pancreas; And electrode is with the form of electrode pair, in arranged on left and right sides, one pair of electrodes is set near the position of wrist tremulous pulse, in arranged on left and right sides, one pair of electrodes is set near the position of foot's tremulous pulse, near the position of pancreas, respectively one pair of electrodes is set in forward and backward abdominal part arranged on left and right sides.By the setting of above-mentioned measuring point, can measure and include all sites that pathological changes may occur diabetes in early days, especially by both sides, human abdomen forward and backward side, corresponding electrode is set near the diverse location of pancreas, measure pancreas position and the local electric resistance between different limbs, find diabetes early lesion position more accurately to facilitate.
In order to measure the health pathological changes situation of diabetes early stage patient more accurately, according to the combination of the 4 groups of electrode pair determination human body resistance networks arranged, determine 24 groups of human body resistance networks, the compound mode of concrete human body resistance network is as follows:
1) left side wrist is to left side foot, measures electrode and the left side resistance near the electrode of the position of foot tremulous pulse between of left side near wrist tremulous pulse;
2) left side wrist is to right side wrist, measures electrode and the right side resistance near the electrode of the position of foot tremulous pulse between of left side near wrist tremulous pulse;
3) left side wrist is to right side wrist, measures electrode and the right side resistance near the electrode of the position of wrist tremulous pulse between of left side near wrist tremulous pulse;
4) left side wrist is to left abdomen (front), measures electrode and the abdominal part front left side resistance near the electrode of the position of pancreas between of left side near wrist tremulous pulse;
5) left side wrist is to left abdomen (afterwards), measures electrode and the abdominal part rear left side resistance near the electrode of the position of pancreas between of left side near wrist tremulous pulse;
6) left side wrist is to right abdomen (front), measures the resistance of left side on the right of the electrode and abdominal part front of wrist tremulous pulse between the electrode of the position of pancreas;
7) left side wrist is to right abdomen (afterwards), measures the resistance of left side on the right of the electrode and abdominal part rear of wrist tremulous pulse between the electrode of the position of pancreas;
8) right side wrist is to left side foot, measures right side near the resistance between the electrode of wrist tremulous pulse and the electrode of the position of left side foot tremulous pulse;
9) right side wrist is to right side foot, measures right side near the resistance between the electrode of wrist tremulous pulse and the electrode of the position of right side foot tremulous pulse;
10) right side wrist is to left abdomen (front), measures electrode and the abdominal part front left side resistance near the electrode of the position of pancreas between of right side near wrist tremulous pulse;
11) right side wrist is to left abdomen (afterwards), measures electrode and the abdominal part rear left side resistance near the electrode of the position of pancreas between of right side near wrist tremulous pulse;
12) right side wrist is to right abdomen (front), measures the resistance of right side on the right of the electrode and abdominal part front of wrist tremulous pulse between the electrode of the position of pancreas;
13) right side wrist is to right abdomen (afterwards), measures the resistance of right side on the right of the electrode and abdominal part rear of wrist tremulous pulse between the electrode of the position of pancreas;
14) left abdomen (front) is to left abdomen (afterwards), measures electrode and the abdominal part rear left side resistance near the electrode of the position of pancreas between of the left side, abdominal part front near the position of pancreas;
15) right abdomen (front) is to right abdomen (afterwards), measures the resistance on the right of the electrode of the position of pancreas and abdominal part rear between the electrode of the position of pancreas on the right of abdominal part front;
16) left side foot is to left abdomen (front), measures electrode and the left side, the abdominal part front resistance between the electrode of the position of pancreas of the position of left side foot tremulous pulse;
17) left side foot is to left abdomen (afterwards), measures electrode and the left side, the abdominal part rear resistance between the electrode of the position of pancreas of the position of left side foot tremulous pulse;
18) left side foot is to right abdomen (front), measures the resistance between the electrode of the position of pancreas on the right of the electrode of the position of left side foot tremulous pulse and abdominal part front;
19) left side foot is to right abdomen (afterwards), the resistance between the electrode measuring the position of close pancreas on the right of the electrode of the position of left side foot tremulous pulse and abdominal part rear;
20) right side foot is to left abdomen (front), measures electrode and the left side, the abdominal part front resistance between the electrode of the position of pancreas of the position of right side foot tremulous pulse;
21) right side foot is to left abdomen (afterwards), measures electrode and the left side, the abdominal part rear resistance between the electrode of the position of pancreas of the position of right side foot tremulous pulse;
22) right side foot is to right abdomen (front), measures the resistance between the electrode of the position of pancreas on the right of the electrode of the position of right side foot tremulous pulse and abdominal part front;
23) right side foot is to right abdomen (afterwards), the resistance between the electrode measuring the position of close pancreas on the right of the electrode of the position of right side foot tremulous pulse and abdominal part rear;
24) left side foot is to right side foot, measures the resistance between the electrode of position of left side foot tremulous pulse and the electrode of the position of right side foot tremulous pulse.
When measuring, adopt the measuring-signal of three kinds of different frequencies, the resistance value between the electrode measuring two measuring points corresponding to above-mentioned 24 groups of human body resistance networks respectively, is often organized the resistance value of human body resistance network under three kinds of frequencies.By the determination that above-mentioned measuring point and measuring resistance combine, can measure and include all sites that pathological changes may occur diabetes in early days, especially by both sides, human abdomen forward and backward side, corresponding electrode is set near the diverse location of pancreas, measure pancreas position and the local electric resistance between different limbs, find diabetes early lesion position more accurately to facilitate.
In the present embodiment, preferred employing frequency is 50khz, 100khz, 3 ~ 5.5V sine wave alternating current of 150khz is compressed into row and is measured, drawn by clinical trial, be 50khz in frequency, 100khz, 3 ~ 5.5V sine wave alternating current pressure of 150khz, resistance value between the electrode of measuring point corresponding to each group human body resistance network is compared, the variable quantity calibration ordinary person of the resistance value of diabetes early stage patient wants large, especially 14), 15) change of resistance value more can reflect the pathological changes of diabetes early stage patient health, namely when human body resistance combination of network be left abdomen (front) to left abdomen (after), and right abdomen (front) to right abdomen (afterwards) time, the variable quantity of the resistance value between the electrode of the measuring point of the correspondence obtained more can reflect the pathological changes of diabetes early stage patient health, so just, by the change of the resistance value at local body position and the size of change magnitude of deviation, analyze and judge that the disease condition residing for patient is (early stage, mid-term and late period).
The present embodiment have chosen the experimenter of 40 Different age group to verify feasibility and the superiority of this programme when clinical trial, the age distribution of 40 bit test persons: be less than 30 years old be 5 people, 30 years old ~ within 40 years old, be 8 people, 40 years old ~ within 50 years old, be 12 people, 50 years old ~ within 60 years old, be 10 people, within more than 60 years old, be 5 people.Pass through said method, the change of the 24 group body local resistance values of all experimenters under above-mentioned three kinds of frequencies is analyzed, have chosen 4 people 14), 15) test data of the change of resistance value measured under human body resistance network, represent that diabetes are early stage respectively, mid-term, late period different sign information:
(1) Lee, 27 years old, normal person;
(2) Zhang, 36 years old, diabetes early stage patient;
(3) Zhao, 42 years old, diabetes patient in mid-term;
(4) field, 59 years old, advanced diabetes patient.
Following table be by 3 ~ 5.5V sine wave AC voltage of 50khz, 100khz, 150khz to above 4 people 14), 15) variable quantity of resistance value measured under human body resistance network:
Above-mentioned data only embody the situation of the human body impedance rate of change of 4 kinds of different crowds selected among 40 bit test persons, by testing according to the method for testing provided in this programme the experimenter of 40 Different age group and different health, obtain following rule:
1, normal person: under 50khz, 100khz, 150khz different frequency, 14), 15) rate of change of resistance value is below 0.5%;
2, diabetes early stage patient: under 50khz, 100khz, 150khz different frequency, 14), 15) rate of change of resistance value is 0.5% ~ 0.7%;
3, diabetes patient in mid-term: under 50khz, 100khz, 150khz different frequency, 14), 15) rate of change of resistance value is 0.65% ~ 1.0%;
4, advanced diabetes patient: under 50khz, 100khz, 150khz different frequency, 14), 15) rate of change of resistance value is more than 1.0%.
That is, except 14), 15) rate of change of resistance value is below 0.5%, the rate of change of resistance value measured under other 22 groups of human body resistance networks, also below 0.5%, just can judge that the result of the diabetes earlier detection of this gauger is normal; As 14), 15) rate of change of resistance value is more than 0.5%, then judge the stage residing for this gauger further according to the value of concrete rate of change, now, show abnormal results to user and point out user to be likely in which of diabetes in stage, prompting user goes to hospital to make a definite diagnosis inspection further; As 14), 15) rate of change of resistance value is below 0.5%, and the rate of change of resistance value measured under other 22 groups of human body resistance networks has at least one group more than 0.5%, then show that other abnormal conditions likely appear in the health of this gauger, now, to user show this abnormal results and point out user its hospital can be gone to check further.
The present invention also provides a kind of chronic disease early stage electro physiology detection system.
With reference to the structural representation that Fig. 4, Fig. 4 are chronic disease of the present invention early stage electro physiology detection system first embodiment.
In one embodiment, the early stage electro physiology detection system of chronic disease comprises:
Demarcating module 10, for the project detected according to the early stage electro physiology of chronic disease, calibration measurements position;
Module 20 is set, for arranging multiple electrode in the measuring point demarcated;
Measurement module 30, for adopting the measuring-signal of different frequency, according to the combination of preset human body resistance network, measures the resistance value between the electrode often organizing measuring point corresponding to human body resistance network;
Determine and display module 40, for the variable quantity according to the resistance value between the electrode of measuring point corresponding to human body resistance network under the different frequency measured, according to preset examination criteria, determine and show the result that electro physiology detects.
The present embodiment adopts the method measuring human body impedance value, can to such as diabetes earlier detection, cardiovascular and cerebrovascular disease earlier detection, and the earlier detection of other chronic diseases carries out measuring and examination.When carrying out the early stage electro physiology of chronic disease to gauger and detecting, demarcating module 10 first according to the project that the early stage electro physiology of chronic disease detects, calibration measurements position on the health of gauger, all corresponding calibration value in each measuring point; When Infrared irradiation predetermined patterns, because the absorbance of infrared light is with the thickness direct proportionality of tissue, so in the application of reality measures, need to demarcate the measurement point position at user preset position in advance, during to ensure to measure at every turn, the same ad-hoc location of irradiation in the measuring point preset of infrared light, concrete timing signal, the Infrared irradiation measuring point of certain wavelength can be adopted, measure measuring point to the absorbance E of the infrared light of current wavelength
0, this value is stored, and the calibration value using this value as measured measuring point.Demarcated after corresponding to the measuring point of the early stage electro physiology test item of different chronic disease, arrange module 20 and arrange multiple electrode in the measuring point demarcated, each measuring point all arranges an electrode.
For the early stage electro physiology test item of different chronic diseases, in advance each measuring point demarcated is combined, form the combination of corresponding human body resistance network, when measuring, measurement module 30 adopts the measuring-signal of different frequency, resistance value between the electrode measuring measuring point corresponding to each group human body resistance network of being formed respectively, obtains resistance value at different frequencies.By the determination that measuring point and measuring resistance combine, the all sites that pathological changes may occur that any one chronic disease early stage electro physiology test item is corresponding can be measured, find each chronic disease early stage electro physiology test item early lesion position more accurately to facilitate.
After resistance value between the electrode often organizing measuring point corresponding to human body resistance network under the measurement of human body resistance network obtains different frequency is organized to each, to determine and display module 40 analyzes the variable quantity of the resistance value between the electrode often organizing measuring point corresponding to human body resistance network, and according to the examination criteria by the preset correspondence of each chronic disease early stage electro physiology test item, judge whether the variable quantity of resistance value meets this examination criteria.Finally determine that whether the electro physiology testing result of gauger is normal according to the variable quantity of resistance value, and the result that electro physiology detects is shown to user, to point out the electro physiology testing result of this gauger of user for normal or abnormal.
The present embodiment is according to the early stage electro physiology test item of different chronic diseases, demarcate corresponding measuring point, and multiple electrode is set in measuring point, adopt the measuring-signal of different frequency, according to the combination of preset human body resistance network, measure the resistance value between the electrode often organizing measuring point corresponding to human body resistance network, and according to the variable quantity of the resistance value between the electrode of measuring point corresponding to human body resistance network under the different frequency measured, according to preset examination criteria, determine and show electro physiology detect result.Without the need to setting up human body resistance model, adopt multi-group electrode to measuring resistance value corresponding to many group human body resistance networks, the health pathological changes situation that the early stage electro physiology test item of different chronic disease may exist is measured by the conversion of resistance value, can measure the systemic pathological changes of body local or health condition targetedly, the result that the early stage electro physiology of chronic disease is detected is more accurate; And owing to moving in a large number before measuring without the need to gauger, thus measure efficiency higher.
In the above-described embodiments, determine and display module 40 specifically for:
The variable quantity of the resistance value between the electrode often organizing measuring point corresponding to human body resistance network that analysis records at different frequencies;
Judge whether the change of the resistance value often organized between the electrode of measuring point corresponding to human body resistance network all meets preset examination criteria; If so, determine that electro physiology testing result is normal, and show normal outcome; If not, abnormal results and information is shown.
After resistance value between the electrode recording under different frequency measuring point corresponding to each group human body resistance network, to determine and display module 40 is analyzed the variable quantity of the resistance value between the electrode of measuring point corresponding to each group human body resistance network respectively.Then, according to preset examination criteria, judge whether the change of the resistance value often organized between the electrode of measuring point corresponding to human body resistance network all meets this examination criteria, this examination criteria the experimental data of early stage electro physiology test item when concrete measurement and experimental result can be determined according to different chronic diseases.When the variable quantity of the resistance value in the present embodiment between the electrode that each measurement organizes measuring point corresponding to human body resistance network all meets examination criteria, then determine that the result that this gauger's electro physiology detects is normal, now to determine and display module 40 shows normal outcome to user; The variable quantity of the resistance value between the electrode of at least one group of corresponding measuring point is had not meet examination criteria as in everyone the bulk resistor network measured, then show the results abnormity that electro physiology detects, now, to determine and display module 40 shows abnormal results to user, and hospital can be able to be gone to check to the form prompting user sending information, or the disease risks that prompting user may exist.
Further, based on above-described embodiment, resistance value between the electrode measuring measuring point corresponding to each group human body resistance network of obtaining gauger, and after determining according to the change quantitative analysis of resistance value at different frequencies the result that electro physiology detects, also by communication module, utilize WIFI, bluetooth and the mode such as infrared that the result that the data of measurement and electro physiology detect is sent to the service platforms such as network hospital.By this platform, hospital doctor according to the data received and result, can be diagnosed gauger further.Such as, be the suggestion that normal people provides the aspects such as diet, motion and life style to testing result, be back to user by information or other interactive modes by platform; Or, data for the gauger that there is chronic disease risk corresponding to the chronic disease early stage electro physiology test item that detects are further analyzed, this gauger is made a definite diagnosis, and by the suggestion of the aspects such as diagnostic result and diet, motion and life style, be back to user by information or other interactive modes by platform; Or, though for there is not chronic disease risk corresponding to detected chronic disease early stage electro physiology test item, but the variable quantity of resistance value measured under other people bulk resistor network does not meet preset examination criteria, doctor can for the data of exception, its other diseases that may exist of further analysis is also diagnosed, and then diagnostic result and other points for attention is back to user by information or other interactive modes by platform.
With reference to the structural representation that Fig. 5, Fig. 5 are chronic disease of the present invention early stage electro physiology detection system second embodiment.
Based on the invention described above chronic disease early stage electro physiology detection system first embodiment, in the second embodiment, this system also comprises locating module 50, this locating module 50 for:
Adopt many group current measuring points of Infrared irradiation, compare the calibration value of measured value and the measuring point obtained;
Determine current measuring point according to preset range of error, make the current measuring point determined and measuring point at same position.
In the present embodiment, before the resistance value between the electrode measuring measuring point corresponding to human body resistance network each time, locating module 50 can carry out one-time positioning to measuring point.Namely many current selected measuring points of group Infrared irradiation are adopted, and compare according to the calibration value measuring measured value and the corresponding preset measuring point obtained, when the difference of measured value and calibration value is in preset range of error, then can determine that current measuring point and the preset measuring point selected are at same position, can to measuring at pre-test position when measuring.
As the preferred embodiment of the present embodiment, the current measuring point of the Infrared irradiation of two groups of phase co-wavelengths can be selected, concrete Wavelength-selective scope is the current measuring point of Infrared irradiation of 1000nm ~ 1200nm, wavelength is that the infrared light of 1200nm can penetrate human skeleton tissue, comparatively responsive to position, position is different, and the data recorded are also different.The infrared light of the preferred two groups of 1200nm of the present embodiment irradiates, and measures the current absorbance E of current measuring point to described two groups of infrared lights
1, E
2, and, preset range of error is set to 5%, namely as the measured value E that two groups of current measuring points of Infrared irradiation obtain
1, E
2with calibration value E
0difference all in the scope of 5% time, then judge that current measuring point is identical with the measuring point of demarcation; Difference as measured value and calibration value has one not in the scope of 5%, then change the position of current measuring point, until the difference of the measured value recorded and calibration value is all in the scope of 5%.
Adopt many group current measuring points of Infrared irradiation, according to the comparative result of the calibration value of measured value and measuring point, determine current measuring point, make current measuring point and measuring point at same position, precise positioning is carried out to measuring point, thus further ensures the accuracy of the early stage electro physiology detection of chronic disease.
As the preferred embodiment of the present invention, for the early stage electro physiology test item of chronic disease for diabetes earlier detection, the measurement of the resistance value between the electrode of the demarcation of measuring point and two measuring points corresponding to human body resistance network is described.
When the project that the early stage electro physiology of chronic disease detects is diabetes earlier detection, in the present embodiment, according to many experiments and empirical value, determine that the measuring point demarcated is respectively: human body arranged on left and right sides is near the position of wrist tremulous pulse, human body arranged on left and right sides is near the position of foot's tremulous pulse, and the forward and backward side of human abdomen is near the position of pancreas; And electrode is with the form of electrode pair, in arranged on left and right sides, one pair of electrodes is set near the position of wrist tremulous pulse, in arranged on left and right sides, one pair of electrodes is set near the position of foot's tremulous pulse, near the position of pancreas, respectively one pair of electrodes is set in forward and backward abdominal part arranged on left and right sides.By the setting of above-mentioned measuring point, can measure and include all sites that pathological changes may occur diabetes in early days, especially by both sides, human abdomen forward and backward side, corresponding electrode is set near the diverse location of pancreas, measure pancreas position and the local electric resistance between different limbs, find diabetes early lesion position more accurately to facilitate.
In order to measure the health pathological changes situation of diabetes early stage patient more accurately, according to the combination of the 4 groups of electrode pair determination human body resistance networks arranged, determine 24 groups of human body resistance networks, the compound mode of concrete human body resistance network is as follows:
1) left side wrist is to left side foot, measures electrode and the left side resistance near the electrode of the position of foot tremulous pulse between of left side near wrist tremulous pulse;
2) left side wrist is to right side wrist, measures electrode and the right side resistance near the electrode of the position of foot tremulous pulse between of left side near wrist tremulous pulse;
3) left side wrist is to right side wrist, measures electrode and the right side resistance near the electrode of the position of wrist tremulous pulse between of left side near wrist tremulous pulse;
4) left side wrist is to left abdomen (front), measures electrode and the abdominal part front left side resistance near the electrode of the position of pancreas between of left side near wrist tremulous pulse;
5) left side wrist is to left abdomen (afterwards), measures electrode and the abdominal part rear left side resistance near the electrode of the position of pancreas between of left side near wrist tremulous pulse;
6) left side wrist is to right abdomen (front), measures the resistance of left side on the right of the electrode and abdominal part front of wrist tremulous pulse between the electrode of the position of pancreas;
7) left side wrist is to right abdomen (afterwards), measures the resistance of left side on the right of the electrode and abdominal part rear of wrist tremulous pulse between the electrode of the position of pancreas;
8) right side wrist is to left side foot, measures right side near the resistance between the electrode of wrist tremulous pulse and the electrode of the position of left side foot tremulous pulse;
9) right side wrist is to right side foot, measures right side near the resistance between the electrode of wrist tremulous pulse and the electrode of the position of right side foot tremulous pulse;
10) right side wrist is to left abdomen (front), measures electrode and the abdominal part front left side resistance near the electrode of the position of pancreas between of right side near wrist tremulous pulse;
11) right side wrist is to left abdomen (afterwards), measures electrode and the abdominal part rear left side resistance near the electrode of the position of pancreas between of right side near wrist tremulous pulse;
12) right side wrist is to right abdomen (front), measures the resistance of right side on the right of the electrode and abdominal part front of wrist tremulous pulse between the electrode of the position of pancreas;
13) right side wrist is to right abdomen (afterwards), measures the resistance of right side on the right of the electrode and abdominal part rear of wrist tremulous pulse between the electrode of the position of pancreas;
14) left abdomen (front) is to left abdomen (afterwards), measures electrode and the abdominal part rear left side resistance near the electrode of the position of pancreas between of the left side, abdominal part front near the position of pancreas;
15) right abdomen (front) is to right abdomen (afterwards), measures the resistance on the right of the electrode of the position of pancreas and abdominal part rear between the electrode of the position of pancreas on the right of abdominal part front;
16) left side foot is to left abdomen (front), measures electrode and the left side, the abdominal part front resistance between the electrode of the position of pancreas of the position of left side foot tremulous pulse;
17) left side foot is to left abdomen (afterwards), measures electrode and the left side, the abdominal part rear resistance between the electrode of the position of pancreas of the position of left side foot tremulous pulse;
18) left side foot is to right abdomen (front), measures the resistance between the electrode of the position of pancreas on the right of the electrode of the position of left side foot tremulous pulse and abdominal part front;
19) left side foot is to right abdomen (afterwards), the resistance between the electrode measuring the position of close pancreas on the right of the electrode of the position of left side foot tremulous pulse and abdominal part rear;
20) right side foot is to left abdomen (front), measures electrode and the left side, the abdominal part front resistance between the electrode of the position of pancreas of the position of right side foot tremulous pulse;
21) right side foot is to left abdomen (afterwards), measures electrode and the left side, the abdominal part rear resistance between the electrode of the position of pancreas of the position of right side foot tremulous pulse;
22) right side foot is to right abdomen (front), measures the resistance between the electrode of the position of pancreas on the right of the electrode of the position of right side foot tremulous pulse and abdominal part front;
23) right side foot is to right abdomen (afterwards), the resistance between the electrode measuring the position of close pancreas on the right of the electrode of the position of right side foot tremulous pulse and abdominal part rear;
24) left side foot is to right side foot, measures the resistance between the electrode of position of left side foot tremulous pulse and the electrode of the position of right side foot tremulous pulse.
When measuring, adopt the measuring-signal of three kinds of different frequencies, the resistance value between the electrode measuring two measuring points corresponding to above-mentioned 24 groups of human body resistance networks respectively, is often organized the resistance value of human body resistance network under three kinds of frequencies.By the determination that above-mentioned measuring point and measuring resistance combine, can measure and include all sites that pathological changes may occur diabetes in early days, especially by both sides, human abdomen forward and backward side, corresponding electrode is set near the diverse location of pancreas, measure pancreas position and the local electric resistance between different limbs, find diabetes early lesion position more accurately to facilitate.
In the present embodiment, preferred employing frequency is 50khz, 100khz, 3 ~ 5.5V sine wave alternating current of 150khz is compressed into row and is measured, drawn by clinical trial, be 50khz in frequency, 100khz, 3 ~ 5.5V sine wave alternating current pressure of 150khz, resistance value between the electrode of measuring point corresponding to each group human body resistance network is compared, the variable quantity calibration ordinary person of the resistance value of diabetes early stage patient wants large, especially 14), 15) change of resistance value more can reflect the pathological changes of diabetes early stage patient health, namely when human body resistance combination of network be left abdomen (front) to left abdomen (after), and right abdomen (front) to right abdomen (afterwards) time, the variable quantity of the resistance value between the electrode of the measuring point of the correspondence obtained more can reflect the pathological changes of diabetes early stage patient health, so just, by the change of the resistance value at local body position and the size of change magnitude of deviation, analyze and judge that the disease condition residing for patient is (early stage, mid-term and late period).
The present embodiment have chosen the experimenter of 40 Different age group to verify feasibility and the superiority of this programme when clinical trial, the age distribution of 40 bit test persons: be less than 30 years old be 5 people, 30 years old ~ within 40 years old, be 8 people, 40 years old ~ within 50 years old, be 12 people, 50 years old ~ within 60 years old, be 10 people, within more than 60 years old, be 5 people.Pass through said method, the change of the 24 group body local resistance values of all experimenters under above-mentioned three kinds of frequencies is analyzed, have chosen 4 people 14), 15) test data of the change of resistance value measured under human body resistance network, represent that diabetes are early stage respectively, mid-term, late period different sign information:
(1) Lee, 27 years old, normal person;
(2) Zhang, 36 years old, diabetes early stage patient;
(3) Zhao, 42 years old, diabetes patient in mid-term;
(4) field, 59 years old, advanced diabetes patient.
Following table be by 3 ~ 5.5V sine wave AC voltage of 50khz, 100khz, 150khz to above 4 people 14), 15) variable quantity of resistance value measured under human body resistance network:
Above-mentioned data only embody the situation of the human body impedance rate of change of 4 kinds of different crowds selected among 40 bit test persons, by testing according to the method for testing provided in this programme the experimenter of 40 Different age group and different health, obtain following rule:
1, normal person: under 50khz, 100khz, 150khz different frequency, 14), 15) rate of change of resistance value is below 0.5%;
2, diabetes early stage patient: under 50khz, 100khz, 150khz different frequency, 14), 15) rate of change of resistance value is 0.5% ~ 0.7%;
3, diabetes patient in mid-term: under 50khz, 100khz, 150khz different frequency, 14), 15) rate of change of resistance value is 0.65% ~ 1.0%;
4, advanced diabetes patient: under 50khz, 100khz, 150khz different frequency, 14), 15) rate of change of resistance value is more than 1.0%.
That is, except 14), 15) rate of change of resistance value is below 0.5%, the rate of change of resistance value measured under other 22 groups of human body resistance networks, also below 0.5%, just can judge that the result of the diabetes earlier detection of this gauger is normal; As 14), 15) rate of change of resistance value is more than 0.5%, then judge the stage residing for this gauger further according to the value of concrete rate of change, now, show abnormal results to user and point out user to be likely in which of diabetes in stage, prompting user goes to hospital to make a definite diagnosis inspection further; As 14), 15) rate of change of resistance value is below 0.5%, and the rate of change of resistance value measured under other 22 groups of human body resistance networks has at least one group more than 0.5%, then show that other abnormal conditions likely appear in the health of this gauger, now, to user show this abnormal results and point out user its hospital can be gone to check further.
These are only the preferred embodiments of the present invention; not thereby the scope of the claims of the present invention is limited; every utilize description of the present invention and accompanying drawing content to do equivalent structure or equivalent flow process conversion; or be directly or indirectly used in other relevant technical fields, be all in like manner included in scope of patent protection of the present invention.