CN104545895B - Method for quickly screening out drug addicts by electroencephalogram characteristics - Google Patents
Method for quickly screening out drug addicts by electroencephalogram characteristics Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/369—Electroencephalography [EEG]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7271—Specific aspects of physiological measurement analysis
- A61B5/7282—Event detection, e.g. detecting unique waveforms indicative of a medical condition
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Abstract
The invention discloses a method for quickly screening out drug addicts by electroencephalogram characteristics. An electroencephalogram detection technology is utilized, and suspects who take drugs can be quickly screened out according to the electroencephalogram characteristics of reaction on illumination and light removal of people which are detected. The detection method for quickly screening out the drug addicts has the advantages of convenience in operation, high speed and accuracy in obtaining results and good accuracy and practicality.
Description
Technical field
The present invention relates to a kind of detection method of the brain electrical feature rapid screening drug addict according to detected person.
Background technology
Rapid screening drug abuse suspect is one of important content of social banning drugs work.China is to drug abuse suspect's at present
Examination is based primarily upon the biochemical studies to detected person's urine or blood.Traditional urine test paper has easy to use, pin
The characteristic such as strong to property, but expensive, the shelf-life is shorter, can not for multiple (two or more) illicit drugs inspection, using rear arbitrarily
Process the problem not environmentally and being easily subject to the interference such as diet, medicine.When extracting tested humoral sample urine sample or blood sample to operation
Accuracy requirement height is and it needs to carry out special training to technical staff.And, due to carrying various viruses in drug addict
Ratio is very high, increased the probability that basic unit police and technical staff are infected by multiple viruses in the processing procedure of body fluid.Separately
Outward, for dysuria, need the doubtful junkie waiting as long for detection when, urine examination be compared difficulty.Furthermore, in public affairs
When altogether especially highway is enforced the drug law in place, the detection method such as urine examination exists awkward.
Therefore, in recent years substantial amounts of research has been carried out to the drug addict's screening method being not required to extract detected person's body fluid.
Chinese patent cn201110452819.8 proposes a kind of detection method identifying identification drug addict by mobile phone pupil, the party
Method is scanned using the pupil state under the ordinary light state to detected person for the photographic head of mobile phone, to obtain pupil feature figure
Picture.Obtain pupil size characteristic information and eye dimension information followed by the pupil feature image obtaining, and the ratio with both
Value is compared with empirical value, if this ratio is less than empirical value, judges detected person as drug addict.But in the disclosure of this patent
Rong Zhong, does not refer to how obtaining this empirical value and the specific span of this empirical value.And, the method is not related to quilt
The dynamic detection of tester's pupil change.
Chinese patent cn200510048618.6 propose a kind of quick discriminating opium drug drug addict's addiction and its
The method of degree of dependence.Instill in the eye of detected person with the eye drop of opiate receptor pure antagonist naloxone, relatively more detected
Pupil diameter before eye drip and after eye drip 10-40 minute for the person, if difference is more than 5 pixels, judges detected person as suction
Malicious personnel.But due to pupil diameter account for image pixel size relevant with the resolution of image acquisition equipment, therefore pupil before and after eye drip
The pixel value difference of bore dia is also relevant with the resolution of image acquisition equipment.And in the disclosure of which, do not refer to that measurement should
The parameter of the image acquisition equipment of pupil diameter, therefore those skilled in the art is actual cannot use the method disclosure of that
Carry out the discriminating to drug addict and examination.And, the method for this patent is detected there is limitation just for opium drug
Property, and the method needs consuming medicine naloxone just to enable the dynamic detection to the change of testee's pupil.
Present invention applicant in order to overcome the defect of the detection method of above examination drug addict, in Chinese patent
Propose in cn200410079526.x a kind of method of utilization drug addict pupillary movements quick detection drug addict and
Its device.In this detection method and its device, using infrared light sources and infrared camera, the pupil of testee is changed,
The frequency of ocular movement and nictation is detected, and the pupil disclosing under the dark adaptation comparing 2 minutes dynamically and opens polished bard
Swash the pupillary movements in 1 minute, to differentiate the method whether testee sucks heroin.This method propose according to flat
By pupillary movements, the pupil empirical value often recording, relatively to differentiate whether suspect takes drugs.But the method must be in advance
Get the usual pupil size of the non-kif of suspect.And basic unit police is when setting out to be enforced the drug law, acquisition of not having ready conditions
The usual pupil size of the non-kif of suspect, therefore the method are difficult in drug law enforcement action to checked suspicion for the first time
People uses.Although and, this patent indicates that the method can also obtain the data of pupillary movements before and after photostimulation, simultaneously
Do not explicitly point out using the method for pupillary movements examination drug addict and criterion before and after photostimulation.And the skill of this area
Art personnel understand, before and after the photostimulation in other words of this criterion the span of pupillary movements difference value be judge tested
The important indicator of person whether drug addict.
Content of the invention
For the problems of prior art, the present invention proposes a kind of brain electrical feature of utilization detected person and quickly sieves
Look into the detection method of drug abuse suspicion personnel.
The invention provides a kind of electroencephalogram power spectrum signature using detected person is come rapid screening drug abuse suspicion personnel's
Detection method, comprising: after the fixing duration of dark adaptation one, gives detected person one illumination of fixing duration, then blacks out and tie up
Hold a set time, in the entirely interval of above-mentioned dark adaptation-illumination-black out it is desirable to testee is whole closes one's eyes or open eyes, and point
Not Ce Liang detected person close one's eyes when and open eyes when EEG power spectrum；Judge 30hz and 42.5hz of described electroencephalogram power spectral curve
Whether place is with the presence or absence of the peak having at crest, and 42.5hz higher than the peak at 30hz；If 30hz and
There are the peak that the peak at crest, and 42.5hz is higher than at 30hz at 42.5hz, then judge detected person pole
It is possible to as drug abuse suspect.
The detection method of the rapid screening drug addict of the present invention, is not related to testee's blood due to during using
Or the extraction of the body fluid such as urine sample, so improve the simplicity of operation, it is to avoid the inconvenience of urine sample is checked in public place；Detection
The procedure time is short, obtains result quickly also accurately, decreases complicated operation in urine examination program etc. and waiting time；
And do not need to expend medicine, greatly save cost, there is good economic benefit, and there is good accuracy and reality
The property used；The criterion of quicklook can be provided in basic unit police examination drug abuse suspect.
Brief description
Fig. 1, Fig. 2 and Fig. 3 are respectively the EEG power spectrum curve control figure of three different drug abuse suspects and normal person.
Specific embodiment
The present invention provide a kind of using EEG power spectrum characteristic index come the method for examination drug addict, and be used in combination
EEG power spectrum characteristic index and pupillary movements index carry out the detection method of rapid screening drug abuse suspicion personnel, thus being
Examination is detected whether personnel are determination methods and the standard that drug abuse suspect provides quicklook.
Alleged drug abuse suspicion in the present invention is artificial on evidence (e.g., biochemistry detection evidence or other similar credible evidences etc.)
Show that it has the people sucking dependence producing drug (e.g., heroin, methamphetamine hydrochloride, the k powder etc.) behavior that country prohibites.
The present invention relates to the brain electrical feature of collection and analysis detected person, including the brain electric work of collection and analysis detected person
Rate is composed.EEG power spectrum represents the distribution situation of electrical energy of brain, can show the change situation of EEG signals power with frequency.
Using EEG power spectrum analysis method, it is obtained in that the frequency of the high signal of energy in EEG signals.
In the present invention, the collection of EEG power spectrum and analysis by technical staff use this area common tool, according to
The conventional method of this area is realizing.In one particular embodiment of the present invention, the brain wave acquisition part tool that the present invention uses
There are a Grounding, a reference channel and several brain electric channels and analogue amplifier amplification more than 800, band logical
Filtering 0.5～150hz, 50hz and 100hz trap, EEG signals numeralization collecting device (analog digital conversion plate, ad plate) sampling frequency
Rate 1000hz, precision more than 12.
The invention still further relates to giving detected person illumination.Give the situation of illumination by those skilled in the art conventionally,
Realized using conventional meanses.In one particular embodiment of the present invention, give detected person's eyes illumination be set to uniformly,
Soft white light.The persistent period of illumination can be adjusted according to invention needs, can from less than 1 second to the several seconds to tens of seconds
To several minutes to several tens minutes.In one particular embodiment of the present invention, preferably give the light stimulation of 2 seconds durations.
In the present invention, described light stimulation part, brain wave acquisition part are all connected to an acquisition terminal.This acquisition terminal is used
To control each part mentioned above hardware collaborative work, send optical stimulus signal, collection EEG signals, finally calculating process collects
According to the determination methods that the present invention provides, signal simultaneously finally judges whether detected person is drug abuse suspect.These information can be
It is shown in eventually on the display screen that this terminal has.This acquisition terminal is responsible for organizing above-mentioned each hardware according to phase using control software
The time serieses answered send stimulation and collection signal, and calculate and provide judged result.This control software needs to organize different
Software module is completing above-mentioned work.
Brain wave acquisition and spectrum calculation resume module that the multichannel brain signal of telecommunication is commonly used by those skilled in the art.Processed
Cheng Zhong, carries out spectra calculation respectively by each passage of the multichannel brain signal of telecommunication that ad plate is collected, the result transmission obtaining
To judge module.
After brain electricity judge module receives the information that brain wave acquisition and spectrum calculation module transmit, provided using the present invention
Evaluation algorithm carries out to EEG power spectrum calculating and judges, thus showing that whether detected person is the result of drug abuse suspect.
Applicant of the present invention, according to many experiments, finds to be judged according to the electroencephalogram power spectrum signature of detected person
Whether detected person is drug abuse suspect, and the order of accuarcy of described judgement is sufficient for rapid screening in practice and is accused of drug abuse
The needs of personnel.
According to a specific embodiment of the present invention, after allowing detected person's dark adaptation one fix duration, give one solid
The long illumination of timing, then black out and keep necessarily fixing duration；Comprise the complete of the dark adaptation-illumination-three phases that black out at this
It is desirable to detected person or be always maintained at opening eyes in whole period, or be always maintained at closing one's eyes, respectively measurement detected person close one's eyes and
EEG power spectrum during eye opening.According to another specific embodiment of the present invention, described eye opening is with eye closing separately.According to this
Invent another specific embodiment, the measurement of EEG power spectrum may require that detected person opens eyes respectively and closes one's eyes 2 times or 2 times
More than, such as 3 times, 4 times, 5 times, 7 inferior, and correspondingly average with obtain detected person open eyes and the stage of closing one's eyes brain
Electrical power is composed.
Preferably, a length of 30 seconds or longer when scotopic, light irradiation time is 2 seconds, a length of 2 seconds or longer when after blacking out.
According to an embodiment of the invention, need to judge the aforementioned electroencephalogram power spectral curve that recorded in 30hz and
Whether there is at 42.5hz has crest；And, the crest at 42.5hz peak value whether higher than the peak of the crest at 30hz
Value.Described crest refers to crest at 30hz and at 42.5hz and is in ± the 2.5hz of this frequency.
This electroencephalogram power spectral curve can be recorded when opening eyes it is also possible to recorded when closing one's eyes, electroencephalogram power
Spectrum can dark adaptation section recorded or arrive in area of illumination segment record, can also be in the section note that blacks out
Record.
According to the present invention, if the aforementioned electroencephalogram power spectral curve that recorded all there are ripple at 30hz and 42.5hz
Peak；And, it is higher than the peak value of the crest at 30hz it is possible to directly judge detected person in the peak value of the crest at 42.5hz
It is very likely drug abuse suspect.
[embodiment]
Drug abuse suspect is numbered as detected person, so that detected person is worn and there is above-mentioned brain wave acquisition part
Brain electrode cap, the scalp electrodes leading electroencephalograph with scalp electrode are attached on head more, detected person's eyes light by every
Absolutely, after adapting to half a minute in dark conditions, the equal white light giving 2 seconds durations irradiates, then blacks out and maintain 2 seconds.Tested
Survey person keeps closing one's eyes or keep to open eyes according to the requirement of testing staff in once complete test process.Close one's eyes and eye opening phase
Interval, after distinguishing in triplicate, detection of end.The signal that collects through with light source and lead the computer that electroencephalograph is connected more and carry out
It is shown on terminal display screen after calculating.Meanwhile, gather testee's urine, with reality in biochemical detection methods detection urine
Coffee content, the data after summarizing may refer to table 1.
Table 1:
As known from Table 1, if the electroencephalogram power spectral curve that recorded there are crest at 30hz and 42.5hz；And,
It is higher than peak at 30hz in the peak at 42.5hz, then detected person all shows in urine and has morphine and contain
Amount.
It should be noted that the announcement of book and teaching according to the above description, those skilled in the art in the invention also may be used
To be changed to above-mentioned embodiment and to be changed.Therefore, the invention is not limited in disclosed and described above being embodied as
Mode, in the scope of the claims that some modifications and changes of the present invention be should also be as fall into the present invention.Although additionally,
Employ some specific terms in this specification, but these terms are merely for convenience of description, the present invention is not constituted and appoint
What limits.
Claims (2)
1. a kind of detection method of rapid screening drug addict, comprises the steps of
A) after the fixing duration of dark adaptation one, when the maintenance one that blacks out again after the illumination giving the fixing duration of detected person one is fixed
Long it is desirable to testee is whole in this course opens eyes or close one's eyes, and when measurement detected person opens eyes respectively and the when of eye closing
EEG power spectrum；
B) judge described open eyes when or close one's eyes when measure 30hz and 42.5hz of EEG power spectrum place whether there is crest and
Whether the peak at 42.5hz is higher than the peak at 30hz；
If c) b) result is the positive, judge detected person very likely for drug abuse suspect.
2. the detection method described in claim 1, wherein, a length of 30 seconds or more when described dark adaptation is fixing, when illumination is fixing
A length of 2 seconds, black out a length of 2 seconds or more when maintaining.
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| CN201410483690.0A CN104545895B (en) | 2014-09-22 | 2014-09-22 | Method for quickly screening out drug addicts by electroencephalogram characteristics |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1248426A (en) * | 1999-10-29 | 2000-03-29 | 清华大学 | Controller based on brain electricity steady-state induced response |
| CN1771881A (en) * | 2005-11-10 | 2006-05-17 | 昆明依利科特科技有限公司 | Quick identification method of the addication and dependance of opium drug addict |
| WO2008137161A2 (en) * | 2007-05-07 | 2008-11-13 | The Trustees Of The University Of Pennsylvania | Concurrent electrophysiologic and cerebral blood flow neuroimaging |
| CN101427915A (en) * | 2008-11-14 | 2009-05-13 | 昆明依利科特科技有限公司 | Human brain status information capture and detection apparatus |
| CN103186765A (en) * | 2011-12-30 | 2013-07-03 | 牟颖 | Method of identifying drug addict in pupil identification mode though mobile phone |
-
2014
- 2014-09-22 CN CN201410483690.0A patent/CN104545895B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1248426A (en) * | 1999-10-29 | 2000-03-29 | 清华大学 | Controller based on brain electricity steady-state induced response |
| CN1771881A (en) * | 2005-11-10 | 2006-05-17 | 昆明依利科特科技有限公司 | Quick identification method of the addication and dependance of opium drug addict |
| WO2008137161A2 (en) * | 2007-05-07 | 2008-11-13 | The Trustees Of The University Of Pennsylvania | Concurrent electrophysiologic and cerebral blood flow neuroimaging |
| CN101427915A (en) * | 2008-11-14 | 2009-05-13 | 昆明依利科特科技有限公司 | Human brain status information capture and detection apparatus |
| CN103186765A (en) * | 2011-12-30 | 2013-07-03 | 牟颖 | Method of identifying drug addict in pupil identification mode though mobile phone |
Non-Patent Citations (1)
| Title |
|---|
| EEG spectral power and mean frequencies in early heroin abstinence;A.G.Polunina,et.al;《Progress in Neuro-Psychopharmacology & Biological Psychiatry》;20041231(第28期);摘要，第75页第1栏第1-4段、第2栏倒数第1段，第77页第1栏第3-5段，第79页第2栏第2-3段，第81页第1栏倒数第1段，附图1-2 * |
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