CN104524395A - Traditional Chinese medicine preparation for treating yang-deficiency type narcolepsy - Google Patents

Abstract

The invention discloses a traditional Chinese medicine preparation for treating yang-deficiency type narcolepsy. The preparation is characterized by being prepared from the following raw materials in parts by weight: 20 parts of david woodbetony rhizome, 20 parts of combined spicebush leaf, 18 parts of alpinia officinarum hance, 18 parts of lactarius insulsus fr, 12 parts of pinewood in poria, 12 parts of woolly lespedeza root, 15 parts of scammoniae radix, 15 parts of crotalaria ferruginea, 15 parts of rubus hirsutus, 15 parts of piper sarmentosum roxb, 10 parts of cinnamomum subavenium, 20 parts of tolypanthus maclurei, 18 parts of elsholtzia cillata hyland, 15 parts of vernonia squarrosa, 10 parts of kohlrabi, 15 parts of pyrola, 15 parts of root of clerodenrum bungei steud and 5 parts of liquorice. Years of application on multiple patients indicate that the traditional Chinese medicine prepared according to the formula of the invention has an effective rate of 100 percent and a good treatment effect, and can be used for preventing relapse after healing.

Description

A kind of Chinese medicine preparation for the treatment of deficiency of yang type disorders of excessive sleepiness

Technical field

The present invention relates to a kind of Chinese medicine, particularly a kind of Chinese medicine preparation being used for the treatment of deficiency of yang type disorders of excessive sleepiness.

Background technology

Drowsinessly refer to day and night, sleepy constantly, that exhales can wake up, the disease of sleeping again after waking up.It is a kind of nervous system disease, it can cause can not inhibition sleep generation.These Sleep stages can often occur, and incident time contretemps, such as, when speaking, having a meal or drive.The traditional Chinese medical science is according to causing the reason of this disease the dialectical treatment of this disease to be divided into type of intense damp, spleen-deficient, blood stasis blocking type, deficiency of yang type four kinds of pattern of syndrome.The Therapeutic Method of disorders of excessive sleepiness has tcm therapy and western medicine therapy, acupuncture and moxibustion therapy etc., western medicine therapy mainly adopts to take stimulants and resembles modafinil(Provigil daytime), the medicines such as toluene salt (Ritalin and other brand names) or dextroamphetamine (Dexedrine), just respite sleepiness, after drug action subsides, enter Somnolence again at once, acupuncture and moxibustion therapy also can play certain effect, but onset is slower, cure rate is lower, tcm therapy is effective Therapeutic Method, because it can be treated from causing the basic reason of disorders of excessive sleepiness to start with, there is the effect reaching treating both the principal and secondary aspects of a disease.The Chinese medicine for the treatment of disorders of excessive sleepiness disclosed at present also exists the defects such as cure rate is lower.

Summary of the invention

The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of deficiency of yang type disorders of excessive sleepiness, adopt Chinese medicine of the present invention, can effectively cure deficiency of yang type disorders of excessive sleepiness, therapeutic effect is good.

The technical scheme adopted for realizing above-mentioned purpose of the present invention is: a kind of Chinese medicine preparation for the treatment of deficiency of yang type disorders of excessive sleepiness, it is characterized in that being made up of the raw material of following weight proportion:

Bitter 18 parts, the newborn mushroom of Rhizoma Pedicularis Davidii 20 parts, Folium Linderae strychnifoliae 20 parts, Rhizoma Alpiniae Galangae 18 parts, ring grain, Lignum Poria 12 parts, Radix Lespedezae Tomentosae 12 parts, Radix Calystegiae sepii 15 parts, Canis familiaris L. jingle bell 15 parts of, Fructus rubi tephrodis 15 parts of, Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 15 parts, 10 parts, fragrant Cortex cinnamomi japonici (Ramulus Cinnamomi), parasitic 20 parts of large bud, Herba Elsholtziae Ciliatae 18 parts, Herba Vernonia squarrosae 15 parts, blue 10 parts of thumb, Herba Pyrolae 15 parts, Radix clerodendri bungei 15 parts, 5 parts, Radix Glycyrrhizae.

Source and the function of various medical materials involved in formula cure mainly as follows:

Rhizoma Pedicularis Davidii [source] is the rhizome of goatweed David Radix seu Herba Pedicularis, rough Radix seu Herba Pedicularis, Deng Shi Radix seu Herba Pedicularis, Radix seu Herba Pedicularis attractive in appearance etc.[nature and flavor] sweet in the mouth; Micro-hardship; Warm in nature; Mild toxicity.[function cures mainly] enriching yin and nourishing kidney; Replenishing QI to invigorate the spleen.Main asthenia of both the spleen and kidney; Osteopyrexia and fever; Arthralgia; Anorexia.

Folium Linderae strychnifoliae [source] medical material Ji Yuan: be the leaf of the canella Radix Linderae.[nature and flavor] are pungent; Temperature.[return through] spleen; Kidney channel.[function cures mainly] warming middle-JIAO is regulated the flow of vital energy; Reducing swelling and alleviating pain.Main coldness and pain in the epigastrium; Frequent micturition; Rheumatic arthralgia; Traumatic pain; Scald.

Rhizoma Alpiniae Galangae [source] medical material Ji Yuan: be the rhizome of zingiberaceous plant Rhizoma Alpiniae Galangae.[nature and flavor] acrid in the mouth; Warm in nature.[function cures mainly] stomach warming; Cold expelling; Promoting the circulation of QI to relieve pain.Main stomachache with cool feeling; Dyspeptic vomiting and diarrhea.

The bitter newborn mushroom Lactarius insulsus Fr. of ring grain bitter newborn mushroom [source] Mycophyta Basidiomycetes Agaricales Russulaceae ring grain, is used as medicine with sporophore.[nature and flavor] are bitter, temperature.[function cures mainly] chases after wind, cold expelling, and relaxing muscles and tendons is active.

Lignum Poria [source] medical material Ji Yuan: be the Radix Pini massonianae in the middle of On Polyporaceae poria cocos sclerotium.[nature and flavor] are sweet; Property is put down.[return through] liver; Heart channel.[function cures mainly] suppressing the hyperactive liver is calmed the nerves.Main palpitation with fear is forgetful; Apoplexy language is not smoothgoing; Beriberi is had a cramp.

Radix Lespedezae Tomentosae [source] medical material Ji Yuan: be the root of leguminous plant mountain tofu pudding.[nature and flavor] are sweet; Micro-light; Property is put down.[return through] spleen channel.[function cures mainly] spleen invigorating tonify deficiency; Clearing away heat-damp and promoting diuresis; Promoting blood flow to regulate menstruation.Main asthenia; Blood deficiency is dizzy; Edema; Ascites; Dysentery; Amenorrhea; Dysmenorrhea.

Radix Calystegiae sepii [source] medical material Ji Yuan: be the root of dicotyledon scammonia section plant bellbine.[nature and flavor] are sweet; Micro-hardship; Temperature.[return through] lung; Liver; Kidney channel.[function cures mainly] QI invigorating tonify deficiency; Reunion of fractured tendons and bones; Removing toxic substances; Parasite killing.Main erysipelas; Strain; Incised wound; Ascariasis.

Canis familiaris L. jingle bell [source] pulse family bullshit bean plant is blue Crotalaria ferruginea Grah. ex Benth. falsely, is used as medicine with herb or root.[nature and flavor] sweet, micro-hardship, flat.[function cures mainly] nourishing the liver nourishing kidney, relieving cough and asthma, regulating menstruation.Have a dizzy spell caused by deficiency of the liver and kindey, Hiccough and deaf, seminal emission, nephritis, bronchitis, asthma, menoxenia, leucorrhea.

The fruit that Fructus rubi tephrodis [source] is rosaceous plant Rubus tephrodes.[nature and flavor] sweet acid, temperature.[function cures mainly] invigorating the liver and kidney, urine reducing.Zhiduo County urinates, the vertigo.

Radix Piperis sarmentosi (Herba Piperis Sarmentosi) [source] medical material Ji Yuan: be the fruit ear of Piperaceae plant Radix Piperis sarmentosi (Herba Piperis Sarmentosi) PipersarmentosumRoxb..[nature and flavor] are pungent; Temperature.[function cures mainly] warming spleen and stomach for dispelling cold; Promoting the circulation of QI to relieve pain; Removing dampness is subsided a swelling.Main abdominal distention; Cold-damp is suffered from diarrhoea; Rheumatic arthralgia; Colicky; Toothache; Edema.

Fragrant Cortex cinnamomi japonici (Ramulus Cinnamomi) [source] medical material Ji Yuan: be the bark in canella perfume osmanthus, root or root bark.[nature and flavor] acrid in the mouth; Warm in nature.[return through] stomach; Spleen; Liver Channel.[function cures mainly] warming spleen and stomach for dispelling cold; Regulating QI to relieve pain; Blood circulation and channel invigorating.Main cold syndrome of the stomach pain; Fullness in the chest is suffered from abdominal pain; Vomiting is had loose bowels; Hernia pain; Traumatic injury; Rheumatic arthralgia; Dysentery hemorrhoidal hamorrhage.

Parasitic [source] medical material Ji Yuan of large bud: be the stem and branch with leaf that the large bud of Loranthaceae plant is parasitic, the large bud in osmanthus, Guizhou Province is parasitic.[nature and flavor] are bitter; Sweet; Tepor.[function cures mainly] invigorating the liver and kidney; Bone and muscle strengthening; Expelling wind and removing dampness.The main vertigo; Soreness of waist and knee joint; Rheumatic numbness.

Herba Elsholtziae Ciliatae [source] medical material Ji Yuan: be the herb of the continuous fringe Soviet Union of labiate.[nature and flavor] acrid in the mouth; Micro-hardship; Warm in nature.[function cures mainly] is dispeled the wind and is delivered; Blood-arresting catamenia-regulating; Subduing swelling and detoxicating.Main flu; Headache; Paralysis; Over-strained hemoptysis; Metrorrhagia; Menoxenia; Dysmenorrhea; Sore and toxic.

Herba Vernonia squarrosae [source] Compositae Herba Vernonia squarrosae Vernonia squarrosa (D. Don) Less. var. orientalis Kitam. [V. teres auct. non DC.], is used as medicine with root.[nature and flavor] are bitter, pungent, are slightly cold.[function cures mainly] strengthening the spleen to promote digestion, pain relieving, dehumidifying, antiinflammatory.

Thumb indigo plant [source] medical material Ji Yuan: be the bulb of crucifer kohlrabi, blade and seed.[nature and flavor] are sweet; Pungent; Cool.[function cures mainly] invigorating spleen to remove dampness; Removing toxic substances.Main edema due to deficiency of the spleen; Stranguria with turbid discharge; Large intestine hematochezia; Damp and hot sore.

The herb that Herba Pyrolae [source] is Pyrolaceae plant Herba pyrolae japonicae or Pylora rotundolia etc.[nature and flavor] sweetness and bitterness, temperature.[return through] enters liver, kidney two warp.[function cures mainly] tonify deficiency, kidney tonifying, expelling wind and removing dampness, promoting blood flow to regulate menstruation, controls weak cough, over-strained hemoptysis, rheumatic arthritis, metrorrhagia, leucorrhea, traumatic hemorrhage.

Radix clerodendri bungei [source] medical material Ji Yuan: be the root of dicotyledon medicine Verbenaceae Caulis et folium clerodendri bungei.[nature and flavor] work hard; Temperature.[return through] liver; Spleen; Kidney; Lung meridian.[function cures mainly] circulation of qi promoting spleen invigorating; Expelling wind and removing dampness; Removing toxic substances and promoting subsidence of swelling; Blood pressure lowering.The stagnant abdominal distention of staple food; Dizzy; Hiss and cough; Outer dysentery proctoptosis; Perianal abscess hematochezia; Stranguria with turbid discharge leukorrhagia; Rheumatalgia; Foot gas; Swollen ulcer drug; Dermatitis rhus; Hypertension.

Radix Glycyrrhizae [source] this product is the dry root of glycyrrhizic legume Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza glabra L..[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.

The clinical symptoms of deficiency of yang type disorders of excessive sleepiness shows as: neurolysis, all day drowsiness lazyness speech, and aversion to cold and cold limbs, complexion is white, forgetful all of a sudden, reposes and is not tired of, large loose stool.Pale tongue with thin fur, deep,thready and forceless pulse.[method for the treatment of] QI invigorating warming YANG.The present invention adopts the formula of science, the Rhizoma Pedicularis Davidii energy enriching yin and nourishing kidney adopted in formula, replenishing QI to invigorate the spleen; Folium Linderae strychnifoliae energy warming middle-JIAO is regulated the flow of vital energy, reducing swelling and alleviating pain; Rhizoma Alpiniae Galangae energy stomach warming, cold expelling, promoting the circulation of QI to relieve pain; The bitter newborn mushroom of ring grain can chase after wind, cold expelling, relaxing muscles and tendons, active; Lignum Poria energy suppressing the hyperactive liver is calmed the nerves; Radix Lespedezae Tomentosae energy spleen invigorating tonify deficiency, clearing away heat-damp and promoting diuresis, promoting blood flow to regulate menstruation; Radix Calystegiae sepii energy QI invigorating tonify deficiency, reunion of fractured tendons and bones; Canis familiaris L. jingle bell energy nourishing the liver nourishing kidney, relieving cough and asthma; The invigorating the liver and kidney of Fructus rubi tephrodis energy, urine reducing; Radix Piperis sarmentosi (Herba Piperis Sarmentosi) energy warming spleen and stomach for dispelling cold, promoting the circulation of QI to relieve pain; Fragrant Cortex cinnamomi japonici (Ramulus Cinnamomi) energy warming spleen and stomach for dispelling cold, regulating QI to relieve pain, blood circulation and channel invigorating; The invigorating the liver and kidney of large bud parasitic energy, bone and muscle strengthening; Herba Elsholtziae Ciliatae can dispel the wind and deliver, blood-arresting catamenia-regulating, subduing swelling and detoxicating; Herba Vernonia squarrosae energy strengthening the spleen to promote digestion, pain relieving, dehumidifying, antiinflammatory; Thumb blue energy invigorating spleen to remove dampness; Herba Pyrolae energy tonify deficiency, kidney tonifying, expelling wind and removing dampness, promoting blood flow to regulate menstruation; Radix clerodendri bungei energy circulation of qi promoting spleen invigorating, blood pressure lowering; Radix Glycyrrhizae energy invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Can cooperatively interact between each medicine in formula, synergism, made Chinese medicine has effect of QI invigorating warming YANG, can effectively treat deficiency of yang type disorders of excessive sleepiness, for many years, by showing the use of 40 patients, effective percentage reaches 100%, cure rate reaches 98%, and therapeutic effect is good, no longer recurs more.

Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:

1, sampling approach

Be diagnosed as the patient of deficiency of yang type disorders of excessive sleepiness from my unit over nearly 10 years, the routine patient of random selecting 80, wherein, man 40 example, female 40 example, age 38-80 year, clinical symptoms shows as: neurolysis, all day drowsiness lazyness speech, aversion to cold and cold limbs, complexion is white, forgetful all of a sudden, reposes and is not tired of, large loose stool.Pale tongue with thin fur, deep,thready and forceless pulse.Be divided into matched group and treatment group at random, often organize each 50 people.The data there was no significant differences such as two groups of ages, have comparability.

2, test method

2.1 matched group patients take main formula Fuzi Lizhong Wan (Chen Shiwen etc. " formulary of peaceful benevolent dispensary ") plus-minus.Prescription: Radix Aconiti Lateralis Preparata 12 grams, Rhizoma Zingiberis 10 grams, Radix Codonopsis 20 grams, the Radix Astragali 18 grams, Radix Morindae Officinalis 12 grams, Rhizoma Cimicifugae 6 grams, Herba Epimedii 15 grams, Radix Glycyrrhizae Preparata 6 grams.Be decocted in water for oral dose.By specification is taken, 20 days courses for the treatment of.

The oral the present invention of 2.2 treatment group according to the obtained capsule of specific embodiment 1, early, middle and late each once.20 days courses for the treatment of.

3, criterion of therapeutical effect and therapeutic outcome

3.1 criterions of therapeutical effect:

Clinical recovery: clinical symptoms, the sign of deficiency of yang type disorders of excessive sleepiness disappear or substantially disappear; Effective: clinical symptoms, the sign of deficiency of yang type disorders of excessive sleepiness are obviously improved; Effective: clinical symptoms, the sign of deficiency of yang type disorders of excessive sleepiness all take a favorable turn; Invalid: clinical symptoms, the sign of deficiency of yang type disorders of excessive sleepiness are all not improved or increase the weight of.

3.2 treatment statistical results are in table 1.

Table 1 liang group comparitive study

As can be seen here, the medicine adopting prescription of the present invention obtained can safe and effective treatment deficiency of yang type disorders of excessive sleepiness.

Detailed description of the invention

Below in conjunction with the concrete example implemented, further detailed description is done to the present invention.

Embodiment 1

Take Rhizoma Pedicularis Davidii 20 grams, Folium Linderae strychnifoliae 20 grams, Rhizoma Alpiniae Galangae 18 grams, bitter 18 grams, the newborn mushroom of ring grain, Lignum Poria 12 grams, Radix Lespedezae Tomentosae 12 grams, Radix Calystegiae sepii 15 grams, Canis familiaris L. jingle bell 15 grams of, Fructus rubi tephrodis 15 grams of, Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 15 grams, 10 grams, fragrant Cortex cinnamomi japonici (Ramulus Cinnamomi), parasitic 20 grams of large bud, Herba Elsholtziae Ciliatae 18 grams, Herba Vernonia squarrosae 15 grams, blue 10 grams of thumb, Herba Pyrolae 15 grams, Radix clerodendri bungei 15 grams, 5 grams, Radix Glycyrrhizae, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's 1 day consumption must be met.

Be used for the treatment of deficiency of yang type disorders of excessive sleepiness.Oral, every bu is taken for early, middle and late three times.

Specific embodiment 2

Take Rhizoma Pedicularis Davidii 20 grams, Folium Linderae strychnifoliae 20 grams, Rhizoma Alpiniae Galangae 18 grams, bitter 18 grams, the newborn mushroom of ring grain, Lignum Poria 12 grams, Radix Lespedezae Tomentosae 12 grams, Radix Calystegiae sepii 15 grams, Canis familiaris L. jingle bell 15 grams of, Fructus rubi tephrodis 15 grams of, Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 15 grams, 10 grams, fragrant Cortex cinnamomi japonici (Ramulus Cinnamomi), parasitic 20 grams of large bud, Herba Elsholtziae Ciliatae 18 grams, Herba Vernonia squarrosae 15 grams, blue 10 grams of thumb, Herba Pyrolae 15 grams, Radix clerodendri bungei 15 grams, 5 grams, Radix Glycyrrhizae, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's 1 day consumption.

Be used for the treatment of deficiency of yang type disorders of excessive sleepiness.Oral, every bu is taken for early, middle and late three times.

Specific embodiment 3

Take Rhizoma Pedicularis Davidii 20 grams, Folium Linderae strychnifoliae 20 grams, Rhizoma Alpiniae Galangae 18 grams, bitter 18 grams, the newborn mushroom of ring grain, Lignum Poria 12 grams, Radix Lespedezae Tomentosae 12 grams, Radix Calystegiae sepii 15 grams, Canis familiaris L. jingle bell 15 grams of, Fructus rubi tephrodis 15 grams of, Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 15 grams, 10 grams, fragrant Cortex cinnamomi japonici (Ramulus Cinnamomi), parasitic 20 grams of large bud, Herba Elsholtziae Ciliatae 18 grams, Herba Vernonia squarrosae 15 grams, blue 10 grams of thumb, Herba Pyrolae 15 grams, Radix clerodendri bungei 15 grams, 5 grams, Radix Glycyrrhizae, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, granulate according to this area common process, packaging, must meet the granule of adult normal's 1 day consumption.

Be used for the treatment of deficiency of yang type disorders of excessive sleepiness.Oral, every bu is taken for early, middle and late three times.

Claims (1)

1. treat a deficiency of yang type disorders of excessive sleepiness's Chinese medicine preparation, it is characterized in that being made up of the raw material of following weight proportion:

Bitter 18 parts, the newborn mushroom of Rhizoma Pedicularis Davidii 20 parts, Folium Linderae strychnifoliae 20 parts, Rhizoma Alpiniae Galangae 18 parts, ring grain, Lignum Poria 12 parts, Radix Lespedezae Tomentosae 12 parts, Radix Calystegiae sepii 15 parts, Canis familiaris L. jingle bell 15 parts of, Fructus rubi tephrodis 15 parts of, Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 15 parts, 10 parts, fragrant Cortex cinnamomi japonici (Ramulus Cinnamomi), parasitic 20 parts of large bud, Herba Elsholtziae Ciliatae 18 parts, Herba Vernonia squarrosae 15 parts, blue 10 parts of thumb, Herba Pyrolae 15 parts, Radix clerodendri bungei 15 parts, 5 parts, Radix Glycyrrhizae.