CN104524380A - Medicine used for relieving itching, and preparation method thereof - Google Patents

Medicine used for relieving itching, and preparation method thereof Download PDF

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Publication number
CN104524380A
CN104524380A CN201410678715.2A CN201410678715A CN104524380A CN 104524380 A CN104524380 A CN 104524380A CN 201410678715 A CN201410678715 A CN 201410678715A CN 104524380 A CN104524380 A CN 104524380A
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parts
medicine
radix
herba
cortex
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CN104524380B (en
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印和平
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Sansui national medical clinic
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SANSUI NATIONAL TRADITIONAL CHINESE AND WESTERN MEDICINE COMBINED CLINIC
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13—Coniferophyta (gymnosperms)
    • A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234—Cnidium (snowparsley)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288—Taraxacum (dandelion)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/756—Phellodendron, e.g. corktree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/904—Stemonaceae (Stemona family), e.g. croomia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants

Abstract

The invention discloses a medicine used for relieving itching. The medicine is prepared from following medicine raw materials, by weight, 17 to 23 parts of a traditional Chinese medicine named Tianzhendizhen, 17 to 23 parts of a traditional Chinese medicine named Guimilazi, 12 to 17 parts of herba polygoni perfoliati, 27 to 34 parts of tuber fleeceflower stem, 27 to 34 parts of senecio scandens Ham., 12 to 17 parts of alums, 17 to 23 parts of radix sophorae flavescentis, 17 to 23 parts of radix stemonae, 12 to 17 parts of selinum japenious seed, 7 to 13 parts of gallnut, 12 to 17 parts of fructus kochiae, 12 to 17 parts of lonicera japonica, 27 to 34 parts of cynanchum paniculatum, 12 to 17 parts of cortex phellodendri, 12 to 17 parts of dandelion, and 12 to 17 parts of cortex pseudolaricis. The medicine can be used for treating whole body skin prurigo and chronic urticaria. Curative effect is excellent, and side effect is not obvious.

Description

A kind of antipruritic medicine and preparation method thereof
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of antipruritic medicine.
Background technology
Dermatosis is the commonly encountered diseases in daily life, and especially various pruritus, brings misery and inconvenience to patient.
General pruritus is often the occurring together or onset symptoms of many general diseases, as uremia, biliary cirrhosis, hyperthyroidism or go down, diabetes, malignant tumor and neuropsychiatric pruritus etc.The exopathogenic factor of general pruritus and environmental factors (comprising the biological or chemical material incentive in humidity, season, working environment), external used medicine, to cause xerosis cutis etc. with the sebaceous gland of the strong soap of alkalescence and patient skin and sweat gland secretion hypofunction relevant.
The cause of disease of local pruritus is sometimes identical with general pruritus, as diabetes.Pruritus ani is how relevant with enterobiasis, blood stasis, anal fistula etc.Vulval pruritus is how relevant with leucorrhea, trichomonal vaginitis, vaginal thrush, gonorrhea and cervical cancer.Scrotal pruritus normal with locally Pi Wengao, hyperhidrosis, friction, fungal infection be relevant.The generation of pruritus mainly by chemical mediator caused by the release of histamine, Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2, kassinin kinin and protease etc.
At present, market has much for antipruritic medicine, comprise oral medicine and medicine for external use.The former is applicable to large area skin pruritus or general pruritus, as white three rare antagonist classes woods slow releasing tablet controlled by ware, montelukast receives sheet, nachr antagonist, chlorphenamine, loratadine etc.; The latter is applicable to small size pruritus, as cetirizine, triprolidine etc.The how applicable external wash liquid of vulval pruritus, circulating in market more has JIEERYIN, woman scorching clean etc.But these medicines have not as people's will part more, or relapse rate is high or onset is slow or side effect is large or zest is large etc.
Summary of the invention
The object of the present invention is to provide a kind of good effect, the antipruritic medicine that side effect is little.
Medicine of the present invention is prepared by the crude drug of following weight proportion:
It pin ground pin 17-23 part, terrible rice spicy 17-23 part, Herba Lespedezae Cuneatae 12-17 part, Caulis Polygoni Multiflori 27-34 part, Herba Senecionis Scandentis 27-34 part, Alumen 12-17 part, Radix Sophorae Flavescentis 17-23 part, Radix Stemonae 17-23 part, Fructus Cnidii 12-17 part, Galla Chinensis 7-13 part, Fructus Kochiae 12-17 part, Flos Lonicerae 12-17 part, Radix Cynanchi Paniculati 27-34 part, Cortex Phellodendri 12-17 part, Herba Taraxaci 12-17 part, Cortex Pseudolaricis 12-17 part.
The preferred weight proportioning of above-mentioned raw materials medicine is:
It 20 parts, pin in pin ground, 20 parts, terrible rice spicy, Herba Lespedezae Cuneatae 15 parts, Caulis Polygoni Multiflori 30 parts, Herba Senecionis Scandentis 30 parts, 15 parts, Alumen, Radix Sophorae Flavescentis 20 parts, the Radix Stemonae 20 parts, Fructus Cnidii 15 parts, Galla Chinensis 10 parts, the Fructus Kochiae 15 parts, Flos Lonicerae 15 parts, Radix Cynanchi Paniculati 30 parts, Cortex Phellodendri 15 parts, Herba Taraxaci 15 parts, Cortex Pseudolaricis 15 parts.
The present invention compared with prior art, there is obvious beneficial effect, as can be known from the above technical solutions: the present invention selects a day pin ground pin, terrible rice spicy, Herba Lespedezae Cuneatae, Caulis Polygoni Multiflori, Herba Senecionis Scandentis, Alumen, Radix Sophorae Flavescentis, the Radix Stemonae, Fructus Cnidii, Galla Chinensis, the Fructus Kochiae, Flos Lonicerae, Radix Cynanchi Paniculati, Cortex Phellodendri, Herba Taraxaci, Cortex Pseudolaricis to be raw material, play antipruritic effect by the synergism between each medicine, can effectively treat pruritus vulvae, skin eczema, tinea manus and pedis, tinea corporis, urticaria etc.Its good effect, side effect are little, and medication is convenient and swift.Clinical totally 600 examples use, and effective percentage is 90%.
Detailed description of the invention
The beneficial effect of medicine of the present invention is set forth further below by way of test example.
test example:the clinical observation of medicine of the present invention
Clinical data:
All cases 600 example.
Wherein, pruritus vulvae patient 500 example, women; Skin eczema patient 100 example, male 50 example, women 50 example.
Diagnostic criteria:
" disease of tcm Standardization of diagnosis and curative effect "
Therapeutic Method:
Pruritus vulvae patient:
(1) get medicine of the present invention, add water 2 liters, boil rear slow fire and keep 30 minutes;
(2) medicinal liquid is poured in basin, first smoked external genital, demibain 20 minutes after water temperature is suitable;
(3) with irrigator rinsing vulva road.
Once a day, 7 days courses for the treatment of, general 1-3 course for the treatment of.
Skin eczema patient:
(1) get medicine of the present invention, decoct with water, until residue 2 Hydrargyri Oxydum Rubrum liquid;
(2) 15 minutes, washout affected part.
Once a day, 7 days courses for the treatment of, general 1-3 course for the treatment of
Criterion of therapeutical effect:
Effective: transference cure
Effective: symptom is obviously alleviated
Invalid: symptom is without improvement or increase the weight of.
Therapeutic outcome:
The routine patient of pruritus vulvae 500 is through Drug therapy of the present invention, and effective 450 is routine, invalid 50 examples, effective percentage 90%;
The routine patient of skin eczema 100 is through Drug therapy of the present invention, and effective 90 examples, invalid 10 is routine, effective percentage 90%.
embodiment 1
Take a day pin ground pin 17g, terrible rice spicy 17g, Herba Lespedezae Cuneatae 17g, Caulis Polygoni Multiflori 34g, Herba Senecionis Scandentis 27g, Alumen 12g, Radix Sophorae Flavescentis 23g, Radix Stemonae 23g, Fructus Cnidii 12g, Galla Chinensis 7g, Fructus Kochiae 12g, Flos Lonicerae 17g, Radix Cynanchi Paniculati 34g, Cortex Phellodendri 12g, Herba Taraxaci 12g, Cortex Pseudolaricis 12g, clean, decoct with water and get final product.
embodiment 2
Take a day pin ground pin 23g, terrible rice spicy 23g, Herba Lespedezae Cuneatae 12g, Caulis Polygoni Multiflori 27g, Herba Senecionis Scandentis 34g, Alumen 17g, Radix Sophorae Flavescentis 17g, Radix Stemonae 17g, Fructus Cnidii 17g, Galla Chinensis 13g, Fructus Kochiae 17g, Flos Lonicerae 12g, Radix Cynanchi Paniculati 27g, Cortex Phellodendri 17g, Herba Taraxaci 17g, Cortex Pseudolaricis 17g, clean, decoct with water and get final product.
embodiment 3
Take a day pin ground pin 19g, terrible rice spicy 19g, Herba Lespedezae Cuneatae 16g, Caulis Polygoni Multiflori 32g, Herba Senecionis Scandentis 32g, Alumen 16g, Radix Sophorae Flavescentis 19g, Radix Stemonae 19g, Fructus Cnidii 16g, Galla Chinensis 8g, Fructus Kochiae 16g, Flos Lonicerae 16g, Radix Cynanchi Paniculati 32g, Cortex Phellodendri 16g, Herba Taraxaci 16g, Cortex Pseudolaricis 16g, clean, decoct with water and get final product.
embodiment 4
Take a day pin ground pin 20g, terrible rice spicy 20g, Herba Lespedezae Cuneatae 15g, Caulis Polygoni Multiflori 30g, Herba Senecionis Scandentis 30g, Alumen 15g, Radix Sophorae Flavescentis 20g, Radix Stemonae 20g, Fructus Cnidii 15g, Galla Chinensis 10g, Fructus Kochiae 15g, Flos Lonicerae 15g, Radix Cynanchi Paniculati 30g, Cortex Phellodendri 15g, Herba Taraxaci 15g, Cortex Pseudolaricis 15g, clean, decoct with water and get final product.

Claims (2)

1. an antipruritic medicine, is made up of the crude drug of following weight proportioning: sky pin ground pin 17-23 part, terrible rice spicy 17-23 part, Herba Lespedezae Cuneatae 12-17 part, Caulis Polygoni Multiflori 27-34 part, Herba Senecionis Scandentis 27-34 part, Alumen 12-17 part, Radix Sophorae Flavescentis 17-23 part, Radix Stemonae 17-23 part, Fructus Cnidii 12-17 part, Galla Chinensis 7-13 part, Fructus Kochiae 12-17 part, Flos Lonicerae 12-17 part, Radix Cynanchi Paniculati 27-34 part, Cortex Phellodendri 12-17 part, Herba Taraxaci 12-17 part, Cortex Pseudolaricis 12-17 part.
2. medicine antipruritic as claimed in claim 1, is characterized in that: be made up of the crude drug of following weight proportioning: 20 parts, the pin in sky pin ground, 20 parts, terrible rice spicy, Herba Lespedezae Cuneatae 15 parts, Caulis Polygoni Multiflori 30 parts, Herba Senecionis Scandentis 30 parts, 15 parts, Alumen, Radix Sophorae Flavescentis 20 parts, the Radix Stemonae 20 parts, Fructus Cnidii 15 parts, Galla Chinensis 10 parts, the Fructus Kochiae 15 parts, Flos Lonicerae 15 parts, Radix Cynanchi Paniculati 30 parts, Cortex Phellodendri 15 parts, Herba Taraxaci 15 parts, Cortex Pseudolaricis 15 parts.
CN201410678715.2A 2014-11-24 2014-11-24 A kind of antipruritic medicine and preparation method thereof Expired - Fee Related CN104524380B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109260294A (en) * 2018-11-16 2019-01-25 韦建成 A kind of Chinese medicine composition for treating eczema

Citations (2)

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Publication number Priority date Publication date Assignee Title
EP1366783B1 (en) * 2002-05-28 2006-04-05 CHEN, Bih Cheng Medicinal herbal preparation for disinfecting vaginas
CN102048876A (en) * 2009-11-05 2011-05-11 天津开发区太人生物科技有限公司 Bagged external washing ointment for assisting treatment of gynecologic inflammation and itchiness and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1366783B1 (en) * 2002-05-28 2006-04-05 CHEN, Bih Cheng Medicinal herbal preparation for disinfecting vaginas
CN102048876A (en) * 2009-11-05 2011-05-11 天津开发区太人生物科技有限公司 Bagged external washing ointment for assisting treatment of gynecologic inflammation and itchiness and preparation method thereof

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Title
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109260294A (en) * 2018-11-16 2019-01-25 韦建成 A kind of Chinese medicine composition for treating eczema

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