CN104524318A - Red ginseng, astragalus membranaceus and lalang grass rhizome mixture and preparation method of mixture - Google Patents

Red ginseng, astragalus membranaceus and lalang grass rhizome mixture and preparation method of mixture Download PDF

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CN104524318A
CN104524318A CN201510043852.3A CN201510043852A CN104524318A CN 104524318 A CN104524318 A CN 104524318A CN 201510043852 A CN201510043852 A CN 201510043852A CN 104524318 A CN104524318 A CN 104524318A
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parts
mixture
medicinal residues
medicine juice
radix
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方居正
夏艳斐
高颖
虞颖茜
吕春延
方菲芃
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
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    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • A61K36/428Trichosanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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Abstract

The invention provides a red ginseng, astragalus membranaceus and lalang grass rhizome mixture and a preparation method of the mixture. The mixture is prepared from the following raw materials in parts by weight: 10-20 parts of red ginseng, 25-35 parts of astragalus membranaceus, 10-20 parts of pericarpium arecae, 25-35 parts of exocarpium benincasae, 25-35 parts of lalang grass rhizome, 5-15 parts of trichosanthes kirilowii Maxim, 10-20 parts of grifola, 10-20 parts of herba lycopi, 10-20 parts of cortex mori radicis, 2-4 parts of asarum, 10-20 parts of rhizoma corydalis, 10-20 parts of salviae miltiorrhizae, 10-20 parts of poria and 4-8 parts of honey-fried licorice roots. The mixture provided by the invention has the effects of strengthening heart and improving the cardiac function. The mixture provided by the invention focuses on dituesis and aims to alleviate the burden of the heart. Moreover, through existing pharmacological study and clinical test observation, the effect of the mixture for alleviating the burden of the heart is remarkable.

Description

A kind of Radix Ginseng Rubra stilbene thatch mixture and preparation method thereof
Technical field
The invention belongs to technical field of traditional Chinese medicine preparation, relate to a kind of Radix Ginseng Rubra stilbene thatch mixture being used for the treatment of chronic heart failure disease and preparation method thereof specifically.
Background technology
The Chinese medicine of existing treatment chronic heart failure is numerous, and its major part only payes attention to the therapeutical effect of QI invigorating warming YANG, but payes attention to not enough for diuretic, the problems such as the therapeutic effect causing the Chinese medicine of existing treatment chronic heart failure is not good, and the treatment phase is longer.
Summary of the invention
The object of the invention is to just provide a kind of Radix Ginseng Rubra stilbene thatch mixture being used for the treatment of chronic heart failure disease and preparation method thereof to above-mentioned the deficiencies in the prior art part.
The present invention realizes the technical scheme that above-mentioned purpose takes: a kind of Radix Ginseng Rubra stilbene thatch mixture, and it comprises the raw material of following parts by weight, Radix Ginseng Rubra 10-20 part, Radix Astragali 25-35 part, Pericarpium Arecae 10-20 part, Exocarpium Benincasae 25-35 part, Rhizoma Imperatae 25-35 part, Fructus Trichosanthis 5-15 part, Polyporus 10-20 part, Herba Lycopi 10-20 part, Cortex Mori 10-20 part, Herba Asari 2-4 part, Rhizoma Corydalis 10-20 part, Radix Salviae Miltiorrhizae 10-20 part, Poria 10-20 part, Radix Glycyrrhizae Preparata 4-8 part.
The preparation method of above-mentioned Radix Ginseng Rubra stilbene thatch mixture comprises the following steps:
A, by medical material in proportion number mixing after, insert in high-pressure sealed boiling machine, add 10 times to the distilled water of medical material total amount, soak 50-70 minute;
B, unlatching boiling machine starting switch, decocting herbs 1.5-2.5 hour, filters medicinal residues, extracts medicine juice for subsequent use;
C, by filter gained medicinal residues in again add 8 times to the distilled water of medicinal residues weight, secondary decoct 1-2 hour, filter medicinal residues, extract medicine juice;
D, b and step c gained medicine juice fully to be mixed, carry out third time and heat concentrated, be concentrated into 1/2 of total dose, adopt high temperature sterilize technology to carry out sterilizing;
E, medicine juice is loaded in pop can filling machine, special aluminium ring pull end is placed in filling machine opening part, carries out medicinal liquid subpackage, every tank 250ml.
Pharmacology of the present invention and beneficial effect are: mixture of the present invention with QI invigorating warming YANG for principle for the treatment of, evident in efficacy to chronic heart failure; The formula compatibility of mixture of the present invention is reasonable, consumption is accurate, this formula gives prominence to the diuretic effect of Pericarpium Arecae, Exocarpium Benincasae, Rhizoma Imperatae, Pericarpium Arecae: pungent, warm, returns lung, taste, intestine and small intestine warp, can open lung qi dispersing gas, inducing diuresis to remove edema, Compendium of Material Medica is recorded, and Pericarpium Arecae can " lowering the adverse flow of QI, aqueous vapor edema in the skin that disappears ".Exocarpium Benincasae: sweet, cool, return lung, small intestine meridian, can heat clearing away de-swelling, inducing diuresis to remove edema, " property of medicine cuts use " is recorded: " between row spleen, water wets, the kind skin that disappears ".Rhizoma Imperatae: sweet, cold, return lung, stomach, urinary bladder channel, can inducing diuresis for treating stranguria syndrome, inducing diuresis to remove edema.Ancient medicine speech wherein has joint in vain, and the water of kind sharp joint wets, the same use of three medicines, and the water of upper, middle and lower three Jiao is wet with profit, and the pathogenic water of Pi Jian, skin, joint is with driving.And dosage ratio is accurate.The present invention has heart tonifying, improves the effect of cardiac function; The present invention focuses on diuretic, is intended to lightening heart load; And through present pharmaceutical research and Clinical observation, its lightening heart load Be very effective; Heart guideline of prevention and treatment is pointed out: diuresis is " foundation stone " of heart failure treatment, and the present invention meets the requirement of modern guide treatment heart failure.
Detailed description of the invention
The present invention is further described below with reference to embodiment.
Embodiment 1
Radix Ginseng Rubra stilbene thatch mixture of the present invention, it comprises the raw material of following parts by weight, Radix Ginseng Rubra 10 parts, the Radix Astragali 25 parts, Pericarpium Arecae 10 parts, Exocarpium Benincasae 25 parts, Rhizoma Imperatae 25 parts, Fructus Trichosanthis 5 parts, Polyporus 10 parts, Herba Lycopi 10 parts, Cortex Mori 10 parts, Herba Asari 2 parts, Rhizoma Corydalis 10 parts, Radix Salviae Miltiorrhizae 10 parts, Poria 10 parts, Radix Glycyrrhizae Preparata 4 parts.
The preparation method of above-mentioned Radix Ginseng Rubra stilbene thatch mixture comprises the following steps:
A, by medical material in proportion number mixing after, insert in high-pressure sealed boiling machine, add 10 times to the distilled water of medical material total amount, soak 50 minutes;
B, unlatching boiling machine starting switch, decocting herbs 1.5 hours, filter medicinal residues, extract medicine juice for subsequent use;
C, by filter gained medicinal residues in again add 8 times to the distilled water of medicinal residues weight, secondary decocts 1 hour, filter medicinal residues, extract medicine juice;
D, b and step c gained medicine juice fully to be mixed, carry out third time and heat concentrated, be concentrated into 1/2 of total dose, adopt high temperature sterilize technology to carry out sterilizing;
E, medicine juice is loaded in pop can filling machine, special aluminium ring pull end is placed in filling machine opening part, carries out medicinal liquid subpackage, every tank 250ml.
Embodiment 2
Radix Ginseng Rubra stilbene thatch mixture of the present invention, it comprises the raw material of following parts by weight, Radix Ginseng Rubra 12 parts, the Radix Astragali 27 parts, Pericarpium Arecae 12 parts, Exocarpium Benincasae 27 parts, Rhizoma Imperatae 27 parts, Fructus Trichosanthis 7 parts, Polyporus 12 parts, Herba Lycopi 12 parts, Cortex Mori 12 parts, Herba Asari 2 parts, Rhizoma Corydalis 12 parts, Radix Salviae Miltiorrhizae 12 parts, Poria 12 parts, Radix Glycyrrhizae Preparata 5 parts.
The preparation method of above-mentioned Radix Ginseng Rubra stilbene thatch mixture comprises the following steps:
A, by medical material in proportion number mixing after, insert in high-pressure sealed boiling machine, add 10 times to the distilled water of medical material total amount, soak 55 minutes;
B, unlatching boiling machine starting switch, decocting herbs 2 hours, filter medicinal residues, extract medicine juice for subsequent use;
C, by filter gained medicinal residues in again add 8 times to the distilled water of medicinal residues weight, secondary decocts 1.5 hours, filter medicinal residues, extract medicine juice;
D, b and step c gained medicine juice fully to be mixed, carry out third time and heat concentrated, be concentrated into 1/2 of total dose, adopt high temperature sterilize technology to carry out sterilizing;
E, medicine juice is loaded in pop can filling machine, special aluminium ring pull end is placed in filling machine opening part, carries out medicinal liquid subpackage, every tank 250ml.
Embodiment 3
Radix Ginseng Rubra stilbene thatch mixture of the present invention, it comprises the raw material of following parts by weight, Radix Ginseng Rubra 15 parts, the Radix Astragali 30 parts, Pericarpium Arecae 15 parts, Exocarpium Benincasae 30 parts, Rhizoma Imperatae 30 parts, Fructus Trichosanthis 10 parts, Polyporus 15 parts, Herba Lycopi 15 parts, Cortex Mori 15 parts, Herba Asari 3 parts, Rhizoma Corydalis 15 parts, Radix Salviae Miltiorrhizae 15 parts, Poria 15 parts, Radix Glycyrrhizae Preparata 6 parts.
The preparation method of above-mentioned Radix Ginseng Rubra stilbene thatch mixture comprises the following steps:
A, by medical material in proportion number mixing after, insert in high-pressure sealed boiling machine, add 10 times to the distilled water of medical material total amount, soak 60 minutes;
B, unlatching boiling machine starting switch, decocting herbs 2 hours, filter medicinal residues, extract medicine juice for subsequent use;
C, by filter gained medicinal residues in again add 8 times to the distilled water of medicinal residues weight, secondary decocts 1.5 hours, filter medicinal residues, extract medicine juice;
D, b and step c gained medicine juice fully to be mixed, carry out third time and heat concentrated, be concentrated into 1/2 of total dose, adopt high temperature sterilize technology to carry out sterilizing;
E, medicine juice is loaded in pop can filling machine, special aluminium ring pull end is placed in filling machine opening part, carries out medicinal liquid subpackage, every tank 250ml.
Embodiment 4
Radix Ginseng Rubra stilbene thatch mixture of the present invention, it comprises the raw material of following parts by weight, Radix Ginseng Rubra 17 parts, the Radix Astragali 32 parts, Pericarpium Arecae 17 parts, Exocarpium Benincasae 32 parts, Rhizoma Imperatae 32 parts, Fructus Trichosanthis 12 parts, Polyporus 17 parts, Herba Lycopi 17 parts, Cortex Mori 17 parts, Herba Asari 3 parts, Rhizoma Corydalis 17 parts, Radix Salviae Miltiorrhizae 17 parts, Poria 17 parts, Radix Glycyrrhizae Preparata 7 parts.
The preparation method of above-mentioned Radix Ginseng Rubra stilbene thatch mixture comprises the following steps:
A, by medical material in proportion number mixing after, insert in high-pressure sealed boiling machine, add 10 times to the distilled water of medical material total amount, soak 60 minutes;
B, unlatching boiling machine starting switch, decocting herbs 2 hours, filter medicinal residues, extract medicine juice for subsequent use;
C, by filter gained medicinal residues in again add 8 times to the distilled water of medicinal residues weight, secondary decocts 1.5 hours, filter medicinal residues, extract medicine juice;
D, b and step c gained medicine juice fully to be mixed, carry out third time and heat concentrated, be concentrated into 1/2 of total dose, adopt high temperature sterilize technology to carry out sterilizing;
E, medicine juice is loaded in pop can filling machine, special aluminium ring pull end is placed in filling machine opening part, carries out medicinal liquid subpackage, every tank 250ml.
Embodiment 5
Radix Ginseng Rubra stilbene thatch mixture of the present invention, it comprises the raw material of following parts by weight, Radix Ginseng Rubra 20 parts, the Radix Astragali 35 parts, Pericarpium Arecae 20 parts, Exocarpium Benincasae 35 parts, Rhizoma Imperatae 35 parts, Fructus Trichosanthis 15 parts, Polyporus 20 parts, Herba Lycopi 20 parts, Cortex Mori 20 parts, Herba Asari 4 parts, Rhizoma Corydalis 20 parts, Radix Salviae Miltiorrhizae 20 parts, Poria 20 parts, Radix Glycyrrhizae Preparata 8 parts.
The preparation method of above-mentioned Radix Ginseng Rubra stilbene thatch mixture comprises the following steps:
A, by medical material in proportion number mixing after, insert in high-pressure sealed boiling machine, add 10 times to the distilled water of medical material total amount, soak 70 minutes;
B, unlatching boiling machine starting switch, decocting herbs 2.5 hours, filter medicinal residues, extract medicine juice for subsequent use;
C, by filter gained medicinal residues in again add 8 times to the distilled water of medicinal residues weight, secondary decocts 2 hours, filter medicinal residues, extract medicine juice;
D, b and step c gained medicine juice fully to be mixed, carry out third time and heat concentrated, be concentrated into 1/2 of total dose, adopt high temperature sterilize technology to carry out sterilizing;
E, medicine juice is loaded in pop can filling machine, special aluminium ring pull end is placed in filling machine opening part, carries out medicinal liquid subpackage, every tank 250ml.

Claims (2)

1. a Radix Ginseng Rubra stilbene thatch mixture, is characterized in that: it comprises the raw material of following parts by weight, Radix Ginseng Rubra 10-20 part, Radix Astragali 25-35 part, Pericarpium Arecae 10-20 part, Exocarpium Benincasae 25-35 part, Rhizoma Imperatae 25-35 part, Fructus Trichosanthis 5-15 part, Polyporus 10-20 part, Herba Lycopi 10-20 part, Cortex Mori 10-20 part, Herba Asari 2-4 part, Rhizoma Corydalis 10-20 part, Radix Salviae Miltiorrhizae 10-20 part, Poria 10-20 part, Radix Glycyrrhizae Preparata 4-8 part.
2., for the preparation of a method for Radix Ginseng Rubra stilbene thatch mixture described in claim 1, it is characterized in that: it comprises the following steps:
A, by medical material in proportion number mixing after, insert in high-pressure sealed boiling machine, add 10 times to the distilled water of medical material total amount, soak 50-70 minute;
B, unlatching boiling machine starting switch, decocting herbs 1.5-2.5 hour, filters medicinal residues, extracts medicine juice for subsequent use;
C, by filter gained medicinal residues in again add 8 times to the distilled water of medicinal residues weight, secondary decoct 1-2 hour, filter medicinal residues, extract medicine juice;
D, b and step c gained medicine juice fully to be mixed, carry out third time and heat concentrated, be concentrated into 1/2 of total dose, adopt high temperature sterilize technology to carry out sterilizing;
E, medicine juice is loaded in pop can filling machine, special aluminium ring pull end is placed in filling machine opening part, carries out medicinal liquid subpackage, every tank 250ml.
CN201510043852.3A 2015-01-29 2015-01-29 Red ginseng, astragalus membranaceus and lalang grass rhizome mixture and preparation method of mixture Pending CN104524318A (en)

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