CN104523667A - 复合季铵盐皮肤粘膜消毒剂复配技术 - Google Patents

复合季铵盐皮肤粘膜消毒剂复配技术 Download PDF

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CN104523667A
CN104523667A CN201510015187.7A CN201510015187A CN104523667A CN 104523667 A CN104523667 A CN 104523667A CN 201510015187 A CN201510015187 A CN 201510015187A CN 104523667 A CN104523667 A CN 104523667A
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quaternary ammonium
ammonium salt
long
disinfectant
chain
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蒙建都
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BEIJING ZHONGHAI CHENGDA TECHNOLOGY & TRADE Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02—Amines; Quaternary ammonium compounds
    • A01N33/12—Quaternary ammonium compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
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  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
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  • Animal Behavior & Ethology (AREA)
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Abstract

本发明公开了一种复合季铵盐皮肤黏膜消毒剂的复配技术。为了克服传统的单长链和双长链复合季铵盐无法在低浓度时快速杀菌，或需复配其他有效成分才能实现技术指标，传统消毒剂易燃、易挥发失效的问题，本发明是由①0.1％十二烷基二甲基苄基氯化铵，②1-2％乙二醇苯醚，③10-20％异丙醇，④0.1％丙三醇，⑤0.1％维生素原B5，螯合剂，稳定剂，PH调节剂组成的水溶液(1000mg/L)，在PH值为6.72弱酸性时0.5分钟杀灭所有指示菌，且杀灭率均大于99.999％，杀菌浓度低，毒性为实际无毒级。不易挥发，保存时间长，无刺激、无致敏性、无色、无味、无黄染、无褪色，免水洗，免介质，运输和使用便捷。

Description

复合季铵盐皮肤粘膜消毒剂复配技术
技术领域
本发明涉及一种复合季铵盐皮肤粘膜消毒剂复配技术，特别是可广泛应用于军用、医用、民用、灭菌、抗抑菌生产等领域。
背景技术
目前，传统的单长链和双长链复合季铵盐无法在低浓度时快速杀菌，或复配酒精、戊二醛、邻苯二甲醛、乌洛托品、醋酸氯已定等才能达到技术指标。同时，传统消毒剂存在着易燃性和易挥发失效、有刺激、有致敏性的弊端。
发明内容
为了克服传统的单长链和双长链复合季铵盐无法在低浓度时快速杀菌，或复配酒精、戊二醛、邻苯二甲醛、乌洛托品、醋酸氯已定等才能实现技术指标，传统消毒剂易燃性、易挥发失效、有刺激、有致敏性的不足，本发明提供了一种复合季铵盐皮肤粘膜消毒剂复配技术。
本发明所采用的技术方案是：本发明是由①0.1％十二烷基二甲基苄基氯化铵，②1-2％乙二醇苯醚，③10-20％异丙醇，④0.1％丙三醇，⑤0.1％维生素原B5，螯合剂，稳定剂，PH调节剂组成的水溶液(1000mg/L)，能有效杀灭真菌、酵母菌、霉菌、大肠杆菌、金黄色葡萄球菌、白色念珠菌、铜绿假单胞菌和病毒等，杀菌浓度低，毒性为实际无毒级，对破损皮肤、黏膜和眼睛均无刺激性，对不锈钢、铜、铝等材质无腐蚀性，生物降解性好，对环境友好，克服了传统的单长链和双长链复合季铵盐无法在低浓度时快速杀菌，或需复配酒精、戊二醛、邻苯二甲醛、乌洛托品、醋酸氯已定等才能实现技术指标的问题，本发明的水溶液在1000mg/L，PH值为6.72弱酸性时，0.5分钟杀灭大肠杆菌、金黄色葡萄球菌、白色念珠菌、铜绿假单胞菌和病毒等所有指示菌，杀灭率均大于99.999％，本发明可生产军用、医用、民用卫生消毒剂，制备简便，成本低廉，可用于破损皮肤消毒，无挥发，保存时间可长达5年以上，在战争和自然灾害时可直接处理伤口，采用无介质喷涂，免去棉签等介质，克服了传统消毒剂易燃性、易挥发失效、有刺激、有致敏性的弊端，且具有无色、无味、无黄染、无褪色，免水洗，运输和使用便捷等特点。
与现有技术相比，本发明的有益效果是，含量低，在PH值为6.72弱酸性时0.5分钟杀灭所有指示菌，且杀灭率均大于99.999％，杀菌浓度低，毒性为实际无毒级。不易挥发，保存时间可长达5年以上。无刺激、无致敏性、无色、无味、无黄染、无褪色，免水洗，免介质，运输和使用便捷。

Claims (3)

1.一种复合季铵盐皮肤粘膜消毒剂复配技术，广泛应用于军用、医用、民用、灭菌、抗抑菌生产等领域，其特征在于：本发明是由①0.1％十二烷基二甲基苄基氯化铵，②1-2％乙二醇苯醚，③10-20％异丙醇，④0.1％丙三醇，⑤0.1％维生素原B5，螯合剂，稳定剂，PH调节剂组成的水溶液(1000mg/L)，能有效杀灭真菌、酵母菌、霉菌、大肠杆菌、金黄色葡萄球菌、白色念珠菌、铜绿假单胞菌和病毒等，杀菌浓度低，毒性为实际无毒级，对破损皮肤、黏膜和眼睛均无刺激性，对不锈钢、铜、铝等材质无腐蚀性，生物降解性好，对环境友好，克服了传统的单长链和双长链复合季铵盐无法在低浓度时快速杀菌，或需复配酒精、戊二醛、邻苯二甲醛、乌洛托品、醋酸氯已定等才能实现技术指标的问题，本发明在PH值为6.72弱酸性时，0.5分钟杀灭大肠杆菌、金黄色葡萄球菌、白色念珠菌、铜绿假单胞菌和病毒等所有指示菌，杀灭率均大于99.999％，本发明可生产军用、医用、民用卫生消毒剂，制备简便，成本低廉，可用于破损皮肤消毒，无挥发，保存时间可长达5年以上，在战争和自然灾害时可直接处理伤口，采用无介质喷涂，免去棉签等介质，克服了传统消毒剂易燃性、易挥发失效、有刺激、有致敏性的弊端，且具有无色、无味、无黄染、无褪色，免水洗，运输和使用便捷等特点。
2.根据权利要求1所述的复合季铵盐皮肤黏膜消毒剂复配技术，其特征是：由①0.1％十二烷基二甲基苄基氯化铵，②1-2％乙二醇苯醚，③10-20％异丙醇，④0.1％丙三醇，⑤0.1％维生素原B5组成。
3.根据权利要求1所述的复合季铵盐皮肤黏膜消毒剂复配技术，其特征是：由①0.1％十二烷基二甲基苄基氯化铵，②1-2％乙二醇苯醚，③10-20％异丙醇，④0.1％丙三醇，⑤0.1％维生素原B5组成后用于生产军用、医用、民用卫生消毒剂、抗抑菌剂。
CN201510015187.7A 2015-01-13 2015-01-13 复合季铵盐皮肤粘膜消毒剂复配技术 Pending CN104523667A (zh)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104888002A (zh) * 2015-05-27 2015-09-09 北京爱特普科技有限公司 一种皮肤局部微生态调节剂
CN106580940A (zh) * 2016-12-30 2017-04-26 蒙建都 一种乙二醇苯醚消毒剂复配技术
CN109316536A (zh) * 2018-10-22 2019-02-12 湖南中威制药有限公司 一种皮肤黏膜消毒剂及其制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000063338A1 (en) * 1999-04-16 2000-10-26 Spartan Chemical Company, Inc. Aqueous disinfectant and hard surface cleaning composition and method of use
CN1426681A (zh) * 2001-12-17 2003-07-02 北京燕山石油化工公司研究院 一种含双烷基季铵盐的复合杀菌剂及其应用
CN1476761A (zh) * 2003-07-02 2004-02-25 刘瑞源 液体消毒剂
CN101352164A (zh) * 2008-08-15 2009-01-28 陈波 新型复方季铵盐消毒剂及制备方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000063338A1 (en) * 1999-04-16 2000-10-26 Spartan Chemical Company, Inc. Aqueous disinfectant and hard surface cleaning composition and method of use
CN1426681A (zh) * 2001-12-17 2003-07-02 北京燕山石油化工公司研究院 一种含双烷基季铵盐的复合杀菌剂及其应用
CN1476761A (zh) * 2003-07-02 2004-02-25 刘瑞源 液体消毒剂
CN101352164A (zh) * 2008-08-15 2009-01-28 陈波 新型复方季铵盐消毒剂及制备方法

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104888002A (zh) * 2015-05-27 2015-09-09 北京爱特普科技有限公司 一种皮肤局部微生态调节剂
CN106580940A (zh) * 2016-12-30 2017-04-26 蒙建都 一种乙二醇苯醚消毒剂复配技术
CN109316536A (zh) * 2018-10-22 2019-02-12 湖南中威制药有限公司 一种皮肤黏膜消毒剂及其制备方法

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